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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115011993
log Bayes Factor = 12.156
Chromosome 1   position 22,940,109  (GRCh37) Explore rs115011993 on Ensembl!
Variant rs115011993 is part of Cluster X0028

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
I20 Angina pectoris
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
E86 Volume depletion
0.997 0.003 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.997 0.003 0.000
N17-N19 Renal failure
0.994 0.006 0.000
I67 Other cerebrovascular diseases
0.993 0.007 0.000
I30-I52 Other forms of heart disease
0.991 0.009 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.988 0.012 0.000
I67.8 Other specified cerebrovascular diseases
0.985 0.015 0.000
S00-S09 Injuries to the head
0.983 0.017 0.000
Chapter XXI Factors influencing health status and contact with health services
0.977 0.023 0.000
N17 Acute renal failure
0.977 0.023 0.000
I20.0 Unstable angina
0.976 0.024 0.000
Chapter I Certain infectious and parasitic diseases
0.975 0.025 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.968 0.032 0.000
N17.9 Acute renal failure, unspecified
0.961 0.039 0.000
I20.9 Angina pectoris, unspecified
0.961 0.039 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.956 0.044 0.000
L50-L54 Urticaria and erythema
0.951 0.049 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.949 0.051 0.000
I49 Other cardiac arrhythmias
0.947 0.053 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.946 0.054 0.000
S02 Fracture of skull and facial bones
0.945 0.055 0.000
Z03.8 Observation for other suspected diseases and conditions
0.945 0.055 0.000
N60-N64 Disorders of breast
0.944 0.056 0.000
I42 Cardiomyopathy
0.941 0.059 0.000
I05-I09 Chronic rheumatic heart diseases
0.933 0.067 0.000
L90 Atrophic disorders of skin
0.932 0.068 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.929 0.071 0.000
N20-N23 Urolithiasis
0.928 0.072 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.925 0.075 0.000
I35 Nonrheumatic aortic valve disorders
0.919 0.081 0.000
B95-B98 Bacterial, viral and other infectious agents
0.913 0.087 0.000
S20-S29 Injuries to the thorax
0.913 0.087 0.000
N63 Unspecified lump in breast
0.913 0.087 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.912 0.088 0.000
N18 Chronic renal failure
0.907 0.093 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.903 0.097 0.000
Z03.4 Observation for suspected myocardial infarction
0.902 0.098 0.000
S90-S99 Injuries to the ankle and foot
0.901 0.099 0.000
S09 Other and unspecified injuries of head
0.899 0.101 0.000
S70-S79 Injuries to the hip and thigh
0.898 0.102 0.000
L50 Urticaria
0.898 0.102 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.897 0.103 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.895 0.105 0.000
I25 Chronic ischaemic heart disease
0.895 0.105 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.892 0.108 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.888 0.112 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.887 0.113 0.000
L90.5 Scar conditions and fibrosis of skin
0.883 0.117 0.000
N19 Unspecified renal failure
0.882 0.118 0.000
I25.1 Atherosclerotic heart disease
0.881 0.119 0.000
L91 Hypertrophic disorders of skin
0.881 0.119 0.000
I49.0 Ventricular fibrillation and flutter
0.878 0.122 0.000
E83 Disorders of mineral metabolism
0.873 0.127 0.000
N18.9 Chronic renal failure, unspecified
0.873 0.127 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.873 0.127 0.000
Z12 Special screening examination for neoplasms
0.873 0.127 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.869 0.131 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.868 0.132 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.867 0.133 0.000
L89 Decubitus ulcer
0.864 0.136 0.000
I20.1 Angina pectoris with documented spasm
0.863 0.137 0.000
E20-E35 Disorders of other endocrine glands
0.861 0.139 0.000
N64 Other disorders of breast
0.859 0.141 0.000
Z98 Other postsurgical states
0.853 0.147 0.000
T82.1 Mechanical complication of cardiac electronic device
0.853 0.147 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.851 0.149 0.000
N30-N39 Other diseases of urinary system
0.850 0.150 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.849 0.151 0.000
I35.1 Aortic (valve) insufficiency
0.847 0.153 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.847 0.153 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.842 0.158 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.841 0.159 0.000
Z93 Artificial opening status
0.841 0.159 0.000
S09.9 Unspecified injury of head
0.839 0.161 0.000
B15-B19 Viral hepatitis
0.839 0.161 0.000
L57.0 Actinic keratosis
0.836 0.164 0.000
I22 Subsequent myocardial infarction
0.835 0.165 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.835 0.165 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.834 0.166 0.000
I65.2 Occlusion and stenosis of carotid artery
0.834 0.166 0.000
L20-L30 Dermatitis and eczema
0.834 0.166 0.000
I07 Rheumatic tricuspid valve diseases
0.832 0.168 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.831 0.169 0.000
I69 Sequelae of cerebrovascular disease
0.823 0.177 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.820 0.180 0.000
L50.9 Urticaria, unspecified
0.819 0.181 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.818 0.182 0.000
I33 Acute and subacute endocarditis
0.817 0.183 0.000
Z98.0 Intestinal bypass and anastomosis status
0.817 0.183 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.817 0.183 0.000
I42.0 Dilated cardiomyopathy
0.817 0.183 0.000
L91.8 Other hypertrophic disorders of skin
0.816 0.184 0.000
I60 Subarachnoid haemorrhage
0.816 0.184 0.000
I67.1 Cerebral aneurysm, nonruptured
0.815 0.185 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.813 0.187 0.000
S02.8 Fractures of other skull and facial bones
0.810 0.190 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.810 0.190 0.000
Z02 Examination and encounter for administrative purposes
0.809 0.191 0.000
I05 Rheumatic mitral valve diseases
0.808 0.192 0.000
E16 Other disorders of pancreatic internal secretion
0.808 0.192 0.000
S06 Intracranial injury
0.808 0.192 0.000
S92 Fracture of foot, except ankle
0.807 0.193 0.000
I47 Paroxysmal tachycardia
0.807 0.193 0.000
I63 Cerebral infarction
0.806 0.194 0.000
I24 Other acute ischaemic heart diseases
0.805 0.195 0.000
I74 Arterial embolism and thrombosis
0.803 0.197 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.799 0.201 0.000
S80-S89 Injuries to the knee and lower leg
0.798 0.202 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.793 0.207 0.000
Z90.3 Acquired absence of part of stomach
0.792 0.208 0.000
N21 Calculus of lower urinary tract
0.792 0.208 0.000
I36 Nonrheumatic tricuspid valve disorders
0.791 0.209 0.000
N23 Unspecified renal colic
0.789 0.211 0.000
S40-S49 Injuries to the shoulder and upper arm
0.788 0.212 0.000
N30 Cystitis
0.788 0.212 0.000
I20.8 Other forms of angina pectoris
0.788 0.212 0.000
L85 Other epidermal thickening
0.786 0.214 0.000
N64.8 Other specified disorders of breast
0.785 0.215 0.000
L89.1 Stage II decubitus ulcer
0.783 0.217 0.000
E40-E46 Malnutrition
0.783 0.217 0.000
B99-B99 Other infectious diseases
0.782 0.218 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.781 0.219 0.000
B50-B64 Protozoal diseases
0.780 0.219 0.000
L83 Acanthosis nigricans
0.780 0.220 0.000
N40-N51 Diseases of male genital organs
0.780 0.220 0.000
L50.0 Allergic urticaria
0.778 0.222 0.000
M20-M25 Other joint disorders
0.775 0.225 0.000
S02.5 Fracture of tooth
0.772 0.228 0.000
T79-T79 Certain early complications of trauma
0.772 0.228 0.000
E83.4 Disorders of magnesium metabolism
0.770 0.230 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.765 0.235 0.000
S02.0 Fracture of vault of skull
0.764 0.236 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.764 0.236 0.000
L52 Erythema nodosum
0.763 0.236 0.000
Z97 Presence of other devices
0.761 0.239 0.000
A30-A49 Other bacterial diseases
0.761 0.239 0.000
S70 Superficial injury of hip and thigh
0.760 0.240 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.760 0.240 0.000
I07.1 Tricuspid insufficiency
0.760 0.240 0.000
I42.2 Other hypertrophic cardiomyopathy
0.758 0.242 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.758 0.242 0.000
I49.8 Other specified cardiac arrhythmias
0.757 0.243 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.757 0.243 0.000
I37 Pulmonary valve disorders
0.756 0.244 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.756 0.244 0.000
M23 Internal derangement of knee
0.755 0.245 0.000
N61 Inflammatory disorders of breast
0.754 0.246 0.000
I67.9 Cerebrovascular disease, unspecified
0.752 0.248 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.752 0.248 0.000
E16.2 Hypoglycaemia, unspecified
0.751 0.249 0.000
I51 Complications and ill-defined descriptions of heart disease
0.751 0.249 0.000
I44 Atrioventricular and left bundle-branch block
0.751 0.249 0.000
S02.4 Fracture of malar and maxillary bones
0.750 0.250 0.000
N20 Calculus of kidney and ureter
0.749 0.251 0.000
N17.0 Acute renal failure with tubular necrosis
0.749 0.251 0.000
I42.8 Other cardiomyopathies
0.749 0.251 0.000
E27 Other disorders of adrenal gland
0.749 0.251 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.748 0.252 0.000
T85.2 Mechanical complication of intraocular lens
0.747 0.253 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.746 0.254 0.000
B35-B49 Mycoses
0.745 0.255 0.000
I74.5 Embolism and thrombosis of iliac artery
0.745 0.255 0.000
Z90.1 Acquired absence of breast(s)
0.745 0.255 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.743 0.257 0.000
I67.2 Cerebral atherosclerosis
0.743 0.257 0.000
I80 Phlebitis and thrombophlebitis
0.742 0.258 0.000
I61 Intracerebral haemorrhage
0.742 0.258 0.000
Z93.6 Other artificial openings of urinary tract status
0.741 0.259 0.000
Z93.5 Cystostomy status
0.741 0.259 0.000
Chapter VIII Diseases of the ear and mastoid process
0.741 0.259 0.000
E88 Other metabolic disorders
0.738 0.262 0.000
I49.5 Sick sinus syndrome
0.738 0.262 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.737 0.262 0.000
S05 Injury of eye and orbit
0.737 0.263 0.000
L29 Pruritus
0.736 0.264 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.735 0.265 0.000
I72 Other aneurysm
0.735 0.265 0.000
N18.4 Chronic kidney disease, stage 4
0.735 0.265 0.000
L93 Lupus erythematosus
0.734 0.266 0.000
S21 Open wound of thorax
0.734 0.266 0.000
I35.9 Aortic valve disorder, unspecified
0.733 0.267 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.733 0.267 0.000
S00 Superficial injury of head
0.733 0.267 0.000
E83.3 Disorders of phosphorus metabolism
0.731 0.269 0.000
T86 Failure and rejection of transplanted organs and tissues
0.731 0.269 0.000
I42.9 Cardiomyopathy, unspecified
0.728 0.272 0.000
S27 Injury of other and unspecified intrathoracic organs
0.728 0.272 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.727 0.273 0.000
S22.3 Fracture of rib
0.723 0.277 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.723 0.277 0.000
I26 Pulmonary embolism
0.723 0.277 0.000
N64.1 Fat necrosis of breast
0.723 0.277 0.000
I49.1 Atrial premature depolarisation
0.723 0.277 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.721 0.279 0.000
B18 Chronic viral hepatitis
0.720 0.280 0.000
L90.0 Lichen sclerosus et atrophicus
0.720 0.280 0.000
S10-S19 Injuries to the neck
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
I45 Other conduction disorders
0.716 0.284 0.000
E85 Amyloidosis
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
L10-L14 Bullous disorders
0.715 0.285 0.000
S92.0 Fracture of calcaneus
0.715 0.285 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.714 0.286 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.714 0.286 0.000
Z12.3 Special screening examination for neoplasm of breast
0.714 0.286 0.000
Q00-Q07 Congenital malformations of the nervous system
0.713 0.287 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.713 0.287 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.712 0.288 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.712 0.288 0.000
I67.5 Moyamoya disease
0.712 0.288 0.000
I67.4 Hypertensive encephalopathy
0.712 0.288 0.000
I67.3 Progressive vascular leukoencephalopathy
0.712 0.288 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.712 0.288 0.000
Z90.2 Acquired absence of lung [part of]
0.712 0.288 0.000
S72 Fracture of femur
0.712 0.288 0.000
Z22 Carrier of infectious disease
0.711 0.289 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.711 0.289 0.000
I52 Other heart disorders in diseases classified elsewhere
0.711 0.289 0.000
I48 Atrial fibrillation and flutter
0.711 0.289 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.711 0.289 0.000
I41 Myocarditis in diseases classified elsewhere
0.711 0.289 0.000
I40 Acute myocarditis
0.711 0.289 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.711 0.289 0.000
I32 Pericarditis in diseases classified elsewhere
0.711 0.289 0.000
T91 Sequelae of injuries of neck and trunk
0.710 0.290 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.709 0.291 0.000
L53 Other erythematous conditions
0.709 0.291 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.709 0.291 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.708 0.292 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.708 0.292 0.000
L94 Other localised connective tissue disorders
0.708 0.292 0.000
L87 Transepidermal elimination disorders
0.708 0.292 0.000
L88 Pyoderma gangrenosum
0.708 0.292 0.000
L86 Keratoderma in diseases classified elsewhere
0.708 0.292 0.000
L80 Vitiligo
0.708 0.292 0.000
L98.0 Pyogenic granuloma
0.708 0.292 0.000
S02.3 Fracture of orbital floor
0.707 0.293 0.000
M24 Other specific joint derangements
0.707 0.293 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.706 0.293 0.000
S08 Traumatic amputation of part of head
0.705 0.295 0.000
S07 Crushing injury of head
0.705 0.295 0.000
S04 Injury of cranial nerves
0.705 0.295 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.705 0.295 0.000
Z02.8 Other examinations for administrative purposes
0.704 0.296 0.000
Z90.0 Acquired absence of part of head and neck
0.704 0.296 0.000
N99-N99 Other disorders of the genitourinary system
0.702 0.298 0.000
Z95.2 Presence of prosthetic heart valve
0.702 0.298 0.000
B25-B34 Other viral diseases
0.702 0.298 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.701 0.299 0.000
N30.9 Cystitis, unspecified
0.701 0.299 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.701 0.299 0.000
N17.8 Other acute renal failure
0.700 0.300 0.000
N17.2 Acute renal failure with medullary necrosis
0.700 0.300 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.700 0.300 0.000
Z00.0 General medical examination
0.700 0.300 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.699 0.301 0.000
B65-B83 Helminthiases
0.699 0.301 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.699 0.301 0.000
A75-A79 Rickettsioses
0.699 0.301 0.000
A70-A74 Other diseases caused by chlamydiae
0.699 0.301 0.000
A65-A69 Other spirochaetal diseases
0.699 0.301 0.000
A20-A28 Certain zoonotic bacterial diseases
0.699 0.301 0.000
A15-A19 Tuberculosis
0.699 0.301 0.000
I51.9 Heart disease, unspecified
0.698 0.302 0.000
Z00.4 General psychiatric examination, not elsewhere classified
0.697 0.303 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.697 0.303 0.000
Z00.5 Examination of potential donor of organ and tissue
0.695 0.305 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.694 0.306 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.694 0.306 0.000
L98.5 Mucinosis of skin
0.694 0.306 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.694 0.306 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.694 0.306 0.000
L98.1 Factitial dermatitis
0.694 0.306 0.000
T66-T78 Other and unspecified effects of external causes
0.694 0.306 0.000
S99 Other and unspecified injuries of ankle and foot
0.694 0.306 0.000
Chapter XXII Codes for special purposes
0.694 0.306 0.000
S02.2 Fracture of nasal bones
0.693 0.307 0.000
I33.0 Acute and subacute infective endocarditis
0.693 0.307 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.693 0.307 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.691 0.309 0.000
N18.2 Chronic kidney disease, stage 2
0.690 0.310 0.000
N48 Other disorders of penis
0.690 0.310 0.000
I49.4 Other and unspecified premature depolarisation
0.690 0.310 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.690 0.310 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.688 0.312 0.000
S02.1 Fracture of base of skull
0.688 0.312 0.000
M65-M68 Disorders of synovium and tendon
0.688 0.312 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.688 0.312 0.000
Z29 Need for other prophylactic measures
0.688 0.312 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.687 0.313 0.000
I49.3 Ventricular premature depolarisation
0.687 0.313 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.686 0.314 0.000
Z10 Routine general health check-up of defined subpopulation
0.685 0.314 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.685 0.314 0.000
E78.0 Pure hypercholesterolaemia
0.683 0.317 0.000
N36 Other disorders of urethra
0.683 0.317 0.000
I05.9 Mitral valve disease, unspecified
0.683 0.317 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.683 0.317 0.000
L54 Erythema in diseases classified elsewhere
0.682 0.318 0.000
L51 Erythema multiforme
0.682 0.318 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.681 0.319 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.680 0.320 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.680 0.320 0.000
Z03.0 Observation for suspected tuberculosis
0.680 0.320 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.680 0.320 0.000
I82 Other venous embolism and thrombosis
0.680 0.320 0.000
E83.5 Disorders of calcium metabolism
0.680 0.320 0.000
I49.2 Junctional premature depolarisation
0.679 0.321 0.000
S06.0 Concussion
0.679 0.321 0.000
T87 Complications peculiar to reattachment and amputation
0.678 0.322 0.000
M23.8 Other internal derangements of knee
0.678 0.322 0.000
S02.7 Multiple fractures involving skull and facial bones
0.677 0.322 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.677 0.323 0.000
E78.8 Other disorders of lipoprotein metabolism
0.677 0.323 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.675 0.325 0.000
I42.6 Alcoholic cardiomyopathy
0.675 0.325 0.000
I42.5 Other restrictive cardiomyopathy
0.675 0.325 0.000
I42.4 Endocardial fibroelastosis
0.675 0.325 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.675 0.325 0.000
I28 Other diseases of pulmonary vessels
0.674 0.326 0.000
S22.30 Fracture of rib (closed)
0.674 0.326 0.000
L28 Lichen simplex chronicus and prurigo
0.673 0.327 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.673 0.327 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.673 0.327 0.000
T51 Toxic effect of alcohol
0.672 0.328 0.000
S90 Superficial injury of ankle and foot
0.671 0.328 0.000
T93 Sequelae of injuries of lower limb
0.669 0.331 0.000
I09 Other rheumatic heart diseases
0.669 0.331 0.000
I06 Rheumatic aortic valve diseases
0.669 0.331 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.669 0.331 0.000
E22 Hyperfunction of pituitary gland
0.669 0.331 0.000
L90.9 Atrophic disorder of skin, unspecified
0.668 0.331 0.000
L90.8 Other atrophic disorders of skin
0.668 0.331 0.000
L90.6 Striae atrophicae
0.668 0.331 0.000
L90.4 Acrodermatitis chronica atrophicans
0.668 0.331 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.668 0.331 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.668 0.331 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.668 0.331 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.668 0.332 0.000
I08 Multiple valve diseases
0.668 0.332 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.667 0.333 0.000
I31 Other diseases of pericardium
0.667 0.333 0.000
N18.0 End-stage renal disease
0.667 0.333 0.000
T98 Sequelae of other and unspecified effects of external causes
0.666 0.334 0.000
N21.0 Calculus in bladder
0.666 0.334 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.666 0.334 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.665 0.334 0.000
Z94 Transplanted organ and tissue status
0.665 0.335 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.664 0.336 0.000
M25 Other joint disorders, not elsewhere classified
0.664 0.336 0.000
S79 Other and unspecified injuries of hip and thigh
0.664 0.336 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.663 0.337 0.000
L58 Radiodermatitis
0.663 0.337 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.663 0.337 0.000
L55 Sunburn
0.663 0.337 0.000
A46 Erysipelas
0.663 0.337 0.000
I49.9 Cardiac arrhythmia, unspecified
0.662 0.338 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.662 0.338 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.662 0.338 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.659 0.340 0.000
I44.1 Atrioventricular block, second degree
0.659 0.341 0.000
I35.8 Other aortic valve disorders
0.659 0.341 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.658 0.342 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.657 0.343 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.656 0.344 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.656 0.344 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.654 0.345 0.000
S26 Injury of heart
0.654 0.345 0.000
S25 Injury of blood vessels of thorax
0.654 0.345 0.000
S24 Injury of nerves and spinal cord at thorax level
0.654 0.345 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.654 0.345 0.000
S86 Injury of muscle and tendon at lower leg level
0.654 0.346 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.654 0.346 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.654 0.346 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.654 0.346 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.654 0.346 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.653 0.347 0.000
N25-N29 Other disorders of kidney and ureter
0.653 0.347 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.653 0.347 0.000
M80-M85 Disorders of bone density and structure
0.652 0.348 0.000
A80-A89 Viral infections of the central nervous system
0.651 0.348 0.000
S02.6 Fracture of mandible
0.651 0.349 0.000
S20 Superficial injury of thorax
0.651 0.349 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.651 0.349 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.650 0.349 0.000
M23.3 Other meniscus derangements
0.651 0.349 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.650 0.350 0.000
N30.0 Acute cystitis
0.650 0.350 0.000
Z97.8 Presence of other specified devices
0.650 0.350 0.000
N18.8 Other chronic renal failure
0.650 0.350 0.000
N18.1 Chronic kidney disease, stage 1
0.650 0.350 0.000
M35 Other systemic involvement of connective tissue
0.649 0.351 0.000
S02.50 Fracture of tooth (closed)
0.648 0.351 0.000
S92.00 Fracture of calcaneus (closed)
0.648 0.352 0.000
I81 Portal vein thrombosis
0.647 0.353 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.647 0.353 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.647 0.353 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.647 0.353 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.647 0.353 0.000
I65.1 Occlusion and stenosis of basilar artery
0.647 0.353 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.647 0.353 0.000
E29 Testicular dysfunction
0.647 0.353 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.646 0.354 0.000
S29 Other and unspecified injuries of thorax
0.646 0.354 0.000
S98 Traumatic amputation of ankle and foot
0.646 0.354 0.000
S97 Crushing injury of ankle and foot
0.646 0.354 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.646 0.354 0.000
S95 Injury of blood vessels at ankle and foot level
0.646 0.354 0.000
S94 Injury of nerves at ankle and foot level
0.646 0.354 0.000
B16 Acute hepatitis B
0.645 0.355 0.000
S09.8 Other specified injuries of head
0.645 0.355 0.000
S09.7 Multiple injuries of head
0.645 0.355 0.000
S09.2 Traumatic rupture of ear drum
0.645 0.355 0.000
S09.1 Injury of muscle and tendon of head
0.645 0.355 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.645 0.355 0.000
B99 Other and unspecified infectious diseases
0.644 0.356 0.000
S78 Traumatic amputation of hip and thigh
0.644 0.356 0.000
S77 Crushing injury of hip and thigh
0.644 0.356 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.644 0.356 0.000
S75 Injury of blood vessels at hip and thigh level
0.644 0.356 0.000
S74 Injury of nerves at hip and thigh level
0.644 0.356 0.000
S71 Open wound of hip and thigh
0.644 0.356 0.000
L50.8 Other urticaria
0.644 0.356 0.000
L50.6 Contact urticaria
0.644 0.356 0.000
L50.5 Cholinergic urticaria
0.644 0.356 0.000
L50.4 Vibratory urticaria
0.644 0.356 0.000
L50.3 Dermatographic urticaria
0.644 0.356 0.000
L50.2 Urticaria due to cold and heat
0.644 0.356 0.000
L50.1 Idiopathic urticaria
0.644 0.356 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.644 0.356 0.000
I05.0 Mitral stenosis
0.644 0.356 0.000
N39 Other disorders of urinary system
0.643 0.357 0.000
Z81 Family history of mental and behavioural disorders
0.643 0.357 0.000
Z95.3 Presence of xenogenic heart valve
0.643 0.357 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.642 0.358 0.000
I86 Varicose veins of other sites
0.642 0.358 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.642 0.358 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.642 0.358 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.642 0.358 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.642 0.358 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.642 0.358 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.642 0.358 0.000
T36 Poisoning by systemic antibiotics
0.642 0.358 0.000
I25.6 Silent myocardial ischaemia
0.641 0.358 0.000
I25.4 Coronary artery aneurysm
0.641 0.358 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.641 0.358 0.000
B59 Pneumocystosis
0.641 0.359 0.000
Z84 Family history of other conditions
0.641 0.359 0.000
I69.3 Sequelae of cerebral infarction
0.641 0.359 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.640 0.360 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.639 0.361 0.000
T14 Injury of unspecified body region
0.639 0.361 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.638 0.362 0.000
T90 Sequelae of injuries of head
0.638 0.362 0.000
I87 Other disorders of veins
0.638 0.362 0.000
T13 Other injuries of lower limb, level unspecified
0.637 0.363 0.000
I45.6 Preexcitation syndrome
0.636 0.363 0.000
H60-H62 Diseases of external ear
0.636 0.364 0.000
E15 Nondiabetic hypoglycaemic coma
0.636 0.364 0.000
Z22.3 Carrier of other specified bacterial diseases
0.635 0.365 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.634 0.365 0.000
S02.00 Fracture of vault of skull (closed)
0.634 0.366 0.000
T82.3 Mechanical complication of other vascular grafts
0.634 0.366 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.633 0.366 0.000
B18.2 Chronic viral hepatitis C
0.633 0.367 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.632 0.368 0.000
M24.1 Other articular cartilage disorders
0.632 0.368 0.000
L91.9 Hypertrophic disorder of skin, unspecified
0.631 0.368 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.631 0.369 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.631 0.369 0.000
N39.0 Urinary tract infection, site not specified
0.631 0.369 0.000
L85.8 Other specified epidermal thickening
0.630 0.370 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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