TreeWAS – Variant ID: rs34484155

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I30-I52 Other forms of heart disease	1.000	0.000	0.000
I50 Heart failure	1.000	0.000	0.000
I50.1 Left ventricular failure	1.000	0.000	0.000
I51 Complications and ill-defined descriptions of heart disease	1.000	0.000	0.000
I51.8 Other ill-defined heart diseases	0.999	0.001	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.010	0.990
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.014	0.986
O48 Prolonged pregnancy	0.000	0.017	0.983
O36 Maternal care for other known or suspected foetal problems	0.000	0.020	0.980
O60-O75 Complications of labour and delivery	0.000	0.020	0.980
I50.0 Congestive heart failure	0.968	0.032	0.000
I47 Paroxysmal tachycardia	0.956	0.044	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.050	0.950
I42 Cardiomyopathy	0.946	0.054	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.057	0.943
I47.2 Ventricular tachycardia	0.943	0.057	0.000
I45 Other conduction disorders	0.941	0.059	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.085	0.915
O63 Long labour	0.000	0.089	0.911
I50.9 Heart failure, unspecified	0.908	0.092	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.093	0.907
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.116	0.884
O36.6 Maternal care for excessive foetal growth	0.000	0.118	0.882
I42.0 Dilated cardiomyopathy	0.869	0.131	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.136	0.864
I45.6 Preexcitation syndrome	0.859	0.141	0.000
O00-O08 Pregnancy with abortive outcome	0.000	0.146	0.854
O70 Perineal laceration during delivery	0.000	0.147	0.853
I44 Atrioventricular and left bundle-branch block	0.852	0.148	0.000
I33 Acute and subacute endocarditis	0.836	0.164	0.000
I45.9 Conduction disorder, unspecified	0.831	0.169	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.171	0.829
I31 Other diseases of pericardium	0.829	0.171	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.825	0.175	0.000
I51.9 Heart disease, unspecified	0.825	0.175	0.000
I51.7 Cardiomegaly	0.817	0.183	0.000
I42.9 Cardiomyopathy, unspecified	0.815	0.185	0.000
Chapter IX Diseases of the circulatory system	0.812	0.188	0.000
O40 Polyhydramnios	0.000	0.193	0.807
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.193	0.807
I05-I09 Chronic rheumatic heart diseases	0.805	0.195	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.195	0.805
I08 Multiple valve diseases	0.804	0.196	0.000
I49 Other cardiac arrhythmias	0.803	0.197	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.199	0.801
O63.0 Prolonged first stage (of labour)	0.000	0.207	0.793
O47 False labour	0.000	0.208	0.792
O36.5 Maternal care for poor foetal growth	0.000	0.212	0.788
O03 Spontaneous abortion	0.000	0.214	0.786
O34.1 Maternal care for tumour of corpus uteri	0.000	0.220	0.780
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.227	0.773
O44 Placenta praevia	0.000	0.231	0.769
I08.0 Disorders of both mitral and aortic valves	0.762	0.238	0.000
I44.0 Atrioventricular block, first degree	0.756	0.244	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.755	0.245	0.000
I31.3 Pericardial effusion (noninflammatory)	0.753	0.247	0.000
I51.4 Myocarditis, unspecified	0.752	0.248	0.000
O70.1 Second degree perineal laceration during delivery	0.000	0.248	0.752
I35 Nonrheumatic aortic valve disorders	0.751	0.249	0.000
I47.0 Reentry ventricular arrhythmia	0.749	0.250	0.000
O63.9 Long labour, unspecified	0.000	0.254	0.746
O63.1 Prolonged second stage (of labour)	0.000	0.255	0.745
O72 Postpartum haemorrhage	0.000	0.255	0.745
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.258	0.742
I37 Pulmonary valve disorders	0.741	0.259	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.259	0.741
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.260	0.740
I44.7 Left bundle-branch block, unspecified	0.739	0.261	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.738	0.262	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.732	0.268	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.268	0.731
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.269	0.731
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.272	0.728
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.276	0.724
O73 Retained placenta and membranes, without haemorrhage	0.000	0.277	0.723
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.277	0.723
I33.0 Acute and subacute infective endocarditis	0.719	0.281	0.000
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283	0.000
I48 Atrial fibrillation and flutter	0.717	0.283	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283	0.000
I41 Myocarditis in diseases classified elsewhere	0.717	0.283	0.000
I40 Acute myocarditis	0.717	0.283	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283	0.000
I32 Pericarditis in diseases classified elsewhere	0.717	0.283	0.000
I51.6 Cardiovascular disease, unspecified	0.717	0.283	0.000
I51.5 Myocardial degeneration	0.717	0.283	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.717	0.283	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.717	0.283	0.000
I51.0 Cardiac septal defect, acquired	0.717	0.283	0.000
O30 Multiple gestation	0.000	0.286	0.713
O03.4 Incomplete, without complication	0.000	0.287	0.713
I30 Acute pericarditis	0.710	0.290	0.000
O33 Maternal care for known or suspected disproportion	0.000	0.290	0.710
O31 Complications specific to multiple gestation	0.000	0.290	0.710
I36 Nonrheumatic tricuspid valve disorders	0.707	0.293	0.000
O61 Failed induction of labour	0.000	0.295	0.705
O70.0 First degree perineal laceration during delivery	0.000	0.297	0.703
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.297	0.703
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.297	0.703
O36.2 Maternal care for hydrops foetalis	0.000	0.297	0.703
O36.1 Maternal care for other isoimmunisation	0.000	0.297	0.703
O74 Complications of anaesthesia during labour and delivery	0.000	0.297	0.703
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.297	0.703
O60 Preterm delivery	0.000	0.297	0.703
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.300	0.700
I49.9 Cardiac arrhythmia, unspecified	0.700	0.300	0.000
I42.8 Other cardiomyopathies	0.697	0.303	0.000
O43 Placental disorders	0.000	0.310	0.690
I34 Nonrheumatic mitral valve disorders	0.689	0.311	0.000
I20-I25 Ischaemic heart diseases	0.689	0.311	0.000
O20 Haemorrhage in early pregnancy	0.000	0.312	0.688
I38 Endocarditis, valve unspecified	0.687	0.313	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.686	0.314	0.000
I45.2 Bifascicular block	0.684	0.316	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.319	0.681
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.319	0.681
O34.6 Maternal care for abnormality of vagina	0.000	0.319	0.681
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.319	0.681
O34.4 Maternal care for other abnormalities of cervix	0.000	0.319	0.681
O34.3 Maternal care for cervical incompetence	0.000	0.319	0.681
O34.0 Maternal care for congenital malformation of uterus	0.000	0.319	0.681
I46 Cardiac arrest	0.681	0.319	0.000
O66 Other obstructed labour	0.000	0.319	0.680
I44.6 Other and unspecified fascicular block	0.679	0.321	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.678	0.322	0.000
I42.6 Alcoholic cardiomyopathy	0.678	0.322	0.000
I42.5 Other restrictive cardiomyopathy	0.678	0.322	0.000
I42.4 Endocardial fibroelastosis	0.678	0.322	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.678	0.322	0.000
I45.5 Other specified heart block	0.678	0.322	0.000
I45.4 Nonspecific intraventricular block	0.675	0.325	0.000
I45.0 Right fascicular block	0.675	0.325	0.000
I25 Chronic ischaemic heart disease	0.674	0.326	0.000
I45.8 Other specified conduction disorders	0.673	0.327	0.000
O71 Other obstetric trauma	0.000	0.330	0.670
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.332	0.668
I45.3 Trifascicular block	0.664	0.336	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.338	0.662
I25.9 Chronic ischaemic heart disease, unspecified	0.661	0.339	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.342	0.658
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.344	0.656
O97 Death from sequelae of direct obstetric causes	0.000	0.344	0.656
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.344	0.656
O95 Obstetric death of unspecified cause	0.000	0.344	0.656
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.344	0.656
O47.0 False labour before 37 completed weeks of gestation	0.000	0.345	0.655
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.346	0.653
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.347	0.653
O41 Other disorders of amniotic fluid and membranes	0.000	0.350	0.650
O62 Abnormalities of forces of labour	0.000	0.351	0.649
O47.9 False labour, unspecified	0.000	0.354	0.646
O03.9 Complete or unspecified, without complication	0.000	0.361	0.639
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.363	0.637
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.365	0.635
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.366	0.634
O24 Diabetes mellitus in pregnancy	0.000	0.368	0.632
I95-I99 Other and unspecified disorders of the circulatory system	0.631	0.369	0.000
O45 Premature separation of placenta [abruptio placentae]	0.000	0.370	0.630
O02 Other abnormal products of conception	0.000	0.371	0.629
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.374	0.626
I60-I69 Cerebrovascular diseases	0.625	0.375	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.380	0.619
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.380	0.619
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.380	0.619
I67 Other cerebrovascular diseases	0.619	0.381	0.000
I35.9 Aortic valve disorder, unspecified	0.618	0.382	0.000
I49.3 Ventricular premature depolarisation	0.618	0.382	0.000
I49.0 Ventricular fibrillation and flutter	0.617	0.383	0.000
I67.9 Cerebrovascular disease, unspecified	0.613	0.387	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.000	0.388	0.612
O07 Failed attempted abortion	0.000	0.388	0.612
O06 Unspecified abortion	0.000	0.388	0.612
O05 Other abortion	0.000	0.388	0.612
O01 Hydatidiform mole	0.000	0.388	0.612
O70.3 Fourth degree perineal laceration during delivery	0.000	0.388	0.612
O44.1 Placenta praevia with haemorrhage	0.000	0.389	0.611
I44.5 Left posterior fascicular block	0.611	0.389	0.000
I44.4 Left anterior fascicular block	0.611	0.389	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.389	0.611
I45.1 Other and unspecified right bundle-branch block	0.611	0.389	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.391	0.609
O72.0 Third-stage haemorrhage	0.000	0.391	0.609
O36.4 Maternal care for intra-uterine death	0.000	0.393	0.607
O80-O84 Delivery	0.000	0.394	0.606
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.399	0.601
I33.9 Acute endocarditis, unspecified	0.599	0.400	0.000
O85-O92 Complications predominantly related to the puerperium	0.000	0.401	0.599
I25.3 Aneurysm of heart	0.598	0.402	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.402	0.598
I35.8 Other aortic valve disorders	0.597	0.403	0.000
I49.8 Other specified cardiac arrhythmias	0.596	0.404	0.000
O75.9 Complication of labour and delivery, unspecified	0.000	0.405	0.594
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.405	0.594
O75.4 Other complications of obstetric surgery and procedures	0.000	0.405	0.594
O75.3 Other infection during labour	0.000	0.405	0.594
O75.1 Shock during or following labour and delivery	0.000	0.405	0.594
O75.0 Maternal distress during labour and delivery	0.000	0.405	0.594
I31.8 Other specified diseases of pericardium	0.594	0.406	0.000
I31.2 Haemopericardium, not elsewhere classified	0.594	0.406	0.000
I31.1 Chronic constrictive pericarditis	0.594	0.406	0.000
I31.0 Chronic adhesive pericarditis	0.594	0.406	0.000
I49.4 Other and unspecified premature depolarisation	0.594	0.406	0.000
I08.8 Other multiple valve diseases	0.590	0.410	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.410	0.589
I44.3 Other and unspecified atrioventricular block	0.586	0.414	0.000
O70.9 Perineal laceration during delivery, unspecified	0.000	0.415	0.585
O20.0 Threatened abortion	0.000	0.416	0.584
I00-I02 Acute rheumatic fever	0.582	0.418	0.000
O16 Unspecified maternal hypertension	0.000	0.420	0.580
O29 Complications of anaesthesia during pregnancy	0.000	0.421	0.579
O28 Abnormal findings on antenatal screening of mother	0.000	0.421	0.579
O22 Venous complications in pregnancy	0.000	0.421	0.579
O25 Malnutrition in pregnancy	0.000	0.421	0.579
I09 Other rheumatic heart diseases	0.577	0.423	0.000
I06 Rheumatic aortic valve diseases	0.577	0.423	0.000
I08.9 Multiple valve disease, unspecified	0.576	0.424	0.000
I42.2 Other hypertrophic cardiomyopathy	0.576	0.424	0.000
I49.2 Junctional premature depolarisation	0.576	0.424	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.424	0.576
I47.9 Paroxysmal tachycardia, unspecified	0.575	0.425	0.000
O04 Medical abortion	0.000	0.426	0.574
O21 Excessive vomiting in pregnancy	0.000	0.428	0.572
I34.0 Mitral (valve) insufficiency	0.569	0.431	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.431	0.569
I05 Rheumatic mitral valve diseases	0.568	0.432	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.436	0.564
O03.7 Complete or unspecified, complicated by embolism	0.000	0.436	0.564
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.436	0.564
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.436	0.564
O03.3 Incomplete, with other and unspecified complications	0.000	0.436	0.564
O03.2 Incomplete, complicated by embolism	0.000	0.436	0.564
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.436	0.564
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.436	0.564
I95 Hypotension	0.562	0.438	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.438	0.562
I37.1 Pulmonary valve insufficiency	0.556	0.444	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.446	0.554
I08.2 Disorders of both aortic and tricuspid valves	0.553	0.446	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.447	0.553
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.448	0.551
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.452	0.548
O00 Ectopic pregnancy	0.000	0.457	0.543
O43.8 Other placental disorders	0.000	0.458	0.542
O70.2 Third degree perineal laceration during delivery	0.000	0.459	0.541
O73.0 Retained placenta, without haemorrhage	0.000	0.461	0.539
O72.3 Postpartum coagulation defects	0.000	0.466	0.534
I25.5 Ischaemic cardiomyopathy	0.532	0.468	0.000
I37.9 Pulmonary valve disorder, unspecified	0.532	0.468	0.000
I37.8 Other pulmonary valve disorders	0.532	0.468	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.532	0.468	0.000
I37.0 Pulmonary valve stenosis	0.532	0.468	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.469	0.531
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.469	0.531
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.469	0.531
O69.3 Labour and delivery complicated by short cord	0.000	0.469	0.531
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.469	0.531
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.469	0.531
O64.8 Obstructed labour due to other malposition and malpresentation	0.000	0.469	0.531
O64.5 Obstructed labour due to compound presentation	0.000	0.469	0.531
O64.4 Obstructed labour due to shoulder presentation	0.000	0.469	0.531
O64.3 Obstructed labour due to brow presentation	0.000	0.469	0.531
O64.2 Obstructed labour due to face presentation	0.000	0.469	0.531
O72.1 Other immediate postpartum haemorrhage	0.000	0.470	0.530
I67.2 Cerebral atherosclerosis	0.529	0.471	0.000
I49.1 Atrial premature depolarisation	0.528	0.472	0.000
O69.8 Labour and delivery complicated by other cord complications	0.000	0.475	0.524
O67.8 Other intrapartum haemorrhage	0.000	0.475	0.524
O67.0 Intrapartum haemorrhage with coagulation defect	0.000	0.475	0.524
O15 Eclampsia	0.000	0.476	0.524
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.476	0.524
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.476	0.524
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.479	0.520
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.481	0.519
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.481	0.519
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.481	0.519
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.481	0.519
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.481	0.519
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.481	0.519
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.481	0.519
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.481	0.519
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.000	0.481	0.518
O42 Premature rupture of membranes	0.000	0.482	0.518
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.483	0.517
I95.1 Orthostatic hypotension	0.517	0.483	0.000
O30.0 Twin pregnancy	0.000	0.485	0.515
I22 Subsequent myocardial infarction	0.514	0.486	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.514	0.486	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.514	0.486	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.514	0.486	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.514	0.486	0.000
I40.9 Acute myocarditis, unspecified	0.514	0.486	0.000
I40.8 Other acute myocarditis	0.514	0.486	0.000
I40.1 Isolated myocarditis	0.514	0.486	0.000
I40.0 Infective myocarditis	0.514	0.486	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.514	0.486	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.514	0.486	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.514	0.486	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.514	0.486	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.514	0.486	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.514	0.486	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.514	0.486	0.000
I48.4 Atypical atrial flutter	0.514	0.486	0.000
I48.3 Typical atrial flutter	0.514	0.486	0.000
I48.2 Chronic atrial fibrillation	0.514	0.486	0.000
I48.1 Persistent atrial fibrillation	0.514	0.486	0.000
I48.0 Paroxysmal atrial fibrillation	0.514	0.486	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.514	0.486	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.514	0.486	0.000
O30.9 Multiple gestation, unspecified	0.000	0.488	0.512
O30.8 Other multiple gestation	0.000	0.488	0.512
O30.2 Quadruplet pregnancy	0.000	0.488	0.512
O30.1 Triplet pregnancy	0.000	0.488	0.512
I30.8 Other forms of acute pericarditis	0.509	0.491	0.000
I30.1 Infective pericarditis	0.509	0.491	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.509	0.491	0.000
O31.8 Other complications specific to multiple gestation	0.000	0.491	0.509
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.491	0.509
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.491	0.509
O31.0 Papyraceous foetus	0.000	0.491	0.509
O33.9 Maternal care for disproportion, unspecified	0.000	0.491	0.509
O33.8 Maternal care for disproportion of other origin	0.000	0.491	0.509
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.491	0.509
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.491	0.509
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.491	0.509
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.491	0.509
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.491	0.509
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.491	0.509
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.491	0.509
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.491	0.509
O61.0 Failed medical induction of labour	0.000	0.492	0.508
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.493	0.507
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.507	0.493	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.507	0.493	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.507	0.493	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.507	0.493	0.000
O61.9 Failed induction of labour, unspecified	0.000	0.494	0.505
O61.8 Other failed induction of labour	0.000	0.494	0.505
O61.1 Failed instrumental induction of labour	0.000	0.494	0.505
O20.8 Other haemorrhage in early pregnancy	0.000	0.495	0.505
O60.3 Preterm delivery without spontaneous labour	0.000	0.496	0.504
O60.2 Preterm spontaneous labour with term delivery	0.000	0.496	0.504
O60.1 Preterm spontaneous labour with preterm delivery	0.000	0.496	0.504
O60.0 Preterm labour without delivery	0.000	0.496	0.504
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.000	0.496	0.504
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.000	0.496	0.504
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.000	0.496	0.504
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.000	0.496	0.504
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.000	0.496	0.504
O65.2 Obstructed labour due to pelvic inlet contraction	0.000	0.496	0.504
O65.1 Obstructed labour due to generally contracted pelvis	0.000	0.496	0.504
O65.0 Obstructed labour due to deformed pelvis	0.000	0.496	0.504
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.000	0.496	0.504
O74.8 Other complications of anaesthesia during labour and delivery	0.000	0.496	0.504
O74.7 Failed or difficult intubation during labour and delivery	0.000	0.496	0.504
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.000	0.496	0.504
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.000	0.496	0.504
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.000	0.496	0.504
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.000	0.496	0.504
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.000	0.496	0.504
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.000	0.496	0.504
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.000	0.496	0.504
I30.9 Acute pericarditis, unspecified	0.502	0.498	0.000
O64.1 Obstructed labour due to breech presentation	0.000	0.499	0.501
O23 Infections of genito-urinary tract in pregnancy	0.000	0.503	0.497
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.497	0.503	0.000
I20 Angina pectoris	0.497	0.503	0.000
O02.1 Missed abortion	0.000	0.503	0.497
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.496	0.504	0.000
I44.1 Atrioventricular block, second degree	0.495	0.504	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.504	0.495
O43.9 Placental disorder, unspecified	0.000	0.505	0.495
O43.2 Morbidly adherent placenta	0.000	0.505	0.495
O43.0 Placental transfusion syndromes	0.000	0.505	0.495
I34.8 Other nonrheumatic mitral valve disorders	0.494	0.506	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.494	0.506	0.000
I23 Certain current complications following acute myocardial infarction	0.494	0.506	0.000
O26.8 Other specified pregnancy-related conditions	0.000	0.508	0.492
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.511	0.489
I46.1 Sudden cardiac death, so described	0.488	0.512	0.000
O66.9 Obstructed labour, unspecified	0.000	0.512	0.488
O66.8 Other specified obstructed labour	0.000	0.512	0.488
O66.4 Failed trial of labour, unspecified	0.000	0.512	0.488
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.512	0.488
O66.2 Obstructed labour due to unusually large foetus	0.000	0.512	0.488
O66.1 Obstructed labour due to locked twins	0.000	0.512	0.488
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.512	0.488
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.516	0.483
I25.6 Silent myocardial ischaemia	0.483	0.517	0.000
I25.4 Coronary artery aneurysm	0.483	0.517	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.483	0.517	0.000
I46.0 Cardiac arrest with successful resuscitation	0.481	0.519	0.000
O71.9 Obstetric trauma, unspecified	0.000	0.520	0.480
O71.8 Other specified obstetric trauma	0.000	0.520	0.480
O71.7 Obstetric haematoma of pelvis	0.000	0.520	0.480
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.520	0.480
O71.5 Other obstetric injury to pelvic organs	0.000	0.520	0.480
O71.3 Obstetric laceration of cervix	0.000	0.520	0.480
O71.2 Postpartum inversion of uterus	0.000	0.520	0.480
O71.1 Rupture of uterus during labour	0.000	0.520	0.480
O71.0 Rupture of uterus before onset of labour	0.000	0.520	0.480
I07 Rheumatic tricuspid valve diseases	0.478	0.522	0.000
I20.9 Angina pectoris, unspecified	0.477	0.523	0.000
O96.9 Death from unspecified obstetric cause	0.000	0.529	0.470
O96.1 Death from indirect obstetric cause	0.000	0.529	0.470
O96.0 Death from direct obstetric cause	0.000	0.529	0.470
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.529	0.470
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.529	0.470
O97.0 Death from sequelae of direct obstetric cause	0.000	0.529	0.470
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.529	0.470
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.466	0.533	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.534	0.466
O41.1 Infection of amniotic sac and membranes	0.000	0.534	0.466
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.534	0.466
O62.9 Abnormality of forces of labour, unspecified	0.000	0.534	0.465
O62.8 Other abnormalities of forces of labour	0.000	0.534	0.465
O62.3 Precipitate labour	0.000	0.534	0.465
O62.1 Secondary uterine inertia	0.000	0.534	0.465
O62.0 Primary inadequate contractions	0.000	0.534	0.465
I46.9 Cardiac arrest, unspecified	0.461	0.539	0.000
O62.2 Other uterine inertia	0.000	0.539	0.460
I25.2 Old myocardial infarction	0.459	0.541	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.546	0.453
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.546	0.453
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.546	0.453
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.546	0.453
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.546	0.453
O14.9 Preeclampsia, unspecified	0.000	0.547	0.453
I95.9 Hypotension, unspecified	0.453	0.547	0.000
O45.8 Other premature separation of placenta	0.000	0.548	0.452
O45.0 Premature separation of placenta with coagulation defect	0.000	0.548	0.452
O02.9 Abnormal product of conception, unspecified	0.000	0.549	0.451
O02.8 Other specified abnormal products of conception	0.000	0.549	0.451
I31.9 Disease of pericardium, unspecified	0.449	0.550	0.000
I05.2 Mitral stenosis with insufficiency	0.449	0.551	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.449	0.551	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.448	0.552	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.448	0.552	0.000
O71.4 Obstetric high vaginal laceration alone	0.000	0.552	0.447
I67.7 Cerebral arteritis, not elsewhere classified	0.444	0.556	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.444	0.556	0.000
I67.5 Moyamoya disease	0.444	0.556	0.000
I67.4 Hypertensive encephalopathy	0.444	0.556	0.000
I67.3 Progressive vascular leukoencephalopathy	0.444	0.556	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.444	0.556	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.442	0.558	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.559	0.441
I05.1 Rheumatic mitral insufficiency	0.441	0.559	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.560	0.440
O01.9 Hydatidiform mole, unspecified	0.000	0.561	0.439
O01.1 Incomplete and partial hydatidiform mole	0.000	0.561	0.439
O01.0 Classical hydatidiform mole	0.000	0.561	0.439
O05.9 Complete or unspecified, without complication	0.000	0.561	0.439
O05.8 Complete or unspecified, with other and unspecified complications	0.000	0.561	0.439
O05.7 Complete or unspecified, complicated by embolism	0.000	0.561	0.439
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.561	0.439
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.561	0.439
O05.4 Incomplete, without complication	0.000	0.561	0.439
O05.3 Incomplete, with other and unspecified complications	0.000	0.561	0.439
O05.2 Incomplete, complicated by embolism	0.000	0.561	0.439
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.561	0.439
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.561	0.439
O06.9 Complete or unspecified, without complication	0.000	0.561	0.439
O06.8 Complete or unspecified, with other and unspecified complications	0.000	0.561	0.439
O06.7 Complete or unspecified, complicated by embolism	0.000	0.561	0.439
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.561	0.439
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.561	0.439
O06.4 Incomplete, without complication	0.000	0.561	0.439
O06.3 Incomplete, with other and unspecified complications	0.000	0.561	0.439
O06.2 Incomplete, complicated by embolism	0.000	0.561	0.439
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.561	0.439
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.561	0.439
O07.9 Other and unspecified failed attempted abortion, without complication	0.000	0.561	0.439
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.000	0.561	0.439
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.000	0.561	0.439
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.000	0.561	0.439
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.000	0.561	0.439
O07.4 Failed medical abortion, without complication	0.000	0.561	0.439
O07.3 Failed medical abortion, with other and unspecified complications	0.000	0.561	0.439
O07.2 Failed medical abortion, complicated by embolism	0.000	0.561	0.439
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.000	0.561	0.439
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.000	0.561	0.439
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.000	0.561	0.439
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.000	0.561	0.439

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations