TreeWAS – Variant ID: rs6982502

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.998	0.002	0.000
E78.5 Hyperlipidaemia, unspecified	0.996	0.004	0.000
I25 Chronic ischaemic heart disease	0.969	0.031	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.891	0.109	0.000
I25.3 Aneurysm of heart	0.878	0.122	0.000
E78.4 Other hyperlipidaemia	0.860	0.140	0.000
I25.4 Coronary artery aneurysm	0.855	0.145	0.000
E78.2 Mixed hyperlipidaemia	0.841	0.159	0.000
E78.8 Other disorders of lipoprotein metabolism	0.799	0.201	0.000
E78.1 Pure hyperglyceridaemia	0.796	0.204	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.793	0.207	0.000
I25.2 Old myocardial infarction	0.783	0.217	0.000
E78.3 Hyperchylomicronaemia	0.716	0.284	0.000
E78.6 Lipoprotein deficiency	0.715	0.285	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.702	0.298	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.663	0.337	0.000
I25.6 Silent myocardial ischaemia	0.637	0.362	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.607	0.393	0.000
I25.5 Ischaemic cardiomyopathy	0.528	0.472	0.000
Z95.1 Presence of aortocoronary bypass graft	0.336	0.664	0.000
I20-I25 Ischaemic heart diseases	0.249	0.751	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.247	0.753	0.000
I21 Acute myocardial infarction	0.242	0.758	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.212	0.788	0.000
K76 Other diseases of liver	0.196	0.804	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.174	0.826	0.000
K76.6 Portal hypertension	0.167	0.833	0.000
I21.4 Acute subendocardial myocardial infarction	0.152	0.848	0.000
K76.7 Hepatorenal syndrome	0.151	0.849	0.000
I23 Certain current complications following acute myocardial infarction	0.148	0.851	0.000
K76.5 Hepatic veno-occlusive disease	0.140	0.859	0.000
K76.4 Peliosis hepatis	0.140	0.859	0.000
K76.3 Infarction of liver	0.140	0.859	0.000
K76.2 Central haemorrhagic necrosis of liver	0.140	0.859	0.000
K76.9 Liver disease, unspecified	0.139	0.861	0.000
I78.1 Naevus, nonneoplastic	0.137	0.863	0.000
I78 Diseases of capillaries	0.130	0.870	0.000
K76.1 Chronic passive congestion of liver	0.129	0.871	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.122	0.878	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.117	0.883	0.000
I21.9 Acute myocardial infarction, unspecified	0.112	0.888	0.000
I73.9 Peripheral vascular disease, unspecified	0.109	0.891	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.108	0.892	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.106	0.893	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.106	0.893	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.106	0.893	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.106	0.893	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.106	0.893	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.106	0.893	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.106	0.893	0.000
I73 Other peripheral vascular diseases	0.106	0.894	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.106	0.894	0.000
I71 Aortic aneurysm and dissection	0.102	0.898	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.100	0.900	0.000
I22 Subsequent myocardial infarction	0.100	0.900	0.000
I78.9 Disease of capillaries, unspecified	0.097	0.903	0.000
I73.8 Other specified peripheral vascular diseases	0.092	0.908	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.086	0.914	0.000
I78.8 Other diseases of capillaries	0.082	0.918	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.082	0.918	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.079	0.921	0.000
I71.0 Dissection of aorta [any part]	0.079	0.921	0.000
I23.8 Other current complications following acute myocardial infarction	0.076	0.924	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.076	0.924	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.073	0.927	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.073	0.927	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.070	0.930	0.000
I72 Other aneurysm	0.067	0.933	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.066	0.933	0.000
I20 Angina pectoris	0.066	0.934	0.000
Chapter IX Diseases of the circulatory system	0.065	0.935	0.000
I74 Arterial embolism and thrombosis	0.062	0.938	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.062	0.938	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.057	0.943	0.000
I72.2 Aneurysm of renal artery	0.055	0.945	0.000
I72.1 Aneurysm of artery of upper extremity	0.055	0.945	0.000
I72.3 Aneurysm of iliac artery	0.055	0.945	0.000
I74.5 Embolism and thrombosis of iliac artery	0.052	0.948	0.000
I00-I02 Acute rheumatic fever	0.051	0.949	0.000
I72.8 Aneurysm of other specified arteries	0.050	0.950	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.049	0.951	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.048	0.952	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.048	0.952	0.000
I24 Other acute ischaemic heart diseases	0.048	0.952	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.047	0.953	0.000
I20.8 Other forms of angina pectoris	0.046	0.954	0.000
I79.1 Aortitis in diseases classified elsewhere	0.045	0.955	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.045	0.955	0.000
I70 Atherosclerosis	0.044	0.956	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.043	0.957	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.043	0.957	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.041	0.958	0.000
I22.8 Subsequent myocardial infarction of other sites	0.041	0.959	0.000
I00 Rheumatic fever without mention of heart involvement	0.041	0.959	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.040	0.960	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.037	0.963	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.037	0.963	0.000
I02 Rheumatic chorea	0.036	0.963	0.000
I01 Rheumatic fever with heart involvement	0.036	0.963	0.000
I70.8 Atherosclerosis of other arteries	0.034	0.965	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.034	0.966	0.000
I10-I15 Hypertensive diseases	0.034	0.966	0.000
I20.0 Unstable angina	0.033	0.967	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.033	0.967	0.000
I50.1 Left ventricular failure	0.033	0.967	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.032	0.967	0.000
I72.4 Aneurysm of artery of lower extremity	0.032	0.967	0.000
I74.8 Embolism and thrombosis of other arteries	0.032	0.968	0.000
I72.9 Aneurysm of unspecified site	0.032	0.968	0.000
I20.1 Angina pectoris with documented spasm	0.032	0.968	0.000
I24.1 Dressler's syndrome	0.032	0.968	0.000
I70.1 Atherosclerosis of renal artery	0.030	0.970	0.000
K76.8 Other specified diseases of liver	0.030	0.970	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.030	0.970	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.029	0.971	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.029	0.971	0.000
I13 Hypertensive heart and renal disease	0.028	0.972	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.028	0.972	0.000
I70.9 Generalised and unspecified atherosclerosis	0.027	0.972	0.000
I72.0 Aneurysm of carotid artery	0.027	0.972	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.027	0.973	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.027	0.973	0.000
I98.0 Cardiovascular syphilis	0.027	0.973	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.027	0.973	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.026	0.973	0.000
I01.8 Other acute rheumatic heart disease	0.026	0.973	0.000
I01.2 Acute rheumatic myocarditis	0.026	0.973	0.000
I01.1 Acute rheumatic endocarditis	0.026	0.973	0.000
I01.0 Acute rheumatic pericarditis	0.026	0.973	0.000
I02.9 Rheumatic chorea without heart involvement	0.026	0.973	0.000
I02.0 Rheumatic chorea with heart involvement	0.026	0.973	0.000
I20.9 Angina pectoris, unspecified	0.026	0.974	0.000
I70.0 Atherosclerosis of aorta	0.025	0.975	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.025	0.975	0.000
I11 Hypertensive heart disease	0.025	0.975	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.024	0.976	0.000
I15 Secondary hypertension	0.023	0.977	0.000
I99 Other and unspecified disorders of circulatory system	0.023	0.977	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.022	0.978	0.000
I12 Hypertensive renal disease	0.022	0.978	0.000
I73.0 Raynaud's syndrome	0.022	0.978	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.020	0.980	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.020	0.980	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.020	0.980	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.020	0.980	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.020	0.980	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.020	0.980	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.020	0.980	0.000
I12.9 Hypertensive renal disease without renal failure	0.020	0.980	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.019	0.981	0.000
I97.0 Postcardiotomy syndrome	0.019	0.981	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.019	0.981	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.019	0.981	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.018	0.982	0.000
I97.1 Other functional disturbances following cardiac surgery	0.018	0.982	0.000
I15.1 Hypertension secondary to other renal disorders	0.017	0.983	0.000
I50 Heart failure	0.017	0.983	0.000
B34.9 Viral infection, unspecified	0.017	0.983	0.000
I77 Other disorders of arteries and arterioles	0.017	0.983	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.017	0.983	0.000
I15.8 Other secondary hypertension	0.017	0.983	0.000
I15.2 Hypertension secondary to endocrine disorders	0.017	0.983	0.000
I15.9 Seconday hypertension, unspecified	0.016	0.984	0.000
I50.0 Congestive heart failure	0.016	0.984	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.016	0.984	0.001
I15.0 Renovascular hypertension	0.015	0.984	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.015	0.984	0.000
E10.3 With ophthalmic complications	0.000	0.985	0.015
I11.9 Hypertensive heart disease without (congestive) heart failure	0.015	0.985	0.000
B34 Viral infection of unspecified site	0.015	0.985	0.000
I28 Other diseases of pulmonary vessels	0.014	0.986	0.000
B34.8 Other viral infections of unspecified site	0.013	0.987	0.000
B34.4 Papovirus infection, unspecified	0.013	0.987	0.000
I77.5 Necrosis of artery	0.012	0.987	0.000
I77.4 Coeliac artery compression syndrome	0.012	0.987	0.000
I77.3 Arterial fibromuscular dysplasia	0.012	0.987	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.988	0.012
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.012	0.988	0.000
I24.8 Other forms of acute ischaemic heart disease	0.012	0.988	0.000
I05-I09 Chronic rheumatic heart diseases	0.012	0.988	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.011	0.988	0.000
I77.8 Other specified disorders of arteries and arterioles	0.011	0.989	0.000
B34.3 Parvovirus infection, unspecified	0.011	0.989	0.000
B34.2 Coronavirus infection, unspecified	0.011	0.989	0.000
B34.1 Enterovirus infection, unspecified	0.011	0.989	0.000
B34.0 Adenovirus infection, unspecified	0.011	0.989	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.989	0.011
I77.0 Arteriovenous fistula, acquired	0.010	0.989	0.000
I77.2 Rupture of artery	0.010	0.989	0.000
E10.4 With neurological complications	0.000	0.990	0.010
I77.9 Disorder of arteries and arterioles, unspecified	0.010	0.990	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.010	0.990	0.000
I28.1 Aneurysm of pulmonary artery	0.010	0.990	0.000
I77.1 Stricture of artery	0.010	0.990	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.010	0.990	0.000
I95 Hypotension	0.010	0.990	0.000
I28.8 Other specified diseases of pulmonary vessels	0.010	0.990	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.010	0.990	0.000
E10.5 With peripheral circulatory complications	0.000	0.990	0.010
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.009	0.990	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.008	0.991	0.001
K81.9 Cholecystitis, unspecified	0.000	0.991	0.009
I95.0 Idiopathic hypotension	0.009	0.991	0.000
I10 Essential (primary) hypertension	0.009	0.991	0.000
B25-B34 Other viral diseases	0.009	0.991	0.000
B27 Infectious mononucleosis	0.009	0.991	0.000
B27.9 Infectious mononucleosis, unspecified	0.009	0.991	0.000
K70-K77 Diseases of liver	0.009	0.991	0.000
I06 Rheumatic aortic valve diseases	0.008	0.992	0.000
T39.0 Salicylates	0.000	0.992	0.008
E10.6 With other specified complications	0.000	0.992	0.008
U89.8 Agent resistant to other single specified antibiotic	0.008	0.992	0.000
E10.0 With coma	0.000	0.992	0.008
E10.1 With ketoacidosis	0.000	0.992	0.008
E10.2 With renal complications	0.000	0.992	0.008
E10.7 With multiple complications	0.000	0.992	0.008
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.992	0.008
I07 Rheumatic tricuspid valve diseases	0.008	0.992	0.000
E10.8 With unspecified complications	0.000	0.992	0.007
I09 Other rheumatic heart diseases	0.007	0.992	0.000
I95.8 Other hypotension	0.007	0.992	0.000
K71 Toxic liver disease	0.007	0.993	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.993	0.007
B27.0 Gammaherpesviral mononucleosis	0.007	0.993	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.993	0.007
I06.1 Rheumatic aortic insufficiency	0.007	0.993	0.000
B30 Viral conjunctivitis	0.007	0.993	0.000
B26 Mumps	0.006	0.993	0.000
B27.8 Other infectious mononucleosis	0.006	0.993	0.000
B27.1 Cytomegaloviral mononucleosis	0.006	0.993	0.000
I60-I69 Cerebrovascular diseases	0.007	0.993	0.000
K77 Liver disorders in diseases classified elsewhere	0.006	0.994	0.000
U89 Agent resistant to other and unspecified antibiotics	0.006	0.994	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.006	0.994	0.000
I06.8 Other rheumatic aortic valve diseases	0.006	0.994	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.006	0.994	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.006	0.994	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.006	0.994	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.006	0.994	0.000
B33 Other viral diseases, not elsewhere classified	0.006	0.994	0.000
R82.9 Other and unspecified abnormal finding in urine	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.994	0.006
T39.2 Pyrazolone derivatives	0.000	0.994	0.006
I07.9 Tricuspid valve disease, unspecified	0.006	0.994	0.000
I07.8 Other tricuspid valve diseases	0.006	0.994	0.000
I07.2 Tricuspid stenosis with insufficiency	0.006	0.994	0.000
I07.0 Tricuspid stenosis	0.006	0.994	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.994	0.006
K73 Chronic hepatitis, not elsewhere classified	0.006	0.994	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.006	0.994	0.000
I27 Other pulmonary heart diseases	0.006	0.994	0.000
I63 Cerebral infarction	0.006	0.994	0.000
I09.8 Other specified rheumatic heart diseases	0.005	0.994	0.000
I09.2 Chronic rheumatic pericarditis	0.005	0.994	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.005	0.994	0.000
I09.0 Rheumatic myocarditis	0.005	0.994	0.000
I06.0 Rheumatic aortic stenosis	0.005	0.994	0.000
I95.2 Hypotension due to drugs	0.006	0.994	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.005	0.994	0.000
I61 Intracerebral haemorrhage	0.006	0.994	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.994	0.005
I26 Pulmonary embolism	0.005	0.994	0.000
I35 Nonrheumatic aortic valve disorders	0.005	0.995	0.000
K71.9 Toxic liver disease, unspecified	0.005	0.995	0.000
K71.8 Toxic liver disease with other disorders of liver	0.005	0.995	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.005	0.995	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.005	0.995	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.005	0.995	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.005	0.995	0.000
K71.2 Toxic liver disease with acute hepatitis	0.005	0.995	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.005	0.995	0.000
B30.9 Viral conjunctivitis, unspecified	0.005	0.995	0.000
K71.0 Toxic liver disease with cholestasis	0.005	0.995	0.000
U89.9 Agent resistant to unspecified antibiotic	0.005	0.995	0.000
I07.1 Tricuspid insufficiency	0.005	0.995	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.005	0.995	0.000
I77.6 Arteritis, unspecified	0.005	0.995	0.000
B30.8 Other viral conjunctivitis	0.005	0.995	0.000
B30.3 Acute epidemic haemorrhagic conjunctivitis (enteroviral)	0.005	0.995	0.000
B30.2 Viral pharyngoconjunctivitis	0.005	0.995	0.000
B30.1 Conjunctivitis due to adenovirus	0.005	0.995	0.000
B30.0 Keratoconjunctivitis due to adenovirus	0.005	0.995	0.000
I50.9 Heart failure, unspecified	0.005	0.995	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.005	0.995	0.000
I63.8 Other cerebral infarction	0.005	0.995	0.000
B26.9 Mumps without complication	0.005	0.995	0.000
B26.8 Mumps with other complications	0.005	0.995	0.000
B26.3 Mumps pancreatitis	0.005	0.995	0.000
B26.2 Mumps encephalitis	0.005	0.995	0.000
B26.1 Mumps meningitis	0.005	0.995	0.000
B26.0 Mumps orchitis	0.005	0.995	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.995	0.005
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
B33.0 Epidemic myalgia	0.005	0.995	0.000
I35.0 Aortic (valve) stenosis	0.005	0.995	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.005	0.995	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.995	0.005
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.995	0.005
I60.8 Other subarachnoid haemorrhage	0.005	0.995	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.005	0.995	0.000
B25 Cytomegaloviral disease	0.005	0.995	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.995	0.005
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.005	0.995	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.005	0.995	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.005	0.995	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.005	0.995	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.005	0.995	0.000
I60 Subarachnoid haemorrhage	0.005	0.995	0.000
B33.4 Hantavirus (cardio-)pulmonary syndrome [HPS] [HCPS]	0.004	0.995	0.000
B33.3 Retrovirus infections, not elsewhere classified	0.004	0.995	0.000
B33.1 Ross River disease	0.004	0.995	0.000
I09.9 Rheumatic heart disease, unspecified	0.004	0.995	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.005	0.995	0.000
K73.9 Chronic hepatitis, unspecified	0.005	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.995	0.004
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.995	0.005
I35.9 Aortic valve disorder, unspecified	0.005	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.995	0.004
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.004
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.995	0.004
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.995	0.004
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.995	0.004
T44.0 Anticholinesterase agents	0.000	0.995	0.004
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.005	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.995	0.004
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.004	0.995	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.004	0.995	0.000
I27.1 Kyphoscoliotic heart disease	0.004	0.996	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.004	0.996	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.004	0.996	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.004	0.996	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.996	0.004
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.004	0.996	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.004	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.004
K72 Hepatic failure, not elsewhere classified	0.004	0.996	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.004	0.996	0.000
B33.8 Other specified viral diseases	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.004	0.996	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.004	0.996	0.000
I30-I52 Other forms of heart disease	0.004	0.996	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.004	0.996	0.000
B33.2 Viral carditis	0.004	0.996	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.004	0.996	0.000
T50.8 Diagnostic agents	0.000	0.996	0.004
S82.10 Fracture of upper end of tibia (closed)	0.000	0.996	0.004
T50.4 Drugs affecting uric acid metabolism	0.000	0.996	0.004
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.000	0.996	0.004
T50.5 Appetite depressants	0.000	0.996	0.004
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.996	0.004
T50.1 Loop [high-ceiling] diuretics	0.000	0.996	0.004
T50.0 Mineralocorticoids and their antagonists	0.000	0.996	0.004
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.996	0.004
I61.8 Other intracerebral haemorrhage	0.004	0.996	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.004	0.996	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.004	0.996	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.004	0.996	0.000
B25.2 Cytomegaloviral pancreatitis	0.003	0.996	0.000
B25.1 Cytomegaloviral hepatitis	0.003	0.996	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.996	0.004
I27.9 Pulmonary heart disease, unspecified	0.004	0.996	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.003	0.996	0.000
I37 Pulmonary valve disorders	0.004	0.996	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.004	0.996	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.996	0.004
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.996	0.003
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.996	0.003
U84 Resistance to other antimicrobial drugs	0.003	0.996	0.000
U83 Resistance to other antibiotics	0.003	0.996	0.000
U82 Resistance to betalactam antibiotics	0.003	0.996	0.000
U85 Resistance to antineoplastic drugs	0.003	0.996	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.003	0.997	0.000
U88 Agent resistant to multiple antibiotics	0.003	0.997	0.000
S82.70 Multiple fractures of lower leg (closed)	0.000	0.997	0.003
K74 Fibrosis and cirrhosis of liver	0.003	0.997	0.000
K81 Cholecystitis	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.003
T37.5 Antiviral drugs	0.000	0.997	0.003
T37.4 Anthelminthics	0.000	0.997	0.003
T37.3 Other antiprotozoal drugs	0.000	0.997	0.003
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.003
T37.1 Antimycobacterial drugs	0.000	0.997	0.003
T37.0 Sulphonamides	0.000	0.997	0.003
I05 Rheumatic mitral valve diseases	0.003	0.997	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.003	0.997	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.003	0.997	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I27.0 Primary pulmonary hypertension	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.003	0.997	0.000
K72.0 Acute and subacute hepatic failure	0.003	0.997	0.000
I52 Other heart disorders in diseases classified elsewhere	0.003	0.997	0.000
I48 Atrial fibrillation and flutter	0.003	0.997	0.000
I41 Myocarditis in diseases classified elsewhere	0.003	0.997	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.003	0.997	0.000
I32 Pericarditis in diseases classified elsewhere	0.003	0.997	0.000
B25.9 Cytomegaloviral disease, unspecified	0.003	0.997	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.000	0.997	0.003
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.003	0.997	0.000
B25.0 Cytomegaloviral pneumonitis	0.003	0.997	0.000
I37.1 Pulmonary valve insufficiency	0.003	0.997	0.000
I40 Acute myocarditis	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
Chapter XXII Codes for special purposes	0.003	0.997	0.000
K81.0 Acute cholecystitis	0.000	0.997	0.003
S82.1 Fracture of upper end of tibia	0.000	0.997	0.003
U80 Agent resistant to penicillin and related antibiotics	0.003	0.997	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.003	0.997	0.000
K75 Other inflammatory liver diseases	0.003	0.997	0.000
B25.8 Other cytomegaloviral diseases	0.003	0.997	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.997	0.003
K75.3 Granulomatous hepatitis, not elsewhere classified	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.997	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.003
T38.7 Androgens and anabolic congeners	0.000	0.997	0.003
T38.5 Other oestrogens and progestogens	0.000	0.997	0.003
T38.4 Oral contraceptives	0.000	0.997	0.003
T38.2 Antithyroid drugs	0.000	0.997	0.003
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.997	0.003
I62 Other nontraumatic intracranial haemorrhage	0.003	0.997	0.000
K72.1 Chronic hepatic failure	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.003
R82 Other abnormal findings in urine	0.003	0.997	0.000
I42.6 Alcoholic cardiomyopathy	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.000	0.997	0.003
U51.0 Not Previously admitted to a psyciatric hospital	0.003	0.997	0.000
H93.1 Tinnitus	0.003	0.997	0.000
K74.1 Hepatic sclerosis	0.003	0.997	0.000
I95.1 Orthostatic hypotension	0.003	0.997	0.000
U51 Admission status on psychiatric patients	0.003	0.997	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.003	0.997	0.000
Z89.9 Acquired absence of limb, unspecified	0.000	0.997	0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.997	0.003
S82.11 Fracture of upper end of tibia (open)	0.000	0.997	0.003
L43.9 Lichen planus, unspecified	0.000	0.997	0.003
U81 Agent resistant to vancomycin and related antibiotics	0.003	0.997	0.000
I37.9 Pulmonary valve disorder, unspecified	0.003	0.997	0.000
I37.8 Other pulmonary valve disorders	0.003	0.997	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.003	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
I68.0 Cerebral amyloid angiopathy	0.002	0.997	0.000
T41.5 Therapeutic gases	0.000	0.997	0.003
T41.4 Anaesthetic, unspecified	0.000	0.997	0.003
T41.3 Local anaesthetics	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
T41.1 Intravenous anaesthetics	0.000	0.997	0.003
T41.0 Inhaled anaesthetics	0.000	0.997	0.003
T49.9 Topical agent, unspecified	0.000	0.997	0.003
T49.8 Other topical agents	0.000	0.997	0.003
T49.7 Dental drugs, topically applied	0.000	0.997	0.003
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.003
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.003
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.003
T49.2 Local astringents and local detergents	0.000	0.997	0.003
T49.1 Antipruritics	0.000	0.997	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.003
I36 Nonrheumatic tricuspid valve disorders	0.003	0.997	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.003	0.997	0.000
U82.8 Resistance to other betalactam antibiotics	0.003	0.997	0.000
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.003	0.997	0.000
U82.1 Resistance to methicillin	0.003	0.997	0.000
U82.0 Resistance to penicillin	0.003	0.997	0.000
U83.9 Resistance to unspecified antibiotic	0.003	0.997	0.000
U83.8 Resistance to other single specified antibiotic	0.003	0.997	0.000
U83.7 Resistance to multiple antibiotics	0.003	0.997	0.000
U83.2 Resistance to quinolones	0.003	0.997	0.000
U83.1 Resistance to other vancomycin related antibiotics	0.003	0.997	0.000
U83.0 Resistance to vancomycin	0.003	0.997	0.000
U84.9 Resistance to unspecified antimicrobial drugs	0.003	0.997	0.000
U84.8 Resistance to other specified antimicrobial drug	0.003	0.997	0.000
U84.7 Resistance to multiple antimicrobial drugs	0.003	0.997	0.000
U84.3 Resistance to tuberculostatic drug(s)	0.003	0.997	0.000
U84.2 Resistance to antiviral drug(s)	0.003	0.997	0.000
U84.1 Resistance to antifungal drug(s)	0.003	0.997	0.000
U84.0 Resistance to antiparasitic drug(s)	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.003
K70.2 Alcoholic fibrosis and sclerosis of liver	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.000	0.997	0.003
K74.4 Secondary biliary cirrhosis	0.003	0.997	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.003	0.997	0.000
I37.0 Pulmonary valve stenosis	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.003	0.997	0.000
O72.0 Third-stage haemorrhage	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
K74.5 Biliary cirrhosis, unspecified	0.003	0.997	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations