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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17321515
log Bayes Factor = 32.222
Chromosome 8   position 126,486,409  (GRCh37) Explore rs17321515 on Ensembl!
Variant rs17321515 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.001 0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.003 0.997
E78.5 Hyperlipidaemia, unspecified
0.000 0.010 0.990
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.026 0.974
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.035 0.965
I25.3 Aneurysm of heart
0.000 0.061 0.939
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.069 0.931
E78.2 Mixed hyperlipidaemia
0.000 0.070 0.930
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.131 0.869
E78.4 Other hyperlipidaemia
0.000 0.138 0.862
E78.1 Pure hyperglyceridaemia
0.000 0.165 0.835
I25.4 Coronary artery aneurysm
0.000 0.176 0.824
E78.8 Other disorders of lipoprotein metabolism
0.000 0.251 0.749
E78.6 Lipoprotein deficiency
0.000 0.261 0.739
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.274 0.726
I25.2 Old myocardial infarction
0.000 0.322 0.678
I25.5 Ischaemic cardiomyopathy
0.000 0.328 0.671
I25.6 Silent myocardial ischaemia
0.000 0.340 0.659
E78.3 Hyperchylomicronaemia
0.000 0.400 0.600
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.460 0.540
I20-I25 Ischaemic heart diseases
0.000 0.482 0.518
I21 Acute myocardial infarction
0.000 0.484 0.516
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.580 0.420
I21.4 Acute subendocardial myocardial infarction
0.000 0.606 0.394
K76 Other diseases of liver
0.000 0.612 0.388
I50.1 Left ventricular failure
0.000 0.626 0.374
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.630 0.370
I23 Certain current complications following acute myocardial infarction
0.000 0.642 0.358
K76.7 Hepatorenal syndrome
0.000 0.659 0.341
K76.6 Portal hypertension
0.000 0.666 0.334
I50 Heart failure
0.000 0.701 0.299
I50.0 Congestive heart failure
0.000 0.708 0.292
K76.5 Hepatic veno-occlusive disease
0.000 0.722 0.278
K76.4 Peliosis hepatis
0.000 0.722 0.278
K76.3 Infarction of liver
0.000 0.722 0.278
K76.2 Central haemorrhagic necrosis of liver
0.000 0.722 0.278
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.743 0.256
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.743 0.256
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.743 0.256
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.743 0.256
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.743 0.256
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.743 0.256
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.743 0.256
K76.1 Chronic passive congestion of liver
0.000 0.750 0.249
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.754 0.245
I23.8 Other current complications following acute myocardial infarction
0.000 0.757 0.243
K76.9 Liver disease, unspecified
0.000 0.786 0.214
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.806 0.194
I22 Subsequent myocardial infarction
0.000 0.860 0.140
I24 Other acute ischaemic heart diseases
0.000 0.877 0.123
I21.9 Acute myocardial infarction, unspecified
0.000 0.890 0.110
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.909 0.091
I24.1 Dressler's syndrome
0.000 0.913 0.087
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.914 0.086
I35 Nonrheumatic aortic valve disorders
0.000 0.915 0.085
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.918 0.082
I50.9 Heart failure, unspecified
0.000 0.918 0.082
I35.0 Aortic (valve) stenosis
0.000 0.920 0.080
I30-I52 Other forms of heart disease
0.000 0.922 0.078
I35.9 Aortic valve disorder, unspecified
0.000 0.924 0.076
I20 Angina pectoris
0.000 0.924 0.076
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.926 0.074
K76.8 Other specified diseases of liver
0.000 0.927 0.073
Chapter IX Diseases of the circulatory system
0.000 0.929 0.071
I31 Other diseases of pericardium
0.000 0.932 0.068
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.934 0.066
I31.9 Disease of pericardium, unspecified
0.000 0.935 0.065
I47 Paroxysmal tachycardia
0.000 0.936 0.064
I37 Pulmonary valve disorders
0.000 0.938 0.062
I42 Cardiomyopathy
0.000 0.942 0.058
I47.1 Supraventricular tachycardia
0.000 0.943 0.057
I42.6 Alcoholic cardiomyopathy
0.000 0.944 0.056
I52 Other heart disorders in diseases classified elsewhere
0.000 0.944 0.056
I48 Atrial fibrillation and flutter
0.000 0.944 0.056
I41 Myocarditis in diseases classified elsewhere
0.000 0.944 0.056
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.944 0.056
I32 Pericarditis in diseases classified elsewhere
0.000 0.944 0.056
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.945 0.055
I40 Acute myocarditis
0.000 0.945 0.055
I00-I02 Acute rheumatic fever
0.000 0.945 0.055
I37.1 Pulmonary valve insufficiency
0.000 0.948 0.052
I33 Acute and subacute endocarditis
0.000 0.948 0.052
I47.2 Ventricular tachycardia
0.000 0.949 0.051
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.949 0.051
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.949 0.051
I35.1 Aortic (valve) insufficiency
0.000 0.949 0.051
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.949 0.051
I22.8 Subsequent myocardial infarction of other sites
0.001 0.950 0.050
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.950 0.049
I31.0 Chronic adhesive pericarditis
0.000 0.950 0.049
I31.8 Other specified diseases of pericardium
0.000 0.951 0.049
I31.2 Haemopericardium, not elsewhere classified
0.000 0.951 0.049
I78.1 Naevus, nonneoplastic
0.000 0.951 0.049
I20.8 Other forms of angina pectoris
0.000 0.953 0.047
I31.1 Chronic constrictive pericarditis
0.000 0.953 0.047
I78 Diseases of capillaries
0.000 0.953 0.047
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.955 0.045
I37.9 Pulmonary valve disorder, unspecified
0.000 0.955 0.045
I37.8 Other pulmonary valve disorders
0.000 0.955 0.045
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.955 0.045
I42.0 Dilated cardiomyopathy
0.000 0.955 0.045
I36 Nonrheumatic tricuspid valve disorders
0.000 0.955 0.044
I42.9 Cardiomyopathy, unspecified
0.000 0.956 0.044
K70-K77 Diseases of liver
0.000 0.956 0.044
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.956 0.044
I00 Rheumatic fever without mention of heart involvement
0.000 0.957 0.043
I37.0 Pulmonary valve stenosis
0.000 0.957 0.043
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.958 0.042
I42.5 Other restrictive cardiomyopathy
0.000 0.958 0.042
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.958 0.042
I40.9 Acute myocarditis, unspecified
0.000 0.959 0.041
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.959 0.041
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.959 0.040
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.959 0.040
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.959 0.040
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.959 0.040
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.959 0.040
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.959 0.040
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.959 0.040
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.959 0.040
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.959 0.040
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.959 0.040
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.959 0.040
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.959 0.040
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.959 0.040
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.959 0.040
I48.4 Atypical atrial flutter
0.000 0.959 0.040
I48.3 Typical atrial flutter
0.000 0.959 0.040
I48.2 Chronic atrial fibrillation
0.000 0.959 0.040
I48.1 Persistent atrial fibrillation
0.000 0.959 0.040
I48.0 Paroxysmal atrial fibrillation
0.000 0.959 0.040
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.959 0.040
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.959 0.040
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.959 0.040
I42.4 Endocardial fibroelastosis
0.000 0.960 0.040
I40.8 Other acute myocarditis
0.000 0.960 0.040
I40.1 Isolated myocarditis
0.000 0.960 0.040
I02 Rheumatic chorea
0.000 0.960 0.039
I01 Rheumatic fever with heart involvement
0.000 0.960 0.039
I30 Acute pericarditis
0.000 0.961 0.038
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.962 0.038
I35.8 Other aortic valve disorders
0.000 0.962 0.038
I40.0 Infective myocarditis
0.000 0.963 0.037
I34 Nonrheumatic mitral valve disorders
0.000 0.963 0.037
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.963 0.036
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.963 0.036
I98.0 Cardiovascular syphilis
0.000 0.963 0.036
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.964 0.036
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.964 0.036
I42.8 Other cardiomyopathies
0.000 0.964 0.036
I24.8 Other forms of acute ischaemic heart disease
0.000 0.964 0.035
I33.0 Acute and subacute infective endocarditis
0.000 0.965 0.035
I33.9 Acute endocarditis, unspecified
0.000 0.965 0.035
I38 Endocarditis, valve unspecified
0.000 0.965 0.035
I78.9 Disease of capillaries, unspecified
0.000 0.966 0.034
I31.3 Pericardial effusion (noninflammatory)
0.000 0.966 0.034
K73 Chronic hepatitis, not elsewhere classified
0.000 0.966 0.033
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.967 0.033
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.968 0.032
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.968 0.032
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.968 0.032
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.968 0.032
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.968 0.032
K71 Toxic liver disease
0.000 0.968 0.032
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.968 0.032
K77 Liver disorders in diseases classified elsewhere
0.000 0.968 0.032
K70 Alcoholic liver disease
0.000 0.968 0.032
I20.1 Angina pectoris with documented spasm
0.000 0.969 0.031
I99 Other and unspecified disorders of circulatory system
0.000 0.970 0.030
I71 Aortic aneurysm and dissection
0.000 0.970 0.030
I73 Other peripheral vascular diseases
0.000 0.971 0.029
I10-I15 Hypertensive diseases
0.000 0.971 0.029
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.971 0.028
I01.8 Other acute rheumatic heart disease
0.000 0.971 0.028
I01.2 Acute rheumatic myocarditis
0.000 0.971 0.028
I01.1 Acute rheumatic endocarditis
0.000 0.971 0.028
I01.0 Acute rheumatic pericarditis
0.000 0.971 0.028
I02.9 Rheumatic chorea without heart involvement
0.000 0.971 0.028
I02.0 Rheumatic chorea with heart involvement
0.000 0.971 0.028
I72 Other aneurysm
0.000 0.972 0.028
I30.8 Other forms of acute pericarditis
0.000 0.972 0.028
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.972 0.028
I78.8 Other diseases of capillaries
0.000 0.972 0.027
I20.9 Angina pectoris, unspecified
0.000 0.973 0.027
I47.0 Reentry ventricular arrhythmia
0.000 0.973 0.027
K73.9 Chronic hepatitis, unspecified
0.000 0.973 0.027
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.973 0.027
K70.3 Alcoholic cirrhosis of liver
0.000 0.973 0.027
I46 Cardiac arrest
0.000 0.974 0.026
I72.3 Aneurysm of iliac artery
0.000 0.974 0.026
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.974 0.026
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.974 0.026
I73.9 Peripheral vascular disease, unspecified
0.000 0.974 0.026
I20.0 Unstable angina
0.000 0.975 0.025
I34.0 Mitral (valve) insufficiency
0.000 0.975 0.025
K75 Other inflammatory liver diseases
0.000 0.975 0.025
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.975 0.025
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.976 0.024
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.976 0.024
K71.0 Toxic liver disease with cholestasis
0.000 0.976 0.024
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.976 0.024
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.976 0.024
I73.8 Other specified peripheral vascular diseases
0.000 0.976 0.024
I71.0 Dissection of aorta [any part]
0.000 0.976 0.024
I72.1 Aneurysm of artery of upper extremity
0.000 0.977 0.023
K71.8 Toxic liver disease with other disorders of liver
0.000 0.977 0.023
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.977 0.023
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.977 0.023
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.977 0.023
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.977 0.023
K71.2 Toxic liver disease with acute hepatitis
0.000 0.977 0.023
K70.9 Alcoholic liver disease, unspecified
0.000 0.977 0.023
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.977 0.023
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.977 0.023
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.977 0.023
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.977 0.023
I72.2 Aneurysm of renal artery
0.000 0.977 0.022
I11 Hypertensive heart disease
0.000 0.978 0.022
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.978 0.022
I30.1 Infective pericarditis
0.000 0.978 0.021
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.978 0.021
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.978 0.021
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.978 0.021
I12 Hypertensive renal disease
0.000 0.979 0.021
K70.4 Alcoholic hepatic failure
0.000 0.979 0.021
I72.8 Aneurysm of other specified arteries
0.000 0.979 0.021
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.979 0.021
I42.2 Other hypertrophic cardiomyopathy
0.000 0.979 0.021
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.979 0.021
I13 Hypertensive heart and renal disease
0.000 0.979 0.021
K70.0 Alcoholic fatty liver
0.000 0.979 0.021
I30.9 Acute pericarditis, unspecified
0.000 0.979 0.021
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.979 0.020
I74 Arterial embolism and thrombosis
0.000 0.979 0.021
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.979 0.020
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.979 0.020
I12.9 Hypertensive renal disease without renal failure
0.000 0.979 0.021
K72 Hepatic failure, not elsewhere classified
0.000 0.980 0.020
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.980 0.020
K70.1 Alcoholic hepatitis
0.000 0.980 0.020
K71.9 Toxic liver disease, unspecified
0.000 0.980 0.020
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.980 0.019
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.980 0.020
K75.0 Abscess of liver
0.000 0.981 0.019
I46.1 Sudden cardiac death, so described
0.000 0.981 0.019
Z95.1 Presence of aortocoronary bypass graft
0.000 0.981 0.019
I70 Atherosclerosis
0.000 0.982 0.018
K75.2 Nonspecific reactive hepatitis
0.000 0.982 0.018
K75.1 Phlebitis of portal vein
0.000 0.982 0.018
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.982 0.018
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.982 0.018
I95 Hypotension
0.000 0.982 0.018
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.982 0.017
K75.8 Other specified inflammatory liver diseases
0.000 0.983 0.017
I05-I09 Chronic rheumatic heart diseases
0.000 0.984 0.016
I74.5 Embolism and thrombosis of iliac artery
0.000 0.984 0.016
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.984 0.016
I28 Other diseases of pulmonary vessels
0.000 0.984 0.016
I79.1 Aortitis in diseases classified elsewhere
0.000 0.984 0.016
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.984 0.016
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.984 0.016
K74 Fibrosis and cirrhosis of liver
0.000 0.984 0.016
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.985 0.015
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.985 0.015
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.985 0.015
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.985 0.015
I95.0 Idiopathic hypotension
0.000 0.985 0.015
K72.0 Acute and subacute hepatic failure
0.000 0.985 0.015
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.985 0.014
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.986 0.014
I70.8 Atherosclerosis of other arteries
0.000 0.986 0.014
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.986 0.014
I51 Complications and ill-defined descriptions of heart disease
0.000 0.986 0.014
I15 Secondary hypertension
0.000 0.986 0.013
I72.4 Aneurysm of artery of lower extremity
0.000 0.987 0.013
I51.8 Other ill-defined heart diseases
0.000 0.987 0.013
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.987 0.013
K72.1 Chronic hepatic failure
0.000 0.987 0.013
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.987 0.013
K75.9 Inflammatory liver disease, unspecified
0.000 0.987 0.013
I70.1 Atherosclerosis of renal artery
0.000 0.987 0.012
E10.3 With ophthalmic complications
0.013 0.987 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.987 0.012
I72.9 Aneurysm of unspecified site
0.001 0.987 0.012
I28.8 Other specified diseases of pulmonary vessels
0.000 0.987 0.012
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.012 0.988 0.000
K75.4 Autoimmune hepatitis
0.000 0.988 0.012
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.988 0.012
K74.5 Biliary cirrhosis, unspecified
0.000 0.988 0.012
I74.8 Embolism and thrombosis of other arteries
0.000 0.988 0.012
I28.1 Aneurysm of pulmonary artery
0.000 0.988 0.012
I70.9 Generalised and unspecified atherosclerosis
0.000 0.988 0.011
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.988 0.012
K74.4 Secondary biliary cirrhosis
0.000 0.988 0.011
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.988 0.011
K74.1 Hepatic sclerosis
0.000 0.988 0.011
I46.9 Cardiac arrest, unspecified
0.000 0.988 0.012
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.989 0.011
I07 Rheumatic tricuspid valve diseases
0.000 0.989 0.011
I95.8 Other hypotension
0.000 0.989 0.011
I95.2 Hypotension due to drugs
0.000 0.989 0.011
I95.1 Orthostatic hypotension
0.000 0.989 0.011
I09 Other rheumatic heart diseases
0.000 0.989 0.011
I06 Rheumatic aortic valve diseases
0.000 0.989 0.011
I97.0 Postcardiotomy syndrome
0.000 0.989 0.011
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.989 0.011
I70.0 Atherosclerosis of aorta
0.000 0.989 0.011
K74.0 Hepatic fibrosis
0.000 0.989 0.011
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.989 0.010
I97.1 Other functional disturbances following cardiac surgery
0.000 0.990 0.010
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.990 0.010
I72.0 Aneurysm of carotid artery
0.001 0.990 0.010
B34.9 Viral infection, unspecified
0.000 0.990 0.010
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.990 0.010
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.990 0.010
I51.5 Myocardial degeneration
0.000 0.990 0.010
I97.9 Postprocedural disorder of circulatory system, unspecified
0.001 0.990 0.010
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.990 0.010
I34.1 Mitral (valve) prolapse
0.000 0.990 0.010
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.990 0.009
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.991 0.009
I15.8 Other secondary hypertension
0.000 0.991 0.009
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.991 0.009
I15.9 Seconday hypertension, unspecified
0.000 0.991 0.009
I15.1 Hypertension secondary to other renal disorders
0.000 0.991 0.009
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.001 0.991 0.009
I15.0 Renovascular hypertension
0.000 0.991 0.009
K74.6 Other and unspecified cirrhosis of liver
0.000 0.991 0.009
B34 Viral infection of unspecified site
0.000 0.991 0.009
I06.1 Rheumatic aortic insufficiency
0.000 0.991 0.009
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.009 0.991 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.991 0.008
I51.4 Myocarditis, unspecified
0.000 0.991 0.009
T39.0 Salicylates
0.009 0.991 0.000
I15.2 Hypertension secondary to endocrine disorders
0.000 0.991 0.008
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.991 0.008
I07.9 Tricuspid valve disease, unspecified
0.000 0.992 0.008
I07.8 Other tricuspid valve diseases
0.000 0.992 0.008
I07.2 Tricuspid stenosis with insufficiency
0.000 0.992 0.008
I07.0 Tricuspid stenosis
0.000 0.992 0.008
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.992 0.008
B34.4 Papovirus infection, unspecified
0.000 0.992 0.008
K72.9 Hepatic failure, unspecified
0.000 0.992 0.008
I06.8 Other rheumatic aortic valve diseases
0.000 0.992 0.008
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.992 0.008
I09.8 Other specified rheumatic heart diseases
0.000 0.992 0.008
I09.2 Chronic rheumatic pericarditis
0.000 0.992 0.008
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.992 0.008
I09.0 Rheumatic myocarditis
0.000 0.992 0.008
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.992 0.008
H26.4 After-cataract
0.000 0.992 0.008
I51.0 Cardiac septal defect, acquired
0.000 0.992 0.008
I07.1 Tricuspid insufficiency
0.000 0.992 0.008
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.008 0.992 0.000
B34.8 Other viral infections of unspecified site
0.000 0.992 0.008
I51.6 Cardiovascular disease, unspecified
0.000 0.992 0.008
I77 Other disorders of arteries and arterioles
0.000 0.992 0.008
I46.0 Cardiac arrest with successful resuscitation
0.000 0.992 0.008
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.992 0.007
I10 Essential (primary) hypertension
0.000 0.992 0.008
E10 Insulin-dependent diabetes mellitus
0.007 0.993 0.000
H26.2 Complicated cataract
0.000 0.993 0.007
I09.9 Rheumatic heart disease, unspecified
0.000 0.993 0.007
E10.4 With neurological complications
0.007 0.993 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.001 0.993 0.006
I06.0 Rheumatic aortic stenosis
0.000 0.993 0.007
I05 Rheumatic mitral valve diseases
0.000 0.993 0.007
E10.5 With peripheral circulatory complications
0.007 0.993 0.000
U89.8 Agent resistant to other single specified antibiotic
0.000 0.993 0.007
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.007 0.993 0.000
B34.3 Parvovirus infection, unspecified
0.000 0.993 0.006
B34.2 Coronavirus infection, unspecified
0.000 0.993 0.006
B34.0 Adenovirus infection, unspecified
0.000 0.993 0.006
T39.4 Antirheumatics, not elsewhere classified
0.006 0.993 0.000
T39.2 Pyrazolone derivatives
0.006 0.993 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.006 0.994 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.994 0.006
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.006 0.994 0.000
E10.2 With renal complications
0.006 0.994 0.000
J15.2 Pneumonia due to staphylococcus
0.000 0.994 0.006
B34.1 Enterovirus infection, unspecified
0.000 0.994 0.006
T50.9 Other and unspecified drugs, medicaments and biological substances
0.006 0.994 0.000
I26 Pulmonary embolism
0.000 0.994 0.006
T36-T50 Poisoning by drugs, medicaments and biological substances
0.006 0.994 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.006 0.994 0.000
I77.5 Necrosis of artery
0.000 0.994 0.006
I77.4 Coeliac artery compression syndrome
0.000 0.994 0.006
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.006 0.994 0.000
I77.8 Other specified disorders of arteries and arterioles
0.000 0.994 0.006
E10.8 With unspecified complications
0.006 0.994 0.000
E10.0 With coma
0.006 0.994 0.000
K29.6 Other gastritis
0.000 0.994 0.006
H26 Other cataract
0.000 0.994 0.006
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.995 0.005
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.005 0.995 0.000
T50.8 Diagnostic agents
0.005 0.995 0.000
E10.7 With multiple complications
0.005 0.995 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.995 0.005
T37.8 Other specified systemic anti-infectives and antiparasitics
0.005 0.995 0.000
J15.9 Bacterial pneumonia, unspecified
0.000 0.995 0.005
E10.6 With other specified complications
0.005 0.995 0.000
I77.3 Arterial fibromuscular dysplasia
0.000 0.995 0.005
I05.8 Other mitral valve diseases
0.000 0.995 0.005
T50.1 Loop [high-ceiling] diuretics
0.005 0.995 0.000
I27 Other pulmonary heart diseases
0.000 0.995 0.005
I77.2 Rupture of artery
0.000 0.995 0.005
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.995 0.005
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.005 0.995 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.005 0.995 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.005 0.995 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.005 0.995 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.005 0.995 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.005 0.995 0.000
T44.0 Anticholinesterase agents
0.005 0.995 0.000
I08 Multiple valve diseases
0.000 0.995 0.005
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.005 0.995 0.000
H26.1 Traumatic cataract
0.000 0.995 0.005
I05.9 Mitral valve disease, unspecified
0.000 0.995 0.005
T50.4 Drugs affecting uric acid metabolism
0.005 0.995 0.000
T50.7 Analeptics and opioid receptor antagonists
0.005 0.995 0.000
T50.5 Appetite depressants
0.005 0.995 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.005 0.995 0.000
T50.0 Mineralocorticoids and their antagonists
0.005 0.995 0.000
H26.0 Infantile, juvenile and presenile cataract
0.000 0.995 0.005
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.005 0.995 0.000
J15.8 Other bacterial pneumonia
0.000 0.995 0.005
U89 Agent resistant to other and unspecified antibiotics
0.000 0.995 0.005
T50.6 Antidotes and chelating agents, not elsewhere classified
0.005 0.995 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.004 0.995 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.005 0.995 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.001 0.995 0.004
I05.1 Rheumatic mitral insufficiency
0.000 0.995 0.004
B27.9 Infectious mononucleosis, unspecified
0.000 0.996 0.004
T41 Poisoning by anaesthetics and therapeutic gases
0.004 0.996 0.000
J15.5 Pneumonia due to Escherichia coli
0.000 0.996 0.004
I77.6 Arteritis, unspecified
0.000 0.996 0.004
D25.9 Leiomyoma of uterus, unspecified
0.000 0.996 0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.004 0.996 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.996 0.004
I77.0 Arteriovenous fistula, acquired
0.000 0.996 0.004
H26.3 Drug-induced cataract
0.000 0.996 0.004
I05.2 Mitral stenosis with insufficiency
0.000 0.996 0.004
B27 Infectious mononucleosis
0.000 0.996 0.004
E10.1 With ketoacidosis
0.004 0.996 0.000
I77.1 Stricture of artery
0.000 0.996 0.004
J15.3 Pneumonia due to streptococcus, group B
0.000 0.996 0.004
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.004 0.996 0.000
T37.5 Antiviral drugs
0.004 0.996 0.000
T37.4 Anthelminthics
0.004 0.996 0.000
T37.3 Other antiprotozoal drugs
0.004 0.996 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.004 0.996 0.000
T37.1 Antimycobacterial drugs
0.004 0.996 0.000
T37.0 Sulphonamides
0.004 0.996 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.996 0.004
T43.3 Phenothiazine antipsychotics and neuroleptics
0.004 0.996 0.000
B25-B34 Other viral diseases
0.000 0.996 0.004
T43.0 Tricyclic and tetracyclic antidepressants
0.004 0.996 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.004 0.996 0.000
J15.1 Pneumonia due to Pseudomonas
0.000 0.996 0.004
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.996 0.004
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.996 0.004
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.996 0.004
K74.3 Primary biliary cirrhosis
0.000 0.996 0.004
U89.9 Agent resistant to unspecified antibiotic
0.000 0.996 0.004
I27.1 Kyphoscoliotic heart disease
0.000 0.996 0.004
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.996 0.004
I08.0 Disorders of both mitral and aortic valves
0.000 0.996 0.004
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.004 0.996 0.000
T36 Poisoning by systemic antibiotics
0.004 0.996 0.000
I08.9 Multiple valve disease, unspecified
0.000 0.996 0.004
J15.4 Pneumonia due to other streptococci
0.000 0.996 0.004
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.004 0.996 0.000
I27.9 Pulmonary heart disease, unspecified
0.000 0.996 0.004
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.004 0.996 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.004 0.996 0.000
T43.6 Psychostimulants with abuse potential
0.003 0.996 0.000
T49.9 Topical agent, unspecified
0.003 0.996 0.000
T49.8 Other topical agents
0.003 0.996 0.000
T49.7 Dental drugs, topically applied
0.003 0.996 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.003 0.996 0.000
T49.5 Ophthalmological drugs and preparations
0.003 0.996 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.003 0.996 0.000
T49.3 Emollients, demulcents and protectants
0.003 0.996 0.000
T49.2 Local astringents and local detergents
0.003 0.996 0.000
T49.1 Antipruritics
0.003 0.996 0.000
T38.9 Other and unspecified hormone antagonists
0.003 0.996 0.000
T38.7 Androgens and anabolic congeners
0.003 0.996 0.000
T38.5 Other oestrogens and progestogens
0.003 0.996 0.000
T38.4 Oral contraceptives
0.003 0.996 0.000
T38.2 Antithyroid drugs
0.003 0.996 0.000
T38.0 Glucocorticoids and synthetic analogues
0.003 0.996 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.003 0.996 0.000
T38.1 Thyroid hormones and substitutes
0.003 0.996 0.000
T41.5 Therapeutic gases
0.003 0.996 0.000
T41.4 Anaesthetic, unspecified
0.003 0.996 0.000
T41.3 Local anaesthetics
0.003 0.996 0.000
T41.2 Other and unspecified general anaesthetics
0.003 0.996 0.000
T41.1 Intravenous anaesthetics
0.003 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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