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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10774625
log Bayes Factor = 134.733
Chromosome 12   position 111,910,219  (GRCh37) Explore rs10774625 on Ensembl!
Variant rs10774625 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
1.000 0.000 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
C77.3 Axillary and upper limb lymph nodes
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
M06.9 Rheumatoid arthritis, unspecified
0.998 0.002 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.002 0.998
Z95.2 Presence of prosthetic heart valve
0.998 0.002 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.998 0.002 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.997 0.003 0.000
E05.9 Thyrotoxicosis, unspecified
0.997 0.003 0.000
G81 Hemiplegia
0.996 0.004 0.000
M06 Other rheumatoid arthritis
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.005 0.995
D55-D59 Haemolytic anaemias
0.995 0.005 0.000
G81.9 Hemiplegia, unspecified
0.995 0.005 0.000
M05-M14 Inflammatory polyarthropathies
0.994 0.006 0.000
I21.9 Acute myocardial infarction, unspecified
0.993 0.007 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.992 0.008 0.000
Z95.4 Presence of other heart-valve replacement
0.991 0.009 0.000
I22 Subsequent myocardial infarction
0.991 0.009 0.000
G20-G26 Extrapyramidal and movement disorders
0.990 0.010 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.990 0.010 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.985 0.015 0.000
E27 Other disorders of adrenal gland
0.984 0.016 0.000
D75 Other diseases of blood and blood-forming organs
0.984 0.016 0.000
C79 Secondary malignant neoplasm of other sites
0.000 0.017 0.983
G24 Dystonia
0.982 0.018 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.982 0.018 0.000
I74 Arterial embolism and thrombosis
0.981 0.019 0.000
E06 Thyroiditis
0.979 0.021 0.000
M05 Seropositive rheumatoid arthritis
0.979 0.021 0.000
D59 Acquired haemolytic anaemia
0.974 0.026 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.972 0.028 0.000
E10.5 With peripheral circulatory complications
0.972 0.028 0.000
D75.1 Secondary polycythaemia
0.972 0.028 0.000
E10.9 Without complications
0.970 0.030 0.000
E23 Hypofunction and other disorders of pituitary gland
0.970 0.030 0.000
I25.5 Ischaemic cardiomyopathy
0.968 0.032 0.000
E27.1 Primary adrenocortical insufficiency
0.967 0.033 0.000
G24.9 Dystonia, unspecified
0.967 0.033 0.000
C50 Malignant neoplasm of breast
0.000 0.033 0.967
M05.9 Seropositive rheumatoid arthritis, unspecified
0.963 0.037 0.000
C50.9 Breast, unspecified
0.000 0.038 0.962
E10.1 With ketoacidosis
0.954 0.046 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.953 0.047 0.000
M07 Psoriatic and enteropathic arthropathies
0.951 0.049 0.000
D59.1 Other autoimmune haemolytic anaemias
0.949 0.051 0.000
E06.3 Autoimmune thyroiditis
0.948 0.052 0.000
G83 Other paralytic syndromes
0.944 0.056 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.000 0.056 0.944
C50.4 Upper-outer quadrant of breast
0.000 0.056 0.944
D75.2 Essential thrombocytosis
0.942 0.058 0.000
E10.4 With neurological complications
0.941 0.059 0.000
I73 Other peripheral vascular diseases
0.940 0.060 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.060 0.940
E10.3 With ophthalmic complications
0.936 0.064 0.000
C50.8 Overlapping lesion of breast
0.000 0.067 0.933
Z95.8 Presence of other cardiac and vascular implants and grafts
0.932 0.068 0.000
C78.7 Secondary malignant neoplasm of liver
0.000 0.070 0.930
G70-G73 Diseases of myoneural junction and muscle
0.928 0.072 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.928 0.072 0.000
I73.9 Peripheral vascular disease, unspecified
0.925 0.075 0.000
K90 Intestinal malabsorption
0.924 0.076 0.000
I74.5 Embolism and thrombosis of iliac artery
0.923 0.077 0.000
M07.3 Other psoriatic arthropathies
0.923 0.077 0.000
D60-D64 Aplastic and other anaemias
0.921 0.079 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.920 0.080 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.918 0.082 0.000
G80 Infantile cerebral palsy
0.912 0.088 0.000
C77.9 Lymph node, unspecified
0.000 0.089 0.911
G25 Other extrapyramidal and movement disorders
0.909 0.091 0.000
E10.0 With coma
0.907 0.093 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.906 0.094 0.000
E50-E64 Other nutritional deficiencies
0.905 0.095 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.904 0.096 0.000
I23 Certain current complications following acute myocardial infarction
0.903 0.097 0.000
C50.1 Central portion of breast
0.000 0.098 0.902
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.901 0.099 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.899 0.101 0.000
K74 Fibrosis and cirrhosis of liver
0.898 0.102 0.000
E10.2 With renal complications
0.898 0.102 0.000
K90-K93 Other diseases of the digestive system
0.897 0.103 0.000
K70-K77 Diseases of liver
0.897 0.103 0.000
Chapter XI Diseases of the digestive system
0.896 0.104 0.000
E23.6 Other disorders of pituitary gland
0.896 0.104 0.000
E23.2 Diabetes insipidus
0.895 0.105 0.000
K74.3 Primary biliary cirrhosis
0.894 0.106 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.893 0.107 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.893 0.107 0.000
D58 Other hereditary haemolytic anaemias
0.893 0.107 0.000
C50.0 Nipple and areola
0.000 0.108 0.892
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.108 0.892
I77 Other disorders of arteries and arterioles
0.891 0.109 0.000
G83.4 Cauda equina syndrome
0.888 0.112 0.000
I25.3 Aneurysm of heart
0.888 0.112 0.000
M06.4 Inflammatory polyarthropathy
0.884 0.116 0.000
E20 Hypoparathyroidism
0.883 0.117 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.877 0.123 0.000
D56 Thalassaemia
0.875 0.125 0.000
E22 Hyperfunction of pituitary gland
0.875 0.125 0.000
E07 Other disorders of thyroid
0.867 0.133 0.000
E28 Ovarian dysfunction
0.866 0.134 0.000
I21.4 Acute subendocardial myocardial infarction
0.866 0.134 0.000
C78.2 Secondary malignant neoplasm of pleura
0.000 0.137 0.863
K73 Chronic hepatitis, not elsewhere classified
0.860 0.140 0.000
G24.5 Blepharospasm
0.859 0.141 0.000
C77.8 Lymph nodes of multiple regions
0.000 0.142 0.858
C50-C50 Malignant neoplasm of breast
0.000 0.148 0.852
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.148 0.852
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.850 0.150 0.000
G80.9 Infantile cerebral palsy, unspecified
0.843 0.157 0.000
E06.9 Thyroiditis, unspecified
0.843 0.157 0.000
I05-I09 Chronic rheumatic heart diseases
0.842 0.158 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.161 0.839
I21.3 Acute transmural myocardial infarction of unspecified site
0.838 0.162 0.000
I77.6 Arteritis, unspecified
0.835 0.165 0.000
E27.2 Addisonian crisis
0.835 0.165 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.830 0.170 0.000
D69 Purpura and other haemorrhagic conditions
0.828 0.172 0.000
M08 Juvenile arthritis
0.824 0.176 0.000
G71 Primary disorders of muscles
0.823 0.177 0.000
C77.2 Intra-abdominal lymph nodes
0.000 0.178 0.822
D75.8 Other specified diseases of blood and blood-forming organs
0.819 0.181 0.000
I23.8 Other current complications following acute myocardial infarction
0.818 0.182 0.000
G25.0 Essential tremor
0.818 0.182 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.818 0.182 0.000
C50.2 Upper-inner quadrant of breast
0.000 0.184 0.816
E27.8 Other specified disorders of adrenal gland
0.812 0.188 0.000
E34 Other endocrine disorders
0.811 0.189 0.000
E23.0 Hypopituitarism
0.809 0.191 0.000
E03.8 Other specified hypothyroidism
0.809 0.191 0.000
I77.1 Stricture of artery
0.807 0.193 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.807 0.193 0.000
M05.1 Rheumatoid lung disease
0.805 0.195 0.000
I12 Hypertensive renal disease
0.805 0.195 0.000
E21.3 Hyperparathyroidism, unspecified
0.805 0.195 0.000
K75 Other inflammatory liver diseases
0.805 0.195 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.804 0.196 0.000
D58.9 Hereditary haemolytic anaemia, unspecified
0.800 0.200 0.000
K74.0 Hepatic fibrosis
0.799 0.201 0.000
E07.9 Disorder of thyroid, unspecified
0.799 0.201 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.203 0.797
K73.2 Chronic active hepatitis, not elsewhere classified
0.796 0.204 0.000
G72 Other myopathies
0.793 0.207 0.000
E31 Polyglandular dysfunction
0.793 0.207 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.208 0.792
E58 Dietary calcium deficiency
0.790 0.210 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.788 0.212 0.000
G83.9 Paralytic syndrome, unspecified
0.786 0.214 0.000
I22.8 Subsequent myocardial infarction of other sites
0.785 0.215 0.000
C77.4 Inguinal and lower limb lymph nodes
0.000 0.217 0.783
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.782 0.218 0.000
M12 Other specific arthropathies
0.777 0.223 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.775 0.225 0.000
E21.0 Primary hyperparathyroidism
0.774 0.226 0.000
D56.3 Thalassaemia trait
0.774 0.226 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.774 0.226 0.000
C79.2 Secondary malignant neoplasm of skin
0.000 0.227 0.773
D59.9 Acquired haemolytic anaemia, unspecified
0.773 0.227 0.000
E22.1 Hyperprolactinaemia
0.772 0.228 0.000
K74.5 Biliary cirrhosis, unspecified
0.772 0.228 0.000
Chapter II Neoplasms
0.000 0.230 0.770
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.770 0.230 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.769 0.231 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.768 0.232 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.000 0.234 0.766
I25.6 Silent myocardial ischaemia
0.764 0.236 0.000
E03.1 Congenital hypothyroidism without goitre
0.762 0.238 0.000
E20.9 Hypoparathyroidism, unspecified
0.761 0.239 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.759 0.241 0.000
G21 Secondary Parkinsonism
0.756 0.244 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.755 0.244 0.000
M10 Gout
0.754 0.246 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.753 0.246 0.000
I13 Hypertensive heart and renal disease
0.753 0.247 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.752 0.248 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.000 0.248 0.752
E40-E46 Malnutrition
0.752 0.248 0.000
E28.3 Primary ovarian failure
0.752 0.248 0.000
L40 Psoriasis
0.752 0.248 0.000
L40.5 Arthropathic psoriasis
0.750 0.250 0.000
G24.1 Idiopathic familial dystonia
0.750 0.250 0.000
G25.2 Other specified forms of tremor
0.750 0.250 0.000
L40-L45 Papulosquamous disorders
0.749 0.251 0.000
E06.1 Subacute thyroiditis
0.747 0.253 0.000
I07 Rheumatic tricuspid valve diseases
0.746 0.253 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.254 0.746
Chapter XII Diseases of the skin and subcutaneous tissue
0.743 0.257 0.000
D69.4 Other primary thrombocytopenia
0.742 0.258 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.742 0.258 0.000
M00-M03 Infectious arthropathies
0.739 0.261 0.000
M05.0 Felty's syndrome
0.738 0.262 0.000
I15 Secondary hypertension
0.736 0.264 0.000
I25.4 Coronary artery aneurysm
0.736 0.264 0.000
G83.1 Monoplegia of lower limb
0.734 0.266 0.000
G80.2 Infantile hemiplegia
0.734 0.266 0.000
E10.8 With unspecified complications
0.732 0.267 0.000
I60-I69 Cerebrovascular diseases
0.730 0.270 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.729 0.271 0.000
M06.8 Other specified rheumatoid arthritis
0.728 0.271 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.727 0.273 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.726 0.274 0.000
G71.1 Myotonic disorders
0.723 0.277 0.000
I63 Cerebral infarction
0.723 0.277 0.000
D73 Diseases of spleen
0.722 0.278 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.721 0.279 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.721 0.279 0.000
K75.4 Autoimmune hepatitis
0.720 0.280 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.716 0.284 0.000
E05.5 Thyroid crisis or storm
0.715 0.285 0.000
E05.4 Thyrotoxicosis factitia
0.715 0.285 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.715 0.285 0.000
G25.3 Myoclonus
0.715 0.285 0.000
G81.0 Flaccid hemiplegia
0.714 0.286 0.000
M06.2 Rheumatoid bursitis
0.714 0.286 0.000
M06.1 Adult-onset Still's disease
0.714 0.286 0.000
D55 Anaemia due to enzyme disorders
0.713 0.287 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.713 0.287 0.000
E14 Unspecified diabetes mellitus
0.713 0.287 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.000 0.288 0.712
G24.8 Other dystonia
0.711 0.289 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.710 0.290 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.290 0.710
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.710 0.290 0.000
G22 Parkinsonism in diseases classified elsewhere
0.710 0.290 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.709 0.291 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.709 0.291 0.000
E25 Adrenogenital disorders
0.709 0.291 0.000
M05.8 Other seropositive rheumatoid arthritis
0.708 0.292 0.000
K73.9 Chronic hepatitis, unspecified
0.706 0.294 0.000
D74 Methaemoglobinaemia
0.706 0.294 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.706 0.294 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.706 0.294 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.706 0.294 0.000
E53 Deficiency of other B group vitamins
0.706 0.294 0.000
E27.5 Adrenomedullary hyperfunction
0.706 0.294 0.000
E27.0 Other adrenocortical overactivity
0.706 0.294 0.000
G24.3 Spasmodic torticollis
0.705 0.294 0.000
D57 Sickle-cell disorders
0.705 0.295 0.000
G24.4 Idiopathic orofacial dystonia
0.704 0.296 0.000
G24.2 Idiopathic nonfamilial dystonia
0.704 0.296 0.000
E06.4 Drug-induced thyroiditis
0.702 0.298 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.702 0.298 0.000
E06.0 Acute thyroiditis
0.702 0.298 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.702 0.298 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.702 0.298 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.701 0.299 0.000
E61 Deficiency of other nutrient elements
0.698 0.302 0.000
D59.8 Other acquired haemolytic anaemias
0.698 0.302 0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.698 0.302 0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.698 0.302 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.698 0.302 0.000
D59.3 Haemolytic-uraemic syndrome
0.698 0.302 0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.698 0.302 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.698 0.302 0.000
G23 Other degenerative diseases of basal ganglia
0.697 0.303 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.697 0.303 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.696 0.304 0.000
E23.1 Drug-induced hypopituitarism
0.696 0.304 0.000
G24.0 Drug-induced dystonia
0.694 0.306 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.694 0.306 0.000
G72.9 Myopathy, unspecified
0.693 0.307 0.000
I05 Rheumatic mitral valve diseases
0.693 0.307 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.690 0.310 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.690 0.310 0.000
G25.1 Drug-induced tremor
0.689 0.310 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.311 0.689
Z95.3 Presence of xenogenic heart valve
0.689 0.311 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.313 0.687
I73.1 Thromboangiitis obliterans [Buerger]
0.687 0.313 0.000
G70 Myasthenia gravis and other myoneural disorders
0.686 0.314 0.000
G81.1 Spastic hemiplegia
0.686 0.314 0.000
M10.0 Idiopathic gout
0.686 0.314 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.685 0.315 0.000
E10.6 With other specified complications
0.684 0.316 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.317 0.683
Chapter XXII Codes for special purposes
0.682 0.318 0.000
M07.5 Arthropathy in ulcerative colitis
0.682 0.318 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.682 0.318 0.000
M07.2 Psoriatic spondylitis
0.682 0.318 0.000
M07.1 Arthritis mutilans
0.682 0.318 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.682 0.318 0.000
D58.0 Hereditary spherocytosis
0.681 0.319 0.000
E26 Hyperaldosteronism
0.680 0.320 0.000
I07.1 Tricuspid insufficiency
0.678 0.322 0.000
G83.5 Locked-in syndrome
0.677 0.323 0.000
G83.3 Monoplegia, unspecified
0.677 0.323 0.000
G83.0 Diplegia of upper limbs
0.677 0.323 0.000
E20.8 Other hypoparathyroidism
0.676 0.323 0.000
E20.1 Pseudohypoparathyroidism
0.676 0.324 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.676 0.324 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.676 0.324 0.000
E55 Vitamin D deficiency
0.675 0.325 0.000
E51 Thiamine deficiency
0.673 0.327 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.673 0.327 0.000
E34.0 Carcinoid syndrome
0.672 0.328 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.672 0.328 0.000
L40.9 Psoriasis, unspecified
0.671 0.329 0.000
M08.0 Juvenile rheumatoid arthritis
0.669 0.330 0.000
I00-I02 Acute rheumatic fever
0.667 0.333 0.000
I77.2 Rupture of artery
0.666 0.334 0.000
I06 Rheumatic aortic valve diseases
0.666 0.334 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.666 0.334 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.666 0.334 0.000
D56.1 Beta thalassaemia
0.664 0.336 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.664 0.336 0.000
K90.3 Pancreatic steatorrhoea
0.662 0.338 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.662 0.338 0.000
K90.1 Tropical sprue
0.662 0.338 0.000
G80.0 Spastic cerebral palsy
0.662 0.338 0.000
E06.5 Other chronic thyroiditis
0.662 0.338 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.661 0.338 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.661 0.338 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.661 0.339 0.000
I12.9 Hypertensive renal disease without renal failure
0.660 0.340 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.660 0.340 0.000
E28.2 Polycystic ovarian syndrome
0.660 0.340 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.658 0.342 0.000
K77 Liver disorders in diseases classified elsewhere
0.656 0.343 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.656 0.344 0.000
M07.6 Other enteropathic arthropathies
0.655 0.345 0.000
D58.2 Other haemoglobinopathies
0.654 0.346 0.000
G80.4 Ataxic cerebral palsy
0.654 0.346 0.000
G80.3 Dyskinetic cerebral palsy
0.654 0.346 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.652 0.348 0.000
G25.5 Other chorea
0.652 0.348 0.000
G25.4 Drug-induced chorea
0.652 0.348 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.651 0.349 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.649 0.350 0.000
M06.3 Rheumatoid nodule
0.649 0.350 0.000
D75.0 Familial erythrocytosis
0.649 0.350 0.000
D63.1 Anaemia in other chronic diseases classified elsewhere
0.649 0.351 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.649 0.351 0.000
E63 Other nutritional deficiencies
0.649 0.351 0.000
E50 Vitamin A deficiency
0.649 0.351 0.000
E60 Dietary zinc deficiency
0.649 0.351 0.000
E59 Dietary selenium deficiency
0.649 0.351 0.000
E54 Ascorbic acid deficiency
0.649 0.351 0.000
E52 Niacin deficiency [pellagra]
0.649 0.351 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.648 0.351 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.648 0.352 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.648 0.352 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.648 0.352 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.648 0.352 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.648 0.352 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.648 0.352 0.000
E31.0 Autoimmune polyglandular failure
0.645 0.355 0.000
K74.4 Secondary biliary cirrhosis
0.644 0.356 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.644 0.356 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.643 0.357 0.000
M12.2 Villonodular synovitis (pigmented)
0.642 0.358 0.000
I72 Other aneurysm
0.641 0.359 0.000
M08.9 Juvenile arthritis, unspecified
0.641 0.359 0.000
I77.0 Arteriovenous fistula, acquired
0.641 0.359 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.640 0.360 0.000
D58.1 Hereditary elliptocytosis
0.640 0.360 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.361 0.639
I77.5 Necrosis of artery
0.639 0.361 0.000
I77.4 Coeliac artery compression syndrome
0.639 0.361 0.000
C76.0 Head, face and neck
0.000 0.361 0.639
M05.10 Rheumatoid lung disease (Multiple sites)
0.639 0.361 0.000
K71 Toxic liver disease
0.638 0.362 0.000
E21.2 Other hyperparathyroidism
0.637 0.363 0.000
G72.8 Other specified myopathies
0.637 0.363 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.637 0.363 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.636 0.364 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.636 0.364 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.635 0.365 0.000
L10-L14 Bullous disorders
0.635 0.365 0.000
M00 Pyogenic arthritis
0.634 0.366 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.634 0.366 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.634 0.366 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.634 0.366 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.634 0.366 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.634 0.366 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.634 0.366 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.634 0.366 0.000
E20.0 Idiopathic hypoparathyroidism
0.633 0.367 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.631 0.369 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.631 0.369 0.000
G83.2 Monoplegia of upper limb
0.630 0.370 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.630 0.370 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.000 0.371 0.629
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.628 0.372 0.000
D56.9 Thalassaemia, unspecified
0.627 0.373 0.000
D56.8 Other thalassaemias
0.627 0.373 0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.627 0.373 0.000
D56.2 Delta-beta thalassaemia
0.627 0.373 0.000
D56.0 Alpha thalassaemia
0.627 0.373 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.627 0.373 0.000
E22.8 Other hyperfunction of pituitary gland
0.627 0.373 0.000
M07.38 Other psoriatic arthropathies (Other)
0.627 0.373 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.627 0.373 0.000
M11 Other crystal arthropathies
0.626 0.374 0.000
E05.8 Other thyrotoxicosis
0.625 0.374 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.375 0.625
M05.2 Rheumatoid vasculitis
0.623 0.376 0.000
E07.1 Dyshormogenetic goitre
0.622 0.378 0.000
E07.0 Hypersecretion of calcitonin
0.622 0.378 0.000
E28.9 Ovarian dysfunction, unspecified
0.621 0.379 0.000
E28.8 Other ovarian dysfunction
0.621 0.379 0.000
E28.1 Androgen excess
0.621 0.379 0.000
E28.0 Oestrogen excess
0.621 0.379 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.620 0.380 0.000
I20.1 Angina pectoris with documented spasm
0.620 0.380 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.381 0.619
E14.3 With ophthalmic complications
0.618 0.382 0.000
D73.3 Abscess of spleen
0.617 0.383 0.000
C84.0 Mycosis fungoides
0.000 0.383 0.617
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.616 0.384 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.616 0.384 0.000
E10.7 With multiple complications
0.615 0.384 0.000
C76.1 Thorax
0.000 0.384 0.615
C77.1 Intrathoracic lymph nodes
0.000 0.384 0.616
G80.8 Other infantile cerebral palsy
0.615 0.385 0.000
E21.4 Other specified disorders of parathyroid gland
0.613 0.387 0.000
I05.0 Mitral stenosis
0.612 0.388 0.000
G03 Meningitis due to other and unspecified causes
0.611 0.389 0.000
K90.8 Other intestinal malabsorption
0.610 0.390 0.000
G83.8 Other specified paralytic syndromes
0.609 0.391 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.608 0.392 0.000
G80.1 Spastic diplegia
0.606 0.393 0.000
G71.0 Muscular dystrophy
0.606 0.394 0.000
K74.1 Hepatic sclerosis
0.606 0.394 0.000
E56 Other vitamin deficiencies
0.605 0.394 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.395 0.605
I77.3 Arterial fibromuscular dysplasia
0.604 0.396 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.604 0.396 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.604 0.396 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.601 0.399 0.000
G36 Other acute disseminated demyelination
0.600 0.400 0.000
I65.2 Occlusion and stenosis of carotid artery
0.598 0.402 0.000
E34.3 Short stature, not elsewhere classified
0.598 0.402 0.000
E34.9 Endocrine disorder, unspecified
0.598 0.402 0.000
I20.8 Other forms of angina pectoris
0.598 0.402 0.000
K74.6 Other and unspecified cirrhosis of liver
0.598 0.402 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.597 0.403 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.596 0.403 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.596 0.404 0.000
C80 Malignant neoplasm without specification of site
0.000 0.405 0.595
T82.1 Mechanical complication of cardiac electronic device
0.595 0.405 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.593 0.407 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.592 0.408 0.000
M08.8 Other juvenile arthritis
0.591 0.409 0.000
M08.4 Pauciarticular juvenile arthritis
0.591 0.409 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.591 0.409 0.000
M08.2 Juvenile arthritis with systemic onset
0.591 0.409 0.000
M08.1 Juvenile ankylosing spondylitis
0.591 0.409 0.000
G71.9 Primary disorder of muscle, unspecified
0.590 0.409 0.000
G71.8 Other primary disorders of muscles
0.590 0.409 0.000
G71.2 Congenital myopathies
0.590 0.409 0.000
L42 Pityriasis rosea
0.590 0.409 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.590 0.410 0.000
I72.4 Aneurysm of artery of lower extremity
0.589 0.411 0.000
C79.6 Secondary malignant neoplasm of ovary
0.000 0.411 0.589
M65-M68 Disorders of synovium and tendon
0.589 0.411 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.588 0.412 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.588 0.412 0.000
L43 Lichen planus
0.588 0.412 0.000
D69.8 Other specified haemorrhagic conditions
0.588 0.412 0.000
I12.0 Hypertensive renal disease with renal failure
0.586 0.414 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.584 0.416 0.000
I99 Other and unspecified disorders of circulatory system
0.584 0.416 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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