TreeWAS – Variant ID: rs12873154

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.2 Old myocardial infarction	0.995	0.005	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.950	0.050	0.000
I20-I25 Ischaemic heart diseases	0.904	0.096	0.000
I21 Acute myocardial infarction	0.885	0.115	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.849	0.151	0.000
I25.5 Ischaemic cardiomyopathy	0.848	0.152	0.000
I24 Other acute ischaemic heart diseases	0.847	0.153	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.811	0.189	0.000
I25.4 Coronary artery aneurysm	0.807	0.193	0.000
I25.6 Silent myocardial ischaemia	0.800	0.200	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.752	0.248	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.739	0.261	0.000
I25.3 Aneurysm of heart	0.720	0.280	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.714	0.286	0.000
I24.8 Other forms of acute ischaemic heart disease	0.704	0.296	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.665	0.335	0.000
I21.4 Acute subendocardial myocardial infarction	0.661	0.339	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.635	0.365	0.000
I23 Certain current complications following acute myocardial infarction	0.622	0.378	0.000
I21.9 Acute myocardial infarction, unspecified	0.622	0.378	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.612	0.388	0.000
I24.1 Dressler's syndrome	0.599	0.400	0.000
S00-S09 Injuries to the head	0.537	0.463	0.000
S09 Other and unspecified injuries of head	0.524	0.476	0.000
S09.9 Unspecified injury of head	0.519	0.481	0.000
S06 Intracranial injury	0.518	0.482	0.000
S01 Open wound of head	0.514	0.486	0.000
S01.9 Open wound of head, part unspecified	0.502	0.498	0.000
S00 Superficial injury of head	0.499	0.501	0.000
S06.0 Concussion	0.492	0.508	0.000
S00.9 Superficial injury of head, part unspecified	0.488	0.512	0.000
S06.00 Concussion (without open intracranial wound)	0.474	0.526	0.000
S06.8 Other intracranial injuries	0.469	0.531	0.000
S00.8 Superficial injury of other parts of head	0.460	0.540	0.000
I22 Subsequent myocardial infarction	0.449	0.551	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.446	0.554	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.446	0.554	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.446	0.554	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.446	0.554	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.446	0.554	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.446	0.554	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.446	0.554	0.000
S05 Injury of eye and orbit	0.436	0.564	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.435	0.564	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.435	0.565	0.000
S02 Fracture of skull and facial bones	0.428	0.572	0.000
S06.3 Focal brain injury	0.427	0.573	0.000
S01.5 Open wound of lip and oral cavity	0.420	0.580	0.000
I23.8 Other current complications following acute myocardial infarction	0.420	0.580	0.000
S01.1 Open wound of eyelid and periocular area	0.404	0.596	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.398	0.602	0.000
S06.5 Traumatic subdural haemorrhage	0.390	0.610	0.000
S01.8 Open wound of other parts of head	0.385	0.615	0.000
S08 Traumatic amputation of part of head	0.385	0.615	0.000
S07 Crushing injury of head	0.385	0.615	0.000
S04 Injury of cranial nerves	0.385	0.615	0.000
S09.7 Multiple injuries of head	0.376	0.624	0.000
S09.2 Traumatic rupture of ear drum	0.376	0.624	0.000
S09.1 Injury of muscle and tendon of head	0.376	0.624	0.000
S06.7 Intracranial injury with prolonged coma	0.371	0.629	0.000
S06.1 Traumatic cerebral oedema	0.371	0.629	0.000
S00.7 Multiple superficial injuries of head	0.371	0.629	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.367	0.633	0.000
S02.6 Fracture of mandible	0.363	0.637	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.362	0.638	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.362	0.638	0.000
S00.4 Superficial injury of ear	0.362	0.638	0.000
S03.0 Dislocation of jaw	0.362	0.638	0.000
S02.0 Fracture of vault of skull	0.359	0.641	0.000
S01.7 Multiple open wounds of head	0.359	0.641	0.000
S01.2 Open wound of nose	0.357	0.643	0.000
S06.01 Concussion (with open intracranial wound)	0.353	0.647	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.350	0.650	0.000
S00.5 Superficial injury of lip and oral cavity	0.350	0.650	0.000
S05.1 Contusion of eyeball and orbital tissues	0.347	0.653	0.000
S06.9 Intracranial injury, unspecified	0.343	0.657	0.000
S06.4 Epidural haemorrhage	0.340	0.660	0.000
I22.8 Subsequent myocardial infarction of other sites	0.339	0.660	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.337	0.663	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.336	0.663	0.000
S01.4 Open wound of cheek and temporomandibular area	0.327	0.673	0.000
S02.1 Fracture of base of skull	0.326	0.674	0.000
S09.8 Other specified injuries of head	0.324	0.676	0.000
S06.2 Diffuse brain injury	0.322	0.677	0.000
S02.8 Fractures of other skull and facial bones	0.320	0.680	0.000
I20 Angina pectoris	0.319	0.681	0.000
S01.3 Open wound of ear	0.318	0.681	0.000
S02.60 Fracture of mandible (closed)	0.316	0.684	0.000
S03.2 Dislocation of tooth	0.314	0.686	0.000
S05.7 Avulsion of eye	0.313	0.687	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.313	0.687	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.313	0.687	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.313	0.687	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.313	0.687	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.312	0.688	0.000
S03.4 Sprain and strain of jaw	0.312	0.688	0.000
S03.3 Dislocation of other and unspecified parts of head	0.312	0.688	0.000
S03.1 Dislocation of septal cartilage of nose	0.312	0.688	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.312	0.688	0.000
S02.00 Fracture of vault of skull (closed)	0.310	0.690	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.306	0.693	0.000
S02.5 Fracture of tooth	0.306	0.694	0.000
S02.4 Fracture of malar and maxillary bones	0.306	0.694	0.000
S05.8 Other injuries of eye and orbit	0.304	0.696	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.300	0.700	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.299	0.701	0.000
S01.0 Open wound of scalp	0.291	0.709	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.284	0.716	0.000
S02.7 Multiple fractures involving skull and facial bones	0.280	0.720	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.280	0.720	0.000
S04.9 Injury of unspecified cranial nerve	0.276	0.724	0.000
S04.8 Injury of other cranial nerves	0.276	0.724	0.000
S04.7 Injury of accessory nerve	0.276	0.724	0.000
S04.6 Injury of acoustic nerve	0.276	0.724	0.000
S04.5 Injury of facial nerve	0.276	0.724	0.000
S04.4 Injury of abducent nerve	0.276	0.724	0.000
S04.3 Injury of trigeminal nerve	0.276	0.724	0.000
S04.2 Injury of trochlear nerve	0.276	0.724	0.000
S04.1 Injury of oculomotor nerve	0.276	0.724	0.000
S04.0 Injury of optic nerve and pathways	0.276	0.724	0.000
S07.9 Crushing injury of head, part unspecified	0.276	0.724	0.000
S07.8 Crushing injury of other parts of head	0.276	0.724	0.000
S07.1 Crushing injury of skull	0.276	0.724	0.000
S07.0 Crushing injury of face	0.276	0.724	0.000
S08.9 Traumatic amputation of unspecified part of head	0.276	0.724	0.000
S08.8 Traumatic amputation of other parts of head	0.276	0.724	0.000
S08.1 Traumatic amputation of ear	0.276	0.724	0.000
S08.0 Avulsion of scalp	0.276	0.724	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.273	0.727	0.000
S05.9 Injury of eye and orbit, part unspecified	0.272	0.728	0.000
S02.3 Fracture of orbital floor	0.268	0.732	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.266	0.734	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.266	0.734	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.266	0.734	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.266	0.734	0.000
S02.61 Fracture of mandible (open)	0.260	0.740	0.000
S02.01 Fracture of vault of skull (open)	0.258	0.742	0.000
S02.10 Fracture of base of skull (closed)	0.253	0.747	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.246	0.754	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.244	0.756	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.243	0.757	0.000
I20.8 Other forms of angina pectoris	0.241	0.759	0.000
S00.1 Contusion of eyelid and periocular area	0.237	0.763	0.000
S02.11 Fracture of base of skull (open)	0.234	0.766	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.231	0.769	0.000
S02.81 Fractures of other skull and facial bones (open)	0.230	0.770	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.228	0.772	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.224	0.776	0.000
S02.51 Fracture of tooth (open)	0.219	0.781	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.219	0.781	0.000
S02.2 Fracture of nasal bones	0.218	0.781	0.000
S02.50 Fracture of tooth (closed)	0.218	0.782	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.218	0.782	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.218	0.782	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.215	0.785	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.213	0.787	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.204	0.796	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.201	0.799	0.000
S00.0 Superficial injury of scalp	0.197	0.802	0.000
I20.1 Angina pectoris with documented spasm	0.192	0.807	0.000
S02.31 Fracture of orbital floor (open)	0.192	0.808	0.000
S00.3 Superficial injury of nose	0.191	0.808	0.001
S06.20 Diffuse brain injury (without open intracranial wound)	0.182	0.817	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.174	0.826	0.000
S02.21 Fracture of nasal bones (open)	0.157	0.843	0.000
I20.9 Angina pectoris, unspecified	0.157	0.843	0.000
S02.30 Fracture of orbital floor (closed)	0.153	0.847	0.000
I20.0 Unstable angina	0.125	0.875	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.116	0.883	0.001
D13.1 Stomach	0.000	0.895	0.105
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.098	0.902	0.000
S90-S99 Injuries to the ankle and foot	0.097	0.903	0.000
S92 Fracture of foot, except ankle	0.095	0.905	0.000
S92.2 Fracture of other tarsal bone(s)	0.090	0.910	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.088	0.912	0.000
S40-S49 Injuries to the shoulder and upper arm	0.088	0.912	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.087	0.913	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.084	0.916	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.083	0.917	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.083	0.917	0.000
S40 Superficial injury of shoulder and upper arm	0.082	0.918	0.000
S92.5 Fracture of other toe	0.082	0.918	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.080	0.920	0.000
S92.4 Fracture of great toe	0.080	0.920	0.000
T91 Sequelae of injuries of neck and trunk	0.078	0.922	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.078	0.922	0.000
S92.7 Multiple fractures of foot	0.078	0.922	0.000
S93.1 Dislocation of toe(s)	0.075	0.925	0.000
S40.0 Contusion of shoulder and upper arm	0.075	0.925	0.000
T13 Other injuries of lower limb, level unspecified	0.074	0.925	0.000
T40.4 Other synthetic narcotics	0.074	0.926	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.927	0.073
S90 Superficial injury of ankle and foot	0.073	0.927	0.000
S92.51 Fracture of other toe (open)	0.072	0.928	0.000
T33-T35 Frostbite	0.070	0.930	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.070	0.930	0.000
T00-T07 Injuries involving multiple body regions	0.070	0.930	0.000
S99 Other and unspecified injuries of ankle and foot	0.070	0.930	0.000
T09 Other injuries of spine and trunk, level unspecified	0.070	0.930	0.000
S98 Traumatic amputation of ankle and foot	0.070	0.930	0.000
S97 Crushing injury of ankle and foot	0.070	0.930	0.000
S95 Injury of blood vessels at ankle and foot level	0.070	0.930	0.000
S94 Injury of nerves at ankle and foot level	0.070	0.930	0.000
S50-S59 Injuries to the elbow and forearm	0.070	0.930	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.069	0.931	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.069	0.931	0.000
T14 Injury of unspecified body region	0.069	0.931	0.000
T91.1 Sequelae of fracture of spine	0.068	0.931	0.000
S92.9 Fracture of foot, unspecified	0.068	0.931	0.000
T40.6 Other and unspecified narcotics	0.068	0.932	0.000
S02.20 Fracture of nasal bones (closed)	0.068	0.932	0.000
S92.40 Fracture of great toe (closed)	0.068	0.932	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.067	0.933	0.000
S92.1 Fracture of talus	0.066	0.934	0.000
T40.2 Other opioids	0.066	0.934	0.000
S92.70 Multiple fractures of foot (closed)	0.066	0.934	0.000
D13.0 Oesophagus	0.000	0.934	0.066
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.065	0.934	0.000
T11 Other injuries of upper limb, level unspecified	0.065	0.935	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.065	0.935	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.065	0.935	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.065	0.935	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.065	0.935	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.065	0.935	0.000
S42 Fracture of shoulder and upper arm	0.064	0.935	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.064	0.936	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.064	0.936	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.063	0.937	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.063	0.937	0.000
T12 Fracture of lower limb, level unspecified	0.063	0.937	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.063	0.937	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.063	0.937	0.000
T10 Fracture of upper limb, level unspecified	0.063	0.937	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.063	0.937	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.063	0.937	0.000
T08 Fracture of spine, level unspecified	0.063	0.937	0.000
S48 Traumatic amputation of shoulder and upper arm	0.063	0.937	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.063	0.937	0.000
S44 Injury of nerves at shoulder and upper arm level	0.063	0.937	0.000
S47 Crushing injury of shoulder and upper arm	0.063	0.937	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.063	0.937	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.063	0.937	0.000
S70-S79 Injuries to the hip and thigh	0.062	0.938	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.062	0.938	0.000
T79-T79 Certain early complications of trauma	0.062	0.938	0.000
S52 Fracture of forearm	0.062	0.938	0.000
T98 Sequelae of other and unspecified effects of external causes	0.061	0.938	0.000
T91.3 Sequelae of injury of spinal cord	0.061	0.939	0.000
S92.50 Fracture of other toe (closed)	0.061	0.939	0.000
S46.3 Injury of muscle and tendon of triceps	0.061	0.939	0.000
T93 Sequelae of injuries of lower limb	0.061	0.939	0.000
S92.3 Fracture of metatarsal bone	0.061	0.939	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.061	0.939	0.000
