TreeWAS – Variant ID: rs9521632

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.999	0.001	0.000
I20.9 Angina pectoris, unspecified	0.997	0.003	0.000
I21 Acute myocardial infarction	0.995	0.005	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.993	0.007	0.000
I22 Subsequent myocardial infarction	0.983	0.017	0.000
I20.8 Other forms of angina pectoris	0.983	0.017	0.000
I21.9 Acute myocardial infarction, unspecified	0.976	0.024	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.962	0.038	0.000
Z95.1 Presence of aortocoronary bypass graft	0.960	0.040	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.952	0.048	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.930	0.070	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.917	0.083	0.000
I25.2 Old myocardial infarction	0.899	0.101	0.000
I24 Other acute ischaemic heart diseases	0.890	0.110	0.000
I20.0 Unstable angina	0.869	0.131	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.867	0.133	0.000
I21.4 Acute subendocardial myocardial infarction	0.841	0.159	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.828	0.172	0.000
I25.6 Silent myocardial ischaemia	0.825	0.175	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.793	0.207	0.000
I24.8 Other forms of acute ischaemic heart disease	0.782	0.218	0.000
I23 Certain current complications following acute myocardial infarction	0.780	0.220	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.763	0.237	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.755	0.245	0.000
Z95.4 Presence of other heart-valve replacement	0.747	0.253	0.000
I25.3 Aneurysm of heart	0.731	0.269	0.000
I25.4 Coronary artery aneurysm	0.717	0.283	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.713	0.287	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.703	0.297	0.000
I25.5 Ischaemic cardiomyopathy	0.702	0.298	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.662	0.338	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.645	0.354	0.000
I22.8 Subsequent myocardial infarction of other sites	0.634	0.366	0.000
I23.8 Other current complications following acute myocardial infarction	0.623	0.377	0.000
I24.1 Dressler's syndrome	0.572	0.428	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.559	0.440	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.559	0.440	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.559	0.440	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.559	0.440	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.559	0.440	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.559	0.440	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.559	0.440	0.000
Z95.0 Presence of cardiac pacemaker	0.555	0.445	0.000
Z95.3 Presence of xenogenic heart valve	0.527	0.472	0.000
Z95.2 Presence of prosthetic heart valve	0.450	0.550	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.304	0.696	0.000
I20.1 Angina pectoris with documented spasm	0.296	0.704	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.293	0.706	0.000
I73.9 Peripheral vascular disease, unspecified	0.093	0.907	0.000
Chapter IX Diseases of the circulatory system	0.087	0.913	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.086	0.914	0.000
I73 Other peripheral vascular diseases	0.085	0.915	0.000
I63.9 Cerebral infarction, unspecified	0.080	0.920	0.000
I60-I69 Cerebrovascular diseases	0.076	0.924	0.000
I77 Other disorders of arteries and arterioles	0.076	0.924	0.000
I63 Cerebral infarction	0.075	0.925	0.000
I61 Intracerebral haemorrhage	0.075	0.925	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.073	0.927	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.073	0.927	0.000
I78 Diseases of capillaries	0.072	0.928	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.067	0.933	0.000
I61.8 Other intracerebral haemorrhage	0.067	0.933	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.066	0.934	0.000
I77.1 Stricture of artery	0.065	0.935	0.000
I74 Arterial embolism and thrombosis	0.065	0.935	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.065	0.935	0.000
I77.8 Other specified disorders of arteries and arterioles	0.064	0.936	0.000
I95 Hypotension	0.064	0.936	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.062	0.937	0.000
I72 Other aneurysm	0.062	0.938	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.060	0.939	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.060	0.940	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.060	0.940	0.000
I95.8 Other hypotension	0.059	0.940	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.059	0.941	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.059	0.941	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.058	0.942	0.000
I78.8 Other diseases of capillaries	0.058	0.942	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.057	0.943	0.000
I00-I02 Acute rheumatic fever	0.057	0.943	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.056	0.944	0.000
I74.5 Embolism and thrombosis of iliac artery	0.056	0.944	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.055	0.945	0.000
I77.5 Necrosis of artery	0.054	0.946	0.000
I77.4 Coeliac artery compression syndrome	0.054	0.946	0.000
I77.3 Arterial fibromuscular dysplasia	0.054	0.946	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.054	0.946	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.054	0.946	0.000
I72.0 Aneurysm of carotid artery	0.054	0.946	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.053	0.947	0.000
I95.9 Hypotension, unspecified	0.053	0.947	0.000
I73.8 Other specified peripheral vascular diseases	0.053	0.947	0.000
I72.4 Aneurysm of artery of lower extremity	0.053	0.947	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.053	0.947	0.000
I78.9 Disease of capillaries, unspecified	0.052	0.948	0.000
I62 Other nontraumatic intracranial haemorrhage	0.051	0.949	0.000
I97.1 Other functional disturbances following cardiac surgery	0.050	0.950	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.050	0.950	0.000
I77.2 Rupture of artery	0.050	0.950	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.049	0.950	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.049	0.951	0.000
I78.1 Naevus, nonneoplastic	0.048	0.952	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.047	0.953	0.000
I70 Atherosclerosis	0.047	0.953	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.046	0.953	0.000
I79.1 Aortitis in diseases classified elsewhere	0.046	0.953	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.046	0.953	0.000
I65.1 Occlusion and stenosis of basilar artery	0.046	0.954	0.000
I72.9 Aneurysm of unspecified site	0.046	0.954	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.046	0.954	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.046	0.954	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.045	0.955	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.045	0.955	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.045	0.955	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.045	0.955	0.000
I74.8 Embolism and thrombosis of other arteries	0.044	0.955	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.044	0.956	0.000
I97.0 Postcardiotomy syndrome	0.044	0.956	0.000
I99 Other and unspecified disorders of circulatory system	0.044	0.956	0.000
I72.1 Aneurysm of artery of upper extremity	0.044	0.956	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.044	0.956	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.044	0.956	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.956	0.044
I95.1 Orthostatic hypotension	0.044	0.956	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.043	0.957	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.043	0.957	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.043	0.957	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.043	0.957	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.043	0.957	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.043	0.957	0.000
I68.0 Cerebral amyloid angiopathy	0.043	0.957	0.000
I65.2 Occlusion and stenosis of carotid artery	0.043	0.957	0.000
I77.0 Arteriovenous fistula, acquired	0.042	0.958	0.000
I72.8 Aneurysm of other specified arteries	0.042	0.958	0.000
I02 Rheumatic chorea	0.041	0.959	0.000
I01 Rheumatic fever with heart involvement	0.041	0.959	0.000
I63.8 Other cerebral infarction	0.041	0.959	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.041	0.959	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.041	0.959	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.041	0.959	0.000
I67 Other cerebrovascular diseases	0.040	0.960	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.040	0.960	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.039	0.961	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.038	0.961	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.038	0.961	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.038	0.961	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.038	0.961	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.038	0.962	0.000
I77.6 Arteritis, unspecified	0.038	0.962	0.000
I73.0 Raynaud's syndrome	0.038	0.962	0.000
I95.0 Idiopathic hypotension	0.038	0.962	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.038	0.962	0.000
I67.8 Other specified cerebrovascular diseases	0.037	0.963	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.036	0.964	0.000
I62.1 Nontraumatic extradural haemorrhage	0.035	0.965	0.000
I70.9 Generalised and unspecified atherosclerosis	0.035	0.965	0.000
I95.2 Hypotension due to drugs	0.035	0.965	0.000
I00 Rheumatic fever without mention of heart involvement	0.035	0.965	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.035	0.965	0.000
