TreeWAS – Variant ID: rs1704223

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.000	1.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.001	0.999
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.001	0.999
I22 Subsequent myocardial infarction	0.000	0.002	0.998
I20.9 Angina pectoris, unspecified	0.000	0.002	0.998
I25.2 Old myocardial infarction	0.000	0.002	0.998
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.006	0.994
I20.8 Other forms of angina pectoris	0.000	0.007	0.993
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.022	0.978
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.023	0.977
I25.5 Ischaemic cardiomyopathy	0.000	0.027	0.973
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.027	0.973
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.086	0.914
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.099	0.901
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.101	0.899
I22.8 Subsequent myocardial infarction of other sites	0.000	0.126	0.874
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.131	0.869
I24 Other acute ischaemic heart diseases	0.000	0.185	0.815
I25.3 Aneurysm of heart	0.000	0.195	0.805
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.225	0.775
I20.0 Unstable angina	0.000	0.245	0.755
Z95.0 Presence of cardiac pacemaker	0.000	0.262	0.738
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.327	0.673
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.338	0.662
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.351	0.649
I23 Certain current complications following acute myocardial infarction	0.000	0.362	0.638
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.386	0.614
Z95.3 Presence of xenogenic heart valve	0.000	0.392	0.608
I24.1 Dressler's syndrome	0.000	0.416	0.584
I24.8 Other forms of acute ischaemic heart disease	0.000	0.432	0.568
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.451	0.549
I20.1 Angina pectoris with documented spasm	0.000	0.453	0.547
I25.4 Coronary artery aneurysm	0.000	0.461	0.538
I21.4 Acute subendocardial myocardial infarction	0.000	0.538	0.462
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.542	0.458
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.542	0.458
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.542	0.458
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.542	0.458
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.542	0.458
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.542	0.458
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.542	0.458
I23.8 Other current complications following acute myocardial infarction	0.000	0.621	0.379
E11 Non-insulin-dependent diabetes mellitus	0.000	0.723	0.277
E11.2 With renal complications	0.000	0.733	0.267
S61 Open wound of wrist and hand	0.000	0.734	0.266
E11.3 With ophthalmic complications	0.000	0.741	0.259
E11.4 With neurological complications	0.000	0.743	0.257
S60-S69 Injuries to the wrist and hand	0.000	0.746	0.254
S61.8 Open wound of other parts of wrist and hand	0.000	0.749	0.251
S61.1 Open wound of finger(s) with damage to nail	0.000	0.757	0.243
S61.7 Multiple open wounds of wrist and hand	0.000	0.759	0.241
E11.1 With ketoacidosis	0.000	0.763	0.237
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.767	0.233
E11.5 With peripheral circulatory complications	0.000	0.768	0.232
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.768	0.232
E11.6 With other specified complications	0.000	0.769	0.231
S64 Injury of nerves at wrist and hand level	0.000	0.777	0.223
E11.8 With unspecified complications	0.000	0.782	0.218
S68 Traumatic amputation of wrist and hand	0.000	0.786	0.214
E10-E14 Diabetes mellitus	0.000	0.789	0.211
S69 Other and unspecified injuries of wrist and hand	0.000	0.795	0.205
S64.4 Injury of digital nerve of other finger	0.000	0.798	0.202
E11.0 With coma	0.000	0.798	0.202
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.799	0.201
S67 Crushing injury of wrist and hand	0.000	0.799	0.200
S61.0 Open wound of finger(s) without damage to nail	0.000	0.800	0.200
E11.7 With multiple complications	0.000	0.801	0.199
S60 Superficial injury of wrist and hand	0.000	0.802	0.198
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.805	0.195
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.807	0.193
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.811	0.189
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.811	0.189
E13 Other specified diabetes mellitus	0.000	0.812	0.188
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.816	0.184
S65 Injury of blood vessels at wrist and hand level	0.000	0.818	0.182
E20-E35 Disorders of other endocrine glands	0.000	0.818	0.182
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.823	0.177
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.826	0.174
E11.9 Without complications	0.000	0.826	0.174
E13.9 Without complications	0.000	0.829	0.171
S69.9 Unspecified injury of wrist and hand	0.000	0.831	0.169
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.833	0.167
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.833	0.167
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.834	0.166
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.834	0.166
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.834	0.166
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.840	0.160
S64.8 Injury of other nerves at wrist and hand level	0.000	0.840	0.160
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.840	0.160
S64.1 Injury of median nerve at wrist and hand level	0.000	0.840	0.160
E70-E90 Metabolic disorders	0.000	0.841	0.159
S63.6 Sprain and strain of finger(s)	0.000	0.841	0.159
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.842	0.158
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.842	0.158
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.842	0.157
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.843	0.157
E24 Cushing's syndrome	0.000	0.844	0.156
S62 Fracture at wrist and hand level	0.000	0.845	0.155
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.845	0.155
E22 Hyperfunction of pituitary gland	0.000	0.845	0.154
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.846	0.154
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.846	0.154
S68.4 Traumatic amputation of hand at wrist level	0.000	0.846	0.154
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.846	0.154
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.847	0.153
E27 Other disorders of adrenal gland	0.000	0.848	0.152
S64.3 Injury of digital nerve of thumb	0.000	0.848	0.152
E12 Malnutrition-related diabetes mellitus	0.000	0.848	0.151
S69.8 Other specified injuries of wrist and hand	0.000	0.853	0.147
S69.7 Multiple injuries of wrist and hand	0.000	0.853	0.147
R79.8 Other specified abnormal findings of blood chemistry	0.000	0.855	0.145
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.856	0.144
E20 Hypoparathyroidism	0.000	0.856	0.144
S62.6 Fracture of other finger	0.000	0.857	0.143
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.857	0.143
Z95.2 Presence of prosthetic heart valve	0.001	0.857	0.143
E23 Hypofunction and other disorders of pituitary gland	0.000	0.857	0.143
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.857	0.143
S60.0 Contusion of finger(s) without damage to nail	0.000	0.857	0.142
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.858	0.142
S60.8 Other superficial injuries of wrist and hand	0.000	0.858	0.142
S60.7 Multiple superficial injuries of wrist and hand	0.000	0.858	0.142
S60.1 Contusion of finger(s) with damage to nail	0.000	0.858	0.142
E87.2 Acidosis	0.000	0.859	0.141
E00-E07 Disorders of thyroid gland	0.000	0.860	0.140
E26 Hyperaldosteronism	0.000	0.860	0.139
E83 Disorders of mineral metabolism	0.000	0.861	0.139
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.861	0.139
E87.7 Fluid overload	0.000	0.861	0.139
S63.1 Dislocation finger	0.000	0.861	0.139
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.861	0.139
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.861	0.139
S63.2 Multiple dislocations of fingers	0.000	0.861	0.139
E24.9 Cushing's syndrome, unspecified	0.000	0.862	0.138
S62.60 Fracture of other finger (closed)	0.000	0.863	0.137
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.863	0.137
E21.0 Primary hyperparathyroidism	0.000	0.863	0.137
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.865	0.135
S63.0 Dislocation of wrist	0.000	0.865	0.135
E13.8 With unspecified complications	0.000	0.865	0.135
E13.7 With multiple complications	0.000	0.865	0.135
E13.6 With other specified complications	0.000	0.865	0.135
E13.5 With peripheral circulatory complications	0.000	0.865	0.135
E13.4 With neurological complications	0.000	0.865	0.135
E13.3 With ophthalmic complications	0.000	0.865	0.135
E13.2 With renal complications	0.000	0.865	0.135
E13.1 With ketoacidosis	0.000	0.865	0.135
E13.0 With coma	0.000	0.865	0.135
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.867	0.133
E34 Other endocrine disorders	0.000	0.867	0.133
E05.9 Thyrotoxicosis, unspecified	0.000	0.868	0.132
E50-E64 Other nutritional deficiencies	0.000	0.869	0.131
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.869	0.131
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.869	0.131
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.869	0.131
S65.5 Injury of blood vessel(s) of other finger	0.000	0.869	0.131
S65.4 Injury of blood vessel(s) of thumb	0.000	0.869	0.131
S65.3 Injury of deep palmar arch	0.000	0.869	0.131
S65.2 Injury of superficial palmar arch	0.000	0.869	0.131
S65.1 Injury of radial artery at wrist and hand level	0.000	0.869	0.131
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.869	0.131
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.869	0.131
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.869	0.130
E32 Diseases of thymus	0.000	0.869	0.130
E31 Polyglandular dysfunction	0.000	0.869	0.130
E30 Disorders of puberty, not elsewhere classified	0.000	0.869	0.130
E25 Adrenogenital disorders	0.000	0.869	0.130
E29 Testicular dysfunction	0.000	0.871	0.129
E78.0 Pure hypercholesterolaemia	0.000	0.874	0.126
S62.3 Fracture of other metacarpal bone	0.000	0.874	0.125
E83.5 Disorders of calcium metabolism	0.000	0.877	0.123
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.877	0.123
S63.5 Sprain and strain of wrist	0.000	0.877	0.122
E22.1 Hyperprolactinaemia	0.000	0.878	0.122
S60.2 Contusion of other parts of wrist and hand	0.000	0.878	0.122
E87.3 Alkalosis	0.000	0.880	0.120
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.881	0.119
E83.3 Disorders of phosphorus metabolism	0.000	0.881	0.119
E40-E46 Malnutrition	0.000	0.882	0.118
E20.9 Hypoparathyroidism, unspecified	0.000	0.883	0.117
E23.0 Hypopituitarism	0.000	0.883	0.117
E74 Other disorders of carbohydrate metabolism	0.000	0.883	0.116
E87.0 Hyperosmolality and hypernatraemia	0.000	0.884	0.116
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.885	0.115
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.886	0.114
E84 Cystic fibrosis	0.000	0.886	0.114
E79 Disorders of purine and pyrimidine metabolism	0.000	0.886	0.114
E77 Disorders of glycoprotein metabolism	0.000	0.886	0.114
E76 Disorders of glycosaminoglycan metabolism	0.000	0.886	0.114
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.886	0.114
E72 Other disorders of amino-acid metabolism	0.000	0.886	0.114
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.886	0.114
E70 Disorders of aromatic amino-acid metabolism	0.000	0.886	0.114
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.886	0.114
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.886	0.114
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.887	0.113
E24.8 Other Cushing's syndrome	0.000	0.888	0.112
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.888	0.112
E24.3 Ectopic ACTH syndrome	0.000	0.888	0.112
E24.2 Drug-induced Cushing's syndrome	0.000	0.888	0.112
E24.1 Nelson's syndrome	0.000	0.888	0.112
E24.0 Pituitary-dependent Cushing's disease	0.000	0.888	0.112
S62.1 Fracture of other carpal bone(s)	0.000	0.889	0.111
E87.4 Mixed disorder of acid-base balance	0.000	0.889	0.111
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.889	0.111
E22.8 Other hyperfunction of pituitary gland	0.000	0.889	0.111
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.890	0.110
E21.4 Other specified disorders of parathyroid gland	0.000	0.890	0.110
E21.2 Other hyperparathyroidism	0.000	0.890	0.110
E27.1 Primary adrenocortical insufficiency	0.000	0.890	0.110
E73 Lactose intolerance	0.000	0.891	0.109
E26.0 Primary hyperaldosteronism	0.000	0.891	0.109
E27.5 Adrenomedullary hyperfunction	0.000	0.891	0.109
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.891	0.109
E27.0 Other adrenocortical overactivity	0.000	0.891	0.109
E12.9 Without complications	0.000	0.891	0.109
E12.8 With unspecified complications	0.000	0.891	0.109
E12.7 With multiple complications	0.000	0.891	0.109
E12.6 With other specified complications	0.000	0.891	0.109
E12.5 With peripheral circulatory complications	0.000	0.891	0.109
E12.4 With neurological complications	0.000	0.891	0.109
E12.3 With ophthalmic complications	0.000	0.891	0.109
E12.2 With renal complications	0.000	0.891	0.109
E12.1 With ketoacidosis	0.000	0.891	0.109
E12.0 With coma	0.000	0.891	0.109
E23.6 Other disorders of pituitary gland	0.000	0.891	0.109
E27.2 Addisonian crisis	0.000	0.893	0.107
E27.8 Other specified disorders of adrenal gland	0.000	0.893	0.106
E27.9 Disorder of adrenal gland, unspecified	0.000	0.894	0.106
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.895	0.105
E78.1 Pure hyperglyceridaemia	0.000	0.896	0.104
S62.4 Multiple fractures of metacarpal bones	0.000	0.897	0.103
E20.8 Other hypoparathyroidism	0.000	0.897	0.103
E20.1 Pseudohypoparathyroidism	0.000	0.897	0.103
E20.0 Idiopathic hypoparathyroidism	0.000	0.897	0.103
E23.7 Disorder of pituitary gland, unspecified	0.000	0.897	0.103
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.897	0.103
E23.1 Drug-induced hypopituitarism	0.000	0.897	0.103
E78.8 Other disorders of lipoprotein metabolism	0.000	0.897	0.103
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.899	0.101
E00 Congenital iodine-deficiency syndrome	0.000	0.899	0.101
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.899	0.101
E85 Amyloidosis	0.000	0.899	0.101
E28 Ovarian dysfunction	0.000	0.900	0.100
E26.9 Hyperaldosteronism, unspecified	0.000	0.900	0.100
E26.8 Other hyperaldosteronism	0.000	0.900	0.100
E26.1 Secondary hyperaldosteronism	0.000	0.900	0.100
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.900	0.100
E83.8 Other disorders of mineral metabolism	0.000	0.900	0.100
E83.2 Disorders of zinc metabolism	0.000	0.900	0.100
E83.0 Disorders of copper metabolism	0.000	0.900	0.100
E05.8 Other thyrotoxicosis	0.000	0.900	0.100
E05.5 Thyroid crisis or storm	0.000	0.900	0.100
E05.4 Thyrotoxicosis factitia	0.000	0.900	0.100
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.900	0.100
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.900	0.100
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.900	0.100
Z95.4 Presence of other heart-valve replacement	0.002	0.900	0.098
E34.9 Endocrine disorder, unspecified	0.000	0.902	0.098
E78.4 Other hyperlipidaemia	0.000	0.902	0.098
E53 Deficiency of other B group vitamins	0.000	0.902	0.098
E65-E68 Obesity and other hyperalimentation	0.000	0.902	0.097
E83.4 Disorders of magnesium metabolism	0.000	0.903	0.097
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.904	0.096
S62.2 Fracture of first metacarpal bone	0.000	0.904	0.096
E34.8 Other specified endocrine disorders	0.000	0.904	0.096
E34.5 Androgen resistance syndrome	0.000	0.904	0.096
E34.4 Constitutional tall stature	0.000	0.904	0.096
E34.3 Short stature, not elsewhere classified	0.000	0.904	0.096
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.904	0.096
E34.1 Other hypersecretion of intestinal hormones	0.000	0.904	0.096
E34.0 Carcinoid syndrome	0.000	0.904	0.096
E22.0 Acromegaly and pituitary gigantism	0.000	0.904	0.095
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.905	0.095
E55 Vitamin D deficiency	0.000	0.905	0.095
E10 Insulin-dependent diabetes mellitus	0.000	0.905	0.095
E21.3 Hyperparathyroidism, unspecified	0.000	0.905	0.095
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.906	0.094
E63 Other nutritional deficiencies	0.000	0.906	0.094
E56 Other vitamin deficiencies	0.000	0.906	0.094
E51 Thiamine deficiency	0.000	0.906	0.094
E50 Vitamin A deficiency	0.000	0.906	0.094
E60 Dietary zinc deficiency	0.000	0.906	0.094
E59 Dietary selenium deficiency	0.000	0.906	0.094
E58 Dietary calcium deficiency	0.000	0.906	0.094
E54 Ascorbic acid deficiency	0.000	0.906	0.094
E52 Niacin deficiency [pellagra]	0.000	0.906	0.094
E78.6 Lipoprotein deficiency	0.000	0.906	0.094
E78.3 Hyperchylomicronaemia	0.000	0.906	0.094
E25.9 Adrenogenital disorder, unspecified	0.000	0.906	0.094
E25.8 Other adrenogenital disorders	0.000	0.906	0.094
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.906	0.094
E30.9 Disorder of puberty, unspecified	0.000	0.906	0.094
E30.8 Other disorders of puberty	0.000	0.906	0.094
E30.1 Precocious puberty	0.000	0.906	0.094
E30.0 Delayed puberty	0.000	0.906	0.094
E31.9 Polyglandular dysfunction, unspecified	0.000	0.906	0.094
E31.8 Other polyglandular dysfunction	0.000	0.906	0.094
E31.1 Polyglandular hyperfunction	0.000	0.906	0.094
E31.0 Autoimmune polyglandular failure	0.000	0.906	0.094
E32.9 Disease of thymus, unspecified	0.000	0.906	0.094
E32.8 Other diseases of thymus	0.000	0.906	0.094
E32.1 Abscess of thymus	0.000	0.906	0.094
E32.0 Persistent hyperplasia of thymus	0.000	0.906	0.094
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.906	0.094
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.906	0.094
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.906	0.094
E23.2 Diabetes insipidus	0.000	0.907	0.093
S62.61 Fracture of other finger (open)	0.000	0.907	0.093
E29.9 Testicular dysfunction, unspecified	0.000	0.907	0.093
E29.8 Other testicular dysfunction	0.000	0.907	0.093
E29.0 Testicular hyperfunction	0.000	0.907	0.093
E29.1 Testicular hypofunction	0.000	0.908	0.092
S62.31 Fracture of other metacarpal bone (open)	0.000	0.910	0.090
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.911	0.088
E61 Deficiency of other nutrient elements	0.000	0.912	0.088
E88 Other metabolic disorders	0.000	0.912	0.088
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.913	0.087
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.914	0.086
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.915	0.085
E45 Retarded development following protein-energy malnutrition	0.000	0.915	0.085
E43 Unspecified severe protein-energy malnutrition	0.000	0.915	0.085
E42 Marasmic kwashiorkor	0.000	0.915	0.085
E41 Nutritional marasmus	0.000	0.915	0.085
E40 Kwashiorkor	0.000	0.915	0.085
S62.7 Multiple fractures of fingers	0.001	0.915	0.085
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.915	0.085
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.916	0.084
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.916	0.084
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.916	0.084
E74.2 Disorders of galactose metabolism	0.000	0.916	0.084
E74.1 Disorders of fructose metabolism	0.000	0.916	0.084
E74.0 Glycogen storage disease	0.000	0.916	0.084
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.918	0.082
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.918	0.082
E70.3 Albinism	0.000	0.918	0.082
E70.2 Disorders of tyrosine metabolism	0.000	0.918	0.082
E70.1 Other hyperphenylalaninaemias	0.000	0.918	0.082
E70.0 Classical phenylketonuria	0.000	0.918	0.082
E71.3 Disorders of fatty-acid metabolism	0.000	0.918	0.082
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.918	0.082
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.918	0.082
E71.0 Maple-syrup-urine disease	0.000	0.918	0.082
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.918	0.082
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.918	0.082
E72.5 Disorders of glycine metabolism	0.000	0.918	0.082
E72.4 Disorders of ornithine metabolism	0.000	0.918	0.082
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.918	0.082
E72.2 Disorders of urea cycle metabolism	0.000	0.918	0.082
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.918	0.082
E72.0 Disorders of amino-acid transport	0.000	0.918	0.082
E75.6 Lipid storage disorder, unspecified	0.000	0.918	0.082
E75.5 Other lipid storage disorders	0.000	0.918	0.082
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.918	0.082
E75.3 Sphingolipidosis, unspecified	0.000	0.918	0.082
E75.2 Other sphingolipidosis	0.000	0.918	0.082
E75.1 Other gangliosidosis	0.000	0.918	0.082
E75.0 GM2 gangliosidosis	0.000	0.918	0.082
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.918	0.082
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.918	0.082
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.918	0.082
E76.2 Other mucopolysaccharidoses	0.000	0.918	0.082
E76.1 Mucopolysaccharidosis, type II	0.000	0.918	0.082
E76.0 Mucopolysaccharidosis, type I	0.000	0.918	0.082
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.918	0.082
E77.8 Other disorders of glycoprotein metabolism	0.000	0.918	0.082
E77.1 Defects in glycoprotein degradation	0.000	0.918	0.082
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.918	0.082
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.918	0.082
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.918	0.082
E79.1 Lesch-Nyhan syndrome	0.000	0.918	0.082
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.918	0.082
E84.9 Cystic fibrosis, unspecified	0.000	0.918	0.082
E84.8 Cystic fibrosis with other manifestations	0.000	0.918	0.082
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.918	0.082
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.918	0.082
E15 Nondiabetic hypoglycaemic coma	0.000	0.919	0.081
E10.1 With ketoacidosis	0.000	0.919	0.081
E87.5 Hyperkalaemia	0.000	0.920	0.080
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.920	0.080
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.920	0.080
S62.5 Fracture of thumb	0.000	0.920	0.080
E83.1 Disorders of iron metabolism	0.000	0.921	0.079
E73.8 Other lactose intolerance	0.000	0.921	0.078
E73.1 Secondary lactase deficiency	0.000	0.921	0.078
E73.0 Congenital lactase deficiency	0.000	0.921	0.078
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.922	0.078
E53.8 Deficiency of other specified B group vitamins	0.000	0.923	0.076
E04 Other non-toxic goitre	0.000	0.924	0.076
E14 Unspecified diabetes mellitus	0.000	0.924	0.076
Z82.3 Family history of stroke	0.000	0.925	0.075
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.926	0.074
E10.4 With neurological complications	0.000	0.926	0.074
E73.9 Lactose intolerance, unspecified	0.000	0.926	0.074
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.927	0.072
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.927	0.072
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.927	0.072
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.927	0.072
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.927	0.072
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.927	0.072
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.927	0.072
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.927	0.072
E85.8 Other amyloidosis	0.000	0.927	0.072
E85.3 Secondary systemic amyloidosis	0.000	0.927	0.072
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.927	0.072
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.927	0.072
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.927	0.072
E28.9 Ovarian dysfunction, unspecified	0.000	0.928	0.072
E28.8 Other ovarian dysfunction	0.000	0.928	0.072
E28.1 Androgen excess	0.000	0.928	0.072
E28.0 Oestrogen excess	0.000	0.928	0.072
E46 Unspecified protein-energy malnutrition	0.000	0.929	0.071
E28.3 Primary ovarian failure	0.000	0.929	0.070
E53.1 Pyridoxine deficiency	0.000	0.930	0.070
E53.0 Riboflavin deficiency	0.000	0.930	0.070
E07 Other disorders of thyroid	0.000	0.930	0.070
E67 Other hyperalimentation	0.000	0.930	0.070
E68 Sequelae of hyperalimentation	0.000	0.930	0.070
E10.8 With unspecified complications	0.000	0.930	0.070
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.931	0.069
S62.21 Fracture of first metacarpal bone (open)	0.000	0.931	0.069
E55.9 Vitamin D deficiency, unspecified	0.000	0.931	0.069
E04.2 Non-toxic multinodular goitre	0.000	0.931	0.069
E78.2 Mixed hyperlipidaemia	0.000	0.931	0.068
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.931	0.068
E80.6 Other disorders of bilirubin metabolism	0.000	0.931	0.068
E80.5 Crigler-Najjar syndrome	0.000	0.931	0.068
E80.3 Defects of catalase and peroxydase	0.000	0.931	0.068
E80.2 Other porphyria	0.000	0.931	0.068
E80.1 Porphyria cutanea tarda	0.000	0.931	0.068
E80.0 Hereditary erythropoietic porphyria	0.000	0.931	0.068
E55.0 Rickets, active	0.000	0.932	0.068
E10.7 With multiple complications	0.000	0.932	0.068
E10.6 With other specified complications	0.000	0.932	0.068
E10.0 With coma	0.000	0.932	0.068
E65 Localised adiposity	0.000	0.932	0.068
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.932	0.068
E50.9 Vitamin A deficiency, unspecified	0.000	0.932	0.068
E50.8 Other manifestations of vitamin A deficiency	0.000	0.932	0.068
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.932	0.068
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.932	0.068
E50.5 Vitamin A deficiency with night blindness	0.000	0.932	0.068
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.932	0.068
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.932	0.068
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.932	0.068
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.932	0.068
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.932	0.068
E51.9 Thiamine deficiency, unspecified	0.000	0.932	0.068
E51.8 Other manifestations of thiamine deficiency	0.000	0.932	0.068
E51.2 Wernicke's encephalopathy	0.000	0.932	0.068
E51.1 Beriberi	0.000	0.932	0.068
E56.9 Vitamin deficiency, unspecified	0.000	0.932	0.068
E56.8 Deficiency of other vitamins	0.000	0.932	0.068
E56.1 Deficiency of vitamin K	0.000	0.932	0.068
E56.0 Deficiency of vitamin E	0.000	0.932	0.068
E63.9 Nutritional deficiency, unspecified	0.000	0.932	0.068
E63.8 Other specified nutritional deficiencies	0.000	0.932	0.068
E63.1 Imbalance of constituents of food intake	0.000	0.932	0.068
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.932	0.068
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.932	0.068
E64.8 Sequelae of other nutritional deficiencies	0.000	0.932	0.068
E64.3 Sequelae of rickets	0.000	0.932	0.068
E64.2 Sequelae of vitamin C deficiency	0.000	0.932	0.068
E64.1 Sequelae of vitamin A deficiency	0.000	0.932	0.068
E64.0 Sequelae of protein-energy malnutrition	0.000	0.932	0.068
E85.9 Amyloidosis, unspecified	0.000	0.932	0.067
E03 Other hypothyroidism	0.000	0.933	0.067
E53.9 Vitamin B deficiency, unspecified	0.000	0.933	0.067
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.933	0.066
E89.0 Postprocedural hypothyroidism	0.000	0.934	0.066
E10.3 With ophthalmic complications	0.000	0.934	0.066
E85.4 Organ-limited amyloidosis	0.000	0.935	0.065
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.936	0.064
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.936	0.064
E61.9 Deficiency of nutrient element, unspecified	0.000	0.936	0.063
E61.8 Deficiency of other specified nutrient elements	0.000	0.936	0.063
E61.7 Deficiency of multiple nutrient elements	0.000	0.936	0.063
E61.6 Vanadium deficiency	0.000	0.936	0.063
E61.5 Molybdenum deficiency	0.000	0.936	0.063
E61.4 Chromium deficiency	0.000	0.936	0.063
E61.3 Manganese deficiency	0.000	0.936	0.063
E61.2 Magnesium deficiency	0.000	0.936	0.063
E61.0 Copper deficiency	0.000	0.936	0.063
E06 Thyroiditis	0.001	0.936	0.063
E88.9 Metabolic disorder, unspecified	0.000	0.937	0.063
E88.8 Other specified metabolic disorders	0.000	0.937	0.063
E88.3 Tumour lysis syndrome	0.000	0.937	0.063
E88.2 Lipomatosis, not elsewhere classified	0.000	0.937	0.063
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.937	0.063
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.937	0.063
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.937	0.063
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.937	0.063

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations