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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11065987
log Bayes Factor = 90.6309
Chromosome 12   position 112,072,424  (GRCh37) Explore rs11065987 on Ensembl!
Variant rs11065987 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
1.000 0.000 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
C77.3 Axillary and upper limb lymph nodes
0.000 0.000 1.000
Z95.2 Presence of prosthetic heart valve
1.000 0.000 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.000 1.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.000 1.000
Z95.4 Presence of other heart-valve replacement
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
0.999 0.001 0.000
I25.2 Old myocardial infarction
0.999 0.001 0.000
E03 Other hypothyroidism
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.998 0.002 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.002 0.998
I20 Angina pectoris
0.998 0.002 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.997 0.003 0.000
I20.9 Angina pectoris, unspecified
0.997 0.003 0.000
C78.7 Secondary malignant neoplasm of liver
0.000 0.006 0.994
I70-I79 Diseases of arteries, arterioles and capillaries
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.990 0.010 0.000
E10-E14 Diabetes mellitus
0.990 0.010 0.000
C50 Malignant neoplasm of breast
0.000 0.012 0.988
C77.9 Lymph node, unspecified
0.000 0.018 0.982
C50.9 Breast, unspecified
0.000 0.020 0.980
E10.9 Without complications
0.980 0.020 0.000
I74 Arterial embolism and thrombosis
0.975 0.025 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.974 0.026 0.000
C50.8 Overlapping lesion of breast
0.000 0.026 0.974
C50.4 Upper-outer quadrant of breast
0.000 0.030 0.970
I25.5 Ischaemic cardiomyopathy
0.966 0.034 0.000
E05.9 Thyrotoxicosis, unspecified
0.962 0.038 0.000
C50.1 Central portion of breast
0.000 0.039 0.961
E10.4 With neurological complications
0.955 0.045 0.000
C50-C50 Malignant neoplasm of breast
0.000 0.047 0.953
E10.5 With peripheral circulatory complications
0.953 0.047 0.000
Z95.3 Presence of xenogenic heart valve
0.953 0.047 0.000
I22 Subsequent myocardial infarction
0.948 0.052 0.000
E10.1 With ketoacidosis
0.947 0.053 0.000
I73 Other peripheral vascular diseases
0.941 0.059 0.000
E10.3 With ophthalmic complications
0.934 0.066 0.000
I73.9 Peripheral vascular disease, unspecified
0.932 0.068 0.000
E06 Thyroiditis
0.931 0.069 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.929 0.071 0.000
Chapter II Neoplasms
0.000 0.072 0.928
I74.5 Embolism and thrombosis of iliac artery
0.928 0.072 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.913 0.087 0.000
I12 Hypertensive renal disease
0.912 0.088 0.000
C78.2 Secondary malignant neoplasm of pleura
0.000 0.091 0.909
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.000 0.092 0.908
E20-E35 Disorders of other endocrine glands
0.895 0.105 0.000
C50.0 Nipple and areola
0.000 0.106 0.894
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.000 0.107 0.893
E10.0 With coma
0.891 0.109 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.890 0.110 0.000
I23 Certain current complications following acute myocardial infarction
0.885 0.115 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.116 0.884
E05.0 Thyrotoxicosis with diffuse goitre
0.875 0.125 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.130 0.870
E10.2 With renal complications
0.867 0.133 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.140 0.860
C77.2 Intra-abdominal lymph nodes
0.000 0.144 0.856
I77 Other disorders of arteries and arterioles
0.856 0.144 0.000
C79 Secondary malignant neoplasm of other sites
0.000 0.146 0.854
I20.8 Other forms of angina pectoris
0.849 0.151 0.000
C77.4 Inguinal and lower limb lymph nodes
0.000 0.160 0.840
I12.0 Hypertensive renal disease with renal failure
0.833 0.167 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.824 0.176 0.000
I21.4 Acute subendocardial myocardial infarction
0.818 0.182 0.000
E27 Other disorders of adrenal gland
0.817 0.183 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.000 0.186 0.814
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.189 0.811
I77.6 Arteritis, unspecified
0.809 0.191 0.000
E06.3 Autoimmune thyroiditis
0.805 0.195 0.000
I25.4 Coronary artery aneurysm
0.805 0.195 0.000
I23.8 Other current complications following acute myocardial infarction
0.802 0.198 0.000
I15 Secondary hypertension
0.802 0.198 0.000
I13 Hypertensive heart and renal disease
0.799 0.201 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.207 0.793
C77.8 Lymph nodes of multiple regions
0.000 0.209 0.791
E06.9 Thyroiditis, unspecified
0.791 0.209 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.790 0.210 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.788 0.212 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.787 0.213 0.000
E20 Hypoparathyroidism
0.787 0.213 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.215 0.785
E23 Hypofunction and other disorders of pituitary gland
0.779 0.221 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.227 0.773
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.228 0.772
C79.8 Secondary malignant neoplasm of other specified sites
0.000 0.229 0.771
I05-I09 Chronic rheumatic heart diseases
0.770 0.230 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.230 0.770
E27.1 Primary adrenocortical insufficiency
0.769 0.231 0.000
E03.1 Congenital hypothyroidism without goitre
0.764 0.236 0.000
E50-E64 Other nutritional deficiencies
0.762 0.238 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.000 0.239 0.761
I74.9 Embolism and thrombosis of unspecified artery
0.761 0.239 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.000 0.243 0.757
E03.8 Other specified hypothyroidism
0.755 0.245 0.000
I25.6 Silent myocardial ischaemia
0.752 0.247 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.251 0.749
I21.3 Acute transmural myocardial infarction of unspecified site
0.747 0.253 0.000
C80 Malignant neoplasm without specification of site
0.000 0.267 0.733
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.732 0.268 0.000
C51-C58 Malignant neoplasms of female genital organs
0.000 0.268 0.732
C49.3 Connective and soft tissue of thorax
0.000 0.273 0.727
E06.1 Subacute thyroiditis
0.725 0.275 0.000
I22.8 Subsequent myocardial infarction of other sites
0.721 0.279 0.000
E10.8 With unspecified complications
0.719 0.281 0.000
C92 Myeloid leukaemia
0.000 0.281 0.719
I22.0 Subsequent myocardial infarction of anterior wall
0.719 0.281 0.000
C90.0 Multiple myeloma
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
E03.5 Myxoedema coma
0.716 0.284 0.000
E03.4 Atrophy of thyroid (acquired)
0.716 0.284 0.000
E03.3 Postinfectious hypothyroidism
0.716 0.284 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.716 0.284 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.716 0.284 0.000
E00 Congenital iodine-deficiency syndrome
0.716 0.284 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.711 0.289 0.000
I20.1 Angina pectoris with documented spasm
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.290 0.000
I12.9 Hypertensive renal disease without renal failure
0.705 0.295 0.000
C45 Mesothelioma
0.000 0.298 0.702
M06.9 Rheumatoid arthritis, unspecified
0.701 0.299 0.000
E27.2 Addisonian crisis
0.701 0.299 0.000
I25.3 Aneurysm of heart
0.700 0.300 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.700 0.300 0.000
E05.5 Thyroid crisis or storm
0.698 0.301 0.000
E05.4 Thyrotoxicosis factitia
0.698 0.301 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.698 0.301 0.000
I71 Aortic aneurysm and dissection
0.697 0.303 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.697 0.303 0.000
E27.8 Other specified disorders of adrenal gland
0.696 0.304 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.695 0.304 0.000
I05 Rheumatic mitral valve diseases
0.692 0.308 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.689 0.311 0.000
E06.5 Other chronic thyroiditis
0.686 0.314 0.000
C81 Hodgkin's disease
0.000 0.315 0.685
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.316 0.684
E20.9 Hypoparathyroidism, unspecified
0.682 0.318 0.000
C51 Malignant neoplasm of vulva
0.000 0.318 0.682
C49.9 Connective and soft tissue, unspecified
0.000 0.320 0.680
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.324 0.676
C55 Malignant neoplasm of uterus, part unspecified
0.000 0.326 0.674
E28 Ovarian dysfunction
0.671 0.329 0.000
E10.7 With multiple complications
0.671 0.329 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.671 0.329 0.000
E10.6 With other specified complications
0.670 0.330 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.000 0.330 0.670
E06.4 Drug-induced thyroiditis
0.667 0.332 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.667 0.332 0.000
E06.0 Acute thyroiditis
0.667 0.332 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.666 0.333 0.000
M06 Other rheumatoid arthritis
0.666 0.334 0.000
E31 Polyglandular dysfunction
0.666 0.334 0.000
C82.0 Small cleaved cell, follicular
0.000 0.335 0.665
C91 Lymphoid leukaemia
0.000 0.336 0.664
I73.8 Other specified peripheral vascular diseases
0.663 0.337 0.000
E61 Deficiency of other nutrient elements
0.662 0.338 0.000
E23.6 Other disorders of pituitary gland
0.662 0.338 0.000
E25 Adrenogenital disorders
0.661 0.339 0.000
I77.2 Rupture of artery
0.656 0.344 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.654 0.346 0.000
E34 Other endocrine disorders
0.652 0.348 0.000
C95 Leukaemia of unspecified cell type
0.000 0.349 0.651
I15.1 Hypertension secondary to other renal disorders
0.651 0.349 0.000
E23.0 Hypopituitarism
0.650 0.350 0.000
C51.9 Vulva, unspecified
0.000 0.351 0.649
E07 Other disorders of thyroid
0.648 0.352 0.000
E16 Other disorders of pancreatic internal secretion
0.647 0.353 0.000
C76.0 Head, face and neck
0.000 0.353 0.647
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.646 0.354 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.356 0.644
E35 Disorders of endocrine glands in diseases classified elsewhere
0.642 0.358 0.000
E32 Diseases of thymus
0.642 0.358 0.000
E30 Disorders of puberty, not elsewhere classified
0.642 0.358 0.000
I70 Atherosclerosis
0.641 0.359 0.000
C93 Monocytic leukaemia
0.000 0.359 0.641
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.634 0.365 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.634 0.365 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.634 0.365 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.634 0.365 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.634 0.365 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.634 0.365 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.634 0.365 0.000
E22 Hyperfunction of pituitary gland
0.634 0.366 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.366 0.634
C94 Other leukaemias of specified cell type
0.000 0.366 0.634
I77.1 Stricture of artery
0.633 0.367 0.000
C86 Other specified types of T/NK-cell lymphoma
0.000 0.368 0.631
C90.2 Plasmacytoma, extramedullary
0.000 0.369 0.631
E23.2 Diabetes insipidus
0.631 0.369 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.626 0.374 0.000
I00-I02 Acute rheumatic fever
0.624 0.375 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.000 0.376 0.624
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.000 0.376 0.624
C46 Kaposi's sarcoma
0.000 0.376 0.624
E20.1 Pseudohypoparathyroidism
0.623 0.377 0.000
C84.0 Mycosis fungoides
0.000 0.380 0.620
C49.5 Connective and soft tissue of pelvis
0.000 0.383 0.617
I05.2 Mitral stenosis with insufficiency
0.614 0.386 0.000
I77.5 Necrosis of artery
0.613 0.386 0.000
I77.4 Coeliac artery compression syndrome
0.613 0.386 0.000
I77.3 Arterial fibromuscular dysplasia
0.613 0.386 0.000
E40-E46 Malnutrition
0.613 0.387 0.000
M05-M14 Inflammatory polyarthropathies
0.612 0.388 0.000
I15.0 Renovascular hypertension
0.612 0.388 0.000
E13 Other specified diabetes mellitus
0.611 0.389 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.389 0.611
I73.1 Thromboangiitis obliterans [Buerger]
0.608 0.392 0.000
C92.0 Acute myeloid leukaemia
0.000 0.393 0.607
M06.4 Inflammatory polyarthropathy
0.606 0.394 0.000
C80.9 Malignant neoplasm, unspecified
0.000 0.400 0.600
I05.0 Mitral stenosis
0.600 0.400 0.000
I99 Other and unspecified disorders of circulatory system
0.598 0.402 0.000
E61.1 Iron deficiency
0.598 0.402 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.000 0.403 0.597
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.404 0.596
C81.0 Lymphocytic predominance
0.000 0.404 0.596
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.000 0.405 0.595
C84.5 Other and unspecified T-cell lymphomas
0.000 0.407 0.593
C15-C26 Malignant neoplasms of digestive organs
0.000 0.407 0.593
M05 Seropositive rheumatoid arthritis
0.591 0.409 0.000
C82.3 Follicular lymphoma grade IIIa
0.000 0.410 0.590
I07 Rheumatic tricuspid valve diseases
0.590 0.410 0.000
C49.6 Connective and soft tissue of trunk, unspecified
0.000 0.411 0.589
M07 Psoriatic and enteropathic arthropathies
0.589 0.411 0.000
I21.9 Acute myocardial infarction, unspecified
0.588 0.412 0.000
E58 Dietary calcium deficiency
0.587 0.413 0.000
E27.5 Adrenomedullary hyperfunction
0.586 0.414 0.000
E27.0 Other adrenocortical overactivity
0.586 0.414 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.415 0.585
C84.4 Peripheral T-cell lymphoma
0.000 0.415 0.585
C49.8 Overlapping lesion of connective and soft tissue
0.000 0.416 0.584
E26 Hyperaldosteronism
0.584 0.416 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.580 0.419 0.000
E16.2 Hypoglycaemia, unspecified
0.580 0.420 0.000
E51 Thiamine deficiency
0.575 0.424 0.000
I15.8 Other secondary hypertension
0.575 0.425 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.575 0.425 0.000
C92.9 Myeloid leukaemia, unspecified
0.000 0.426 0.574
I15.2 Hypertension secondary to endocrine disorders
0.574 0.426 0.000
M07.3 Other psoriatic arthropathies
0.573 0.427 0.000
E22.1 Hyperprolactinaemia
0.573 0.427 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.573 0.427 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.573 0.427 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.573 0.427 0.000
C49.4 Connective and soft tissue of abdomen
0.000 0.428 0.572
E05.8 Other thyrotoxicosis
0.572 0.428 0.000
C90.1 Plasma cell leukaemia
0.000 0.431 0.569
I77.8 Other specified disorders of arteries and arterioles
0.569 0.431 0.000
C81.2 Mixed cellularity
0.000 0.432 0.568
E15 Nondiabetic hypoglycaemic coma
0.566 0.433 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.566 0.434 0.000
E20.8 Other hypoparathyroidism
0.564 0.436 0.000
E20.0 Idiopathic hypoparathyroidism
0.564 0.436 0.000
C92.4 Acute promyelocytic leukaemia
0.000 0.436 0.564
C76.2 Abdomen
0.000 0.436 0.564
C76.8 Overlapping lesion of other and ill-defined sites
0.000 0.437 0.563
C76.7 Other ill-defined sites
0.000 0.437 0.563
C76.5 Lower limb
0.000 0.437 0.563
C76.4 Upper limb
0.000 0.437 0.563
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.563 0.437 0.000
I77.0 Arteriovenous fistula, acquired
0.563 0.437 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.563 0.437 0.000
I06 Rheumatic aortic valve diseases
0.560 0.439 0.000
C82.4 Follicular lymphoma grade IIIb
0.000 0.440 0.560
C76.3 Pelvis
0.000 0.440 0.559
E28.3 Primary ovarian failure
0.559 0.441 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.559 0.441 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.558 0.442 0.000
E23.1 Drug-induced hypopituitarism
0.558 0.442 0.000
C91.9 Lymphoid leukaemia, unspecified
0.000 0.445 0.555
C91.5 Adult T-cell leukaemia
0.000 0.446 0.554
C82.6 Cutaneous follicle centre lymphoma
0.000 0.448 0.552
C82.5 Diffuse follicle centre lymphoma
0.000 0.448 0.552
I35 Nonrheumatic aortic valve disorders
0.552 0.448 0.000
C45.7 Mesothelioma of other sites
0.000 0.449 0.551
I35.2 Aortic (valve) stenosis with insufficiency
0.551 0.449 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.451 0.549
C88 Malignant immunoproliferative diseases
0.000 0.451 0.549
I15.9 Seconday hypertension, unspecified
0.548 0.452 0.000
K90.0 Coeliac disease
0.548 0.452 0.000
C45.0 Mesothelioma of pleura
0.000 0.453 0.547
E64 Sequelae of malnutrition and other nutritional deficiencies
0.547 0.453 0.000
E63 Other nutritional deficiencies
0.547 0.453 0.000
E50 Vitamin A deficiency
0.547 0.453 0.000
E60 Dietary zinc deficiency
0.547 0.453 0.000
E59 Dietary selenium deficiency
0.547 0.453 0.000
E54 Ascorbic acid deficiency
0.547 0.453 0.000
E52 Niacin deficiency [pellagra]
0.547 0.453 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.546 0.454 0.000
C50.6 Axillary tail of breast
0.000 0.455 0.545
C76.1 Thorax
0.000 0.457 0.543
I22.9 Subsequent myocardial infarction of unspecified site
0.543 0.457 0.000
I30-I52 Other forms of heart disease
0.538 0.462 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.463 0.537
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.463 0.537
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.463 0.537
C84.3 Lymphoepithelioid lymphoma
0.000 0.463 0.537
C84.2 T-zone lymphoma
0.000 0.463 0.537
C84.1 Sezary's diease
0.000 0.463 0.537
C23 Malignant neoplasm of gallbladder
0.000 0.465 0.535
C82.2 Large cell, follicular
0.000 0.469 0.531
I74.8 Embolism and thrombosis of other arteries
0.530 0.470 0.000
C81.1 Nodular sclerosis
0.000 0.470 0.529
C90.3 Solitary plasmacytoma
0.000 0.471 0.529
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.528 0.472 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.528 0.472 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.526 0.474 0.000
I79.1 Aortitis in diseases classified elsewhere
0.525 0.475 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.525 0.475 0.000
C58 Malignant neoplasm of placenta
0.000 0.475 0.525
C52 Malignant neoplasm of vagina
0.000 0.481 0.519
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.518 0.482 0.000
E07.9 Disorder of thyroid, unspecified
0.518 0.482 0.000
C50.2 Upper-inner quadrant of breast
0.000 0.482 0.518
I05.1 Rheumatic mitral insufficiency
0.518 0.482 0.000
I05.8 Other mitral valve diseases
0.516 0.483 0.000
C18 Malignant neoplasm of colon
0.000 0.485 0.515
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.485 0.515
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.485 0.515
C92.3 Myeloid sarcoma
0.000 0.485 0.515
C92.2 Subacute myeloid leukaemia
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.513 0.487 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.513 0.487 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.513 0.487 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.513 0.487 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.513 0.487 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.513 0.487 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.513 0.487 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.513 0.487 0.000
E56 Other vitamin deficiencies
0.511 0.488 0.000
I35.0 Aortic (valve) stenosis
0.510 0.490 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.510 0.490 0.000
E12.9 Without complications
0.509 0.491 0.000
E12.8 With unspecified complications
0.509 0.491 0.000
E12.7 With multiple complications
0.509 0.491 0.000
E12.6 With other specified complications
0.509 0.491 0.000
E12.5 With peripheral circulatory complications
0.509 0.491 0.000
E12.4 With neurological complications
0.509 0.491 0.000
E12.3 With ophthalmic complications
0.509 0.491 0.000
E12.2 With renal complications
0.509 0.491 0.000
E12.1 With ketoacidosis
0.509 0.491 0.000
E12.0 With coma
0.509 0.491 0.000
C37 Malignant neoplasm of thymus
0.000 0.491 0.509
I36 Nonrheumatic tricuspid valve disorders
0.508 0.492 0.000
C92.1 Chronic myeloid leukaemia
0.000 0.492 0.508
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.492 0.508
E29 Testicular dysfunction
0.507 0.492 0.000
C45.2 Mesothelioma of pericardium
0.000 0.496 0.504
C45.1 Mesothelioma of peritoneum
0.000 0.496 0.504
I72 Other aneurysm
0.502 0.498 0.000
E31.0 Autoimmune polyglandular failure
0.501 0.499 0.000
C45.9 Mesothelioma, unspecified
0.000 0.499 0.501
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.500 0.500 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.000 0.500 0.500
I71.8 Aortic aneurysm of unspecified site, ruptured
0.500 0.500 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.500 0.500 0.000
C38.4 Pleura
0.000 0.500 0.500
C77.1 Intrathoracic lymph nodes
0.000 0.500 0.500
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.499 0.501 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.498 0.502 0.000
E34.9 Endocrine disorder, unspecified
0.497 0.503 0.000
M08 Juvenile arthritis
0.497 0.503 0.000
C49.0 Connective and soft tissue of head, face and neck
0.000 0.504 0.496
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.504 0.496
C21 Malignant neoplasm of anus and anal canal
0.000 0.505 0.495
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.506 0.494
C95.0 Acute leukaemia of unspecified cell type
0.000 0.507 0.493
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.493 0.507 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.493 0.507 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.509 0.491
C81.3 Lymphocytic depletion
0.000 0.509 0.491
M05.1 Rheumatoid lung disease
0.490 0.510 0.000
C91.4 Hairy-cell leukaemia
0.000 0.510 0.490
E34.0 Carcinoid syndrome
0.489 0.510 0.000
C51.8 Overlapping lesion of vulva
0.000 0.511 0.489
C51.2 Clitoris
0.000 0.511 0.489
C51.1 Labium minus
0.000 0.511 0.489
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.487 0.512 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.487 0.513 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.487 0.513 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.486 0.514 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.485 0.515 0.000
C18.2 Ascending colon
0.000 0.515 0.485
Z95.0 Presence of cardiac pacemaker
0.485 0.515 0.000
E53 Deficiency of other B group vitamins
0.485 0.515 0.000
M06.8 Other specified rheumatoid arthritis
0.484 0.516 0.000
C48.1 Specified parts of peritoneum
0.000 0.518 0.482
E28.9 Ovarian dysfunction, unspecified
0.481 0.519 0.000
E28.8 Other ovarian dysfunction
0.481 0.519 0.000
E28.1 Androgen excess
0.481 0.519 0.000
E28.0 Oestrogen excess
0.481 0.519 0.000
I78 Diseases of capillaries
0.480 0.520 0.000
I11 Hypertensive heart disease
0.479 0.521 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.521 0.478
M06.2 Rheumatoid bursitis
0.478 0.522 0.000
M06.1 Adult-onset Still's disease
0.478 0.522 0.000
E31.9 Polyglandular dysfunction, unspecified
0.477 0.522 0.000
E31.8 Other polyglandular dysfunction
0.477 0.522 0.000
E31.1 Polyglandular hyperfunction
0.477 0.522 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.524 0.476
C91.7 Other lymphoid leukaemia
0.000 0.524 0.476
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.524 0.476
C91.3 Prolymphocytic leukaemia
0.000 0.524 0.476
C91.2 Subacute lymphocytic leukaemia
0.000 0.524 0.476
C51.0 Labium majus
0.000 0.524 0.476
E61.9 Deficiency of nutrient element, unspecified
0.475 0.525 0.000
E61.8 Deficiency of other specified nutrient elements
0.475 0.525 0.000
E61.7 Deficiency of multiple nutrient elements
0.475 0.525 0.000
E61.6 Vanadium deficiency
0.475 0.525 0.000
E61.5 Molybdenum deficiency
0.475 0.525 0.000
E61.4 Chromium deficiency
0.475 0.525 0.000
E61.3 Manganese deficiency
0.475 0.525 0.000
E61.0 Copper deficiency
0.475 0.525 0.000
C79.2 Secondary malignant neoplasm of skin
0.000 0.525 0.474
I21.2 Acute transmural myocardial infarction of other sites
0.474 0.526 0.000
E25.9 Adrenogenital disorder, unspecified
0.474 0.526 0.000
E25.8 Other adrenogenital disorders
0.474 0.526 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.472 0.528 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.529 0.471
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.470 0.530 0.000
E24 Cushing's syndrome
0.468 0.531 0.000
E34.5 Androgen resistance syndrome
0.468 0.532 0.000
E34.4 Constitutional tall stature
0.468 0.532 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.468 0.532 0.000
E34.1 Other hypersecretion of intestinal hormones
0.468 0.532 0.000
C95.7 Other leukaemia of unspecified cell type
0.000 0.533 0.467
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.533 0.467
C93.1 Chronic monocytic leukaemia
0.000 0.534 0.466
E13.3 With ophthalmic complications
0.465 0.535 0.000
E07.1 Dyshormogenetic goitre
0.465 0.535 0.000
E07.0 Hypersecretion of calcitonin
0.465 0.535 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.464 0.536 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.464 0.536 0.000
E16.4 Abnormal secretion of gastrin
0.464 0.536 0.000
E16.3 Increased secretion of glucagon
0.464 0.536 0.000
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.537 0.463
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.462 0.538 0.000
C95.9 Leukaemia, unspecified
0.000 0.539 0.461
I07.1 Tricuspid insufficiency
0.461 0.539 0.000
E30.9 Disorder of puberty, unspecified
0.460 0.539 0.000
E30.8 Other disorders of puberty
0.460 0.539 0.000
E30.1 Precocious puberty
0.460 0.539 0.000
E30.0 Delayed puberty
0.460 0.539 0.000
E32.9 Disease of thymus, unspecified
0.460 0.539 0.000
E32.8 Other diseases of thymus
0.460 0.539 0.000
E32.1 Abscess of thymus
0.460 0.539 0.000
E32.0 Persistent hyperplasia of thymus
0.460 0.539 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.460 0.539 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.460 0.539 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.460 0.539 0.000
C93.9 Monocytic leukaemia, unspecified
0.000 0.541 0.459
C93.7 Other monocytic leukaemia
0.000 0.541 0.459
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.541 0.459
C93.2 Subacute monocytic leukaemia
0.000 0.541 0.459
C93.0 Acute monocytic leukaemia
0.000 0.541 0.459
E27.3 Drug-induced adrenocortical insufficiency
0.459 0.541 0.000
C81.7 Other Hodgkin's disease
0.000 0.541 0.459
M05.0 Felty's syndrome
0.458 0.542 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.543 0.457
E22.9 Hyperfunction of pituitary gland, unspecified
0.455 0.545 0.000
E22.8 Other hyperfunction of pituitary gland
0.455 0.545 0.000
C94.7 Other specified leukaemias
0.000 0.545 0.454
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.545 0.454
C94.5 Acute myelofibrosis
0.000 0.545 0.454
C94.4 Acute panmyelosis
0.000 0.545 0.454
C94.3 Mast cell leukaemia
0.000 0.545 0.454
C94.2 Acute megakaryoblastic leukaemia
0.000 0.545 0.454
C94.1 Chronic erythraemia
0.000 0.545 0.454
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.545 0.454
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.545 0.454
C96.8 Histiocytic sarcoma
0.000 0.545 0.454
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.545 0.454
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.545 0.454
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.545 0.454
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.545 0.454
C96.3 True histiocytic lymphoma
0.000 0.545 0.454
C96.2 Malignant mast cell tumour
0.000 0.545 0.454
C96.1 Malignant histiocytosis
0.000 0.545 0.454
C96.0 Letterer-Siwe disease
0.000 0.545 0.454
E61.2 Magnesium deficiency
0.454 0.546 0.000
E27.9 Disorder of adrenal gland, unspecified
0.454 0.546 0.000
M06.0 Seronegative rheumatoid arthritis
0.454 0.546 0.000
C92.5 Acute myelomonocytic leukaemia
0.000 0.546 0.454
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.547 0.453
C86.4 Blastic NK-cell lymphoma
0.000 0.547 0.453
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.547 0.453
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.547 0.453

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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