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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7965087
log Bayes Factor = 10.4918
Chromosome 12   position 112,548,562  (GRCh37) Explore rs7965087 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.008 0.992
I25.2 Old myocardial infarction
0.000 0.008 0.992
I21.9 Acute myocardial infarction, unspecified
0.000 0.025 0.975
I22 Subsequent myocardial infarction
0.000 0.071 0.929
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.107 0.893
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.119 0.881
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.124 0.876
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.127 0.873
I21.4 Acute subendocardial myocardial infarction
0.000 0.147 0.853
Z95.4 Presence of other heart-valve replacement
0.000 0.148 0.852
I25.5 Ischaemic cardiomyopathy
0.000 0.162 0.837
Z95.3 Presence of xenogenic heart valve
0.000 0.172 0.828
Z95.1 Presence of aortocoronary bypass graft
0.000 0.206 0.794
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.207 0.793
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.213 0.787
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.251 0.749
I24 Other acute ischaemic heart diseases
0.000 0.256 0.744
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.261 0.738
I20 Angina pectoris
0.000 0.268 0.732
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I20.9 Angina pectoris, unspecified
0.000 0.289 0.711
I25.4 Coronary artery aneurysm
0.000 0.337 0.662
I25.3 Aneurysm of heart
0.000 0.345 0.655
Chapter IX Diseases of the circulatory system
0.000 0.346 0.654
Z95.2 Presence of prosthetic heart valve
0.000 0.349 0.651
I23 Certain current complications following acute myocardial infarction
0.000 0.353 0.647
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.353 0.647
I10-I15 Hypertensive diseases
0.000 0.361 0.639
I10 Essential (primary) hypertension
0.000 0.369 0.631
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.384 0.616
I05-I09 Chronic rheumatic heart diseases
0.000 0.385 0.615
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.388 0.612
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.400 0.600
I73 Other peripheral vascular diseases
0.000 0.400 0.600
I22.8 Subsequent myocardial infarction of other sites
0.000 0.407 0.593
I73.0 Raynaud's syndrome
0.000 0.427 0.573
I08 Multiple valve diseases
0.000 0.445 0.555
I24.8 Other forms of acute ischaemic heart disease
0.000 0.450 0.550
I73.9 Peripheral vascular disease, unspecified
0.000 0.457 0.543
I05 Rheumatic mitral valve diseases
0.000 0.459 0.541
I24.1 Dressler's syndrome
0.000 0.466 0.534
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.478 0.522
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.479 0.521
I12 Hypertensive renal disease
0.000 0.483 0.517
I08.0 Disorders of both mitral and aortic valves
0.000 0.505 0.495
I12.9 Hypertensive renal disease without renal failure
0.000 0.520 0.480
I71 Aortic aneurysm and dissection
0.000 0.526 0.474
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.529 0.471
I00-I02 Acute rheumatic fever
0.000 0.531 0.469
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.531 0.469
I07 Rheumatic tricuspid valve diseases
0.000 0.533 0.466
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.536 0.464
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.536 0.464
I13 Hypertensive heart and renal disease
0.000 0.541 0.458
I05.0 Mitral stenosis
0.000 0.542 0.458
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.546 0.454
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.548 0.452
Z95.0 Presence of cardiac pacemaker
0.000 0.550 0.450
I78 Diseases of capillaries
0.000 0.553 0.447
I74 Arterial embolism and thrombosis
0.000 0.555 0.445
I06 Rheumatic aortic valve diseases
0.000 0.559 0.441
I05.2 Mitral stenosis with insufficiency
0.000 0.563 0.437
I73.8 Other specified peripheral vascular diseases
0.000 0.569 0.430
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.569 0.430
I72 Other aneurysm
0.000 0.577 0.423
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.584 0.416
I15 Secondary hypertension
0.000 0.593 0.407
I05.1 Rheumatic mitral insufficiency
0.000 0.600 0.400
I11 Hypertensive heart disease
0.000 0.600 0.400
I09 Other rheumatic heart diseases
0.000 0.601 0.398
I08.9 Multiple valve disease, unspecified
0.000 0.602 0.398
I70 Atherosclerosis
0.000 0.604 0.396
I23.8 Other current complications following acute myocardial infarction
0.000 0.606 0.394
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.607 0.393
I05.8 Other mitral valve diseases
0.000 0.612 0.388
I05.9 Mitral valve disease, unspecified
0.000 0.618 0.382
I20.1 Angina pectoris with documented spasm
0.000 0.620 0.379
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.620 0.379
I74.5 Embolism and thrombosis of iliac artery
0.000 0.634 0.366
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.635 0.365
I07.1 Tricuspid insufficiency
0.000 0.640 0.360
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.650 0.350
I20.8 Other forms of angina pectoris
0.000 0.658 0.342
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.660 0.340
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.660 0.340
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.660 0.340
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.660 0.340
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.660 0.340
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.663 0.336
I02 Rheumatic chorea
0.000 0.664 0.336
I01 Rheumatic fever with heart involvement
0.000 0.664 0.336
I00 Rheumatic fever without mention of heart involvement
0.000 0.664 0.336
I07.9 Tricuspid valve disease, unspecified
0.000 0.665 0.335
I07.8 Other tricuspid valve diseases
0.000 0.665 0.335
I07.2 Tricuspid stenosis with insufficiency
0.000 0.665 0.335
I07.0 Tricuspid stenosis
0.000 0.665 0.335
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.671 0.329
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.671 0.329
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.671 0.329
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.671 0.329
I08.8 Other multiple valve diseases
0.000 0.671 0.328
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.676 0.324
I79.1 Aortitis in diseases classified elsewhere
0.000 0.676 0.324
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.676 0.324
I78.9 Disease of capillaries, unspecified
0.000 0.679 0.320
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.680 0.319
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.680 0.319
I78.8 Other diseases of capillaries
0.000 0.681 0.319
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.683 0.316
I06.8 Other rheumatic aortic valve diseases
0.000 0.683 0.316
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.683 0.316
I06.1 Rheumatic aortic insufficiency
0.000 0.683 0.316
I06.0 Rheumatic aortic stenosis
0.000 0.683 0.316
I72.3 Aneurysm of iliac artery
0.000 0.685 0.315
I72.8 Aneurysm of other specified arteries
0.000 0.686 0.314
I72.9 Aneurysm of unspecified site
0.000 0.696 0.304
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.696 0.304
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.696 0.304
I72.2 Aneurysm of renal artery
0.000 0.696 0.304
I72.1 Aneurysm of artery of upper extremity
0.000 0.696 0.304
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.698 0.302
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.703 0.297
I70.0 Atherosclerosis of aorta
0.000 0.706 0.294
I15.9 Seconday hypertension, unspecified
0.000 0.708 0.292
I15.8 Other secondary hypertension
0.000 0.708 0.292
I15.2 Hypertension secondary to endocrine disorders
0.000 0.708 0.292
I15.0 Renovascular hypertension
0.000 0.708 0.292
I72.4 Aneurysm of artery of lower extremity
0.000 0.710 0.290
I09.8 Other specified rheumatic heart diseases
0.000 0.714 0.286
I09.2 Chronic rheumatic pericarditis
0.000 0.714 0.286
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.714 0.286
I09.0 Rheumatic myocarditis
0.000 0.714 0.286
I70.1 Atherosclerosis of renal artery
0.000 0.716 0.284
I70.9 Generalised and unspecified atherosclerosis
0.000 0.716 0.284
I70.8 Atherosclerosis of other arteries
0.000 0.716 0.284
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.717 0.283
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.717 0.282
I72.0 Aneurysm of carotid artery
0.000 0.723 0.277
I99 Other and unspecified disorders of circulatory system
0.000 0.728 0.271
I74.8 Embolism and thrombosis of other arteries
0.000 0.730 0.270
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.737 0.263
I97.1 Other functional disturbances following cardiac surgery
0.000 0.745 0.255
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.754 0.246
I09.9 Rheumatic heart disease, unspecified
0.000 0.757 0.243
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.759 0.241
I01.8 Other acute rheumatic heart disease
0.000 0.759 0.241
I01.2 Acute rheumatic myocarditis
0.000 0.759 0.241
I01.1 Acute rheumatic endocarditis
0.000 0.759 0.241
I01.0 Acute rheumatic pericarditis
0.000 0.759 0.241
I02.9 Rheumatic chorea without heart involvement
0.000 0.759 0.241
I02.0 Rheumatic chorea with heart involvement
0.000 0.759 0.241
I15.1 Hypertension secondary to other renal disorders
0.000 0.759 0.241
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.761 0.239
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.763 0.237
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.766 0.234
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.767 0.233
I78.1 Naevus, nonneoplastic
0.000 0.772 0.228
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.775 0.225
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.779 0.221
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.783 0.217
I97.0 Postcardiotomy syndrome
0.000 0.783 0.217
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.789 0.211
I71.0 Dissection of aorta [any part]
0.001 0.793 0.207
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.796 0.204
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.796 0.204
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.796 0.204
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.796 0.204
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.796 0.204
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.796 0.204
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.805 0.195
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.819 0.181
I77 Other disorders of arteries and arterioles
0.000 0.820 0.180
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.823 0.176
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.823 0.176
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.823 0.176
I98.0 Cardiovascular syphilis
0.000 0.823 0.176
I12.0 Hypertensive renal disease with renal failure
0.000 0.827 0.173
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.839 0.161
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.839 0.161
I28 Other diseases of pulmonary vessels
0.000 0.840 0.159
I20.0 Unstable angina
0.000 0.843 0.157
I30-I52 Other forms of heart disease
0.000 0.844 0.156
I35 Nonrheumatic aortic valve disorders
0.000 0.857 0.143
I35.0 Aortic (valve) stenosis
0.000 0.861 0.139
I77.6 Arteritis, unspecified
0.000 0.865 0.135
I44 Atrioventricular and left bundle-branch block
0.000 0.865 0.135
I36 Nonrheumatic tricuspid valve disorders
0.000 0.866 0.134
I49 Other cardiac arrhythmias
0.000 0.868 0.132
I77.5 Necrosis of artery
0.000 0.871 0.129
I77.4 Coeliac artery compression syndrome
0.000 0.871 0.129
I77.3 Arterial fibromuscular dysplasia
0.000 0.871 0.129
I77.2 Rupture of artery
0.000 0.871 0.129
I49.3 Ventricular premature depolarisation
0.000 0.872 0.128
M22 Disorders of patella
0.128 0.872 0.000
I42 Cardiomyopathy
0.000 0.872 0.128
I47 Paroxysmal tachycardia
0.000 0.873 0.127
M20-M25 Other joint disorders
0.127 0.873 0.000
M24 Other specific joint derangements
0.127 0.873 0.000
I26 Pulmonary embolism
0.000 0.874 0.126
M22.4 Chondromalacia patellae
0.125 0.875 0.000
I44.7 Left bundle-branch block, unspecified
0.000 0.875 0.125
M24.2 Disorder of ligament
0.122 0.878 0.000
M25 Other joint disorders, not elsewhere classified
0.122 0.878 0.000
I49.4 Other and unspecified premature depolarisation
0.000 0.880 0.120
I47.2 Ventricular tachycardia
0.000 0.880 0.120
M24.0 Loose body in joint
0.119 0.881 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.882 0.118
M24.23 Disorder of ligament (Forearm)
0.116 0.884 0.000
I37 Pulmonary valve disorders
0.000 0.885 0.115
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.885 0.114
I28.1 Aneurysm of pulmonary artery
0.000 0.885 0.114
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.885 0.114
M25.3 Other instability of joint
0.112 0.888 0.000
I52 Other heart disorders in diseases classified elsewhere
0.000 0.888 0.112
I48 Atrial fibrillation and flutter
0.000 0.888 0.112
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.888 0.112
I41 Myocarditis in diseases classified elsewhere
0.000 0.888 0.112
I40 Acute myocarditis
0.000 0.888 0.112
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.888 0.112
I32 Pericarditis in diseases classified elsewhere
0.000 0.888 0.112
M20 Acquired deformities of fingers and toes
0.111 0.889 0.000
I44.6 Other and unspecified fascicular block
0.000 0.889 0.111
I42.0 Dilated cardiomyopathy
0.000 0.890 0.110
M25.0 Haemarthrosis
0.109 0.891 0.000
M22.3 Other derangements of patella
0.109 0.891 0.000
M20.0 Deformity of finger(s)
0.107 0.893 0.000
I35.9 Aortic valve disorder, unspecified
0.000 0.893 0.107
M24.02 Loose body in joint (Upper arm)
0.106 0.894 0.000
I77.0 Arteriovenous fistula, acquired
0.000 0.894 0.105
M25.4 Effusion of joint
0.105 0.895 0.000
I42.9 Cardiomyopathy, unspecified
0.000 0.895 0.105
I28.8 Other specified diseases of pulmonary vessels
0.000 0.896 0.104
I49.0 Ventricular fibrillation and flutter
0.000 0.896 0.104
M25.8 Other specified joint disorders
0.103 0.897 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.102 0.898 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.898 0.102
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.899 0.101
M22.8 Other disorders of patella
0.101 0.899 0.000
I77.1 Stricture of artery
0.000 0.899 0.101
M34 Systemic sclerosis
0.101 0.899 0.000
M25.06 Haemarthrosis (Lower leg)
0.100 0.900 0.000
M21 Other acquired deformities of limbs
0.100 0.900 0.000
M31 Other necrotising vasculopathies
0.098 0.901 0.000
M20.5 Other deformities of toe(s) (acquired)
0.098 0.902 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.902 0.098
I77.8 Other specified disorders of arteries and arterioles
0.000 0.902 0.097
I44.5 Left posterior fascicular block
0.000 0.903 0.097
I44.4 Left anterior fascicular block
0.000 0.903 0.097
M25.31 Other instability of joint (Shoulder region)
0.097 0.903 0.000
I35.8 Other aortic valve disorders
0.000 0.903 0.097
I44.3 Other and unspecified atrioventricular block
0.000 0.903 0.097
I44.1 Atrioventricular block, second degree
0.000 0.903 0.097
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.904 0.096
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.904 0.096
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.904 0.096
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.904 0.096
I33 Acute and subacute endocarditis
0.000 0.904 0.096
M22.2 Patellofemoral disorders
0.096 0.904 0.000
I47.0 Reentry ventricular arrhythmia
0.000 0.904 0.096
M24.28 Disorder of ligament (Other)
0.095 0.905 0.000
M24.07 Loose body in joint (Ankle and foot)
0.095 0.905 0.000
I49.2 Junctional premature depolarisation
0.000 0.905 0.095
M24.26 Disorder of ligament (Lower leg)
0.095 0.905 0.000
M25.42 Effusion of joint (Upper arm)
0.095 0.905 0.000
M24.03 Loose body in joint (Forearm)
0.093 0.906 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.093 0.907 0.000
M24.21 Disorder of ligament (Shoulder region)
0.093 0.907 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.093 0.907 0.000
M22.1 Recurrent subluxation of patella
0.092 0.908 0.000
M22.9 Disorder of patella, unspecified
0.092 0.908 0.000
M22.0 Recurrent dislocation of patella
0.092 0.908 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.908 0.092
M25.9 Joint disorder, unspecified
0.092 0.908 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.908 0.092
I42.5 Other restrictive cardiomyopathy
0.000 0.908 0.092
I42.4 Endocardial fibroelastosis
0.000 0.908 0.092
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.908 0.092
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.091 0.909 0.000
M24.9 Joint derangement, unspecified
0.091 0.909 0.000
M24.7 Protrusio acetabuli
0.091 0.909 0.000
M24.6 Ankylosis of joint
0.091 0.909 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.091 0.909 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.909 0.090
M24.27 Disorder of ligament (Ankle and foot)
0.091 0.909 0.000
M25.36 Other instability of joint (Lower leg)
0.090 0.910 0.000
I44.0 Atrioventricular block, first degree
0.000 0.910 0.090
M24.5 Contracture of joint
0.090 0.910 0.000
M33 Dermatopolymyositis
0.089 0.911 0.000
M25.37 Other instability of joint (Ankle and foot)
0.089 0.911 0.000
M24.01 Loose body in joint (Shoulder region)
0.088 0.912 0.000
M32 Systemic lupus erythematosus
0.088 0.912 0.000
M24.29 Disorder of ligament (Site unspecified)
0.088 0.912 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.088 0.912 0.000
M24.22 Disorder of ligament (Upper arm)
0.088 0.912 0.000
M24.20 Disorder of ligament (Multiple sites)
0.088 0.912 0.000
M25.2 Flail joint
0.088 0.912 0.000
M25.1 Fistula of joint
0.088 0.912 0.000
M25.88 Other specified joint disorders (Other)
0.087 0.913 0.000
M31.6 Other giant cell arteritis
0.087 0.913 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.914 0.086
I37.1 Pulmonary valve insufficiency
0.000 0.914 0.086
M24.09 Loose body in joint (Site unspecified)
0.085 0.915 0.000
M24.08 Loose body in joint (Other)
0.085 0.915 0.000
M24.06 Loose body in joint-Lower leg
0.085 0.915 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.085 0.915 0.000
M24.04 Loose body in joint (Hand)
0.085 0.915 0.000
M24.00 Loose body in joint (Multiple sites)
0.085 0.915 0.000
I30 Acute pericarditis
0.000 0.915 0.085
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.916 0.083
M24.24 Disorder of ligament (Hand)
0.083 0.917 0.000
I37.9 Pulmonary valve disorder, unspecified
0.000 0.917 0.083
I37.8 Other pulmonary valve disorders
0.000 0.917 0.083
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.917 0.083
I37.0 Pulmonary valve stenosis
0.000 0.917 0.083
I35.1 Aortic (valve) insufficiency
0.000 0.917 0.083
M25.34 Other instability of joint (Hand)
0.082 0.917 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.082 0.918 0.000
M34.9 Systemic sclerosis, unspecified
0.082 0.918 0.000
M25.7 Osteophyte
0.082 0.918 0.000
M30 Polyarteritis nodosa and related conditions
0.081 0.918 0.000
I42.2 Other hypertrophic cardiomyopathy
0.000 0.919 0.081
M25.39 Other instability of joint (Site unspecified)
0.081 0.919 0.000
M25.38 Other instability of joint (Other)
0.081 0.919 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.081 0.919 0.000
M25.33 Other instability of joint (Forearm)
0.081 0.919 0.000
M25.32 Other instability of joint (Upper arm)
0.081 0.919 0.000
M25.30 Other instability of joint (Multiple sites)
0.081 0.919 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.919 0.080
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.919 0.080
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.919 0.080
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.919 0.080
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.919 0.080
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.919 0.080
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.919 0.080
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.919 0.080
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.919 0.080
I40.9 Acute myocarditis, unspecified
0.000 0.919 0.080
I40.8 Other acute myocarditis
0.000 0.919 0.080
I40.1 Isolated myocarditis
0.000 0.919 0.080
I40.0 Infective myocarditis
0.000 0.919 0.080
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.919 0.080
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.919 0.080
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.919 0.080
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.919 0.080
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.919 0.080
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.919 0.080
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.919 0.080
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.919 0.080
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.919 0.080
I48.4 Atypical atrial flutter
0.000 0.919 0.080
I48.3 Typical atrial flutter
0.000 0.919 0.080
I48.2 Chronic atrial fibrillation
0.000 0.919 0.080
I48.1 Persistent atrial fibrillation
0.000 0.919 0.080
I48.0 Paroxysmal atrial fibrillation
0.000 0.919 0.080
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.919 0.080
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.919 0.080
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.919 0.080
I27 Other pulmonary heart diseases
0.000 0.920 0.080
I49.1 Atrial premature depolarisation
0.000 0.920 0.080
M21.0 Valgus deformity, not elsewhere classified
0.080 0.920 0.000
I42.8 Other cardiomyopathies
0.000 0.920 0.079
M21.7 Unequal limb length (acquired)
0.079 0.920 0.000
M25.86 Other specified joint disorders (Lower leg)
0.079 0.921 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.079 0.921 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.079 0.921 0.000
M25.09 Haemarthrosis (Site unspecified)
0.078 0.921 0.000
M25.08 Haemarthrosis (Other)
0.078 0.921 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.078 0.921 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.078 0.921 0.000
M25.04 Haemarthrosis (Hand)
0.078 0.921 0.000
M25.03 Haemarthrosis (Forearm)
0.078 0.921 0.000
M25.02 Haemarthrosis (Upper arm)
0.078 0.921 0.000
M25.01 Haemarthrosis (Shoulder region)
0.078 0.921 0.000
M25.00 Haemarthrosis (Multiple sites)
0.078 0.921 0.000
I38 Endocarditis, valve unspecified
0.000 0.921 0.078
I85 Oesophageal varices
0.000 0.922 0.078
M24.4 Recurrent dislocation and subluxation of joint
0.078 0.922 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.077 0.923 0.000
M21.3 Wrist or foot drop (acquired)
0.077 0.923 0.000
M25.47 Effusion of joint (Ankle and foot)
0.077 0.923 0.000
I42.6 Alcoholic cardiomyopathy
0.000 0.924 0.076
M21.6 Other acquired deformities of ankle and foot
0.076 0.924 0.000
M20.2 Hallux rigidus
0.076 0.924 0.000
M24.1 Other articular cartilage disorders
0.076 0.924 0.000
M25.49 Effusion of joint (Site unspecified)
0.075 0.924 0.000
M25.48 Effusion of joint (Other)
0.075 0.924 0.000
M25.44 Effusion of joint (Hand)
0.075 0.924 0.000
M25.43 Effusion of joint (Forearm)
0.075 0.924 0.000
M25.41 Effusion of joint (Shoulder region)
0.075 0.924 0.000
M25.40 Effusion of joint (Multiple sites)
0.075 0.924 0.000
I31 Other diseases of pericardium
0.000 0.924 0.075
M34.8 Other forms of systemic sclerosis
0.075 0.925 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.074 0.926 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.074 0.926 0.000
M25.83 Other specified joint disorders (Forearm)
0.074 0.926 0.000
M25.82 Other specified joint disorders (Upper arm)
0.074 0.926 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.074 0.926 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.074 0.926 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.074 0.926 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.074 0.926 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.074 0.926 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.074 0.926 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.074 0.926 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.074 0.926 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.074 0.926 0.000
M25.84 Other specified joint disorders (Hand)
0.073 0.927 0.000
M25.74 Osteophyte (Hand)
0.073 0.927 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.072 0.927 0.000
M34.0 Progressive systemic sclerosis
0.072 0.927 0.000
I85.0 Oesophageal varices with bleeding
0.000 0.928 0.072
M21.9 Acquired deformity of limb, unspecified
0.072 0.928 0.000
M21.8 Other specified acquired deformities of limbs
0.072 0.928 0.000
M31.9 Necrotising vasculopathy, unspecified
0.071 0.929 0.000
M31.8 Other specified necrotising vasculopathies
0.071 0.929 0.000
M31.7 Microscopic polyangiitis
0.071 0.929 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.071 0.929 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.071 0.929 0.000
M31.2 Lethal midline granuloma
0.071 0.929 0.000
M31.1 Thrombotic microangiopathy
0.071 0.929 0.000
M31.0 Hypersensitivity angiitis
0.071 0.929 0.000
M25.78 Osteophyte (Other)
0.071 0.929 0.000
M34.1 CR(E)ST syndrome
0.070 0.929 0.000
M25.72 Osteophyte (Upper arm)
0.070 0.930 0.000
M21.4 Flat foot [pes planus] (acquired)
0.069 0.931 0.000
I33.9 Acute endocarditis, unspecified
0.000 0.931 0.069
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.069 0.931 0.000
I46 Cardiac arrest
0.000 0.932 0.068
M21.2 Flexion deformity
0.068 0.932 0.000
I50 Heart failure
0.000 0.932 0.068
M25.46 Effusion of joint (Lower leg)
0.067 0.932 0.000
I44.2 Atrioventricular block, complete
0.000 0.933 0.067
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.067 0.933 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.067 0.933 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.067 0.933 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.067 0.933 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.067 0.933 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.067 0.933 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.067 0.933 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.067 0.933 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.067 0.933 0.000
I86 Varicose veins of other sites
0.000 0.933 0.067
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.066 0.934 0.000
M21.1 Varus deformity, not elsewhere classified
0.066 0.934 0.000
M22.10 Recurrent subluxation of patella, unspecified knee
0.066 0.934 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.066 0.934 0.000
M25.98 Joint disorder, unspecified (Other)
0.066 0.934 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.066 0.934 0.000
M25.94 Joint disorder, unspecified (Hand)
0.066 0.934 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.066 0.934 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.066 0.934 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.066 0.934 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.066 0.934 0.000
I88 Nonspecific lymphadenitis
0.000 0.934 0.066
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.065 0.934 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.065 0.934 0.000
M36.3 Arthropathy in other blood disorders
0.065 0.934 0.000
M36.2 Haemophilic arthropathy
0.065 0.934 0.000
M36.1 Arthropathy in neoplastic disease
0.065 0.934 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.065 0.934 0.000
M24.69 Ankylosis of joint (Site unspecified)
0.065 0.934 0.000
M24.68 Ankylosis of joint (Other)
0.065 0.934 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.065 0.934 0.000
M24.66 Ankylosis of joint (Lower leg)
0.065 0.934 0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)
0.065 0.934 0.000
M24.64 Ankylosis of joint (Hand)
0.065 0.934 0.000
M24.63 Ankylosis of joint (Forearm)
0.065 0.934 0.000
M24.62 Ankylosis of joint (Upper arm)
0.065 0.934 0.000
M24.61 Ankylosis of joint (Shoulder region)
0.065 0.934 0.000
M24.60 Ankylosis of joint (Multiple sites)
0.065 0.934 0.000
M24.79 Protrusio acetabuli-Site unspec
0.065 0.934 0.000
M24.78 Protrusio acetabuli-Other
0.065 0.934 0.000
M24.77 Protrusio acetabuli-Ankle/foot
0.065 0.934 0.000
M24.76 Protrusio acetabuli-Lower leg
0.065 0.934 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.065 0.934 0.000
M24.74 Protrusio acetabuli-Hand
0.065 0.934 0.000
M24.73 Protrusio acetabuli-Forearm
0.065 0.934 0.000
M24.72 Protrusio acetabuli-Upper arm
0.065 0.934 0.000
M24.71 Protrusio acetabuli-Shldr region
0.065 0.934 0.000
M24.70 Protrusio acetabuli-Mult sites
0.065 0.934 0.000
M24.99 Joint derangement, unspecified (Site unspecified)
0.065 0.934 0.000
M24.98 Joint derangement, unspecified (Other)
0.065 0.934 0.000
M24.97 Joint derangement, unspecified (Ankle and foot)
0.065 0.934 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.065 0.934 0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)
0.065 0.934 0.000
M24.94 Joint derangement, unspecified (Hand)
0.065 0.934 0.000
M24.93 Joint derangement, unspecified (Forearm)
0.065 0.934 0.000
M24.92 Joint derangement, unspecified (Upper arm)
0.065 0.934 0.000
M24.91 Joint derangement, unspecified (Shoulder region)
0.065 0.934 0.000
M24.90 Joint derangement, unspecified (Multiple sites)
0.065 0.934 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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