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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0208
log Bayes Factor = 40.6733
contains 2 variants:
rs75818885
lBF = 10.272
Chr 2 : 56,351,058
rs61736521
lBF = 25.372
Chr19 : 56,206,311
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
R06 Abnormalities of breathing
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
J18 Pneumonia, organism unspecified
0.999 0.001 0.000
J18.1 Lobar pneumonia, unspecified
0.999 0.001 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.999 0.001 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.999 0.001 0.000
R06.0 Dyspnoea
0.998 0.002 0.000
R79 Other abnormal findings of blood chemistry
0.998 0.002 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.998 0.002 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
I25 Chronic ischaemic heart disease
0.996 0.004 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.995 0.005 0.000
R94 Abnormal results of function studies
0.995 0.005 0.000
I20 Angina pectoris
0.994 0.006 0.000
R94.5 Abnormal results of liver function studies
0.993 0.007 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.993 0.007 0.000
F41 Other anxiety disorders
0.993 0.007 0.000
M70-M79 Other soft tissue disorders
0.991 0.009 0.000
M54 Dorsalgia
0.990 0.010 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.990 0.010 0.000
R07 Pain in throat and chest
0.990 0.010 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.989 0.011 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
R07.4 Chest pain, unspecified
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.986 0.014 0.000
I73 Other peripheral vascular diseases
0.986 0.014 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.986 0.014 0.000
I25.1 Atherosclerotic heart disease
0.985 0.015 0.000
I20.9 Angina pectoris, unspecified
0.981 0.019 0.000
M10 Gout
0.979 0.021 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.976 0.024 0.000
F41.9 Anxiety disorder, unspecified
0.975 0.025 0.000
J40-J47 Chronic lower respiratory diseases
0.974 0.026 0.000
R02 Gangrene, not elsewhere classified
0.972 0.028 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.971 0.029 0.000
S80-S89 Injuries to the knee and lower leg
0.970 0.030 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.970 0.030 0.000
R06.8 Other and unspecified abnormalities of breathing
0.969 0.031 0.000
S90-S99 Injuries to the ankle and foot
0.969 0.031 0.000
I73.9 Peripheral vascular disease, unspecified
0.968 0.032 0.000
M10.9 Gout, unspecified
0.965 0.035 0.000
I20.0 Unstable angina
0.964 0.036 0.000
E78.0 Pure hypercholesterolaemia
0.963 0.037 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.960 0.040 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.960 0.040 0.000
F41.2 Mixed anxiety and depressive disorder
0.960 0.040 0.000
T92 Sequelae of injuries of upper limb
0.955 0.045 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.954 0.046 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.950 0.050 0.000
I78 Diseases of capillaries
0.949 0.051 0.000
E70-E90 Metabolic disorders
0.948 0.052 0.000
M10.99 Gout, unspecified (Site unspecified)
0.948 0.052 0.000
M51 Other intervertebral disk disorders
0.947 0.053 0.000
I05-I09 Chronic rheumatic heart diseases
0.943 0.057 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.943 0.057 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.940 0.060 0.000
T42.4 Benzodiazepines
0.938 0.062 0.000
M79.0 Rheumatism, unspecified
0.938 0.062 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.936 0.064 0.000
M79.8 Other specified soft tissue disorders
0.936 0.064 0.000
I71 Aortic aneurysm and dissection
0.935 0.065 0.000
E00-E07 Disorders of thyroid gland
0.933 0.067 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.932 0.068 0.000
I51 Complications and ill-defined descriptions of heart disease
0.931 0.069 0.000
I22 Subsequent myocardial infarction
0.931 0.069 0.000
R87 Abnormal findings in specimens from female genital organs
0.930 0.070 0.000
M54.4 Lumbago with sciatica
0.928 0.072 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.927 0.073 0.000
Y57 Other and unspecified drugs and medicaments
0.924 0.076 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.922 0.078 0.000
I74 Arterial embolism and thrombosis
0.922 0.078 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.921 0.079 0.000
M40-M43 Deforming dorsopathies
0.920 0.080 0.000
S82 Fracture of lower leg, including ankle
0.919 0.081 0.000
I34 Nonrheumatic mitral valve disorders
0.919 0.081 0.000
D80-D89 Certain disorders involving the immune mechanism
0.916 0.084 0.000
I78.1 Naevus, nonneoplastic
0.913 0.087 0.000
Y60.0 During surgical operation
0.912 0.088 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.912 0.088 0.000
T43.2 Other and unspecified antidepressants
0.911 0.089 0.000
S92 Fracture of foot, except ankle
0.911 0.089 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.910 0.090 0.000
J90-J94 Other diseases of pleura
0.910 0.090 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.908 0.092 0.000
E04 Other non-toxic goitre
0.907 0.093 0.000
M51.2 Other specified intervertebral disk displacement
0.907 0.093 0.000
J43 Emphysema
0.906 0.094 0.000
R47-R49 Symptoms and signs involving speech and voice
0.904 0.096 0.000
I51.9 Heart disease, unspecified
0.903 0.097 0.000
M45-M49 Spondylopathies
0.902 0.098 0.000
M54.9 Dorsalgia, unspecified
0.900 0.100 0.000
M54.5 Low back pain
0.899 0.101 0.000
R87.6 Abnormal cytological findings
0.898 0.102 0.000
R74 Abnormal serum enzyme levels
0.898 0.102 0.000
T66-T78 Other and unspecified effects of external causes
0.897 0.103 0.000
I34.0 Mitral (valve) insufficiency
0.897 0.103 0.000
M65-M68 Disorders of synovium and tendon
0.897 0.103 0.000
R05 Cough
0.896 0.104 0.000
I33 Acute and subacute endocarditis
0.892 0.108 0.000
Q80-Q89 Other congenital malformations
0.892 0.108 0.000
D86 Sarcoidosis
0.889 0.111 0.000
I50 Heart failure
0.884 0.116 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.884 0.116 0.000
J93 Pneumothorax
0.884 0.116 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.881 0.119 0.000
E04.2 Non-toxic multinodular goitre
0.879 0.121 0.000
E65-E68 Obesity and other hyperalimentation
0.876 0.124 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.876 0.124 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.875 0.125 0.000
G90-G99 Other disorders of the nervous system
0.874 0.126 0.000
M91-M94 Chondropathies
0.872 0.128 0.000
M86-M90 Other osteopathies
0.872 0.128 0.000
I50.1 Left ventricular failure
0.872 0.128 0.000
M79.7 Fibromyalgia
0.868 0.132 0.000
M79.88 Other specified soft tissue disorders (Other)
0.865 0.135 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.864 0.136 0.000
T93 Sequelae of injuries of lower limb
0.862 0.138 0.000
I74.5 Embolism and thrombosis of iliac artery
0.860 0.140 0.000
M46 Other inflammatory spondylopathies
0.859 0.141 0.000
J30-J39 Other diseases of upper respiratory tract
0.858 0.142 0.000
J43.9 Emphysema, unspecified
0.857 0.143 0.000
J93.1 Other spontaneous pneumothorax
0.856 0.144 0.000
Y40 Systemic antibiotics
0.856 0.144 0.000
D86.9 Sarcoidosis, unspecified
0.853 0.147 0.000
M41 Scoliosis
0.852 0.148 0.000
R06.1 Stridor
0.850 0.150 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.849 0.151 0.000
I08 Multiple valve diseases
0.849 0.151 0.000
S82.5 Fracture of medial malleolus
0.848 0.152 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.847 0.153 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.845 0.155 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.844 0.156 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.844 0.156 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.843 0.157 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.842 0.158 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.842 0.158 0.000
J60-J70 Lung diseases due to external agents
0.842 0.158 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.841 0.159 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.839 0.161 0.000
E04.9 Non-toxic goitre, unspecified
0.837 0.163 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.837 0.163 0.000
G70-G73 Diseases of myoneural junction and muscle
0.834 0.166 0.000
S82.4 Fracture of fibula alone
0.834 0.166 0.000
S83.2 Tear of meniscus, current
0.833 0.167 0.000
J44 Other chronic obstructive pulmonary disease
0.832 0.168 0.000
T78 Adverse effects, not elsewhere classified
0.832 0.168 0.000
M06.3 Rheumatoid nodule
0.832 0.168 0.000
S82.3 Fracture of lower end of tibia
0.831 0.168 0.000
G40-G47 Episodic and paroxysmal disorders
0.832 0.168 0.000
Y57.5 X-ray contrast media
0.831 0.169 0.000
S92.0 Fracture of calcaneus
0.831 0.169 0.000
S70-S79 Injuries to the hip and thigh
0.830 0.170 0.000
R50-R69 General symptoms and signs
0.828 0.172 0.000
R74.8 Abnormal levels of other serum enzymes
0.826 0.174 0.000
I33.0 Acute and subacute infective endocarditis
0.825 0.175 0.000
X60-X84 Intentional self-harm
0.825 0.175 0.000
I72 Other aneurysm
0.825 0.175 0.000
Y00-Y09 Assault
0.822 0.177 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.821 0.179 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.821 0.179 0.000
R94.6 Abnormal results of thyroid function studies
0.820 0.180 0.000
J92 Pleural plaque
0.819 0.181 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.819 0.181 0.000
M54.59 Low back pain (Site unspecified)
0.818 0.182 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.818 0.182 0.000
I07 Rheumatic tricuspid valve diseases
0.817 0.183 0.000
R63 Symptoms and signs concerning food and fluid intake
0.817 0.183 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.817 0.183 0.000
M79.6 Pain in limb
0.817 0.183 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.814 0.186 0.000
J39 Other diseases of upper respiratory tract
0.811 0.189 0.000
S91 Open wound of ankle and foot
0.811 0.189 0.000
R69 Unknown and unspecified causes of morbidity
0.810 0.190 0.000
I47 Paroxysmal tachycardia
0.810 0.190 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.808 0.192 0.000
Y43 Primarily systemic agents
0.808 0.192 0.000
T92.0 Sequelae of open wound of upper limb
0.806 0.194 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.806 0.194 0.000
R86 Abnormal findings in specimens from male genital organs
0.805 0.195 0.000
M79.2 Neuralgia and neuritis, unspecified
0.805 0.195 0.000
J42 Unspecified chronic bronchitis
0.805 0.195 0.000
M41.9 Scoliosis, unspecified
0.804 0.196 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.804 0.196 0.000
M20-M25 Other joint disorders
0.803 0.197 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.803 0.197 0.000
Y46.2 Hydantoin derivatives
0.803 0.197 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.802 0.198 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.802 0.198 0.000
J46 Status asthmaticus
0.802 0.198 0.000
J35 Chronic diseases of tonsils and adenoids
0.801 0.199 0.000
M65 Synovitis and tenosynovitis
0.800 0.200 0.000
R63.4 Abnormal weight loss
0.799 0.201 0.000
R49 Voice disturbances
0.799 0.201 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.799 0.201 0.000
I08.0 Disorders of both mitral and aortic valves
0.799 0.201 0.000
S82.50 Fracture of medial malleolus (closed)
0.798 0.202 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.798 0.202 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.798 0.202 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.797 0.203 0.000
G30-G32 Other degenerative diseases of the nervous system
0.797 0.203 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.797 0.203 0.000
J47 Bronchiectasis
0.797 0.203 0.000
E66 Obesity
0.795 0.205 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.795 0.205 0.000
M54.56 Low back pain (Lumbar region)
0.793 0.207 0.000
Q85 Phakomatoses, not elsewhere classified
0.792 0.208 0.000
R04 Haemorrhage from respiratory passages
0.791 0.209 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.790 0.210 0.000
J92.9 Pleural plaque without asbestos
0.790 0.210 0.000
Y52 Agents primarily affecting the cardiovascular system
0.789 0.211 0.000
I71.0 Dissection of aorta [any part]
0.789 0.211 0.000
T92.1 Sequelae of fracture of arm
0.788 0.212 0.000
J30 Vasomotor and allergic rhinitis
0.787 0.213 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.787 0.213 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.786 0.214 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.786 0.214 0.000
M54.6 Pain in thoracic spine
0.786 0.214 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.784 0.216 0.000
I73.0 Raynaud's syndrome
0.784 0.216 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.781 0.219 0.000
I42 Cardiomyopathy
0.779 0.221 0.000
I73.8 Other specified peripheral vascular diseases
0.779 0.221 0.000
E88 Other metabolic disorders
0.779 0.221 0.000
M14 Arthropathies in other diseases classified elsewhere
0.778 0.222 0.000
M60-M63 Disorders of muscles
0.778 0.222 0.000
M51.9 Intervertebral disk disorder, unspecified
0.778 0.222 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.777 0.223 0.000
M80-M85 Disorders of bone density and structure
0.777 0.223 0.000
M71 Other bursopathies
0.777 0.223 0.000
M06.0 Seronegative rheumatoid arthritis
0.777 0.223 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.777 0.223 0.000
R06.4 Hyperventilation
0.777 0.223 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.775 0.225 0.000
T98 Sequelae of other and unspecified effects of external causes
0.774 0.225 0.000
S92.00 Fracture of calcaneus (closed)
0.773 0.227 0.000
R71 Abnormality of red blood cells
0.773 0.227 0.000
Y57.9 Drug or medicament, unspecified
0.773 0.227 0.000
S82.40 Fracture of fibula alone (closed)
0.773 0.227 0.000
Y48 Anaesthetics and therapeutic gases
0.772 0.228 0.000
M07 Psoriatic and enteropathic arthropathies
0.772 0.228 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.770 0.230 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.770 0.230 0.000
F70-F79 Mental retardation
0.770 0.230 0.000
Y44 Agents primarily affecting blood constituents
0.770 0.230 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.768 0.231 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.767 0.233 0.000
S86 Injury of muscle and tendon at lower leg level
0.767 0.233 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.767 0.233 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.766 0.234 0.000
J17 Pneumonia in diseases classified elsewhere
0.765 0.235 0.000
J14 Pneumonia due to Haemophilus influenzae
0.765 0.235 0.000
I37 Pulmonary valve disorders
0.765 0.235 0.000
M79.1 Myalgia
0.763 0.237 0.000
S82.30 Fracture of lower end of tibia (closed)
0.763 0.237 0.000
M79.70 Fibromyalgia (Multiple sites)
0.762 0.238 0.000
S83.7 Injury to multiple structures of knee
0.761 0.239 0.000
M79.69 Pain in limb (Site unspecified)
0.761 0.239 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.760 0.240 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.759 0.241 0.000
J00-J06 Acute upper respiratory infections
0.759 0.241 0.000
J40 Bronchitis, not specified as acute or chronic
0.757 0.243 0.000
S10-S19 Injuries to the neck
0.755 0.244 0.000
R79.0 Abnormal level of blood mineral
0.755 0.245 0.000
E85 Amyloidosis
0.755 0.245 0.000
F80-F89 Disorders of psychological development
0.755 0.245 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.755 0.245 0.000
M79.64 Pain in limb (Hand)
0.754 0.246 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.754 0.246 0.000
E40-E46 Malnutrition
0.753 0.247 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.753 0.247 0.000
S92.3 Fracture of metatarsal bone
0.752 0.248 0.000
M13 Other arthritis
0.752 0.248 0.000
Y40.0 Penicillins
0.752 0.248 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.750 0.249 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.750 0.250 0.000
I30 Acute pericarditis
0.749 0.251 0.000
V40-V49 Car occupant injured in transport accident
0.748 0.252 0.000
I51.6 Cardiovascular disease, unspecified
0.748 0.252 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.747 0.252 0.000
J39.2 Other diseases of pharynx
0.747 0.253 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.747 0.253 0.000
E78.8 Other disorders of lipoprotein metabolism
0.746 0.254 0.000
I51.0 Cardiac septal defect, acquired
0.746 0.254 0.000
M54.1 Radiculopathy
0.746 0.254 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.744 0.256 0.000
V80-V89 Other land transport accidents
0.743 0.257 0.000
F60-F69 Disorders of adult personality and behaviour
0.743 0.257 0.000
W50-W64 Exposure to animate mechanical forces
0.742 0.258 0.000
R04.2 Haemoptysis
0.742 0.258 0.000
M34 Systemic sclerosis
0.741 0.259 0.000
R63.0 Anorexia
0.741 0.259 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.740 0.260 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.739 0.261 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.739 0.261 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.738 0.262 0.000
M94 Other disorders of cartilage
0.738 0.262 0.000
M76 Enthesopathies of lower limb, excluding foot
0.737 0.263 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.736 0.264 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.735 0.265 0.000
R47 Speech disturbances, not elsewhere classified
0.735 0.265 0.000
R52 Pain, not elsewhere classified
0.734 0.266 0.000
F99-F99 Unspecified mental disorder
0.734 0.266 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.733 0.266 0.000
T90 Sequelae of injuries of head
0.733 0.267 0.000
F41.1 Generalised anxiety disorder
0.733 0.267 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.731 0.269 0.000
X50-X57 Overexertion, travel and privation
0.729 0.271 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.728 0.272 0.000
D60-D64 Aplastic and other anaemias
0.728 0.272 0.000
I07.1 Tricuspid insufficiency
0.727 0.273 0.000
J35.1 Hypertrophy of tonsils
0.726 0.274 0.000
M40 Kyphosis and lordosis
0.725 0.275 0.000
M89 Other disorders of bone
0.725 0.275 0.000
R61 Hyperhidrosis
0.724 0.276 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.724 0.276 0.000
M87 Osteonecrosis
0.724 0.276 0.000
J30.3 Other allergic rhinitis
0.723 0.276 0.000
X20-X29 Contact with venomous animals and plants
0.723 0.277 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.723 0.277 0.000
F42 Obsessive-compulsive disorder
0.722 0.278 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.722 0.278 0.000
J18.0 Bronchopneumonia, unspecified
0.722 0.278 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.722 0.278 0.000
R20 Disturbances of skin sensation
0.722 0.278 0.000
D86.0 Sarcoidosis of lung
0.722 0.278 0.000
R49.0 Dysphonia
0.722 0.278 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.720 0.280 0.000
I36 Nonrheumatic tricuspid valve disorders
0.720 0.280 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.720 0.280 0.000
I74.8 Embolism and thrombosis of other arteries
0.720 0.280 0.000
T91 Sequelae of injuries of neck and trunk
0.719 0.280 0.000
S89 Other and unspecified injuries of lower leg
0.719 0.281 0.000
J10 Influenza due to identified influenza virus
0.719 0.281 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.719 0.281 0.000
T93.1 Sequelae of fracture of femur
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
J09 Influenza due to certain identified influenza virus
0.717 0.283 0.000
J12 Viral pneumonia, not elsewhere classified
0.717 0.283 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.4 Inflammatory polyarthropathy
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
R07.0 Pain in throat
0.717 0.283 0.000
R06.3 Periodic breathing
0.717 0.283 0.000
R06.7 Sneezing
0.717 0.283 0.000
I45 Other conduction disorders
0.717 0.283 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.716 0.284 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.716 0.284 0.000
J18.2 Hypostatic pneumonia, unspecified
0.716 0.284 0.000
J18.8 Other pneumonia, organism unspecified
0.716 0.284 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.716 0.284 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.716 0.284 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.716 0.284 0.000
R77 Other abnormalities of plasma proteins
0.716 0.284 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.716 0.284 0.000
M92 Other juvenile osteochondrosis
0.716 0.284 0.000
Y43.1 Antineoplastic antimetabolites
0.716 0.284 0.000
M66 Spontaneous rupture of synovium and tendon
0.715 0.284 0.000
Q83 Congenital malformations of breast
0.715 0.284 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.715 0.285 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.715 0.285 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.715 0.285 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.715 0.285 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
Y58 Bacterial vaccines
0.715 0.285 0.000
Y59 Other and unspecified vaccines and biological substances
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.714 0.286 0.000
I25.4 Coronary artery aneurysm
0.714 0.286 0.000
I25.6 Silent myocardial ischaemia
0.714 0.286 0.000
I47.1 Supraventricular tachycardia
0.714 0.286 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.714 0.286 0.000
T43.6 Psychostimulants with abuse potential
0.714 0.286 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.714 0.286 0.000
T43.9 Psychotropic drug, unspecified
0.714 0.286 0.000
G96 Other disorders of central nervous system
0.713 0.287 0.000
R94.0 Abnormal results of function studies of central nervous system
0.713 0.287 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.713 0.287 0.000
R94.2 Abnormal results of pulmonary function studies
0.713 0.287 0.000
R94.7 Abnormal results of other endocrine function studies
0.713 0.287 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.713 0.287 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.713 0.287 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.712 0.288 0.000
F44 Dissociative [conversion] disorders
0.712 0.288 0.000
F48 Other neurotic disorders
0.712 0.288 0.000
F41.3 Other mixed anxiety disorders
0.712 0.288 0.000
F41.8 Other specified anxiety disorders
0.712 0.288 0.000
M54.2 Cervicalgia
0.711 0.289 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.711 0.289 0.000
I51.4 Myocarditis, unspecified
0.710 0.290 0.000
M54.0 Panniculitis affecting regions of neck and back
0.710 0.290 0.000
M54.8 Other dorsalgia
0.710 0.290 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.710 0.290 0.000
M79.3 Panniculitis, unspecified
0.709 0.290 0.000
M79.9 Soft tissue disorder, unspecified
0.709 0.290 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.709 0.291 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.709 0.291 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.709 0.291 0.000
Y43.4 Immunosuppressive agents
0.709 0.291 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.709 0.291 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.709 0.291 0.000
T95 Sequelae of burns, corrosions and frostbite
0.709 0.291 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.707 0.293 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.707 0.293 0.000
I40 Acute myocarditis
0.707 0.293 0.000
I41 Myocarditis in diseases classified elsewhere
0.707 0.293 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.707 0.293 0.000
I48 Atrial fibrillation and flutter
0.707 0.293 0.000
I52 Other heart disorders in diseases classified elsewhere
0.707 0.293 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.707 0.293 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.707 0.293 0.000
I25.3 Aneurysm of heart
0.706 0.294 0.000
T79-T79 Certain early complications of trauma
0.706 0.294 0.000
R07.3 Other chest pain
0.706 0.294 0.000
Y54.5 Other diuretics
0.706 0.294 0.000
T78.4 Allergy, unspecified
0.705 0.295 0.000
M10.96 Gout, unspecified (Lower leg)
0.705 0.295 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.704 0.296 0.000
R23 Other skin changes
0.704 0.296 0.000
J93.9 Pneumothorax, unspecified
0.704 0.296 0.000
M00-M03 Infectious arthropathies
0.704 0.296 0.000
G44 Other headache syndromes
0.703 0.297 0.000
Q89 Other congenital malformations, not elsewhere classified
0.703 0.297 0.000
T93.2 Sequelae of other fractures of lower limb
0.703 0.297 0.000
G35 Multiple sclerosis
0.703 0.297 0.000
G95 Other diseases of spinal cord
0.702 0.298 0.000
M10.0 Idiopathic gout
0.702 0.298 0.000
M10.1 Lead-induced gout
0.702 0.298 0.000
M10.2 Drug-induced gout
0.702 0.298 0.000
M10.3 Gout due to impairment of renal function
0.702 0.298 0.000
M10.4 Other secondary gout
0.702 0.298 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.701 0.299 0.000
M24 Other specific joint derangements
0.701 0.299 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.701 0.299 0.000
S99 Other and unspecified injuries of ankle and foot
0.700 0.300 0.000
I20.1 Angina pectoris with documented spasm
0.700 0.300 0.000
R83 Abnormal findings in cerebrospinal fluid
0.699 0.300 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.699 0.300 0.000
M21 Other acquired deformities of limbs
0.699 0.301 0.000
I05 Rheumatic mitral valve diseases
0.699 0.301 0.000
J41 Simple and mucopurulent chronic bronchitis
0.699 0.301 0.000
M65.8 Other synovitis and tenosynovitis
0.698 0.302 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.698 0.302 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.698 0.302 0.000
G41 Status epilepticus
0.698 0.302 0.000
G71 Primary disorders of muscles
0.697 0.303 0.000
T42.0 Hydantoin derivatives
0.696 0.304 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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