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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2083637
log Bayes Factor = 18.8278
Chromosome 8   position 19,865,175  (GRCh37) Explore rs2083637 on Ensembl!
Variant rs2083637 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.001 0.999
I25.2 Old myocardial infarction
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.002 0.998
I22 Subsequent myocardial infarction
0.000 0.005 0.995
I20.0 Unstable angina
0.000 0.006 0.994
E78.5 Hyperlipidaemia, unspecified
0.000 0.014 0.986
E78.2 Mixed hyperlipidaemia
0.000 0.015 0.985
I21.9 Acute myocardial infarction, unspecified
0.000 0.020 0.980
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.021 0.979
I20.9 Angina pectoris, unspecified
0.000 0.023 0.977
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.024 0.976
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.027 0.973
I24 Other acute ischaemic heart diseases
0.000 0.035 0.965
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.050 0.950
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.074 0.926
I77 Other disorders of arteries and arterioles
0.000 0.081 0.919
I73 Other peripheral vascular diseases
0.000 0.087 0.913
I77.1 Stricture of artery
0.000 0.089 0.911
I71 Aortic aneurysm and dissection
0.000 0.089 0.911
I73.9 Peripheral vascular disease, unspecified
0.000 0.094 0.906
E78.1 Pure hyperglyceridaemia
0.000 0.100 0.900
I21.4 Acute subendocardial myocardial infarction
0.000 0.101 0.899
E78.4 Other hyperlipidaemia
0.000 0.101 0.899
I25.4 Coronary artery aneurysm
0.000 0.107 0.893
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.116 0.884
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.143 0.857
I70 Atherosclerosis
0.000 0.153 0.847
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.161 0.839
I73.8 Other specified peripheral vascular diseases
0.000 0.170 0.830
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.170 0.830
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.170 0.830
I25.5 Ischaemic cardiomyopathy
0.000 0.173 0.827
I71.0 Dissection of aorta [any part]
0.000 0.176 0.824
Chapter IX Diseases of the circulatory system
0.000 0.178 0.822
I77.8 Other specified disorders of arteries and arterioles
0.000 0.191 0.809
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.205 0.795
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.215 0.785
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.223 0.777
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.270 0.730
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.284 0.716
I77.0 Arteriovenous fistula, acquired
0.000 0.284 0.716
I24.8 Other forms of acute ischaemic heart disease
0.000 0.285 0.715
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.288 0.712
I70.1 Atherosclerosis of renal artery
0.000 0.297 0.703
I77.2 Rupture of artery
0.000 0.303 0.697
I23 Certain current complications following acute myocardial infarction
0.000 0.317 0.683
E78.6 Lipoprotein deficiency
0.000 0.329 0.670
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.340 0.660
I20.1 Angina pectoris with documented spasm
0.000 0.340 0.660
I77.5 Necrosis of artery
0.000 0.341 0.659
I77.4 Coeliac artery compression syndrome
0.000 0.341 0.659
I77.3 Arterial fibromuscular dysplasia
0.000 0.341 0.659
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.347 0.653
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.347 0.653
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.347 0.653
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.347 0.653
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.376 0.624
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.391 0.609
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.395 0.605
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.398 0.601
I79.1 Aortitis in diseases classified elsewhere
0.000 0.398 0.601
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.398 0.601
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.401 0.599
I70.0 Atherosclerosis of aorta
0.000 0.409 0.591
I70.9 Generalised and unspecified atherosclerosis
0.000 0.410 0.590
I00-I02 Acute rheumatic fever
0.000 0.411 0.589
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.415 0.584
E78.8 Other disorders of lipoprotein metabolism
0.000 0.416 0.584
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.417 0.583
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.429 0.571
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.439 0.561
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.459 0.541
I70.8 Atherosclerosis of other arteries
0.000 0.465 0.535
I24.1 Dressler's syndrome
0.000 0.469 0.530
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.495 0.505