I70.8 Atherosclerosis of other arteries	0.035	0.965	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.035	0.965	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.035	0.965	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.034	0.965	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.034	0.966	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.034	0.966	0.000
I98.0 Cardiovascular syphilis	0.034	0.966	0.000
I72.2 Aneurysm of renal artery	0.032	0.968	0.000
I67.9 Cerebrovascular disease, unspecified	0.032	0.968	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.030	0.970	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.029	0.970	0.000
I01.8 Other acute rheumatic heart disease	0.029	0.970	0.000
I01.2 Acute rheumatic myocarditis	0.029	0.970	0.000
I01.1 Acute rheumatic endocarditis	0.029	0.970	0.000
I01.0 Acute rheumatic pericarditis	0.029	0.970	0.000
I02.9 Rheumatic chorea without heart involvement	0.029	0.970	0.000
I02.0 Rheumatic chorea with heart involvement	0.029	0.970	0.000
I70.1 Atherosclerosis of renal artery	0.029	0.970	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.029	0.971	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.029	0.971	0.000
I67.5 Moyamoya disease	0.029	0.971	0.000
I67.4 Hypertensive encephalopathy	0.029	0.971	0.000
I67.3 Progressive vascular leukoencephalopathy	0.029	0.971	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.029	0.971	0.000
I72.3 Aneurysm of iliac artery	0.028	0.972	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.027	0.972	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.027	0.973	0.000
I70.0 Atherosclerosis of aorta	0.027	0.973	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.026	0.973	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.025	0.974	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.025	0.975	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.023	0.977	0.000
I28 Other diseases of pulmonary vessels	0.023	0.977	0.000
I05-I09 Chronic rheumatic heart diseases	0.023	0.977	0.000
I10-I15 Hypertensive diseases	0.023	0.977	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.021	0.978	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.019	0.980	0.000
I71 Aortic aneurysm and dissection	0.019	0.981	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.019	0.981	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.018	0.982	0.000
I60 Subarachnoid haemorrhage	0.018	0.982	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.018	0.982	0.000
I06 Rheumatic aortic valve diseases	0.017	0.982	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.017	0.983	0.000
I28.8 Other specified diseases of pulmonary vessels	0.017	0.983	0.000
I67.1 Cerebral aneurysm, nonruptured	0.017	0.983	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.017	0.983	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.017	0.983	0.000
I28.1 Aneurysm of pulmonary artery	0.017	0.983	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.017	0.983	0.000
I13 Hypertensive heart and renal disease	0.016	0.984	0.000
I60.8 Other subarachnoid haemorrhage	0.016	0.984	0.000
O16 Unspecified maternal hypertension	0.015	0.985	0.000
E78.0 Pure hypercholesterolaemia	0.015	0.985	0.000
I11 Hypertensive heart disease	0.015	0.985	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.015	0.985	0.000
I71.0 Dissection of aorta [any part]	0.015	0.985	0.000
I12 Hypertensive renal disease	0.014	0.986	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.014	0.986	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.014	0.986	0.000
I06.0 Rheumatic aortic stenosis	0.014	0.986	0.000
I09 Other rheumatic heart diseases	0.014	0.986	0.000
I15 Secondary hypertension	0.014	0.986	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.013	0.987	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.013	0.987	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.013	0.987	0.000
I26 Pulmonary embolism	0.013	0.987	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.013	0.987	0.000
I06.8 Other rheumatic aortic valve diseases	0.013	0.987	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.013	0.987	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.013	0.987	0.000
I67.2 Cerebral atherosclerosis	0.013	0.987	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.012	0.987	0.000
I05 Rheumatic mitral valve diseases	0.013	0.987	0.000
I06.1 Rheumatic aortic insufficiency	0.012	0.987	0.000
I12.9 Hypertensive renal disease without renal failure	0.013	0.987	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.012	0.988	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.012	0.988	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.012	0.988	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.012	0.988	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.012	0.988	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.012	0.988	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.011	0.988	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.011	0.988	0.000
I15.9 Seconday hypertension, unspecified	0.011	0.989	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.011	0.989	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.011	0.989	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.011	0.989	0.000
I07 Rheumatic tricuspid valve diseases	0.011	0.989	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.011	0.989	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.010	0.990	0.000
I09.8 Other specified rheumatic heart diseases	0.010	0.990	0.000
I09.2 Chronic rheumatic pericarditis	0.010	0.990	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.010	0.990	0.000
I09.0 Rheumatic myocarditis	0.010	0.990	0.000
I05.0 Mitral stenosis	0.010	0.990	0.000
I15.8 Other secondary hypertension	0.010	0.990	0.000
I15.2 Hypertension secondary to endocrine disorders	0.010	0.990	0.000
I08 Multiple valve diseases	0.010	0.990	0.000
I05.9 Mitral valve disease, unspecified	0.010	0.990	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.009	0.990	0.000
E78.8 Other disorders of lipoprotein metabolism	0.009	0.991	0.000
I05.8 Other mitral valve diseases	0.009	0.991	0.000
I15.0 Renovascular hypertension	0.009	0.991	0.000
E78.4 Other hyperlipidaemia	0.009	0.991	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.991	0.009
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.008	0.991	0.000
I08.8 Other multiple valve diseases	0.009	0.991	0.000
Z73.3 Stress, not elsewhere classified	0.000	0.991	0.009
I08.9 Multiple valve disease, unspecified	0.008	0.992	0.000
E78.3 Hyperchylomicronaemia	0.008	0.992	0.000
I07.9 Tricuspid valve disease, unspecified	0.008	0.992	0.000
I07.8 Other tricuspid valve diseases	0.008	0.992	0.000
I07.2 Tricuspid stenosis with insufficiency	0.008	0.992	0.000
I07.0 Tricuspid stenosis	0.008	0.992	0.000
I05.1 Rheumatic mitral insufficiency	0.008	0.992	0.000
E78.6 Lipoprotein deficiency	0.008	0.992	0.000
E78.1 Pure hyperglyceridaemia	0.008	0.992	0.000
I09.9 Rheumatic heart disease, unspecified	0.007	0.992	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.007	0.993	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.007	0.993	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.007	0.993	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.007	0.993	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.006	0.994	0.000
I69 Sequelae of cerebrovascular disease	0.006	0.994	0.000
E78.5 Hyperlipidaemia, unspecified	0.006	0.994	0.000
L05.9 Pilonidal cyst without abscess	0.006	0.994	0.000
I05.2 Mitral stenosis with insufficiency	0.006	0.994	0.000
Z93.9 Artificial opening status, unspecified	0.000	0.994	0.006
I27 Other pulmonary heart diseases	0.006	0.994	0.000
Z93.5 Cystostomy status	0.000	0.994	0.006
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.006	0.994	0.000
Z93 Artificial opening status	0.000	0.994	0.006
I15.1 Hypertension secondary to other renal disorders	0.005	0.994	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.006	0.994	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.006	0.994	0.000
Y95 Nosocomial condition	0.005	0.995	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.000	0.995	0.005
I08.2 Disorders of both aortic and tricuspid valves	0.005	0.995	0.000
Z82.3 Family history of stroke	0.005	0.995	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.005	0.995	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
Z82.1 Family history of blindness and visual loss	0.005	0.995	0.000
Z93.8 Other artificial opening status	0.000	0.995	0.005
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.005	0.995	0.000
Z93.1 Gastrostomy status	0.000	0.995	0.005
S92.00 Fracture of calcaneus (closed)	0.005	0.995	0.000
Z93.2 Ileostomy status	0.000	0.995	0.005
I69.1 Sequelae of intracerebral haemorrhage	0.005	0.995	0.000
Z93.3 Colostomy status	0.000	0.995	0.005
I27.1 Kyphoscoliotic heart disease	0.004	0.995	0.000
O70.2 Third degree perineal laceration during delivery	0.000	0.996	0.004
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.004	0.996	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.004	0.996	0.000
B99 Other and unspecified infectious diseases	0.004	0.996	0.000
Y57.5 X-ray contrast media	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.004	0.996	0.000
Z82.2 Family history of deafness and hearing loss	0.004	0.996	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.996	0.004
M00.9 Pyogenic arthritis, unspecified	0.004	0.996	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.004	0.996	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.996	0.004
L05 Pilonidal cyst	0.004	0.996	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.004	0.996	0.000
L05.0 Pilonidal cyst with abscess	0.004	0.996	0.000
X23.9 Unspecified place	0.004	0.996	0.000
Y44.2 Anticoagulants	0.004	0.996	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.003	0.996	0.000
I69.3 Sequelae of cerebral infarction	0.003	0.996	0.000
S92.0 Fracture of calcaneus	0.003	0.997	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.003	0.997	0.000
I10 Essential (primary) hypertension	0.003	0.997	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.003	0.997	0.000
M00 Pyogenic arthritis	0.003	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
Q07.0 Arnold-Chiari syndrome	0.000	0.997	0.003
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.003	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.003	0.997	0.000
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.003	0.997	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.003	0.997	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
E78.2 Mixed hyperlipidaemia	0.003	0.997	0.001
I27.9 Pulmonary heart disease, unspecified	0.003	0.997	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.003	0.997	0.000
Z93.0 Tracheostomy status	0.000	0.997	0.003
S92.01 Fracture of calcaneus (open)	0.003	0.997	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.003	0.997	0.000
M00.0 Staphylococcal arthritis and polyarthritis	0.003	0.997	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.003	0.997	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.997	0.003
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.003	0.997	0.000
I27.2 Other secondary pulmonary hypertension	0.003	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.003	0.997	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.003	0.997	0.000
I50.1 Left ventricular failure	0.003	0.997	0.000
K25.4 Chronic or unspecified with haemorrhage	0.003	0.997	0.000
Y57.8 Other drugs and medicaments	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.003	0.997	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.003
Y57.7 Vitamins, not elsewhere classified	0.003	0.997	0.000
Y57.4 Pharmaceutical excipients	0.003	0.997	0.000
Y57.3 Alcohol deterrents	0.003	0.997	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
Y57.1 Lipotropic drugs	0.003	0.997	0.000
Y57.0 Appetite depressants [anorectics]	0.003	0.997	0.000
M00.86 Arthritis and polyarthritis due to other specified bacterial agents (Lower leg)	0.003	0.997	0.000
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)	0.003	0.997	0.000
Y57.6 Other diagnostic agents	0.003	0.997	0.000
M00.2 Other streptococcal arthritis and polyarthritis	0.002	0.997	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.002	0.997	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.001
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
O41.0 Oligohydramnios	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.002	0.998	0.000
M00.01 Staphylococcal arthritis and polyarthritis (Shoulder region)	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.000	0.998	0.002
N99.5 Malfunction of external stoma of urinary tract	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
Y42.2 Antithyroid drugs	0.002	0.998	0.000
Y45.5 4-Aminophenol derivatives	0.002	0.998	0.000
M00.09 Staphylococcal arthritis and polyarthritis (Site unspecified)	0.002	0.998	0.000
M00.08 Staphylococcal arthritis and polyarthritis (Other)	0.002	0.998	0.000
M00.07 Staphylococcal arthritis and polyarthritis (Ankle and foot)	0.002	0.998	0.000
M00.05 Staphylococcal arthritis and polyarthritis (Pelvic region and thigh)	0.002	0.998	0.000
M00.04 Staphylococcal arthritis and polyarthritis (Hand)	0.002	0.998	0.000
M00.03 Staphylococcal arthritis and polyarthritis (Forearm)	0.002	0.998	0.000
M00.02 Staphylococcal arthritis and polyarthritis (Upper arm)	0.002	0.998	0.000
M00.00 Staphylococcal arthritis and polyarthritis (Multiple sites)	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.002	0.998	0.000
Y98 Lifestyle-related condition	0.002	0.998	0.000
Y97 Environmental-pollution-related condition	0.002	0.998	0.000
Y96 Work-related condition	0.002	0.998	0.000
M00.89 Arthritis and polyarthritis due to other specified bacterial agents (Site unspecified)	0.002	0.998	0.000
M00.88 Arthritis and polyarthritis due to other specified bacterial agents (Other)	0.002	0.998	0.000
M00.87 Arthritis and polyarthritis due to other specified bacterial agents (Ankle and foot)	0.002	0.998	0.000
M00.85 Arthritis and polyarthritis due to other specified bacterial agents (Pelvic region and thigh)	0.002	0.998	0.000
M00.84 Arthritis and polyarthritis due to other specified bacterial agents (Hand)	0.002	0.998	0.000
M00.83 Arthritis and polyarthritis due to other specified bacterial agents (Forearm)	0.002	0.998	0.000
M00.82 Arthritis and polyarthritis due to other specified bacterial agents (Upper arm)	0.002	0.998	0.000
M00.81 Arthritis and polyarthritis due to other specified bacterial agents (Shoulder region)	0.002	0.998	0.000
M00.80 Arthritis and polyarthritis due to other specified bacterial agents (Multiple sites)	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.998	0.002
H70.9 Mastoiditis, unspecified	0.000	0.998	0.002
N99.1 Postprocedural urethral stricture	0.000	0.998	0.002
R27.0 Ataxia, unspecified	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
X23 Contact with hornets, wasps and bees	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
R26 Abnormalities of gait and mobility	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.002
Z73 Problems related to life-management difficulty	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
Y42.4 Oral contraceptives	0.002	0.998	0.000
O41 Other disorders of amniotic fluid and membranes	0.002	0.998	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.998	0.002
V49.9 Car occupant [any] injured in unspecified traffic accident	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
F11.1 Harmful use	0.002	0.998	0.000
Z13.3 Special screening examination for mental and behavioural disorders	0.002	0.998	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
M00.19 Pneumococcal arthritis and polyarthritis (Site unspecified)	0.002	0.998	0.000
M00.18 Pneumococcal arthritis and polyarthritis (Other)	0.002	0.998	0.000
M00.17 Pneumococcal arthritis and polyarthritis (Ankle and foot)	0.002	0.998	0.000
M00.16 Pneumococcal arthritis and polyarthritis (Lower leg)	0.002	0.998	0.000
M00.15 Pneumococcal arthritis and polyarthritis (Pelvic region and thigh)	0.002	0.998	0.000
M00.14 Pneumococcal arthritis and polyarthritis (Hand)	0.002	0.998	0.000
M00.13 Pneumococcal arthritis and polyarthritis (Forearm)	0.002	0.998	0.000
M00.12 Pneumococcal arthritis and polyarthritis (Upper arm)	0.002	0.998	0.000
M00.11 Pneumococcal arthritis and polyarthritis (Shoulder region)	0.002	0.998	0.000
M00.10 Pneumococcal arthritis and polyarthritis (Multiple sites)	0.002	0.998	0.000
M00.29 Other streptococcal arthritis and polyarthritis (Site unspecified)	0.002	0.998	0.000
M00.28 Other streptococcal arthritis and polyarthritis (Other)	0.002	0.998	0.000
M00.27 Other streptococcal arthritis and polyarthritis (Ankle and foot)	0.002	0.998	0.000
M00.26 Other streptococcal arthritis and polyarthritis (Lower leg)	0.002	0.998	0.000
M00.25 Other streptococcal arthritis and polyarthritis (Pelvic region and thigh)	0.002	0.998	0.000
M00.24 Other streptococcal arthritis and polyarthritis (Hand)	0.002	0.998	0.000
M00.23 Other streptococcal arthritis and polyarthritis (Forearm)	0.002	0.998	0.000
M00.22 Other streptococcal arthritis and polyarthritis (Upper arm)	0.002	0.998	0.000
M00.21 Other streptococcal arthritis and polyarthritis (Shoulder region)	0.002	0.998	0.000
M00.20 Other streptococcal arthritis and polyarthritis (Multiple sites)	0.002	0.998	0.000
F11.2 Dependence syndrome	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.002	0.998	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.998	0.002
V49.8 Car occupant [any] injured in other specified transport accidents	0.002	0.998	0.000
V49.3 Car occupant [any] injured in unspecified nontraffic accident	0.002	0.998	0.000
V49.2 Unspecified car occupant injured in collision with other and unspecified motor vehicles in nontraffic accident	0.002	0.998	0.000
V49.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident	0.002	0.998	0.000
V49.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.998	0.002
Q04.6 Congenital cerebral cysts	0.000	0.998	0.002
Q07.9 Congenital malformation of nervous system, unspecified	0.000	0.998	0.002
Q07.8 Other specified congenital malformations of nervous system	0.000	0.998	0.002
V40-V49 Car occupant injured in transport accident	0.002	0.998	0.000
O41.1 Infection of amniotic sac and membranes	0.002	0.998	0.000
Z73.6 Limitation of activities due to disability	0.000	0.998	0.002
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
Y90.8 Blood alcohol level of 240 mg/100 ml or more	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
Y90.9 Presence of alcohol in blood, level not specified	0.002	0.998	0.000
Y90.7 Blood alcohol level of 200-239 mg/100 ml	0.002	0.998	0.000
Y90.5 Blood alcohol level of 100-119 mg/100 ml	0.002	0.998	0.000
Y90.4 Blood alcohol level of 80-99 mg/100 ml	0.002	0.998	0.000
Y90.3 Blood alcohol level of 60-79 mg/100 ml	0.002	0.998	0.000
Y90.2 Blood alcohol level of 40-59 mg/100 ml	0.002	0.998	0.000
Y90.1 Blood alcohol level of 20-39 mg/100 ml	0.002	0.998	0.000
Y90.0 Blood alcohol level of less than 20 mg/100 ml	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
F11 Mental and behavioural disorders due to use of opioids	0.002	0.998	0.000
Y90.6 Blood alcohol level of 120-199 mg/100 ml	0.002	0.998	0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus	0.002	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations