TreeWAS – Variant ID: rs55730499

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E78.5 Hyperlipidaemia, unspecified	1.000	0.000
E78.0 Pure hypercholesterolaemia	1.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000
I20.8 Other forms of angina pectoris	1.000	0.000
I20.0 Unstable angina	1.000	0.000
I21.9 Acute myocardial infarction, unspecified	1.000	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	1.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	1.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000
I25.2 Old myocardial infarction	1.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000
I35.0 Aortic (valve) stenosis	1.000	0.000
I73.9 Peripheral vascular disease, unspecified	1.000	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	1.000	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	1.000	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	1.000	0.000
Z95.5 Presence of coronary angioplasty implant and graft	1.000	0.000
Z95.1 Presence of aortocoronary bypass graft	1.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	1.000	0.000
I10 Essential (primary) hypertension	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
I21 Acute myocardial infarction	1.000	0.000
I20 Angina pectoris	1.000	0.000
I35 Nonrheumatic aortic valve disorders	1.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
I60-I69 Cerebrovascular diseases	1.000	0.000
I77.1 Stricture of artery	1.000	0.000
I22 Subsequent myocardial infarction	1.000	0.000
I77 Other disorders of arteries and arterioles	1.000	0.000
I73 Other peripheral vascular diseases	1.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	1.000	0.000
I74 Arterial embolism and thrombosis	1.000	0.000
I50 Heart failure	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	1.000	0.000
I65.2 Occlusion and stenosis of carotid artery	1.000	0.000
I24 Other acute ischaemic heart diseases	0.999	0.001
Chapter XXI Factors influencing health status and contact with health services	0.999	0.001
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.999	0.001
Z92 Personal history of medical treatment	0.999	0.001
# Top node	0.999	0.001
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.999	0.001
I50.1 Left ventricular failure	0.999	0.001
I21.4 Acute subendocardial myocardial infarction	0.998	0.002
I22.9 Subsequent myocardial infarction of unspecified site	0.998	0.002
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.998	0.002
I21.0 Acute transmural myocardial infarction of anterior wall	0.997	0.003
I70 Atherosclerosis	0.997	0.003
Chapter IV Endocrine, nutritional and metabolic diseases	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
I71 Aortic aneurysm and dissection	0.996	0.004
I44 Atrioventricular and left bundle-branch block	0.995	0.005
E70-E90 Metabolic disorders	0.995	0.005
I70.2 Atherosclerosis of arteries of the extremities	0.994	0.006
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.994	0.006
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.992	0.008
Z95.3 Presence of xenogenic heart valve	0.990	0.010
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.989	0.011
I51 Complications and ill-defined descriptions of heart disease	0.988	0.012
I44.0 Atrioventricular block, first degree	0.985	0.015
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.984	0.016
I35.1 Aortic (valve) insufficiency	0.983	0.017
I51.8 Other ill-defined heart diseases	0.980	0.020
Z70-Z76 Persons encountering health services in other circumstances	0.980	0.020
I22.1 Subsequent myocardial infarction of inferior wall	0.980	0.020
I35.2 Aortic (valve) stenosis with insufficiency	0.978	0.022
Z95.0 Presence of cardiac pacemaker	0.978	0.022
S00-S09 Injuries to the head	0.972	0.028
I31 Other diseases of pericardium	0.970	0.030
E50-E64 Other nutritional deficiencies	0.969	0.031
I05-I09 Chronic rheumatic heart diseases	0.964	0.036
I46 Cardiac arrest	0.960	0.040
I35.9 Aortic valve disorder, unspecified	0.959	0.041
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.958	0.042
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.957	0.043
I64 Stroke, not specified as haemorrhage or infarction	0.954	0.046
Z72 Problems related to lifestyle	0.954	0.046
E53 Deficiency of other B group vitamins	0.954	0.046
I24.8 Other forms of acute ischaemic heart disease	0.953	0.047
R07.4 Chest pain, unspecified	0.952	0.048
S06 Intracranial injury	0.951	0.049
R07 Pain in throat and chest	0.949	0.051
I08 Multiple valve diseases	0.948	0.052
I44.7 Left bundle-branch block, unspecified	0.945	0.055
I50.9 Heart failure, unspecified	0.944	0.056
I46.0 Cardiac arrest with successful resuscitation	0.943	0.057
E53.8 Deficiency of other specified B group vitamins	0.943	0.057
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.943	0.057
Z92.4 Personal history of major surgery, not elsewhere classified	0.942	0.058
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.942	0.058
I63 Cerebral infarction	0.941	0.059
Z72.0 Tobacco use	0.934	0.066
I24.9 Acute ischaemic heart disease, unspecified	0.933	0.067
I31.9 Disease of pericardium, unspecified	0.932	0.068
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.927	0.073
E65-E68 Obesity and other hyperalimentation	0.926	0.074
R42 Dizziness and giddiness	0.925	0.075
I21.2 Acute transmural myocardial infarction of other sites	0.920	0.080
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.918	0.082
S06.6 Traumatic subarachnoid haemorrhage	0.916	0.084
I63.9 Cerebral infarction, unspecified	0.909	0.091
I25.5 Ischaemic cardiomyopathy	0.902	0.098
R01 Cardiac murmurs and other cardiac sounds	0.902	0.098
T82.0 Mechanical complication of heart valve prosthesis	0.901	0.099
T20-T25 Burns and corrosions of external body surface, specified by site	0.900	0.100
Z95.4 Presence of other heart-valve replacement	0.900	0.100
R07.0 Pain in throat	0.899	0.101
Z75 Problems related to medical facilities and other health care	0.894	0.106
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.892	0.108
I22.8 Subsequent myocardial infarction of other sites	0.887	0.113
E66 Obesity	0.886	0.114
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.881	0.119
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.877	0.123
S06.2 Diffuse brain injury	0.876	0.124
T92 Sequelae of injuries of upper limb	0.875	0.125
E66.9 Obesity, unspecified	0.873	0.127
Z63 Other problems related to primary support group, including family circumstances	0.872	0.128
I44.6 Other and unspecified fascicular block	0.872	0.128
R07.3 Other chest pain	0.865	0.135
S10-S19 Injuries to the neck	0.864	0.136
T82.3 Mechanical complication of other vascular grafts	0.863	0.137
I08.8 Other multiple valve diseases	0.862	0.138
E78.4 Other hyperlipidaemia	0.857	0.143
R01.1 Cardiac murmur, unspecified	0.856	0.144
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.853	0.147
I60 Subarachnoid haemorrhage	0.850	0.150
E78.2 Mixed hyperlipidaemia	0.849	0.151
I08.0 Disorders of both mitral and aortic valves	0.846	0.154
Z73 Problems related to life-management difficulty	0.846	0.154
I51.3 Intracardiac thrombosis, not elsewhere classified	0.844	0.156
I77.2 Rupture of artery	0.842	0.158
E88 Other metabolic disorders	0.838	0.162
I25.0 Atherosclerotic cardiovascular disease, so described	0.837	0.163
I72 Other aneurysm	0.832	0.168
I44.3 Other and unspecified atrioventricular block	0.829	0.171
S06.20 Diffuse brain injury (without open intracranial wound)	0.822	0.178
Z92.8 Personal history of other medical treatment	0.817	0.183
I31.3 Pericardial effusion (noninflammatory)	0.817	0.183
S01 Open wound of head	0.814	0.186
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.810	0.190
I74.0 Embolism and thrombosis of abdominal aorta	0.808	0.192
I70.0 Atherosclerosis of aorta	0.807	0.193
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.804	0.196
T82.4 Mechanical complication of vascular dialysis catheter	0.802	0.198
R00 Abnormalities of heart beat	0.801	0.199
I71.0 Dissection of aorta [any part]	0.799	0.201
I77.9 Disorder of arteries and arterioles, unspecified	0.799	0.201
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.797	0.203
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.795	0.205
Z82.3 Family history of stroke	0.794	0.206
S70-S79 Injuries to the hip and thigh	0.793	0.207
I25.3 Aneurysm of heart	0.792	0.208
I22.0 Subsequent myocardial infarction of anterior wall	0.791	0.209
Z59 Problems related to housing and economic circumstances	0.790	0.210
R00.1 Bradycardia, unspecified	0.787	0.213
S90-S99 Injuries to the ankle and foot	0.785	0.215
I38 Endocarditis, valve unspecified	0.785	0.215
I25.4 Coronary artery aneurysm	0.784	0.216
Z75.2 Other waiting period for investigation and treatment	0.784	0.216
R04 Haemorrhage from respiratory passages	0.783	0.217
R14 Flatulence and related conditions	0.783	0.217
E73 Lactose intolerance	0.783	0.217
Z57 Occupational exposure to risk-factors	0.783	0.217
I61 Intracerebral haemorrhage	0.783	0.217
Z63.0 Problems in relationship with spouse or partner	0.780	0.220
Z82.2 Family history of deafness and hearing loss	0.778	0.221
I77.0 Arteriovenous fistula, acquired	0.777	0.223
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.777	0.223
Z56 Problems related to employment and unemployment	0.776	0.224
I50.0 Congestive heart failure	0.776	0.224
Z73.9 Problem related to life-management difficulty, unspecified	0.772	0.228
I51.9 Heart disease, unspecified	0.769	0.231
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.768	0.232
I23 Certain current complications following acute myocardial infarction	0.767	0.233
I63.8 Other cerebral infarction	0.766	0.234
Chapter XX External causes of morbidity and mortality	0.762	0.238
I36 Nonrheumatic tricuspid valve disorders	0.762	0.238
S01.9 Open wound of head, part unspecified	0.762	0.238
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.761	0.239
T00-T07 Injuries involving multiple body regions	0.760	0.240
E51 Thiamine deficiency	0.760	0.240
I65.0 Occlusion and stenosis of vertebral artery	0.759	0.241
T92.1 Sequelae of fracture of arm	0.757	0.243
R15 Faecal incontinence	0.754	0.246
Z75.1 Person awaiting admission to adequate facility elsewhere	0.753	0.247
I67 Other cerebrovascular diseases	0.753	0.247
I74.5 Embolism and thrombosis of iliac artery	0.753	0.247
T20 Burn and corrosion of head and neck	0.750	0.250
I21.3 Acute transmural myocardial infarction of unspecified site	0.749	0.251
I11 Hypertensive heart disease	0.747	0.253
R40 Somnolence, stupor and coma	0.745	0.255
S50-S59 Injuries to the elbow and forearm	0.744	0.256
S05 Injury of eye and orbit	0.743	0.257
Z94 Transplanted organ and tissue status	0.743	0.257
S14 Injury of nerves and spinal cord at neck level	0.741	0.259
T82.1 Mechanical complication of cardiac electronic device	0.740	0.260
R01.0 Benign and innocent cardiac murmurs	0.737	0.263
I15 Secondary hypertension	0.735	0.265
E85 Amyloidosis	0.735	0.265
R04.0 Epistaxis	0.734	0.266
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.731	0.269
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.729	0.271
Z64 Problems related to certain psychosocial circumstances	0.729	0.271
I45 Other conduction disorders	0.726	0.274
Z89 Acquired absence of limb	0.726	0.274
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.726	0.274
S03 Dislocation, sprain and strain of joints and ligaments of head	0.726	0.274
I73.0 Raynaud's syndrome	0.725	0.274
I35.8 Other aortic valve disorders	0.725	0.275
I73.8 Other specified peripheral vascular diseases	0.725	0.275
I51.6 Cardiovascular disease, unspecified	0.725	0.275
T21 Burn and corrosion of trunk	0.723	0.277
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.722	0.278
R47-R49 Symptoms and signs involving speech and voice	0.721	0.279
Z76 Persons encountering health services in other circumstances	0.720	0.280
I30 Acute pericarditis	0.719	0.281
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.718	0.282
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.717	0.282
E78.6 Lipoprotein deficiency	0.717	0.283
E78.3 Hyperchylomicronaemia	0.717	0.283
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
I68 Cerebrovascular disorders in diseases classified elsewhere	0.717	0.283
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.717	0.283
I73.1 Thromboangiitis obliterans [Buerger]	0.717	0.283
I77.5 Necrosis of artery	0.717	0.283
I77.4 Coeliac artery compression syndrome	0.717	0.283
I77.3 Arterial fibromuscular dysplasia	0.717	0.283
I13 Hypertensive heart and renal disease	0.717	0.283
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.717	0.283
Z82.1 Family history of blindness and visual loss	0.717	0.283
I74.9 Embolism and thrombosis of unspecified artery	0.717	0.283
I74.8 Embolism and thrombosis of other arteries	0.717	0.283
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.717	0.283
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.717	0.283
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.717	0.283
I65.8 Occlusion and stenosis of other precerebral artery	0.717	0.283
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.717	0.283
I65.1 Occlusion and stenosis of basilar artery	0.717	0.283
I24.1 Dressler's syndrome	0.717	0.283
Z92.9 Personal history of medical treatment, unspecified	0.716	0.284
Z92.5 Personal history of rehabilitation measures	0.716	0.284
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
I70.9 Generalised and unspecified atherosclerosis	0.715	0.285
I70.8 Atherosclerosis of other arteries	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
Z58 Problems related to physical environment	0.715	0.285
I71.8 Aortic aneurysm of unspecified site, ruptured	0.714	0.286
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.714	0.286
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.714	0.286
I71.1 Thoracic aortic aneurysm, ruptured	0.714	0.286
I44.5 Left posterior fascicular block	0.714	0.286
I44.4 Left anterior fascicular block	0.714	0.286
E84 Cystic fibrosis	0.713	0.286
E79 Disorders of purine and pyrimidine metabolism	0.713	0.286
E77 Disorders of glycoprotein metabolism	0.713	0.286
E76 Disorders of glycosaminoglycan metabolism	0.713	0.286
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.713	0.286
E72 Other disorders of amino-acid metabolism	0.713	0.286
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.713	0.286
E70 Disorders of aromatic amino-acid metabolism	0.713	0.286
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.713	0.286
I95-I99 Other and unspecified disorders of the circulatory system	0.713	0.287
T94 Sequelae of injuries involving multiple and unspecified body regions	0.712	0.288
I70.1 Atherosclerosis of renal artery	0.711	0.289
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.711	0.289
E74 Other disorders of carbohydrate metabolism	0.710	0.289
I72.4 Aneurysm of artery of lower extremity	0.709	0.291
I51.5 Myocardial degeneration	0.708	0.292
I51.2 Rupture of papillary muscle, not elsewhere classified	0.708	0.292
I51.0 Cardiac septal defect, acquired	0.708	0.292
Z72.1 Alcohol use	0.708	0.292
R45 Symptoms and signs involving emotional state	0.707	0.293
S01.3 Open wound of ear	0.707	0.293
Z97 Presence of other devices	0.706	0.294
Z70 Counselling related to sexual attitude, behaviour and orientation	0.703	0.297
S06.3 Focal brain injury	0.703	0.297
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.702	0.298
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.702	0.298
I47 Paroxysmal tachycardia	0.702	0.298
Z72.8 Other problems related to lifestyle	0.699	0.301
S02 Fracture of skull and facial bones	0.698	0.302
S01.8 Open wound of other parts of head	0.697	0.303
S08 Traumatic amputation of part of head	0.697	0.303
S07 Crushing injury of head	0.697	0.303
S04 Injury of cranial nerves	0.697	0.303
Z63.8 Other specified problems related to primary support group	0.696	0.304
I31.8 Other specified diseases of pericardium	0.695	0.304
I31.2 Haemopericardium, not elsewhere classified	0.695	0.304
I31.1 Chronic constrictive pericarditis	0.695	0.304
I31.0 Chronic adhesive pericarditis	0.695	0.304
E64 Sequelae of malnutrition and other nutritional deficiencies	0.695	0.305
E63 Other nutritional deficiencies	0.695	0.305
E56 Other vitamin deficiencies	0.695	0.305
E50 Vitamin A deficiency	0.695	0.305
E60 Dietary zinc deficiency	0.695	0.305
E59 Dietary selenium deficiency	0.695	0.305
E58 Dietary calcium deficiency	0.695	0.305
E54 Ascorbic acid deficiency	0.695	0.305
E52 Niacin deficiency [pellagra]	0.695	0.305
Z73.8 Other problems related to life-management difficulty	0.694	0.306
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.693	0.307
T90 Sequelae of injuries of head	0.692	0.308
I09 Other rheumatic heart diseases	0.691	0.309
I06 Rheumatic aortic valve diseases	0.691	0.309
T92.2 Sequelae of fracture at wrist and hand level	0.689	0.311
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.689	0.311
T83.0 Mechanical complication of urinary (indwelling) catheter	0.688	0.312
I46.1 Sudden cardiac death, so described	0.688	0.312
E78.1 Pure hyperglyceridaemia	0.687	0.313
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.687	0.313
Z65 Problems related to other psychosocial circumstances	0.687	0.313
Z62 Other problems related to upbringing	0.687	0.313
Z61 Problems related to negative life events in childhood	0.687	0.313
Z55 Problems related to education and literacy	0.687	0.313
E40-E46 Malnutrition	0.685	0.315
T92.8 Sequelae of other specified injuries of upper limb	0.684	0.315
Z72.9 Problem related to lifestyle, unspecified	0.684	0.316
Z72.6 Gambling and betting	0.684	0.316
Z72.5 High-risk sexual behaviour	0.684	0.316
Z72.4 Inappropriate diet and eating habits	0.684	0.316
Z72.3 Lack of physical exercise	0.684	0.316
E53.9 Vitamin B deficiency, unspecified	0.684	0.316
E53.1 Pyridoxine deficiency	0.684	0.316
E53.0 Riboflavin deficiency	0.684	0.316
I33 Acute and subacute endocarditis	0.683	0.317
S06.8 Other intracranial injuries	0.682	0.317
S06.9 Intracranial injury, unspecified	0.682	0.318
S06.7 Intracranial injury with prolonged coma	0.682	0.318
S06.1 Traumatic cerebral oedema	0.682	0.318
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.682	0.318
S72 Fracture of femur	0.680	0.320
S06.5 Traumatic subdural haemorrhage	0.680	0.320
I08.9 Multiple valve disease, unspecified	0.679	0.320
E66.0 Obesity due to excess calories	0.679	0.321
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.677	0.323
Z75.8 Other problems related to medical facilities and other health care	0.676	0.324
R95-R99 Ill-defined and unknown causes of mortality	0.675	0.325
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.675	0.325
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.675	0.325
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.675	0.325
Z84 Family history of other conditions	0.675	0.325
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.673	0.327
I49 Other cardiac arrhythmias	0.673	0.327
Z63.5 Disruption of family by separation and divorce	0.673	0.327
I70.00 Atherosclerosis of aorta (without gangrene)	0.671	0.329
Z63.6 Dependent relative needing care at home	0.669	0.331
I67.9 Cerebrovascular disease, unspecified	0.669	0.331
W50-W64 Exposure to animate mechanical forces	0.666	0.334
T87 Complications peculiar to reattachment and amputation	0.666	0.334
I08.1 Disorders of both mitral and tricuspid valves	0.665	0.335
T80 Complications following infusion, transfusion and therapeutic injection	0.665	0.335
R43 Disturbances of smell and taste	0.664	0.335
E67 Other hyperalimentation	0.664	0.336
E68 Sequelae of hyperalimentation	0.664	0.336
Z72.2 Drug use	0.664	0.336
S12 Fracture of neck	0.661	0.339
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.660	0.340
E78.9 Disorder of lipoprotein metabolism, unspecified	0.660	0.340
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.659	0.341
T95 Sequelae of burns, corrosions and frostbite	0.658	0.341
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.658	0.341
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.658	0.341
I60.8 Other subarachnoid haemorrhage	0.658	0.342
T93 Sequelae of injuries of lower limb	0.658	0.342
W20-W49 Exposure to inanimate mechanical forces	0.658	0.342
I72.3 Aneurysm of iliac artery	0.657	0.342
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.657	0.343
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.656	0.343
E88.2 Lipomatosis, not elsewhere classified	0.655	0.345
Z59.8 Other problems relating to housing and economic circumstances	0.654	0.346
E78.8 Other disorders of lipoprotein metabolism	0.653	0.347
T23 Burn and corrosion of wrist and hand	0.651	0.349
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.651	0.349
T13 Other injuries of lower limb, level unspecified	0.651	0.349
S50 Superficial injury of forearm	0.650	0.350
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.647	0.353
Z63.4 Disappearance and death of family member	0.647	0.353
S00 Superficial injury of head	0.647	0.353
R01.2 Other cardiac sounds	0.646	0.354
Z57.5 Occupational exposure to toxic agents in other industries	0.646	0.354
Z57.8 Occupational exposure to other risk-factors	0.646	0.354
S02.1 Fracture of base of skull	0.645	0.354
I47.2 Ventricular tachycardia	0.646	0.354
T25 Burn and corrosion of ankle and foot	0.645	0.355
S05.5 Penetrating wound of eyeball with foreign body	0.645	0.355
T98 Sequelae of other and unspecified effects of external causes	0.644	0.355
T20.2 Burn of second degree of head and neck	0.643	0.357
I05 Rheumatic mitral valve diseases	0.642	0.358
Z75.9 Unspecified problem related to medical facilities and other health care	0.641	0.359
Z75.5 Holiday relief care	0.641	0.359
Z75.4 Unavailability and inaccessibility of other helping agencies	0.641	0.359
Z75.0 Medical services not available in home	0.641	0.359
R46 Symptoms and signs involving appearance and behaviour	0.641	0.359
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.638	0.361
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.638	0.362
I37 Pulmonary valve disorders	0.636	0.364
I60.4 Subarachnoid haemorrhage from basilar artery	0.636	0.364
E66.1 Drug-induced obesity	0.636	0.364
Z56.0 Unemployment, unspecified	0.635	0.365
I71.3 Abdominal aortic aneurysm, ruptured	0.634	0.365
I62 Other nontraumatic intracranial haemorrhage	0.634	0.366
S19 Other and unspecified injuries of neck	0.634	0.366
Z94.2 Lung transplant status	0.633	0.367
S06.4 Epidural haemorrhage	0.631	0.369
E73.9 Lactose intolerance, unspecified	0.631	0.369
S06.21 Diffuse brain injury (with open intracranial wound)	0.628	0.372
T92.4 Sequelae of injury of nerve of upper limb	0.628	0.372
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.628	0.372
Z63.9 Problem related to primary support group, unspecified	0.625	0.374
Z63.3 Absence of family member	0.625	0.374
Z63.2 Inadequate family support	0.625	0.374
Z63.1 Problems in relationship with parents and in-laws	0.625	0.374
V20-V29 Motorcycle rider injured in transport accident	0.625	0.375
E61 Deficiency of other nutrient elements	0.625	0.375
S14.1 Other and unspecified injuries of cervical spinal cord	0.623	0.377
S90 Superficial injury of ankle and foot	0.620	0.380
S17 Crushing injury of neck	0.619	0.380
S15 Injury of blood vessels at neck level	0.619	0.380
S11 Open wound of neck	0.619	0.380
S18 Traumatic amputation at neck level	0.619	0.380
S16 Injury of muscle and tendon at neck level	0.619	0.380
I61.8 Other intracerebral haemorrhage	0.619	0.381
Z94.1 Heart transplant status	0.619	0.381
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.618	0.382
R13 Dysphagia	0.618	0.382
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.618	0.382
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.617	0.382
S91 Open wound of ankle and foot	0.617	0.383
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.617	0.383
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.617	0.383
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.616	0.384
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.615	0.385
S70 Superficial injury of hip and thigh	0.615	0.385
S59 Other and unspecified injuries of forearm	0.614	0.386
X40-X49 Accidental poisoning by and exposure to noxious substances	0.614	0.386
I45.9 Conduction disorder, unspecified	0.613	0.387
M70-M79 Other soft tissue disorders	0.613	0.387
S00.8 Superficial injury of other parts of head	0.613	0.387
R19 Other symptoms and signs involving the digestive system and abdomen	0.612	0.388
X58-X59 Accidental exposure to other and unspecified factors	0.611	0.389
I08.2 Disorders of both aortic and tricuspid valves	0.610	0.390
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.610	0.390
I60.5 Subarachnoid haemorrhage from vertebral artery	0.610	0.390
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.610	0.390
R12 Heartburn	0.610	0.390
E51.2 Wernicke's encephalopathy	0.609	0.391
S02.10 Fracture of base of skull (closed)	0.608	0.392
M79 Other soft tissue disorders, not elsewhere classified	0.608	0.392
Z73.6 Limitation of activities due to disability	0.606	0.393
Z73.5 Social role conflict, not elsewhere classified	0.606	0.393
Z73.4 Inadequate social skills, not elsewhere classified	0.606	0.393
Z73.2 Lack of relaxation and leisure	0.606	0.393
Z73.1 Accentuation of personality traits	0.606	0.393
Z73.0 Burn-out	0.606	0.393
T79-T79 Certain early complications of trauma	0.605	0.395
E55 Vitamin D deficiency	0.604	0.396
T90.9 Sequelae of unspecified injury of head	0.603	0.397
S76 Injury of muscle and tendon at hip and thigh level	0.603	0.397
T36-T50 Poisoning by drugs, medicaments and biological substances	0.602	0.398
Z75.3 Unavailability and inaccessibility of health-care facilities	0.602	0.398
E88.9 Metabolic disorder, unspecified	0.601	0.399
E88.8 Other specified metabolic disorders	0.601	0.399
E88.3 Tumour lysis syndrome	0.601	0.399
E88.1 Lipodystrophy, not elsewhere classified	0.601	0.399
R40.2 Coma, unspecified	0.601	0.399
T14 Injury of unspecified body region	0.600	0.400
I23.8 Other current complications following acute myocardial infarction	0.599	0.401
S72.4 Fracture of lower end of femur	0.598	0.402
Chapter VIII Diseases of the ear and mastoid process	0.598	0.402
T66-T78 Other and unspecified effects of external causes	0.598	0.402
I72.9 Aneurysm of unspecified site	0.596	0.404
I72.6 Aneurysm and dissection of vertebral artery	0.596	0.404
I72.5 Aneurysm and dissection of other precerebral arteries	0.596	0.404
I72.2 Aneurysm of renal artery	0.596	0.404
I72.1 Aneurysm of artery of upper extremity	0.596	0.404
E65 Localised adiposity	0.596	0.404
T92.9 Sequelae of unspecified injury of upper limb	0.596	0.404
R03 Abnormal blood-pressure reading, without diagnosis	0.595	0.405
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.595	0.405
Z59.0 Homelessness	0.593	0.406
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.593	0.407
I49.0 Ventricular fibrillation and flutter	0.593	0.407
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.592	0.408
R40.1 Stupor	0.592	0.408
M79.0 Rheumatism, unspecified	0.592	0.408

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations