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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0028
log Bayes Factor = 120.445
contains 7 variants:
rs115011993
lBF = 12.156
Chr 1 : 22,940,109
rs116821480
lBF = 12.384
Chr 2 : 165,547,969
rs79791727
lBF = 11.689
Chr 9 : 36,801,459
rs59541686
lBF = 7.316
Chr 9 : 71,815,966
rs17656127
lBF = 11.441
Chr18 : 47,026,826
rs78614307
lBF = 12.277
Chr19 : 5,790,540
rs78943781
lBF = 9.834
Chr19 : 32,443,306
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
S02 Fracture of skull and facial bones
1.000 0.000 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
1.000 0.000 0.000
Z50 Care involving use of rehabilitation procedures
1.000 0.000 0.000
I67 Other cerebrovascular diseases
1.000 0.000 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
1.000 0.000 0.000
L50-L54 Urticaria and erythema
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Z29 Need for other prophylactic measures
0.999 0.001 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.999 0.001 0.000
M24 Other specific joint derangements
0.999 0.001 0.000
I20.0 Unstable angina
0.999 0.001 0.000
Z50.1 Other physical therapy
0.999 0.001 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.999 0.001 0.000
Chapter XXII Codes for special purposes
0.999 0.001 0.000
G40-G47 Episodic and paroxysmal disorders
0.998 0.002 0.000
I35 Nonrheumatic aortic valve disorders
0.998 0.002 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.998 0.002 0.000
Z35 Supervision of high-risk pregnancy
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
S90-S99 Injuries to the ankle and foot
0.998 0.002 0.000
N17-N19 Renal failure
0.998 0.002 0.000
M80-M85 Disorders of bone density and structure
0.998 0.002 0.000
I77 Other disorders of arteries and arterioles
0.998 0.002 0.000
M86-M90 Other osteopathies
0.998 0.002 0.000
Z35.5 Supervision of elderly primigravida
0.997 0.003 0.000
G47 Sleep disorders
0.997 0.003 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.997 0.003 0.000
Z49 Care involving dialysis
0.997 0.003 0.000
L50 Urticaria
0.997 0.003 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.997 0.003 0.000
M84 Disorders of continuity of bone
0.997 0.003 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.996 0.004 0.000
I05-I09 Chronic rheumatic heart diseases
0.996 0.004 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
L20-L30 Dermatitis and eczema
0.996 0.004 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.996 0.004 0.000
G47.3 Sleep apnoea
0.994 0.006 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.994 0.006 0.000
U80 Agent resistant to penicillin and related antibiotics
0.994 0.006 0.000
L50.9 Urticaria, unspecified
0.993 0.007 0.000
N00-N08 Glomerular diseases
0.993 0.007 0.000
S02.0 Fracture of vault of skull
0.993 0.007 0.000
H55-H59 Other disorders of eye and adnexa
0.993 0.007 0.000
I77.6 Arteritis, unspecified
0.992 0.008 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.992 0.008 0.000
I35.1 Aortic (valve) insufficiency
0.991 0.009 0.000
G20-G26 Extrapyramidal and movement disorders
0.991 0.009 0.000
I20.1 Angina pectoris with documented spasm
0.991 0.009 0.000
I67.8 Other specified cerebrovascular diseases
0.991 0.009 0.000
I72 Other aneurysm
0.990 0.010 0.000
Y52 Agents primarily affecting the cardiovascular system
0.990 0.010 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.990 0.010 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.989 0.011 0.000
I05 Rheumatic mitral valve diseases
0.988 0.012 0.000
B35-B49 Mycoses
0.988 0.012 0.000
S02.00 Fracture of vault of skull (closed)
0.988 0.012 0.000
N05 Unspecified nephritic syndrome
0.988 0.012 0.000
I51 Complications and ill-defined descriptions of heart disease
0.988 0.012 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.987 0.013 0.000
S40-S49 Injuries to the shoulder and upper arm
0.987 0.013 0.000
U80.0 Penicillin resistant agent
0.986 0.014 0.000
Z29.1 Prophylactic immunotherapy
0.986 0.014 0.000
S10-S19 Injuries to the neck
0.985 0.015 0.000
I47 Paroxysmal tachycardia
0.984 0.016 0.000
I67.9 Cerebrovascular disease, unspecified
0.984 0.016 0.000
M21 Other acquired deformities of limbs
0.984 0.016 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.984 0.016 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.983 0.017 0.000
I21 Acute myocardial infarction
0.983 0.017 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.982 0.018 0.000
N18 Chronic renal failure
0.982 0.018 0.000
S70-S79 Injuries to the hip and thigh
0.981 0.019 0.000
Z75 Problems related to medical facilities and other health care
0.981 0.019 0.000
O60-O75 Complications of labour and delivery
0.981 0.019 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.980 0.020 0.000
Z50.5 Speech therapy
0.980 0.020 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.977 0.023 0.000
O44 Placenta praevia
0.976 0.024 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.976 0.024 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.975 0.025 0.000
Z29.0 Isolation
0.975 0.025 0.000
G70-G73 Diseases of myoneural junction and muscle
0.975 0.025 0.000
S20-S29 Injuries to the thorax
0.974 0.026 0.000
Z49.1 Extracorporeal dialysis
0.973 0.027 0.000
B15-B19 Viral hepatitis
0.973 0.027 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.973 0.027 0.000
O85-O92 Complications predominantly related to the puerperium
0.973 0.027 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.973 0.027 0.000
Z22 Carrier of infectious disease
0.972 0.028 0.000
I89.0 Lymphoedema, not elsewhere classified
0.972 0.028 0.000
M89 Other disorders of bone
0.972 0.028 0.000
E16 Other disorders of pancreatic internal secretion
0.972 0.028 0.000
M65-M68 Disorders of synovium and tendon
0.972 0.028 0.000
S70 Superficial injury of hip and thigh
0.971 0.029 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.970 0.030 0.000
S02.8 Fractures of other skull and facial bones
0.970 0.030 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.970 0.030 0.000
H55 Nystagmus and other irregular eye movements
0.969 0.031 0.000
N19 Unspecified renal failure
0.969 0.031 0.000
G25 Other extrapyramidal and movement disorders
0.969 0.031 0.000
N60-N64 Disorders of breast
0.968 0.032 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.968 0.032 0.000
Z32 Pregnancy examination and test
0.968 0.032 0.000
I72.4 Aneurysm of artery of lower extremity
0.967 0.033 0.000
Z57 Occupational exposure to risk-factors
0.965 0.035 0.000
M70-M79 Other soft tissue disorders
0.965 0.035 0.000
I71 Aortic aneurysm and dissection
0.965 0.035 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.964 0.036 0.000
E16.2 Hypoglycaemia, unspecified
0.964 0.036 0.000
S06 Intracranial injury
0.963 0.037 0.000
N61 Inflammatory disorders of breast
0.963 0.037 0.000
O72 Postpartum haemorrhage
0.962 0.038 0.000
Z74 Problems related to care-provider dependency
0.961 0.039 0.000
M24.1 Other articular cartilage disorders
0.961 0.039 0.000
I35.9 Aortic valve disorder, unspecified
0.961 0.039 0.000
Z22.3 Carrier of other specified bacterial diseases
0.960 0.040 0.000
N99-N99 Other disorders of the genitourinary system
0.959 0.041 0.000
V10-V19 Pedal cyclist injured in transport accident
0.958 0.042 0.000
Y57 Other and unspecified drugs and medicaments
0.957 0.043 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.956 0.044 0.000
Z57.2 Occupational exposure to dust
0.956 0.044 0.000
T82.1 Mechanical complication of cardiac electronic device
0.956 0.044 0.000
O32.2 Maternal care for transverse and oblique lie
0.955 0.045 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.955 0.045 0.000
X20-X29 Contact with venomous animals and plants
0.954 0.046 0.000
M60-M63 Disorders of muscles
0.954 0.046 0.000
E22 Hyperfunction of pituitary gland
0.954 0.046 0.000
I35.8 Other aortic valve disorders
0.954 0.046 0.000
L27 Dermatitis due to substances taken internally
0.953 0.047 0.000
N05.9 Unspecified
0.953 0.047 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.952 0.048 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.951 0.049 0.000
I67.2 Cerebral atherosclerosis
0.950 0.050 0.000
I51.6 Cardiovascular disease, unspecified
0.949 0.051 0.000
Chapter VIII Diseases of the ear and mastoid process
0.948 0.052 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.948 0.052 0.000
M88 Paget's disease of bone [osteitis deformans]
0.948 0.052 0.000
T79-T79 Certain early complications of trauma
0.948 0.052 0.000
I86 Varicose veins of other sites
0.948 0.052 0.000
Z12 Special screening examination for neoplasms
0.948 0.052 0.000
G90-G99 Other disorders of the nervous system
0.947 0.053 0.000
V80-V89 Other land transport accidents
0.947 0.053 0.000
I70 Atherosclerosis
0.946 0.054 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.946 0.054 0.000
A30-A49 Other bacterial diseases
0.945 0.055 0.000
I05.1 Rheumatic mitral insufficiency
0.945 0.055 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.945 0.055 0.000
S42 Fracture of shoulder and upper arm
0.945 0.055 0.000
Z04 Examination and observation for other reasons
0.944 0.056 0.000
Z74.2 Need for assistance at home and no other household member able to render care
0.944 0.056 0.000
Q00-Q07 Congenital malformations of the nervous system
0.944 0.056 0.000
I82 Other venous embolism and thrombosis
0.943 0.057 0.000
S02.4 Fracture of malar and maxillary bones
0.942 0.058 0.000
E29 Testicular dysfunction
0.942 0.058 0.000
Z49.2 Other dialysis
0.942 0.058 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.940 0.060 0.000
B37 Candidiasis
0.940 0.060 0.000
E24 Cushing's syndrome
0.939 0.061 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.939 0.061 0.000
M84.0 Malunion of fracture
0.939 0.061 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.938 0.062 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.938 0.062 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.938 0.062 0.000
O32.4 Maternal care for high head at term
0.937 0.063 0.000
S02.6 Fracture of mandible
0.936 0.064 0.000
B18 Chronic viral hepatitis
0.936 0.064 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.936 0.064 0.000
Z39 Postpartum care and examination
0.936 0.064 0.000
O86 Other puerperal infections
0.934 0.066 0.000
S91 Open wound of ankle and foot
0.934 0.066 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.934 0.066 0.000
M24.2 Disorder of ligament
0.934 0.066 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.933 0.067 0.000
O34.1 Maternal care for tumour of corpus uteri
0.933 0.067 0.000
N18.0 End-stage renal disease
0.932 0.068 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.932 0.068 0.000
T23 Burn and corrosion of wrist and hand
0.931 0.069 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.931 0.069 0.000
O43 Placental disorders
0.930 0.070 0.000
Y52.1 Calcium-channel blockers
0.929 0.071 0.000
I05.9 Mitral valve disease, unspecified
0.927 0.073 0.000
G72 Other myopathies
0.927 0.073 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.927 0.073 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.926 0.074 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.926 0.074 0.000
Z32.0 Pregnancy, not (yet) confirmed
0.925 0.075 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.925 0.075 0.000
Z42 Follow-up care involving plastic surgery
0.925 0.075 0.000
B37.8 Candidiasis of other sites
0.924 0.076 0.000
S05 Injury of eye and orbit
0.924 0.076 0.000
B50-B64 Protozoal diseases
0.924 0.076 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.924 0.076 0.000
O72.1 Other immediate postpartum haemorrhage
0.923 0.077 0.000
E10-E14 Diabetes mellitus
0.923 0.077 0.000
Z31 Procreative management
0.922 0.078 0.000
X23 Contact with hornets, wasps and bees
0.922 0.078 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.920 0.080 0.000
G30-G32 Other degenerative diseases of the nervous system
0.920 0.080 0.000
