TreeWAS – Variant ID: rs16991453

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
I20 Angina pectoris	0.999	0.001	0.000
I20.9 Angina pectoris, unspecified	0.999	0.001	0.000
I25.2 Old myocardial infarction	0.997	0.003	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.994	0.006	0.000
I21.9 Acute myocardial infarction, unspecified	0.985	0.015	0.000
I24 Other acute ischaemic heart diseases	0.966	0.034	0.000
I25.5 Ischaemic cardiomyopathy	0.954	0.046	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.950	0.050	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.943	0.057	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.898	0.102	0.000
I22 Subsequent myocardial infarction	0.884	0.116	0.000
I20.0 Unstable angina	0.825	0.175	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.799	0.201	0.000
I25.6 Silent myocardial ischaemia	0.797	0.203	0.000
I25.3 Aneurysm of heart	0.793	0.207	0.000
I25.4 Coronary artery aneurysm	0.719	0.281	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
I22.8 Subsequent myocardial infarction of other sites	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.705	0.295	0.000
I24.1 Dressler's syndrome	0.693	0.307	0.000
I24.8 Other forms of acute ischaemic heart disease	0.668	0.332	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.648	0.352	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.634	0.366	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.619	0.381	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.581	0.419	0.000
I20.1 Angina pectoris with documented spasm	0.576	0.423	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.574	0.426	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.539	0.461	0.000
I20.8 Other forms of angina pectoris	0.514	0.486	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.506	0.494	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.506	0.494	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.506	0.494	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.506	0.494	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.506	0.494	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.506	0.494	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.506	0.494	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.500	0.499	0.001
I23.8 Other current complications following acute myocardial infarction	0.494	0.506	0.000
I21.4 Acute subendocardial myocardial infarction	0.474	0.526	0.000
Z95.1 Presence of aortocoronary bypass graft	0.319	0.681	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.237	0.763	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.217	0.783	0.000
Z95.0 Presence of cardiac pacemaker	0.163	0.837	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.131	0.869	0.000
Z95.4 Presence of other heart-valve replacement	0.097	0.903	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.055	0.945	0.000
Z95.2 Presence of prosthetic heart valve	0.053	0.947	0.000
Z95.3 Presence of xenogenic heart valve	0.052	0.947	0.001
N84.1 Polyp of cervix uteri	0.000	0.990	0.010
N36.8 Other specified disorders of urethra	0.009	0.991	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.992	0.008
Z43.2 Attention to ileostomy	0.008	0.992	0.000
I71 Aortic aneurysm and dissection	0.000	0.993	0.007
A04.7 Enterocolitis due to Clostridium difficile	0.007	0.993	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.993	0.007
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.993	0.007
Q50.4 Embryonic cyst of Fallopian tube	0.006	0.994	0.000
I74 Arterial embolism and thrombosis	0.000	0.994	0.006
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.994	0.006
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.994	0.006
I78 Diseases of capillaries	0.000	0.994	0.006
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.994	0.005
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.994	0.005
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.994	0.005
I71.0 Dissection of aorta [any part]	0.000	0.995	0.005
I78.1 Naevus, nonneoplastic	0.000	0.995	0.005
A04 Other bacterial intestinal infections	0.005	0.995	0.000
G43.9 Migraine, unspecified	0.000	0.995	0.005
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.995	0.005
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.995	0.005
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.995	0.005
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.995	0.005
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.005	0.995	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.995	0.005
Z43 Attention to artificial openings	0.005	0.995	0.000
A04.8 Other specified bacterial intestinal infections	0.005	0.995	0.000
I78.8 Other diseases of capillaries	0.000	0.995	0.005
