TreeWAS – Variant ID: rs7165042

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20.8 Other forms of angina pectoris	0.990	0.010	0.000
I24 Other acute ischaemic heart diseases	0.976	0.024	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.972	0.028	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.958	0.042	0.000
I22 Subsequent myocardial infarction	0.895	0.105	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.883	0.117	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.883	0.117	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.876	0.124	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.861	0.139	0.000
I23 Certain current complications following acute myocardial infarction	0.810	0.190	0.000
I20.1 Angina pectoris with documented spasm	0.754	0.246	0.000
I22.8 Subsequent myocardial infarction of other sites	0.735	0.265	0.000
I24.1 Dressler's syndrome	0.707	0.293	0.000
I23.8 Other current complications following acute myocardial infarction	0.644	0.356	0.000
I25.6 Silent myocardial ischaemia	0.629	0.370	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.623	0.377	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.610	0.390	0.000
I25.3 Aneurysm of heart	0.590	0.409	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.581	0.419	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.581	0.419	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.581	0.419	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.581	0.419	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.581	0.419	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.581	0.419	0.000
I25.4 Coronary artery aneurysm	0.474	0.525	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.415	0.585	0.000
I25.5 Ischaemic cardiomyopathy	0.359	0.641	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.287	0.713	0.000
I21 Acute myocardial infarction	0.267	0.733	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.210	0.790	0.000
I24.8 Other forms of acute ischaemic heart disease	0.202	0.798	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.194	0.806	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.192	0.808	0.000
I21.9 Acute myocardial infarction, unspecified	0.185	0.815	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.156	0.844	0.000
I25.2 Old myocardial infarction	0.147	0.853	0.000
Z95.1 Presence of aortocoronary bypass graft	0.142	0.858	0.000
I21.4 Acute subendocardial myocardial infarction	0.131	0.869	0.000
I20.0 Unstable angina	0.129	0.871	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.101	0.891	0.007
Z95 Presence of cardiac and vascular implants and grafts	0.094	0.906	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.940	0.060
Z95.3 Presence of xenogenic heart valve	0.054	0.946	0.000
L03.3 Cellulitis of trunk	0.038	0.962	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.036	0.964	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.032	0.968	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.031	0.969	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.027	0.973	0.000
Z82.1 Family history of blindness and visual loss	0.026	0.974	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.974	0.026
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.026	0.974	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.026	0.974	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.025	0.975	0.000
Z82.2 Family history of deafness and hearing loss	0.025	0.975	0.000
J43.9 Emphysema, unspecified	0.000	0.978	0.022
I21.1 Acute transmural myocardial infarction of inferior wall	0.020	0.980	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.981	0.019
F81.9 Developmental disorder of scholastic skills, unspecified	0.018	0.982	0.000
M45 Ankylosing spondylitis	0.017	0.983	0.000
J43 Emphysema	0.000	0.983	0.017
J43.2 Centrilobular emphysema	0.000	0.984	0.016
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.016	0.984	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.015	0.985	0.000
J43.8 Other emphysema	0.000	0.986	0.014
M45.X6 Ankylosing spondylitis (Lumbar region)	0.013	0.987	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.012	0.987	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.012	0.987	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.012	0.987	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.012	0.987	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.012	0.987	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.012	0.987	0.000
J43.1 Panlobular emphysema	0.000	0.988	0.012
J43.0 MacLeod's syndrome	0.000	0.988	0.012
M45.X2 Ankylosing spondylitis (Cervical region)	0.012	0.988	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.988	0.012
K55.2 Angiodysplasia of colon	0.000	0.989	0.011
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.009	0.990	0.001
F81 Specific developmental disorders of scholastic skills	0.010	0.990	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.991	0.009
C34.3 Lower lobe, bronchus or lung	0.000	0.991	0.009
C34.2 Middle lobe, bronchus or lung	0.000	0.992	0.008
C34.1 Upper lobe, bronchus or lung	0.000	0.992	0.008
F81.8 Other developmental disorders of scholastic skills	0.007	0.993	0.000
F81.3 Mixed disorder of scholastic skills	0.007	0.993	0.000
F81.2 Specific disorder of arithmetical skills	0.007	0.993	0.000
F81.1 Specific spelling disorder	0.007	0.993	0.000
F81.0 Specific reading disorder	0.007	0.993	0.000
C34.0 Main bronchus	0.000	0.993	0.007
H35.3 Degeneration of macula and posterior pole	0.000	0.993	0.007
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.993	0.007
Z82.3 Family history of stroke	0.007	0.993	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.994	0.006
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.994	0.006
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.994	0.006
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.994	0.006
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
C33 Malignant neoplasm of trachea	0.000	0.995	0.005
F20.9 Schizophrenia, unspecified	0.000	0.995	0.005
C32 Malignant neoplasm of larynx	0.000	0.995	0.005
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.995	0.005
T40.2 Other opioids	0.000	0.995	0.005
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.995	0.005
W19.4 Street and highway	0.000	0.995	0.005
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.995	0.005
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.995	0.005
C32.9 Larynx, unspecified	0.000	0.995	0.005
F20 Schizophrenia	0.000	0.995	0.005
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.995	0.005
S06.3 Focal brain injury	0.000	0.995	0.005
T43.6 Psychostimulants with abuse potential	0.000	0.995	0.005
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.995	0.005
F20.0 Paranoid schizophrenia	0.000	0.995	0.005
T43.9 Psychotropic drug, unspecified	0.000	0.995	0.004
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.996	0.004
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.996	0.004
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.996	0.004
D86.9 Sarcoidosis, unspecified	0.000	0.996	0.004
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.996	0.004
C31 Malignant neoplasm of accessory sinuses	0.000	0.996	0.004
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.996	0.004
Z95.4 Presence of other heart-valve replacement	0.004	0.996	0.000
F80-F89 Disorders of psychological development	0.004	0.996	0.000
S32.50 Fracture of pubis (closed)	0.000	0.996	0.004
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.996	0.004
S92.50 Fracture of other toe (closed)	0.004	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
C32.2 Subglottis	0.000	0.996	0.004
F20.8 Other schizophrenia	0.000	0.996	0.004
D25.0 Submucous leiomyoma of uterus	0.004	0.996	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.996	0.004
C32.0 Glottis	0.000	0.996	0.004
C32.8 Overlapping lesion of larynx	0.000	0.996	0.004
C32.3 Laryngeal cartilage	0.000	0.996	0.004
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.996	0.004
S92.5 Fracture of other toe	0.004	0.996	0.000
T40.6 Other and unspecified narcotics	0.000	0.996	0.004
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.004	0.996	0.000
F20.2 Catatonic schizophrenia	0.000	0.996	0.004
H43.8 Other disorders of vitreous body	0.000	0.996	0.004
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.996	0.003
C32.1 Supraglottis	0.000	0.996	0.004
F20.6 Simple schizophrenia	0.000	0.996	0.004
F20.4 Postschizophrenic depression	0.000	0.996	0.004
F20.3 Undifferentiated schizophrenia	0.000	0.996	0.004
F20.1 Hebephrenic schizophrenia	0.000	0.996	0.004
F20.5 Residual schizophrenia	0.000	0.996	0.004
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.996	0.003
C38.3 Mediastinum, part unspecified	0.000	0.996	0.003
S92.51 Fracture of other toe (open)	0.004	0.996	0.000
I82.8 Embolism and thrombosis of other specified veins	0.004	0.996	0.000
S92.10 Fracture of talus (closed)	0.003	0.996	0.000
T40.4 Other synthetic narcotics	0.000	0.997	0.003
T40.1 Heroin	0.000	0.997	0.003
C39.9 Ill-defined sites within the respiratory system	0.000	0.997	0.003
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.997	0.003
C39.0 Upper respiratory tract, part unspecified	0.000	0.997	0.003
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.997	0.003
C38.2 Posterior mediastinum	0.000	0.997	0.003
C38.1 Anterior mediastinum	0.000	0.997	0.003
C38.0 Heart	0.000	0.997	0.003
S92.1 Fracture of talus	0.003	0.997	0.000
C31.9 Accessory sinus, unspecified	0.000	0.997	0.003
C31.8 Overlapping lesion of accessory sinuses	0.000	0.997	0.003
C31.3 Sphenoidal sinus	0.000	0.997	0.003
C31.2 Frontal sinus	0.000	0.997	0.003
C31.1 Ethmoidal sinus	0.000	0.997	0.003
T40.5 Cocaine	0.000	0.997	0.003
S92 Fracture of foot, except ankle	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.003
T40.8 Lysergide [LSD]	0.000	0.997	0.003
T40.7 Cannabis (derivatives)	0.000	0.997	0.003
T40.3 Methadone	0.000	0.997	0.003
T40.0 Opium	0.000	0.997	0.003
F84 Pervasive developmental disorders	0.003	0.997	0.000
I87.8 Other specified disorders of veins	0.003	0.997	0.000
F89 Unspecified disorder of psychological development	0.003	0.997	0.000
F88 Other disorders of psychological development	0.003	0.997	0.000
F83 Mixed specific developmental disorders	0.003	0.997	0.000
F82 Specific developmental disorder of motor function	0.003	0.997	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.997	0.003
K55.8 Other vascular disorders of intestine	0.000	0.997	0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
C31.0 Maxillary sinus	0.000	0.997	0.003
T42.4 Benzodiazepines	0.000	0.997	0.003
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.003	0.997	0.000
C30.1 Middle ear	0.000	0.997	0.003
M06.0 Seronegative rheumatoid arthritis	0.000	0.997	0.003
S92.0 Fracture of calcaneus	0.003	0.997	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.997	0.003
M06 Other rheumatoid arthritis	0.000	0.997	0.003
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
D25.9 Leiomyoma of uterus, unspecified	0.003	0.997	0.000
C37 Malignant neoplasm of thymus	0.000	0.997	0.003
L03.9 Cellulitis, unspecified	0.003	0.997	0.000
K62.8 Other specified diseases of anus and rectum	0.000	0.997	0.003
Z95.2 Presence of prosthetic heart valve	0.002	0.997	0.001
F80 Specific developmental disorders of speech and language	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.003	0.997	0.000
L03 Cellulitis	0.003	0.997	0.000
C38.4 Pleura	0.000	0.997	0.003
S06 Intracranial injury	0.000	0.997	0.003
K56.4 Other impaction of intestine	0.003	0.997	0.000
S92.4 Fracture of great toe	0.003	0.997	0.000
F29 Unspecified nonorganic psychosis	0.000	0.997	0.003
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.997	0.003
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.997	0.003
K55 Vascular disorders of intestine	0.000	0.997	0.003
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.997	0.003
Z95.0 Presence of cardiac pacemaker	0.003	0.997	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.997	0.003
S92.70 Multiple fractures of foot (closed)	0.003	0.997	0.000
C30.0 Nasal cavity	0.000	0.997	0.003
S92.11 Fracture of talus (open)	0.003	0.997	0.000
F80.2 Receptive language disorder	0.003	0.997	0.000
F84.0 Childhood autism	0.003	0.997	0.000
S92.40 Fracture of great toe (closed)	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.003	0.997	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.997	0.003
F84.9 Pervasive developmental disorder, unspecified	0.002	0.997	0.000
F84.8 Other pervasive developmental disorders	0.002	0.997	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.002	0.997	0.000
F84.3 Other childhood disintegrative disorder	0.002	0.997	0.000
F84.2 Rett's syndrome	0.002	0.997	0.000
F84.1 Atypical autism	0.002	0.997	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.003	0.997	0.000
F84.5 Asperger's syndrome	0.002	0.997	0.000
M06.8 Other specified rheumatoid arthritis	0.000	0.997	0.002
S99.9 Unspecified injury of ankle and foot	0.003	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.997	0.002
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.997	0.002
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.997	0.002
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.997	0.002
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.997	0.002
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.997	0.003
S06.1 Traumatic cerebral oedema	0.000	0.997	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.997	0.003
S92.01 Fracture of calcaneus (open)	0.002	0.997	0.000
F30.2 Mania with psychotic symptoms	0.003	0.997	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.003	0.997	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.997	0.003
M06.2 Rheumatoid bursitis	0.000	0.997	0.002
T85 Complications of other internal prosthetic devices, implants and grafts	0.003	0.997	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.997	0.002
S06.9 Intracranial injury, unspecified	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.000	0.998	0.002
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.998	0.002
F80.9 Developmental disorder of speech and language, unspecified	0.002	0.998	0.000
F80.8 Other developmental disorders of speech and language	0.002	0.998	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.002	0.998	0.000
F80.0 Specific speech articulation disorder	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.998	0.002
D86 Sarcoidosis	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.000	0.998	0.002
M06.1 Adult-onset Still's disease	0.000	0.998	0.002
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.998	0.002
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
Z90.5 Acquired absence of kidney	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.000	0.998	0.002
S06.0 Concussion	0.000	0.998	0.002
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.002
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.002
F30.9 Manic episode, unspecified	0.002	0.998	0.000
D25 Leiomyoma of uterus	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
F22 Persistent delusional disorders	0.000	0.998	0.002
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.998	0.002
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
M22.8 Other disorders of patella	0.002	0.998	0.000
Z33 Pregnant state, incidental	0.000	0.998	0.002
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
J18.0 Bronchopneumonia, unspecified	0.000	0.998	0.002
S06.4 Epidural haemorrhage	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.998	0.002
S72.00 Fracture of neck of femur (closed)	0.000	0.998	0.002
F22.0 Delusional disorder	0.000	0.998	0.002
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
M22.4 Chondromalacia patellae	0.002	0.998	0.000
F28 Other nonorganic psychotic disorders	0.000	0.998	0.002
F24 Induced delusional disorder	0.000	0.998	0.002
F21 Schizotypal disorder	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.998	0.002
L29.0 Pruritus ani	0.000	0.998	0.002
F30 Manic episode	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.000	0.998	0.002
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.998	0.002
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.002
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.998	0.002
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.998	0.002
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.998	0.002
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.998	0.002
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.998	0.002
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.998	0.002
S62.61 Fracture of other finger (open)	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
M06.3 Rheumatoid nodule	0.000	0.998	0.002
T85.2 Mechanical complication of intraocular lens	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.998	0.002
I82.2 Embolism and thrombosis of vena cava	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
S32.5 Fracture of pubis	0.000	0.998	0.002
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.998	0.002
M06.28 Rheumatoid bursitis (Other)	0.000	0.998	0.002
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.998	0.002
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.998	0.002
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.998	0.002
M06.24 Rheumatoid bursitis (Hand)	0.000	0.998	0.002
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.998	0.002
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.998	0.002
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.998	0.002
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.998	0.002
I87 Other disorders of veins	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.998	0.002
I72 Other aneurysm	0.000	0.998	0.002
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.998	0.002
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
K55.1 Chronic vascular disorders of intestine	0.000	0.998	0.002
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.998	0.002
M06.18 Adult-onset Still's disease (Other)	0.000	0.998	0.002
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.998	0.002
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.998	0.002
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.998	0.002
M06.14 Adult-onset Still's disease (Hand)	0.000	0.998	0.002
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.998	0.002
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.998	0.002
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.998	0.002
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.998	0.002
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.998	0.002
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.002	0.998	0.000
I82 Other venous embolism and thrombosis	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.998	0.002
S06.01 Concussion (with open intracranial wound)	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
Z29.0 Isolation	0.000	0.998	0.002
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I98.0 Cardiovascular syphilis	0.000	0.998	0.002
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.998	0.002
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.998	0.002
F30.0 Hypomania	0.002	0.998	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.998	0.002
F22.8 Other persistent delusional disorders	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.998	0.002
S06.00 Concussion (without open intracranial wound)	0.000	0.998	0.002
F01.9 Vascular dementia, unspecified	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
Y83.0 Surgical operation with transplant of whole organ	0.000	0.998	0.002
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
L03.2 Cellulitis of face	0.002	0.998	0.000
T36.0 Penicillins	0.000	0.998	0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
I87.0 Postphlebitic syndrome	0.002	0.998	0.000
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.998	0.002
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.001
M48.09 Spinal stenosis (Site unspecified)	0.000	0.998	0.002
F30.8 Other manic episodes	0.002	0.998	0.000
I87.9 Disorder of vein, unspecified	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
G80.1 Spastic diplegia	0.000	0.998	0.002
I72.1 Aneurysm of artery of upper extremity	0.000	0.998	0.002
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.998	0.002
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.998	0.002
S72.0 Fracture of neck of femur	0.000	0.998	0.002
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.998	0.002
M06.38 Rheumatoid nodule (Other)	0.000	0.998	0.002
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.998	0.002
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.998	0.002
I82.3 Embolism and thrombosis of renal vein	0.002	0.998	0.000
L60.8 Other nail disorders	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
S32.51 Fracture of pubis (open)	0.000	0.998	0.002
M75.2 Bicipital tendinitis	0.002	0.998	0.000
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
F25 Schizoaffective disorders	0.000	0.998	0.002
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
D25.1 Intramural leiomyoma of uterus	0.002	0.998	0.000
F80.1 Expressive language disorder	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.998	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.998	0.002
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.998	0.002
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
M22.2 Patellofemoral disorders	0.002	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
X23.0 Home	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
F22.9 Persistent delusional disorder, unspecified	0.000	0.998	0.001
I72.3 Aneurysm of iliac artery	0.000	0.998	0.002
T36.4 Tetracyclines	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
F23 Acute and transient psychotic disorders	0.000	0.998	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.998	0.002
I82.1 Thrombophlebitis migrans	0.002	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.002	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
T48.4 Expectorants	0.000	0.998	0.001
T48.3 Antitussives	0.000	0.998	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.001
T48.0 Oxytocic drugs	0.000	0.998	0.001
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.001
I82.9 Embolism and thrombosis of unspecified vein	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.001
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.998	0.001
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.998	0.001
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.998	0.001
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.998	0.001
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.998	0.001
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.998	0.001
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.998	0.001
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
D15.1 Heart	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.001
M22 Disorders of patella	0.002	0.998	0.000
M06.34 Rheumatoid nodule (Hand)	0.000	0.998	0.002
I47.2 Ventricular tachycardia	0.000	0.998	0.002
N42.0 Calculus of prostate	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.001
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.000	0.998	0.002
F25.1 Schizoaffective disorder, depressive type	0.000	0.998	0.001
M25.57 Pain in joint (Ankle and foot)	0.000	0.998	0.002
I72.9 Aneurysm of unspecified site	0.000	0.998	0.001
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.000	0.998	0.001
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.001
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.001
S92.31 Fracture of metatarsal bone (open)	0.001	0.998	0.000
G80.2 Infantile hemiplegia	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations