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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7167085
log Bayes Factor = 15.101
Chromosome 15   position 91,406,188  (GRCh37) Explore rs7167085 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.001 0.999
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.004 0.996
I10-I15 Hypertensive diseases
0.000 0.010 0.990
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.017 0.983
Chapter IX Diseases of the circulatory system
0.000 0.017 0.983
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.028 0.972
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.028 0.972
Z95.4 Presence of other heart-valve replacement
0.000 0.040 0.960
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.055 0.945
Z95.2 Presence of prosthetic heart valve
0.000 0.058 0.942
I25.2 Old myocardial infarction
0.000 0.070 0.930
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.079 0.921
I99 Other and unspecified disorders of circulatory system
0.000 0.086 0.914
I24 Other acute ischaemic heart diseases
0.000 0.091 0.909
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.098 0.902
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.107 0.893
I24.8 Other forms of acute ischaemic heart disease
0.000 0.117 0.883
I15 Secondary hypertension
0.000 0.124 0.876
I25.3 Aneurysm of heart
0.000 0.134 0.866
I25.4 Coronary artery aneurysm
0.000 0.138 0.862
I21.4 Acute subendocardial myocardial infarction
0.000 0.143 0.857
Z95.3 Presence of xenogenic heart valve
0.000 0.148 0.852
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.153 0.847
I97.1 Other functional disturbances following cardiac surgery
0.000 0.186 0.814
I15.1 Hypertension secondary to other renal disorders
0.000 0.189 0.811
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.192 0.808
I24.1 Dressler's syndrome
0.000 0.232 0.768
I25.5 Ischaemic cardiomyopathy
0.000 0.234 0.766
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.284 0.716
I00-I02 Acute rheumatic fever
0.000 0.292 0.708
I11 Hypertensive heart disease
0.000 0.293 0.707
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.310 0.690
I15.9 Seconday hypertension, unspecified
0.000 0.311 0.689
I13 Hypertensive heart and renal disease
0.000 0.313 0.687
I25.6 Silent myocardial ischaemia
0.000 0.317 0.683
I20 Angina pectoris
0.000 0.338 0.662
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.339 0.661
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.353 0.647
I97.0 Postcardiotomy syndrome
0.000 0.353 0.647
I23 Certain current complications following acute myocardial infarction
0.000 0.357 0.643
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.376 0.624
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.379 0.621
I15.0 Renovascular hypertension
0.000 0.382 0.618
I20.0 Unstable angina
0.000 0.386 0.614
I21.9 Acute myocardial infarction, unspecified
0.000 0.398 0.602
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.406 0.594
Z95.1 Presence of aortocoronary bypass graft
0.000 0.407 0.593
I77 Other disorders of arteries and arterioles
0.000 0.414 0.586
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.417 0.583
I15.8 Other secondary hypertension
0.000 0.423 0.576
I74 Arterial embolism and thrombosis
0.000 0.440 0.560
I15.2 Hypertension secondary to endocrine disorders
0.000 0.449 0.551
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.454 0.546
I22 Subsequent myocardial infarction
0.000 0.463 0.537
I77.1 Stricture of artery
0.000 0.475 0.525
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.481 0.519
I00 Rheumatic fever without mention of heart involvement
0.000 0.489 0.511
I02 Rheumatic chorea
0.000 0.492 0.508
I01 Rheumatic fever with heart involvement
0.000 0.492 0.508
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.494 0.506
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.504 0.496
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.507 0.492
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.507 0.492
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.507 0.492
I20.9 Angina pectoris, unspecified
0.000 0.517 0.483
I77.2 Rupture of artery
0.000 0.521 0.479
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.530 0.469
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.539 0.461
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.539 0.461
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.539 0.461
I05-I09 Chronic rheumatic heart diseases
0.000 0.539 0.461
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.546 0.454
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.548 0.452
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.550 0.450
I77.6 Arteritis, unspecified
0.000 0.552 0.448
I74.5 Embolism and thrombosis of iliac artery
0.000 0.553 0.447
I72 Other aneurysm
0.000 0.557 0.443
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.571 0.429
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.574 0.426
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.577 0.423
I77.5 Necrosis of artery
0.000 0.580 0.420
I77.4 Coeliac artery compression syndrome
0.000 0.580 0.420
I77.3 Arterial fibromuscular dysplasia
0.000 0.580 0.420
I25.0 Atherosclerotic cardiovascular disease, so described
0.001 0.596 0.403
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.609 0.391
I23.8 Other current complications following acute myocardial infarction
0.000 0.612 0.387
I22.8 Subsequent myocardial infarction of other sites
0.000 0.624 0.376
I09 Other rheumatic heart diseases
0.000 0.628 0.372
I72.9 Aneurysm of unspecified site
0.000 0.630 0.370
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.635 0.365
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.636 0.364
I01.8 Other acute rheumatic heart disease
0.000 0.636 0.364
I01.2 Acute rheumatic myocarditis
0.000 0.636 0.364
I01.1 Acute rheumatic endocarditis
0.000 0.636 0.364
I01.0 Acute rheumatic pericarditis
0.000 0.636 0.364
I02.9 Rheumatic chorea without heart involvement
0.000 0.636 0.364
I02.0 Rheumatic chorea with heart involvement
0.000 0.636 0.364
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.637 0.363
I79.1 Aortitis in diseases classified elsewhere
0.000 0.637 0.363
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.637 0.363
I20.1 Angina pectoris with documented spasm
0.000 0.644 0.355
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.652 0.348
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.653 0.347
I72.2 Aneurysm of renal artery
0.000 0.654 0.346
I74.8 Embolism and thrombosis of other arteries
0.000 0.671 0.329
I08 Multiple valve diseases
0.000 0.671 0.329
I26 Pulmonary embolism
0.000 0.672 0.328
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.673 0.327
I72.4 Aneurysm of artery of lower extremity
0.000 0.673 0.327
I72.8 Aneurysm of other specified arteries
0.000 0.679 0.321
I72.1 Aneurysm of artery of upper extremity
0.000 0.680 0.320
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.682 0.318
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.682 0.318
I70 Atherosclerosis
0.000 0.683 0.317
I95 Hypotension
0.000 0.689 0.311
I12 Hypertensive renal disease
0.000 0.689 0.311
I77.0 Arteriovenous fistula, acquired
0.000 0.691 0.309
I09.9 Rheumatic heart disease, unspecified
0.000 0.692 0.308
I06 Rheumatic aortic valve diseases
0.000 0.693 0.307
I72.0 Aneurysm of carotid artery
0.000 0.697 0.303
I27 Other pulmonary heart diseases
0.000 0.698 0.302
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.699 0.301
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.707 0.293
I28 Other diseases of pulmonary vessels
0.000 0.713 0.286
I08.0 Disorders of both mitral and aortic valves
0.000 0.719 0.281
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.724 0.276
I95.0 Idiopathic hypotension
0.000 0.725 0.275
I78 Diseases of capillaries
0.000 0.729 0.271
I09.8 Other specified rheumatic heart diseases
0.000 0.733 0.267
I09.2 Chronic rheumatic pericarditis
0.000 0.733 0.267
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.733 0.267
I09.0 Rheumatic myocarditis
0.000 0.733 0.267
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.750 0.250
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.750 0.249
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.750 0.249
I98.0 Cardiovascular syphilis
0.000 0.750 0.249
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.752 0.248
I70.1 Atherosclerosis of renal artery
0.000 0.754 0.246
I77.8 Other specified disorders of arteries and arterioles
0.000 0.756 0.244
I95.2 Hypotension due to drugs
0.000 0.757 0.243
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.757 0.243
I08.9 Multiple valve disease, unspecified
0.000 0.759 0.241
I27.2 Other secondary pulmonary hypertension
0.000 0.761 0.239
I70.9 Generalised and unspecified atherosclerosis
0.000 0.765 0.235
I27.8 Other specified pulmonary heart diseases
0.000 0.775 0.225
I78.8 Other diseases of capillaries
0.000 0.779 0.221
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.780 0.220
I06.8 Other rheumatic aortic valve diseases
0.000 0.780 0.220
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.780 0.220
I07 Rheumatic tricuspid valve diseases
0.000 0.783 0.217
I05 Rheumatic mitral valve diseases
0.000 0.783 0.217
I27.1 Kyphoscoliotic heart disease
0.000 0.783 0.216
I06.0 Rheumatic aortic stenosis
0.000 0.786 0.214
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.794 0.205
I28.1 Aneurysm of pulmonary artery
0.000 0.794 0.205
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.794 0.205
I06.1 Rheumatic aortic insufficiency
0.000 0.796 0.203
I73 Other peripheral vascular diseases
0.000 0.799 0.201
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.804 0.196
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.808 0.191
I27.9 Pulmonary heart disease, unspecified
0.000 0.810 0.190
I70.8 Atherosclerosis of other arteries
0.001 0.810 0.189
I08.8 Other multiple valve diseases
0.000 0.814 0.186
I78.9 Disease of capillaries, unspecified
0.000 0.821 0.179
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.823 0.177
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.824 0.176
I05.0 Mitral stenosis
0.000 0.825 0.175
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.001 0.830 0.170
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.830 0.169
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.831 0.168
I70.0 Atherosclerosis of aorta
0.001 0.836 0.163
I73.0 Raynaud's syndrome
0.000 0.841 0.159
I72.3 Aneurysm of iliac artery
0.001 0.843 0.157
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.843 0.157
I95.8 Other hypotension
0.000 0.844 0.156
I07.9 Tricuspid valve disease, unspecified
0.000 0.844 0.156
I07.8 Other tricuspid valve diseases
0.000 0.844 0.156
I07.2 Tricuspid stenosis with insufficiency
0.000 0.844 0.156
I07.0 Tricuspid stenosis
0.000 0.844 0.156
I05.8 Other mitral valve diseases
0.000 0.844 0.156
I12.0 Hypertensive renal disease with renal failure
0.000 0.858 0.142
I27.0 Primary pulmonary hypertension
0.000 0.859 0.141
I70.81 Atherosclerosis of other arteries (with gangrene)
0.001 0.864 0.136
I28.8 Other specified diseases of pulmonary vessels
0.001 0.864 0.136
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.870 0.130
I05.9 Mitral valve disease, unspecified
0.000 0.879 0.121
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.880 0.120
Z95.0 Presence of cardiac pacemaker
0.000 0.882 0.118
I70.01 Atherosclerosis of aorta (with gangrene)
0.001 0.882 0.117
I05.2 Mitral stenosis with insufficiency
0.000 0.883 0.117
I05.1 Rheumatic mitral insufficiency
0.000 0.883 0.116
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.887 0.112
I73.8 Other specified peripheral vascular diseases
0.000 0.888 0.111
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.888 0.111
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.101 0.899 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.901 0.098
I95.1 Orthostatic hypotension
0.000 0.920 0.080
E53.8 Deficiency of other specified B group vitamins
0.061 0.939 0.000
I20.8 Other forms of angina pectoris
0.000 0.940 0.060
I12.9 Hypertensive renal disease without renal failure
0.001 0.942 0.057
I70.00 Atherosclerosis of aorta (without gangrene)
0.001 0.946 0.053
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.954 0.046
I07.1 Tricuspid insufficiency
0.001 0.957 0.042
I71 Aortic aneurysm and dissection
0.001 0.959 0.040
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.961 0.039
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.965 0.035
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.965 0.035
E53 Deficiency of other B group vitamins
0.032 0.968 0.000
Z82.2 Family history of deafness and hearing loss
0.000 0.968 0.032
Z82.3 Family history of stroke
0.000 0.969 0.031
I71.8 Aortic aneurysm of unspecified site, ruptured
0.001 0.971 0.029
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.001 0.971 0.029
C32.0 Glottis
0.029 0.971 0.000
I78.1 Naevus, nonneoplastic
0.000 0.973 0.027
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.973 0.027
C32 Malignant neoplasm of larynx
0.027 0.973 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.974 0.026
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.001 0.974 0.025
H73.8 Other specified disorders of tympanic membrane
0.025 0.975 0.000
C32.9 Larynx, unspecified
0.024 0.976 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.001 0.976 0.023
E53.1 Pyridoxine deficiency
0.023 0.977 0.000
E53.0 Riboflavin deficiency
0.023 0.977 0.000
C32.2 Subglottis
0.023 0.977 0.000
Z82.1 Family history of blindness and visual loss
0.000 0.977 0.022
C32.1 Supraglottis
0.023 0.977 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.021 0.979 0.000
E50-E64 Other nutritional deficiencies
0.020 0.980 0.000
C32.8 Overlapping lesion of larynx
0.019 0.981 0.000
C32.3 Laryngeal cartilage
0.019 0.981 0.000
F60 Specific personality disorders
0.019 0.981 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.981 0.019
S90 Superficial injury of ankle and foot
0.019 0.981 0.000
F60.3 Emotionally unstable personality disorder
0.019 0.981 0.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.981 0.019
E78.0 Pure hypercholesterolaemia
0.000 0.982 0.018
F60.9 Personality disorder, unspecified
0.018 0.982 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.001 0.982 0.017
S90-S99 Injuries to the ankle and foot
0.018 0.982 0.000
E53.9 Vitamin B deficiency, unspecified
0.017 0.983 0.000
E61 Deficiency of other nutrient elements
0.017 0.983 0.000
E51 Thiamine deficiency
0.017 0.983 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.017 0.983 0.000
F60.7 Dependent personality disorder
0.017 0.983 0.000
S90.3 Contusion of other and unspecified parts of foot
0.016 0.984 0.000
S99 Other and unspecified injuries of ankle and foot
0.016 0.984 0.000
S90.1 Contusion of toe(s) without damage to nail
0.016 0.984 0.000
S92 Fracture of foot, except ankle
0.016 0.984 0.000
E56 Other vitamin deficiencies
0.016 0.984 0.000
S91 Open wound of ankle and foot
0.016 0.984 0.000
F60.5 Anankastic personality disorder
0.016 0.984 0.000
S90.0 Contusion of ankle
0.015 0.985 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.015 0.985 0.000
F60.2 Dissocial personality disorder
0.015 0.985 0.000
S90.8 Other superficial injuries of ankle and foot
0.015 0.985 0.000
F31.9 Bipolar affective disorder, unspecified
0.015 0.985 0.000
E51.2 Wernicke's encephalopathy
0.015 0.985 0.000
F60-F69 Disorders of adult personality and behaviour
0.015 0.985 0.000
I71.0 Dissection of aorta [any part]
0.001 0.985 0.014
E64 Sequelae of malnutrition and other nutritional deficiencies
0.014 0.986 0.000
E63 Other nutritional deficiencies
0.014 0.986 0.000
E50 Vitamin A deficiency
0.014 0.986 0.000
E60 Dietary zinc deficiency
0.014 0.986 0.000
E59 Dietary selenium deficiency
0.014 0.986 0.000
E52 Niacin deficiency [pellagra]
0.014 0.986 0.000
E61.1 Iron deficiency
0.014 0.986 0.000
F31 Bipolar affective disorder
0.014 0.986 0.000
S99.9 Unspecified injury of ankle and foot
0.014 0.986 0.000
E54 Ascorbic acid deficiency
0.014 0.986 0.000
F60.4 Histrionic personality disorder
0.014 0.986 0.000
F60.1 Schizoid personality disorder
0.014 0.986 0.000
S98 Traumatic amputation of ankle and foot
0.014 0.986 0.000
S90.7 Multiple superficial injuries of ankle and foot
0.014 0.986 0.000
S90.2 Contusion of toe(s) with damage to nail
0.014 0.986 0.000
E61.2 Magnesium deficiency
0.014 0.986 0.000
F60.8 Other specific personality disorders
0.014 0.986 0.000
S92.1 Fracture of talus
0.014 0.986 0.000
E58 Dietary calcium deficiency
0.013 0.987 0.000
S97 Crushing injury of ankle and foot
0.013 0.987 0.000
S91.1 Open wound of toe(s) without damage to nail
0.013 0.987 0.000
S91.3 Open wound of other parts of foot
0.013 0.987 0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level
0.013 0.987 0.000
S95 Injury of blood vessels at ankle and foot level
0.013 0.987 0.000
S94 Injury of nerves at ankle and foot level
0.013 0.987 0.000
F60.0 Paranoid personality disorder
0.013 0.987 0.000
F60.6 Anxious [avoidant] personality disorder
0.013 0.987 0.000
S99.8 Other specified injuries of ankle and foot
0.013 0.987 0.000
S92.4 Fracture of great toe
0.013 0.987 0.000
E56.1 Deficiency of vitamin K
0.013 0.987 0.000
F64 Gender identity disorders
0.013 0.987 0.000
S92.7 Multiple fractures of foot
0.013 0.987 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.013 0.987 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.987 0.013
S92.3 Fracture of metatarsal bone
0.013 0.987 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.987 0.013
I65.2 Occlusion and stenosis of carotid artery
0.000 0.987 0.013
E61.9 Deficiency of nutrient element, unspecified
0.012 0.988 0.000
E61.8 Deficiency of other specified nutrient elements
0.012 0.988 0.000
E61.7 Deficiency of multiple nutrient elements
0.012 0.988 0.000
E61.6 Vanadium deficiency
0.012 0.988 0.000
E61.5 Molybdenum deficiency
0.012 0.988 0.000
E61.4 Chromium deficiency
0.012 0.988 0.000
E61.3 Manganese deficiency
0.012 0.988 0.000
E61.0 Copper deficiency
0.012 0.988 0.000
E51.9 Thiamine deficiency, unspecified
0.012 0.988 0.000
E51.8 Other manifestations of thiamine deficiency
0.012 0.988 0.000
E51.1 Beriberi
0.012 0.988 0.000
F20.0 Paranoid schizophrenia
0.012 0.988 0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level
0.012 0.988 0.000
S92.10 Fracture of talus (closed)
0.012 0.988 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.012 0.988 0.000
F30-F39 Mood [affective] disorders
0.012 0.988 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.012 0.988 0.000
S99.7 Multiple injuries of ankle and foot
0.012 0.988 0.000
S92.2 Fracture of other tarsal bone(s)
0.012 0.988 0.000
E55 Vitamin D deficiency
0.011 0.988 0.000
E56.9 Vitamin deficiency, unspecified
0.011 0.988 0.000
E56.8 Deficiency of other vitamins
0.011 0.988 0.000
E56.0 Deficiency of vitamin E
0.011 0.988 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.012 0.988 0.000
S92.9 Fracture of foot, unspecified
0.011 0.988 0.000
S91.7 Multiple open wounds of ankle and foot
0.011 0.988 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.011 0.989 0.000
F64.0 Transsexualism
0.011 0.989 0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level
0.011 0.989 0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level
0.011 0.989 0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level
0.011 0.989 0.000
S91.0 Open wound of ankle
0.011 0.989 0.000
F33 Recurrent depressive disorder
0.011 0.989 0.000
S98.1 Traumatic amputation of one toe
0.011 0.989 0.000
F31.8 Other bipolar affective disorders
0.011 0.989 0.000
F69 Unspecified disorder of adult personality and behaviour
0.011 0.989 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.011 0.989 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.011 0.989 0.000
F68 Other disorders of adult personality and behaviour
0.011 0.989 0.000
F31.7 Bipolar affective disorder, currently in remission
0.011 0.989 0.000
S96.8 Injury of other muscles and tendons at ankle and foot level
0.011 0.989 0.000
E78.2 Mixed hyperlipidaemia
0.000 0.989 0.011
S93.0 Dislocation of ankle joint
0.011 0.989 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.011 0.989 0.000
F65 Disorders of sexual preference
0.011 0.989 0.000
F63 Habit and impulse disorders
0.011 0.989 0.000
S92.5 Fracture of other toe
0.011 0.989 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.989 0.011
E50.9 Vitamin A deficiency, unspecified
0.010 0.989 0.000
E50.8 Other manifestations of vitamin A deficiency
0.010 0.989 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.010 0.989 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.010 0.989 0.000
E50.5 Vitamin A deficiency with night blindness
0.010 0.989 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.010 0.989 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.010 0.989 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.010 0.989 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.010 0.989 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.010 0.989 0.000
E63.9 Nutritional deficiency, unspecified
0.010 0.989 0.000
E63.8 Other specified nutritional deficiencies
0.010 0.989 0.000
E63.1 Imbalance of constituents of food intake
0.010 0.989 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.010 0.989 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.010 0.989 0.000
E64.8 Sequelae of other nutritional deficiencies
0.010 0.989 0.000
E64.3 Sequelae of rickets
0.010 0.989 0.000
E64.2 Sequelae of vitamin C deficiency
0.010 0.989 0.000
E64.1 Sequelae of vitamin A deficiency
0.010 0.989 0.000
E64.0 Sequelae of protein-energy malnutrition
0.010 0.989 0.000
S91.2 Open wound of toe(s) with damage to nail
0.010 0.989 0.000
S92.70 Multiple fractures of foot (closed)
0.010 0.989 0.000
S92.41 Fracture of great toe (open)
0.010 0.990 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.001 0.990 0.010
S92.30 Fracture of metatarsal bone (closed)
0.010 0.990 0.000
S98.4 Traumatic amputation of foot, level unspecified
0.010 0.990 0.000
S98.3 Traumatic amputation of other parts of foot
0.010 0.990 0.000
S98.2 Traumatic amputation of two or more toes
0.010 0.990 0.000
S98.0 Traumatic amputation of foot at ankle level
0.010 0.990 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.990 0.010
F61 Mixed and other personality disorders
0.010 0.990 0.000
E78.6 Lipoprotein deficiency
0.000 0.990 0.010
F20 Schizophrenia
0.010 0.990 0.000
F34 Persistent mood [affective] disorders
0.010 0.990 0.000
S97.8 Crushing injury of other parts of ankle and foot
0.010 0.990 0.000
Chapter V Mental and behavioural disorders
0.010 0.990 0.000
S92.40 Fracture of great toe (closed)
0.010 0.990 0.000
S97.1 Crushing injury of toe(s)
0.010 0.990 0.000
S92.11 Fracture of talus (open)
0.010 0.990 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.010 0.990 0.000
S97.0 Crushing injury of ankle
0.010 0.990 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.010 0.990 0.000
I60-I69 Cerebrovascular diseases
0.000 0.990 0.010
S94.9 Injury of unspecified nerve at ankle and foot level
0.010 0.990 0.000
S94.8 Injury of other nerves at ankle and foot level
0.010 0.990 0.000
S94.7 Injury of multiple nerves at ankle and foot level
0.010 0.990 0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level
0.010 0.990 0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level
0.010 0.990 0.000
S94.1 Injury of medial plantar nerve
0.010 0.990 0.000
S94.0 Injury of lateral plantar nerve
0.010 0.990 0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level
0.010 0.990 0.000
S95.8 Injury of other blood vessels at ankle and foot level
0.010 0.990 0.000
S95.7 Injury of multiple blood vessels at ankle and foot level
0.010 0.990 0.000
S95.2 Injury of dorsal vein of foot
0.010 0.990 0.000
S95.1 Injury of plantar artery of foot
0.010 0.990 0.000
S95.0 Injury of dorsal artery of foot
0.010 0.990 0.000
F64.9 Gender identity disorder, unspecified
0.009 0.991 0.000
F64.8 Other gender identity disorders
0.009 0.991 0.000
F64.2 Gender identity disorder of childhood
0.009 0.991 0.000
F64.1 Dual-role transvestism
0.009 0.991 0.000
S92.71 Multiple fractures of foot (open)
0.009 0.991 0.000
S93.4 Sprain and strain of ankle
0.009 0.991 0.000
S93.6 Sprain and strain of other and unspecified parts of foot
0.009 0.991 0.000
S93.5 Sprain and strain of toe(s)
0.009 0.991 0.000
S92.31 Fracture of metatarsal bone (open)
0.009 0.991 0.000
F38 Other mood [affective] disorders
0.009 0.991 0.000
E78.3 Hyperchylomicronaemia
0.000 0.991 0.009
F33.1 Recurrent depressive disorder, current episode moderate
0.009 0.991 0.000
S93.2 Rupture of ligaments at ankle and foot level
0.009 0.991 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.009 0.991 0.000
E78.4 Other hyperlipidaemia
0.000 0.991 0.009
S93.3 Dislocation of other and unspecified parts of foot
0.008 0.991 0.000
F30 Manic episode
0.009 0.991 0.000
S92.20 Fracture of other tarsal bone(s) (closed)
0.008 0.991 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.008 0.991 0.000
S92.21 Fracture of other tarsal bone(s) (open)
0.008 0.991 0.000
S92.91 Fracture of foot, unspecified (open)
0.008 0.991 0.000
S92.90 Fracture of foot, unspecified (closed)
0.008 0.991 0.000
E55.0 Rickets, active
0.008 0.991 0.000
F20.8 Other schizophrenia
0.008 0.991 0.000
F33.8 Other recurrent depressive disorders
0.008 0.992 0.000
F39 Unspecified mood [affective] disorder
0.008 0.992 0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]
0.008 0.992 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.992 0.008
L05.0 Pilonidal cyst with abscess
0.000 0.992 0.008
F00-F09 Organic, including symptomatic, mental disorders
0.008 0.992 0.000
F34.0 Cyclothymia
0.008 0.992 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.008 0.992 0.000
F68.8 Other specified disorders of adult personality and behaviour
0.008 0.992 0.000
F68.0 Elaboration of physical symptoms for psychological reasons
0.008 0.992 0.000
F34.1 Dysthymia
0.008 0.992 0.000
S92.50 Fracture of other toe (closed)
0.008 0.992 0.000
F63.9 Habit and impulse disorder, unspecified
0.008 0.992 0.000
F63.8 Other habit and impulse disorders
0.008 0.992 0.000
F63.3 Trichotillomania
0.008 0.992 0.000
F63.2 Pathological stealing [kleptomania]
0.008 0.992 0.000
F63.1 Pathological fire-setting [pyromania]
0.008 0.992 0.000
F63.0 Pathological gambling
0.008 0.992 0.000
F65.9 Disorder of sexual preference, unspecified
0.008 0.992 0.000
F65.8 Other disorders of sexual preference
0.008 0.992 0.000
F65.6 Multiple disorders of sexual preference
0.008 0.992 0.000
F65.5 Sadomasochism
0.008 0.992 0.000
F65.4 Paedophilia
0.008 0.992 0.000
F65.3 Voyeurism
0.008 0.992 0.000
F65.2 Exhibitionism
0.008 0.992 0.000
F65.1 Fetishistic transvestism
0.008 0.992 0.000
F65.0 Fetishism
0.008 0.992 0.000
F66.9 Psychosexual development disorder, unspecified
0.008 0.992 0.000
F66.8 Other psychosexual development disorders
0.008 0.992 0.000
F66.2 Sexual relationship disorder
0.008 0.992 0.000
F66.1 Egodystonic sexual orientation
0.008 0.992 0.000
F66.0 Sexual maturation disorder
0.008 0.992 0.000
S92.0 Fracture of calcaneus
0.008 0.992 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.992 0.008
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.992 0.008
F02 Dementia in other diseases classified elsewhere
0.008 0.992 0.000
S93.1 Dislocation of toe(s)
0.008 0.992 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.008 0.992 0.000
L05.9 Pilonidal cyst without abscess
0.000 0.992 0.008
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.008 0.992 0.000
F20.6 Simple schizophrenia
0.007 0.992 0.000
F20.4 Postschizophrenic depression
0.007 0.992 0.000
F20.3 Undifferentiated schizophrenia
0.007 0.992 0.000
F20.2 Catatonic schizophrenia
0.007 0.992 0.000
F20.1 Hebephrenic schizophrenia
0.007 0.992 0.000
F33.9 Recurrent depressive disorder, unspecified
0.008 0.992 0.000
F70-F79 Mental retardation
0.007 0.992 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.007 0.992 0.000
F34.8 Other persistent mood [affective] disorders
0.007 0.992 0.000
F62.8 Other enduring personality changes
0.007 0.993 0.000
F62.1 Enduring personality change after psychiatric illness
0.007 0.993 0.000
F62.0 Enduring personality change after catastrophic experience
0.007 0.993 0.000
I65.1 Occlusion and stenosis of basilar artery
0.000 0.993 0.007
F20.5 Residual schizophrenia
0.007 0.993 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.993 0.007
F00 Dementia in Alzheimer's disease
0.007 0.993 0.000
J06.9 Acute upper respiratory infection, unspecified
0.007 0.993 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.007 0.993 0.000
F02.0 Dementia in Pick's disease
0.007 0.993 0.000
F80-F89 Disorders of psychological development
0.007 0.993 0.000
S93.40 Sprain of unspecified ligament of ankle
0.007 0.993 0.000
F21 Schizotypal disorder
0.007 0.993 0.000
L05 Pilonidal cyst
0.000 0.993 0.007
F30.9 Manic episode, unspecified
0.007 0.993 0.000
F99-F99 Unspecified mental disorder
0.007 0.993 0.000
S92.51 Fracture of other toe (open)
0.007 0.993 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.993 0.007
I62 Other nontraumatic intracranial haemorrhage
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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