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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs645040
log Bayes Factor = 13.7796
Chromosome 3   position 135,926,622  (GRCh37) Explore rs645040 on Ensembl!
Variant rs645040 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.004 0.996
I20 Angina pectoris
0.000 0.021 0.979
I21.4 Acute subendocardial myocardial infarction
0.000 0.021 0.979
I20.9 Angina pectoris, unspecified
0.000 0.041 0.959
I22 Subsequent myocardial infarction
0.000 0.083 0.917
I25.3 Aneurysm of heart
0.000 0.096 0.904
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.105 0.895
I10 Essential (primary) hypertension
0.000 0.105 0.895
I25.5 Ischaemic cardiomyopathy
0.000 0.112 0.888
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.122 0.878
I20.0 Unstable angina
0.000 0.132 0.868
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.201 0.799
I23 Certain current complications following acute myocardial infarction
0.000 0.216 0.784
I24 Other acute ischaemic heart diseases
0.000 0.219 0.781
I20.1 Angina pectoris with documented spasm
0.000 0.240 0.760
I24.8 Other forms of acute ischaemic heart disease
0.000 0.258 0.742
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.307 0.693
I25.4 Coronary artery aneurysm
0.000 0.315 0.685
I10-I15 Hypertensive diseases
0.000 0.335 0.665
I25.6 Silent myocardial ischaemia
0.000 0.368 0.632
I23.8 Other current complications following acute myocardial infarction
0.000 0.371 0.629
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.372 0.628
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.374 0.626
Chapter IX Diseases of the circulatory system
0.000 0.376 0.624
I22.8 Subsequent myocardial infarction of other sites
0.000 0.392 0.607
I24.1 Dressler's syndrome
0.000 0.406 0.594
I25.2 Old myocardial infarction
0.000 0.431 0.569
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.438 0.562
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.438 0.562
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.438 0.562
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.438 0.562
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.438 0.562
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.438 0.562
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.438 0.562
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.449 0.551
I13 Hypertensive heart and renal disease
0.000 0.523 0.477
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.544 0.456
I15 Secondary hypertension
0.000 0.563 0.437
I11 Hypertensive heart disease
0.000 0.569 0.431
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.582 0.418
I00-I02 Acute rheumatic fever
0.000 0.591 0.409
I28 Other diseases of pulmonary vessels
0.000 0.608 0.392
I26 Pulmonary embolism
0.000 0.623 0.377
I20.8 Other forms of angina pectoris
0.000 0.638 0.362
I28.8 Other specified diseases of pulmonary vessels
0.000 0.655 0.345
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.658 0.342
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.658 0.342
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.658 0.342
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.658 0.342
I15.1 Hypertension secondary to other renal disorders
0.000 0.669 0.330
I05-I09 Chronic rheumatic heart diseases
0.000 0.678 0.321
I15.8 Other secondary hypertension
0.000 0.686 0.314
I15.2 Hypertension secondary to endocrine disorders
0.000 0.686 0.314
I15.0 Renovascular hypertension
0.000 0.687 0.313
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.698 0.302
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.704 0.296
I02 Rheumatic chorea
0.000 0.706 0.293
I01 Rheumatic fever with heart involvement
0.000 0.706 0.293
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.708 0.292
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.715 0.284
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.719 0.281
I28.1 Aneurysm of pulmonary artery
0.000 0.719 0.281
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.719 0.281
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.727 0.273
I00 Rheumatic fever without mention of heart involvement
0.000 0.745 0.255
I70 Atherosclerosis
0.000 0.749 0.251
I15.9 Seconday hypertension, unspecified
0.000 0.751 0.249
I50 Heart failure
0.000 0.762 0.238
I50.1 Left ventricular failure
0.000 0.767 0.233
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.769 0.231
I30-I52 Other forms of heart disease
0.000 0.769 0.231
I09 Other rheumatic heart diseases
0.000 0.771 0.229
I50.0 Congestive heart failure
0.000 0.777 0.223
I07 Rheumatic tricuspid valve diseases
0.000 0.778 0.222
I06 Rheumatic aortic valve diseases
0.000 0.779 0.221
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.782 0.218
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.789 0.210
I01.8 Other acute rheumatic heart disease
0.000 0.789 0.210
I01.2 Acute rheumatic myocarditis
0.000 0.789 0.210
I01.1 Acute rheumatic endocarditis
0.000 0.789 0.210
I01.0 Acute rheumatic pericarditis
0.000 0.789 0.210
I02.9 Rheumatic chorea without heart involvement
0.000 0.789 0.210
I02.0 Rheumatic chorea with heart involvement
0.000 0.789 0.210
I45 Other conduction disorders
0.000 0.792 0.208
I72 Other aneurysm
0.000 0.793 0.207
I70.0 Atherosclerosis of aorta
0.000 0.794 0.206
I08 Multiple valve diseases
0.000 0.794 0.206
I45.6 Preexcitation syndrome
0.000 0.798 0.202
I73 Other peripheral vascular diseases
0.000 0.800 0.200
I50.9 Heart failure, unspecified
0.000 0.801 0.199
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.802 0.198
I74 Arterial embolism and thrombosis
0.000 0.804 0.196
I70.1 Atherosclerosis of renal artery
0.000 0.806 0.194
I36 Nonrheumatic tricuspid valve disorders
0.000 0.807 0.193
I45.3 Trifascicular block
0.000 0.809 0.191
I33 Acute and subacute endocarditis
0.000 0.811 0.189
I99 Other and unspecified disorders of circulatory system
0.000 0.814 0.186
I05 Rheumatic mitral valve diseases
0.000 0.817 0.183
I08.8 Other multiple valve diseases
0.000 0.817 0.183
I70.8 Atherosclerosis of other arteries
0.000 0.818 0.182
I31 Other diseases of pericardium
0.000 0.818 0.182
I73.9 Peripheral vascular disease, unspecified
0.000 0.819 0.181
I70.9 Generalised and unspecified atherosclerosis
0.000 0.820 0.180
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.826 0.174
I45.4 Nonspecific intraventricular block
0.000 0.826 0.174
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.830 0.170
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.833 0.167
I72.3 Aneurysm of iliac artery
0.000 0.834 0.166
I45.8 Other specified conduction disorders
0.000 0.834 0.166
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.834 0.166
I52 Other heart disorders in diseases classified elsewhere
0.000 0.834 0.166
I48 Atrial fibrillation and flutter
0.000 0.834 0.166
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.834 0.166
I41 Myocarditis in diseases classified elsewhere
0.000 0.834 0.166
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.834 0.166
I32 Pericarditis in diseases classified elsewhere
0.000 0.834 0.166
I77 Other disorders of arteries and arterioles
0.000 0.835 0.165
I09.8 Other specified rheumatic heart diseases
0.000 0.836 0.164
I09.2 Chronic rheumatic pericarditis
0.000 0.836 0.164
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.836 0.164
I09.0 Rheumatic myocarditis
0.000 0.836 0.164
I72.0 Aneurysm of carotid artery
0.000 0.836 0.164
I09.9 Rheumatic heart disease, unspecified
0.000 0.837 0.163
I31.3 Pericardial effusion (noninflammatory)
0.000 0.839 0.161
I07.9 Tricuspid valve disease, unspecified
0.000 0.840 0.159
I07.8 Other tricuspid valve diseases
0.000 0.840 0.159
I07.2 Tricuspid stenosis with insufficiency
0.000 0.840 0.159
I07.0 Tricuspid stenosis
0.000 0.840 0.159
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.840 0.160
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.841 0.159
I40 Acute myocarditis
0.000 0.841 0.159
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.841 0.158
I06.8 Other rheumatic aortic valve diseases
0.000 0.841 0.158
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.841 0.158
I06.1 Rheumatic aortic insufficiency
0.000 0.841 0.158
I33.0 Acute and subacute infective endocarditis
0.000 0.841 0.158
I12 Hypertensive renal disease
0.000 0.842 0.158
I30 Acute pericarditis
0.000 0.843 0.156
I77.1 Stricture of artery
0.000 0.844 0.156
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.846 0.154
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.846 0.154
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.847 0.153
I07.1 Tricuspid insufficiency
0.000 0.849 0.151
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.849 0.151
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.850 0.150
I45.0 Right fascicular block
0.000 0.850 0.149
I06.0 Rheumatic aortic stenosis
0.000 0.851 0.148
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.851 0.148
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.851 0.148
I72.1 Aneurysm of artery of upper extremity
0.000 0.851 0.148
I72.8 Aneurysm of other specified arteries
0.000 0.851 0.148
I47 Paroxysmal tachycardia
0.000 0.852 0.148
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.852 0.148
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.853 0.147
I73.8 Other specified peripheral vascular diseases
0.000 0.853 0.147
I05.2 Mitral stenosis with insufficiency
0.000 0.857 0.143
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.857 0.143
I31.0 Chronic adhesive pericarditis
0.000 0.858 0.142
I37 Pulmonary valve disorders
0.000 0.858 0.142
I08.9 Multiple valve disease, unspecified
0.000 0.858 0.142
I72.2 Aneurysm of renal artery
0.000 0.859 0.141
I46 Cardiac arrest
0.000 0.860 0.140
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.860 0.139
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.861 0.139
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.861 0.139
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.861 0.139
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.861 0.139
I24.9 Acute ischaemic heart disease, unspecified
0.001 0.861 0.138
I72.4 Aneurysm of artery of lower extremity
0.000 0.861 0.139
I72.9 Aneurysm of unspecified site
0.000 0.863 0.137
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.864 0.136
I33.9 Acute endocarditis, unspecified
0.000 0.864 0.135
I05.1 Rheumatic mitral insufficiency
0.000 0.865 0.135
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.866 0.134
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.868 0.132
I05.8 Other mitral valve diseases
0.000 0.869 0.131
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.869 0.130
I31.8 Other specified diseases of pericardium
0.000 0.870 0.130
I31.2 Haemopericardium, not elsewhere classified
0.000 0.870 0.130
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.870 0.130
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.871 0.129
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.871 0.129
I97.1 Other functional disturbances following cardiac surgery
0.000 0.873 0.127
I77.2 Rupture of artery
0.000 0.874 0.126
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.875 0.125
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.877 0.123
I77.8 Other specified disorders of arteries and arterioles
0.000 0.879 0.121
I74.8 Embolism and thrombosis of other arteries
0.000 0.880 0.120
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.881 0.119
I47.2 Ventricular tachycardia
0.000 0.881 0.119
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.881 0.119
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.881 0.119
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.881 0.119
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.881 0.119
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.881 0.119
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.881 0.119
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.881 0.119
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.881 0.119
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.881 0.119
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.881 0.119
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.881 0.119
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.881 0.119
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.881 0.119
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.881 0.119
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.881 0.119
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.881 0.119
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.881 0.119
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.881 0.119
I48.4 Atypical atrial flutter
0.000 0.881 0.119
I48.3 Typical atrial flutter
0.000 0.881 0.119
I48.2 Chronic atrial fibrillation
0.000 0.881 0.119
I48.1 Persistent atrial fibrillation
0.000 0.881 0.119
I48.0 Paroxysmal atrial fibrillation
0.000 0.881 0.119
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.881 0.119
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.881 0.119
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.881 0.119
I31.1 Chronic constrictive pericarditis
0.000 0.881 0.119
I77.5 Necrosis of artery
0.000 0.881 0.118
I77.4 Coeliac artery compression syndrome
0.000 0.881 0.118
I77.3 Arterial fibromuscular dysplasia
0.000 0.881 0.118
I45.5 Other specified heart block
0.000 0.884 0.116
C85.1 B-cell lymphoma, unspecified
0.116 0.884 0.000
I79.1 Aortitis in diseases classified elsewhere
0.000 0.885 0.114
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.885 0.114
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.885 0.114
I97.0 Postcardiotomy syndrome
0.000 0.885 0.114
I40.9 Acute myocarditis, unspecified
0.000 0.886 0.114
I40.8 Other acute myocarditis
0.000 0.886 0.114
I40.1 Isolated myocarditis
0.000 0.886 0.114
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.114 0.886 0.000
I05.0 Mitral stenosis
0.000 0.887 0.113
E78.0 Pure hypercholesterolaemia
0.000 0.887 0.113
I30.8 Other forms of acute pericarditis
0.000 0.888 0.112
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.888 0.112
C91.1 Chronic lymphocytic leukaemia
0.112 0.888 0.000
I30.9 Acute pericarditis, unspecified
0.000 0.888 0.112
C91 Lymphoid leukaemia
0.108 0.892 0.000
I40.0 Infective myocarditis
0.000 0.892 0.108
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.107 0.893 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.107 0.893 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.894 0.105
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.895 0.104
I30.1 Infective pericarditis
0.000 0.896 0.104
I78 Diseases of capillaries
0.000 0.897 0.103
I37.9 Pulmonary valve disorder, unspecified
0.000 0.898 0.102
I37.8 Other pulmonary valve disorders
0.000 0.898 0.102
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.898 0.102
I37.0 Pulmonary valve stenosis
0.000 0.898 0.102
I46.1 Sudden cardiac death, so described
0.000 0.899 0.100
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.900 0.100
I46.0 Cardiac arrest with successful resuscitation
0.000 0.902 0.098
I47.0 Reentry ventricular arrhythmia
0.000 0.904 0.096
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.095 0.905 0.000
I34 Nonrheumatic mitral valve disorders
0.000 0.907 0.093
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.908 0.092
C90 Multiple myeloma and malignant plasma cell neoplasms
0.092 0.908 0.000
C91.9 Lymphoid leukaemia, unspecified
0.092 0.908 0.000
I74.5 Embolism and thrombosis of iliac artery
0.000 0.909 0.091
C95 Leukaemia of unspecified cell type
0.089 0.911 0.000
I77.0 Arteriovenous fistula, acquired
0.000 0.911 0.088
I31.9 Disease of pericardium, unspecified
0.000 0.914 0.086
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.914 0.086
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.914 0.086
I98.0 Cardiovascular syphilis
0.000 0.914 0.086
I45.9 Conduction disorder, unspecified
0.000 0.915 0.085
C82.0 Small cleaved cell, follicular
0.084 0.916 0.000
C91.5 Adult T-cell leukaemia
0.083 0.916 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.082 0.918 0.000
C85.0 Lymphosarcoma
0.082 0.918 0.000
C81 Hodgkin's disease
0.080 0.920 0.000
I05.9 Mitral valve disease, unspecified
0.000 0.920 0.079
I46.9 Cardiac arrest, unspecified
0.000 0.921 0.079
C90.3 Solitary plasmacytoma
0.079 0.921 0.000
I37.1 Pulmonary valve insufficiency
0.000 0.922 0.078
C91.8 Mature B-cell leukaemia Burkitt-type
0.078 0.922 0.000
C91.7 Other lymphoid leukaemia
0.078 0.922 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.078 0.922 0.000
C91.3 Prolymphocytic leukaemia
0.078 0.922 0.000
C91.2 Subacute lymphocytic leukaemia
0.078 0.922 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.923 0.077
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.077 0.923 0.000
C94 Other leukaemias of specified cell type
0.077 0.923 0.000
C86 Other specified types of T/NK-cell lymphoma
0.077 0.923 0.000
C93 Monocytic leukaemia
0.077 0.923 0.000
I45.2 Bifascicular block
0.001 0.924 0.075
I49 Other cardiac arrhythmias
0.000 0.925 0.075
C82.2 Large cell, follicular
0.075 0.925 0.000
I78.9 Disease of capillaries, unspecified
0.000 0.926 0.074
C88 Malignant immunoproliferative diseases
0.074 0.926 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.073 0.927 0.000
C95.9 Leukaemia, unspecified
0.071 0.929 0.000
C90.0 Multiple myeloma
0.071 0.929 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.071 0.929 0.000
I51 Complications and ill-defined descriptions of heart disease
0.000 0.929 0.071
C95.1 Chronic leukaemia of unspecified cell type
0.070 0.930 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.930 0.070
C90.1 Plasma cell leukaemia
0.070 0.930 0.000
I45.1 Other and unspecified right bundle-branch block
0.000 0.931 0.069
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.931 0.069
C82.6 Cutaneous follicle centre lymphoma
0.068 0.932 0.000
C82.5 Diffuse follicle centre lymphoma
0.068 0.932 0.000
C82.4 Follicular lymphoma grade IIIb
0.068 0.932 0.000
I35 Nonrheumatic aortic valve disorders
0.000 0.932 0.068
C91.0 Acute lymphoblastic leukaemia
0.067 0.932 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.933 0.066
I27 Other pulmonary heart diseases
0.001 0.934 0.065
I49.1 Atrial premature depolarisation
0.000 0.935 0.065
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.065 0.935 0.000
C81.2 Mixed cellularity
0.064 0.936 0.000
C95.7 Other leukaemia of unspecified cell type
0.064 0.936 0.000
C95.2 Subacute leukaemia of unspecified cell type
0.064 0.936 0.000
C95.0 Acute leukaemia of unspecified cell type
0.064 0.936 0.000
I78.8 Other diseases of capillaries
0.000 0.937 0.063
C90.2 Plasmacytoma, extramedullary
0.063 0.937 0.000
C81.7 Other Hodgkin's disease
0.063 0.937 0.000
I49.4 Other and unspecified premature depolarisation
0.000 0.937 0.063
C82.3 Follicular lymphoma grade IIIa
0.062 0.938 0.000
C81.0 Lymphocytic predominance
0.062 0.938 0.000
I49.5 Sick sinus syndrome
0.000 0.938 0.062
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.939 0.061
C81.9 Hodgkin's disease, unspecified
0.059 0.941 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.058 0.942 0.000
C81.3 Lymphocytic depletion
0.058 0.942 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.057 0.943 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.943 0.056
C84 Peripheral and cutaneous T-cell lymphomas
0.056 0.944 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.056 0.944 0.000
C91.4 Hairy-cell leukaemia
0.056 0.944 0.000
I51.4 Myocarditis, unspecified
0.000 0.944 0.056
I51.9 Heart disease, unspecified
0.000 0.944 0.056
I35.9 Aortic valve disorder, unspecified
0.000 0.945 0.055
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.055 0.945 0.000
C86.5 Angioimmunoblastic T-cell lymphoma
0.055 0.945 0.000
C86.4 Blastic NK-cell lymphoma
0.055 0.945 0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.055 0.945 0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.055 0.945 0.000
C86.1 Hepatosplenic T-cell lymphoma
0.055 0.945 0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.055 0.945 0.000
C94.7 Other specified leukaemias
0.055 0.945 0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.055 0.945 0.000
C94.5 Acute myelofibrosis
0.055 0.945 0.000
C94.4 Acute panmyelosis
0.055 0.945 0.000
C94.3 Mast cell leukaemia
0.055 0.945 0.000
C94.2 Acute megakaryoblastic leukaemia
0.055 0.945 0.000
C94.1 Chronic erythraemia
0.055 0.945 0.000
C94.0 Acute erythraemia and erythroleukaemia
0.055 0.945 0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.055 0.945 0.000
C96.8 Histiocytic sarcoma
0.055 0.945 0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.055 0.945 0.000
C96.6 Unifocal Langerhans-cell histiocytosis
0.055 0.945 0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.055 0.945 0.000
C96.4 Sarcoma of dendritic cells (accessory cells)
0.055 0.945 0.000
C96.3 True histiocytic lymphoma
0.055 0.945 0.000
C96.2 Malignant mast cell tumour
0.055 0.945 0.000
C96.1 Malignant histiocytosis
0.055 0.945 0.000
C96.0 Letterer-Siwe disease
0.055 0.945 0.000
C93.9 Monocytic leukaemia, unspecified
0.055 0.945 0.000
C93.7 Other monocytic leukaemia
0.055 0.945 0.000
C93.3 Juvenile myelomonocytic leukaemia
0.055 0.945 0.000
C93.2 Subacute monocytic leukaemia
0.055 0.945 0.000
C93.0 Acute monocytic leukaemia
0.055 0.945 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.945 0.055
C93.1 Chronic monocytic leukaemia
0.055 0.945 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.945 0.055
I49.2 Junctional premature depolarisation
0.000 0.946 0.054
C88.9 Malignant immunoproliferative disease, unspecified
0.053 0.947 0.000
C88.7 Other malignant immunoproliferative diseases
0.053 0.947 0.000
C88.3 Immunoproliferative small intestinal disease
0.053 0.947 0.000
C88.2 Gamma heavy chain disease
0.053 0.947 0.000
C88.1 Alpha heavy chain disease
0.053 0.947 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.948 0.052
I51.5 Myocardial degeneration
0.000 0.949 0.051
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.949 0.051
I51.0 Cardiac septal defect, acquired
0.000 0.951 0.049
I27.8 Other specified pulmonary heart diseases
0.001 0.952 0.048
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.953 0.047
I27.1 Kyphoscoliotic heart disease
0.001 0.953 0.047
C88.0 Waldenstrom's macroglobulinaemia
0.046 0.954 0.000
I38 Endocarditis, valve unspecified
0.000 0.954 0.046
I44 Atrioventricular and left bundle-branch block
0.000 0.954 0.046
I34.0 Mitral (valve) insufficiency
0.000 0.956 0.044
I12.9 Hypertensive renal disease without renal failure
0.001 0.958 0.042
C84.0 Mycosis fungoides
0.042 0.958 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.042 0.958 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.958 0.042
I51.6 Cardiovascular disease, unspecified
0.000 0.958 0.041
C84.8 Cutaneous T-cell lymphoma, unspecified
0.041 0.959 0.000
I78.1 Naevus, nonneoplastic
0.000 0.959 0.041
C84.9 Mature T/NK-cell lymphoma, unspecified
0.040 0.959 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.040 0.959 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.040 0.959 0.000
C84.3 Lymphoepithelioid lymphoma
0.040 0.959 0.000
C84.2 T-zone lymphoma
0.040 0.959 0.000
C84.1 Sezary's diease
0.040 0.959 0.000
I35.8 Other aortic valve disorders
0.000 0.960 0.040
I44.2 Atrioventricular block, complete
0.000 0.960 0.040
I77.6 Arteritis, unspecified
0.001 0.961 0.038
C92 Myeloid leukaemia
0.038 0.962 0.000
C81.1 Nodular sclerosis
0.038 0.962 0.000
I44.6 Other and unspecified fascicular block
0.000 0.963 0.037
I73.0 Raynaud's syndrome
0.000 0.966 0.034
I47.1 Supraventricular tachycardia
0.000 0.966 0.034
I71 Aortic aneurysm and dissection
0.001 0.966 0.033
E78.1 Pure hyperglyceridaemia
0.000 0.966 0.034
C83.0 Small cell (diffuse)
0.033 0.967 0.000
I44.5 Left posterior fascicular block
0.000 0.967 0.033
C84.5 Other and unspecified T-cell lymphomas
0.032 0.968 0.000
I44.4 Left anterior fascicular block
0.000 0.968 0.032
E78.2 Mixed hyperlipidaemia
0.000 0.969 0.031
I49.0 Ventricular fibrillation and flutter
0.000 0.969 0.031
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.031 0.969 0.000
E78.4 Other hyperlipidaemia
0.000 0.969 0.031
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.969 0.031
C83.6 Undifferentiated (diffuse)
0.030 0.970 0.000
C83.5 Lymphoblastic (diffuse)
0.030 0.970 0.000
C83.4 Immunoblastic (diffuse)
0.030 0.970 0.000
C83.2 Mixed small and large cell (diffuse)
0.030 0.970 0.000
C92.4 Acute promyelocytic leukaemia
0.030 0.970 0.000
E78.3 Hyperchylomicronaemia
0.000 0.970 0.030
C84.4 Peripheral T-cell lymphoma
0.029 0.970 0.000
C83.7 Burkitt's tumour
0.028 0.972 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.972 0.028
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.027 0.972 0.000
C92.7 Other myeloid leukaemia
0.027 0.972 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.027 0.972 0.000
C92.5 Acute myelomonocytic leukaemia
0.027 0.972 0.000
C92.3 Myeloid sarcoma
0.027 0.972 0.000
C92.2 Subacute myeloid leukaemia
0.027 0.972 0.000
Z43.2 Attention to ileostomy
0.028 0.972 0.000
I08.0 Disorders of both mitral and aortic valves
0.000 0.973 0.027
E78.6 Lipoprotein deficiency
0.000 0.973 0.027
C92.9 Myeloid leukaemia, unspecified
0.027 0.973 0.000
I44.3 Other and unspecified atrioventricular block
0.000 0.973 0.027
E78.8 Other disorders of lipoprotein metabolism
0.000 0.973 0.027
C83.1 Small cleaved cell (diffuse)
0.026 0.973 0.000
I34.1 Mitral (valve) prolapse
0.000 0.974 0.026
I51.7 Cardiomegaly
0.000 0.975 0.025
E78.5 Hyperlipidaemia, unspecified
0.000 0.975 0.025
I71.8 Aortic aneurysm of unspecified site, ruptured
0.001 0.975 0.024
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.001 0.975 0.024
I71.1 Thoracic aortic aneurysm, ruptured
0.001 0.975 0.024
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.001 0.976 0.024
I42 Cardiomyopathy
0.000 0.976 0.024
I27.9 Pulmonary heart disease, unspecified
0.001 0.976 0.023
I51.8 Other ill-defined heart diseases
0.000 0.976 0.024
I49.3 Ventricular premature depolarisation
0.000 0.976 0.023
I49.8 Other specified cardiac arrhythmias
0.000 0.977 0.023
I27.0 Primary pulmonary hypertension
0.000 0.978 0.022
Z50.0 Cardiac rehabilitation
0.000 0.978 0.022
I49.9 Cardiac arrhythmia, unspecified
0.000 0.979 0.021
M41.99 Scoliosis, unspecified (Site unspecified)
0.020 0.980 0.000
C83.3 Large cell (diffuse)
0.020 0.980 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.020 0.980 0.000
B18 Chronic viral hepatitis
0.020 0.980 0.000
B15-B19 Viral hepatitis
0.019 0.980 0.000
I44.1 Atrioventricular block, second degree
0.000 0.981 0.019
B17.1 Acute hepatitis C
0.019 0.981 0.000
B17 Other acute viral hepatitis
0.019 0.981 0.000
B19 Unspecified viral hepatitis
0.018 0.982 0.000
C92.1 Chronic myeloid leukaemia
0.018 0.982 0.000
B18.1 Chronic viral hepatitis B without delta-agent
0.018 0.982 0.000
B18.2 Chronic viral hepatitis C
0.018 0.982 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.982 0.018
B19.9 Unspecified viral hepatitis without coma
0.018 0.982 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.000 0.982 0.018
I42.5 Other restrictive cardiomyopathy
0.000 0.982 0.017
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.982 0.017
I71.3 Abdominal aortic aneurysm, ruptured
0.001 0.983 0.017
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.983 0.017
B15 Acute hepatitis A
0.016 0.983 0.000
I60-I69 Cerebrovascular diseases
0.000 0.984 0.016
I61 Intracerebral haemorrhage
0.000 0.984 0.016
I42.4 Endocardial fibroelastosis
0.000 0.984 0.016
I42.6 Alcoholic cardiomyopathy
0.000 0.984 0.016
I42.9 Cardiomyopathy, unspecified
0.000 0.984 0.016
B16 Acute hepatitis B
0.015 0.985 0.000
I61.8 Other intracerebral haemorrhage
0.000 0.985 0.015
I42.8 Other cardiomyopathies
0.000 0.985 0.015
B15.9 Hepatitis A without hepatic coma
0.014 0.986 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.000 0.986 0.014
M41.9 Scoliosis, unspecified
0.014 0.986 0.000
B18.9 Chronic viral hepatitis, unspecified
0.014 0.986 0.000
B18.8 Other chronic viral hepatitis
0.014 0.986 0.000
B18.0 Chronic viral hepatitis B with delta-agent
0.014 0.986 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.986 0.014
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.986 0.014
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.986 0.014
I42.0 Dilated cardiomyopathy
0.000 0.986 0.014
B17.9 Acute viral hepatitis, unspecified
0.014 0.986 0.000
B17.8 Other specified acute viral hepatitis
0.014 0.986 0.000
B17.2 Acute hepatitis E
0.014 0.986 0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier
0.014 0.986 0.000
B19.0 Unspecified viral hepatitis with coma
0.013 0.987 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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