E14 Unspecified diabetes mellitus
0.919 0.081 0.000
G71 Primary disorders of muscles
0.919 0.081 0.000
I47.0 Reentry ventricular arrhythmia
0.919 0.081 0.000
E14.9 Without complications
0.919 0.081 0.000
M62 Other disorders of muscle
0.918 0.082 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.918 0.082 0.000
N18.2 Chronic kidney disease, stage 2
0.917 0.083 0.000
U51 Admission status on psychiatric patients
0.917 0.083 0.000
S99 Other and unspecified injuries of ankle and foot
0.917 0.083 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.916 0.084 0.000
I77.8 Other specified disorders of arteries and arterioles
0.916 0.084 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.916 0.084 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.916 0.084 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.915 0.085 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.915 0.085 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.914 0.086 0.000
Chapter V Mental and behavioural disorders
0.914 0.086 0.000
T86 Failure and rejection of transplanted organs and tissues
0.914 0.086 0.000
Q60-Q64 Congenital malformations of the urinary system
0.913 0.087 0.000
G20 Parkinson's disease
0.913 0.087 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.913 0.087 0.000
M88.9 Paget's disease of bone, unspecified
0.912 0.088 0.000
F30-F39 Mood [affective] disorders
0.912 0.088 0.000
Z04.9 Examination and observation for unspecified reason
0.912 0.088 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.912 0.088 0.000
L52 Erythema nodosum
0.912 0.088 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.912 0.088 0.000
I51.0 Cardiac septal defect, acquired
0.912 0.088 0.000
T66-T78 Other and unspecified effects of external causes
0.911 0.089 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.910 0.090 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.909 0.091 0.000
G25.3 Myoclonus
0.908 0.092 0.000
I60 Subarachnoid haemorrhage
0.907 0.093 0.000
M24.5 Contracture of joint
0.906 0.094 0.000
S06.4 Epidural haemorrhage
0.906 0.094 0.000
S70.0 Contusion of hip
0.906 0.094 0.000
M67 Other disorders of synovium and tendon
0.906 0.094 0.000
E27 Other disorders of adrenal gland
0.905 0.095 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.904 0.096 0.000
E34 Other endocrine disorders
0.904 0.096 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.903 0.097 0.000
S42.1 Fracture of scapula
0.902 0.098 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.902 0.098 0.000
G90 Disorders of autonomic nervous system
0.901 0.099 0.000
V40-V49 Car occupant injured in transport accident
0.900 0.100 0.000
O71 Other obstetric trauma
0.900 0.100 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.900 0.100 0.000
E29.1 Testicular hypofunction
0.900 0.100 0.000
G45.3 Amaurosis fugax
0.900 0.100 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.899 0.100 0.000
H57 Other disorders of eye and adnexa
0.900 0.100 0.000
M33 Dermatopolymyositis
0.899 0.101 0.000
N05.2 Diffuse membranous glomerulonephritis
0.899 0.101 0.000
S12 Fracture of neck
0.899 0.101 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.898 0.102 0.000
T91 Sequelae of injuries of neck and trunk
0.898 0.102 0.000
I87 Other disorders of veins
0.897 0.103 0.000
F33 Recurrent depressive disorder
0.897 0.103 0.000
S92 Fracture of foot, except ankle
0.897 0.103 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.896 0.104 0.000
I51.4 Myocarditis, unspecified
0.896 0.104 0.000
H04 Disorders of lachrymal system
0.895 0.105 0.000
G47.9 Sleep disorder, unspecified
0.895 0.105 0.000
T92 Sequelae of injuries of upper limb
0.895 0.105 0.000
M89.9 Disorder of bone, unspecified
0.894 0.106 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.893 0.107 0.000
M62.8 Other specified disorders of muscle
0.893 0.107 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.891 0.109 0.000
G41 Status epilepticus
0.891 0.109 0.000
S02.60 Fracture of mandible (closed)
0.891 0.109 0.000
M76 Enthesopathies of lower limb, excluding foot
0.891 0.109 0.000
H60-H62 Diseases of external ear
0.890 0.110 0.000
Z75.3 Unavailability and inaccessibility of health-care facilities
0.889 0.111 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.889 0.111 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.889 0.111 0.000
S93.1 Dislocation of toe(s)
0.888 0.112 0.000
I21.4 Acute subendocardial myocardial infarction
0.888 0.112 0.000
L29 Pruritus
0.887 0.113 0.000
Y57.8 Other drugs and medicaments
0.886 0.114 0.000
Z75.4 Unavailability and inaccessibility of other helping agencies
0.886 0.114 0.000
I82.2 Embolism and thrombosis of vena cava
0.885 0.115 0.000
W50-W64 Exposure to animate mechanical forces
0.885 0.115 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.885 0.115 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.885 0.115 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.885 0.115 0.000
B18.2 Chronic viral hepatitis C
0.884 0.116 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.883 0.117 0.000
O24 Diabetes mellitus in pregnancy
0.883 0.117 0.000
L51 Erythema multiforme
0.883 0.117 0.000
B99-B99 Other infectious diseases
0.883 0.117 0.000
O72.0 Third-stage haemorrhage
0.882 0.118 0.000
Z50.0 Cardiac rehabilitation
0.882 0.118 0.000
Z49.0 Preparatory care for dialysis
0.882 0.118 0.000
A46 Erysipelas
0.881 0.119 0.000
X23.9 Unspecified place
0.881 0.119 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.880 0.119 0.000
H20 Iridocyclitis
0.881 0.119 0.000
M79.2 Neuralgia and neuritis, unspecified
0.880 0.120 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.880 0.120 0.000
Z29.8 Other specified prophylactic measures
0.879 0.121 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.878 0.122 0.000
I72.0 Aneurysm of carotid artery
0.878 0.122 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.877 0.123 0.000
G62 Other polyneuropathies
0.877 0.123 0.000
Q23 Congenital malformations of aortic and mitral valves
0.876 0.124 0.000
Q80-Q89 Other congenital malformations
0.876 0.124 0.000
E28 Ovarian dysfunction
0.876 0.124 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.876 0.124 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.876 0.124 0.000
H65-H75 Diseases of middle ear and mastoid
0.874 0.126 0.000
N18.5 Chronic kidney disease, stage 5
0.874 0.126 0.000
G47.8 Other sleep disorders
0.874 0.126 0.000
T79.6 Traumatic ischaemia of muscle
0.874 0.126 0.000
M91-M94 Chondropathies
0.873 0.127 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.873 0.127 0.000
N18.1 Chronic kidney disease, stage 1
0.873 0.127 0.000
M21.2 Flexion deformity
0.873 0.127 0.000
S42.10 Fracture of scapula (closed)
0.872 0.128 0.000
O00-O08 Pregnancy with abortive outcome
0.872 0.128 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.871 0.129 0.000
L23 Allergic contact dermatitis
0.871 0.129 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.871 0.129 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.870 0.130 0.000
O23 Infections of genito-urinary tract in pregnancy
0.869 0.131 0.000
B59 Pneumocystosis
0.869 0.131 0.000
E24.2 Drug-induced Cushing's syndrome
0.868 0.132 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.868 0.132 0.000
O45 Premature separation of placenta [abruptio placentae]
0.865 0.135 0.000
O21 Excessive vomiting in pregnancy
0.865 0.135 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.865 0.135 0.000
S06.40 Epidural haemorrhage (without open intracranial wound)
0.865 0.135 0.000
O75.8 Other specified complications of labour and delivery
0.864 0.136 0.000
T13 Other injuries of lower limb, level unspecified
0.863 0.137 0.000
Z04.1 Examination and observation following transport accident
0.863 0.137 0.000
S91.0 Open wound of ankle
0.863 0.137 0.000
S22.3 Fracture of rib
0.862 0.138 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.861 0.139 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.861 0.139 0.000
N99.4 Postprocedural pelvic peritoneal adhesions
0.861 0.139 0.000
Z52 Donors of organs and tissues
0.860 0.140 0.000
S42.4 Fracture of lower end of humerus
0.859 0.141 0.000
M21.4 Flat foot [pes planus] (acquired)
0.859 0.141 0.000
H21 Other disorders of iris and ciliary body
0.859 0.141 0.000
S99.9 Unspecified injury of ankle and foot
0.859 0.141 0.000
Z04.5 Examination and observation following other inflicted injury
0.859 0.141 0.000
I47.1 Supraventricular tachycardia
0.859 0.141 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.858 0.142 0.000
E40-E46 Malnutrition
0.858 0.142 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.858 0.142 0.000
Q61 Cystic kidney disease
0.857 0.143 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.857 0.143 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.856 0.144 0.000
I86.8 Varicose veins of other specified sites
0.856 0.144 0.000
N18.8 Other chronic renal failure
0.856 0.144 0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.856 0.144 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.855 0.145 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.854 0.146 0.000
H50 Other strabismus
0.854 0.146 0.000
U80.1 Methicillin resistant agent
0.853 0.147 0.000
O43.8 Other placental disorders
0.853 0.147 0.000
G71.0 Muscular dystrophy
0.853 0.147 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.852 0.148 0.000
H74 Other disorders of middle ear and mastoid
0.852 0.148 0.000
B44 Aspergillosis
0.851 0.149 0.000
A40 Streptococcal septicaemia
0.851 0.149 0.000
M89.8 Other specified disorders of bone
0.851 0.149 0.000
I67.1 Cerebral aneurysm, nonruptured
0.851 0.149 0.000
S22.30 Fracture of rib (closed)
0.851 0.149 0.000
Z76 Persons encountering health services in other circumstances
0.851 0.149 0.000
F30 Manic episode
0.850 0.150 0.000
M65 Synovitis and tenosynovitis
0.850 0.150 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.850 0.150 0.000
B49 Unspecified mycosis
0.850 0.150 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.849 0.151 0.000
E27.8 Other specified disorders of adrenal gland
0.849 0.151 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.848 0.152 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.848 0.152 0.000
H18 Other disorders of cornea
0.848 0.152 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.847 0.153 0.000
I42 Cardiomyopathy
0.847 0.153 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.847 0.153 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.845 0.155 0.000
I87.8 Other specified disorders of veins
0.845 0.155 0.000
T21 Burn and corrosion of trunk
0.844 0.156 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.844 0.156 0.000
Z39.1 Care and examination of lactating mother
0.844 0.156 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.843 0.157 0.000
L50.0 Allergic urticaria
0.843 0.157 0.000
O71.4 Obstetric high vaginal laceration alone
0.843 0.157 0.000
S50-S59 Injuries to the elbow and forearm
0.842 0.158 0.000
M79.1 Myalgia
0.840 0.160 0.000
M05-M14 Inflammatory polyarthropathies
0.840 0.160 0.000
Y54.5 Other diuretics
0.839 0.161 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.839 0.161 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.837 0.163 0.000
I37 Pulmonary valve disorders
0.837 0.163 0.000
S02.3 Fracture of orbital floor
0.837 0.163 0.000
Z35.8 Supervision of other high-risk pregnancies
0.836 0.164 0.000
Y40 Systemic antibiotics
0.836 0.164 0.000
O86.4 Pyrexia of unknown origin following delivery
0.836 0.164 0.000
I74 Arterial embolism and thrombosis
0.835 0.165 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.835 0.165 0.000
M90 Osteopathies in diseases classified elsewhere
0.835 0.165 0.000
N05.1 Focal and segmental glomerular lesions
0.835 0.165 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.835 0.165 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.834 0.166 0.000
Y57.5 X-ray contrast media
0.834 0.166 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.834 0.166 0.000
