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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs928815
log Bayes Factor = 87.1834
Chromosome 6   position 31,531,215  (GRCh37) Explore rs928815 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.1 With ketoacidosis
0.000 0.001 0.999
E10.4 With neurological complications
0.000 0.002 0.998
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.003 0.997
I20.0 Unstable angina
0.000 0.003 0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
E05.9 Thyrotoxicosis, unspecified
0.000 0.006 0.994
E78.0 Pure hypercholesterolaemia
0.000 0.007 0.993
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.008 0.992
E70-E90 Metabolic disorders
0.000 0.008 0.992
E14.3 With ophthalmic complications
0.000 0.009 0.991
E16 Other disorders of pancreatic internal secretion
0.000 0.009 0.991
E14.9 Without complications
0.000 0.011 0.989
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.014 0.986
E16.2 Hypoglycaemia, unspecified
0.000 0.014 0.986
E11.3 With ophthalmic complications
0.000 0.017 0.983
E10.2 With renal complications
0.000 0.043 0.957
H36.0 Diabetic retinopathy
0.000 0.048 0.952
I22 Subsequent myocardial infarction
0.000 0.057 0.943
I21 Acute myocardial infarction
0.000 0.065 0.935
M06.9 Rheumatoid arthritis, unspecified
0.000 0.067 0.933
I25.5 Ischaemic cardiomyopathy
0.000 0.073 0.927
I21.9 Acute myocardial infarction, unspecified
0.000 0.074 0.926
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.074 0.926
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.088 0.912
I24 Other acute ischaemic heart diseases
0.000 0.094 0.906
E11.1 With ketoacidosis
0.000 0.095 0.905
I25.2 Old myocardial infarction
0.000 0.100 0.900
E10.0 With coma
0.000 0.105 0.895
E06 Thyroiditis
0.000 0.107 0.893
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.108 0.892
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.122 0.878
E10.5 With peripheral circulatory complications
0.000 0.127 0.873
E88 Other metabolic disorders
0.000 0.129 0.871
E13 Other specified diabetes mellitus
0.000 0.135 0.865
E10.8 With unspecified complications
0.000 0.136 0.864
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.136 0.864
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.139 0.861
E11.0 With coma
0.000 0.147 0.853
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.150 0.850
E40-E46 Malnutrition
0.000 0.159 0.841
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.161 0.839
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.163 0.837
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.164 0.836
E06.3 Autoimmune thyroiditis
0.000 0.166 0.834
I24.8 Other forms of acute ischaemic heart disease
0.000 0.168 0.832
E14.6 With other specified complications
0.000 0.169 0.831
E14.8 With unspecified complications
0.000 0.179 0.821
E14.4 With neurological complications
0.000 0.186 0.814
E78.1 Pure hyperglyceridaemia
0.000 0.196 0.804
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.206 0.794
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.208 0.792
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.219 0.781
E11.2 With renal complications
0.000 0.219 0.781
E78.2 Mixed hyperlipidaemia
0.000 0.229 0.771
E10.6 With other specified complications
0.000 0.229 0.771
E74 Other disorders of carbohydrate metabolism
0.000 0.232 0.768
E78.6 Lipoprotein deficiency
0.000 0.241 0.759
E13.9 Without complications
0.000 0.243 0.757
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.245 0.755
E14.1 With ketoacidosis
0.000 0.246 0.754
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.248 0.752
I25.4 Coronary artery aneurysm
0.000 0.258 0.742
E78.4 Other hyperlipidaemia
0.000 0.266 0.734
E89.0 Postprocedural hypothyroidism
0.000 0.270 0.730
E16.1 Other hypoglycaemia
0.000 0.270 0.730
E79 Disorders of purine and pyrimidine metabolism
0.000 0.272 0.728
E46 Unspecified protein-energy malnutrition
0.000 0.273 0.727
E14.5 With peripheral circulatory complications
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.287 0.713
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.287 0.713
E78.3 Hyperchylomicronaemia
0.000 0.289 0.711
E89.3 Postprocedural hypopituitarism
0.000 0.289 0.711
E77 Disorders of glycoprotein metabolism
0.000 0.289 0.711
E76 Disorders of glycosaminoglycan metabolism
0.000 0.289 0.711
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.289 0.711
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.289 0.711
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.290 0.710
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.290 0.710
E16.4 Abnormal secretion of gastrin
0.000 0.290 0.710
E16.3 Increased secretion of glucagon
0.000 0.290 0.710
I23 Certain current complications following acute myocardial infarction
0.000 0.290 0.710
E14.2 Withrenal complications
0.000 0.292 0.707
E88.2 Lipomatosis, not elsewhere classified
0.000 0.294 0.706
M06 Other rheumatoid arthritis
0.000 0.295 0.705
E84 Cystic fibrosis
0.000 0.296 0.704
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.302 0.698
E73 Lactose intolerance
0.000 0.304 0.696
E70 Disorders of aromatic amino-acid metabolism
0.000 0.309 0.691
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.311 0.689
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.311 0.688
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.313 0.687
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.317 0.683
E06.5 Other chronic thyroiditis
0.000 0.324 0.676
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.329 0.671
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.330 0.670
I25.6 Silent myocardial ischaemia
0.000 0.335 0.665
E11.6 With other specified complications
0.000 0.337 0.663
E88.3 Tumour lysis syndrome
0.000 0.338 0.662
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.339 0.661
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.340 0.660
E88.9 Metabolic disorder, unspecified
0.000 0.346 0.654
E13.3 With ophthalmic complications
0.000 0.355 0.645
E72 Other disorders of amino-acid metabolism
0.000 0.359 0.641
E06.4 Drug-induced thyroiditis
0.000 0.360 0.640
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.360 0.640
E06.0 Acute thyroiditis
0.000 0.360 0.640
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.363 0.637
M06.3 Rheumatoid nodule
0.000 0.363 0.637
E89.4 Postprocedural ovarian failure
0.000 0.374 0.626
E78.8 Other disorders of lipoprotein metabolism
0.000 0.378 0.622
E88.8 Other specified metabolic disorders
0.000 0.379 0.621
E13.8 With unspecified complications
0.000 0.380 0.620
E13.7 With multiple complications
0.000 0.380 0.620
E13.6 With other specified complications
0.000 0.380 0.620
E13.5 With peripheral circulatory complications
0.000 0.380 0.620
E13.4 With neurological complications
0.000 0.380 0.620
E13.2 With renal complications
0.000 0.380 0.620
E13.1 With ketoacidosis
0.000 0.380 0.620
E13.0 With coma
0.000 0.380 0.620
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.392 0.608
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.392 0.608
G35 Multiple sclerosis
0.605 0.395 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.397 0.603
E45 Retarded development following protein-energy malnutrition
0.000 0.397 0.603
E43 Unspecified severe protein-energy malnutrition
0.000 0.397 0.603
E42 Marasmic kwashiorkor
0.000 0.397 0.603
E41 Nutritional marasmus
0.000 0.397 0.603
E40 Kwashiorkor
0.000 0.397 0.603
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.398 0.602
E89.5 Postprocedural testicular hypofunction
0.000 0.398 0.602
E89.1 Postprocedural hypoinsulinaemia
0.000 0.398 0.602
E14.0 With coma
0.000 0.400 0.599
E06.1 Subacute thyroiditis
0.000 0.405 0.595
I25.3 Aneurysm of heart
0.000 0.408 0.592
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.410 0.590
M06.0 Seronegative rheumatoid arthritis
0.000 0.410 0.590
E20-E35 Disorders of other endocrine glands
0.000 0.412 0.588
E03.1 Congenital hypothyroidism without goitre
0.000 0.422 0.577
I22.8 Subsequent myocardial infarction of other sites
0.000 0.427 0.573
I20.1 Angina pectoris with documented spasm
0.000 0.430 0.570
E06.9 Thyroiditis, unspecified
0.000 0.431 0.569
E80.6 Other disorders of bilirubin metabolism
0.000 0.435 0.565
G35-G37 Demyelinating diseases of the central nervous system
0.562 0.438 0.000
E03.8 Other specified hypothyroidism
0.000 0.439 0.561
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.442 0.558
E07 Other disorders of thyroid
0.000 0.444 0.556
G37 Other demyelinating diseases of central nervous system
0.555 0.445 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.449 0.551
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.449 0.551
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.449 0.551
E74.2 Disorders of galactose metabolism
0.000 0.449 0.551
E74.1 Disorders of fructose metabolism
0.000 0.449 0.551
E74.0 Glycogen storage disease
0.000 0.449 0.551
I23.8 Other current complications following acute myocardial infarction
0.000 0.452 0.548
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.452 0.547
I24.1 Dressler's syndrome
0.000 0.454 0.546
G37.9 Demyelinating disease of central nervous system, unspecified
0.543 0.457 0.000
E05.8 Other thyrotoxicosis
0.000 0.460 0.539
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.461 0.539
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.465 0.535
E11.8 With unspecified complications
0.000 0.465 0.535
E83.1 Disorders of iron metabolism
0.533 0.467 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.472 0.528
M06.34 Rheumatoid nodule (Hand)
0.000 0.473 0.527
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.478 0.522
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.478 0.522
E79.1 Lesch-Nyhan syndrome
0.000 0.478 0.522
E11.5 With peripheral circulatory complications
0.000 0.481 0.519
E23 Hypofunction and other disorders of pituitary gland
0.000 0.481 0.519
H36 Retinal disorders in diseases classified elsewhere
0.000 0.485 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E71.3 Disorders of fatty-acid metabolism
0.000 0.490 0.510
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.490 0.510
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.490 0.510
E71.0 Maple-syrup-urine disease
0.000 0.490 0.510
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.490 0.510
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.490 0.510
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.490 0.510
E76.2 Other mucopolysaccharidoses
0.000 0.490 0.510
E76.1 Mucopolysaccharidosis, type II
0.000 0.490 0.510
E76.0 Mucopolysaccharidosis, type I
0.000 0.490 0.510
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.490 0.510
E77.8 Other disorders of glycoprotein metabolism
0.000 0.490 0.510
E77.1 Defects in glycoprotein degradation
0.000 0.490 0.510
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.490 0.510
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.490 0.509
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.490 0.509
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.490 0.509
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.490 0.509
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.490 0.509
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.490 0.509
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.492 0.508
M06.8 Other specified rheumatoid arthritis
0.000 0.494 0.506
M06.2 Rheumatoid bursitis
0.000 0.494 0.506
M06.1 Adult-onset Still's disease
0.000 0.494 0.506
E84.8 Cystic fibrosis with other manifestations
0.000 0.495 0.504
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.495 0.504
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.495 0.504
E73.8 Other lactose intolerance
0.000 0.501 0.499
E73.1 Secondary lactase deficiency
0.000 0.501 0.499
E73.0 Congenital lactase deficiency
0.000 0.501 0.499
E84.9 Cystic fibrosis, unspecified
0.000 0.503 0.497
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.504 0.495
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.504 0.495
E70.2 Disorders of tyrosine metabolism
0.000 0.504 0.495
E70.1 Other hyperphenylalaninaemias
0.000 0.504 0.495
E70.0 Classical phenylketonuria
0.000 0.504 0.495
E75.6 Lipid storage disorder, unspecified
0.000 0.506 0.494
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.506 0.494
E75.3 Sphingolipidosis, unspecified
0.000 0.506 0.494
E75.2 Other sphingolipidosis
0.000 0.506 0.494
E75.1 Other gangliosidosis
0.000 0.506 0.494
E75.0 GM2 gangliosidosis
0.000 0.506 0.494
E23.6 Other disorders of pituitary gland
0.000 0.509 0.491
E24 Cushing's syndrome
0.000 0.510 0.490
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.514 0.486
E80.1 Porphyria cutanea tarda
0.000 0.515 0.485
E73.9 Lactose intolerance, unspecified
0.000 0.516 0.484
E80.2 Other porphyria
0.000 0.518 0.482
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.519 0.480
E80.5 Crigler-Najjar syndrome
0.000 0.519 0.480
E80.3 Defects of catalase and peroxydase
0.000 0.519 0.480
E80.0 Hereditary erythropoietic porphyria
0.000 0.519 0.480
E50-E64 Other nutritional deficiencies
0.000 0.521 0.479
K90 Intestinal malabsorption
0.000 0.522 0.478
E86 Volume depletion
0.000 0.523 0.477
E70.3 Albinism
0.000 0.525 0.475
E75.5 Other lipid storage disorders
0.000 0.529 0.471
I21.4 Acute subendocardial myocardial infarction
0.000 0.531 0.469
G37.8 Other specified demyelinating diseases of central nervous system
0.460 0.540 0.000
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.540 0.459
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.540 0.459
E72.5 Disorders of glycine metabolism
0.000 0.540 0.459
E72.4 Disorders of ornithine metabolism
0.000 0.540 0.459
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.540 0.459
E72.2 Disorders of urea cycle metabolism
0.000 0.540 0.459
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.543 0.457
M06.38 Rheumatoid nodule (Other)
0.000 0.543 0.457
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.543 0.457
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.543 0.457
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.543 0.457
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.547 0.453
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.549 0.451
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.550 0.450
E28 Ovarian dysfunction
0.000 0.550 0.450
E22 Hyperfunction of pituitary gland
0.000 0.552 0.448
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.558 0.442
E65-E68 Obesity and other hyperalimentation
0.000 0.560 0.440
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.560 0.439
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.436 0.564 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.567 0.432
E44.0 Moderate protein-energy malnutrition
0.000 0.567 0.432
E72.0 Disorders of amino-acid transport
0.000 0.568 0.432
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.577 0.423
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.577 0.423
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.577 0.423
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.577 0.423
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.577 0.423
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.577 0.422
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.579 0.421
E32 Diseases of thymus
0.000 0.579 0.421
E31 Polyglandular dysfunction
0.000 0.579 0.421
E30 Disorders of puberty, not elsewhere classified
0.000 0.579 0.421
E23.2 Diabetes insipidus
0.000 0.579 0.421
E61 Deficiency of other nutrient elements
0.000 0.582 0.418
E07.8 Other specified disorders of thyroid
0.000 0.594 0.406
E24.0 Pituitary-dependent Cushing's disease
0.000 0.595 0.405
M06.33 Rheumatoid nodule (Forearm)
0.000 0.599 0.401
E21.3 Hyperparathyroidism, unspecified
0.000 0.599 0.401
E24.2 Drug-induced Cushing's syndrome
0.000 0.600 0.400
E26 Hyperaldosteronism
0.000 0.601 0.399
E07.1 Dyshormogenetic goitre
0.000 0.601 0.398
E07.0 Hypersecretion of calcitonin
0.000 0.601 0.398
G37.5 Concentric sclerosis [Balo]
0.398 0.602 0.000
G37.4 Subacute necrotising myelitis
0.398 0.602 0.000
G37.2 Central pontine myelinolysis
0.398 0.602 0.000
G37.1 Central demyelination of corpus callosum
0.398 0.602 0.000
G37.0 Diffuse sclerosis
0.398 0.602 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.604 0.395
M06.4 Inflammatory polyarthropathy
0.000 0.609 0.391
G36 Other acute disseminated demyelination
0.388 0.611 0.000
E61.1 Iron deficiency
0.000 0.616 0.384
K90.9 Intestinal malabsorption, unspecified
0.000 0.619 0.381
E23.7 Disorder of pituitary gland, unspecified
0.000 0.623 0.377
E85 Amyloidosis
0.001 0.623 0.376
E28.2 Polycystic ovarian syndrome
0.000 0.624 0.376
E25 Adrenogenital disorders
0.000 0.626 0.374
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.628 0.372
E23.1 Drug-induced hypopituitarism
0.000 0.628 0.372
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.631 0.369
E20 Hypoparathyroidism
0.000 0.633 0.367
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.637 0.363
M06.18 Adult-onset Still's disease (Other)
0.000 0.637 0.363
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.637 0.363
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.637 0.363
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.637 0.363
M06.14 Adult-onset Still's disease (Hand)
0.000 0.637 0.363
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.637 0.363
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.637 0.363
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.637 0.363
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.637 0.363
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.637 0.363
M06.28 Rheumatoid bursitis (Other)
0.000 0.637 0.363
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.637 0.363
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.637 0.363
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.637 0.363
M06.24 Rheumatoid bursitis (Hand)
0.000 0.637 0.363
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.637 0.363
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.637 0.363
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.637 0.363
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.637 0.363
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.637 0.363
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.637 0.363
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.637 0.363
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.637 0.363
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.637 0.363
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.637 0.363
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.637 0.363
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.637 0.363
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.637 0.363
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.637 0.363
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.638 0.362
E22.0 Acromegaly and pituitary gigantism
0.000 0.639 0.361
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.643 0.357
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.648 0.352
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.648 0.352
E24.3 Ectopic ACTH syndrome
0.000 0.648 0.352
E24.1 Nelson's syndrome
0.000 0.648 0.352
E24.8 Other Cushing's syndrome
0.000 0.655 0.344
E21.2 Other hyperparathyroidism
0.000 0.656 0.344
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.656 0.343
E63 Other nutritional deficiencies
0.000 0.656 0.343
E51 Thiamine deficiency
0.000 0.656 0.343
E50 Vitamin A deficiency
0.000 0.656 0.343
E60 Dietary zinc deficiency
0.000 0.656 0.343
E59 Dietary selenium deficiency
0.000 0.656 0.343
E52 Niacin deficiency [pellagra]
0.000 0.656 0.343
K90.3 Pancreatic steatorrhoea
0.000 0.657 0.343
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.657 0.343
K90.1 Tropical sprue
0.000 0.657 0.343
E56 Other vitamin deficiencies
0.000 0.661 0.338
K90.8 Other intestinal malabsorption
0.000 0.662 0.338
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.662 0.337
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.664 0.336
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.674 0.326
E24.9 Cushing's syndrome, unspecified
0.000 0.675 0.325
E21.4 Other specified disorders of parathyroid gland
0.000 0.675 0.325
E28.9 Ovarian dysfunction, unspecified
0.000 0.677 0.322
E28.8 Other ovarian dysfunction
0.000 0.677 0.322
E28.1 Androgen excess
0.000 0.677 0.322
E28.0 Oestrogen excess
0.000 0.677 0.322
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.679 0.321
E22.8 Other hyperfunction of pituitary gland
0.000 0.679 0.321
E67 Other hyperalimentation
0.000 0.684 0.315
E68 Sequelae of hyperalimentation
0.000 0.684 0.315
E58 Dietary calcium deficiency
0.000 0.686 0.313
E65 Localised adiposity
0.000 0.687 0.313
E89.2 Postprocedural hypoparathyroidism
0.001 0.690 0.309
E83 Disorders of mineral metabolism
0.252 0.695 0.053
E30.9 Disorder of puberty, unspecified
0.000 0.698 0.302
E30.8 Other disorders of puberty
0.000 0.698 0.302
E30.1 Precocious puberty
0.000 0.698 0.302
E30.0 Delayed puberty
0.000 0.698 0.302
E31.9 Polyglandular dysfunction, unspecified
0.000 0.698 0.302
E31.8 Other polyglandular dysfunction
0.000 0.698 0.302
E31.1 Polyglandular hyperfunction
0.000 0.698 0.302
E31.0 Autoimmune polyglandular failure
0.000 0.698 0.302
E32.9 Disease of thymus, unspecified
0.000 0.698 0.302
E32.8 Other diseases of thymus
0.000 0.698 0.302
E32.1 Abscess of thymus
0.000 0.698 0.302
E32.0 Persistent hyperplasia of thymus
0.000 0.698 0.302
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.698 0.302
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.698 0.302
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.698 0.302
E61.9 Deficiency of nutrient element, unspecified
0.000 0.700 0.300
E61.8 Deficiency of other specified nutrient elements
0.000 0.700 0.300
E61.7 Deficiency of multiple nutrient elements
0.000 0.700 0.300
E61.6 Vanadium deficiency
0.000 0.700 0.300
E61.5 Molybdenum deficiency
0.000 0.700 0.300
E61.4 Chromium deficiency
0.000 0.700 0.300
E61.3 Manganese deficiency
0.000 0.700 0.300
E61.0 Copper deficiency
0.000 0.700 0.300
E29 Testicular dysfunction
0.000 0.702 0.298
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.703 0.296
E54 Ascorbic acid deficiency
0.000 0.706 0.293
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.708 0.292
E26.9 Hyperaldosteronism, unspecified
0.000 0.714 0.286
E26.8 Other hyperaldosteronism
0.000 0.714 0.286
E26.1 Secondary hyperaldosteronism
0.000 0.714 0.286
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.719 0.280
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.719 0.280
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.719 0.280
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.719 0.280
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.719 0.280
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.719 0.280
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.719 0.280
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.719 0.280
E28.3 Primary ovarian failure
0.000 0.721 0.279
G36.9 Acute disseminated demyelination, unspecified
0.279 0.721 0.000
G36.8 Other specified acute disseminated demyelination
0.279 0.721 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.279 0.721 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.730 0.270
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.730 0.270
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.730 0.270
E27 Other disorders of adrenal gland
0.000 0.731 0.269
E61.2 Magnesium deficiency
0.000 0.731 0.269
E25.9 Adrenogenital disorder, unspecified
0.000 0.732 0.268
E25.8 Other adrenogenital disorders
0.000 0.732 0.268
G36.0 Neuromyelitis optica [Devic]
0.264 0.735 0.000
E26.0 Primary hyperaldosteronism
0.000 0.736 0.264
E20.1 Pseudohypoparathyroidism
0.000 0.736 0.263
E20.0 Idiopathic hypoparathyroidism
0.000 0.736 0.263
E34 Other endocrine disorders
0.001 0.737 0.263
E50.9 Vitamin A deficiency, unspecified
0.000 0.753 0.246
E50.8 Other manifestations of vitamin A deficiency
0.000 0.753 0.246
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.753 0.246
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.753 0.246
E50.5 Vitamin A deficiency with night blindness
0.000 0.753 0.246
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.753 0.246
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.753 0.246
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.753 0.246
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.753 0.246
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.753 0.246
E51.9 Thiamine deficiency, unspecified
0.000 0.753 0.246
E51.8 Other manifestations of thiamine deficiency
0.000 0.753 0.246
E51.2 Wernicke's encephalopathy
0.000 0.753 0.246
E51.1 Beriberi
0.000 0.753 0.246
E63.9 Nutritional deficiency, unspecified
0.000 0.753 0.246
E63.8 Other specified nutritional deficiencies
0.000 0.753 0.246
E63.1 Imbalance of constituents of food intake
0.000 0.753 0.246
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.753 0.246
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.753 0.246
E64.8 Sequelae of other nutritional deficiencies
0.000 0.753 0.246
E64.3 Sequelae of rickets
0.000 0.753 0.246
E64.2 Sequelae of vitamin C deficiency
0.000 0.753 0.246
E64.1 Sequelae of vitamin A deficiency
0.000 0.753 0.246
E64.0 Sequelae of protein-energy malnutrition
0.000 0.753 0.246
E20.9 Hypoparathyroidism, unspecified
0.000 0.756 0.244
E56.9 Vitamin deficiency, unspecified
0.000 0.757 0.243
E56.8 Deficiency of other vitamins
0.000 0.757 0.243
E56.0 Deficiency of vitamin E
0.000 0.757 0.243
E85.4 Organ-limited amyloidosis
0.000 0.757 0.242
E80.4 Gilbert's syndrome
0.000 0.760 0.240
E56.1 Deficiency of vitamin K
0.000 0.762 0.238
E55 Vitamin D deficiency
0.000 0.762 0.238
E27.9 Disorder of adrenal gland, unspecified
0.000 0.763 0.237
E20.8 Other hypoparathyroidism
0.000 0.765 0.234
E22.1 Hyperprolactinaemia
0.000 0.767 0.232
E83.9 Disorder of mineral metabolism, unspecified
0.199 0.768 0.033
E85.8 Other amyloidosis
0.001 0.772 0.227
E67.8 Other specified hyperalimentation
0.000 0.774 0.226

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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