T66-T78 Other and unspecified effects of external causes	0.061	0.939	0.000
S52.0 Fracture of upper end of ulna	0.061	0.939	0.000
S92.41 Fracture of great toe (open)	0.060	0.939	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.060	0.940	0.000
S93.4 Sprain and strain of ankle	0.060	0.940	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.060	0.940	0.000
S93.5 Sprain and strain of toe(s)	0.060	0.940	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.060	0.940	0.000
S91 Open wound of ankle and foot	0.060	0.940	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.060	0.940	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.060	0.940	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.060	0.940	0.000
S52.00 Fracture of upper end of ulna (closed)	0.060	0.940	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.059	0.940	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.059	0.940	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.059	0.940	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.059	0.940	0.000
T90 Sequelae of injuries of head	0.059	0.941	0.000
T82.1 Mechanical complication of cardiac electronic device	0.059	0.941	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.059	0.941	0.000
T36 Poisoning by systemic antibiotics	0.059	0.941	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.059	0.941	0.000
T95 Sequelae of burns, corrosions and frostbite	0.059	0.941	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.058	0.941	0.000
S90.1 Contusion of toe(s) without damage to nail	0.058	0.942	0.000
D13.4 Liver	0.000	0.942	0.058
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.058	0.942	0.000
T40.8 Lysergide [LSD]	0.058	0.942	0.000
T40.7 Cannabis (derivatives)	0.058	0.942	0.000
T40.5 Cocaine	0.058	0.942	0.000
T40.3 Methadone	0.058	0.942	0.000
T40.1 Heroin	0.058	0.942	0.000
T40.0 Opium	0.058	0.942	0.000
S10-S19 Injuries to the neck	0.058	0.942	0.000
S42.3 Fracture of shaft of humerus	0.058	0.942	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.057	0.943	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.057	0.943	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.057	0.943	0.000
S42.1 Fracture of scapula	0.057	0.943	0.000
T09.9 Unspecified injury of trunk, level unspecified	0.057	0.943	0.000
D13.2 Duodenum	0.000	0.943	0.057
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.056	0.944	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.056	0.944	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.056	0.944	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.056	0.944	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.056	0.944	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.056	0.944	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.056	0.944	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.056	0.944	0.000
S92.71 Multiple fractures of foot (open)	0.056	0.944	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.055	0.944	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.055	0.945	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.055	0.945	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.054	0.946	0.000
S59 Other and unspecified injuries of forearm	0.054	0.946	0.000
T14.9 Injury, unspecified	0.054	0.946	0.000
S93.0 Dislocation of ankle joint	0.054	0.946	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.054	0.946	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.054	0.946	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.054	0.946	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.054	0.946	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.054	0.946	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.054	0.946	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.054	0.946	0.000
T13.1 Open wound of lower limb, level unspecified	0.054	0.946	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.054	0.946	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.053	0.946	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.053	0.946	0.000
T93.1 Sequelae of fracture of femur	0.053	0.947	0.000
S90.0 Contusion of ankle	0.053	0.947	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.053	0.947	0.000
S42.30 Fracture of shaft of humerus (closed)	0.053	0.947	0.000
D13.9 Ill-defined sites within the digestive system	0.000	0.947	0.053
D13.7 Endocrine pancreas	0.000	0.947	0.053
S92.0 Fracture of calcaneus	0.052	0.948	0.000
S54 Injury of nerves at forearm level	0.052	0.948	0.000
D13.6 Pancreas	0.000	0.948	0.052
S90.7 Multiple superficial injuries of ankle and foot	0.052	0.948	0.000
S90.3 Contusion of other and unspecified parts of foot	0.052	0.948	0.000
S90.2 Contusion of toe(s) with damage to nail	0.052	0.948	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.052	0.948	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.052	0.948	0.000
T02 Fractures involving multiple body regions	0.052	0.948	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.052	0.948	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.052	0.948	0.000
T94.1 Sequelae of injuries, not specified by body region	0.052	0.948	0.000
S42.10 Fracture of scapula (closed)	0.052	0.948	0.000
S41 Open wound of shoulder and upper arm	0.051	0.949	0.000
D13.5 Extrahepatic bile ducts	0.000	0.949	0.051
S99.9 Unspecified injury of ankle and foot	0.051	0.949	0.000
S52.6 Fracture of lower end of both ulna and radius	0.051	0.949	0.000
T00 Superficial injuries involving multiple body regions	0.051	0.949	0.000
T28 Burn and corrosion of other internal organs	0.051	0.949	0.000
T27 Burn and corrosion of respiratory tract	0.051	0.949	0.000
T26 Burn and corrosion confined to eye and adnexa	0.051	0.949	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.051	0.949	0.000
T34 Frostbite with tissue necrosis	0.051	0.949	0.000
T33 Superficial frostbite	0.051	0.949	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.051	0.949	0.000
T05 Traumatic amputations involving multiple body regions	0.051	0.949	0.000
T04 Crushing injuries involving multiple body regions	0.051	0.949	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.051	0.949	0.000
T07 Unspecified multiple injuries	0.051	0.949	0.000
S99.8 Other specified injuries of ankle and foot	0.051	0.949	0.000
S99.7 Multiple injuries of ankle and foot	0.051	0.949	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.051	0.949	0.000
T14.1 Open wound of unspecified body region	0.050	0.950	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.050	0.950	0.000
T09.6 Traumatic amputation of trunk, level unspecified	0.050	0.950	0.000
T09.5 Injury of unspecified muscle and tendon of trunk	0.050	0.950	0.000
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.050	0.950	0.000
T09.3 Injury of spinal cord, level unspecified	0.050	0.950	0.000
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.050	0.950	0.000
T09.1 Open wound of trunk, level unspecified	0.050	0.950	0.000
T09.0 Superficial injury of trunk, level unspecified	0.050	0.950	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.050	0.950	0.000
S94.8 Injury of other nerves at ankle and foot level	0.050	0.950	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.050	0.950	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.050	0.950	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.050	0.950	0.000
S94.1 Injury of medial plantar nerve	0.050	0.950	0.000
S94.0 Injury of lateral plantar nerve	0.050	0.950	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.050	0.950	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.050	0.950	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.050	0.950	0.000
S95.2 Injury of dorsal vein of foot	0.050	0.950	0.000
S95.1 Injury of plantar artery of foot	0.050	0.950	0.000
S95.0 Injury of dorsal artery of foot	0.050	0.950	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.050	0.950	0.000
S97.1 Crushing injury of toe(s)	0.050	0.950	0.000
S97.0 Crushing injury of ankle	0.050	0.950	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.050	0.950	0.000
S98.3 Traumatic amputation of other parts of foot	0.050	0.950	0.000
S98.2 Traumatic amputation of two or more toes	0.050	0.950	0.000
S98.1 Traumatic amputation of one toe	0.050	0.950	0.000
S98.0 Traumatic amputation of foot at ankle level	0.050	0.950	0.000
S58 Traumatic amputation of forearm	0.050	0.950	0.000
S57 Crushing injury of forearm	0.050	0.950	0.000
S55 Injury of blood vessels at forearm level	0.050	0.950	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.050	0.950	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.050	0.950	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.050	0.950	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.050	0.950	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.050	0.950	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.050	0.950	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.050	0.950	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.050	0.950	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.050	0.950	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.050	0.950	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.050	0.950	0.000
T46.7 Peripheral vasodilators	0.050	0.950	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.050	0.950	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.050	0.950	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.050	0.950	0.000
T68 Hypothermia	0.050	0.950	0.000
T14.0 Superficial injury of unspecified body region	0.049	0.950	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.049	0.950	0.000
T14.2 Fracture of unspecified body region	0.049	0.950	0.000
T14.8 Other injuries of unspecified body region	0.049	0.950	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.049	0.950	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.049	0.950	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.049	0.950	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.049	0.950	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.049	0.950	0.000
S92.91 Fracture of foot, unspecified (open)	0.049	0.951	0.000
S92.90 Fracture of foot, unspecified (closed)	0.049	0.951	0.000
T01 Open wounds involving multiple body regions	0.049	0.951	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.049	0.951	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.049	0.951	0.000
S80-S89 Injuries to the knee and lower leg	0.049	0.951	0.000
D13.3 Other and unspecified parts of small intestine	0.000	0.951	0.048
T90.4 Sequelae of injury of eye and orbit	0.048	0.952	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.048	0.952	0.000
S92.11 Fracture of talus (open)	0.048	0.952	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.047	0.952	0.000
T46.1 Calcium-channel blockers	0.047	0.952	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.048	0.952	0.000
S52.01 Fracture of upper end of ulna (open)	0.047	0.953	0.000
T50.8 Diagnostic agents	0.047	0.953	0.000
T50.7 Analeptics and opioid receptor antagonists	0.047	0.953	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.047	0.953	0.000
T50.5 Appetite depressants	0.047	0.953	0.000
T50.4 Drugs affecting uric acid metabolism	0.047	0.953	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.047	0.953	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.047	0.953	0.000
T50.1 Loop [high-ceiling] diuretics	0.047	0.953	0.000
T50.0 Mineralocorticoids and their antagonists	0.047	0.953	0.000
T75 Effects of other external causes	0.047	0.953	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.047	0.953	0.000
T11.9 Unspecified injury of upper limb, level unspecified	0.047	0.953	0.000
T11.8 Other specified injuries of upper limb, level unspecified	0.047	0.953	0.000
T11.6 Traumatic amputation of upper limb, level unspecified	0.047	0.953	0.000
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.047	0.953	0.000
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.047	0.953	0.000
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.047	0.953	0.000
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.047	0.953	0.000
T11.1 Open wound of upper limb, level unspecified	0.047	0.953	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.047	0.953	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.047	0.953	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.047	0.953	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.047	0.953	0.000
R87.6 Abnormal cytological findings	0.000	0.953	0.047
S42.8 Fracture of other parts of shoulder and upper arm	0.046	0.953	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.046	0.953	0.000
S72 Fracture of femur	0.046	0.954	0.000
S50 Superficial injury of forearm	0.046	0.954	0.000
S13.4 Sprain and strain of cervical spine	0.046	0.954	0.000
S52.7 Multiple fractures of forearm	0.046	0.954	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.046	0.954	0.000
S79 Other and unspecified injuries of hip and thigh	0.046	0.954	0.000
S71 Open wound of hip and thigh	0.046	0.954	0.000
T90.1 Sequelae of open wound of head	0.046	0.954	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.045	0.954	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.045	0.954	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.045	0.954	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.045	0.954	0.000
S44.4 Injury of musculocutaneous nerve	0.045	0.954	0.000
S44.3 Injury of axillary nerve	0.045	0.954	0.000
S44.2 Injury of radial nerve at upper arm level	0.045	0.954	0.000
S44.1 Injury of median nerve at upper arm level	0.045	0.954	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.045	0.954	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.045	0.954	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.045	0.954	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.045	0.954	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.045	0.954	0.000
S45.2 Injury of axillary or brachial vein	0.045	0.954	0.000
S45.1 Injury of brachial artery	0.045	0.954	0.000
S45.0 Injury of axillary artery	0.045	0.954	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.045	0.954	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.045	0.954	0.000
S48.0 Traumatic amputation at shoulder joint	0.045	0.954	0.000
T86 Failure and rejection of transplanted organs and tissues	0.046	0.954	0.000
S92.10 Fracture of talus (closed)	0.045	0.955	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.045	0.955	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.045	0.955	0.000
T90.9 Sequelae of unspecified injury of head	0.045	0.955	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.045	0.955	0.000
S78 Traumatic amputation of hip and thigh	0.045	0.955	0.000
S77 Crushing injury of hip and thigh	0.045	0.955	0.000
S75 Injury of blood vessels at hip and thigh level	0.045	0.955	0.000
S74 Injury of nerves at hip and thigh level	0.045	0.955	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.045	0.955	0.000
T39.4 Antirheumatics, not elsewhere classified	0.045	0.955	0.000
T39.2 Pyrazolone derivatives	0.045	0.955	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.045	0.955	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations