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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7316650
log Bayes Factor = 10.7172
Chromosome 12   position 112,439,664  (GRCh37) Explore rs7316650 on Ensembl!
Variant rs7316650 is part of Cluster X0112

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.009 0.991
I25.2 Old myocardial infarction
0.000 0.013 0.987
I21.9 Acute myocardial infarction, unspecified
0.000 0.021 0.979
I22 Subsequent myocardial infarction
0.000 0.067 0.933
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.088 0.912
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.094 0.906
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.099 0.901
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.103 0.897
Z95.4 Presence of other heart-valve replacement
0.000 0.109 0.891
Chapter IX Diseases of the circulatory system
0.000 0.141 0.859
Z95.3 Presence of xenogenic heart valve
0.000 0.144 0.856
I21.4 Acute subendocardial myocardial infarction
0.000 0.145 0.855
I10-I15 Hypertensive diseases
0.000 0.151 0.849
I10 Essential (primary) hypertension
0.000 0.158 0.842
I25.5 Ischaemic cardiomyopathy
0.000 0.158 0.842
Z95.1 Presence of aortocoronary bypass graft
0.000 0.173 0.827
I05-I09 Chronic rheumatic heart diseases
0.000 0.186 0.814
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.187 0.813
I73 Other peripheral vascular diseases
0.000 0.203 0.797
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.207 0.793
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.221 0.779
I73.0 Raynaud's syndrome
0.000 0.239 0.761
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.250 0.750
I24 Other acute ischaemic heart diseases
0.000 0.258 0.742
I08 Multiple valve diseases
0.000 0.259 0.741
I73.9 Peripheral vascular disease, unspecified
0.000 0.276 0.724
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.277 0.723
I12 Hypertensive renal disease
0.000 0.280 0.720
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I05 Rheumatic mitral valve diseases
0.000 0.284 0.716
Z95.2 Presence of prosthetic heart valve
0.000 0.293 0.707
I20 Angina pectoris
0.000 0.310 0.690
I12.9 Hypertensive renal disease without renal failure
0.000 0.318 0.682
I08.0 Disorders of both mitral and aortic valves
0.000 0.329 0.671
I25.4 Coronary artery aneurysm
0.000 0.337 0.663
I20.9 Angina pectoris, unspecified
0.000 0.338 0.662
I25.3 Aneurysm of heart
0.000 0.350 0.650
I22.8 Subsequent myocardial infarction of other sites
0.000 0.353 0.647
I23 Certain current complications following acute myocardial infarction
0.000 0.353 0.647
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.370 0.630
I71 Aortic aneurysm and dissection
0.000 0.370 0.629
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.372 0.628
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.376 0.624
I07 Rheumatic tricuspid valve diseases
0.000 0.382 0.618
I00-I02 Acute rheumatic fever
0.000 0.384 0.616
I74 Arterial embolism and thrombosis
0.000 0.387 0.613
I13 Hypertensive heart and renal disease
0.000 0.391 0.609
I05.0 Mitral stenosis
0.000 0.393 0.607
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.396 0.604
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.398 0.602
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.399 0.601
I78 Diseases of capillaries
0.000 0.399 0.601
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.400 0.600
I06 Rheumatic aortic valve diseases
0.000 0.417 0.583
I05.2 Mitral stenosis with insufficiency
0.000 0.421 0.579
I73.8 Other specified peripheral vascular diseases
0.000 0.428 0.571
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.428 0.571
I72 Other aneurysm
0.000 0.433 0.566
I24.8 Other forms of acute ischaemic heart disease
0.000 0.435 0.565
I15 Secondary hypertension
0.000 0.459 0.541
I24.1 Dressler's syndrome
0.000 0.468 0.532
I08.9 Multiple valve disease, unspecified
0.000 0.469 0.531
I05.1 Rheumatic mitral insufficiency
0.000 0.470 0.530
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.471 0.529
I11 Hypertensive heart disease
0.000 0.471 0.529
I09 Other rheumatic heart diseases
0.000 0.473 0.527
I70 Atherosclerosis
0.000 0.475 0.525
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.478 0.522
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.486 0.514
I05.8 Other mitral valve diseases
0.000 0.487 0.513
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.490 0.510
I05.9 Mitral valve disease, unspecified
0.000 0.494 0.506
I74.5 Embolism and thrombosis of iliac artery
0.000 0.496 0.504
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.504 0.496
I07.1 Tricuspid insufficiency
0.000 0.523 0.477
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.523 0.477
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.533 0.467
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.536 0.464
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.536 0.464
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.536 0.464
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.549 0.451
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.549 0.451
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.549 0.451
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.549 0.451
Z95.0 Presence of cardiac pacemaker
0.000 0.552 0.448
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.553 0.447
I07.9 Tricuspid valve disease, unspecified
0.000 0.557 0.443
I07.8 Other tricuspid valve diseases
0.000 0.557 0.443
I07.2 Tricuspid stenosis with insufficiency
0.000 0.557 0.443
I07.0 Tricuspid stenosis
0.000 0.557 0.443
I02 Rheumatic chorea
0.000 0.558 0.442
I01 Rheumatic fever with heart involvement
0.000 0.558 0.442
I00 Rheumatic fever without mention of heart involvement
0.000 0.558 0.442
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.561 0.439
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.561 0.439
I08.8 Other multiple valve diseases
0.000 0.561 0.439
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.563 0.437
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.563 0.437
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.563 0.437
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.563 0.437
I78.9 Disease of capillaries, unspecified
0.000 0.569 0.431
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.570 0.430
I79.1 Aortitis in diseases classified elsewhere
0.000 0.570 0.430
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.570 0.430
I78.8 Other diseases of capillaries
0.000 0.572 0.428
I72.8 Aneurysm of other specified arteries
0.000 0.577 0.423
I72.3 Aneurysm of iliac artery
0.000 0.579 0.421
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.582 0.418
I06.8 Other rheumatic aortic valve diseases
0.000 0.582 0.418
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.582 0.418
I06.1 Rheumatic aortic insufficiency
0.000 0.582 0.418
I06.0 Rheumatic aortic stenosis
0.000 0.582 0.418
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.591 0.409
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.591 0.409
I72.9 Aneurysm of unspecified site
0.000 0.594 0.406
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.594 0.406
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.594 0.406
I72.2 Aneurysm of renal artery
0.000 0.594 0.406
I72.1 Aneurysm of artery of upper extremity
0.000 0.594 0.406
I20.1 Angina pectoris with documented spasm
0.000 0.604 0.395
I23.8 Other current complications following acute myocardial infarction
0.000 0.606 0.394
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.608 0.392
I72.4 Aneurysm of artery of lower extremity
0.000 0.609 0.391
I70.0 Atherosclerosis of aorta
0.000 0.610 0.390
I15.9 Seconday hypertension, unspecified
0.000 0.612 0.388
I15.8 Other secondary hypertension
0.000 0.612 0.388
I15.2 Hypertension secondary to endocrine disorders
0.000 0.612 0.388
I15.0 Renovascular hypertension
0.000 0.612 0.388
I09.8 Other specified rheumatic heart diseases
0.000 0.622 0.378
I09.2 Chronic rheumatic pericarditis
0.000 0.622 0.378
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.622 0.378
I09.0 Rheumatic myocarditis
0.000 0.622 0.378
I70.1 Atherosclerosis of renal artery
0.000 0.623 0.377
I70.9 Generalised and unspecified atherosclerosis
0.000 0.623 0.376
I70.8 Atherosclerosis of other arteries
0.000 0.623 0.376
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.626 0.374
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.626 0.374
I74.8 Embolism and thrombosis of other arteries
0.000 0.629 0.371
I72.0 Aneurysm of carotid artery
0.000 0.632 0.368
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.635 0.364
I99 Other and unspecified disorders of circulatory system
0.000 0.645 0.355
I97.1 Other functional disturbances following cardiac surgery
0.000 0.672 0.327
I30-I52 Other forms of heart disease
0.000 0.673 0.327
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.677 0.323
I09.9 Rheumatic heart disease, unspecified
0.000 0.679 0.321
I15.1 Hypertension secondary to other renal disorders
0.000 0.679 0.320
I20.8 Other forms of angina pectoris
0.000 0.681 0.319
I78.1 Naevus, nonneoplastic
0.000 0.681 0.319
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.683 0.317
I01.8 Other acute rheumatic heart disease
0.000 0.683 0.317
I01.2 Acute rheumatic myocarditis
0.000 0.683 0.317
I01.1 Acute rheumatic endocarditis
0.000 0.683 0.317
I01.0 Acute rheumatic pericarditis
0.000 0.683 0.317
I02.9 Rheumatic chorea without heart involvement
0.000 0.683 0.317
I02.0 Rheumatic chorea with heart involvement
0.000 0.683 0.317
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.685 0.315
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.690 0.310
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.690 0.309
I35 Nonrheumatic aortic valve disorders
0.000 0.692 0.308
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.693 0.307
I35.0 Aortic (valve) stenosis
0.000 0.702 0.298
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.703 0.297
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.706 0.294
I44 Atrioventricular and left bundle-branch block
0.000 0.715 0.285
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.718 0.281
I97.0 Postcardiotomy syndrome
0.000 0.718 0.281
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.720 0.280
I36 Nonrheumatic tricuspid valve disorders
0.000 0.720 0.280
I71.0 Dissection of aorta [any part]
0.001 0.724 0.275
I42 Cardiomyopathy
0.000 0.724 0.276
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.729 0.270
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.730 0.270
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.730 0.270
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.730 0.270
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.730 0.270
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.730 0.270
I47 Paroxysmal tachycardia
0.000 0.730 0.270
I49 Other cardiac arrhythmias
0.000 0.731 0.269
I44.7 Left bundle-branch block, unspecified
0.000 0.739 0.261
I49.3 Ventricular premature depolarisation
0.000 0.740 0.260
I47.2 Ventricular tachycardia
0.000 0.745 0.255
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.747 0.253
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.754 0.246
I35.9 Aortic valve disorder, unspecified
0.000 0.755 0.245
I49.4 Other and unspecified premature depolarisation
0.000 0.755 0.245
I37 Pulmonary valve disorders
0.000 0.759 0.241
I42.0 Dilated cardiomyopathy
0.000 0.764 0.236
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.764 0.236
I52 Other heart disorders in diseases classified elsewhere
0.000 0.765 0.235
I48 Atrial fibrillation and flutter
0.000 0.765 0.235
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.765 0.235
I41 Myocarditis in diseases classified elsewhere
0.000 0.765 0.235
I40 Acute myocarditis
0.000 0.765 0.235
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.765 0.235
I32 Pericarditis in diseases classified elsewhere
0.000 0.765 0.235
I44.6 Other and unspecified fascicular block
0.000 0.766 0.234
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.768 0.232
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.768 0.232
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.768 0.232
I98.0 Cardiovascular syphilis
0.000 0.768 0.232
I42.9 Cardiomyopathy, unspecified
0.000 0.772 0.228
I12.0 Hypertensive renal disease with renal failure
0.000 0.773 0.227
I77 Other disorders of arteries and arterioles
0.000 0.777 0.223
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.781 0.219
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.783 0.217
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.787 0.213
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.787 0.213
I28 Other diseases of pulmonary vessels
0.000 0.788 0.212
I49.0 Ventricular fibrillation and flutter
0.000 0.788 0.212
I35.8 Other aortic valve disorders
0.000 0.792 0.208
I44.5 Left posterior fascicular block
0.000 0.795 0.205
I44.4 Left anterior fascicular block
0.000 0.795 0.205
I44.3 Other and unspecified atrioventricular block
0.000 0.796 0.204
I47.0 Reentry ventricular arrhythmia
0.000 0.797 0.203
I44.1 Atrioventricular block, second degree
0.000 0.797 0.203
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.799 0.201
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.799 0.201
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.799 0.201
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.799 0.201
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.802 0.198
I42.5 Other restrictive cardiomyopathy
0.000 0.802 0.198
I42.4 Endocardial fibroelastosis
0.000 0.802 0.198
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.802 0.198
I33 Acute and subacute endocarditis
0.000 0.805 0.195
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.805 0.195
I49.2 Junctional premature depolarisation
0.000 0.807 0.193
I44.0 Atrioventricular block, first degree
0.000 0.808 0.192
I50 Heart failure
0.000 0.809 0.191
I42.6 Alcoholic cardiomyopathy
0.000 0.820 0.180
I37.1 Pulmonary valve insufficiency
0.000 0.820 0.179
I30 Acute pericarditis
0.000 0.821 0.178
I42.2 Other hypertrophic cardiomyopathy
0.000 0.824 0.176
I35.1 Aortic (valve) insufficiency
0.000 0.824 0.175
I37.9 Pulmonary valve disorder, unspecified
0.000 0.827 0.173
I37.8 Other pulmonary valve disorders
0.000 0.827 0.173
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.827 0.173
I37.0 Pulmonary valve stenosis
0.000 0.827 0.173
I42.8 Other cardiomyopathies
0.000 0.828 0.172
I26 Pulmonary embolism
0.000 0.829 0.171
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.831 0.168
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.831 0.168
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.831 0.168
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.831 0.168
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.831 0.168
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.831 0.168
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.831 0.168
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.831 0.168
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.831 0.168
I40.9 Acute myocarditis, unspecified
0.000 0.831 0.168
I40.8 Other acute myocarditis
0.000 0.831 0.168
I40.1 Isolated myocarditis
0.000 0.831 0.168
I40.0 Infective myocarditis
0.000 0.831 0.168
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.831 0.168
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.831 0.168
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.831 0.168
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.831 0.168
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.831 0.168
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.831 0.168
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.831 0.168
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.831 0.168
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.831 0.168
I48.4 Atypical atrial flutter
0.000 0.831 0.168
I48.3 Typical atrial flutter
0.000 0.831 0.168
I48.2 Chronic atrial fibrillation
0.000 0.831 0.168
I48.1 Persistent atrial fibrillation
0.000 0.831 0.168
I48.0 Paroxysmal atrial fibrillation
0.000 0.831 0.168
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.831 0.168
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.831 0.168
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.831 0.168
I77.6 Arteritis, unspecified
0.000 0.833 0.167
I77.5 Necrosis of artery
0.000 0.840 0.160
I77.4 Coeliac artery compression syndrome
0.000 0.840 0.160
I77.3 Arterial fibromuscular dysplasia
0.000 0.840 0.160
I77.2 Rupture of artery
0.000 0.840 0.160
I44.2 Atrioventricular block, complete
0.000 0.842 0.158
I38 Endocarditis, valve unspecified
0.000 0.844 0.156
I20.0 Unstable angina
0.000 0.844 0.156
I49.1 Atrial premature depolarisation
0.000 0.845 0.155
I31 Other diseases of pericardium
0.000 0.847 0.153
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.847 0.152
I28.1 Aneurysm of pulmonary artery
0.000 0.847 0.152
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.847 0.152
I50.0 Congestive heart failure
0.000 0.850 0.150
I46 Cardiac arrest
0.000 0.860 0.140
I33.9 Acute endocarditis, unspecified
0.000 0.860 0.140
I28.8 Other specified diseases of pulmonary vessels
0.000 0.861 0.138
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.866 0.134
I49.9 Cardiac arrhythmia, unspecified
0.000 0.868 0.132
I77.0 Arteriovenous fistula, acquired
0.000 0.869 0.131
I30.8 Other forms of acute pericarditis
0.000 0.872 0.128
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.872 0.128
I30.1 Infective pericarditis
0.000 0.873 0.127
I77.1 Stricture of artery
0.000 0.875 0.125
M22 Disorders of patella
0.125 0.875 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.877 0.123
M20-M25 Other joint disorders
0.123 0.877 0.000
M24 Other specific joint derangements
0.123 0.877 0.000
M22.4 Chondromalacia patellae
0.123 0.877 0.000
I51 Complications and ill-defined descriptions of heart disease
0.000 0.879 0.121
I50.1 Left ventricular failure
0.000 0.882 0.118
M24.2 Disorder of ligament
0.118 0.882 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.883 0.117
M25 Other joint disorders, not elsewhere classified
0.116 0.884 0.000
M24.0 Loose body in joint
0.115 0.885 0.000
I77.8 Other specified disorders of arteries and arterioles
0.000 0.887 0.113
M20 Acquired deformities of fingers and toes
0.112 0.888 0.000
M24.23 Disorder of ligament (Forearm)
0.111 0.889 0.000
I31.8 Other specified diseases of pericardium
0.000 0.890 0.110
I31.2 Haemopericardium, not elsewhere classified
0.000 0.890 0.110
I31.1 Chronic constrictive pericarditis
0.000 0.890 0.110
I31.0 Chronic adhesive pericarditis
0.000 0.890 0.110
M20.0 Deformity of finger(s)
0.107 0.893 0.000
I27 Other pulmonary heart diseases
0.000 0.893 0.106
I85 Oesophageal varices
0.000 0.894 0.106
M22.3 Other derangements of patella
0.106 0.894 0.000
M25.3 Other instability of joint
0.106 0.894 0.000
M25.0 Haemarthrosis
0.103 0.896 0.000
M24.02 Loose body in joint (Upper arm)
0.103 0.897 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.897 0.103
I33.0 Acute and subacute infective endocarditis
0.000 0.899 0.101
I46.1 Sudden cardiac death, so described
0.000 0.899 0.101
M24.8 Other specific joint derangements, not elsewhere classified
0.100 0.900 0.000
M20.5 Other deformities of toe(s) (acquired)
0.100 0.900 0.000
M21 Other acquired deformities of limbs
0.099 0.901 0.000
I50.9 Heart failure, unspecified
0.000 0.902 0.098
I85.0 Oesophageal varices with bleeding
0.000 0.902 0.098
M22.8 Other disorders of patella
0.098 0.902 0.000
M34 Systemic sclerosis
0.098 0.902 0.000
I51.9 Heart disease, unspecified
0.000 0.903 0.097
M25.4 Effusion of joint
0.097 0.903 0.000
M25.8 Other specified joint disorders
0.096 0.904 0.000
M31 Other necrotising vasculopathies
0.096 0.904 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.095 0.905 0.000
I51.4 Myocarditis, unspecified
0.000 0.905 0.095
M25.06 Haemarthrosis (Lower leg)
0.095 0.905 0.000
I45 Other conduction disorders
0.000 0.906 0.094
I31.3 Pericardial effusion (noninflammatory)
0.000 0.906 0.094
M22.2 Patellofemoral disorders
0.093 0.907 0.000
I86 Varicose veins of other sites
0.000 0.907 0.093
M24.07 Loose body in joint (Ankle and foot)
0.092 0.908 0.000
M25.31 Other instability of joint (Shoulder region)
0.092 0.908 0.000
M24.26 Disorder of ligament (Lower leg)
0.091 0.909 0.000
M24.03 Loose body in joint (Forearm)
0.091 0.909 0.000
M24.28 Disorder of ligament (Other)
0.091 0.909 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.090 0.910 0.000
M22.1 Recurrent subluxation of patella
0.090 0.910 0.000
M22.9 Disorder of patella, unspecified
0.090 0.910 0.000
M22.0 Recurrent dislocation of patella
0.090 0.910 0.000
I88 Nonspecific lymphadenitis
0.000 0.910 0.089
M24.21 Disorder of ligament (Shoulder region)
0.089 0.910 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.089 0.911 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.088 0.912 0.000
M24.9 Joint derangement, unspecified
0.088 0.912 0.000
M24.7 Protrusio acetabuli
0.088 0.912 0.000
M24.6 Ankylosis of joint
0.088 0.912 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.912 0.088
M24.5 Contracture of joint
0.087 0.913 0.000
M25.42 Effusion of joint (Upper arm)
0.087 0.913 0.000
I51.5 Myocardial degeneration
0.000 0.913 0.087
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.913 0.087
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.913 0.087
M25.9 Joint disorder, unspecified
0.087 0.913 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.914 0.086
M33 Dermatopolymyositis
0.086 0.914 0.000
I49.5 Sick sinus syndrome
0.000 0.914 0.085
M24.01 Loose body in joint (Shoulder region)
0.086 0.914 0.000
M25.36 Other instability of joint (Lower leg)
0.086 0.914 0.000
M32 Systemic lupus erythematosus
0.085 0.915 0.000
M24.29 Disorder of ligament (Site unspecified)
0.084 0.915 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.084 0.915 0.000
M24.22 Disorder of ligament (Upper arm)
0.084 0.915 0.000
M24.20 Disorder of ligament (Multiple sites)
0.084 0.915 0.000
M31.6 Other giant cell arteritis
0.084 0.916 0.000
M25.37 Other instability of joint (Ankle and foot)
0.084 0.916 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.084 0.916 0.000
M25.88 Other specified joint disorders (Other)
0.083 0.917 0.000
M25.2 Flail joint
0.083 0.917 0.000
M25.1 Fistula of joint
0.083 0.917 0.000
M24.09 Loose body in joint (Site unspecified)
0.083 0.917 0.000
M24.08 Loose body in joint (Other)
0.083 0.917 0.000
M24.06 Loose body in joint-Lower leg
0.083 0.917 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.083 0.917 0.000
M24.04 Loose body in joint (Hand)
0.083 0.917 0.000
M24.00 Loose body in joint (Multiple sites)
0.083 0.917 0.000
I27.8 Other specified pulmonary heart diseases
0.000 0.918 0.081
I86.4 Gastric varices
0.000 0.919 0.081
I49.8 Other specified cardiac arrhythmias
0.001 0.920 0.080
M24.24 Disorder of ligament (Hand)
0.080 0.920 0.000
I51.0 Cardiac septal defect, acquired
0.000 0.920 0.080
M21.0 Valgus deformity, not elsewhere classified
0.079 0.921 0.000
M34.9 Systemic sclerosis, unspecified
0.079 0.921 0.000
I85.9 Oesophageal varices without bleeding
0.000 0.921 0.079
M21.7 Unequal limb length (acquired)
0.079 0.921 0.000
M30 Polyarteritis nodosa and related conditions
0.078 0.922 0.000
M25.34 Other instability of joint (Hand)
0.078 0.922 0.000
M21.6 Other acquired deformities of ankle and foot
0.078 0.922 0.000
M20.2 Hallux rigidus
0.077 0.923 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.923 0.077
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.077 0.923 0.000
I27.1 Kyphoscoliotic heart disease
0.000 0.923 0.076
M25.39 Other instability of joint (Site unspecified)
0.076 0.924 0.000
M25.38 Other instability of joint (Other)
0.076 0.924 0.000
M25.35 Other instability of joint (Pelvic region and thigh)
0.076 0.924 0.000
M25.33 Other instability of joint (Forearm)
0.076 0.924 0.000
M25.32 Other instability of joint (Upper arm)
0.076 0.924 0.000
M25.30 Other instability of joint (Multiple sites)
0.076 0.924 0.000
M21.3 Wrist or foot drop (acquired)
0.076 0.924 0.000
I87 Other disorders of veins
0.000 0.924 0.076
M25.7 Osteophyte
0.076 0.924 0.000
I45.9 Conduction disorder, unspecified
0.000 0.924 0.076
M24.1 Other articular cartilage disorders
0.076 0.924 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.075 0.924 0.000
I30.9 Acute pericarditis, unspecified
0.001 0.925 0.075
M25.09 Haemarthrosis (Site unspecified)
0.074 0.926 0.000
M25.08 Haemarthrosis (Other)
0.074 0.926 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.074 0.926 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.074 0.926 0.000
M25.04 Haemarthrosis (Hand)
0.074 0.926 0.000
M25.03 Haemarthrosis (Forearm)
0.074 0.926 0.000
M25.02 Haemarthrosis (Upper arm)
0.074 0.926 0.000
M25.01 Haemarthrosis (Shoulder region)
0.074 0.926 0.000
M25.00 Haemarthrosis (Multiple sites)
0.074 0.926 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.074 0.926 0.000
M25.86 Other specified joint disorders (Lower leg)
0.074 0.926 0.000
I60-I69 Cerebrovascular diseases
0.000 0.926 0.073
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.073 0.927 0.000
M34.8 Other forms of systemic sclerosis
0.072 0.927 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.072 0.928 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.072 0.928 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.072 0.928 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.072 0.928 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.072 0.928 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.072 0.928 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.072 0.928 0.000
M21.9 Acquired deformity of limb, unspecified
0.071 0.929 0.000
M21.8 Other specified acquired deformities of limbs
0.071 0.929 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.071 0.929 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.070 0.930 0.000
M34.0 Progressive systemic sclerosis
0.070 0.930 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.070 0.930 0.000
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.930 0.070
C71 Malignant neoplasm of brain
0.070 0.930 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.070 0.930 0.000
M25.49 Effusion of joint (Site unspecified)
0.070 0.930 0.000
M25.48 Effusion of joint (Other)
0.070 0.930 0.000
M25.44 Effusion of joint (Hand)
0.070 0.930 0.000
M25.43 Effusion of joint (Forearm)
0.070 0.930 0.000
M25.41 Effusion of joint (Shoulder region)
0.070 0.930 0.000
M25.40 Effusion of joint (Multiple sites)
0.070 0.930 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.069 0.931 0.000
M25.83 Other specified joint disorders (Forearm)
0.069 0.931 0.000
M25.82 Other specified joint disorders (Upper arm)
0.069 0.931 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.069 0.931 0.000
I46.9 Cardiac arrest, unspecified
0.000 0.931 0.069
M31.9 Necrotising vasculopathy, unspecified
0.069 0.931 0.000
M31.8 Other specified necrotising vasculopathies
0.069 0.931 0.000
M31.7 Microscopic polyangiitis
0.069 0.931 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.069 0.931 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.069 0.931 0.000
M31.2 Lethal midline granuloma
0.069 0.931 0.000
M31.1 Thrombotic microangiopathy
0.069 0.931 0.000
M31.0 Hypersensitivity angiitis
0.069 0.931 0.000
M21.4 Flat foot [pes planus] (acquired)
0.068 0.931 0.000
M25.84 Other specified joint disorders (Hand)
0.068 0.931 0.000
M34.1 CR(E)ST syndrome
0.068 0.932 0.000
I45.4 Nonspecific intraventricular block
0.000 0.932 0.068
I45.0 Right fascicular block
0.000 0.932 0.068
M21.2 Flexion deformity
0.068 0.932 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.932 0.068
M25.74 Osteophyte (Hand)
0.068 0.932 0.000
I45.5 Other specified heart block
0.000 0.933 0.067
I86.3 Vulval varices
0.000 0.933 0.067
I86.2 Pelvic varices
0.000 0.933 0.067
I86.0 Sublingual varices
0.000 0.933 0.067
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.066 0.933 0.000
I46.0 Cardiac arrest with successful resuscitation
0.000 0.934 0.066
I63 Cerebral infarction
0.000 0.934 0.066
C71.9 Brain, unspecified
0.066 0.934 0.000
M25.47 Effusion of joint (Ankle and foot)
0.066 0.934 0.000
M25.78 Osteophyte (Other)
0.066 0.934 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.065 0.934 0.000
M21.1 Varus deformity, not elsewhere classified
0.065 0.934 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.935 0.065
M25.72 Osteophyte (Upper arm)
0.065 0.935 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.065 0.935 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.065 0.935 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.065 0.935 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.065 0.935 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.065 0.935 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.065 0.935 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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