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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0142
log Bayes Factor = 295.63
contains 12 variants:
rs7418032
lBF = 19.741
Chr 1 : 195,229,043
rs114239030
lBF = 16.236
Chr 3 : 84,228,854
rs56890907
lBF = 17.462
Chr 3 : 196,673,831
rs116775899
lBF = 12.205
Chr 5 : 76,143,246
rs72799335
lBF = 16.564
Chr 5 : 107,878,176
rs6934690
lBF = 14.595
Chr 6 : 54,054,686
rs116955587
lBF = 13.389
Chr 6 : 97,757,667
rs17235038
lBF = 16.917
Chr10 : 115,614,740
rs5744807
lBF = 13.117
Chr12 : 133,243,621
rs116971837
lBF = 14.357
Chr17 : 8,680,917
rs11652121
lBF = 15.481
Chr17 : 28,532,332
rs118118953
lBF = 13.937
Chr22 : 34,002,123
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.2 Old myocardial infarction
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I95.9 Hypotension, unspecified
1.000 0.000 0.000
N17.9 Acute renal failure, unspecified
1.000 0.000 0.000
N18.9 Chronic renal failure, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I22 Subsequent myocardial infarction
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
I51 Complications and ill-defined descriptions of heart disease
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
N18 Chronic renal failure
1.000 0.000 0.000
A30-A49 Other bacterial diseases
1.000 0.000 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I35 Nonrheumatic aortic valve disorders
1.000 0.000 0.000
G90-G99 Other disorders of the nervous system
1.000 0.000 0.000
H65-H75 Diseases of middle ear and mastoid
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
Chapter VIII Diseases of the ear and mastoid process
1.000 0.000 0.000
E87.6 Hypokalaemia
1.000 0.000 0.000
I22.9 Subsequent myocardial infarction of unspecified site
1.000 0.000 0.000
J90-J94 Other diseases of pleura
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
I50.0 Congestive heart failure
1.000 0.000 0.000
I95 Hypotension
1.000 0.000 0.000
N17 Acute renal failure
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
1.000 0.000 0.000
I95-I99 Other and unspecified disorders of the circulatory system
1.000 0.000 0.000
D68 Other coagulation defects
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
1.000 0.000 0.000
I42 Cardiomyopathy
1.000 0.000 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
1.000 0.000 0.000
N18.5 Chronic kidney disease, stage 5
1.000 0.000 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
1.000 0.000 0.000
D69 Purpura and other haemorrhagic conditions
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
M23 Internal derangement of knee
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
J93 Pneumothorax
1.000 0.000 0.000
M19 Other arthrosis
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
0.999 0.001 0.000
E10.1 With ketoacidosis
0.999 0.001 0.000
I20.0 Unstable angina
0.999 0.001 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.999 0.001 0.000
S60-S69 Injuries to the wrist and hand
0.999 0.001 0.000
I35.0 Aortic (valve) stenosis
0.999 0.001 0.000
D80-D89 Certain disorders involving the immune mechanism
0.999 0.001 0.000
M19.0 Primary arthrosis of other joints
0.999 0.001 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.999 0.001 0.000
Y52 Agents primarily affecting the cardiovascular system
0.999 0.001 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
D69.6 Thrombocytopenia, unspecified
0.999 0.001 0.000
M23.3 Other meniscus derangements
0.999 0.001 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
B35-B49 Mycoses
0.999 0.001 0.000
W00-W19 Falls
0.999 0.001 0.000
E87.7 Fluid overload
0.999 0.001 0.000
F30-F39 Mood [affective] disorders
0.998 0.002 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.998 0.002 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.998 0.002 0.000
M10 Gout
0.998 0.002 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.998 0.002 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.998 0.002 0.000
J93.9 Pneumothorax, unspecified
0.998 0.002 0.000
H66 Suppurative and unspecified otitis media
0.998 0.002 0.000
J95-J99 Other diseases of the respiratory system
0.998 0.002 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.998 0.002 0.000
D86 Sarcoidosis
0.998 0.002 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.998 0.002 0.000
A49 Bacterial infection of unspecified site
0.998 0.002 0.000
G93 Other disorders of brain
0.998 0.002 0.000
E87.5 Hyperkalaemia
0.998 0.002 0.000
E10.9 Without complications
0.998 0.002 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.998 0.002 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.997 0.003 0.000
A41 Other septicaemia
0.997 0.003 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.997 0.003 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.997 0.003 0.000
S70-S79 Injuries to the hip and thigh
0.997 0.003 0.000
I51.7 Cardiomegaly
0.997 0.003 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.997 0.003 0.000
M10.9 Gout, unspecified
0.997 0.003 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.997 0.003 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.997 0.003 0.000
M84 Disorders of continuity of bone
0.997 0.003 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.997 0.003 0.000
I10-I15 Hypertensive diseases
0.997 0.003 0.000
I51.8 Other ill-defined heart diseases
0.996 0.004 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.996 0.004 0.000
I62 Other nontraumatic intracranial haemorrhage
0.996 0.004 0.000
M24 Other specific joint derangements
0.996 0.004 0.000
C71 Malignant neoplasm of brain
0.996 0.004 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.995 0.005 0.000
E10.5 With peripheral circulatory complications
0.995 0.005 0.000
G40-G47 Episodic and paroxysmal disorders
0.995 0.005 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.995 0.005 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.995 0.005 0.000
E11 Non-insulin-dependent diabetes mellitus
0.995 0.005 0.000
I12 Hypertensive renal disease
0.994 0.006 0.000
N18.0 End-stage renal disease
0.994 0.006 0.000
G62 Other polyneuropathies
0.994 0.006 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.993 0.007 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.993 0.007 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.993 0.007 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.993 0.007 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.993 0.007 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.993 0.007 0.000
M81 Osteoporosis without pathological fracture
0.993 0.007 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.992 0.008 0.000
M10.96 Gout, unspecified (Lower leg)
0.992 0.008 0.000
S50-S59 Injuries to the elbow and forearm
0.992 0.008 0.000
M35 Other systemic involvement of connective tissue
0.992 0.008 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.992 0.008 0.000
I51.9 Heart disease, unspecified
0.991 0.009 0.000
Z73 Problems related to life-management difficulty
0.991 0.009 0.000
E10.3 With ophthalmic complications
0.991 0.009 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.991 0.009 0.000
E83 Disorders of mineral metabolism
0.990 0.010 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.990 0.010 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.990 0.010 0.000
Q23 Congenital malformations of aortic and mitral valves
0.990 0.010 0.000
Z63 Other problems related to primary support group, including family circumstances
0.990 0.010 0.000
J90 Pleural effusion, not elsewhere classified
0.990 0.010 0.000
H66.9 Otitis media, unspecified
0.990 0.010 0.000
N18.4 Chronic kidney disease, stage 4
0.989 0.011 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.989 0.011 0.000
I31 Other diseases of pericardium
0.989 0.011 0.000
N05 Unspecified nephritic syndrome
0.989 0.011 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.989 0.011 0.000
L60-L75 Disorders of skin appendages
0.988 0.012 0.000
D68.8 Other specified coagulation defects
0.988 0.012 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.988 0.012 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.988 0.012 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.988 0.012 0.000
M70.2 Olecranon bursitis
0.987 0.013 0.000
I67 Other cerebrovascular diseases
0.987 0.013 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.986 0.014 0.000
M25.8 Other specified joint disorders
0.986 0.014 0.000
T91 Sequelae of injuries of neck and trunk
0.986 0.014 0.000
O80-O84 Delivery
0.986 0.014 0.000
S06 Intracranial injury
0.986 0.014 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.986 0.014 0.000
G51 Facial nerve disorders
0.986 0.014 0.000
I72 Other aneurysm
0.986 0.014 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.986 0.014 0.000
B15-B19 Viral hepatitis
0.985 0.015 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.985 0.015 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.985 0.015 0.000
R01 Cardiac murmurs and other cardiac sounds
0.985 0.015 0.000
R02 Gangrene, not elsewhere classified
0.985 0.015 0.000
M24.2 Disorder of ligament
0.984 0.016 0.000
O20 Haemorrhage in early pregnancy
0.984 0.016 0.000
E10.4 With neurological complications
0.984 0.016 0.000
E11.2 With renal complications
0.984 0.016 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.984 0.016 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.983 0.017 0.000
I35.1 Aortic (valve) insufficiency
0.983 0.017 0.000
R73 Elevated blood glucose level
0.983 0.017 0.000
I25.5 Ischaemic cardiomyopathy
0.983 0.017 0.000
R03.1 Nonspecific low blood-pressure reading
0.983 0.017 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.982 0.018 0.000
L89 Decubitus ulcer
0.982 0.018 0.000
G83 Other paralytic syndromes
0.982 0.018 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.982 0.018 0.000
Q23.1 Congenital insufficiency of aortic valve
0.981 0.019 0.000
M21 Other acquired deformities of limbs
0.981 0.019 0.000
O44 Placenta praevia
0.981 0.019 0.000
M70.22 Olecranon bursitis-Upper arm
0.980 0.020 0.000
R73.0 Abnormal glucose tolerance test
0.980 0.020 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.980 0.020 0.000
I67.8 Other specified cerebrovascular diseases
0.980 0.020 0.000
F60-F69 Disorders of adult personality and behaviour
0.979 0.021 0.000
G90 Disorders of autonomic nervous system
0.979 0.021 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.978 0.022 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.977 0.023 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.977 0.023 0.000
I31.3 Pericardial effusion (noninflammatory)
0.976 0.024 0.000
J86 Pyothorax
0.976 0.024 0.000
N19 Unspecified renal failure
0.976 0.024 0.000
G51.0 Bell's palsy
0.975 0.025 0.000
W07 Fall involving chair
0.975 0.025 0.000
G20-G26 Extrapyramidal and movement disorders
0.975 0.025 0.000
Chapter XXII Codes for special purposes
0.975 0.025 0.000
C45 Mesothelioma
0.974 0.026 0.000
G62.8 Other specified polyneuropathies
0.974 0.026 0.000
F33 Recurrent depressive disorder
0.974 0.026 0.000
I21 Acute myocardial infarction
0.974 0.026 0.000
M79.1 Myalgia
0.974 0.026 0.000
T17 Foreign body in respiratory tract
0.974 0.026 0.000
I50.1 Left ventricular failure
0.973 0.027 0.000
I12.0 Hypertensive renal disease with renal failure
0.973 0.027 0.000
D86.1 Sarcoidosis of lymph nodes
0.973 0.027 0.000
M81.4 Drug-induced osteoporosis
0.973 0.027 0.000
L90 Atrophic disorders of skin
0.972 0.028 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.972 0.028 0.000
S62 Fracture at wrist and hand level
0.972 0.028 0.000
F31 Bipolar affective disorder
0.971 0.029 0.000
R01.1 Cardiac murmur, unspecified
0.971 0.029 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.971 0.029 0.000
M05 Seropositive rheumatoid arthritis
0.970 0.030 0.000
I12.9 Hypertensive renal disease without renal failure
0.970 0.030 0.000
G93.0 Cerebral cysts
0.969 0.031 0.000
I42.0 Dilated cardiomyopathy
0.969 0.031 0.000
T79-T79 Certain early complications of trauma
0.969 0.031 0.000
S02 Fracture of skull and facial bones
0.969 0.031 0.000
D86.9 Sarcoidosis, unspecified
0.968 0.032 0.000
M21.0 Valgus deformity, not elsewhere classified
0.968 0.032 0.000
O20.0 Threatened abortion
0.967 0.033 0.000
S40-S49 Injuries to the shoulder and upper arm
0.967 0.033 0.000
E29 Testicular dysfunction
0.967 0.033 0.000
S05 Injury of eye and orbit
0.967 0.033 0.000
C15-C26 Malignant neoplasms of digestive organs
0.967 0.033 0.000
L90.0 Lichen sclerosus et atrophicus
0.967 0.033 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.967 0.033 0.000
C71.2 Temporal lobe
0.966 0.034 0.000
T90 Sequelae of injuries of head
0.966 0.034 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.966 0.034 0.000
I24 Other acute ischaemic heart diseases
0.966 0.034 0.000
S90-S99 Injuries to the ankle and foot
0.966 0.034 0.000
Q80-Q89 Other congenital malformations
0.965 0.035 0.000
M19.9 Arthrosis, unspecified
0.965 0.035 0.000
E83.1 Disorders of iron metabolism
0.965 0.035 0.000
T86 Failure and rejection of transplanted organs and tissues
0.965 0.035 0.000
S70 Superficial injury of hip and thigh
0.964 0.036 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.964 0.036 0.000
J80 Adult respiratory distress syndrome
0.964 0.036 0.000
V40-V49 Car occupant injured in transport accident
0.964 0.036 0.000
S67 Crushing injury of wrist and hand
0.964 0.036 0.000
O44.1 Placenta praevia with haemorrhage
0.963 0.037 0.000
M06.0 Seronegative rheumatoid arthritis
0.963 0.037 0.000
J86.9 Pyothorax without fistula
0.963 0.037 0.000
G70-G73 Diseases of myoneural junction and muscle
0.962 0.038 0.000
I35.9 Aortic valve disorder, unspecified
0.962 0.038 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.962 0.038 0.000
I05-I09 Chronic rheumatic heart diseases
0.961 0.039 0.000
I21.4 Acute subendocardial myocardial infarction
0.960 0.040 0.000
Z73.3 Stress, not elsewhere classified
0.960 0.040 0.000
M35.0 Sicca syndrome [Sjogren]
0.960 0.040 0.000
I24.8 Other forms of acute ischaemic heart disease
0.959 0.041 0.000
R44.0 Auditory hallucinations
0.959 0.041 0.000
H90-H95 Other disorders of ear
0.959 0.041 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.959 0.041 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.959 0.041 0.000
G25 Other extrapyramidal and movement disorders
0.958 0.042 0.000
E10.2 With renal complications
0.958 0.042 0.000
G40 Epilepsy
0.957 0.043 0.000
B00 Herpesviral [herpes simplex] infections
0.957 0.043 0.000
A00-A09 Intestinal infectious diseases
0.957 0.043 0.000
S00 Superficial injury of head
0.957 0.043 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.957 0.043 0.000
M19.94 Arthrosis, unspecified (Hand)
0.957 0.043 0.000
M65-M68 Disorders of synovium and tendon
0.957 0.043 0.000
I73 Other peripheral vascular diseases
0.957 0.043 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.956 0.044 0.000
M25.3 Other instability of joint
0.956 0.044 0.000
R44.1 Visual hallucinations
0.956 0.044 0.000
N18.2 Chronic kidney disease, stage 2
0.955 0.045 0.000
H65 Nonsuppurative otitis media
0.954 0.046 0.000
Y40 Systemic antibiotics
0.954 0.046 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.953 0.047 0.000
F60 Specific personality disorders
0.952 0.048 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.952 0.048 0.000
H66.3 Other chronic suppurative otitis media
0.952 0.048 0.000
A49.8 Other bacterial infections of unspecified site
0.951 0.049 0.000
G47 Sleep disorders
0.951 0.049 0.000
A49.0 Staphylococcal infection, unspecified
0.951 0.049 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.951 0.049 0.000
O82 Single delivery by Caesarean section
0.950 0.050 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.949 0.051 0.000
S06.8 Other intracranial injuries
0.949 0.051 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.949 0.051 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.948 0.052 0.000
S10-S19 Injuries to the neck
0.948 0.052 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.948 0.052 0.000
G95 Other diseases of spinal cord
0.947 0.053 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.947 0.053 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.947 0.053 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.946 0.054 0.000
Y52.1 Calcium-channel blockers
0.946 0.054 0.000
G30-G32 Other degenerative diseases of the nervous system
0.946 0.054 0.000
G61 Inflammatory polyneuropathy
0.946 0.054 0.000
G83.4 Cauda equina syndrome
0.946 0.054 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.945 0.055 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.945 0.055 0.000
G93.8 Other specified disorders of brain
0.945 0.055 0.000
T66-T78 Other and unspecified effects of external causes
0.945 0.055 0.000
I42.2 Other hypertrophic cardiomyopathy
0.945 0.055 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.945 0.055 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.945 0.055 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.945 0.055 0.000
L73 Other follicular disorders
0.945 0.055 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.945 0.055 0.000
J18 Pneumonia, organism unspecified
0.945 0.055 0.000
G25.0 Essential tremor
0.944 0.056 0.000
Z63.7 Other stressful life events affecting family and household
0.944 0.056 0.000
H21 Other disorders of iris and ciliary body
0.944 0.056 0.000
L60 Nail disorders
0.944 0.056 0.000
B49 Unspecified mycosis
0.944 0.056 0.000
E29.1 Testicular hypofunction
0.944 0.056 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.944 0.056 0.000
S71 Open wound of hip and thigh
0.943 0.057 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.943 0.057 0.000
O36 Maternal care for other known or suspected foetal problems
0.942 0.058 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.942 0.058 0.000
I34 Nonrheumatic mitral valve disorders
0.942 0.058 0.000
H74 Other disorders of middle ear and mastoid
0.942 0.058 0.000
Z71.3 Dietary counselling and surveillance
0.942 0.058 0.000
B37 Candidiasis
0.942 0.058 0.000
A41.8 Other specified septicaemia
0.941 0.059 0.000
D50-D53 Nutritional anaemias
0.941 0.059 0.000
E11.1 With ketoacidosis
0.941 0.059 0.000
C64-C68 Malignant neoplasms of urinary tract
0.941 0.059 0.000
I69 Sequelae of cerebrovascular disease
0.940 0.060 0.000
B44 Aspergillosis
0.939 0.061 0.000
I50.9 Heart failure, unspecified
0.939 0.061 0.000
A46 Erysipelas
0.939 0.061 0.000
I72.0 Aneurysm of carotid artery
0.939 0.061 0.000
D68.0 Von Willebrand's disease
0.938 0.062 0.000
I37 Pulmonary valve disorders
0.938 0.062 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.938 0.062 0.000
Q21 Congenital malformations of cardiac septa
0.938 0.062 0.000
N04 Nephrotic syndrome
0.938 0.062 0.000
N05.9 Unspecified
0.937 0.063 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.937 0.063 0.000
O21 Excessive vomiting in pregnancy
0.937 0.063 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.936 0.064 0.000
C45.9 Mesothelioma, unspecified
0.936 0.064 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.936 0.064 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.936 0.064 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.935 0.065 0.000
A04 Other bacterial intestinal infections
0.934 0.066 0.000
J81 Pulmonary oedema
0.934 0.066 0.000
Z73.8 Other problems related to life-management difficulty
0.934 0.066 0.000
Z63.4 Disappearance and death of family member
0.934 0.066 0.000
Y45.1 Salicylates
0.934 0.066 0.000
L50-L54 Urticaria and erythema
0.933 0.067 0.000
S51 Open wound of forearm
0.933 0.067 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.932 0.068 0.000
H16 Keratitis
0.932 0.068 0.000
C16 Malignant neoplasm of stomach
0.932 0.068 0.000
C17 Malignant neoplasm of small intestine
0.932 0.068 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.931 0.069 0.000
E22 Hyperfunction of pituitary gland
0.931 0.069 0.000
Y45.0 Opioids and related analgesics
0.931 0.069 0.000
D48.6 Breast
0.931 0.069 0.000
D86.8 Sarcoidosis of other and combined sites
0.931 0.069 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.930 0.070 0.000
B18 Chronic viral hepatitis
0.930 0.070 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.930 0.070 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.930 0.070 0.000
T92 Sequelae of injuries of upper limb
0.930 0.070 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.929 0.071 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.928 0.072 0.000
T93 Sequelae of injuries of lower limb
0.928 0.072 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.928 0.072 0.000
I25.3 Aneurysm of heart
0.928 0.072 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.927 0.073 0.000
D68.2 Hereditary deficiency of other clotting factors
0.926 0.074 0.000
T86.1 Kidney transplant failure and rejection
0.926 0.074 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.926 0.074 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.926 0.074 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.926 0.074 0.000
H46 Optic neuritis
0.925 0.075 0.000
I42.9 Cardiomyopathy, unspecified
0.925 0.075 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.925 0.075 0.000
J98 Other respiratory disorders
0.925 0.075 0.000
M71 Other bursopathies
0.924 0.076 0.000
H72 Perforation of tympanic membrane
0.924 0.076 0.000
H10-H13 Disorders of conjunctiva
0.923 0.077 0.000
M70.4 Prepatellar bursitis
0.923 0.077 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.922 0.078 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.922 0.078 0.000
S60 Superficial injury of wrist and hand
0.922 0.078 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.922 0.078 0.000
Y44 Agents primarily affecting blood constituents
0.922 0.078 0.000
J18.9 Pneumonia, unspecified
0.922 0.078 0.000
B37.8 Candidiasis of other sites
0.921 0.079 0.000
M23.8 Other internal derangements of knee
0.921 0.079 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.921 0.079 0.000
G93.9 Disorder of brain, unspecified
0.921 0.079 0.000
I95.8 Other hypotension
0.920 0.080 0.000
M25.9 Joint disorder, unspecified
0.920 0.080 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.920 0.080 0.000
N18.3 Chronic kidney disease, stage 3
0.920 0.080 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.919 0.081 0.000
E13 Other specified diabetes mellitus
0.919 0.081 0.000
W18 Other fall on same level
0.919 0.081 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.919 0.081 0.000
Q66 Congenital deformities of feet
0.918 0.082 0.000
M81.9 Osteoporosis, unspecified
0.917 0.083 0.000
W06 Fall involving bed
0.917 0.083 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.916 0.084 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.916 0.084 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.916 0.084 0.000
H55-H59 Other disorders of eye and adnexa
0.916 0.084 0.000
Q50-Q56 Congenital malformations of genital organs
0.915 0.085 0.000
I95.2 Hypotension due to drugs
0.915 0.085 0.000
F60.9 Personality disorder, unspecified
0.914 0.086 0.000
M79.5 Residual foreign body in soft tissue
0.914 0.086 0.000
W20-W49 Exposure to inanimate mechanical forces
0.913 0.087 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.913 0.087 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.913 0.087 0.000
B00.1 Herpesviral vesicular dermatitis
0.913 0.087 0.000
M24.26 Disorder of ligament (Lower leg)
0.912 0.088 0.000
J30-J39 Other diseases of upper respiratory tract
0.912 0.088 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.912 0.088 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.912 0.088 0.000
O36.6 Maternal care for excessive foetal growth
0.912 0.088 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.911 0.089 0.000
W07.9 Unspecified place
0.911 0.089 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.911 0.089 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.911 0.089 0.000
D68.6 Other Thrombophilia
0.910 0.090 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.910 0.090 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.910 0.090 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.910 0.090 0.000
M79.10 Myalgia (Multiple sites)
0.909 0.091 0.000
I33 Acute and subacute endocarditis
0.909 0.091 0.000
O23 Infections of genito-urinary tract in pregnancy
0.909 0.091 0.000
W50-W64 Exposure to animate mechanical forces
0.909 0.091 0.000
O41 Other disorders of amniotic fluid and membranes
0.908 0.092 0.000
U51 Admission status on psychiatric patients
0.907 0.093 0.000
S41 Open wound of shoulder and upper arm
0.907 0.093 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.907 0.093 0.000
G62.0 Drug-induced polyneuropathy
0.907 0.093 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.907 0.093 0.000
I60 Subarachnoid haemorrhage
0.906 0.094 0.000
I21.9 Acute myocardial infarction, unspecified
0.906 0.094 0.000
I51.4 Myocarditis, unspecified
0.906 0.094 0.000
G82 Paraplegia and tetraplegia
0.906 0.094 0.000
M24.23 Disorder of ligament (Forearm)
0.905 0.095 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.905 0.095 0.000
M95.0 Acquired deformity of nose
0.905 0.095 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.905 0.095 0.000
M65 Synovitis and tenosynovitis
0.905 0.095 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.905 0.095 0.000
Y57 Other and unspecified drugs and medicaments
0.905 0.095 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.905 0.095 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.904 0.096 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.904 0.096 0.000
S71.1 Open wound of thigh
0.904 0.096 0.000
E11.6 With other specified complications
0.903 0.097 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.903 0.097 0.000
D69.5 Secondary thrombocytopenia
0.903 0.097 0.000
O80 Single spontaneous delivery
0.903 0.097 0.000
W07.0 Home
0.902 0.098 0.000
S68 Traumatic amputation of wrist and hand
0.902 0.098 0.000
Z56 Problems related to employment and unemployment
0.902 0.098 0.000
S02.1 Fracture of base of skull
0.902 0.098 0.000
R74 Abnormal serum enzyme levels
0.902 0.098 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.901 0.099 0.000
N18.8 Other chronic renal failure
0.901 0.099 0.000
L20-L30 Dermatitis and eczema
0.900 0.100 0.000
G47.8 Other sleep disorders
0.900 0.100 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.900 0.100 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.900 0.100 0.000
D68.5 Primary Thrombophilia
0.899 0.101 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.899 0.101 0.000
I34.0 Mitral (valve) insufficiency
0.899 0.101 0.000
B07 Viral warts
0.898 0.102 0.000
X60-X84 Intentional self-harm
0.898 0.102 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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