Q76 Congenital malformations of spine and bony thorax
0.834 0.166 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.834 0.166 0.000
E22.1 Hyperprolactinaemia
0.834 0.166 0.000
N64 Other disorders of breast
0.833 0.167 0.000
N99.5 Malfunction of external stoma of urinary tract
0.833 0.167 0.000
E26 Hyperaldosteronism
0.833 0.167 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.833 0.167 0.000
I07 Rheumatic tricuspid valve diseases
0.832 0.168 0.000
L30 Other dermatitis
0.832 0.168 0.000
S40 Superficial injury of shoulder and upper arm
0.830 0.170 0.000
Z75.2 Other waiting period for investigation and treatment
0.830 0.170 0.000
Y46.4 Iminostilbenes
0.829 0.171 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.829 0.171 0.000
H05 Disorders of orbit
0.829 0.171 0.000
V18.0 Driver injured in nontraffic accident
0.829 0.171 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.829 0.171 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.829 0.171 0.000
Q27 Other congenital malformations of peripheral vascular system
0.828 0.172 0.000
M67.8 Other specified disorders of synovium and tendon
0.828 0.172 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.828 0.172 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.828 0.172 0.000
M89.0 Algoneurodystrophy
0.828 0.172 0.000
I71.0 Dissection of aorta [any part]
0.828 0.172 0.000
M33.1 Other dermatomyositis
0.827 0.173 0.000
S14 Injury of nerves and spinal cord at neck level
0.827 0.173 0.000
S29 Other and unspecified injuries of thorax
0.827 0.173 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.827 0.173 0.000
O86.0 Infection of obstetric surgical wound
0.827 0.173 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.826 0.174 0.000
S06.0 Concussion
0.826 0.174 0.000
S06.2 Diffuse brain injury
0.825 0.175 0.000
M24.23 Disorder of ligament (Forearm)
0.825 0.175 0.000
Q07 Other congenital malformations of nervous system
0.825 0.175 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.824 0.176 0.000
S41 Open wound of shoulder and upper arm
0.824 0.176 0.000
M76.6 Achilles tendinitis
0.823 0.177 0.000
Z32.1 Pregnancy confirmed
0.823 0.177 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.822 0.178 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.822 0.178 0.000
Z57.3 Occupational exposure to other air contaminants
0.822 0.178 0.000
O00 Ectopic pregnancy
0.822 0.178 0.000
T86.1 Kidney transplant failure and rejection
0.822 0.178 0.000
V20-V29 Motorcycle rider injured in transport accident
0.821 0.179 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.821 0.179 0.000
G60 Hereditary and idiopathic neuropathy
0.821 0.179 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.820 0.180 0.000
H60 Otitis externa
0.820 0.180 0.000
Q23.1 Congenital insufficiency of aortic valve
0.820 0.180 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.820 0.180 0.000
G62.8 Other specified polyneuropathies
0.820 0.180 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.820 0.180 0.000
I80 Phlebitis and thrombophlebitis
0.819 0.181 0.000
Q05 Spina bifida
0.819 0.181 0.000
Q24 Other congenital malformations of heart
0.818 0.182 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.818 0.182 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.818 0.182 0.000
Y54.3 Benzothiadiazine derivatives
0.818 0.182 0.000
O34.3 Maternal care for cervical incompetence
0.818 0.182 0.000
L53 Other erythematous conditions
0.817 0.183 0.000
S27 Injury of other and unspecified intrathoracic organs
0.817 0.183 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.816 0.184 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.816 0.184 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.816 0.184 0.000
I78 Diseases of capillaries
0.815 0.185 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.815 0.185 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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