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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs216196
log Bayes Factor = 8.07442
Chromosome 17   position 2,202,943  (GRCh37) Explore rs216196 on Ensembl!
Variant rs216196 is part of Cluster X0002

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.001 0.999
I20.9 Angina pectoris, unspecified
0.000 0.003 0.997
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.012 0.988
I20.8 Other forms of angina pectoris
0.000 0.025 0.975
I21 Acute myocardial infarction
0.000 0.034 0.966
I25.5 Ischaemic cardiomyopathy
0.000 0.050 0.950
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.059 0.941
I22 Subsequent myocardial infarction
0.000 0.062 0.938
I25.3 Aneurysm of heart
0.000 0.074 0.926
I22.8 Subsequent myocardial infarction of other sites
0.000 0.129 0.871
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.146 0.854
I24 Other acute ischaemic heart diseases
0.000 0.160 0.840
I21.4 Acute subendocardial myocardial infarction
0.000 0.170 0.830
I20.0 Unstable angina
0.000 0.223 0.777
I25.4 Coronary artery aneurysm
0.000 0.225 0.775
I24.8 Other forms of acute ischaemic heart disease
0.000 0.232 0.768
I23 Certain current complications following acute myocardial infarction
0.000 0.234 0.766
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.235 0.765
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.237 0.762
I25.2 Old myocardial infarction
0.000 0.257 0.743
I21.9 Acute myocardial infarction, unspecified
0.000 0.258 0.742
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.307 0.693
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.336 0.664
I23.8 Other current complications following acute myocardial infarction
0.000 0.402 0.598
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.432 0.568
I24.1 Dressler's syndrome
0.000 0.447 0.553
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.451 0.549
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.451 0.549
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.451 0.549
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.451 0.549
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.451 0.549
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.451 0.549
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.451 0.549
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.459 0.541
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.496 0.503
I21.3 Acute transmural myocardial infarction of unspecified site
0.001 0.545 0.455
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.581 0.419
I20.1 Angina pectoris with documented spasm
0.000 0.591 0.408
I72 Other aneurysm
0.000 0.846 0.154
I72.4 Aneurysm of artery of lower extremity
0.000 0.852 0.148
I72.3 Aneurysm of iliac artery
0.000 0.856 0.144
I72.8 Aneurysm of other specified arteries
0.000 0.856 0.144
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.866 0.134
Chapter IX Diseases of the circulatory system
0.000 0.869 0.131
I72.2 Aneurysm of renal artery
0.000 0.871 0.129
I72.9 Aneurysm of unspecified site
0.000 0.876 0.124
I74 Arterial embolism and thrombosis
0.000 0.883 0.117
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.889 0.110
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.889 0.110
I70 Atherosclerosis
0.000 0.891 0.109
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.894 0.106
I70.0 Atherosclerosis of aorta
0.000 0.897 0.103
I72.1 Aneurysm of artery of upper extremity
0.000 0.898 0.102
I74.5 Embolism and thrombosis of iliac artery
0.000 0.901 0.099
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.901 0.099
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.901 0.099
I00-I02 Acute rheumatic fever
0.000 0.902 0.098
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.903 0.097
I72.0 Aneurysm of carotid artery
0.000 0.907 0.093
I71 Aortic aneurysm and dissection
0.000 0.907 0.093
I74.8 Embolism and thrombosis of other arteries
0.000 0.909 0.091
I05-I09 Chronic rheumatic heart diseases
0.000 0.911 0.089
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.912 0.088
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.912 0.088
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.912 0.088
I95 Hypotension
0.000 0.916 0.084
I07 Rheumatic tricuspid valve diseases
0.000 0.918 0.082
I95.2 Hypotension due to drugs
0.000 0.920 0.080
I95.1 Orthostatic hypotension
0.000 0.920 0.080
I70.9 Generalised and unspecified atherosclerosis
0.000 0.922 0.078
I70.8 Atherosclerosis of other arteries
0.000 0.922 0.078
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.922 0.078
I07.1 Tricuspid insufficiency
0.000 0.923 0.077
I79.1 Aortitis in diseases classified elsewhere
0.000 0.924 0.076
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.924 0.076
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.924 0.076
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.924 0.076
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.924 0.075
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.926 0.074
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.926 0.074
I00 Rheumatic fever without mention of heart involvement
0.000 0.926 0.074
I71.0 Dissection of aorta [any part]
0.000 0.928 0.072
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.928 0.072
I02 Rheumatic chorea
0.000 0.930 0.070
I01 Rheumatic fever with heart involvement
0.000 0.930 0.070
I70.1 Atherosclerosis of renal artery
0.000 0.932 0.068
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.933 0.067
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.933 0.067
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.933 0.067
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.933 0.067
I09 Other rheumatic heart diseases
0.000 0.933 0.066
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.934 0.066
I95.0 Idiopathic hypotension
0.000 0.938 0.062
I06 Rheumatic aortic valve diseases
0.000 0.939 0.061
I78 Diseases of capillaries
0.000 0.940 0.060
I07.9 Tricuspid valve disease, unspecified
0.000 0.941 0.059
I07.8 Other tricuspid valve diseases
0.000 0.941 0.059
I07.2 Tricuspid stenosis with insufficiency
0.000 0.941 0.059
I07.0 Tricuspid stenosis
0.000 0.941 0.059
I95.8 Other hypotension
0.000 0.941 0.059
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.943 0.056
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.943 0.056
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.944 0.056
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.944 0.055
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.945 0.055
I26 Pulmonary embolism
0.000 0.945 0.055
I28 Other diseases of pulmonary vessels
0.000 0.946 0.054
M43.16 Spondylolisthesis (Lumbar region)
0.000 0.947 0.053
I08 Multiple valve diseases
0.000 0.948 0.052
I80 Phlebitis and thrombophlebitis
0.000 0.949 0.051
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.949 0.050
I01.8 Other acute rheumatic heart disease
0.000 0.949 0.050
I01.2 Acute rheumatic myocarditis
0.000 0.949 0.050
I01.1 Acute rheumatic endocarditis
0.000 0.949 0.050
I01.0 Acute rheumatic pericarditis
0.000 0.949 0.050
I02.9 Rheumatic chorea without heart involvement
0.000 0.949 0.050
I02.0 Rheumatic chorea with heart involvement
0.000 0.949 0.050
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.949 0.051
I09.9 Rheumatic heart disease, unspecified
0.000 0.950 0.050
I10-I15 Hypertensive diseases
0.000 0.951 0.049
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.951 0.049
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.951 0.049
I99 Other and unspecified disorders of circulatory system
0.000 0.952 0.048
I09.8 Other specified rheumatic heart diseases
0.000 0.952 0.048
I09.2 Chronic rheumatic pericarditis
0.000 0.952 0.048
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.952 0.048
I09.0 Rheumatic myocarditis
0.000 0.952 0.048
I08.0 Disorders of both mitral and aortic valves
0.000 0.952 0.048
I86 Varicose veins of other sites
0.000 0.954 0.046
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.955 0.045
I78.8 Other diseases of capillaries
0.000 0.955 0.045
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.955 0.045
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.956 0.044
I06.8 Other rheumatic aortic valve diseases
0.000 0.956 0.044
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.956 0.044
I06.1 Rheumatic aortic insufficiency
0.000 0.956 0.044
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.956 0.044
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.956 0.044
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.957 0.043
I78.9 Disease of capillaries, unspecified
0.000 0.957 0.043
I81 Portal vein thrombosis
0.000 0.958 0.042
I86.4 Gastric varices
0.000 0.958 0.042
I28.8 Other specified diseases of pulmonary vessels
0.000 0.958 0.042
I06.0 Rheumatic aortic stenosis
0.000 0.958 0.041
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.959 0.041
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.959 0.041
I11 Hypertensive heart disease
0.000 0.960 0.039
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.961 0.039
I28.1 Aneurysm of pulmonary artery
0.000 0.961 0.039
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.961 0.039
I86.8 Varicose veins of other specified sites
0.000 0.961 0.039
I08.9 Multiple valve disease, unspecified
0.000 0.961 0.039
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.961 0.039
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.962 0.038
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.963 0.037
I86.2 Pelvic varices
0.000 0.964 0.036
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.964 0.036
I13 Hypertensive heart and renal disease
0.000 0.964 0.035
I15 Secondary hypertension
0.000 0.965 0.035
I88 Nonspecific lymphadenitis
0.000 0.965 0.035
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.965 0.035
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.966 0.034
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.966 0.033
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.967 0.033
I77 Other disorders of arteries and arterioles
0.000 0.967 0.033
I86.0 Sublingual varices
0.000 0.967 0.033
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.967 0.032
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.967 0.032
I98.0 Cardiovascular syphilis
0.000 0.967 0.032
I86.3 Vulval varices
0.000 0.968 0.032
I08.8 Other multiple valve diseases
0.000 0.969 0.031
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.969 0.031
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.970 0.029
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.971 0.029
I15.1 Hypertension secondary to other renal disorders
0.000 0.971 0.029
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.973 0.027
I77.2 Rupture of artery
0.000 0.973 0.027
I12 Hypertensive renal disease
0.000 0.974 0.026
M43.1 Spondylolisthesis
0.000 0.974 0.026
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.974 0.026
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.974 0.026
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.974 0.026
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.974 0.026
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.974 0.026
I15.8 Other secondary hypertension
0.000 0.974 0.025
I15.2 Hypertension secondary to endocrine disorders
0.000 0.974 0.025
I15.0 Renovascular hypertension
0.000 0.974 0.025
I88.8 Other nonspecific lymphadenitis
0.000 0.974 0.025
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.974 0.025
I77.8 Other specified disorders of arteries and arterioles
0.000 0.975 0.025
I77.1 Stricture of artery
0.000 0.975 0.025
I77.5 Necrosis of artery
0.000 0.976 0.024
I77.4 Coeliac artery compression syndrome
0.000 0.976 0.024
I77.3 Arterial fibromuscular dysplasia
0.000 0.976 0.024
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.976 0.024
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.976 0.023
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.977 0.023
I05 Rheumatic mitral valve diseases
0.000 0.977 0.023
I89.1 Lymphangitis
0.000 0.977 0.023
Z95.1 Presence of aortocoronary bypass graft
0.000 0.978 0.022
D47.3 Essential (haemorrhagic) thrombocythaemia
0.022 0.978 0.000
I97.0 Postcardiotomy syndrome
0.000 0.979 0.021
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.979 0.021
I86.1 Scrotal varices
0.000 0.979 0.021
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.979 0.021
I73 Other peripheral vascular diseases
0.000 0.979 0.021
T36-T50 Poisoning by drugs, medicaments and biological substances
0.021 0.979 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.021 0.979 0.000
I15.9 Seconday hypertension, unspecified
0.000 0.980 0.020
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.980 0.020
M43.19 Spondylolisthesis (Site unspecified)
0.000 0.980 0.020
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.020 0.980 0.000
M43.12 Spondylolisthesis (Cervical region)
0.000 0.981 0.019
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.981 0.019
F33.9 Recurrent depressive disorder, unspecified
0.000 0.981 0.019
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.019 0.981 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.000 0.981 0.019
M43.15 Spondylolisthesis (Thoracolumbar region)
0.000 0.981 0.019
M43.14 Spondylolisthesis (Thoracic region)
0.000 0.981 0.019
M43.13 Spondylolisthesis (Cervicothoracic region)
0.000 0.981 0.019
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.000 0.981 0.019
M43.10 Spondylolisthesis (Multiple sites in spine)
0.000 0.981 0.019
T46 Poisoning by agents primarily affecting the cardiovascular system
0.019 0.981 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.018 0.982 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.018 0.982 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.018 0.982 0.000
I95.9 Hypotension, unspecified
0.000 0.982 0.018
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.018 0.982 0.000
I97.1 Other functional disturbances following cardiac surgery
0.000 0.982 0.017
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.982 0.017
T43.0 Tricyclic and tetracyclic antidepressants
0.018 0.982 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.017 0.983 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.983 0.017
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.017 0.983 0.000
I77.0 Arteriovenous fistula, acquired
0.000 0.983 0.017
I27 Other pulmonary heart diseases
0.000 0.983 0.017
I05.8 Other mitral valve diseases
0.000 0.983 0.017
I85 Oesophageal varices
0.003 0.983 0.014
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.017 0.983 0.000
T46.1 Calcium-channel blockers
0.017 0.983 0.000
T43.6 Psychostimulants with abuse potential
0.017 0.983 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.016 0.984 0.000
T36 Poisoning by systemic antibiotics
0.016 0.984 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.016 0.984 0.000
T38.1 Thyroid hormones and substitutes
0.016 0.984 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.016 0.984 0.000
I83 Varicose veins of lower extremities
0.000 0.984 0.016
I82 Other venous embolism and thrombosis
0.000 0.985 0.015
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.015 0.985 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.015 0.985 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.015 0.985 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.985 0.015
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.015 0.985 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.015 0.985 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.015 0.985 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.015 0.985 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.015 0.985 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.015 0.985 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.015 0.985 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.015 0.985 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.015 0.985 0.000
T44.0 Anticholinesterase agents
0.015 0.985 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.015 0.985 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.015 0.985 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.015 0.985 0.000
M43 Other deforming dorsopathies
0.000 0.985 0.015
T43.9 Psychotropic drug, unspecified
0.014 0.985 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.014 0.985 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.014 0.985 0.000
I87 Other disorders of veins
0.000 0.986 0.014
T38.9 Other and unspecified hormone antagonists
0.014 0.986 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.014 0.986 0.000
T38.7 Androgens and anabolic congeners
0.014 0.986 0.000
T38.5 Other oestrogens and progestogens
0.014 0.986 0.000
T38.4 Oral contraceptives
0.014 0.986 0.000
T38.2 Antithyroid drugs
0.014 0.986 0.000
T38.0 Glucocorticoids and synthetic analogues
0.014 0.986 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.014 0.986 0.000
T46.7 Peripheral vasodilators
0.014 0.986 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.014 0.986 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.014 0.986 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.014 0.986 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.986 0.013
I05.1 Rheumatic mitral insufficiency
0.000 0.986 0.013
T50.4 Drugs affecting uric acid metabolism
0.013 0.986 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.013 0.987 0.000
T50.7 Analeptics and opioid receptor antagonists
0.013 0.987 0.000
T50.5 Appetite depressants
0.013 0.987 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.013 0.987 0.000
T50.1 Loop [high-ceiling] diuretics
0.013 0.987 0.000
T50.0 Mineralocorticoids and their antagonists
0.013 0.987 0.000
F33 Recurrent depressive disorder
0.000 0.987 0.013
I12.9 Hypertensive renal disease without renal failure
0.000 0.987 0.013
I05.2 Mitral stenosis with insufficiency
0.000 0.987 0.013
T36.0 Penicillins
0.013 0.987 0.000
I05.0 Mitral stenosis
0.000 0.987 0.013
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.013 0.987 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.013 0.987 0.000
T47.7 Emetics
0.013 0.987 0.000
T47.6 Antidiarrhoeal drugs
0.013 0.987 0.000
T47.5 Digestants
0.013 0.987 0.000
T47.4 Other laxatives
0.013 0.987 0.000
T47.3 Saline and osmotic laxatives
0.013 0.987 0.000
T47.2 Stimulant laxatives
0.013 0.987 0.000
T47.0 Histamine H(2)-receptor antagonists
0.013 0.987 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.013 0.987 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.012 0.987 0.000
I27.1 Kyphoscoliotic heart disease
0.000 0.988 0.012
I82.3 Embolism and thrombosis of renal vein
0.000 0.988 0.012
T45.2 Vitamins, not elsewhere classified
0.012 0.988 0.000
R61.9 Hyperhidrosis, unspecified
0.000 0.988 0.012
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.988 0.012
T45.1 Antineoplastic and immunosuppressive drugs
0.012 0.988 0.000
T50.8 Diagnostic agents
0.012 0.988 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.988 0.012
T36.9 Systemic antibiotic, unspecified
0.012 0.988 0.000
T36.8 Other systemic antibiotics
0.012 0.988 0.000
T36.7 Antifungal antibiotics, systemically used
0.012 0.988 0.000
T36.6 Rifamycins
0.012 0.988 0.000
T36.5 Aminoglycosides
0.012 0.988 0.000
T36.4 Tetracyclines
0.012 0.988 0.000
T36.3 Macrolides
0.012 0.988 0.000
T36.2 Chloramphenicol group
0.012 0.988 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.012 0.988 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.011 0.988 0.000
T45.8 Other primarily systemic and haematological agents
0.011 0.988 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.011 0.988 0.000
T45.6 Fibrinolysis-affecting drugs
0.011 0.988 0.000
T45.4 Iron and its compounds
0.011 0.988 0.000
T45.3 Enzymes, not elsewhere classified
0.011 0.988 0.000
T45.0 Antiallergic and antiemetic drugs
0.012 0.988 0.000
T45.5 Anticoagulants
0.011 0.989 0.000
I82.1 Thrombophlebitis migrans
0.000 0.989 0.011
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.011 0.989 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.001 0.989 0.011
M43.6 Torticollis
0.000 0.989 0.011
M43.0 Spondylolysis
0.000 0.989 0.011
T41.5 Therapeutic gases
0.011 0.989 0.000
T41.4 Anaesthetic, unspecified
0.011 0.989 0.000
T41.3 Local anaesthetics
0.011 0.989 0.000
T41.2 Other and unspecified general anaesthetics
0.011 0.989 0.000
T41.1 Intravenous anaesthetics
0.011 0.989 0.000
T41.0 Inhaled anaesthetics
0.011 0.989 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.011 0.989 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.011 0.989 0.000
T48.5 Anti-common-cold drugs
0.011 0.989 0.000
T48.4 Expectorants
0.011 0.989 0.000
T48.3 Antitussives
0.011 0.989 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.011 0.989 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.011 0.989 0.000
T48.0 Oxytocic drugs
0.011 0.989 0.000
T49.9 Topical agent, unspecified
0.011 0.989 0.000
T49.8 Other topical agents
0.011 0.989 0.000
T49.7 Dental drugs, topically applied
0.011 0.989 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.011 0.989 0.000
T49.5 Ophthalmological drugs and preparations
0.011 0.989 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.011 0.989 0.000
T49.3 Emollients, demulcents and protectants
0.011 0.989 0.000
T49.2 Local astringents and local detergents
0.011 0.989 0.000
T49.1 Antipruritics
0.011 0.989 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.011 0.989 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.989 0.011
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.011 0.989 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.011 0.989 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.011 0.989 0.000
T37.5 Antiviral drugs
0.011 0.989 0.000
T37.4 Anthelminthics
0.011 0.989 0.000
T37.3 Other antiprotozoal drugs
0.011 0.989 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.011 0.989 0.000
T37.1 Antimycobacterial drugs
0.011 0.989 0.000
T37.0 Sulphonamides
0.011 0.989 0.000
M43.9 Deforming dorsopathy, unspecified
0.000 0.989 0.011
M43.8 Other specified deforming dorsopathies
0.000 0.989 0.011
M43.5 Other recurrent vertebral subluxation
0.000 0.989 0.011
M43.4 Other recurrent atlantoaxial subluxation
0.000 0.989 0.011
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.000 0.989 0.011
I05.9 Mitral valve disease, unspecified
0.000 0.989 0.011
T37.8 Other specified systemic anti-infectives and antiparasitics
0.010 0.989 0.000
I87.9 Disorder of vein, unspecified
0.000 0.989 0.010
I87.0 Postphlebitic syndrome
0.000 0.989 0.010
I27.9 Pulmonary heart disease, unspecified
0.000 0.990 0.010
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.990 0.010
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.010 0.990 0.000
I78.1 Naevus, nonneoplastic
0.000 0.990 0.010
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.990 0.010
M43.17 Spondylolisthesis (Lumbosacral region)
0.000 0.990 0.010
I82.0 Budd-Chiari syndrome
0.000 0.990 0.010
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.010 0.990 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.990 0.010
M43.09 Spondylolysis (Site unspecified)
0.000 0.990 0.010
F33.8 Other recurrent depressive disorders
0.000 0.990 0.010
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.990 0.010
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.000 0.990 0.010
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.990 0.009
T43.2 Other and unspecified antidepressants
0.010 0.990 0.000
C53.9 Cervix uteri, unspecified
0.009 0.991 0.000
K75.4 Autoimmune hepatitis
0.000 0.991 0.009
M43.2 Other fusion of spine
0.000 0.991 0.009
I77.6 Arteritis, unspecified
0.000 0.991 0.009
I82.8 Embolism and thrombosis of other specified veins
0.000 0.991 0.009
M43.62 Torticollis-Cervical
0.000 0.991 0.009
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.991 0.009
I85.0 Oesophageal varices with bleeding
0.002 0.991 0.006
T40.1 Heroin
0.008 0.991 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.992 0.008
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.008 0.992 0.000
T40.8 Lysergide [LSD]
0.008 0.992 0.000
T40.7 Cannabis (derivatives)
0.008 0.992 0.000
T40.3 Methadone
0.008 0.992 0.000
T40.0 Opium
0.008 0.992 0.000
M43.69 Torticollis-Site unspe
0.000 0.992 0.008
M43.68 Torticollis-Sacral/sacrococ
0.000 0.992 0.008
M43.67 Torticollis-Lumbosacral
0.000 0.992 0.008
M43.66 Torticollis-Lumbar
0.000 0.992 0.008
M43.65 Torticollis-Thoracolumbar
0.000 0.992 0.008
M43.64 Torticollis-Thoracic
0.000 0.992 0.008
M43.63 Torticollis-Cervicothoracic
0.000 0.992 0.008
M43.61 Torticollis-Occipit-atl-axl
0.000 0.992 0.008
M43.60 Torticollis-Mult site
0.000 0.992 0.008
T40.4 Other synthetic narcotics
0.008 0.992 0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)
0.000 0.992 0.008
M43.05 Spondylolysis (Thoracolumbar region)
0.000 0.992 0.008
M43.04 Spondylolysis (Thoracic region)
0.000 0.992 0.008
M43.03 Spondylolysis (Cervicothoracic region)
0.000 0.992 0.008
M43.01 Spondylolysis (Occipito-atlanto-axial region)
0.000 0.992 0.008
M43.00 Spondylolysis (Multiple sites in spine)
0.000 0.992 0.008
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.992 0.008
T39.4 Antirheumatics, not elsewhere classified
0.008 0.992 0.000
T39.2 Pyrazolone derivatives
0.008 0.992 0.000
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)
0.000 0.992 0.008
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)
0.000 0.992 0.008
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)
0.000 0.992 0.008
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)
0.000 0.992 0.008
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)
0.000 0.992 0.008
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)
0.000 0.992 0.008
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)
0.000 0.992 0.008
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)
0.000 0.992 0.008
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)
0.000 0.992 0.008
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)
0.000 0.992 0.008
M43.49 Other recurrent atlantoaxial subluxation-Site unspe
0.000 0.992 0.008
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ
0.000 0.992 0.008
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral
0.000 0.992 0.008
M43.46 Other recurrent atlantoaxial subluxation-Lumbar
0.000 0.992 0.008
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar
0.000 0.992 0.008
M43.44 Other recurrent atlantoaxial subluxation-Thoracic
0.000 0.992 0.008
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic
0.000 0.992 0.008
M43.42 Other recurrent atlantoaxial subluxation-Cervical
0.000 0.992 0.008
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl
0.000 0.992 0.008
M43.40 Other recurrent atlantoaxial subluxation-Mult site
0.000 0.992 0.008
M43.59 Other recurrent vertebral subluxation (Site unspecified)
0.000 0.992 0.008
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)
0.000 0.992 0.008
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)
0.000 0.992 0.008
M43.56 Other recurrent vertebral subluxation (Lumbar region)
0.000 0.992 0.008
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)
0.000 0.992 0.008
M43.54 Other recurrent vertebral subluxation (Thoracic region)
0.000 0.992 0.008
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)
0.000 0.992 0.008
M43.52 Other recurrent vertebral subluxation (Cervical region)
0.000 0.992 0.008
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl
0.000 0.992 0.008
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)
0.000 0.992 0.008
M43.89 Other specified deforming dorsopathies (Site unspecified)
0.000 0.992 0.008
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)
0.000 0.992 0.008
M43.87 Other specified deforming dorsopathies (Lumbosacral region)
0.000 0.992 0.008
M43.86 Other specified deforming dorsopathies (Lumbar region)
0.000 0.992 0.008
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)
0.000 0.992 0.008
M43.84 Other specified deforming dorsopathies (Thoracic region)
0.000 0.992 0.008
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)
0.000 0.992 0.008
M43.82 Other specified deforming dorsopathies (Cervical region)
0.000 0.992 0.008
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)
0.000 0.992 0.008
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)
0.000 0.992 0.008
M43.99 Deforming dorsopathy, unspecified (Site unspecified)
0.000 0.992 0.008
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.000 0.992 0.008
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)
0.000 0.992 0.008
M43.96 Deforming dorsopathy, unspecified (Lumbar region)
0.000 0.992 0.008
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)
0.000 0.992 0.008
M43.94 Deforming dorsopathy, unspecified (Thoracic region)
0.000 0.992 0.008
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)
0.000 0.992 0.008
M43.92 Deforming dorsopathy, unspecified (Cervical region)
0.000 0.992 0.008
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)
0.000 0.992 0.008
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)
0.000 0.992 0.008
M43.06 Spondylolysis (Lumbar region)
0.000 0.992 0.008
T40.5 Cocaine
0.008 0.992 0.000
M40-M43 Deforming dorsopathies
0.000 0.992 0.008
M43.02 Spondylolysis (Cervical region)
0.000 0.992 0.008
M43.07 Spondylolysis (Lumbosacral region)
0.000 0.992 0.007
T42.5 Mixed antiepileptics, not elsewhere classified
0.007 0.992 0.000
T42.3 Barbiturates
0.007 0.992 0.000
T42.2 Succinimides and oxazolidinediones
0.007 0.992 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.007 0.993 0.000
K75 Other inflammatory liver diseases
0.000 0.993 0.007
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.993 0.007
F30-F39 Mood [affective] disorders
0.000 0.993 0.007
I27.2 Other secondary pulmonary hypertension
0.000 0.993 0.007
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.007 0.993 0.000
F30 Manic episode
0.000 0.993 0.007
T42.4 Benzodiazepines
0.007 0.993 0.000
T42.0 Hydantoin derivatives
0.007 0.993 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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