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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61736521
log Bayes Factor = 25.3724
Chromosome 19   position 56,206,311  (GRCh37) Explore rs61736521 on Ensembl!
Variant rs61736521 is part of Cluster X0208

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
J09-J18 Influenza and pneumonia
1.000 0.000 0.000
J18.1 Lobar pneumonia, unspecified
1.000 0.000 0.000
J18 Pneumonia, organism unspecified
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.988 0.012 0.000
M70-M79 Other soft tissue disorders
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.985 0.015 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.985 0.015 0.000
R94 Abnormal results of function studies
0.984 0.016 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.984 0.016 0.000
R94.5 Abnormal results of liver function studies
0.983 0.017 0.000
I20 Angina pectoris
0.982 0.018 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.982 0.018 0.000
E78.0 Pure hypercholesterolaemia
0.982 0.018 0.000
F41 Other anxiety disorders
0.978 0.022 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.977 0.023 0.000
I71 Aortic aneurysm and dissection
0.977 0.023 0.000
I20.0 Unstable angina
0.976 0.024 0.000
E70-E90 Metabolic disorders
0.976 0.024 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.973 0.027 0.000
R79 Other abnormal findings of blood chemistry
0.971 0.029 0.000
J40-J47 Chronic lower respiratory diseases
0.971 0.029 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.968 0.032 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.967 0.033 0.000
R50-R69 General symptoms and signs
0.967 0.033 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.966 0.034 0.000
M10 Gout
0.963 0.037 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.961 0.039 0.000
R69 Unknown and unspecified causes of morbidity
0.957 0.043 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.956 0.044 0.000
I25 Chronic ischaemic heart disease
0.956 0.044 0.000
I78 Diseases of capillaries
0.955 0.045 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.953 0.047 0.000
I50 Heart failure
0.952 0.048 0.000
F17.1 Harmful use
0.952 0.048 0.000
I47 Paroxysmal tachycardia
0.950 0.050 0.000
M79.8 Other specified soft tissue disorders
0.949 0.051 0.000
M10.9 Gout, unspecified
0.948 0.052 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.945 0.055 0.000
Chapter VI Diseases of the nervous system
0.943 0.057 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.938 0.062 0.000
R06 Abnormalities of breathing
0.931 0.069 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.929 0.071 0.000
R05 Cough
0.929 0.071 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.927 0.073 0.000
T66-T78 Other and unspecified effects of external causes
0.926 0.074 0.000
I78.1 Naevus, nonneoplastic
0.925 0.075 0.000
M10.99 Gout, unspecified (Site unspecified)
0.925 0.075 0.000
M79.0 Rheumatism, unspecified
0.923 0.077 0.000
K70-K77 Diseases of liver
0.922 0.078 0.000
J47 Bronchiectasis
0.920 0.080 0.000
I47.1 Supraventricular tachycardia
0.918 0.082 0.000
K76 Other diseases of liver
0.917 0.083 0.000
J30-J39 Other diseases of upper respiratory tract
0.913 0.087 0.000
Chapter XI Diseases of the digestive system
0.912 0.088 0.000
I50.1 Left ventricular failure
0.911 0.089 0.000
R02 Gangrene, not elsewhere classified
0.909 0.091 0.000
S90-S99 Injuries to the ankle and foot
0.908 0.092 0.000
S80-S89 Injuries to the knee and lower leg
0.908 0.092 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.907 0.093 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.900 0.100 0.000
M80-M85 Disorders of bone density and structure
0.893 0.107 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.893 0.107 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.891 0.109 0.000
R63 Symptoms and signs concerning food and fluid intake
0.887 0.113 0.000
J35 Chronic diseases of tonsils and adenoids
0.883 0.117 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.883 0.117 0.000
F41.9 Anxiety disorder, unspecified
0.882 0.118 0.000
I22 Subsequent myocardial infarction
0.882 0.118 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.882 0.118 0.000
R06.8 Other and unspecified abnormalities of breathing
0.880 0.120 0.000
I33 Acute and subacute endocarditis
0.879 0.121 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.879 0.121 0.000
I49 Other cardiac arrhythmias
0.879 0.121 0.000
I71.0 Dissection of aorta [any part]
0.877 0.123 0.000
I24 Other acute ischaemic heart diseases
0.876 0.124 0.000
T78 Adverse effects, not elsewhere classified
0.873 0.127 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.872 0.128 0.000
R52 Pain, not elsewhere classified
0.870 0.130 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.869 0.131 0.000
M40-M43 Deforming dorsopathies
0.865 0.135 0.000
T92 Sequelae of injuries of upper limb
0.864 0.136 0.000
I51 Complications and ill-defined descriptions of heart disease
0.863 0.137 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.856 0.144 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.854 0.146 0.000
I74 Arterial embolism and thrombosis
0.854 0.146 0.000
E20-E35 Disorders of other endocrine glands
0.852 0.148 0.000
I50.9 Heart failure, unspecified
0.850 0.150 0.000
I42 Cardiomyopathy
0.850 0.150 0.000
M79.7 Fibromyalgia
0.846 0.154 0.000
T42.4 Benzodiazepines
0.846 0.154 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.846 0.154 0.000
M06 Other rheumatoid arthritis
0.844 0.156 0.000
I34 Nonrheumatic mitral valve disorders
0.842 0.158 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.841 0.159 0.000
J43 Emphysema
0.841 0.159 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.841 0.159 0.000
J42 Unspecified chronic bronchitis
0.839 0.161 0.000
K76.6 Portal hypertension
0.837 0.163 0.000
J44 Other chronic obstructive pulmonary disease
0.834 0.166 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.833 0.167 0.000
J30 Vasomotor and allergic rhinitis
0.832 0.168 0.000
R61 Hyperhidrosis
0.829 0.171 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.829 0.171 0.000
E00-E07 Disorders of thyroid gland
0.829 0.171 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.827 0.173 0.000
R50 Fever of unknown origin
0.824 0.176 0.000
Y57 Other and unspecified drugs and medicaments
0.824 0.176 0.000
I25.2 Old myocardial infarction
0.823 0.177 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.822 0.178 0.000
D80-D89 Certain disorders involving the immune mechanism
0.821 0.179 0.000
M91-M94 Chondropathies
0.821 0.179 0.000
R74 Abnormal serum enzyme levels
0.819 0.181 0.000
Chapter VIII Diseases of the ear and mastoid process
0.818 0.182 0.000
S82 Fracture of lower leg, including ankle
0.817 0.183 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.817 0.183 0.000
J35.0 Chronic tonsillitis
0.815 0.185 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.815 0.185 0.000
M79.88 Other specified soft tissue disorders (Other)
0.815 0.185 0.000
I35 Nonrheumatic aortic valve disorders
0.814 0.186 0.000
K76.8 Other specified diseases of liver
0.814 0.186 0.000
S70-S79 Injuries to the hip and thigh
0.811 0.189 0.000
J35.1 Hypertrophy of tonsils
0.811 0.189 0.000
M45-M49 Spondylopathies
0.811 0.189 0.000
R47-R49 Symptoms and signs involving speech and voice
0.810 0.190 0.000
R07 Pain in throat and chest
0.809 0.191 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.807 0.193 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.807 0.193 0.000
T43.2 Other and unspecified antidepressants
0.806 0.194 0.000
J14 Pneumonia due to Haemophilus influenzae
0.806 0.194 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.805 0.195 0.000
R63.4 Abnormal weight loss
0.805 0.195 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.804 0.196 0.000
K75 Other inflammatory liver diseases
0.803 0.197 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.802 0.198 0.000
F41.1 Generalised anxiety disorder
0.801 0.199 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.800 0.200 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.799 0.200 0.000
R06.1 Stridor
0.799 0.201 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.798 0.202 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.798 0.202 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.797 0.203 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.796 0.204 0.000
I24.8 Other forms of acute ischaemic heart disease
0.796 0.204 0.000
I33.0 Acute and subacute infective endocarditis
0.794 0.206 0.000
G30-G32 Other degenerative diseases of the nervous system
0.793 0.206 0.000
R54 Senility
0.792 0.207 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.791 0.209 0.000
K70 Alcoholic liver disease
0.790 0.210 0.000
R06.0 Dyspnoea
0.790 0.210 0.000
I49.0 Ventricular fibrillation and flutter
0.789 0.211 0.000
I34.0 Mitral (valve) insufficiency
0.787 0.213 0.000
J20-J22 Other acute lower respiratory infections
0.787 0.213 0.000
F41.2 Mixed anxiety and depressive disorder
0.785 0.214 0.000
M79.6 Pain in limb
0.784 0.216 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.784 0.216 0.000
S10-S19 Injuries to the neck
0.783 0.217 0.000
E50-E64 Other nutritional deficiencies
0.782 0.218 0.000
J30.1 Allergic rhinitis due to pollen
0.781 0.219 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.781 0.219 0.000
M71 Other bursopathies
0.780 0.220 0.000
K72 Hepatic failure, not elsewhere classified
0.779 0.221 0.000
S92 Fracture of foot, except ankle
0.779 0.221 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.778 0.222 0.000
I51.9 Heart disease, unspecified
0.778 0.222 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.777 0.223 0.000
Y46.2 Hydantoin derivatives
0.777 0.223 0.000
K74 Fibrosis and cirrhosis of liver
0.775 0.225 0.000
I72 Other aneurysm
0.775 0.225 0.000
R52.1 Chronic intractable pain
0.774 0.226 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.774 0.226 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.774 0.226 0.000
M11 Other crystal arthropathies
0.773 0.227 0.000
I60-I69 Cerebrovascular diseases
0.773 0.227 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.772 0.228 0.000
R87 Abnormal findings in specimens from female genital organs
0.771 0.229 0.000
Y60.0 During surgical operation
0.771 0.229 0.000
R52.2 Other chronic pain
0.771 0.229 0.000
I49.5 Sick sinus syndrome
0.771 0.229 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.769 0.231 0.000
E27 Other disorders of adrenal gland
0.768 0.231 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.768 0.232 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.767 0.233 0.000
M14 Arthropathies in other diseases classified elsewhere
0.767 0.233 0.000
M50-M54 Other dorsopathies
0.766 0.234 0.000
J17 Pneumonia in diseases classified elsewhere
0.765 0.235 0.000
R86 Abnormal findings in specimens from male genital organs
0.765 0.235 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.764 0.236 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.762 0.238 0.000
M79.2 Neuralgia and neuritis, unspecified
0.762 0.238 0.000
M84 Disorders of continuity of bone
0.762 0.238 0.000
M15-M19 Arthrosis
0.761 0.239 0.000
M07 Psoriatic and enteropathic arthropathies
0.761 0.239 0.000
S40-S49 Injuries to the shoulder and upper arm
0.761 0.239 0.000
T93 Sequelae of injuries of lower limb
0.761 0.239 0.000
R71 Abnormality of red blood cells
0.760 0.240 0.000
I25.1 Atherosclerotic heart disease
0.760 0.240 0.000
G56 Mononeuropathies of upper limb
0.757 0.243 0.000
I74.5 Embolism and thrombosis of iliac artery
0.756 0.244 0.000
D75 Other diseases of blood and blood-forming organs
0.756 0.244 0.000
Y00-Y09 Assault
0.755 0.245 0.000
G90-G99 Other disorders of the nervous system
0.754 0.246 0.000
I73 Other peripheral vascular diseases
0.752 0.248 0.000
R07.4 Chest pain, unspecified
0.751 0.249 0.000
I05-I09 Chronic rheumatic heart diseases
0.750 0.250 0.000
R58 Haemorrhage, not elsewhere classified
0.750 0.250 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.749 0.251 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.749 0.251 0.000
M41 Scoliosis
0.748 0.252 0.000
J43.9 Emphysema, unspecified
0.748 0.252 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.747 0.252 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.747 0.253 0.000
E40-E46 Malnutrition
0.747 0.253 0.000
J00-J06 Acute upper respiratory infections
0.747 0.253 0.000
J39 Other diseases of upper respiratory tract
0.745 0.255 0.000
D60-D64 Aplastic and other anaemias
0.744 0.256 0.000
X60-X84 Intentional self-harm
0.743 0.256 0.000
T78.4 Allergy, unspecified
0.743 0.257 0.000
V40-V49 Car occupant injured in transport accident
0.742 0.257 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.742 0.258 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.742 0.258 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.741 0.259 0.000
Y84.2 Radiological procedure and radiotherapy
0.741 0.259 0.000
F40 Phobic anxiety disorders
0.740 0.260 0.000
R94.4 Abnormal results of kidney function studies
0.740 0.260 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.740 0.260 0.000
E10-E14 Diabetes mellitus
0.739 0.261 0.000
J18.9 Pneumonia, unspecified
0.738 0.262 0.000
Y44 Agents primarily affecting blood constituents
0.736 0.264 0.000
K50-K52 Noninfective enteritis and colitis
0.736 0.264 0.000
K73 Chronic hepatitis, not elsewhere classified
0.736 0.264 0.000
T98 Sequelae of other and unspecified effects of external causes
0.735 0.265 0.000
J32 Chronic sinusitis
0.734 0.266 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.733 0.267 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.732 0.268 0.000
M60-M63 Disorders of muscles
0.732 0.268 0.000
X20-X29 Contact with venomous animals and plants
0.731 0.268 0.000
R61.9 Hyperhidrosis, unspecified
0.731 0.269 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.730 0.269 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.730 0.270 0.000
S91 Open wound of ankle and foot
0.729 0.271 0.000
Q80-Q89 Other congenital malformations
0.729 0.271 0.000
E88 Other metabolic disorders
0.728 0.272 0.000
I30 Acute pericarditis
0.728 0.272 0.000
G56.0 Carpal tunnel syndrome
0.727 0.273 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.727 0.273 0.000
S82.3 Fracture of lower end of tibia
0.726 0.274 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.726 0.274 0.000
M79.5 Residual foreign body in soft tissue
0.725 0.275 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.725 0.275 0.000
E03 Other hypothyroidism
0.723 0.277 0.000
M76 Enthesopathies of lower limb, excluding foot
0.722 0.278 0.000
M79.64 Pain in limb (Hand)
0.722 0.278 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.722 0.278 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.721 0.279 0.000
M65-M68 Disorders of synovium and tendon
0.721 0.279 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.720 0.280 0.000
R68 Other general symptoms and signs
0.720 0.280 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.720 0.280 0.000
J10 Influenza due to identified influenza virus
0.719 0.281 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.719 0.281 0.000
D73 Diseases of spleen
0.718 0.282 0.000
I20.1 Angina pectoris with documented spasm
0.718 0.282 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.718 0.282 0.000
S86 Injury of muscle and tendon at lower leg level
0.718 0.282 0.000
F80-F89 Disorders of psychological development
0.717 0.283 0.000
J60-J70 Lung diseases due to external agents
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.717 0.283 0.000
J12 Viral pneumonia, not elsewhere classified
0.717 0.283 0.000
J09 Influenza due to certain identified influenza virus
0.717 0.283 0.000
J18.8 Other pneumonia, organism unspecified
0.717 0.283 0.000
J18.2 Hypostatic pneumonia, unspecified
0.717 0.283 0.000
I49.9 Cardiac arrhythmia, unspecified
0.717 0.283 0.000
S82.4 Fracture of fibula alone
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.715 0.285 0.000
M10.96 Gout, unspecified (Lower leg)
0.713 0.286 0.000
D86 Sarcoidosis
0.713 0.287 0.000
Y43 Primarily systemic agents
0.713 0.287 0.000
I42.2 Other hypertrophic cardiomyopathy
0.712 0.288 0.000
I35.1 Aortic (valve) insufficiency
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
Y57.5 X-ray contrast media
0.709 0.291 0.000
M19 Other arthrosis
0.709 0.291 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.708 0.292 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.708 0.292 0.000
K76.7 Hepatorenal syndrome
0.707 0.292 0.000
M12 Other specific arthropathies
0.707 0.293 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.707 0.293 0.000
M08 Juvenile arthritis
0.707 0.293 0.000
M79.9 Soft tissue disorder, unspecified
0.706 0.294 0.000
M79.3 Panniculitis, unspecified
0.706 0.294 0.000
J15.4 Pneumonia due to other streptococci
0.706 0.294 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.705 0.294 0.000
R94.7 Abnormal results of other endocrine function studies
0.705 0.294 0.000
R94.6 Abnormal results of thyroid function studies
0.705 0.294 0.000
R94.2 Abnormal results of pulmonary function studies
0.705 0.294 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.705 0.294 0.000
R94.0 Abnormal results of function studies of central nervous system
0.705 0.294 0.000
F48 Other neurotic disorders
0.705 0.295 0.000
F44 Dissociative [conversion] disorders
0.705 0.295 0.000
I46 Cardiac arrest
0.705 0.295 0.000
M54 Dorsalgia
0.705 0.295 0.000
M06.9 Rheumatoid arthritis, unspecified
0.704 0.296 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.704 0.296 0.000
R77 Other abnormalities of plasma proteins
0.704 0.296 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.704 0.296 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.704 0.296 0.000
R74.8 Abnormal levels of other serum enzymes
0.703 0.297 0.000
F60-F69 Disorders of adult personality and behaviour
0.703 0.297 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.703 0.297 0.000
M06.3 Rheumatoid nodule
0.702 0.298 0.000
D72 Other disorders of white blood cells
0.702 0.298 0.000
F41.8 Other specified anxiety disorders
0.701 0.299 0.000
F41.3 Other mixed anxiety disorders
0.701 0.299 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.701 0.299 0.000
E78.6 Lipoprotein deficiency
0.701 0.299 0.000
E78.4 Other hyperlipidaemia
0.701 0.299 0.000
E78.3 Hyperchylomicronaemia
0.701 0.299 0.000
E78.1 Pure hyperglyceridaemia
0.701 0.299 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.701 0.299 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.701 0.299 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.701 0.299 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.701 0.299 0.000
M86-M90 Other osteopathies
0.700 0.300 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.700 0.300 0.000
E85 Amyloidosis
0.700 0.300 0.000
E84 Cystic fibrosis
0.700 0.300 0.000
E79 Disorders of purine and pyrimidine metabolism
0.700 0.300 0.000
E77 Disorders of glycoprotein metabolism
0.700 0.300 0.000
E76 Disorders of glycosaminoglycan metabolism
0.700 0.300 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.700 0.300 0.000
E74 Other disorders of carbohydrate metabolism
0.700 0.300 0.000
E73 Lactose intolerance
0.700 0.300 0.000
E72 Other disorders of amino-acid metabolism
0.700 0.300 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.700 0.300 0.000
E70 Disorders of aromatic amino-acid metabolism
0.700 0.300 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.700 0.300 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.700 0.300 0.000
Y40 Systemic antibiotics
0.699 0.301 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.699 0.301 0.000
E27.1 Primary adrenocortical insufficiency
0.699 0.301 0.000
H80-H83 Diseases of inner ear
0.698 0.302 0.000
S82.5 Fracture of medial malleolus
0.698 0.302 0.000
Chapter XXII Codes for special purposes
0.697 0.303 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.697 0.303 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.696 0.304 0.000
J41 Simple and mucopurulent chronic bronchitis
0.696 0.304 0.000
M79.70 Fibromyalgia (Multiple sites)
0.696 0.304 0.000
I85 Oesophageal varices
0.695 0.305 0.000
M79.1 Myalgia
0.695 0.305 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.694 0.306 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.694 0.306 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.694 0.306 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.694 0.306 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.694 0.306 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.694 0.306 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.694 0.306 0.000
F11 Mental and behavioural disorders due to use of opioids
0.694 0.306 0.000
D75.2 Essential thrombocytosis
0.694 0.306 0.000
R40 Somnolence, stupor and coma
0.693 0.307 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.693 0.307 0.000
R62 Lack of expected normal physiological development
0.693 0.307 0.000
R64 Cachexia
0.693 0.307 0.000
M82 Osteoporosis in diseases classified elsewhere
0.693 0.307 0.000
I51.6 Cardiovascular disease, unspecified
0.693 0.307 0.000
Y59 Other and unspecified vaccines and biological substances
0.693 0.307 0.000
Y58 Bacterial vaccines
0.693 0.307 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.693 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.693 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.693 0.307 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.693 0.307 0.000
Y48 Anaesthetics and therapeutic gases
0.693 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.693 0.307 0.000
I20.9 Angina pectoris, unspecified
0.693 0.307 0.000
T45.0 Antiallergic and antiemetic drugs
0.692 0.307 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.692 0.308 0.000
G70-G73 Diseases of myoneural junction and muscle
0.692 0.308 0.000
K35-K38 Diseases of appendix
0.692 0.308 0.000
Y52 Agents primarily affecting the cardiovascular system
0.691 0.309 0.000
M10.4 Other secondary gout
0.691 0.309 0.000
M10.3 Gout due to impairment of renal function
0.691 0.309 0.000
M10.2 Drug-induced gout
0.691 0.309 0.000
M10.1 Lead-induced gout
0.691 0.309 0.000
M10.0 Idiopathic gout
0.691 0.309 0.000
I42.6 Alcoholic cardiomyopathy
0.691 0.309 0.000
E10 Insulin-dependent diabetes mellitus
0.691 0.309 0.000
I61 Intracerebral haemorrhage
0.690 0.310 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.690 0.310 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.689 0.311 0.000
J11 Influenza, virus not identified
0.688 0.312 0.000
M79.79 Fibromyalgia (Site unspecified)
0.688 0.312 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.687 0.313 0.000
Y42.7 Androgens and anabolic congeners
0.687 0.313 0.000
S90 Superficial injury of ankle and foot
0.687 0.313 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.687 0.313 0.000
D55-D59 Haemolytic anaemias
0.686 0.314 0.000
F17.9 Unspecified mental and behavioural disorder
0.686 0.314 0.000
F17.8 Other mental and behavioural disorders
0.686 0.314 0.000
F17.7 Residual and late-onset psychotic disorder
0.686 0.314 0.000
F17.6 Amnesic syndrome
0.686 0.314 0.000
F17.5 Psychotic disorder
0.686 0.314 0.000
F17.4 Withdrawal state with delirium
0.686 0.314 0.000
F17.3 Withdrawal state
0.686 0.314 0.000
F17.0 Acute intoxication
0.686 0.314 0.000
I25.6 Silent myocardial ischaemia
0.685 0.315 0.000
I25.4 Coronary artery aneurysm
0.685 0.315 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.685 0.315 0.000
I25.3 Aneurysm of heart
0.685 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.685 0.315 0.000
I78.9 Disease of capillaries, unspecified
0.685 0.315 0.000
I78.8 Other diseases of capillaries
0.685 0.315 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.685 0.315 0.000
R49 Voice disturbances
0.685 0.315 0.000
I36 Nonrheumatic tricuspid valve disorders
0.684 0.316 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.683 0.317 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.682 0.318 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
I47.0 Reentry ventricular arrhythmia
0.681 0.319 0.000
G51 Facial nerve disorders
0.681 0.319 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.680 0.320 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.680 0.320 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.680 0.320 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.680 0.320 0.000
M80 Osteoporosis with pathological fracture
0.680 0.320 0.000
I10-I15 Hypertensive diseases
0.680 0.320 0.000
R06.4 Hyperventilation
0.680 0.320 0.000
M10.98 Gout, unspecified (Other)
0.679 0.320 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.679 0.320 0.000
M10.94 Gout, unspecified (Hand)
0.679 0.320 0.000
M10.93 Gout, unspecified (Forearm)
0.679 0.320 0.000
M10.92 Gout, unspecified (Upper arm)
0.679 0.320 0.000
M10.91 Gout, unspecified (Shoulder region)
0.679 0.320 0.000
M10.90 Gout, unspecified (Multiple sites)
0.679 0.320 0.000
R87.6 Abnormal cytological findings
0.679 0.321 0.000
I38 Endocarditis, valve unspecified
0.677 0.322 0.000
T43.9 Psychotropic drug, unspecified
0.677 0.323 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.677 0.323 0.000
T43.6 Psychostimulants with abuse potential
0.677 0.323 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.677 0.323 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.677 0.323 0.000
F45 Somatoform disorders
0.677 0.323 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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