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.995	0.005
Z43.1 Attention to gastrostomy	0.005	0.995	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.995	0.005
G61.0 Guillain-Barre syndrome	0.005	0.995	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.995	0.005
A04.4 Other intestinal Escherichia coli infections	0.005	0.995	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.995	0.005
Z43.5 Attention to cyctostomy	0.005	0.995	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.995	0.004
A04.9 Bacterial intestinal infection, unspecified	0.004	0.996	0.000
A04.5 Campylobacter enteritis	0.004	0.996	0.000
N36 Other disorders of urethra	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.996	0.004
C71.2 Temporal lobe	0.004	0.996	0.000
N36.9 Urethral disorder, unspecified	0.004	0.996	0.000
Z43.0 Attention to tracheostomy	0.004	0.996	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.004	0.996	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.004	0.996	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.004	0.996	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.004	0.996	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.004	0.996	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.004	0.996	0.000
M31.6 Other giant cell arteritis	0.000	0.996	0.004
K76.6 Portal hypertension	0.000	0.996	0.004
Q53 Undescended testicle	0.004	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.996	0.004
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.004	0.996	0.000
Q50.5 Embryonic cyst of broad ligament	0.004	0.996	0.000
Q50.3 Other congenital malformations of ovary	0.004	0.996	0.000
Q50.2 Congenital torsion of ovary	0.004	0.996	0.000
Q50.1 Developmental ovarian cyst	0.004	0.996	0.000
Q50.0 Congenital absence of ovary	0.004	0.996	0.000
Q53.1 Undescended testicle, unilateral	0.004	0.996	0.000
B07 Viral warts	0.000	0.996	0.004
N36.0 Urethral fistula	0.004	0.996	0.000
Z43.9 Attention to unspecified artificial opening	0.004	0.996	0.000
Z43.7 Attention to artificial vagina	0.004	0.996	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.004	0.996	0.000
Q52 Other congenital malformations of female genitalia	0.004	0.996	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.996	0.004
G30.9 Alzheimer's disease, unspecified	0.004	0.996	0.000
Q54.0 Hypospadias, balanic	0.004	0.996	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.003	0.996	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.997	0.003
S52.80 Fracture of other parts of forearm (closed)	0.003	0.997	0.000
Z43.8 Attention to other artificial openings	0.003	0.997	0.000
I70 Atherosclerosis	0.000	0.997	0.003
Q52.1 Doubling of vagina	0.003	0.997	0.000
Q54.9 Hypospadias, unspecified	0.003	0.997	0.000
G24.9 Dystonia, unspecified	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.003	0.997	0.000
Q53.0 Ectopic testis	0.003	0.997	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.003	0.997	0.000
Q54.8 Other hypospadias	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
Q54.1 Hypospadias, penile	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.003	0.997	0.000
G44.0 Cluster headache syndrome	0.000	0.997	0.003
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.003	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.997	0.000
Q52.5 Fusion of labia	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
Q52.3 Imperforate hymen	0.003	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.997	0.000
Q52.0 Congenital absence of vagina	0.003	0.997	0.000
N36.2 Urethral caruncle	0.003	0.997	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.003
I79.1 Aortitis in diseases classified elsewhere	0.000	0.997	0.003
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.997	0.003
N36.1 Urethral diverticulum	0.003	0.997	0.000
K76 Other diseases of liver	0.000	0.997	0.003
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
G43 Migraine	0.000	0.997	0.003
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.997	0.003
I70.1 Atherosclerosis of renal artery	0.000	0.997	0.003
O63.1 Prolonged second stage (of labour)	0.003	0.997	0.000
W22.9 Unspecified place	0.000	0.997	0.003
Z43.3 Attention to colostomy	0.003	0.997	0.000
K76.9 Liver disease, unspecified	0.000	0.997	0.003
D22.5 Melanocytic naevi of trunk	0.000	0.997	0.003
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.997	0.000
Q55.6 Other congenital malformations of penis	0.002	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.997	0.000
Q55.3 Atresia of vas deferens	0.002	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.997	0.000
Q55.0 Absence and aplasia of testis	0.002	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.997	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.003	0.997	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.997	0.002
I70.8 Atherosclerosis of other arteries	0.000	0.997	0.002
N36.3 Prolapsed urethral mucosa	0.002	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.997	0.003
G44.8 Other specified headache syndromes	0.000	0.997	0.003
H18.6 Keratoconus	0.003	0.997	0.000
D25.0 Submucous leiomyoma of uterus	0.003	0.997	0.000
Q51.2 Other doubling of uterus	0.002	0.997	0.000
S51.8 Open wound of other parts of forearm	0.002	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.997	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.997	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.997	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.997	0.000
Q51.4 Unicornate uterus	0.002	0.997	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.997	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.997	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.998	0.002
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
K76.7 Hepatorenal syndrome	0.000	0.998	0.002
G43.0 Migraine without aura [common migraine]	0.000	0.998	0.002
G30 Alzheimer's disease	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.002	0.998	0.000
G44 Other headache syndromes	0.000	0.998	0.002
G44.2 Tension-type headache	0.000	0.998	0.002
K76.5 Hepatic veno-occlusive disease	0.000	0.998	0.002
K76.4 Peliosis hepatis	0.000	0.998	0.002
K76.3 Infarction of liver	0.000	0.998	0.002
K76.2 Central haemorrhagic necrosis of liver	0.000	0.998	0.002
K76.1 Chronic passive congestion of liver	0.000	0.998	0.002
Q51.3 Bicornate uterus	0.002	0.998	0.000
G43.3 Complicated migraine	0.000	0.998	0.002
G43.2 Status migrainosus	0.000	0.998	0.002
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.998	0.002
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.002	0.998	0.000
K90.0 Coeliac disease	0.000	0.998	0.002
G30.1 Alzheimer's disease with late onset	0.002	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.998	0.002
I70.0 Atherosclerosis of aorta	0.000	0.998	0.002
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.998	0.002
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.998	0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.998	0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.998	0.002
M31 Other necrotising vasculopathies	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
M31.3 Wegener's granulomatosis	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.998	0.002
K90.9 Intestinal malabsorption, unspecified	0.000	0.998	0.002
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
G43.8 Other migraine	0.000	0.998	0.002
G30.8 Other Alzheimer's disease	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.002	0.998	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
C71.9 Brain, unspecified	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.998	0.002
L29.9 Pruritus, unspecified	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.998	0.002
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
E83.5 Disorders of calcium metabolism	0.000	0.998	0.002
G44.3 Chronic posttraumatic headache	0.000	0.998	0.002
M31.8 Other specified necrotising vasculopathies	0.000	0.998	0.002
M31.7 Microscopic polyangiitis	0.000	0.998	0.002
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.998	0.002
M31.2 Lethal midline granuloma	0.000	0.998	0.002
M31.1 Thrombotic microangiopathy	0.000	0.998	0.002
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
G44.1 Vascular headache, not elsewhere classified	0.000	0.998	0.002
H18.2 Other corneal oedema	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.998	0.002
G61.1 Serum neuropathy	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
N84 Polyp of female genital tract	0.000	0.998	0.002
Q66 Congenital deformities of feet	0.002	0.998	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
M31.0 Hypersensitivity angiitis	0.000	0.998	0.002
Z75.1 Person awaiting admission to adequate facility elsewhere	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.998	0.002
R00.2 Palpitations	0.000	0.998	0.002
G24 Dystonia	0.002	0.998	0.000
I72 Other aneurysm	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
H53.9 Visual disturbance, unspecified	0.002	0.998	0.000
M31.9 Necrotising vasculopathy, unspecified	0.000	0.998	0.002
O20.9 Haemorrhage in early pregnancy, unspecified	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
G24.5 Blepharospasm	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.001	0.998	0.000
Q67.7 Pectus carinatum	0.001	0.998	0.000
Q67.6 Pectus excavatum	0.001	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.998	0.000
Q67.3 Plagiocephaly	0.001	0.998	0.000
Q67.2 Dolichocephaly	0.001	0.998	0.000
Q67.1 Compression facies	0.001	0.998	0.000
Q67.0 Facial asymmetry	0.001	0.998	0.000
S52.8 Fracture of other parts of forearm	0.002	0.998	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
H92.0 Otalgia	0.002	0.998	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.998	0.002
R10.1 Pain localised to upper abdomen	0.000	0.998	0.002
E78.2 Mixed hyperlipidaemia	0.000	0.998	0.002
M20.2 Hallux rigidus	0.000	0.998	0.002
M43.1 Spondylolisthesis	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.001
S92.31 Fracture of metatarsal bone (open)	0.001	0.998	0.000
Q27.4 Congenital phlebectasia	0.001	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.998	0.000
Q78 Other osteochondrodysplasias	0.001	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.001	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.001	0.998	0.000
Q73 Reduction defects of unspecified limb	0.001	0.998	0.000
Q72 Reduction defects of lower limb	0.001	0.998	0.000
Q71 Reduction defects of upper limb	0.001	0.998	0.000
Q70 Syndactyly	0.001	0.998	0.000
Q69 Polydactyly	0.001	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.001	0.998	0.000
C71.1 Frontal lobe	0.001	0.998	0.000
I89.0 Lymphoedema, not elsewhere classified	0.002	0.998	0.000
N84.3 Polyp of vulva	0.000	0.998	0.002
Q37 Cleft palate with cleft lip	0.001	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.998	0.000
N48.1 Balanoposthitis	0.002	0.998	0.000
K90 Intestinal malabsorption	0.000	0.998	0.002
S92 Fracture of foot, except ankle	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.998	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.001	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.001	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.998	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.001	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.998	0.000
Q66.7 Pes cavus	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.2 Metatarsus varus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
Q66.0 Talipes equinovarus	0.001	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.001	0.998	0.000
M60.08 Infective myositis (Other)	0.001	0.998	0.000
G24.4 Idiopathic orofacial dystonia	0.001	0.998	0.000
G24.2 Idiopathic nonfamilial dystonia	0.001	0.998	0.000
G24.1 Idiopathic familial dystonia	0.001	0.998	0.000
G24.0 Drug-induced dystonia	0.001	0.998	0.000
H18.8 Other specified disorders of cornea	0.001	0.998	0.000
H18.7 Other corneal deformities	0.001	0.998	0.000
H18.3 Changes in corneal membranes	0.001	0.998	0.000
O43.8 Other placental disorders	0.000	0.998	0.001
Q24.5 Malformation of coronary vessels	0.001	0.998	0.000
Q76.0 Spina bifida occulta	0.001	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.998	0.002
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.998	0.001
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.998	0.001
I72.1 Aneurysm of artery of upper extremity	0.000	0.998	0.001
Q25 Congenital malformations of great arteries	0.001	0.998	0.000
N43.3 Hydrocele, unspecified	0.000	0.998	0.002
Q22.5 Ebstein's anomaly	0.001	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.998	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.001	0.998	0.000
I77 Other disorders of arteries and arterioles	0.000	0.998	0.001
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.001	0.998	0.000
M43.12 Spondylolisthesis (Cervical region)	0.000	0.999	0.001
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.001	0.999	0.000
Q76.8 Other congenital malformations of bony thorax	0.001	0.999	0.000
Q76.7 Congenital malformation of sternum	0.001	0.999	0.000
Q76.6 Other congenital malformations of ribs	0.001	0.999	0.000
Q76.5 Cervical rib	0.001	0.999	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.001	0.999	0.000
Q76.2 Congenital spondylolisthesis	0.001	0.999	0.000
Q76.1 Klippel-Feil syndrome	0.001	0.999	0.000
Q36 Cleft lip	0.001	0.999	0.000
Q35 Cleft palate	0.001	0.999	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.001	0.999	0.001
S52.81 Fracture of other parts of forearm (open)	0.001	0.999	0.000
E78.4 Other hyperlipidaemia	0.000	0.999	0.001
G24.8 Other dystonia	0.001	0.999	0.000
G24.3 Spasmodic torticollis	0.001	0.999	0.000
I72.2 Aneurysm of renal artery	0.000	0.999	0.001
N84.2 Polyp of vagina	0.000	0.999	0.001
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.001	0.999	0.000
Q82.2 Mastocytosis	0.001	0.999	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.999	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.999	0.001
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.999	0.001
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.999	0.001
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.999	0.001
S92.71 Multiple fractures of foot (open)	0.001	0.999	0.000
G61.8 Other inflammatory polyneuropathies	0.001	0.999	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.999	0.001
N84.8 Polyp of other parts of female genital tract	0.000	0.999	0.001
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.001	0.999	0.000
Q25.0 Patent ductus arteriosus	0.001	0.999	0.000
Q44.6 Cystic disease of liver	0.001	0.999	0.000
S92.2 Fracture of other tarsal bone(s)	0.001	0.999	0.000
Q26 Congenital malformations of great veins	0.001	0.999	0.000
Q24 Other congenital malformations of heart	0.001	0.999	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.001	0.999	0.000
H20.8 Other iridocyclitis	0.001	0.999	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.999	0.001
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.999	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.999	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.999	0.000
Q68.3 Congenital bowing of femur	0.001	0.999	0.000
Q68.2 Congenital deformity of knee	0.001	0.999	0.000
Q68.1 Congenital deformity of hand	0.001	0.999	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.999	0.000
Q69.9 Polydactyly, unspecified	0.001	0.999	0.000
Q69.2 Accessory toe(s)	0.001	0.999	0.000
Q69.1 Accessory thumb(s)	0.001	0.999	0.000
Q69.0 Accessory finger(s)	0.001	0.999	0.000
Q70.9 Syndactyly, unspecified	0.001	0.999	0.000
Q70.4 Polysyndactyly	0.001	0.999	0.000
Q70.3 Webbed toes	0.001	0.999	0.000
Q70.2 Fused toes	0.001	0.999	0.000
Q70.1 Webbed fingers	0.001	0.999	0.000
Q70.0 Fused fingers	0.001	0.999	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.999	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.999	0.000
Q71.6 Lobster-claw hand	0.001	0.999	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.999	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.999	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.999	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.999	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.999	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.999	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.999	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.999	0.000
Q72.7 Split foot	0.001	0.999	0.000
Q72.6 Longitudinal reduction defect of fibula	0.001	0.999	0.000
Q72.5 Longitudinal reduction defect of tibia	0.001	0.999	0.000
Q72.4 Longitudinal reduction defect of femur	0.001	0.999	0.000
Q72.3 Congenital absence of foot and toe(s)	0.001	0.999	0.000
Q72.2 Congenital absence of both lower leg and foot	0.001	0.999	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.001	0.999	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.001	0.999	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.001	0.999	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.001	0.999	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.001	0.999	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.001	0.999	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.001	0.999	0.000
Q74.3 Arthrogryposis multiplex congenita	0.001	0.999	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.999	0.000
Q74.1 Congenital malformation of knee	0.001	0.999	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.001	0.999	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.999	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.999	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.999	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.999	0.000
Q75.3 Macrocephaly	0.001	0.999	0.000
Q75.2 Hypertelorism	0.001	0.999	0.000
Q75.1 Craniofacial dysostosis	0.001	0.999	0.000
Q75.0 Craniosynostosis	0.001	0.999	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.001	0.999	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.999	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.001	0.999	0.000
Q77.6 Chondroectodermal dysplasia	0.001	0.999	0.000
Q77.5 Diastrophic dysplasia	0.001	0.999	0.000
Q77.4 Achondroplasia	0.001	0.999	0.000
Q77.3 Chondrodysplasia punctata	0.001	0.999	0.000
Q77.2 Short rib syndrome	0.001	0.999	0.000
Q77.1 Thanatophoric short stature	0.001	0.999	0.000
Q77.0 Achondrogenesis	0.001	0.999	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.001	0.999	0.000
Q78.8 Other specified osteochondrodysplasias	0.001	0.999	0.000
Q78.6 Multiple congenital exostoses	0.001	0.999	0.000
Q78.5 Metaphyseal dysplasia	0.001	0.999	0.000
Q78.4 Enchondromatosis	0.001	0.999	0.000
Q78.3 Progressive diaphyseal dysplasia	0.001	0.999	0.000
Q78.2 Osteopetrosis	0.001	0.999	0.000
Q78.1 Polyostotic fibrous dysplasia	0.001	0.999	0.000
Q78.0 Osteogenesis imperfecta	0.001	0.999	0.000
Q07 Other congenital malformations of nervous system	0.001	0.999	0.000
Q28 Other congenital malformations of circulatory system	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations