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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116955587
log Bayes Factor = 13.3887
Chromosome 6   position 97,757,667  (GRCh37) Explore rs116955587 on Ensembl!
Variant rs116955587 is part of Cluster X0142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
N18 Chronic renal failure
0.998 0.002 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.997 0.003 0.000
I25.2 Old myocardial infarction
0.994 0.006 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.989 0.011 0.000
I73 Other peripheral vascular diseases
0.988 0.012 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.986 0.014 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.985 0.015 0.000
E78.5 Hyperlipidaemia, unspecified
0.981 0.019 0.000
N19 Unspecified renal failure
0.976 0.024 0.000
I73.9 Peripheral vascular disease, unspecified
0.973 0.027 0.000
N00-N08 Glomerular diseases
0.973 0.027 0.000
I25.1 Atherosclerotic heart disease
0.971 0.029 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.970 0.030 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.970 0.030 0.000
E10-E14 Diabetes mellitus
0.969 0.031 0.000
Chapter II Neoplasms
0.966 0.034 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.959 0.041 0.000
Chapter X Diseases of the respiratory system
0.952 0.048 0.000
N18.5 Chronic kidney disease, stage 5
0.941 0.059 0.000
Chapter VI Diseases of the nervous system
0.940 0.060 0.000
N18.4 Chronic kidney disease, stage 4
0.937 0.063 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.935 0.065 0.000
E83 Disorders of mineral metabolism
0.929 0.071 0.000
I74 Arterial embolism and thrombosis
0.927 0.073 0.000
E11 Non-insulin-dependent diabetes mellitus
0.921 0.079 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.920 0.080 0.000
L60-L75 Disorders of skin appendages
0.918 0.082 0.000
J09-J18 Influenza and pneumonia
0.914 0.086 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.911 0.089 0.000
E87.6 Hypokalaemia
0.909 0.091 0.000
Chapter VII Diseases of the eye and adnexa
0.908 0.092 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.903 0.097 0.000
E86 Volume depletion
0.900 0.100 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.891 0.109 0.000
I21 Acute myocardial infarction
0.889 0.111 0.000
N17 Acute renal failure
0.889 0.111 0.000
C15-C26 Malignant neoplasms of digestive organs
0.888 0.112 0.000
N03 Chronic nephritic syndrome
0.887 0.112 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.886 0.114 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.884 0.116 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.876 0.124 0.000
I73.0 Raynaud's syndrome
0.873 0.127 0.000
N18.3 Chronic kidney disease, stage 3
0.872 0.128 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.870 0.130 0.000
J90-J94 Other diseases of pleura
0.868 0.132 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.865 0.135 0.000
O00-O08 Pregnancy with abortive outcome
0.862 0.138 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.861 0.139 0.000
G40-G47 Episodic and paroxysmal disorders
0.858 0.142 0.000
G90-G99 Other disorders of the nervous system
0.857 0.143 0.000
L89 Decubitus ulcer
0.856 0.144 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.852 0.148 0.000
N18.9 Chronic renal failure, unspecified
0.851 0.149 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.848 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.848 0.152 0.000
E87.7 Fluid overload
0.847 0.153 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.845 0.155 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.844 0.156 0.000
N18.0 End-stage renal disease
0.840 0.160 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.839 0.161 0.000
S60-S69 Injuries to the wrist and hand
0.838 0.162 0.000
N40-N51 Diseases of male genital organs
0.837 0.163 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.837 0.163 0.000
N99-N99 Other disorders of the genitourinary system
0.835 0.165 0.000
N05 Unspecified nephritic syndrome
0.833 0.167 0.000
S80-S89 Injuries to the knee and lower leg
0.832 0.168 0.000
I21.9 Acute myocardial infarction, unspecified
0.830 0.170 0.000
L90 Atrophic disorders of skin
0.830 0.170 0.000
J18 Pneumonia, organism unspecified
0.829 0.171 0.000
C71 Malignant neoplasm of brain
0.829 0.171 0.000
N03.9 Unspecified
0.827 0.173 0.000
E10 Insulin-dependent diabetes mellitus
0.824 0.176 0.000
J90 Pleural effusion, not elsewhere classified
0.821 0.179 0.000
S40-S49 Injuries to the shoulder and upper arm
0.820 0.180 0.000
L72.0 Epidermal cyst
0.819 0.181 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.818 0.182 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.817 0.183 0.000
O02 Other abnormal products of conception
0.816 0.184 0.000
D50-D53 Nutritional anaemias
0.815 0.185 0.000
S20-S29 Injuries to the thorax
0.815 0.185 0.000
E83.3 Disorders of phosphorus metabolism
0.813 0.187 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.812 0.188 0.000
G40 Epilepsy
0.809 0.191 0.000
N17.9 Acute renal failure, unspecified
0.809 0.191 0.000
N04 Nephrotic syndrome
0.808 0.192 0.000
J18.9 Pneumonia, unspecified
0.805 0.195 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.803 0.197 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.801 0.199 0.000
L85 Other epidermal thickening
0.800 0.200 0.000
I30-I52 Other forms of heart disease
0.800 0.200 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.798 0.202 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.794 0.206 0.000
I77 Other disorders of arteries and arterioles
0.793 0.207 0.000
L40-L45 Papulosquamous disorders
0.791 0.209 0.000
C45 Mesothelioma
0.789 0.211 0.000
D69 Purpura and other haemorrhagic conditions
0.785 0.215 0.000
E11.2 With renal complications
0.785 0.215 0.000
J40-J47 Chronic lower respiratory diseases
0.784 0.216 0.000
O02.1 Missed abortion
0.778 0.221 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.777 0.223 0.000
E83.4 Disorders of magnesium metabolism
0.776 0.224 0.000
S00-S09 Injuries to the head
0.776 0.224 0.000
E11.4 With neurological complications
0.776 0.224 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.775 0.225 0.000
I25.5 Ischaemic cardiomyopathy
0.774 0.226 0.000
H53-H54 Visual disturbances and blindness
0.774 0.226 0.000
L20-L30 Dermatitis and eczema
0.773 0.227 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.771 0.229 0.000
G93 Other disorders of brain
0.771 0.229 0.000
C20 Malignant neoplasm of rectum
0.770 0.230 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.767 0.233 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.767 0.233 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.766 0.234 0.000
N18.2 Chronic kidney disease, stage 2
0.766 0.234 0.000
I74.5 Embolism and thrombosis of iliac artery
0.765 0.235 0.000
E83.1 Disorders of iron metabolism
0.765 0.235 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.762 0.238 0.000
E11.6 With other specified complications
0.759 0.241 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.759 0.241 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.759 0.241 0.000
L91 Hypertrophic disorders of skin
0.757 0.243 0.000
O36 Maternal care for other known or suspected foetal problems
0.757 0.243 0.000
E11.3 With ophthalmic complications
0.756 0.244 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.756 0.244 0.000
L93 Lupus erythematosus
0.755 0.245 0.000
S10-S19 Injuries to the neck
0.754 0.245 0.000
I20 Angina pectoris
0.749 0.251 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.749 0.251 0.000
M05-M14 Inflammatory polyarthropathies
0.749 0.251 0.000
J60-J70 Lung diseases due to external agents
0.748 0.252 0.000
C25 Malignant neoplasm of pancreas
0.747 0.253 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.746 0.254 0.000
S90-S99 Injuries to the ankle and foot
0.743 0.257 0.000
E78.8 Other disorders of lipoprotein metabolism
0.743 0.257 0.000
I70 Atherosclerosis
0.741 0.258 0.000
N25-N29 Other disorders of kidney and ureter
0.741 0.259 0.000
E11.5 With peripheral circulatory complications
0.740 0.260 0.000
E87.0 Hyperosmolality and hypernatraemia
0.740 0.260 0.000
C71.2 Temporal lobe
0.739 0.261 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.736 0.263 0.000
H10-H13 Disorders of conjunctiva
0.732 0.268 0.000
C22.1 Intrahepatic bile duct carcinoma
0.732 0.268 0.000
E14 Unspecified diabetes mellitus
0.732 0.268 0.000
E20-E35 Disorders of other endocrine glands
0.731 0.269 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.731 0.269 0.000
G40.9 Epilepsy, unspecified
0.731 0.269 0.000
O20 Haemorrhage in early pregnancy
0.730 0.270 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.729 0.271 0.000
G90 Disorders of autonomic nervous system
0.729 0.271 0.000
T93 Sequelae of injuries of lower limb
0.727 0.273 0.000
I50 Heart failure
0.726 0.274 0.000
D80-D89 Certain disorders involving the immune mechanism
0.725 0.275 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.724 0.276 0.000
Chapter XXII Codes for special purposes
0.723 0.277 0.000
E11.1 With ketoacidosis
0.723 0.277 0.000
D69.6 Thrombocytopenia, unspecified
0.723 0.277 0.000
J00-J06 Acute upper respiratory infections
0.723 0.277 0.000
H55-H59 Other disorders of eye and adnexa
0.720 0.280 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.718 0.282 0.000
C83.3 Large cell (diffuse)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
S81 Open wound of lower leg
0.717 0.283 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.716 0.284 0.000
N50 Other disorders of male genital organs
0.716 0.284 0.000
N18.8 Other chronic renal failure
0.715 0.284 0.000
N18.1 Chronic kidney disease, stage 1
0.715 0.284 0.000
L81 Other disorders of pigmentation
0.715 0.284 0.000
C91 Lymphoid leukaemia
0.715 0.285 0.000
I72 Other aneurysm
0.712 0.288 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.709 0.291 0.000
G93.9 Disorder of brain, unspecified
0.709 0.291 0.000
L10-L14 Bullous disorders
0.709 0.291 0.000
D00-D09 In situ neoplasms
0.709 0.291 0.000
N10-N16 Renal tubulo-interstitial diseases
0.709 0.291 0.000
I73.8 Other specified peripheral vascular diseases
0.709 0.291 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.709 0.291 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.708 0.292 0.000
L50-L54 Urticaria and erythema
0.707 0.292 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
E78.6 Lipoprotein deficiency
0.707 0.293 0.000
E78.4 Other hyperlipidaemia
0.707 0.293 0.000
E78.3 Hyperchylomicronaemia
0.707 0.293 0.000
E78.2 Mixed hyperlipidaemia
0.707 0.293 0.000
E78.1 Pure hyperglyceridaemia
0.707 0.293 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.707 0.293 0.000
I22 Subsequent myocardial infarction
0.706 0.294 0.000
T33-T35 Frostbite
0.706 0.294 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.706 0.294 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.706 0.294 0.000
T00-T07 Injuries involving multiple body regions
0.706 0.294 0.000
L60 Nail disorders
0.706 0.294 0.000
T86 Failure and rejection of transplanted organs and tissues
0.705 0.295 0.000
D45 Polycythaemia vera
0.703 0.296 0.000
C71.9 Brain, unspecified
0.702 0.298 0.000
Chapter I Certain infectious and parasitic diseases
0.701 0.299 0.000
I42 Cardiomyopathy
0.699 0.301 0.000
D50 Iron deficiency anaemia
0.699 0.301 0.000
L90.0 Lichen sclerosus et atrophicus
0.698 0.302 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.697 0.303 0.000
N06 Isolated proteinuria with specified morphological lesion
0.697 0.303 0.000
N01 Rapidly progressive nephritic syndrome
0.697 0.303 0.000
N00 Acute nephritic syndrome
0.697 0.303 0.000
I50.0 Congestive heart failure
0.696 0.304 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.696 0.304 0.000
E87.4 Mixed disorder of acid-base balance
0.696 0.304 0.000
E87.3 Alkalosis
0.696 0.304 0.000
N05.8 Other
0.696 0.304 0.000
O85-O92 Complications predominantly related to the puerperium
0.696 0.304 0.000
E13 Other specified diabetes mellitus
0.695 0.305 0.000
E12 Malnutrition-related diabetes mellitus
0.695 0.305 0.000
H30-H36 Disorders of choroid and retina
0.695 0.305 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.694 0.306 0.000
M20-M25 Other joint disorders
0.694 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.693 0.307 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.693 0.307 0.000
H43-H45 Disorders of vitreous body and globe
0.692 0.307 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.692 0.308 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.692 0.308 0.000
L89.1 Stage II decubitus ulcer
0.692 0.308 0.000
N04.9 Unspecified
0.691 0.309 0.000
M15-M19 Arthrosis
0.691 0.309 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.689 0.310 0.000
I71 Aortic aneurysm and dissection
0.689 0.311 0.000
N30-N39 Other diseases of urinary system
0.689 0.311 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.688 0.312 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.688 0.312 0.000
L94 Other localised connective tissue disorders
0.688 0.312 0.000
L87 Transepidermal elimination disorders
0.688 0.312 0.000
L88 Pyoderma gangrenosum
0.688 0.312 0.000
L86 Keratoderma in diseases classified elsewhere
0.688 0.312 0.000
L83 Acanthosis nigricans
0.688 0.312 0.000
L80 Vitiligo
0.688 0.312 0.000
H53 Visual disturbances
0.688 0.312 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.687 0.313 0.000
O36.6 Maternal care for excessive foetal growth
0.687 0.313 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.687 0.313 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.687 0.313 0.000
S70-S79 Injuries to the hip and thigh
0.685 0.315 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.685 0.315 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.685 0.315 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.685 0.315 0.000
D66 Hereditary factor VIII deficiency
0.685 0.315 0.000
L40 Psoriasis
0.684 0.316 0.000
S61 Open wound of wrist and hand
0.683 0.317 0.000
M80-M85 Disorders of bone density and structure
0.683 0.317 0.000
S68 Traumatic amputation of wrist and hand
0.682 0.317 0.000
I31 Other diseases of pericardium
0.682 0.318 0.000
S06 Intracranial injury
0.682 0.318 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.682 0.318 0.000
J10 Influenza due to identified influenza virus
0.682 0.318 0.000
C45.9 Mesothelioma, unspecified
0.681 0.319 0.000
I26 Pulmonary embolism
0.681 0.319 0.000
N02 Recurrent and persistent haematuria
0.680 0.320 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.680 0.320 0.000
I24 Other acute ischaemic heart diseases
0.678 0.322 0.000
G20-G26 Extrapyramidal and movement disorders
0.678 0.322 0.000
O48 Prolonged pregnancy
0.678 0.322 0.000
D46 Myelodysplastic syndromes
0.677 0.323 0.000
Chapter XX External causes of morbidity and mortality
0.677 0.323 0.000
J45 Asthma
0.676 0.324 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.676 0.324 0.000
T79-T79 Certain early complications of trauma
0.675 0.325 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.674 0.326 0.000
E10.1 With ketoacidosis
0.673 0.327 0.000
L71 Rosacea
0.672 0.328 0.000
G70-G73 Diseases of myoneural junction and muscle
0.671 0.329 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.671 0.329 0.000
T85.2 Mechanical complication of intraocular lens
0.671 0.329 0.000
D55-D59 Haemolytic anaemias
0.671 0.329 0.000
C45.0 Mesothelioma of pleura
0.669 0.330 0.000
T66-T78 Other and unspecified effects of external causes
0.669 0.331 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.668 0.332 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.668 0.332 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.668 0.332 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.667 0.332 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.666 0.334 0.000
E83.8 Other disorders of mineral metabolism
0.666 0.334 0.000
E83.2 Disorders of zinc metabolism
0.666 0.334 0.000
E83.0 Disorders of copper metabolism
0.666 0.334 0.000
L85.9 Epidermal thickening, unspecified
0.665 0.335 0.000
L90.5 Scar conditions and fibrosis of skin
0.665 0.335 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.664 0.336 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.664 0.336 0.000
I74.8 Embolism and thrombosis of other arteries
0.664 0.336 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.664 0.336 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.664 0.336 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.664 0.336 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.664 0.336 0.000
J42 Unspecified chronic bronchitis
0.664 0.336 0.000
O43 Placental disorders
0.664 0.336 0.000
E00-E07 Disorders of thyroid gland
0.663 0.337 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.663 0.337 0.000
J46 Status asthmaticus
0.662 0.338 0.000
N05.9 Unspecified
0.662 0.338 0.000
L89.2 Stage III decubitus ulcer
0.662 0.338 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.661 0.339 0.000
E10.9 Without complications
0.661 0.339 0.000
M86-M90 Other osteopathies
0.661 0.339 0.000
E11.8 With unspecified complications
0.660 0.340 0.000
E11.7 With multiple complications
0.660 0.340 0.000
E11.0 With coma
0.660 0.340 0.000
D50.8 Other iron deficiency anaemias
0.660 0.340 0.000
T87 Complications peculiar to reattachment and amputation
0.659 0.341 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.659 0.341 0.000
C22.9 Liver, unspecified
0.659 0.341 0.000
H40-H42 Glaucoma
0.659 0.341 0.000
L75 Apocrine sweat disorders
0.658 0.342 0.000
L74 Eccrine sweat disorders
0.658 0.342 0.000
L73 Other follicular disorders
0.658 0.342 0.000
L70 Acne
0.658 0.342 0.000
L68 Hypertrichosis
0.658 0.342 0.000
L67 Hair colour and hair shaft abnormalities
0.658 0.342 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.658 0.342 0.000
L65 Other nonscarring hair loss
0.658 0.342 0.000
L64 Androgenic alopecia
0.658 0.342 0.000
L63 Alopecia areata
0.658 0.342 0.000
L62 Nail disorders in diseases classified elsewhere
0.658 0.342 0.000
G44 Other headache syndromes
0.658 0.342 0.000
E10.4 With neurological complications
0.658 0.342 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.656 0.344 0.000
J17 Pneumonia in diseases classified elsewhere
0.655 0.345 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.655 0.345 0.000
J12 Viral pneumonia, not elsewhere classified
0.655 0.345 0.000
J11 Influenza, virus not identified
0.655 0.345 0.000
J14 Pneumonia due to Haemophilus influenzae
0.655 0.345 0.000
J09 Influenza due to certain identified influenza virus
0.655 0.345 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.655 0.345 0.000
T92 Sequelae of injuries of upper limb
0.654 0.345 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.654 0.346 0.000
M91-M94 Chondropathies
0.654 0.346 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.653 0.347 0.000
C95 Leukaemia of unspecified cell type
0.653 0.347 0.000
C94 Other leukaemias of specified cell type
0.653 0.347 0.000
C93 Monocytic leukaemia
0.653 0.347 0.000
C88 Malignant immunoproliferative diseases
0.653 0.347 0.000
C86 Other specified types of T/NK-cell lymphoma
0.653 0.347 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.653 0.347 0.000
O23 Infections of genito-urinary tract in pregnancy
0.652 0.348 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.651 0.349 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.650 0.350 0.000
C92 Myeloid leukaemia
0.649 0.351 0.000
O21 Excessive vomiting in pregnancy
0.649 0.351 0.000
M10 Gout
0.649 0.351 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.648 0.352 0.000
S61.1 Open wound of finger(s) with damage to nail
0.647 0.353 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.647 0.353 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.647 0.353 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.647 0.353 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.647 0.353 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.647 0.353 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.647 0.353 0.000
S20 Superficial injury of thorax
0.647 0.353 0.000
G43 Migraine
0.647 0.353 0.000
E87.5 Hyperkalaemia
0.647 0.353 0.000
O60-O75 Complications of labour and delivery
0.646 0.354 0.000
M17 Gonarthrosis [arthrosis of knee]
0.646 0.354 0.000
A30-A49 Other bacterial diseases
0.645 0.355 0.000
I21.4 Acute subendocardial myocardial infarction
0.645 0.355 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.645 0.355 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.645 0.355 0.000
D51 Vitamin B12 deficiency anaemia
0.645 0.355 0.000
C18 Malignant neoplasm of colon
0.645 0.355 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.643 0.357 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.642 0.358 0.000
I05-I09 Chronic rheumatic heart diseases
0.642 0.358 0.000
J95-J99 Other diseases of the respiratory system
0.641 0.359 0.000
H25-H28 Disorders of lens
0.641 0.359 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.641 0.359 0.000
J40 Bronchitis, not specified as acute or chronic
0.641 0.359 0.000
C81 Hodgkin's disease
0.640 0.360 0.000
I10-I15 Hypertensive diseases
0.640 0.360 0.000
S02 Fracture of skull and facial bones
0.639 0.360 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.639 0.361 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.638 0.362 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.638 0.362 0.000
M25 Other joint disorders, not elsewhere classified
0.638 0.362 0.000
N45 Orchitis and epididymitis
0.637 0.363 0.000
N17.8 Other acute renal failure
0.637 0.363 0.000
N17.2 Acute renal failure with medullary necrosis
0.637 0.363 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.637 0.363 0.000
N17.0 Acute renal failure with tubular necrosis
0.637 0.363 0.000
J93 Pneumothorax
0.637 0.363 0.000
T81 Complications of procedures, not elsewhere classified
0.637 0.363 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.637 0.363 0.000
C25.0 Head of pancreas
0.637 0.363 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.636 0.363 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.636 0.363 0.000
C21 Malignant neoplasm of anus and anal canal
0.636 0.363 0.000
C17 Malignant neoplasm of small intestine
0.636 0.363 0.000
C23 Malignant neoplasm of gallbladder
0.636 0.363 0.000
N03.8 Other
0.636 0.364 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.636 0.364 0.000
N03.6 Dense deposit disease
0.636 0.364 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.636 0.364 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.636 0.364 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.636 0.364 0.000
N03.2 Diffuse membranous glomerulonephritis
0.636 0.364 0.000
N03.1 Focal and segmental glomerular lesions
0.636 0.364 0.000
N03.0 Minor glomerular abnormality
0.636 0.364 0.000
E88 Other metabolic disorders
0.636 0.364 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.636 0.364 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.636 0.364 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.635 0.365 0.000
C70 Malignant neoplasm of meninges
0.635 0.365 0.000
C69 Malignant neoplasm of eye and adnexa
0.635 0.365 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.634 0.365 0.000
L40.9 Psoriasis, unspecified
0.634 0.366 0.000
M17.9 Gonarthrosis, unspecified
0.634 0.366 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.634 0.366 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.634 0.366 0.000
S50-S59 Injuries to the elbow and forearm
0.634 0.366 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.634 0.366 0.000
D73 Diseases of spleen
0.634 0.366 0.000
G93.8 Other specified disorders of brain
0.633 0.367 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.633 0.367 0.000
C71.1 Frontal lobe
0.631 0.369 0.000
G30-G32 Other degenerative diseases of the nervous system
0.631 0.369 0.000
O20.0 Threatened abortion
0.630 0.370 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.630 0.370 0.000
S62 Fracture at wrist and hand level
0.629 0.370 0.000
O45 Premature separation of placenta [abruptio placentae]
0.628 0.372 0.000
O44 Placenta praevia
0.628 0.372 0.000
O41 Other disorders of amniotic fluid and membranes
0.628 0.372 0.000
O33 Maternal care for known or suspected disproportion
0.628 0.372 0.000
O31 Complications specific to multiple gestation
0.628 0.372 0.000
O40 Polyhydramnios
0.628 0.372 0.000
H53.2 Diplopia
0.627 0.373 0.000
S27 Injury of other and unspecified intrathoracic organs
0.627 0.373 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.627 0.373 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.626 0.374 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.625 0.375 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.624 0.376 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.624 0.376 0.000
C46 Kaposi's sarcoma
0.624 0.376 0.000
J45.9 Asthma, unspecified
0.624 0.376 0.000
D69.5 Secondary thrombocytopenia
0.624 0.376 0.000
S64 Injury of nerves at wrist and hand level
0.624 0.376 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.623 0.377 0.000
J94 Other pleural conditions
0.623 0.377 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.622 0.378 0.000
C01 Malignant neoplasm of base of tongue
0.622 0.378 0.000
L29 Pruritus
0.621 0.378 0.000
S40 Superficial injury of shoulder and upper arm
0.621 0.379 0.000
M45-M49 Spondylopathies
0.621 0.379 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.620 0.380 0.000
O29 Complications of anaesthesia during pregnancy
0.620 0.380 0.000
O28 Abnormal findings on antenatal screening of mother
0.620 0.380 0.000
O24 Diabetes mellitus in pregnancy
0.620 0.380 0.000
O22 Venous complications in pregnancy
0.620 0.380 0.000
O25 Malnutrition in pregnancy
0.620 0.380 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.619 0.381 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.618 0.382 0.000
O07 Failed attempted abortion
0.618 0.382 0.000
O06 Unspecified abortion
0.618 0.382 0.000
O05 Other abortion
0.618 0.382 0.000
O01 Hydatidiform mole
0.618 0.382 0.000
O80-O84 Delivery
0.618 0.382 0.000
O30 Multiple gestation
0.617 0.383 0.000
M00-M03 Infectious arthropathies
0.616 0.384 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.616 0.384 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.616 0.384 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.615 0.385 0.000
G41 Status epilepticus
0.615 0.385 0.000
G91 Hydrocephalus
0.615 0.385 0.000
G95 Other diseases of spinal cord
0.614 0.385 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.614 0.385 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.614 0.385 0.000
G92 Toxic encephalopathy
0.614 0.385 0.000
E83.5 Disorders of calcium metabolism
0.614 0.385 0.000
G96 Other disorders of central nervous system
0.614 0.386 0.000
I30 Acute pericarditis
0.614 0.386 0.000
L89.3 Stage IV decubitus ulcer
0.614 0.386 0.000
N50.1 Vascular disorders of male genital organs
0.613 0.387 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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