TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs10774624
log Bayes Factor = 108.174
Chromosome 12   position 111,833,788  (GRCh37) Explore rs10774624 on Ensembl!
Variant rs10774624 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
I25.2 Old myocardial infarction
0.000 0.001 0.999
I20.9 Angina pectoris, unspecified
0.000 0.002 0.998
I20 Angina pectoris
0.000 0.002 0.998
Z95.4 Presence of other heart-valve replacement
0.000 0.003 0.997
Z95.2 Presence of prosthetic heart valve
0.000 0.003 0.997
E27 Other disorders of adrenal gland
0.000 0.006 0.994
E10.9 Without complications
0.000 0.007 0.993
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.008 0.992
E06 Thyroiditis
0.000 0.009 0.991
I74 Arterial embolism and thrombosis
0.000 0.016 0.984
C77.3 Axillary and upper limb lymph nodes
0.984 0.016 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.018 0.982
E10.5 With peripheral circulatory complications
0.000 0.021 0.979
E05.9 Thyrotoxicosis, unspecified
0.000 0.022 0.978
I22 Subsequent myocardial infarction
0.000 0.023 0.977
E27.1 Primary adrenocortical insufficiency
0.000 0.024 0.976
E10.3 With ophthalmic complications
0.000 0.026 0.974
I25.5 Ischaemic cardiomyopathy
0.000 0.026 0.974
E10.1 With ketoacidosis
0.000 0.030 0.970
E06.3 Autoimmune thyroiditis
0.000 0.033 0.967
E10.4 With neurological complications
0.000 0.033 0.967
E23 Hypofunction and other disorders of pituitary gland
0.000 0.045 0.955
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.051 0.949
I21.9 Acute myocardial infarction, unspecified
0.000 0.059 0.941
E50-E64 Other nutritional deficiencies
0.000 0.062 0.938
I73 Other peripheral vascular diseases
0.000 0.069 0.931
E07 Other disorders of thyroid
0.000 0.074 0.926
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.079 0.921
I73.9 Peripheral vascular disease, unspecified
0.000 0.082 0.918
E06.9 Thyroiditis, unspecified
0.000 0.085 0.915
E10.0 With coma
0.000 0.085 0.915
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.094 0.906
E10.2 With renal complications
0.000 0.099 0.901
E23.2 Diabetes insipidus
0.000 0.104 0.896
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.105 0.895
I74.5 Embolism and thrombosis of iliac artery
0.000 0.107 0.893
E07.9 Disorder of thyroid, unspecified
0.000 0.112 0.888
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.115 0.885
E22 Hyperfunction of pituitary gland
0.000 0.135 0.865
E27.2 Addisonian crisis
0.000 0.142 0.858
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.145 0.855
E23.6 Other disorders of pituitary gland
0.000 0.151 0.849
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.160 0.840
I77 Other disorders of arteries and arterioles
0.000 0.161 0.839
E20 Hypoparathyroidism
0.000 0.166 0.834
E28 Ovarian dysfunction
0.000 0.168 0.832
E27.8 Other specified disorders of adrenal gland
0.000 0.174 0.826
I23 Certain current complications following acute myocardial infarction
0.000 0.177 0.823
I25.3 Aneurysm of heart
0.000 0.188 0.812
E58 Dietary calcium deficiency
0.000 0.194 0.806
E34 Other endocrine disorders
0.000 0.198 0.802
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.201 0.799
I77.6 Arteritis, unspecified
0.000 0.202 0.798
E31 Polyglandular dysfunction
0.000 0.204 0.796
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.210 0.790
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.212 0.788
E55 Vitamin D deficiency
0.000 0.220 0.780
E53 Deficiency of other B group vitamins
0.000 0.224 0.776
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.227 0.773
E61 Deficiency of other nutrient elements
0.000 0.228 0.772
I25.6 Silent myocardial ischaemia
0.000 0.232 0.768
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.233 0.767
E22.1 Hyperprolactinaemia
0.000 0.237 0.763
C50 Malignant neoplasm of breast
0.762 0.238 0.000
E40-E46 Malnutrition
0.000 0.239 0.761
E06.1 Subacute thyroiditis
0.000 0.240 0.760
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.760 0.240 0.000
Z95.3 Presence of xenogenic heart valve
0.000 0.251 0.749
I12 Hypertensive renal disease
0.000 0.253 0.747
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.253 0.746
C50.9 Breast, unspecified
0.746 0.254 0.000
I72 Other aneurysm
0.000 0.255 0.745
E21.3 Hyperparathyroidism, unspecified
0.000 0.256 0.744
C50.4 Upper-outer quadrant of breast
0.742 0.258 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.260 0.740
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.738 0.262 0.000
E25 Adrenogenital disorders
0.000 0.266 0.734
C50.8 Overlapping lesion of breast
0.733 0.267 0.000
E10.8 With unspecified complications
0.000 0.278 0.722
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.278 0.722
D75 Other diseases of blood and blood-forming organs
0.000 0.279 0.721
E23.0 Hypopituitarism
0.000 0.281 0.719
I15 Secondary hypertension
0.000 0.281 0.719
E28.3 Primary ovarian failure
0.000 0.281 0.719
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.717
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I26 Pulmonary embolism
0.000 0.284 0.716
E20.9 Hypoparathyroidism, unspecified
0.000 0.285 0.715
D75.1 Secondary polycythaemia
0.000 0.285 0.715
E27.5 Adrenomedullary hyperfunction
0.000 0.288 0.712
E27.0 Other adrenocortical overactivity
0.000 0.288 0.712
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.289 0.711
D55-D59 Haemolytic anaemias
0.000 0.289 0.711
E06.4 Drug-induced thyroiditis
0.000 0.289 0.711
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.289 0.711
E06.0 Acute thyroiditis
0.000 0.289 0.711
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.289 0.711
I72.4 Aneurysm of artery of lower extremity
0.000 0.290 0.710
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.292 0.708
I25.4 Coronary artery aneurysm
0.000 0.295 0.704
E05.5 Thyroid crisis or storm
0.000 0.296 0.704
E05.4 Thyrotoxicosis factitia
0.000 0.296 0.704
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.296 0.704
E51 Thiamine deficiency
0.000 0.297 0.703
I21.4 Acute subendocardial myocardial infarction
0.000 0.299 0.701
C50.1 Central portion of breast
0.700 0.300 0.000
I23.8 Other current complications following acute myocardial infarction
0.000 0.304 0.696
C50-C50 Malignant neoplasm of breast
0.695 0.305 0.000
I13 Hypertensive heart and renal disease
0.000 0.306 0.693
E32 Diseases of thymus
0.000 0.307 0.693
D59 Acquired haemolytic anaemia
0.000 0.307 0.693
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.311 0.689
D75.2 Essential thrombocytosis
0.000 0.312 0.688
E03.8 Other specified hypothyroidism
0.000 0.313 0.687
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.315 0.685
E23.1 Drug-induced hypopituitarism
0.000 0.315 0.685
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.320 0.680
I22.8 Subsequent myocardial infarction of other sites
0.000 0.323 0.677
D59.1 Other autoimmune haemolytic anaemias
0.000 0.323 0.677
E06.5 Other chronic thyroiditis
0.000 0.323 0.677
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.325 0.675
E53.9 Vitamin B deficiency, unspecified
0.000 0.325 0.675
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.327 0.673
E63 Other nutritional deficiencies
0.000 0.327 0.673
E50 Vitamin A deficiency
0.000 0.327 0.673
E60 Dietary zinc deficiency
0.000 0.327 0.673
E59 Dietary selenium deficiency
0.000 0.327 0.673
E52 Niacin deficiency [pellagra]
0.000 0.327 0.673
C77.9 Lymph node, unspecified
0.673 0.327 0.000
I77.1 Stricture of artery
0.000 0.328 0.672
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.330 0.670
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.332 0.668
E61.1 Iron deficiency
0.000 0.333 0.667
E55.9 Vitamin D deficiency, unspecified
0.000 0.334 0.666
E07.1 Dyshormogenetic goitre
0.000 0.336 0.664
E07.0 Hypersecretion of calcitonin
0.000 0.336 0.664
D58 Other hereditary haemolytic anaemias
0.000 0.337 0.663
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.338 0.661
C79 Secondary malignant neoplasm of other sites
0.661 0.339 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.345 0.655
I00-I02 Acute rheumatic fever
0.000 0.347 0.653
E31.0 Autoimmune polyglandular failure
0.000 0.349 0.651
Chapter II Neoplasms
0.647 0.353 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.355 0.644
I70 Atherosclerosis
0.000 0.357 0.643
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.643 0.357 0.000
E10.6 With other specified complications
0.000 0.359 0.641
E34.0 Carcinoid syndrome
0.000 0.360 0.640
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.362 0.638
C50.2 Upper-inner quadrant of breast
0.636 0.364 0.000
C77.8 Lymph nodes of multiple regions
0.635 0.365 0.000
E34.9 Endocrine disorder, unspecified
0.000 0.367 0.633
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.369 0.631
E05.8 Other thyrotoxicosis
0.000 0.370 0.630
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.627 0.373 0.000
E26 Hyperaldosteronism
0.000 0.374 0.626
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.375 0.624
C78.7 Secondary malignant neoplasm of liver
0.623 0.377 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.622 0.378 0.000
D56 Thalassaemia
0.000 0.379 0.621
E10.7 With multiple complications
0.000 0.379 0.621
E22.8 Other hyperfunction of pituitary gland
0.000 0.380 0.620
C84 Peripheral and cutaneous T-cell lymphomas
0.618 0.382 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.384 0.615
E56 Other vitamin deficiencies
0.000 0.386 0.614
D80-D89 Certain disorders involving the immune mechanism
0.000 0.388 0.611
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.390 0.610
C50.0 Nipple and areola
0.609 0.391 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.393 0.607
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.397 0.603
I77.0 Arteriovenous fistula, acquired
0.000 0.398 0.602
I77.5 Necrosis of artery
0.000 0.398 0.601
I77.4 Coeliac artery compression syndrome
0.000 0.398 0.601
C79.8 Secondary malignant neoplasm of other specified sites
0.601 0.399 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.599 0.401 0.000
E20.8 Other hypoparathyroidism
0.000 0.402 0.598
E20.1 Pseudohypoparathyroidism
0.000 0.402 0.598
E20.0 Idiopathic hypoparathyroidism
0.000 0.402 0.598
I05-I09 Chronic rheumatic heart diseases
0.000 0.403 0.597
E21.2 Other hyperparathyroidism
0.000 0.403 0.597
E28.9 Ovarian dysfunction, unspecified
0.000 0.404 0.596
E28.8 Other ovarian dysfunction
0.000 0.404 0.596
E28.1 Androgen excess
0.000 0.404 0.596
E28.0 Oestrogen excess
0.000 0.404 0.596
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.407 0.593
E27.9 Disorder of adrenal gland, unspecified
0.000 0.408 0.592
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.410 0.590
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.410 0.590
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.410 0.590
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.410 0.590
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.410 0.590
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.410 0.590
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.410 0.590
E46 Unspecified protein-energy malnutrition
0.000 0.410 0.590
I77.2 Rupture of artery
0.000 0.411 0.588
E14 Unspecified diabetes mellitus
0.000 0.412 0.588
C50.5 Lower-outer quadrant of breast
0.587 0.413 0.000
D86 Sarcoidosis
0.000 0.415 0.585
E54 Ascorbic acid deficiency
0.000 0.416 0.583
E28.2 Polycystic ovarian syndrome
0.000 0.419 0.581
C79.7 Secondary malignant neoplasm of adrenal gland
0.576 0.424 0.000
I77.8 Other specified disorders of arteries and arterioles
0.000 0.425 0.575
E34.5 Androgen resistance syndrome
0.000 0.425 0.575
E34.4 Constitutional tall stature
0.000 0.425 0.575
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.425 0.575
E34.1 Other hypersecretion of intestinal hormones
0.000 0.425 0.575
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.427 0.573
E34.3 Short stature, not elsewhere classified
0.000 0.429 0.571
E31.9 Polyglandular dysfunction, unspecified
0.000 0.429 0.571
E31.8 Other polyglandular dysfunction
0.000 0.429 0.571
E31.1 Polyglandular hyperfunction
0.000 0.429 0.571
C84.0 Mycosis fungoides
0.569 0.431 0.000
I28 Other diseases of pulmonary vessels
0.000 0.432 0.568
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.567 0.433 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.566 0.434 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.434 0.566
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.436 0.564
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.437 0.563
E07.8 Other specified disorders of thyroid
0.000 0.438 0.561
I72.2 Aneurysm of renal artery
0.000 0.439 0.561
C78.2 Secondary malignant neoplasm of pleura
0.561 0.439 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.440 0.560
E55.0 Rickets, active
0.000 0.441 0.559
C77.4 Inguinal and lower limb lymph nodes
0.558 0.442 0.000
D73 Diseases of spleen
0.000 0.444 0.556
E53.1 Pyridoxine deficiency
0.000 0.444 0.556
E53.0 Riboflavin deficiency
0.000 0.444 0.556
D69 Purpura and other haemorrhagic conditions
0.000 0.445 0.555
# Top node
0.000 0.445 0.555
Z95.0 Presence of cardiac pacemaker
0.000 0.446 0.554
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.554 0.446 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.447 0.553
E61.8 Deficiency of other specified nutrient elements
0.000 0.447 0.553
E61.7 Deficiency of multiple nutrient elements
0.000 0.447 0.553
E61.6 Vanadium deficiency
0.000 0.447 0.553
E61.5 Molybdenum deficiency
0.000 0.447 0.553
E61.4 Chromium deficiency
0.000 0.447 0.553
E61.3 Manganese deficiency
0.000 0.447 0.553
E61.0 Copper deficiency
0.000 0.447 0.553
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.552 0.448 0.000
E13 Other specified diabetes mellitus
0.000 0.450 0.550
C85.7 Other specified types of non-Hodgkin's lymphoma
0.548 0.452 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.452 0.548
D86.9 Sarcoidosis, unspecified
0.000 0.452 0.548
I15.0 Renovascular hypertension
0.000 0.452 0.548
I77.3 Arterial fibromuscular dysplasia
0.000 0.453 0.547
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.454 0.546
E45 Retarded development following protein-energy malnutrition
0.000 0.454 0.546
E43 Unspecified severe protein-energy malnutrition
0.000 0.454 0.546
E42 Marasmic kwashiorkor
0.000 0.454 0.546
E41 Nutritional marasmus
0.000 0.454 0.546
E40 Kwashiorkor
0.000 0.454 0.546
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.455 0.545
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.456 0.544
D56.3 Thalassaemia trait
0.000 0.457 0.543
I12.0 Hypertensive renal disease with renal failure
0.000 0.457 0.543
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.458 0.542
E21.0 Primary hyperparathyroidism
0.000 0.461 0.539
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.462 0.538
E34.8 Other specified endocrine disorders
0.000 0.463 0.536
E51.2 Wernicke's encephalopathy
0.000 0.465 0.535
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.466 0.534
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.466 0.534
I74.8 Embolism and thrombosis of other arteries
0.000 0.467 0.533
D58.0 Hereditary spherocytosis
0.000 0.467 0.533
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.467 0.533
D86.0 Sarcoidosis of lung
0.000 0.467 0.533
I15.2 Hypertension secondary to endocrine disorders
0.000 0.468 0.532
C90 Multiple myeloma and malignant plasma cell neoplasms
0.530 0.470 0.000
K90 Intestinal malabsorption
0.000 0.471 0.529
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.473 0.527
D75.0 Familial erythrocytosis
0.000 0.473 0.527
E25.9 Adrenogenital disorder, unspecified
0.000 0.473 0.527
E25.8 Other adrenogenital disorders
0.000 0.473 0.527
D60-D64 Aplastic and other anaemias
0.000 0.474 0.526
E23.7 Disorder of pituitary gland, unspecified
0.000 0.476 0.524
E29 Testicular dysfunction
0.000 0.476 0.524
E61.2 Magnesium deficiency
0.000 0.478 0.522
C84.4 Peripheral T-cell lymphoma
0.522 0.478 0.000
I15.1 Hypertension secondary to other renal disorders
0.000 0.478 0.521
I72.8 Aneurysm of other specified arteries
0.000 0.479 0.521
E53.8 Deficiency of other specified B group vitamins
0.000 0.479 0.521
C76.0 Head, face and neck
0.518 0.482 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.514 0.486 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.488 0.512
D55 Anaemia due to enzyme disorders
0.000 0.490 0.510
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.491 0.509
D74 Methaemoglobinaemia
0.000 0.492 0.507
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.492 0.507
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.492 0.507
D57 Sickle-cell disorders
0.000 0.493 0.507
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.506 0.494 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.496 0.504
E51.9 Thiamine deficiency, unspecified
0.000 0.496 0.504
E51.8 Other manifestations of thiamine deficiency
0.000 0.496 0.504
E51.1 Beriberi
0.000 0.496 0.504
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.496 0.504
D69.4 Other primary thrombocytopenia
0.000 0.498 0.502
Chapter VI Diseases of the nervous system
0.000 0.498 0.502
C84.5 Other and unspecified T-cell lymphomas
0.500 0.500 0.000
I07 Rheumatic tricuspid valve diseases
0.000 0.500 0.500
I70.8 Atherosclerosis of other arteries
0.000 0.502 0.498
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.503 0.497
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.503 0.497
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.503 0.497
E32.9 Disease of thymus, unspecified
0.000 0.503 0.497
E32.1 Abscess of thymus
0.000 0.503 0.497
E32.0 Persistent hyperplasia of thymus
0.000 0.503 0.497
D59.8 Other acquired haemolytic anaemias
0.000 0.503 0.497
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.503 0.497
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.503 0.497
D59.3 Haemolytic-uraemic syndrome
0.000 0.503 0.497
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.503 0.497
I20.1 Angina pectoris with documented spasm
0.000 0.504 0.496
C94 Other leukaemias of specified cell type
0.495 0.505 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.506 0.494
I99 Other and unspecified disorders of circulatory system
0.000 0.507 0.493
G81 Hemiplegia
0.000 0.507 0.493
C76.1 Thorax
0.491 0.509 0.000
G70-G73 Diseases of myoneural junction and muscle
0.000 0.510 0.490
I15.8 Other secondary hypertension
0.000 0.510 0.490
D58.2 Other haemoglobinopathies
0.000 0.510 0.490
G81.9 Hemiplegia, unspecified
0.000 0.511 0.489
D73.3 Abscess of spleen
0.000 0.511 0.489
C86 Other specified types of T/NK-cell lymphoma
0.488 0.512 0.000
I79.1 Aortitis in diseases classified elsewhere
0.000 0.512 0.488
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.512 0.488
E50.9 Vitamin A deficiency, unspecified
0.000 0.517 0.482
E50.8 Other manifestations of vitamin A deficiency
0.000 0.517 0.482
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.517 0.482
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.517 0.482
E50.5 Vitamin A deficiency with night blindness
0.000 0.517 0.482
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.517 0.482
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.517 0.482
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.517 0.482
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.517 0.482
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.517 0.482
E63.9 Nutritional deficiency, unspecified
0.000 0.517 0.482
E63.8 Other specified nutritional deficiencies
0.000 0.517 0.482
E63.1 Imbalance of constituents of food intake
0.000 0.517 0.482
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.517 0.482
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.517 0.482
E64.8 Sequelae of other nutritional deficiencies
0.000 0.517 0.482
E64.3 Sequelae of rickets
0.000 0.517 0.482
E64.2 Sequelae of vitamin C deficiency
0.000 0.517 0.482
E64.1 Sequelae of vitamin A deficiency
0.000 0.517 0.482
E64.0 Sequelae of protein-energy malnutrition
0.000 0.517 0.482
I15.9 Seconday hypertension, unspecified
0.000 0.519 0.481
D72 Other disorders of white blood cells
0.000 0.521 0.479
G20-G26 Extrapyramidal and movement disorders
0.000 0.523 0.477
D56.1 Beta thalassaemia
0.000 0.523 0.477
I70.1 Atherosclerosis of renal artery
0.000 0.524 0.476
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.476 0.524 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.524 0.476
D58.1 Hereditary elliptocytosis
0.000 0.524 0.476
G83 Other paralytic syndromes
0.000 0.524 0.476
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.526 0.474
E32.8 Other diseases of thymus
0.000 0.526 0.474
G24 Dystonia
0.000 0.528 0.472
E14.3 With ophthalmic complications
0.000 0.529 0.471
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.469 0.531 0.000
I02 Rheumatic chorea
0.000 0.532 0.468
I01 Rheumatic fever with heart involvement
0.000 0.532 0.468
C95 Leukaemia of unspecified cell type
0.466 0.534 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.465 0.535 0.000
I11 Hypertensive heart disease
0.000 0.535 0.465
G24.9 Dystonia, unspecified
0.000 0.537 0.463
G71 Primary disorders of muscles
0.000 0.537 0.462
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.461 0.539 0.000
G80 Infantile cerebral palsy
0.000 0.540 0.460
C90.1 Plasma cell leukaemia
0.459 0.541 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.458 0.542 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.543 0.457
G83.4 Cauda equina syndrome
0.000 0.545 0.455
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.547 0.453
D86.1 Sarcoidosis of lymph nodes
0.000 0.547 0.453
C76.3 Pelvis
0.452 0.548 0.000
C82.0 Small cleaved cell, follicular
0.451 0.549 0.000
G72 Other myopathies
0.000 0.551 0.449
E26.8 Other hyperaldosteronism
0.000 0.551 0.449
E26.1 Secondary hyperaldosteronism
0.000 0.551 0.449
C15-C26 Malignant neoplasms of digestive organs
0.449 0.551 0.000
D82 Immunodeficiency associated with other major defects
0.000 0.552 0.448
D83 Common variable immunodeficiency
0.000 0.552 0.448
C81 Hodgkin's disease
0.447 0.553 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.554 0.446
C76.8 Overlapping lesion of other and ill-defined sites
0.446 0.554 0.000
C76.7 Other ill-defined sites
0.446 0.554 0.000
C76.5 Lower limb
0.446 0.554 0.000
C76.4 Upper limb
0.446 0.554 0.000
E14.4 With neurological complications
0.000 0.554 0.446
D56.9 Thalassaemia, unspecified
0.000 0.554 0.446
D56.8 Other thalassaemias
0.000 0.554 0.446
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.554 0.446
D56.2 Delta-beta thalassaemia
0.000 0.554 0.446
D56.0 Alpha thalassaemia
0.000 0.554 0.446
E14.1 With ketoacidosis
0.000 0.555 0.445
I70.9 Generalised and unspecified atherosclerosis
0.000 0.555 0.445
I72.0 Aneurysm of carotid artery
0.000 0.555 0.445
C84.8 Cutaneous T-cell lymphoma, unspecified
0.444 0.556 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.443 0.557 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.443 0.557 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.443 0.557 0.000
C84.3 Lymphoepithelioid lymphoma
0.443 0.557 0.000
C84.2 T-zone lymphoma
0.443 0.557 0.000
C84.1 Sezary's diease
0.443 0.557 0.000
C93 Monocytic leukaemia
0.443 0.557 0.000
I05 Rheumatic mitral valve diseases
0.000 0.558 0.442
E56.9 Vitamin deficiency, unspecified
0.000 0.559 0.440
E56.8 Deficiency of other vitamins
0.000 0.559 0.440
E56.0 Deficiency of vitamin E
0.000 0.559 0.440
D73.4 Cyst of spleen
0.000 0.560 0.440
D81 Combined immunodeficiencies
0.000 0.561 0.438
I72.1 Aneurysm of artery of upper extremity
0.000 0.563 0.437
C83 Diffuse non-Hodgkin's lymphoma
0.434 0.566 0.000
C79.2 Secondary malignant neoplasm of skin
0.434 0.566 0.000
C20 Malignant neoplasm of rectum
0.434 0.566 0.000
I72.9 Aneurysm of unspecified site
0.000 0.567 0.433
E14.5 With peripheral circulatory complications
0.000 0.568 0.432
E14.6 With other specified complications
0.000 0.569 0.431
I07.1 Tricuspid insufficiency
0.000 0.570 0.430
C85.0 Lymphosarcoma
0.430 0.570 0.000
D73.9 Disease of spleen, unspecified
0.000 0.573 0.427
I28.8 Other specified diseases of pulmonary vessels
0.000 0.573 0.427
G71.1 Myotonic disorders
0.000 0.573 0.427
E26.9 Hyperaldosteronism, unspecified
0.000 0.576 0.424
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.576 0.424
C76.2 Abdomen
0.424 0.576 0.000
D73.1 Hypersplenism
0.000 0.577 0.423
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.577 0.423
E14.7 With multiple complications
0.000 0.578 0.422
E14.0 With coma
0.000 0.578 0.422
I78 Diseases of capillaries
0.000 0.579 0.421
G72.9 Myopathy, unspecified
0.000 0.579 0.421
G80.9 Infantile cerebral palsy, unspecified
0.000 0.580 0.420
C51-C58 Malignant neoplasms of female genital organs
0.419 0.581 0.000
C92 Myeloid leukaemia
0.418 0.582 0.000
C90.2 Plasmacytoma, extramedullary
0.417 0.583 0.000
E14.2 Withrenal complications
0.000 0.585 0.415
E24 Cushing's syndrome
0.000 0.585 0.414
I60-I69 Cerebrovascular diseases
0.000 0.586 0.414
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.586 0.414
D86.3 Sarcoidosis of skin
0.000 0.586 0.413
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.587 0.413
C88 Malignant immunoproliferative diseases
0.412 0.588 0.000
I63 Cerebral infarction
0.000 0.589 0.411

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.