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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0250
log Bayes Factor = 43.399
contains 4 variants:
rs10490871
lBF = 6.364
Chr 3 : 35,667,761
rs77170649
lBF = 7.494
Chr 6 : 135,010,546
rs1860374
lBF = 6.157
Chr17 : 59,277,614
rs34484155
lBF = 9.504
Chr21 : 30,598,750
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I50.1 Left ventricular failure
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
I51 Complications and ill-defined descriptions of heart disease
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I50.0 Congestive heart failure
1.000 0.000 0.000
I51.7 Cardiomegaly
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I08 Multiple valve diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I05-I09 Chronic rheumatic heart diseases
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I35 Nonrheumatic aortic valve disorders
1.000 0.000 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.999 0.001 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.999 0.001 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.999 0.001 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.999 0.001 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.998 0.002 0.000
Chapter VIII Diseases of the ear and mastoid process
0.998 0.002 0.000
H65-H75 Diseases of middle ear and mastoid
0.998 0.002 0.000
Z95.4 Presence of other heart-valve replacement
0.998 0.002 0.000
Z95.1 Presence of aortocoronary bypass graft
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
I20 Angina pectoris
0.998 0.002 0.000
F40 Phobic anxiety disorders
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.995 0.005 0.000
F10.0 Acute intoxication
0.994 0.006 0.000
F40.2 Specific (isolated) phobias
0.994 0.006 0.000
X60-X84 Intentional self-harm
0.991 0.009 0.000
I51.8 Other ill-defined heart diseases
0.989 0.011 0.000
H21 Other disorders of iris and ciliary body
0.989 0.011 0.000
H72 Perforation of tympanic membrane
0.989 0.011 0.000
F10.3 Withdrawal state
0.989 0.011 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.988 0.012 0.000
M80-M85 Disorders of bone density and structure
0.986 0.014 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.986 0.014 0.000
Q23 Congenital malformations of aortic and mitral valves
0.985 0.015 0.000
H16 Keratitis
0.979 0.021 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.979 0.021 0.000
I35.0 Aortic (valve) stenosis
0.978 0.022 0.000
H65 Nonsuppurative otitis media
0.978 0.022 0.000
F60-F69 Disorders of adult personality and behaviour
0.973 0.027 0.000
I08.0 Disorders of both mitral and aortic valves
0.971 0.029 0.000
T42.4 Benzodiazepines
0.971 0.029 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.969 0.031 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.969 0.031 0.000
H16.0 Corneal ulcer
0.968 0.032 0.000
F11 Mental and behavioural disorders due to use of opioids
0.968 0.032 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.966 0.034 0.000
M85 Other disorders of bone density and structure
0.966 0.034 0.000
M80 Osteoporosis with pathological fracture
0.965 0.035 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.964 0.036 0.000
T40.2 Other opioids
0.964 0.036 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.961 0.039 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.961 0.039 0.000
Z95.0 Presence of cardiac pacemaker
0.960 0.040 0.000
Q25 Congenital malformations of great arteries
0.957 0.043 0.000
F43 Reaction to severe stress, and adjustment disorders
0.955 0.045 0.000
H18 Other disorders of cornea
0.953 0.047 0.000
Q50-Q56 Congenital malformations of genital organs
0.948 0.052 0.000
Y88 Sequelae of surgical and medical care as external cause
0.948 0.052 0.000
F44 Dissociative [conversion] disorders
0.947 0.053 0.000
I37 Pulmonary valve disorders
0.944 0.056 0.000
I25.1 Atherosclerotic heart disease
0.944 0.056 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.941 0.059 0.000
X62.9 Unspecified place
0.940 0.060 0.000
F11.2 Dependence syndrome
0.940 0.060 0.000
M40-M43 Deforming dorsopathies
0.937 0.063 0.000
F43.1 Posttraumatic stress disorder
0.935 0.065 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.934 0.066 0.000
Q23.1 Congenital insufficiency of aortic valve
0.934 0.066 0.000
Q43 Other congenital malformations of intestine
0.933 0.067 0.000
I10-I15 Hypertensive diseases
0.932 0.068 0.000
I51.4 Myocarditis, unspecified
0.931 0.069 0.000
I11 Hypertensive heart disease
0.930 0.070 0.000
V01-V09 Pedestrian injured in transport accident
0.927 0.073 0.000
V40-V49 Car occupant injured in transport accident
0.925 0.075 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.923 0.077 0.000
H21.0 Hyphaema
0.919 0.081 0.000
H70 Mastoiditis and related conditions
0.915 0.085 0.000
Q27 Other congenital malformations of peripheral vascular system
0.909 0.091 0.000
I37.1 Pulmonary valve insufficiency
0.906 0.094 0.000
M85.0 Fibrous dysplasia (monostotic)
0.904 0.096 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.904 0.096 0.000
M85.6 Other cyst of bone
0.904 0.096 0.000
H65.4 Other chronic nonsuppurative otitis media
0.901 0.099 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.901 0.099 0.000
H65.2 Chronic serous otitis media
0.899 0.101 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.898 0.102 0.000
X78 Intentional self-harm by sharp object
0.898 0.102 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.897 0.103 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.893 0.107 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.893 0.107 0.000
M41 Scoliosis
0.892 0.108 0.000
Q60-Q64 Congenital malformations of the urinary system
0.892 0.108 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.892 0.108 0.000
D80-D89 Certain disorders involving the immune mechanism
0.892 0.108 0.000
F60 Specific personality disorders
0.892 0.108 0.000
T36 Poisoning by systemic antibiotics
0.891 0.109 0.000
F44.4 Dissociative motor disorders
0.890 0.110 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.889 0.110 0.000
D80 Immunodeficiency with predominantly antibody defects
0.888 0.112 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.887 0.113 0.000
I50.9 Heart failure, unspecified
0.885 0.115 0.000
Q23.0 Congenital stenosis of aortic valve
0.885 0.115 0.000
I51.9 Heart disease, unspecified
0.885 0.115 0.000
M60-M63 Disorders of muscles
0.884 0.116 0.000
Z95.2 Presence of prosthetic heart valve
0.883 0.117 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.881 0.119 0.000
F10.4 Withdrawal state with delirium
0.879 0.121 0.000
H10-H13 Disorders of conjunctiva
0.878 0.122 0.000
M86-M90 Other osteopathies
0.876 0.124 0.000
H20 Iridocyclitis
0.868 0.132 0.000
Q43.8 Other specified congenital malformations of intestine
0.868 0.132 0.000
H65.3 Chronic mucoid otitis media
0.867 0.133 0.000
H21.8 Other specified disorders of iris and ciliary body
0.865 0.135 0.000
H18.1 Bullous keratopathy
0.864 0.136 0.000
V48 Car occupant injured in noncollision transport accident
0.861 0.139 0.000
F99-F99 Unspecified mental disorder
0.860 0.140 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.860 0.140 0.000
M89 Other disorders of bone
0.860 0.140 0.000
H15 Disorders of sclera
0.859 0.141 0.000
Y89 Sequelae of other external causes
0.859 0.141 0.000
M41.9 Scoliosis, unspecified
0.859 0.141 0.000
Q51 Congenital malformations of uterus and cervix
0.857 0.143 0.000
I45 Other conduction disorders
0.857 0.143 0.000
Q52 Other congenital malformations of female genitalia
0.855 0.145 0.000
I42 Cardiomyopathy
0.854 0.146 0.000
M82 Osteoporosis in diseases classified elsewhere
0.854 0.146 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.852 0.148 0.000
F61 Mixed and other personality disorders
0.852 0.148 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.851 0.149 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.850 0.150 0.000
I60-I69 Cerebrovascular diseases
0.848 0.152 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.845 0.155 0.000
V09 Pedestrian injured in other and unspecified transport accidents
0.845 0.155 0.000
H90-H95 Other disorders of ear
0.844 0.156 0.000
F40.0 Agoraphobia
0.841 0.159 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.839 0.161 0.000
I45.9 Conduction disorder, unspecified
0.839 0.161 0.000
Q25.4 Other congenital malformations of aorta
0.838 0.162 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.838 0.162 0.000
Q23.3 Congenital mitral insufficiency
0.837 0.163 0.000
M84 Disorders of continuity of bone
0.836 0.164 0.000
H21.2 Degeneration of iris and ciliary body
0.835 0.165 0.000
I35.1 Aortic (valve) insufficiency
0.834 0.166 0.000
M89.8 Other specified disorders of bone
0.834 0.166 0.000
X78.0 Home
0.832 0.168 0.000
I61 Intracerebral haemorrhage
0.832 0.168 0.000
D84 Other immunodeficiencies
0.831 0.169 0.000
Q00-Q07 Congenital malformations of the nervous system
0.829 0.171 0.000
F11.3 Withdrawal state
0.828 0.172 0.000
F69 Unspecified disorder of adult personality and behaviour
0.827 0.173 0.000
Q27.3 Peripheral arteriovenous malformation
0.827 0.173 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.826 0.174 0.000
I05 Rheumatic mitral valve diseases
0.826 0.174 0.000
I25.5 Ischaemic cardiomyopathy
0.820 0.180 0.000
I08.8 Other multiple valve diseases
0.819 0.181 0.000
M80.8 Other osteoporosis with pathological fracture
0.818 0.182 0.000
I09 Other rheumatic heart diseases
0.816 0.183 0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.816 0.184 0.000
H18.4 Corneal degeneration
0.816 0.184 0.000
M00-M03 Infectious arthropathies
0.816 0.184 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.816 0.184 0.000
I40 Acute myocarditis
0.816 0.184 0.000
Q24 Other congenital malformations of heart
0.814 0.186 0.000
F12.1 Harmful use
0.814 0.186 0.000
H74 Other disorders of middle ear and mastoid
0.814 0.186 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.813 0.187 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.813 0.187 0.000
Q61 Cystic kidney disease
0.813 0.187 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.813 0.187 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.812 0.188 0.000
Q25.1 Coarctation of aorta
0.812 0.188 0.000
M45-M49 Spondylopathies
0.812 0.188 0.000
H20.0 Acute and subacute iridocyclitis
0.811 0.189 0.000
M84.0 Malunion of fracture
0.811 0.189 0.000
X30-X39 Exposure to forces of nature
0.811 0.189 0.000
I42.8 Other cardiomyopathies
0.808 0.192 0.000
M40 Kyphosis and lordosis
0.808 0.192 0.000
I25.3 Aneurysm of heart
0.808 0.192 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.806 0.194 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.805 0.195 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.803 0.197 0.000
Q40 Other congenital malformations of upper alimentary tract
0.802 0.198 0.000
V90-V94 Water transport accidents
0.802 0.198 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.801 0.199 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.801 0.199 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.800 0.200 0.000
Q28 Other congenital malformations of circulatory system
0.800 0.200 0.000
Q39 Congenital malformations of oesophagus
0.799 0.200 0.000
F60.9 Personality disorder, unspecified
0.798 0.202 0.000
H70.9 Mastoiditis, unspecified
0.798 0.202 0.000
F10.5 Psychotic disorder
0.795 0.205 0.000
M89.5 Osteolysis
0.793 0.207 0.000
T42.0 Hydantoin derivatives
0.793 0.207 0.000
D84.9 Immunodeficiency, unspecified
0.793 0.207 0.000
M85.9 Disorder of bone density and structure, unspecified
0.792 0.208 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.792 0.208 0.000
Q25.3 Stenosis of aorta
0.791 0.209 0.000
V20-V29 Motorcycle rider injured in transport accident
0.791 0.209 0.000
F60.3 Emotionally unstable personality disorder
0.791 0.209 0.000
F19.2 Dependence syndrome
0.788 0.212 0.000
X50-X57 Overexertion, travel and privation
0.787 0.213 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.787 0.213 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.787 0.213 0.000
T36.0 Penicillins
0.786 0.214 0.000
Y89.9 Sequelae of unspecified external cause
0.786 0.214 0.000
H65.1 Other acute nonsuppurative otitis media
0.784 0.216 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.784 0.216 0.000
V98-V99 Other and unspecified transport accidents
0.783 0.217 0.000
H71 Cholesteatoma of middle ear
0.783 0.217 0.000
I51.6 Cardiovascular disease, unspecified
0.782 0.218 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.780 0.220 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.779 0.221 0.000
Y00-Y09 Assault
0.778 0.222 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.778 0.222 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.778 0.222 0.000
F10.7 Residual and late-onset psychotic disorder
0.777 0.223 0.000
T42.3 Barbiturates
0.777 0.223 0.000
I42.0 Dilated cardiomyopathy
0.777 0.223 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.777 0.223 0.000
V48.6 Passenger injured in traffic accident
0.777 0.223 0.000
M85.2 Hyperostosis of skull
0.776 0.224 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.776 0.224 0.000
Q52.5 Fusion of labia
0.776 0.224 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.774 0.226 0.000
F40.8 Other phobic anxiety disorders
0.773 0.227 0.000
Q25.0 Patent ductus arteriosus
0.773 0.227 0.000
H11 Other disorders of conjunctiva
0.772 0.228 0.000
H18.6 Keratoconus
0.772 0.228 0.000
I05.2 Mitral stenosis with insufficiency
0.771 0.229 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.771 0.229 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.770 0.230 0.000
Q61.0 Congenital single renal cyst
0.770 0.230 0.000
I06 Rheumatic aortic valve diseases
0.770 0.230 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.769 0.230 0.000
H18.5 Hereditary corneal dystrophies
0.767 0.233 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.767 0.233 0.000
I61.8 Other intracerebral haemorrhage
0.766 0.234 0.000
V80-V89 Other land transport accidents
0.766 0.234 0.000
T40.6 Other and unspecified narcotics
0.765 0.235 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.765 0.235 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.764 0.236 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.763 0.237 0.000
V01 Pedestrian injured in collision with pedal cycle
0.762 0.238 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.761 0.239 0.000
F99 Mental disorder, not otherwise specified
0.760 0.240 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.760 0.240 0.000
H20.8 Other iridocyclitis
0.760 0.240 0.000
M82.1 Osteoporosis in endocrine disorders
0.759 0.240 0.000
H18.0 Corneal pigmentations and deposits
0.759 0.241 0.000
M46 Other inflammatory spondylopathies
0.759 0.241 0.000
Q54 Hypospadias
0.759 0.241 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.759 0.241 0.000
M60 Myositis
0.759 0.241 0.000
H21.4 Pupillary membranes
0.758 0.241 0.000
F50 Eating disorders
0.756 0.244 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.756 0.244 0.000
I33 Acute and subacute endocarditis
0.754 0.246 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.753 0.247 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.753 0.247 0.000
F55 Abuse of non-dependence-producing substances
0.752 0.247 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.752 0.248 0.000
M85.64 Other cyst of bone (Hand)
0.751 0.249 0.000
H47.2 Optic atrophy
0.750 0.250 0.000
H90 Conductive and sensorineural hearing loss
0.750 0.250 0.000
V95-V97 Air and space transport accidents
0.747 0.253 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.745 0.255 0.000
F45 Somatoform disorders
0.745 0.255 0.000
F44.0 Dissociative amnesia
0.744 0.256 0.000
H70.1 Chronic mastoiditis
0.743 0.257 0.000
Q05 Spina bifida
0.742 0.258 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.741 0.259 0.000
H69 Other disorders of Eustachian tube
0.740 0.260 0.000
V04 Pedestrian injured in collision with heavy transport vehicle or bus
0.739 0.261 0.000
M62 Other disorders of muscle
0.739 0.261 0.000
F40.9 Phobic anxiety disorder, unspecified
0.738 0.262 0.000
Q45 Other congenital malformations of digestive system
0.737 0.263 0.000
X20-X29 Contact with venomous animals and plants
0.736 0.264 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.736 0.264 0.000
V09.0 Pedestrian injured in nontraffic accident involving other and unspecified motor vehicles
0.736 0.264 0.000
F43.0 Acute stress reaction
0.735 0.265 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.735 0.265 0.000
F10.8 Other mental and behavioural disorders
0.734 0.265 0.000
X58 Exposure to other specified factors
0.734 0.265 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.734 0.266 0.000
M84.03 Malunion of fracture (Forearm)
0.734 0.266 0.000
Q43.1 Hirschsprung's disease
0.732 0.267 0.000
I45.3 Trifascicular block
0.731 0.269 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.731 0.269 0.000
X10-X19 Contact with heat and hot substances
0.730 0.270 0.000
H16.3 Interstitial and deep keratitis
0.728 0.272 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.728 0.272 0.000
H16.8 Other keratitis
0.728 0.272 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.728 0.272 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.727 0.273 0.000
I35.9 Aortic valve disorder, unspecified
0.726 0.274 0.000
F19.1 Harmful use
0.724 0.276 0.000
H16.2 Keratoconjunctivitis
0.723 0.277 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.723 0.277 0.000
H55-H59 Other disorders of eye and adnexa
0.723 0.277 0.000
V70-V79 Bus occupant injured in transport accident
0.722 0.278 0.000
M83 Adult osteomalacia
0.722 0.278 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.721 0.279 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.720 0.280 0.000
M46.4 Discitis, unspecified
0.717 0.283 0.000
H70.8 Other mastoiditis and related conditions
0.717 0.283 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.717 0.283 0.000
I51.5 Myocardial degeneration
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.717 0.283 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.717 0.283 0.000
Q43.0 Meckel's diverticulum
0.717 0.283 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.716 0.283 0.000
Q26 Congenital malformations of great veins
0.716 0.283 0.000
H46 Optic neuritis
0.717 0.283 0.000
H67 Otitis media in diseases classified elsewhere
0.716 0.284 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.716 0.284 0.000
F40.1 Social phobias
0.715 0.285 0.000
M40.2 Other and unspecified kyphosis
0.714 0.286 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
H18.3 Changes in corneal membranes
0.714 0.286 0.000
Q53 Undescended testicle
0.712 0.288 0.000
F10.9 Unspecified mental and behavioural disorder
0.712 0.288 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.711 0.289 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.711 0.289 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.710 0.290 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.710 0.290 0.000
X71 Intentional self-harm by drowning and submersion
0.710 0.290 0.000
X72 Intentional self-harm by handgun discharge
0.710 0.290 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.710 0.290 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.710 0.290 0.000
X75 Intentional self-harm by explosive material
0.710 0.290 0.000
X76 Intentional self-harm by smoke, fire and flames
0.710 0.290 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.710 0.290 0.000
X79 Intentional self-harm by blunt object
0.710 0.290 0.000
X80 Intentional self-harm by jumping from a high place
0.710 0.290 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.710 0.290 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.710 0.290 0.000
X83 Intentional self-harm by other specified means
0.710 0.290 0.000
X84 Intentional self-harm by unspecified means
0.710 0.290 0.000
I35.8 Other aortic valve disorders
0.710 0.290 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.709 0.291 0.000
H15.0 Scleritis
0.709 0.291 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.709 0.291 0.000
F64 Gender identity disorders
0.708 0.292 0.000
F51 Nonorganic sleep disorders
0.707 0.292 0.000
Q23.2 Congenital mitral stenosis
0.707 0.293 0.000
Q23.4 Hypoplastic left heart syndrome
0.707 0.293 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.707 0.293 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.707 0.293 0.000
F70-F79 Mental retardation
0.706 0.294 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.706 0.294 0.000
I42.4 Endocardial fibroelastosis
0.703 0.297 0.000
M84.02 Malunion of fracture (Upper arm)
0.703 0.297 0.000
T36.8 Other systemic antibiotics
0.702 0.297 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.702 0.298 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.702 0.298 0.000
H66 Suppurative and unspecified otitis media
0.702 0.298 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.701 0.299 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.701 0.299 0.000
H93 Other disorders of ear, not elsewhere classified
0.701 0.299 0.000
H65.0 Acute serous otitis media
0.700 0.300 0.000
M80.88 Other osteoporosis with pathological fracture (Other)
0.698 0.302 0.000
F63 Habit and impulse disorders
0.697 0.303 0.000
F65 Disorders of sexual preference
0.697 0.303 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.697 0.303 0.000
F68 Other disorders of adult personality and behaviour
0.697 0.303 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.697 0.303 0.000
F10.6 Amnesic syndrome
0.697 0.303 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.695 0.305 0.000
T42.2 Succinimides and oxazolidinediones
0.695 0.305 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.695 0.305 0.000
T36.3 Macrolides
0.695 0.305 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.695 0.305 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.694 0.305 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.694 0.306 0.000
V48.2 Person on outside of vehicle injured in nontraffic accident
0.694 0.306 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.694 0.306 0.000
F11.0 Acute intoxication
0.694 0.306 0.000
F11.4 Withdrawal state with delirium
0.694 0.306 0.000
F11.5 Psychotic disorder
0.694 0.306 0.000
F11.6 Amnesic syndrome
0.694 0.306 0.000
F11.7 Residual and late-onset psychotic disorder
0.694 0.306 0.000
F11.8 Other mental and behavioural disorders
0.694 0.306 0.000
F11.9 Unspecified mental and behavioural disorder
0.694 0.306 0.000
I45.6 Preexcitation syndrome
0.694 0.306 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.693 0.307 0.000
F60.8 Other specific personality disorders
0.693 0.307 0.000
M85.1 Skeletal fluorosis
0.692 0.308 0.000
M85.3 Osteitis condensans
0.692 0.308 0.000
M85.4 Solitary bone cyst
0.692 0.308 0.000
M85.5 Aneurysmal bone cyst
0.692 0.308 0.000
M84.04 Malunion of fracture (Hand)
0.692 0.308 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.692 0.308 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.692 0.308 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.692 0.308 0.000
T40.0 Opium
0.691 0.308 0.000
T40.1 Heroin
0.691 0.308 0.000
T40.3 Methadone
0.691 0.308 0.000
T40.7 Cannabis (derivatives)
0.691 0.308 0.000
T40.8 Lysergide [LSD]
0.691 0.308 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.691 0.308 0.000
V09.1 Pedestrian injured in unspecified nontraffic accident
0.689 0.311 0.000
X62.1 Residential institution
0.689 0.311 0.000
X62.2 School, other institution and public administrative area
0.689 0.311 0.000
X62.3 Sports and athletics area
0.689 0.311 0.000
X62.4 Street and highway
0.689 0.311 0.000
X62.5 Trade and service area
0.689 0.311 0.000
X62.6 Industrial and construction area
0.689 0.311 0.000
X62.7 Farm
0.689 0.311 0.000
X62.8 Other specified place
0.689 0.311 0.000
X62.0 Home
0.689 0.311 0.000
H57 Other disorders of eye and adnexa
0.689 0.311 0.000
H15.1 Episcleritis
0.689 0.311 0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)
0.689 0.311 0.000
H18.9 Disorder of cornea, unspecified
0.689 0.311 0.000
Q35-Q37 Cleft lip and cleft palate
0.688 0.312 0.000
M41.4 Neuromuscular scoliosis
0.688 0.312 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.687 0.313 0.000
M91-M94 Chondropathies
0.687 0.313 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.687 0.313 0.000
H11.0 Pterygium
0.687 0.313 0.000
I00-I02 Acute rheumatic fever
0.686 0.314 0.000
I25.6 Silent myocardial ischaemia
0.686 0.314 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.686 0.314 0.000
Q25.2 Atresia of aorta
0.686 0.314 0.000
Q25.5 Atresia of pulmonary artery
0.686 0.314 0.000
Q25.7 Other congenital malformations of pulmonary artery
0.686 0.314 0.000
Q25.8 Other congenital malformations of great arteries
0.686 0.314 0.000
Q25.9 Congenital malformation of great arteries, unspecified
0.686 0.314 0.000
W50-W64 Exposure to animate mechanical forces
0.686 0.314 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.685 0.314 0.000
T40.5 Cocaine
0.685 0.315 0.000
I09.9 Rheumatic heart disease, unspecified
0.685 0.315 0.000
F43.8 Other reactions to severe stress
0.685 0.315 0.000
H68 Eustachian salpingitis and obstruction
0.685 0.315 0.000
H18.7 Other corneal deformities
0.683 0.316 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.683 0.317 0.000
Q61.5 Medullary cystic kidney
0.683 0.317 0.000
I08.9 Multiple valve disease, unspecified
0.682 0.317 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.682 0.317 0.000
F60.7 Dependent personality disorder
0.682 0.318 0.000
Q61.2 Polycystic kidney, adult type
0.682 0.318 0.000
Q24.8 Other specified congenital malformations of heart
0.680 0.320 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.680 0.320 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.680 0.320 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.679 0.320 0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use
0.679 0.321 0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use
0.679 0.321 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.679 0.321 0.000
F44.1 Dissociative fugue
0.679 0.321 0.000
F44.2 Dissociative stupor
0.679 0.321 0.000
F44.3 Trance and possession disorders
0.679 0.321 0.000
F44.6 Dissociative anaesthesia and sensory loss
0.679 0.321 0.000
F44.7 Mixed dissociative [conversion] disorders
0.679 0.321 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.678 0.322 0.000
I25.4 Coronary artery aneurysm
0.678 0.322 0.000
H93.8 Other specified disorders of ear
0.678 0.322 0.000
X31 Exposure to excessive natural cold
0.678 0.322 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.677 0.323 0.000
I37.8 Other pulmonary valve disorders
0.677 0.323 0.000
I37.9 Pulmonary valve disorder, unspecified
0.677 0.323 0.000
X60.8 Other specified place
0.676 0.324 0.000
Q60.0 Renal agenesis, unilateral
0.675 0.325 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.675 0.325 0.000
F44.8 Other dissociative [conversion] disorders
0.674 0.326 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.674 0.326 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.674 0.326 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.673 0.327 0.000
D55-D59 Haemolytic anaemias
0.673 0.327 0.000
M40.29 Other and unspecified kyphosis (Site unspecified)
0.672 0.328 0.000
V86 Occupant of special all-terrain or other motor vehicle designed primarily for off-road use, injured in transport accident
0.672 0.328 0.000
M42 Spinal osteochondrosis
0.672 0.328 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.672 0.328 0.000
H16.4 Corneal neovascularisation
0.671 0.328 0.000
I13 Hypertensive heart and renal disease
0.669 0.330 0.000
F80-F89 Disorders of psychological development
0.669 0.331 0.000
Q43.2 Other congenital functional disorders of colon
0.669 0.331 0.000
Q43.4 Duplication of intestine
0.669 0.331 0.000
Q43.5 Ectopic anus
0.669 0.331 0.000
Q43.6 Congenital fistula of rectum and anus
0.669 0.331 0.000
Q43.7 Persistent cloaca
0.669 0.331 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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