TreeWAS – Variant ID: rs12986171

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25.2 Old myocardial infarction	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000	0.000
Z95 Presence of cardiac and vascular implants and grafts	1.000	0.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000	0.000
I21 Acute myocardial infarction	1.000	0.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.999	0.001	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.998	0.002	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.998	0.002	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.997	0.003	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.995	0.005	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.995	0.005	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.994	0.006	0.000
I50 Heart failure	0.994	0.006	0.000
Z71.8 Other specified counselling	0.993	0.007	0.000
I50.9 Heart failure, unspecified	0.992	0.008	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.991	0.009	0.000
I51 Complications and ill-defined descriptions of heart disease	0.991	0.009	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.987	0.013	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.979	0.021	0.000
Z36 Antenatal screening	0.971	0.029	0.000
# Top node	0.969	0.031	0.000
Z95.1 Presence of aortocoronary bypass graft	0.969	0.031	0.000
Z37 Outcome of delivery	0.969	0.031	0.000
Chapter X Diseases of the respiratory system	0.968	0.032	0.000
Chapter VI Diseases of the nervous system	0.965	0.035	0.000
G90-G99 Other disorders of the nervous system	0.965	0.035	0.000
I22 Subsequent myocardial infarction	0.964	0.036	0.000
J90-J94 Other diseases of pleura	0.963	0.037	0.000
J93 Pneumothorax	0.959	0.041	0.000
I51.7 Cardiomegaly	0.958	0.042	0.000
Z37.2 Twins, both liveborn	0.957	0.043	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.947	0.053	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.947	0.053	0.000
G95 Other diseases of spinal cord	0.946	0.054	0.000
I45 Other conduction disorders	0.945	0.055	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.944	0.056	0.000
Z95.0 Presence of cardiac pacemaker	0.943	0.057	0.000
J93.9 Pneumothorax, unspecified	0.942	0.058	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.942	0.058	0.000
I51.9 Heart disease, unspecified	0.941	0.059	0.000
J40-J47 Chronic lower respiratory diseases	0.937	0.063	0.000
J43 Emphysema	0.937	0.063	0.000
J43.9 Emphysema, unspecified	0.934	0.066	0.000
I45.1 Other and unspecified right bundle-branch block	0.930	0.070	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.928	0.072	0.000
Z36.9 Antenatal screening, unspecified	0.925	0.075	0.000
Z74 Problems related to care-provider dependency	0.914	0.086	0.000
I46 Cardiac arrest	0.912	0.088	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.911	0.089	0.000
Z89 Acquired absence of limb	0.910	0.090	0.000
I25.5 Ischaemic cardiomyopathy	0.908	0.092	0.000
I35 Nonrheumatic aortic valve disorders	0.908	0.092	0.000
Z83 Family history of other specific disorders	0.907	0.093	0.000
Z94 Transplanted organ and tissue status	0.904	0.096	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.896	0.104	0.000
Z95.4 Presence of other heart-valve replacement	0.894	0.106	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.892	0.108	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.890	0.110	0.000
Z39 Postpartum care and examination	0.889	0.111	0.000
G95.1 Vascular myelopathies	0.888	0.112	0.000
Z95.2 Presence of prosthetic heart valve	0.886	0.114	0.000
Z83.3 Family history of diabetes mellitus	0.884	0.116	0.000
J95-J99 Other diseases of the respiratory system	0.884	0.116	0.000
J93.1 Other spontaneous pneumothorax	0.884	0.116	0.000
I71 Aortic aneurysm and dissection	0.882	0.118	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.881	0.119	0.000
I20 Angina pectoris	0.866	0.134	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.865	0.135	0.000
Z22 Carrier of infectious disease	0.865	0.135	0.000
J92 Pleural plaque	0.864	0.136	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.860	0.140	0.000
Z29 Need for other prophylactic measures	0.855	0.145	0.000
J95.8 Other postprocedural respiratory disorders	0.851	0.149	0.000
I44 Atrioventricular and left bundle-branch block	0.845	0.155	0.000
Z39.0 Care and examination immediately after delivery	0.838	0.162	0.000
I51.6 Cardiovascular disease, unspecified	0.838	0.162	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.836	0.164	0.000
I20.0 Unstable angina	0.833	0.167	0.000
G95.2 Cord compression, unspecified	0.831	0.169	0.000
I46.9 Cardiac arrest, unspecified	0.827	0.173	0.000
I37 Pulmonary valve disorders	0.825	0.175	0.000
Z74.0 Reduced mobility	0.823	0.177	0.000
J94 Other pleural conditions	0.821	0.179	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.819	0.181	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.817	0.182	0.000
I78 Diseases of capillaries	0.811	0.189	0.000
Z22.3 Carrier of other specified bacterial diseases	0.810	0.190	0.000
I44.0 Atrioventricular block, first degree	0.809	0.191	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.809	0.191	0.000
I24 Other acute ischaemic heart diseases	0.809	0.191	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.808	0.192	0.000
Z94.7 Corneal transplant status	0.808	0.192	0.000
Z57 Occupational exposure to risk-factors	0.806	0.194	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.803	0.197	0.000
G40-G47 Episodic and paroxysmal disorders	0.803	0.197	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.800	0.200	0.000
I05-I09 Chronic rheumatic heart diseases	0.798	0.202	0.000
I45.4 Nonspecific intraventricular block	0.797	0.203	0.000
I21.9 Acute myocardial infarction, unspecified	0.795	0.205	0.000
Z36.8 Other antenatal screening	0.794	0.206	0.000
J43.8 Other emphysema	0.785	0.215	0.000
G90 Disorders of autonomic nervous system	0.784	0.216	0.000
I74 Arterial embolism and thrombosis	0.784	0.216	0.000
Z34 Supervision of normal pregnancy	0.784	0.216	0.000
Z29.0 Isolation	0.784	0.216	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.783	0.217	0.000
I35.0 Aortic (valve) stenosis	0.778	0.222	0.000
Z35 Supervision of high-risk pregnancy	0.777	0.223	0.000
Z98 Other postsurgical states	0.776	0.224	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.776	0.224	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.773	0.227	0.000
Z94.4 Liver transplant status	0.772	0.228	0.000
Z75 Problems related to medical facilities and other health care	0.771	0.229	0.000
I31 Other diseases of pericardium	0.770	0.230	0.000
Z31 Procreative management	0.769	0.231	0.000
Chapter XXII Codes for special purposes	0.768	0.232	0.000
J93.8 Other pneumothorax	0.763	0.237	0.000
I45.8 Other specified conduction disorders	0.760	0.240	0.000
Z89.6 Acquired absence of leg above knee	0.759	0.241	0.000
Z38 Liveborn infants according to place of birth	0.759	0.241	0.000
J44 Other chronic obstructive pulmonary disease	0.757	0.243	0.000
Z76 Persons encountering health services in other circumstances	0.757	0.243	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.756	0.244	0.000
J92.9 Pleural plaque without asbestos	0.755	0.245	0.000
Z63 Other problems related to primary support group, including family circumstances	0.754	0.246	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.754	0.246	0.000
Z95.3 Presence of xenogenic heart valve	0.754	0.246	0.000
Z98.1 Arthrodesis status	0.752	0.248	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.749	0.251	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.747	0.253	0.000
Z99.8 Dependence on other enabling machines and devices	0.746	0.254	0.000
Z73 Problems related to life-management difficulty	0.744	0.256	0.000
I77 Other disorders of arteries and arterioles	0.743	0.257	0.000
Z37.1 Single stillbirth	0.742	0.258	0.000
I33 Acute and subacute endocarditis	0.742	0.258	0.000
I30 Acute pericarditis	0.740	0.260	0.000
J93.0 Spontaneous tension pneumothorax	0.739	0.261	0.000
Z71.6 Tobacco abuse counselling	0.739	0.261	0.000
Z83.6 Family history of diseases of the respiratory system	0.736	0.264	0.000
I50.1 Left ventricular failure	0.734	0.266	0.000
G95.8 Other specified diseases of spinal cord	0.732	0.268	0.000
Z29.2 Other prophylactic chemotherapy	0.731	0.269	0.000
Z99.1 Dependence on respirator	0.730	0.270	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.730	0.270	0.000
J43.2 Centrilobular emphysema	0.725	0.275	0.000
G95.9 Disease of spinal cord, unspecified	0.725	0.275	0.000
I36 Nonrheumatic tricuspid valve disorders	0.725	0.275	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.725	0.275	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.723	0.277	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.723	0.277	0.000
I46.0 Cardiac arrest with successful resuscitation	0.721	0.279	0.000
Z71.3 Dietary counselling and surveillance	0.718	0.282	0.000
I45.2 Bifascicular block	0.718	0.282	0.000
I07 Rheumatic tricuspid valve diseases	0.718	0.282	0.000
G95.0 Syringomyelia and syringobulbia	0.718	0.282	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.717	0.283	0.000
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283	0.000
I48 Atrial fibrillation and flutter	0.717	0.283	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283	0.000
I41 Myocarditis in diseases classified elsewhere	0.717	0.283	0.000
I40 Acute myocarditis	0.717	0.283	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283	0.000
I32 Pericarditis in diseases classified elsewhere	0.717	0.283	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.716	0.284	0.000
Z89.2 Acquired absence of upper limb above wrist	0.716	0.284	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.715	0.284	0.000
Z82.2 Family history of deafness and hearing loss	0.715	0.284	0.000
Z82.1 Family history of blindness and visual loss	0.715	0.284	0.000
Z58 Problems related to physical environment	0.714	0.286	0.000
I71.0 Dissection of aorta [any part]	0.714	0.286	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.713	0.287	0.000
Z71.5 Drug abuse counselling and surveillance	0.713	0.287	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.713	0.287	0.000
Z71.0 Person consulting on behalf of another person	0.713	0.287	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.713	0.287	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.712	0.288	0.000
G70-G73 Diseases of myoneural junction and muscle	0.711	0.288	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.711	0.289	0.000
J00-J06 Acute upper respiratory infections	0.711	0.289	0.000
I51.5 Myocardial degeneration	0.710	0.290	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.710	0.290	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.710	0.290	0.000
I51.0 Cardiac septal defect, acquired	0.710	0.290	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.709	0.291	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.707	0.293	0.000
J92.0 Pleural plaque with presence of asbestos	0.706	0.294	0.000
Z57.2 Occupational exposure to dust	0.700	0.300	0.000
I37.1 Pulmonary valve insufficiency	0.700	0.300	0.000
Z36.5 Antenatal screening for isoimmunisation	0.696	0.304	0.000
Z82.3 Family history of stroke	0.696	0.304	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.696	0.304	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.695	0.305	0.000
Z37.9 Outcome of delivery unspecified	0.694	0.306	0.000
Z37.7 Other multiple births, all stillborn	0.694	0.306	0.000
Z37.6 Other multiple births, some liveborn	0.694	0.306	0.000
Z37.5 Other multiple births, all liveborn	0.694	0.306	0.000
Z37.4 Twins, both stillborn	0.694	0.306	0.000
Z37.3 Twins, one liveborn and one stillborn	0.694	0.306	0.000
G96 Other disorders of central nervous system	0.694	0.306	0.000
I25.3 Aneurysm of heart	0.694	0.306	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.692	0.308	0.000
G92 Toxic encephalopathy	0.692	0.308	0.000
Z89.5 Acquired absence of leg at or below knee	0.692	0.308	0.000
Z89.4 Acquired absence of foot and ankle	0.690	0.310	0.000
I77.1 Stricture of artery	0.687	0.313	0.000
J86 Pyothorax	0.685	0.315	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.685	0.315	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.685	0.315	0.000
G43 Migraine	0.684	0.316	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.684	0.316	0.000
Z94.1 Heart transplant status	0.683	0.316	0.000
I78.1 Naevus, nonneoplastic	0.682	0.318	0.000
Z28 Immunisation not carried out	0.679	0.321	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.679	0.321	0.000
Z26 Need for immunisation against other single infectious diseases	0.679	0.321	0.000
Z25 Need for immunisation against other single viral diseases	0.679	0.321	0.000
Z24 Need for immunisation against certain single viral diseases	0.679	0.321	0.000
Z23 Need for immunisation against single bacterial diseases	0.679	0.321	0.000
Z20 Contact with and exposure to communicable diseases	0.679	0.321	0.000
Z94.2 Lung transplant status	0.679	0.321	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.678	0.322	0.000
I45.0 Right fascicular block	0.677	0.322	0.000
Z74.8 Other problems related to care-provider dependency	0.677	0.322	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.677	0.323	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.677	0.323	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.677	0.323	0.000
I06 Rheumatic aortic valve diseases	0.677	0.323	0.000
Z84 Family history of other conditions	0.674	0.326	0.000
I44.1 Atrioventricular block, second degree	0.674	0.326	0.000
J94.8 Other specified pleural conditions	0.673	0.327	0.000
J41 Simple and mucopurulent chronic bronchitis	0.672	0.328	0.000
J43.1 Panlobular emphysema	0.671	0.328	0.000
J43.0 MacLeod's syndrome	0.671	0.328	0.000
I35.9 Aortic valve disorder, unspecified	0.670	0.330	0.000
I20.9 Angina pectoris, unspecified	0.665	0.335	0.000
Z92 Personal history of medical treatment	0.662	0.338	0.000
I31.3 Pericardial effusion (noninflammatory)	0.662	0.338	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.661	0.339	0.000
I07.1 Tricuspid insufficiency	0.660	0.340	0.000
G41 Status epilepticus	0.659	0.341	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.658	0.342	0.000
I70 Atherosclerosis	0.658	0.342	0.000
G93 Other disorders of brain	0.656	0.344	0.000
Z57.3 Occupational exposure to other air contaminants	0.656	0.344	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.656	0.344	0.000
Z74.3 Need for continuous supervision	0.655	0.345	0.000
I46.1 Sudden cardiac death, so described	0.654	0.346	0.000
Z89.9 Acquired absence of limb, unspecified	0.652	0.348	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.652	0.348	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.652	0.348	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.652	0.348	0.000
Z89.1 Acquired absence of hand and wrist	0.652	0.348	0.000
J09-J18 Influenza and pneumonia	0.651	0.349	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.650	0.349	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.650	0.349	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.650	0.350	0.000
I51.4 Myocarditis, unspecified	0.650	0.350	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.648	0.352	0.000
Z94.6 Bone transplant status	0.648	0.352	0.000
Z94.5 Skin transplant status	0.648	0.352	0.000
Z94.3 Heart and lungs transplant status	0.648	0.352	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.645	0.355	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.645	0.355	0.000
Q50-Q56 Congenital malformations of genital organs	0.642	0.358	0.000
Z59 Problems related to housing and economic circumstances	0.642	0.358	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.641	0.359	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.640	0.360	0.000
Z71.9 Counselling, unspecified	0.639	0.360	0.000
Z65 Problems related to other psychosocial circumstances	0.639	0.361	0.000
Z62 Other problems related to upbringing	0.639	0.361	0.000
Z61 Problems related to negative life events in childhood	0.639	0.361	0.000
Z55 Problems related to education and literacy	0.639	0.361	0.000
G94.1 Hydrocephalus in neoplastic disease	0.636	0.364	0.000
G90.2 Horner's syndrome	0.636	0.364	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.636	0.364	0.000
I35.1 Aortic (valve) insufficiency	0.634	0.366	0.000
J96 Respiratory failure, not elsewhere classified	0.634	0.366	0.000
Z99.2 Dependence on renal dialysis	0.634	0.366	0.000
I24.1 Dressler's syndrome	0.633	0.366	0.000
J95.0 Tracheostomy malfunction	0.633	0.367	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.632	0.367	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.632	0.367	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.632	0.367	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.632	0.367	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.632	0.368	0.000
J42 Unspecified chronic bronchitis	0.632	0.368	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.631	0.368	0.000
Z99.4 Dependence on artificial heart	0.631	0.368	0.000
Z99.0 Dependence on aspirator	0.631	0.368	0.000
J94.1 Fibrothorax	0.630	0.370	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.630	0.370	0.000
Z74.1 Need for assistance with personal care	0.629	0.371	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.628	0.372	0.000
I74.5 Embolism and thrombosis of iliac artery	0.626	0.374	0.000
J94.2 Haemothorax	0.625	0.375	0.000
I78.8 Other diseases of capillaries	0.624	0.375	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.623	0.377	0.000
Z75.8 Other problems related to medical facilities and other health care	0.622	0.378	0.000
Z63.4 Disappearance and death of family member	0.621	0.379	0.000
Z56 Problems related to employment and unemployment	0.620	0.379	0.000
J95.9 Postprocedural respiratory disorder, unspecified	0.620	0.380	0.000
J95.5 Postprocedural subglottic stenosis	0.620	0.380	0.000
J95.4 Mendelson's syndrome	0.620	0.380	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.620	0.380	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.620	0.380	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.620	0.380	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.620	0.380	0.000
Z22.9 Carrier of infectious disease, unspecified	0.620	0.380	0.000
Z22.8 Carrier of other infectious diseases	0.620	0.380	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.620	0.380	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.620	0.380	0.000
Z22.2 Carrier of diphtheria	0.620	0.380	0.000
Z22.0 Carrier of typhoid	0.620	0.380	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.619	0.381	0.000
Z81 Family history of mental and behavioural disorders	0.618	0.382	0.000
Z99.3 Dependence on wheelchair	0.618	0.382	0.000
Z63.5 Disruption of family by separation and divorce	0.617	0.383	0.000
Z34.8 Supervision of other normal pregnancy	0.617	0.383	0.000
Z39.1 Care and examination of lactating mother	0.615	0.385	0.000
Z22.5 Carrier of viral hepatitis	0.615	0.385	0.000
G91 Hydrocephalus	0.614	0.386	0.000
Z29.9 Prophylactic measure, unspecified	0.613	0.387	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.610	0.390	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.610	0.390	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.607	0.393	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.607	0.393	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.606	0.393	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.606	0.394	0.000
I44.5 Left posterior fascicular block	0.606	0.394	0.000
I44.4 Left anterior fascicular block	0.606	0.394	0.000
Z71.2 Person consulting for explanation of investigation findings	0.605	0.394	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.606	0.394	0.000
I44.3 Other and unspecified atrioventricular block	0.605	0.395	0.000
Z64 Problems related to certain psychosocial circumstances	0.605	0.395	0.000
J60-J70 Lung diseases due to external agents	0.605	0.395	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.604	0.396	0.000
I25.4 Coronary artery aneurysm	0.602	0.397	0.000
Z76.3 Healthy person accompanying sick person	0.600	0.400	0.000
J85 Abscess of lung and mediastinum	0.599	0.401	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.599	0.401	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.599	0.401	0.000
I31.1 Chronic constrictive pericarditis	0.598	0.402	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.597	0.403	0.000
J00 Acute nasopharyngitis [common cold]	0.594	0.406	0.000
Q80-Q89 Other congenital malformations	0.592	0.408	0.000
Z72 Problems related to lifestyle	0.592	0.408	0.000
Z63.0 Problems in relationship with spouse or partner	0.592	0.408	0.000
I37.9 Pulmonary valve disorder, unspecified	0.591	0.408	0.000
I37.8 Other pulmonary valve disorders	0.591	0.408	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.591	0.408	0.000
I37.0 Pulmonary valve stenosis	0.591	0.408	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.591	0.409	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.590	0.410	0.000
Z38.0 Singleton, born in hospital	0.590	0.410	0.000
I06.0 Rheumatic aortic stenosis	0.590	0.410	0.000
G43.9 Migraine, unspecified	0.589	0.411	0.000
J94.9 Pleural condition, unspecified	0.588	0.411	0.000
J94.0 Chylous effusion	0.588	0.411	0.000
J18 Pneumonia, organism unspecified	0.588	0.412	0.000
Z58.1 Exposure to air pollution	0.587	0.413	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.586	0.414	0.000
G93.6 Cerebral oedema	0.586	0.414	0.000
Z75.2 Other waiting period for investigation and treatment	0.583	0.416	0.000
G00 Bacterial meningitis, not elsewhere classified	0.583	0.417	0.000
I35.8 Other aortic valve disorders	0.583	0.417	0.000
Z94.0 Kidney transplant status	0.582	0.418	0.000
I78.9 Disease of capillaries, unspecified	0.582	0.418	0.000
Z35.5 Supervision of elderly primigravida	0.580	0.420	0.000
G44 Other headache syndromes	0.580	0.420	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.579	0.421	0.000
G30-G32 Other degenerative diseases of the nervous system	0.578	0.422	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.578	0.422	0.000
Z57.8 Occupational exposure to other risk-factors	0.578	0.422	0.000
Z57.7 Occupational exposure to vibration	0.578	0.422	0.000
Z57.6 Occupational exposure to extreme temperature	0.578	0.422	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.578	0.422	0.000
Z57.1 Occupational exposure to radiation	0.578	0.422	0.000
Z57.0 Occupational exposure to noise	0.578	0.422	0.000
G93.9 Disorder of brain, unspecified	0.577	0.423	0.000
Z31.2 In vitro fertilisation	0.576	0.424	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.576	0.424	0.000
I45.3 Trifascicular block	0.575	0.425	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.574	0.426	0.000
J18.1 Lobar pneumonia, unspecified	0.573	0.427	0.000
I77.0 Arteriovenous fistula, acquired	0.573	0.427	0.000
Z29.1 Prophylactic immunotherapy	0.572	0.427	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.572	0.427	0.000
I09 Other rheumatic heart diseases	0.572	0.428	0.000
J40 Bronchitis, not specified as acute or chronic	0.572	0.428	0.000
J86.9 Pyothorax without fistula	0.569	0.431	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.569	0.431	0.000
Z83.5 Family history of eye and ear disorders	0.568	0.432	0.000
G45.3 Amaurosis fugax	0.567	0.433	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.566	0.434	0.000
G20-G26 Extrapyramidal and movement disorders	0.562	0.437	0.001
G90.8 Other disorders of autonomic nervous system	0.562	0.438	0.000
G90.4 Autonomic dysreflexia	0.562	0.438	0.000
G90.3 Multisystem degeneration	0.562	0.438	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.562	0.438	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.562	0.438	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.562	0.438	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.562	0.438	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.562	0.438	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.562	0.438	0.000
Q35-Q37 Cleft lip and cleft palate	0.562	0.438	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.562	0.438	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.559	0.441	0.000
G71 Primary disorders of muscles	0.558	0.442	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.557	0.443	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.557	0.443	0.000
Z35.6 Supervision of very young primigravida	0.557	0.443	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.557	0.443	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.557	0.443	0.000
I33.0 Acute and subacute infective endocarditis	0.557	0.443	0.000
I30.9 Acute pericarditis, unspecified	0.556	0.444	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.554	0.445	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.554	0.445	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.554	0.445	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.553	0.447	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.553	0.447	0.000
Z75.0 Medical services not available in home	0.553	0.447	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.553	0.447	0.000
I31.8 Other specified diseases of pericardium	0.552	0.448	0.000
I31.2 Haemopericardium, not elsewhere classified	0.552	0.448	0.000
I31.0 Chronic adhesive pericarditis	0.552	0.448	0.000
Z31.9 Procreative management, unspecified	0.551	0.448	0.000
Z31.8 Other procreative management	0.551	0.448	0.000
Z31.6 General counselling and advice on procreation	0.551	0.448	0.000
Z31.5 Genetic counselling	0.551	0.448	0.000
Z31.3 Other assisted fertilisation methods	0.551	0.448	0.000
Z31.1 Artifical insemination	0.551	0.448	0.000
O85-O92 Complications predominantly related to the puerperium	0.551	0.449	0.000
G83 Other paralytic syndromes	0.550	0.450	0.000
J04 Acute laryngitis and tracheitis	0.549	0.451	0.000
Q23 Congenital malformations of aortic and mitral valves	0.548	0.452	0.000
I73 Other peripheral vascular diseases	0.548	0.452	0.000
Q51 Congenital malformations of uterus and cervix	0.546	0.454	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.545	0.455	0.000
Z38.8 Other multiple, unspecified as to place of birth	0.544	0.456	0.000
Z38.7 Other multiple, born outside hospital	0.544	0.456	0.000
Z38.6 Other multiple, born in hospital	0.544	0.456	0.000
Z38.5 Twin, unspecified as to place of birth	0.544	0.456	0.000
Z38.4 Twin, born outside hospital	0.544	0.456	0.000
Z38.3 Twin, born in hospital	0.544	0.456	0.000
Z38.2 Singleton, unspecified as to place of birth	0.544	0.456	0.000
Z38.1 Singleton, born outside hospital	0.544	0.456	0.000
Z76.8 Persons encountering health services in other specified circumstances	0.543	0.457	0.000
Z76.5 Malingerer [conscious situation]	0.543	0.457	0.000
Z76.4 Other boarder in health-care facility	0.543	0.457	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.543	0.457	0.000
Z76.1 Health supervision and care of foundling	0.543	0.457	0.000
Z76.0 Issue of repeat prescription	0.543	0.457	0.000
G35 Multiple sclerosis	0.542	0.458	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.541	0.459	0.000
Z63.9 Problem related to primary support group, unspecified	0.541	0.459	0.000
Z63.6 Dependent relative needing care at home	0.541	0.459	0.000
Z63.3 Absence of family member	0.541	0.459	0.000
Z63.2 Inadequate family support	0.541	0.459	0.000
Z63.1 Problems in relationship with parents and in-laws	0.541	0.459	0.000
Z39.2 Routine postpartum follow-up	0.540	0.459	0.000
G43.8 Other migraine	0.539	0.461	0.000
Z32 Pregnancy examination and test	0.538	0.462	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.538	0.462	0.000
J86.0 Pyothorax with fistula	0.537	0.463	0.000
Z94.8 Other transplanted organ and tissue status	0.536	0.464	0.000
I21.4 Acute subendocardial myocardial infarction	0.536	0.464	0.000
Z73.6 Limitation of activities due to disability	0.534	0.466	0.000
Z73.5 Social role conflict, not elsewhere classified	0.534	0.466	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.534	0.466	0.000
Z73.2 Lack of relaxation and leisure	0.534	0.466	0.000
Z73.1 Accentuation of personality traits	0.534	0.466	0.000
Z73.0 Burn-out	0.534	0.466	0.000
Z34.0 Supervision of normal first pregnancy	0.533	0.467	0.000
I77.5 Necrosis of artery	0.533	0.467	0.000
I77.4 Coeliac artery compression syndrome	0.533	0.467	0.000
I77.3 Arterial fibromuscular dysplasia	0.533	0.467	0.000
I77.2 Rupture of artery	0.533	0.467	0.000
I33.9 Acute endocarditis, unspecified	0.532	0.468	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.532	0.468	0.000
I30.8 Other forms of acute pericarditis	0.531	0.469	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.531	0.469	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.529	0.470	0.000
J01 Acute sinusitis	0.529	0.471	0.000
I30.1 Infective pericarditis	0.529	0.471	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.528	0.472	0.000
G41.0 Grand mal status epilepticus	0.528	0.472	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.523	0.477	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.523	0.477	0.000
I74.8 Embolism and thrombosis of other arteries	0.523	0.477	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.523	0.477	0.000
G82 Paraplegia and tetraplegia	0.522	0.478	0.000
I70.1 Atherosclerosis of renal artery	0.521	0.479	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.521	0.479	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations