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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17514846
log Bayes Factor = 52.1536
Chromosome 15   position 91,416,550  (GRCh37) Explore rs17514846 on Ensembl!
Variant rs17514846 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.999 0.001 0.000
I21 Acute myocardial infarction
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.999 0.001 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.998 0.002 0.000
I10-I15 Hypertensive diseases
0.998 0.002 0.000
I25.2 Old myocardial infarction
0.996 0.004 0.000
I20.0 Unstable angina
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.008 0.992
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.009 0.991
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.012 0.988
E78.0 Pure hypercholesterolaemia
0.985 0.015 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.982 0.018 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.982 0.018 0.000
L03 Cellulitis
0.000 0.019 0.981
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.019 0.981
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.981 0.019 0.000
L03.3 Cellulitis of trunk
0.000 0.022 0.978
E78.5 Hyperlipidaemia, unspecified
0.975 0.025 0.000
I25.5 Ischaemic cardiomyopathy
0.968 0.032 0.000
I25.4 Coronary artery aneurysm
0.967 0.033 0.000
I21.4 Acute subendocardial myocardial infarction
0.966 0.034 0.000
Z95.1 Presence of aortocoronary bypass graft
0.957 0.043 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.951 0.049 0.000
I25.3 Aneurysm of heart
0.949 0.051 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.051 0.949
I95-I99 Other and unspecified disorders of the circulatory system
0.934 0.066 0.000
L03.8 Cellulitis of other sites
0.000 0.076 0.924
I99 Other and unspecified disorders of circulatory system
0.912 0.088 0.000
I21.9 Acute myocardial infarction, unspecified
0.911 0.089 0.000
I15 Secondary hypertension
0.902 0.098 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.900 0.100 0.000
L03.2 Cellulitis of face
0.000 0.111 0.889
E78.8 Other disorders of lipoprotein metabolism
0.887 0.113 0.000
Z95.0 Presence of cardiac pacemaker
0.886 0.114 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.884 0.116 0.000
Z95.4 Presence of other heart-valve replacement
0.875 0.125 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.859 0.141 0.000
E78.6 Lipoprotein deficiency
0.854 0.146 0.000
L03.1 Cellulitis of other parts of limb
0.000 0.156 0.844
I15.1 Hypertension secondary to other renal disorders
0.834 0.166 0.000
E78.4 Other hyperlipidaemia
0.828 0.172 0.000
I11 Hypertensive heart disease
0.825 0.175 0.000
E78.2 Mixed hyperlipidaemia
0.797 0.203 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.769 0.231 0.000
L08 Other local infections of skin and subcutaneous tissue
0.000 0.235 0.765
I13 Hypertensive heart and renal disease
0.740 0.260 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.723 0.277 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.708 0.291 0.000
L01 Impetigo
0.000 0.294 0.706
L00 Staphylococcal scalded skin syndrome
0.000 0.297 0.703
I15.0 Renovascular hypertension
0.701 0.299 0.000
I00-I02 Acute rheumatic fever
0.696 0.303 0.000
I25.6 Silent myocardial ischaemia
0.692 0.308 0.000
I23 Certain current complications following acute myocardial infarction
0.690 0.310 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.683 0.317 0.000
E78.3 Hyperchylomicronaemia
0.678 0.321 0.000
I97.1 Other functional disturbances following cardiac surgery
0.670 0.330 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.330 0.670
I97.0 Postcardiotomy syndrome
0.666 0.334 0.000
I44.7 Left bundle-branch block, unspecified
0.664 0.336 0.000
Z95.2 Presence of prosthetic heart valve
0.662 0.338 0.000
I24 Other acute ischaemic heart diseases
0.659 0.341 0.000
I44 Atrioventricular and left bundle-branch block
0.658 0.342 0.000
I30-I52 Other forms of heart disease
0.655 0.345 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.347 0.653
I05-I09 Chronic rheumatic heart diseases
0.651 0.349 0.000
L08.0 Pyoderma
0.000 0.350 0.650
I15.2 Hypertension secondary to endocrine disorders
0.647 0.353 0.000
L04 Acute lymphadenitis
0.000 0.356 0.643
I97.9 Postprocedural disorder of circulatory system, unspecified
0.641 0.359 0.000
I15.8 Other secondary hypertension
0.622 0.378 0.000
I15.9 Seconday hypertension, unspecified
0.607 0.393 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.585 0.415 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.573 0.427 0.000
I44.0 Atrioventricular block, first degree
0.569 0.431 0.000
I09 Other rheumatic heart diseases
0.565 0.435 0.000
I44.3 Other and unspecified atrioventricular block
0.562 0.438 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.556 0.444 0.000
I47 Paroxysmal tachycardia
0.551 0.449 0.000
I38 Endocarditis, valve unspecified
0.549 0.451 0.000
L08.1 Erythrasma
0.000 0.451 0.549
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.452 0.548
I47.2 Ventricular tachycardia
0.548 0.452 0.000
I24.1 Dressler's syndrome
0.548 0.452 0.000
I51 Complications and ill-defined descriptions of heart disease
0.545 0.455 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.531 0.469 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.531 0.469 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.531 0.469 0.000
I35 Nonrheumatic aortic valve disorders
0.528 0.472 0.000
I51.7 Cardiomegaly
0.525 0.475 0.000
L04.0 Acute lymphadenitis of face, head and neck
0.000 0.477 0.523
I43 Cardiomyopathy in diseases classified elsewhere
0.518 0.482 0.000
L01.0 Impetigo [any organism] [any site]
0.000 0.491 0.509
L01.1 Impetiginisation of other dermatoses
0.000 0.493 0.506
I09.9 Rheumatic heart disease, unspecified
0.503 0.496 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.501 0.499 0.000
I02 Rheumatic chorea
0.499 0.500 0.000
I01 Rheumatic fever with heart involvement
0.499 0.500 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.501 0.498
I44.4 Left anterior fascicular block
0.497 0.503 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.504 0.496
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.494 0.505 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.494 0.505 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.494 0.505 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.494 0.505 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.494 0.505 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.494 0.505 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.494 0.505 0.000
I35.0 Aortic (valve) stenosis
0.491 0.509 0.000
Z95.3 Presence of xenogenic heart valve
0.490 0.509 0.000
L03.9 Cellulitis, unspecified
0.000 0.516 0.484
I00 Rheumatic fever without mention of heart involvement
0.483 0.517 0.000
F31 Bipolar affective disorder
0.000 0.518 0.482
I08 Multiple valve diseases
0.479 0.521 0.000
I06 Rheumatic aortic valve diseases
0.476 0.524 0.000
I44.5 Left posterior fascicular block
0.472 0.528 0.000
I52 Other heart disorders in diseases classified elsewhere
0.469 0.530 0.000
I48 Atrial fibrillation and flutter
0.469 0.530 0.000
I41 Myocarditis in diseases classified elsewhere
0.469 0.530 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.469 0.530 0.000
I32 Pericarditis in diseases classified elsewhere
0.469 0.530 0.000
F30-F39 Mood [affective] disorders
0.000 0.531 0.469
I23.8 Other current complications following acute myocardial infarction
0.467 0.533 0.000
I40 Acute myocarditis
0.465 0.535 0.000
F31.9 Bipolar affective disorder, unspecified
0.000 0.535 0.465
I37 Pulmonary valve disorders
0.464 0.536 0.000
L04.8 Acute lymphadenitis of other sites
0.000 0.538 0.461
L04.3 Acute lymphadenitis of lower limb
0.000 0.538 0.461
L04.1 Acute lymphadenitis of trunk
0.000 0.540 0.459
I25.0 Atherosclerotic cardiovascular disease, so described
0.459 0.541 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.459 0.541 0.000
I44.1 Atrioventricular block, second degree
0.454 0.546 0.000
I20.8 Other forms of angina pectoris
0.449 0.551 0.000
F33 Recurrent depressive disorder
0.000 0.555 0.445
E78.1 Pure hyperglyceridaemia
0.445 0.555 0.001
I51.9 Heart disease, unspecified
0.445 0.555 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.444 0.556 0.000
I24.8 Other forms of acute ischaemic heart disease
0.444 0.556 0.000
I46 Cardiac arrest
0.443 0.557 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.000 0.558 0.442
I73 Other peripheral vascular diseases
0.437 0.563 0.000
F32 Depressive episode
0.000 0.563 0.437
I73.0 Raynaud's syndrome
0.429 0.571 0.000
I42 Cardiomyopathy
0.428 0.572 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.428 0.572 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.572 0.428
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.572 0.428
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.416 0.584 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.415 0.585 0.000
I35.1 Aortic (valve) insufficiency
0.415 0.585 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.591 0.409
L04.2 Acute lymphadenitis of upper limb
0.000 0.593 0.407
F30 Manic episode
0.000 0.594 0.406
I09.8 Other specified rheumatic heart diseases
0.405 0.595 0.000
I09.2 Chronic rheumatic pericarditis
0.405 0.595 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.405 0.595 0.000
I09.0 Rheumatic myocarditis
0.405 0.595 0.000
F33.9 Recurrent depressive disorder, unspecified
0.000 0.596 0.404
I06.9 Rheumatic aortic valve disease, unspecified
0.403 0.597 0.000
I74 Arterial embolism and thrombosis
0.402 0.598 0.000
I50 Heart failure
0.395 0.605 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.394 0.606 0.000
I42.0 Dilated cardiomyopathy
0.394 0.606 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.391 0.609 0.000
I70 Atherosclerosis
0.389 0.611 0.000
F31.7 Bipolar affective disorder, currently in remission
0.000 0.611 0.388
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.614 0.386
F32.9 Depressive episode, unspecified
0.000 0.620 0.380
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.621 0.379
I51.5 Myocardial degeneration
0.378 0.622 0.000
I22 Subsequent myocardial infarction
0.376 0.624 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.373 0.627 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.372 0.628 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.372 0.628 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.372 0.628 0.000
I44.6 Other and unspecified fascicular block
0.371 0.629 0.000
I12 Hypertensive renal disease
0.366 0.634 0.000
L04.9 Acute lymphadenitis, unspecified
0.000 0.635 0.365
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.636 0.364
I08.9 Multiple valve disease, unspecified
0.362 0.638 0.000
I51.0 Cardiac septal defect, acquired
0.362 0.638 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.362 0.638 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.359 0.641 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.358 0.642 0.000
I01.8 Other acute rheumatic heart disease
0.358 0.642 0.000
I01.2 Acute rheumatic myocarditis
0.358 0.642 0.000
I01.1 Acute rheumatic endocarditis
0.358 0.642 0.000
I01.0 Acute rheumatic pericarditis
0.358 0.642 0.000
I02.9 Rheumatic chorea without heart involvement
0.358 0.642 0.000
I02.0 Rheumatic chorea with heart involvement
0.358 0.642 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.642 0.358
I51.3 Intracardiac thrombosis, not elsewhere classified
0.357 0.643 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.643 0.357
F31.8 Other bipolar affective disorders
0.000 0.648 0.352
I40.0 Infective myocarditis
0.350 0.649 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.350 0.650 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.344 0.656 0.000
I08.0 Disorders of both mitral and aortic valves
0.343 0.657 0.000
I35.8 Other aortic valve disorders
0.341 0.659 0.000
I06.8 Other rheumatic aortic valve diseases
0.341 0.659 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.341 0.659 0.000
I46.0 Cardiac arrest with successful resuscitation
0.341 0.659 0.000
F30.2 Mania with psychotic symptoms
0.000 0.661 0.339
I50.1 Left ventricular failure
0.338 0.662 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.663 0.337
I32.8 Pericarditis in other diseases classified elsewhere
0.337 0.663 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.337 0.663 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.337 0.663 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.337 0.663 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.337 0.663 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.337 0.663 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.337 0.663 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.337 0.663 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.337 0.663 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.337 0.663 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.337 0.663 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.337 0.663 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.337 0.663 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.337 0.663 0.000
I48.4 Atypical atrial flutter
0.337 0.663 0.000
I48.3 Typical atrial flutter
0.337 0.663 0.000
I48.2 Chronic atrial fibrillation
0.337 0.663 0.000
I48.1 Persistent atrial fibrillation
0.337 0.663 0.000
I48.0 Paroxysmal atrial fibrillation
0.337 0.663 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.337 0.663 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.337 0.663 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.337 0.663 0.000
I37.0 Pulmonary valve stenosis
0.335 0.664 0.000
I36 Nonrheumatic tricuspid valve disorders
0.335 0.665 0.000
I05 Rheumatic mitral valve diseases
0.335 0.665 0.000
F30.9 Manic episode, unspecified
0.000 0.666 0.334
I40.8 Other acute myocarditis
0.333 0.666 0.000
I40.1 Isolated myocarditis
0.333 0.666 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.333 0.667 0.000
I37.9 Pulmonary valve disorder, unspecified
0.333 0.667 0.000
I37.8 Other pulmonary valve disorders
0.333 0.667 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.333 0.667 0.000
I71 Aortic aneurysm and dissection
0.333 0.667 0.000
I06.1 Rheumatic aortic insufficiency
0.330 0.670 0.000
I74.8 Embolism and thrombosis of other arteries
0.328 0.672 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.328 0.672 0.000
F34 Persistent mood [affective] disorders
0.000 0.672 0.328
F32.0 Mild depressive episode
0.000 0.673 0.327
I37.1 Pulmonary valve insufficiency
0.325 0.675 0.000
F38 Other mood [affective] disorders
0.000 0.680 0.320
I72 Other aneurysm
0.320 0.680 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.319 0.681 0.000
I46.1 Sudden cardiac death, so described
0.318 0.682 0.000
I51.4 Myocarditis, unspecified
0.317 0.683 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.315 0.685 0.000
I33 Acute and subacute endocarditis
0.313 0.687 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.313 0.687 0.000
I42.4 Endocardial fibroelastosis
0.309 0.691 0.000
I40.9 Acute myocarditis, unspecified
0.308 0.692 0.000
I42.5 Other restrictive cardiomyopathy
0.307 0.693 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.307 0.693 0.000
F33.8 Other recurrent depressive disorders
0.000 0.693 0.307
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.694 0.306
I07 Rheumatic tricuspid valve diseases
0.306 0.694 0.000
F30.0 Hypomania
0.000 0.694 0.306
I35.2 Aortic (valve) stenosis with insufficiency
0.305 0.695 0.000
I22.8 Subsequent myocardial infarction of other sites
0.302 0.698 0.000
F39 Unspecified mood [affective] disorder
0.000 0.698 0.301
I20.1 Angina pectoris with documented spasm
0.301 0.699 0.000
I70.1 Atherosclerosis of renal artery
0.299 0.700 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.299 0.701 0.000
I51.8 Other ill-defined heart diseases
0.299 0.701 0.000
I28 Other diseases of pulmonary vessels
0.297 0.703 0.000
I72.9 Aneurysm of unspecified site
0.294 0.705 0.000
F30.8 Other manic episodes
0.000 0.709 0.291
I73.1 Thromboangiitis obliterans [Buerger]
0.289 0.710 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.283 0.717 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.283 0.717 0.000
I98.0 Cardiovascular syphilis
0.283 0.717 0.000
I42.6 Alcoholic cardiomyopathy
0.283 0.717 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.282 0.718 0.000
F32.8 Other depressive episodes
0.000 0.724 0.276
I42.2 Other hypertrophic cardiomyopathy
0.276 0.724 0.000
I27 Other pulmonary heart diseases
0.275 0.725 0.000
I73.8 Other specified peripheral vascular diseases
0.272 0.728 0.000
I08.8 Other multiple valve diseases
0.270 0.730 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.270 0.730 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.269 0.731 0.000
I79.1 Aortitis in diseases classified elsewhere
0.267 0.733 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.267 0.733 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.733 0.266
I35.9 Aortic valve disorder, unspecified
0.266 0.734 0.000
I70.9 Generalised and unspecified atherosclerosis
0.265 0.735 0.000
I05.9 Mitral valve disease, unspecified
0.265 0.735 0.000
F30.1 Mania without psychotic symptoms
0.000 0.736 0.264
I30 Acute pericarditis
0.262 0.737 0.000
I06.0 Rheumatic aortic stenosis
0.261 0.739 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.259 0.740 0.000
I46.9 Cardiac arrest, unspecified
0.258 0.742 0.000
F32.1 Moderate depressive episode
0.000 0.745 0.255
F34.0 Cyclothymia
0.000 0.746 0.254
I08.1 Disorders of both mitral and tricuspid valves
0.252 0.748 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.000 0.748 0.252
I74.9 Embolism and thrombosis of unspecified artery
0.252 0.748 0.000
I51.6 Cardiovascular disease, unspecified
0.251 0.749 0.000
I70.8 Atherosclerosis of other arteries
0.251 0.749 0.000
I05.0 Mitral stenosis
0.248 0.751 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.243 0.757 0.000
I50.9 Heart failure, unspecified
0.242 0.758 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.241 0.759 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.240 0.759 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.240 0.759 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.240 0.759 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.240 0.759 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.239 0.760 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.239 0.761 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.239 0.761 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.235 0.765 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.000 0.765 0.235
F34.8 Other persistent mood [affective] disorders
0.000 0.765 0.235
I74.5 Embolism and thrombosis of iliac artery
0.232 0.768 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.231 0.769 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.230 0.770 0.000
F38.1 Other recurrent mood [affective] disorders
0.000 0.770 0.230
I72.6 Aneurysm and dissection of vertebral artery
0.229 0.770 0.000
I33.9 Acute endocarditis, unspecified
0.227 0.773 0.000
F38.8 Other specified mood [affective] disorders
0.000 0.778 0.222
F38.0 Other single mood [affective] disorders
0.000 0.778 0.222
I70.0 Atherosclerosis of aorta
0.221 0.779 0.000
I05.8 Other mitral valve diseases
0.221 0.779 0.000
I07.9 Tricuspid valve disease, unspecified
0.219 0.780 0.000
I07.8 Other tricuspid valve diseases
0.219 0.780 0.000
I07.2 Tricuspid stenosis with insufficiency
0.219 0.780 0.000
I07.0 Tricuspid stenosis
0.219 0.780 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.218 0.782 0.000
I27.0 Primary pulmonary hypertension
0.216 0.784 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.215 0.785 0.000
I28.1 Aneurysm of pulmonary artery
0.213 0.787 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.213 0.787 0.000
L05 Pilonidal cyst
0.015 0.787 0.198
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.212 0.787 0.000
I47.0 Reentry ventricular arrhythmia
0.211 0.788 0.001
I71.1 Thoracic aortic aneurysm, ruptured
0.211 0.789 0.000
I72.4 Aneurysm of artery of lower extremity
0.207 0.793 0.000
I72.2 Aneurysm of renal artery
0.205 0.794 0.000
L03.0 Cellulitis of finger and toe
0.000 0.795 0.205
I22.0 Subsequent myocardial infarction of anterior wall
0.203 0.797 0.000
I72.1 Aneurysm of artery of upper extremity
0.202 0.797 0.000
I05.1 Rheumatic mitral insufficiency
0.202 0.798 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.201 0.799 0.000
F34.1 Dysthymia
0.000 0.800 0.200
F60 Specific personality disorders
0.000 0.801 0.199
I27.1 Kyphoscoliotic heart disease
0.197 0.803 0.000
I72.0 Aneurysm of carotid artery
0.196 0.804 0.000
I26 Pulmonary embolism
0.195 0.805 0.000
F60-F69 Disorders of adult personality and behaviour
0.000 0.805 0.195
I27.9 Pulmonary heart disease, unspecified
0.193 0.807 0.000
I72.3 Aneurysm of iliac artery
0.192 0.808 0.000
F60.3 Emotionally unstable personality disorder
0.000 0.809 0.191
F60.9 Personality disorder, unspecified
0.000 0.809 0.191
I72.8 Aneurysm of other specified arteries
0.190 0.809 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.190 0.810 0.000
I27.8 Other specified pulmonary heart diseases
0.190 0.810 0.000
I30.8 Other forms of acute pericarditis
0.188 0.811 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.188 0.811 0.000
Chapter V Mental and behavioural disorders
0.000 0.812 0.188
I71.0 Dissection of aorta [any part]
0.186 0.814 0.000
I42.9 Cardiomyopathy, unspecified
0.185 0.815 0.000
I42.8 Other cardiomyopathies
0.181 0.819 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.180 0.820 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.823 0.177
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.176 0.824 0.000
K72.9 Hepatic failure, unspecified
0.000 0.824 0.176
K74.6 Other and unspecified cirrhosis of liver
0.000 0.825 0.175
K74 Fibrosis and cirrhosis of liver
0.000 0.826 0.174
I71.3 Abdominal aortic aneurysm, ruptured
0.171 0.829 0.000
K70-K77 Diseases of liver
0.000 0.832 0.168
F64 Gender identity disorders
0.000 0.833 0.166
I12.9 Hypertensive renal disease without renal failure
0.165 0.835 0.000
I28.8 Other specified diseases of pulmonary vessels
0.164 0.836 0.000
K72.0 Acute and subacute hepatic failure
0.000 0.838 0.162
I31 Other diseases of pericardium
0.161 0.839 0.000
F69 Unspecified disorder of adult personality and behaviour
0.000 0.840 0.160
K75 Other inflammatory liver diseases
0.000 0.840 0.160
I70.01 Atherosclerosis of aorta (with gangrene)
0.159 0.841 0.000
F60.6 Anxious [avoidant] personality disorder
0.000 0.841 0.159
K74.3 Primary biliary cirrhosis
0.000 0.843 0.157
I70.80 Atherosclerosis of other arteries (without gangrene)
0.151 0.848 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.149 0.851 0.000
I44.2 Atrioventricular block, complete
0.149 0.851 0.000
K72.1 Chronic hepatic failure
0.000 0.853 0.147
F64.0 Transsexualism
0.000 0.854 0.146
F60.0 Paranoid personality disorder
0.000 0.854 0.146
F60.7 Dependent personality disorder
0.000 0.854 0.146
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.144 0.856 0.000
F60.5 Anankastic personality disorder
0.000 0.857 0.143
F80-F89 Disorders of psychological development
0.000 0.857 0.143
F60.4 Histrionic personality disorder
0.000 0.857 0.143
F60.2 Dissocial personality disorder
0.000 0.857 0.143
F60.1 Schizoid personality disorder
0.000 0.857 0.143
K75.4 Autoimmune hepatitis
0.000 0.859 0.141
K75.0 Abscess of liver
0.000 0.860 0.140
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.000 0.860 0.140
F65 Disorders of sexual preference
0.000 0.860 0.140
F63 Habit and impulse disorders
0.000 0.860 0.140
K74.5 Biliary cirrhosis, unspecified
0.000 0.862 0.138
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.863 0.137
K73 Chronic hepatitis, not elsewhere classified
0.000 0.864 0.136
F68 Other disorders of adult personality and behaviour
0.000 0.864 0.136
I45 Other conduction disorders
0.136 0.864 0.000
I05.2 Mitral stenosis with insufficiency
0.135 0.864 0.001
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.864 0.136
I22.1 Subsequent myocardial infarction of inferior wall
0.135 0.865 0.000
I78 Diseases of capillaries
0.133 0.866 0.002
I27.2 Other secondary pulmonary hypertension
0.134 0.866 0.000
I12.0 Hypertensive renal disease with renal failure
0.132 0.868 0.000
F70-F79 Mental retardation
0.000 0.869 0.131
F62 Enduring personality changes, not attributable to brain damage and disease
0.000 0.869 0.131
F20 Schizophrenia
0.000 0.869 0.131
K75.9 Inflammatory liver disease, unspecified
0.000 0.870 0.130
F60.8 Other specific personality disorders
0.000 0.871 0.129
I50.0 Congestive heart failure
0.129 0.871 0.000
F20.0 Paranoid schizophrenia
0.000 0.872 0.128
I30.1 Infective pericarditis
0.125 0.874 0.001
K74.4 Secondary biliary cirrhosis
0.000 0.875 0.125
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.875 0.125
F81 Specific developmental disorders of scholastic skills
0.000 0.877 0.123
F61 Mixed and other personality disorders
0.000 0.878 0.121
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.879 0.121
K74.1 Hepatic sclerosis
0.000 0.879 0.120
K74.0 Hepatic fibrosis
0.000 0.880 0.120
F64.9 Gender identity disorder, unspecified
0.000 0.880 0.119
F64.8 Other gender identity disorders
0.000 0.880 0.119
F64.2 Gender identity disorder of childhood
0.000 0.880 0.119
F64.1 Dual-role transvestism
0.000 0.880 0.119
K77 Liver disorders in diseases classified elsewhere
0.000 0.882 0.118
I31.8 Other specified diseases of pericardium
0.116 0.884 0.000
I31.2 Haemopericardium, not elsewhere classified
0.116 0.884 0.000
K75.2 Nonspecific reactive hepatitis
0.000 0.885 0.115
K75.1 Phlebitis of portal vein
0.000 0.885 0.115
I45.4 Nonspecific intraventricular block
0.114 0.886 0.000
F99-F99 Unspecified mental disorder
0.000 0.889 0.111
I30.9 Acute pericarditis, unspecified
0.110 0.890 0.000
I45.2 Bifascicular block
0.109 0.891 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.109 0.891 0.000
F81.9 Developmental disorder of scholastic skills, unspecified
0.000 0.892 0.108
K73.9 Chronic hepatitis, unspecified
0.000 0.892 0.108
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.106 0.893 0.001
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.893 0.107
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.896 0.104
F89 Unspecified disorder of psychological development
0.000 0.897 0.103
F88 Other disorders of psychological development
0.000 0.897 0.103
F83 Mixed specific developmental disorders
0.000 0.897 0.103
F82 Specific developmental disorder of motor function
0.000 0.897 0.103
I45.0 Right fascicular block
0.102 0.898 0.000
K71 Toxic liver disease
0.000 0.898 0.101
I70.00 Atherosclerosis of aorta (without gangrene)
0.101 0.899 0.000
F63.9 Habit and impulse disorder, unspecified
0.000 0.900 0.100
F63.8 Other habit and impulse disorders
0.000 0.900 0.100
F63.3 Trichotillomania
0.000 0.900 0.100
F63.2 Pathological stealing [kleptomania]
0.000 0.900 0.100
F63.1 Pathological fire-setting [pyromania]
0.000 0.900 0.100
F63.0 Pathological gambling
0.000 0.900 0.100
F65.9 Disorder of sexual preference, unspecified
0.000 0.900 0.100
F65.8 Other disorders of sexual preference
0.000 0.900 0.100
F65.6 Multiple disorders of sexual preference
0.000 0.900 0.100
F65.5 Sadomasochism
0.000 0.900 0.100
F65.4 Paedophilia
0.000 0.900 0.100
F65.3 Voyeurism
0.000 0.900 0.100
F65.2 Exhibitionism
0.000 0.900 0.100
F65.1 Fetishistic transvestism
0.000 0.900 0.100
F65.0 Fetishism
0.000 0.900 0.100
F66.9 Psychosexual development disorder, unspecified
0.000 0.900 0.100
F66.8 Other psychosexual development disorders
0.000 0.900 0.100
F66.2 Sexual relationship disorder
0.000 0.900 0.100
F66.1 Egodystonic sexual orientation
0.000 0.900 0.100
F66.0 Sexual maturation disorder
0.000 0.900 0.100
F22 Persistent delusional disorders
0.000 0.900 0.100
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.900 0.100
F84 Pervasive developmental disorders
0.000 0.901 0.099
I78.8 Other diseases of capillaries
0.098 0.901 0.001
I77 Other disorders of arteries and arterioles
0.098 0.902 0.000
F28 Other nonorganic psychotic disorders
0.000 0.902 0.098
F24 Induced delusional disorder
0.000 0.902 0.098
F21 Schizotypal disorder
0.000 0.902 0.098
F20.5 Residual schizophrenia
0.000 0.902 0.098
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.902 0.098
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.902 0.098
F68.8 Other specified disorders of adult personality and behaviour
0.000 0.902 0.098
F68.0 Elaboration of physical symptoms for psychological reasons
0.000 0.902 0.098
I31.3 Pericardial effusion (noninflammatory)
0.096 0.904 0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]
0.000 0.905 0.094
F78 Other mental retardation
0.000 0.906 0.094
F73 Profound mental retardation
0.000 0.906 0.094
F72 Severe mental retardation
0.000 0.906 0.094
F71 Moderate mental retardation
0.000 0.906 0.094

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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