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.496 0.504
I25.6 Silent myocardial ischaemia
0.001 0.497 0.502
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.497 0.503
I77.6 Arteritis, unspecified
0.000 0.509 0.491
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.510 0.490
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.510 0.490
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.510 0.490
I22.8 Subsequent myocardial infarction of other sites
0.000 0.523 0.476
I97.1 Other functional disturbances following cardiac surgery
0.000 0.539 0.461
I23.8 Other current complications following acute myocardial infarction
0.000 0.544 0.456
I25.3 Aneurysm of heart
0.000 0.546 0.454
I05-I09 Chronic rheumatic heart diseases
0.000 0.560 0.440
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.576 0.423
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.577 0.423
I02 Rheumatic chorea
0.000 0.577 0.423
I01 Rheumatic fever with heart involvement
0.000 0.577 0.423
I00 Rheumatic fever without mention of heart involvement
0.000 0.577 0.423
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.593 0.406
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.595 0.405
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.612 0.388
I97.0 Postcardiotomy syndrome
0.000 0.612 0.388
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.615 0.385
I07 Rheumatic tricuspid valve diseases
0.000 0.615 0.385
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.616 0.383
I74 Arterial embolism and thrombosis
0.000 0.620 0.380
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.621 0.379
I78 Diseases of capillaries
0.000 0.629 0.371
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.650 0.350
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.653 0.347
I07.1 Tricuspid insufficiency
0.000 0.654 0.346
I99 Other and unspecified disorders of circulatory system
0.000 0.657 0.343
I09 Other rheumatic heart diseases
0.000 0.681 0.319
I74.8 Embolism and thrombosis of other arteries
0.000 0.682 0.318
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.682 0.318
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.687 0.313
Z95.1 Presence of aortocoronary bypass graft
0.000 0.688 0.312
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.689 0.311
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.697 0.303
I01.8 Other acute rheumatic heart disease
0.000 0.697 0.303
I01.2 Acute rheumatic myocarditis
0.000 0.697 0.303
I01.1 Acute rheumatic endocarditis
0.000 0.697 0.303
I01.0 Acute rheumatic pericarditis
0.000 0.697 0.303
I02.9 Rheumatic chorea without heart involvement
0.000 0.697 0.303
I02.0 Rheumatic chorea with heart involvement
0.000 0.697 0.303
I05 Rheumatic mitral valve diseases
0.000 0.701 0.299
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.722 0.278
I07.9 Tricuspid valve disease, unspecified
0.000 0.724 0.276
I07.8 Other tricuspid valve diseases
0.000 0.724 0.276
I07.2 Tricuspid stenosis with insufficiency
0.000 0.724 0.276
I07.0 Tricuspid stenosis
0.000 0.724 0.276
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.728 0.272
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.729 0.271
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.732 0.268
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.732 0.268
I78.9 Disease of capillaries, unspecified
0.000 0.734 0.266
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.736 0.264
I05.1 Rheumatic mitral insufficiency
0.000 0.737 0.262
I28 Other diseases of pulmonary vessels
0.000 0.742 0.258
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.742 0.258
Z95.2 Presence of prosthetic heart valve
0.000 0.747 0.253
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.751 0.249
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.751 0.249
I98.0 Cardiovascular syphilis
0.000 0.751 0.249
I06 Rheumatic aortic valve diseases
0.000 0.765 0.234
I09.9 Rheumatic heart disease, unspecified
0.000 0.767 0.232
I09.8 Other specified rheumatic heart diseases
0.000 0.771 0.229
I09.2 Chronic rheumatic pericarditis
0.000 0.771 0.229
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.771 0.229
I09.0 Rheumatic myocarditis
0.000 0.771 0.229
I20.8 Other forms of angina pectoris
0.000 0.772 0.228
I78.8 Other diseases of capillaries
0.000 0.773 0.227
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.780 0.220
I05.8 Other mitral valve diseases
0.000 0.786 0.214
I74.5 Embolism and thrombosis of iliac artery
0.000 0.788 0.212
I05.9 Mitral valve disease, unspecified
0.000 0.790 0.210
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.791 0.208
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.803 0.197
I28.8 Other specified diseases of pulmonary vessels
0.000 0.807 0.192
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.815 0.185
I28.1 Aneurysm of pulmonary artery
0.000 0.815 0.185
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.815 0.185
I26 Pulmonary embolism
0.000 0.815 0.185
I05.0 Mitral stenosis
0.000 0.821 0.179
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.829 0.171
I06.8 Other rheumatic aortic valve diseases
0.000 0.831 0.168
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.831 0.168
I06.1 Rheumatic aortic insufficiency
0.000 0.832 0.168
N90 Other noninflammatory disorders of vulva and perineum
0.000 0.834 0.166
N90.7 Vulvar cyst
0.000 0.838 0.162
N90.4 Leukoplakia of vulva
0.000 0.840 0.160
I72 Other aneurysm
0.001 0.843 0.156
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.000 0.846 0.154
N90.5 Atrophy of vulva
0.000 0.847 0.153
N90.6 Hypertrophy of vulva
0.000 0.848 0.152
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.848 0.152
I05.2 Mitral stenosis with insufficiency
0.000 0.858 0.142
Z95.3 Presence of xenogenic heart valve
0.000 0.860 0.140
I06.0 Rheumatic aortic stenosis
0.001 0.860 0.139
N90.1 Moderate vulvar dysplasia
0.000 0.866 0.134
I10-I15 Hypertensive diseases
0.000 0.867 0.133
I06.9 Rheumatic aortic valve disease, unspecified
0.001 0.867 0.132
I27 Other pulmonary heart diseases
0.000 0.869 0.131
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.000 0.881 0.119
I72.2 Aneurysm of renal artery
0.001 0.881 0.118
N90.0 Mild vulvar dysplasia
0.000 0.884 0.116
I72.9 Aneurysm of unspecified site
0.001 0.885 0.114
I72.6 Aneurysm and dissection of vertebral artery
0.001 0.887 0.112
I72.5 Aneurysm and dissection of other precerebral arteries
0.001 0.887 0.112
I73.0 Raynaud's syndrome
0.000 0.896 0.104
I72.1 Aneurysm of artery of upper extremity
0.001 0.896 0.103
I08 Multiple valve diseases
0.000 0.903 0.097
I11 Hypertensive heart disease
0.000 0.904 0.096
I27.1 Kyphoscoliotic heart disease
0.000 0.906 0.094
I15 Secondary hypertension
0.000 0.908 0.092
I27.9 Pulmonary heart disease, unspecified
0.000 0.908 0.092
I27.8 Other specified pulmonary heart diseases
0.000 0.909 0.091
I72.4 Aneurysm of artery of lower extremity
0.001 0.911 0.089
N90.3 Dysplasia of vulva, unspecified
0.000 0.911 0.088
I08.8 Other multiple valve diseases
0.000 0.911 0.088
I78.1 Naevus, nonneoplastic
0.000 0.914 0.086
I13 Hypertensive heart and renal disease
0.000 0.916 0.084
I95 Hypotension
0.000 0.919 0.081
I72.3 Aneurysm of iliac artery
0.001 0.921 0.078
I08.9 Multiple valve disease, unspecified
0.000 0.923 0.076
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.926 0.074
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.000 0.926 0.074
I15.1 Hypertension secondary to other renal disorders
0.000 0.926 0.073
I15.8 Other secondary hypertension
0.000 0.933 0.066
I15.2 Hypertension secondary to endocrine disorders
0.000 0.933 0.066
I27.0 Primary pulmonary hypertension
0.000 0.935 0.065
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.937 0.063
I72.8 Aneurysm of other specified arteries
0.001 0.937 0.062
I15.0 Renovascular hypertension
0.000 0.939 0.061
I72.0 Aneurysm of carotid artery
0.001 0.939 0.059
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.939 0.060
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.939 0.060
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.939 0.060
I95.8 Other hypotension
0.000 0.940 0.060
I15.9 Seconday hypertension, unspecified
0.000 0.940 0.059
I95.0 Idiopathic hypotension
0.000 0.946 0.054
I27.2 Other secondary pulmonary hypertension
0.000 0.946 0.054
Z95.4 Presence of other heart-valve replacement
0.000 0.947 0.053
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.951 0.049
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.956 0.044
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.958 0.041
I95.1 Orthostatic hypotension
0.000 0.967 0.033
I12 Hypertensive renal disease
0.000 0.967 0.033
I95.2 Hypotension due to drugs
0.000 0.973 0.026
I08.0 Disorders of both mitral and aortic valves
0.000 0.979 0.021
E11.5 With peripheral circulatory complications
0.000 0.979 0.021
E11 Non-insulin-dependent diabetes mellitus
0.000 0.979 0.021
E11.9 Without complications
0.000 0.979 0.021
E11.3 With ophthalmic complications
0.000 0.980 0.020
E11.1 With ketoacidosis
0.000 0.982 0.018
E11.8 With unspecified complications
0.000 0.983 0.017
E11.0 With coma
0.000 0.985 0.015
E11.2 With renal complications
0.000 0.985 0.015
E11.7 With multiple complications
0.000 0.985 0.015
I95.9 Hypotension, unspecified
0.000 0.985 0.015
E11.6 With other specified complications
0.000 0.987 0.013
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.988 0.012
E70-E90 Metabolic disorders
0.000 0.989 0.011
E85 Amyloidosis
0.000 0.990 0.010
E11.4 With neurological complications
0.000 0.990 0.010
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.000 0.990 0.010
I83 Varicose veins of lower extremities
0.000 0.990 0.010
Z95.0 Presence of cardiac pacemaker
0.000 0.990 0.010
E73 Lactose intolerance
0.000 0.990 0.009
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.991 0.009
I81 Portal vein thrombosis
0.000 0.991 0.009
I12.9 Hypertensive renal disease without renal failure
0.000 0.991 0.008
E79 Disorders of purine and pyrimidine metabolism
0.000 0.991 0.009
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.991 0.009
E84 Cystic fibrosis
0.000 0.991 0.009
E85.4 Organ-limited amyloidosis
0.000 0.991 0.008
E73.9 Lactose intolerance, unspecified
0.000 0.992 0.008
E77 Disorders of glycoprotein metabolism
0.000 0.992 0.008
E76 Disorders of glycosaminoglycan metabolism
0.000 0.992 0.008
E72 Other disorders of amino-acid metabolism
0.000 0.992 0.008
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.992 0.008
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.992 0.008
I87 Other disorders of veins
0.000 0.992 0.008
E74 Other disorders of carbohydrate metabolism
0.000 0.992 0.008
C02.1 Border of tongue
0.008 0.992 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.992 0.008
E85.3 Secondary systemic amyloidosis
0.000 0.992 0.008
I88 Nonspecific lymphadenitis
0.000 0.992 0.008
I87.1 Compression of vein
0.000 0.992 0.008
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.992 0.008
C02 Malignant neoplasm of other and unspecified parts of tongue
0.008 0.992 0.000
I85 Oesophageal varices
0.000 0.992 0.008
E70 Disorders of aromatic amino-acid metabolism
0.000 0.992 0.007
E85.9 Amyloidosis, unspecified
0.000 0.993 0.007
E85.8 Other amyloidosis
0.000 0.993 0.007
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.993 0.007
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.993 0.007
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.993 0.007
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.993 0.007
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.993 0.007
I60-I69 Cerebrovascular diseases
0.000 0.993 0.007
E73.8 Other lactose intolerance
0.000 0.993 0.007
E73.1 Secondary lactase deficiency
0.000 0.993 0.007
E73.0 Congenital lactase deficiency
0.000 0.993 0.007
E84.9 Cystic fibrosis, unspecified
0.000 0.993 0.007
M07.30 Other psoriatic arthropathies (Multiple sites)
0.007 0.993 0.000
C02.9 Tongue, unspecified
0.007 0.993 0.000
C00.0 External upper lip
0.007 0.993 0.000
C00 Malignant neoplasm of lip
0.007 0.993 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.993 0.006
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.993 0.006
E79.1 Lesch-Nyhan syndrome
0.000 0.993 0.006
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.007 0.993 0.000
E84.8 Cystic fibrosis with other manifestations
0.000 0.993 0.006
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.993 0.006
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.993 0.006
C06 Malignant neoplasm of other and unspecified parts of mouth
0.006 0.994 0.000
I63 Cerebral infarction
0.000 0.994 0.006
C06.0 Cheek mucosa
0.006 0.994 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.006 0.994 0.000
E71.3 Disorders of fatty-acid metabolism
0.000 0.994 0.006
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.994 0.006
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.994 0.006
E71.0 Maple-syrup-urine disease
0.000 0.994 0.006
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.994 0.006
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.994 0.006
E72.5 Disorders of glycine metabolism
0.000 0.994 0.006
E72.4 Disorders of ornithine metabolism
0.000 0.994 0.006
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.994 0.006
E72.2 Disorders of urea cycle metabolism
0.000 0.994 0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.994 0.006
E72.0 Disorders of amino-acid transport
0.000 0.994 0.006
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.994 0.006
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.994 0.006
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.994 0.006
E76.2 Other mucopolysaccharidoses
0.000 0.994 0.006
E76.1 Mucopolysaccharidosis, type II
0.000 0.994 0.006
E76.0 Mucopolysaccharidosis, type I
0.000 0.994 0.006
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.994 0.006
E77.8 Other disorders of glycoprotein metabolism
0.000 0.994 0.006
E77.1 Defects in glycoprotein degradation
0.000 0.994 0.006
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.994 0.006
I87.9 Disorder of vein, unspecified
0.000 0.994 0.006
I87.0 Postphlebitic syndrome
0.000 0.994 0.006
R16.1 Splenomegaly, not elsewhere classified
0.006 0.994 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.994 0.006
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.994 0.006
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.994 0.006
E74.2 Disorders of galactose metabolism
0.000 0.994 0.006
E74.1 Disorders of fructose metabolism
0.000 0.994 0.006
E74.0 Glycogen storage disease
0.000 0.994 0.006
C02.2 Ventral surface of tongue
0.006 0.994 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.994 0.006
E88 Other metabolic disorders
0.000 0.994 0.006
G50.0 Trigeminal neuralgia
0.000 0.994 0.006
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.994 0.006
E75.6 Lipid storage disorder, unspecified
0.000 0.994 0.006
E75.5 Other lipid storage disorders
0.000 0.994 0.006
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.994 0.006
E75.3 Sphingolipidosis, unspecified
0.000 0.994 0.006
E75.1 Other gangliosidosis
0.000 0.994 0.006
E75.0 GM2 gangliosidosis
0.000 0.994 0.006
C02.8 Overlapping lesion of tongue
0.006 0.994 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.006 0.994 0.000
C02.0 Dorsal surface of tongue
0.006 0.994 0.000
I85.9 Oesophageal varices without bleeding
0.000 0.994 0.006
C07 Malignant neoplasm of parotid gland
0.006 0.994 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.994 0.006
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.994 0.005
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.994 0.005
E70.2 Disorders of tyrosine metabolism
0.000 0.994 0.005
E70.1 Other hyperphenylalaninaemias
0.000 0.994 0.005
E70.0 Classical phenylketonuria
0.000 0.994 0.005
I88.8 Other nonspecific lymphadenitis
0.000 0.994 0.005
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.994 0.005
C02.4 Lingual tonsil
0.006 0.994 0.000
C03 Malignant neoplasm of gum
0.006 0.994 0.000
I87.8 Other specified disorders of veins
0.000 0.994 0.005
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.995 0.005
M07.3 Other psoriatic arthropathies
0.005 0.995 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.995 0.005
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.005 0.995 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.995 0.005
C06.2 Retromolar area
0.005 0.995 0.000
C04 Malignant neoplasm of floor of mouth
0.005 0.995 0.000
C00.9 Lip, unspecified
0.005 0.995 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.995 0.005
E75.2 Other sphingolipidosis
0.000 0.995 0.005
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.995 0.005
C00.1 External lower lip
0.005 0.995 0.000
J36 Peritonsillar abscess
0.005 0.995 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.995 0.005
I63.8 Other cerebral infarction
0.000 0.995 0.005
N85.1 Endometrial adenomatous hyperplasia
0.005 0.995 0.000
C10 Malignant neoplasm of oropharynx
0.005 0.995 0.000
C00.8 Overlapping lesion of lip
0.005 0.995 0.000
C00.6 Commissure of lip
0.005 0.995 0.000
C00.5 Lip, unspecified, inner aspect
0.005 0.995 0.000
C00.4 Lower lip, inner aspect
0.005 0.995 0.000
C00.3 Upper lip, inner aspect
0.005 0.995 0.000
C00.2 External lip, unspecified
0.005 0.995 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.005 0.995 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.995 0.005
C13 Malignant neoplasm of hypopharynx
0.005 0.995 0.000
C11 Malignant neoplasm of nasopharynx
0.005 0.995 0.000
C06.9 Mouth, unspecified
0.005 0.995 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.005 0.995 0.000
C06.1 Vestibule of mouth
0.005 0.995 0.000
E70.3 Albinism
0.000 0.995 0.005
C03.1 Lower gum
0.005 0.995 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.995 0.005
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.995 0.005
I80 Phlebitis and thrombophlebitis
0.000 0.995 0.005
C05 Malignant neoplasm of palate
0.005 0.995 0.000
S20.2 Contusion of thorax
0.005 0.995 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.995 0.005
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.005 0.995 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.995 0.004
K58.0 Irritable bowel syndrome with diarrhoea
0.000 0.995 0.005
I68.0 Cerebral amyloid angiopathy
0.000 0.995 0.004
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.995 0.004
C09 Malignant neoplasm of tonsil
0.004 0.995 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.996 0.004
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.996 0.004
I85.0 Oesophageal varices with bleeding
0.000 0.996 0.004
E88.3 Tumour lysis syndrome
0.000 0.996 0.004
C04.9 Floor of mouth, unspecified
0.004 0.996 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.996 0.004
E88.2 Lipomatosis, not elsewhere classified
0.000 0.996 0.004
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.996 0.004
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.996 0.004
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
M07.34 Other psoriatic arthropathies (Hand)
0.004 0.996 0.000
E80.2 Other porphyria
0.000 0.996 0.004
E88.8 Other specified metabolic disorders
0.000 0.996 0.004
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.996 0.004
C03.9 Gum, unspecified
0.004 0.996 0.000
C03.0 Upper gum
0.004 0.996 0.000
S20 Superficial injury of thorax
0.004 0.996 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.996 0.004
I65.1 Occlusion and stenosis of basilar artery
0.000 0.996 0.004
M07.36 Other psoriatic arthropathies (Lower leg)
0.004 0.996 0.000
M07.38 Other psoriatic arthropathies (Other)
0.004 0.996 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.004 0.996 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.004 0.996 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.004 0.996 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.996 0.004
I62 Other nontraumatic intracranial haemorrhage
0.000 0.996 0.004
C12 Malignant neoplasm of pyriform sinus
0.004 0.996 0.000
W19.4 Street and highway
0.004 0.996 0.000
C04.8 Overlapping lesion of floor of mouth
0.004 0.996 0.000
C04.1 Lateral floor of mouth
0.004 0.996 0.000
C04.0 Anterior floor of mouth
0.004 0.996 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.996 0.004
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.996 0.004
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.004 0.996 0.000
C10.9 Oropharynx, unspecified
0.004 0.996 0.000
E80.5 Crigler-Najjar syndrome
0.000 0.996 0.004
E80.3 Defects of catalase and peroxydase
0.000 0.996 0.004
E80.0 Hereditary erythropoietic porphyria
0.000 0.996 0.004
C08.0 Submandibular gland
0.004 0.996 0.000
C05.0 Hard palate
0.004 0.996 0.000
C10.8 Overlapping lesion of oropharynx
0.004 0.996 0.000
C10.4 Branchial cleft
0.004 0.996 0.000
C10.3 Posterior wall of oropharynx
0.004 0.996 0.000
C10.2 Lateral wall of oropharynx
0.004 0.996 0.000
C10.1 Anterior surface of epiglottis
0.004 0.996 0.000
C10.0 Vallecula
0.004 0.996 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.996 0.004
D13.2 Duodenum
0.000 0.996 0.004
C08.8 Overlapping lesion of major salivary glands
0.004 0.996 0.000
C08.1 Sublingual gland
0.004 0.996 0.000
C13.9 Hypopharynx, unspecified
0.004 0.996 0.000
C13.8 Overlapping lesion of hypopharynx
0.004 0.996 0.000
C13.2 Posterior wall of hypopharynx
0.004 0.996 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.004 0.996 0.000
C13.0 Postcricoid region
0.004 0.996 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.004 0.996 0.000
C01 Malignant neoplasm of base of tongue
0.004 0.996 0.000
S06.2 Diffuse brain injury
0.000 0.996 0.004
C11.8 Overlapping lesion of nasopharynx
0.004 0.996 0.000
C11.3 Anterior wall of nasopharynx
0.004 0.996 0.000
C11.2 Lateral wall of nasopharynx
0.004 0.996 0.000
C11.1 Posterior wall of nasopharynx
0.004 0.996 0.000
C11.0 Superior wall of nasopharynx
0.004 0.996 0.000
C05.1 Soft palate
0.004 0.996 0.000
C05.8 Overlapping lesion of palate
0.004 0.996 0.000
C05.2 Uvula
0.004 0.996 0.000
E80.1 Porphyria cutanea tarda
0.000 0.996 0.003
G91.9 Hydrocephalus, unspecified
0.004 0.996 0.000
C11.9 Nasopharynx, unspecified
0.004 0.996 0.000
C08.9 Major salivary gland, unspecified
0.003 0.996 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.996 0.004
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.996 0.003
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.996 0.003
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.003 0.996 0.000
C14.2 Waldeyer's ring
0.003 0.996 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.996 0.003
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.996 0.004
E80.4 Gilbert's syndrome
0.000 0.996 0.004
I51.9 Heart disease, unspecified
0.000 0.996 0.004
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.996 0.004
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.996 0.003
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.996 0.003
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.996 0.003
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.996 0.003
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.996 0.003
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.996 0.003
C09.8 Overlapping lesion of tonsil
0.003 0.996 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.003 0.996 0.000
C09.0 Tonsillar fossa
0.003 0.996 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.996 0.003
S06.3 Focal brain injury
0.000 0.996 0.003
E10-E14 Diabetes mellitus
0.000 0.997 0.003
N34.2 Other urethritis
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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