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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11045000
log Bayes Factor = 7.56762
Chromosome 12   position 20,184,146  (GRCh37) Explore rs11045000 on Ensembl!
Variant rs11045000 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.002 0.998
I10 Essential (primary) hypertension
0.000 0.002 0.998
I25.2 Old myocardial infarction
0.000 0.015 0.985
I20 Angina pectoris
0.000 0.016 0.984
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.039 0.961
I10-I15 Hypertensive diseases
0.000 0.040 0.960
Chapter IX Diseases of the circulatory system
0.000 0.055 0.945
I20.8 Other forms of angina pectoris
0.000 0.071 0.929
I20.9 Angina pectoris, unspecified
0.000 0.089 0.911
I65.2 Occlusion and stenosis of carotid artery
0.000 0.132 0.868
I60-I69 Cerebrovascular diseases
0.000 0.133 0.867
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.134 0.866
I21 Acute myocardial infarction
0.000 0.136 0.864
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.151 0.849
I25.5 Ischaemic cardiomyopathy
0.000 0.183 0.817
I60 Subarachnoid haemorrhage
0.000 0.190 0.810
I21.9 Acute myocardial infarction, unspecified
0.000 0.193 0.807
I25.4 Coronary artery aneurysm
0.000 0.205 0.795
I25.3 Aneurysm of heart
0.000 0.206 0.794
I20.1 Angina pectoris with documented spasm
0.000 0.243 0.757
I23 Certain current complications following acute myocardial infarction
0.000 0.243 0.757
I20.0 Unstable angina
0.000 0.255 0.745
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.256 0.744
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.263 0.737
I22 Subsequent myocardial infarction
0.000 0.265 0.735
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I12 Hypertensive renal disease
0.000 0.300 0.700
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.300 0.699
I60.8 Other subarachnoid haemorrhage
0.000 0.311 0.689
I13 Hypertensive heart and renal disease
0.000 0.312 0.688
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.318 0.682
I00-I02 Acute rheumatic fever
0.000 0.322 0.677
I24 Other acute ischaemic heart diseases
0.000 0.336 0.664
I15 Secondary hypertension
0.000 0.352 0.648
I12.9 Hypertensive renal disease without renal failure
0.000 0.363 0.637
I71 Aortic aneurysm and dissection
0.000 0.370 0.630
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.378 0.622
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.378 0.622
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.379 0.621
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.379 0.621
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.379 0.621
I65.1 Occlusion and stenosis of basilar artery
0.000 0.379 0.621
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.380 0.620
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.385 0.615
I74 Arterial embolism and thrombosis
0.000 0.388 0.612
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.392 0.608
I63 Cerebral infarction
0.000 0.398 0.602
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.405 0.595
I78 Diseases of capillaries
0.000 0.415 0.585
I23.8 Other current complications following acute myocardial infarction
0.000 0.417 0.583
I22.8 Subsequent myocardial infarction of other sites
0.000 0.419 0.581
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.419 0.581
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.419 0.581
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.419 0.581
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.425 0.575
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.428 0.572
I63.8 Other cerebral infarction
0.000 0.428 0.572
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.430 0.570
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.437 0.563
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.443 0.557
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.448 0.552
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.457 0.542
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.457 0.542
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.457 0.542
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.457 0.542
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.457 0.542
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.457 0.542
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.457 0.542
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.461 0.539
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.467 0.533
I11 Hypertensive heart disease
0.000 0.472 0.528
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.474 0.526
E78.0 Pure hypercholesterolaemia
0.000 0.475 0.525
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.478 0.522
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.487 0.513
I78.1 Naevus, nonneoplastic
0.000 0.487 0.513
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.501 0.499
I21.4 Acute subendocardial myocardial infarction
0.000 0.503 0.497
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.506 0.494
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.506 0.494
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.506 0.494
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.506 0.494
I02 Rheumatic chorea
0.000 0.514 0.486
I01 Rheumatic fever with heart involvement
0.000 0.514 0.486
I00 Rheumatic fever without mention of heart involvement
0.000 0.514 0.486
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.520 0.480
I24.8 Other forms of acute ischaemic heart disease
0.000 0.521 0.479
I24.1 Dressler's syndrome
0.000 0.523 0.476
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.524 0.476
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.529 0.471
I15.8 Other secondary hypertension
0.000 0.535 0.465
I15.2 Hypertension secondary to endocrine disorders
0.000 0.535 0.465
I15.0 Renovascular hypertension
0.000 0.535 0.465
I15.1 Hypertension secondary to other renal disorders
0.000 0.543 0.456
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.548 0.451
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.548 0.451
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.548 0.451
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.548 0.451
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.555 0.445
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.561 0.439
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.561 0.439
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.561 0.439
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.564 0.436
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.564 0.436
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.564 0.436
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.564 0.436
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.564 0.436
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.564 0.436
I15.9 Seconday hypertension, unspecified
0.000 0.565 0.435
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.568 0.432
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.568 0.432
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.568 0.432
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.569 0.431
I74.5 Embolism and thrombosis of iliac artery
0.000 0.571 0.429
I78.8 Other diseases of capillaries
0.000 0.573 0.427
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.577 0.422
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.579 0.421
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.579 0.421
I78.9 Disease of capillaries, unspecified
0.000 0.581 0.419
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.584 0.415
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.586 0.414
I74.8 Embolism and thrombosis of other arteries
0.000 0.587 0.413
I71.0 Dissection of aorta [any part]
0.000 0.591 0.409
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.596 0.404
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.596 0.404
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.596 0.404
I62 Other nontraumatic intracranial haemorrhage
0.000 0.601 0.398
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.611 0.389
E78.5 Hyperlipidaemia, unspecified
0.000 0.614 0.386
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.619 0.380
E78.4 Other hyperlipidaemia
0.000 0.622 0.378
I70 Atherosclerosis
0.000 0.643 0.357
I77 Other disorders of arteries and arterioles
0.000 0.649 0.351
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.651 0.348
I01.8 Other acute rheumatic heart disease
0.000 0.651 0.348
I01.2 Acute rheumatic myocarditis
0.000 0.651 0.348
I01.1 Acute rheumatic endocarditis
0.000 0.651 0.348
I01.0 Acute rheumatic pericarditis
0.000 0.651 0.348
I02.9 Rheumatic chorea without heart involvement
0.000 0.651 0.348
I02.0 Rheumatic chorea with heart involvement
0.000 0.651 0.348
I68.0 Cerebral amyloid angiopathy
0.000 0.655 0.345
E78.1 Pure hyperglyceridaemia
0.000 0.678 0.322
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.691 0.309
I79.1 Aortitis in diseases classified elsewhere
0.000 0.691 0.309
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.691 0.309
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.697 0.303
E78.6 Lipoprotein deficiency
0.000 0.698 0.302
E78.3 Hyperchylomicronaemia
0.000 0.698 0.302
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.703 0.297
I62.1 Nontraumatic extradural haemorrhage
0.000 0.714 0.286
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.716 0.283
I72 Other aneurysm
0.000 0.722 0.277
I69 Sequelae of cerebrovascular disease
0.000 0.731 0.269
E78.2 Mixed hyperlipidaemia
0.000 0.740 0.260
I70.9 Generalised and unspecified atherosclerosis
0.000 0.744 0.256
I77.8 Other specified disorders of arteries and arterioles
0.000 0.745 0.255
I77.5 Necrosis of artery
0.000 0.748 0.252
I77.4 Coeliac artery compression syndrome
0.000 0.748 0.252
I77.3 Arterial fibromuscular dysplasia
0.000 0.748 0.252
I77.2 Rupture of artery
0.000 0.748 0.252
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.749 0.251
I77.0 Arteriovenous fistula, acquired
0.000 0.751 0.249
I77.6 Arteritis, unspecified
0.000 0.752 0.248
I70.0 Atherosclerosis of aorta
0.000 0.753 0.247
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.754 0.245
I70.1 Atherosclerosis of renal artery
0.000 0.756 0.244
E78.8 Other disorders of lipoprotein metabolism
0.000 0.757 0.243
I70.8 Atherosclerosis of other arteries
0.000 0.761 0.239
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.001 0.765 0.234
I71.3 Abdominal aortic aneurysm, ruptured
0.001 0.771 0.228
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.776 0.224
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.784 0.215
I28 Other diseases of pulmonary vessels
0.001 0.787 0.213
I05-I09 Chronic rheumatic heart diseases
0.000 0.787 0.212
I73 Other peripheral vascular diseases
0.000 0.793 0.207
I72.9 Aneurysm of unspecified site
0.000 0.801 0.199
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.801 0.199
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.801 0.199
I72.1 Aneurysm of artery of upper extremity
0.000 0.801 0.199
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.805 0.195
I61 Intracerebral haemorrhage
0.000 0.805 0.194
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.806 0.194
I72.4 Aneurysm of artery of lower extremity
0.000 0.806 0.193
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.807 0.193
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.816 0.184
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.816 0.184
I72.3 Aneurysm of iliac artery
0.000 0.820 0.180
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.822 0.178
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.823 0.177
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.825 0.175
I69.3 Sequelae of cerebral infarction
0.000 0.827 0.173
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.827 0.173
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.828 0.171
I77.1 Stricture of artery
0.000 0.828 0.171
I72.2 Aneurysm of renal artery
0.000 0.829 0.171
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.829 0.171
I72.0 Aneurysm of carotid artery
0.000 0.829 0.170
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.832 0.168
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.837 0.163
I72.8 Aneurysm of other specified arteries
0.000 0.840 0.159
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.846 0.154
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.847 0.153
I28.8 Other specified diseases of pulmonary vessels
0.000 0.847 0.153
I28.1 Aneurysm of pulmonary artery
0.000 0.847 0.153
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.847 0.153
I09 Other rheumatic heart diseases
0.000 0.847 0.152
I73.8 Other specified peripheral vascular diseases
0.000 0.848 0.152
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.001 0.849 0.150
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.851 0.149
I22.9 Subsequent myocardial infarction of unspecified site
0.001 0.855 0.144
I61.8 Other intracerebral haemorrhage
0.000 0.857 0.142
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.860 0.140
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.860 0.139
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.869 0.130
I06 Rheumatic aortic valve diseases
0.000 0.875 0.125
I61.3 Intracerebral haemorrhage in brain stem
0.001 0.878 0.121
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.879 0.120
I07 Rheumatic tricuspid valve diseases
0.000 0.881 0.119
I49.9 Cardiac arrhythmia, unspecified
0.000 0.882 0.118
I49 Other cardiac arrhythmias
0.000 0.883 0.117
I30-I52 Other forms of heart disease
0.000 0.883 0.117
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.001 0.884 0.115
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.885 0.115
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.885 0.115
I12.0 Hypertensive renal disease with renal failure
0.000 0.886 0.114
I67 Other cerebrovascular diseases
0.000 0.889 0.111
I09.8 Other specified rheumatic heart diseases
0.000 0.890 0.109
I09.2 Chronic rheumatic pericarditis
0.000 0.890 0.109
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.890 0.109
I09.0 Rheumatic myocarditis
0.000 0.890 0.109
I09.9 Rheumatic heart disease, unspecified
0.000 0.890 0.109
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.893 0.107
I63.9 Cerebral infarction, unspecified
0.000 0.893 0.107
I61.5 Intracerebral haemorrhage, intraventricular
0.001 0.893 0.106
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.896 0.104
I49.8 Other specified cardiac arrhythmias
0.000 0.899 0.101
I27 Other pulmonary heart diseases
0.000 0.899 0.101
I30 Acute pericarditis
0.000 0.900 0.100
I05 Rheumatic mitral valve diseases
0.000 0.901 0.099
I26 Pulmonary embolism
0.001 0.901 0.097
I44 Atrioventricular and left bundle-branch block
0.000 0.904 0.096
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.001 0.906 0.094
I42 Cardiomyopathy
0.000 0.908 0.092
I49.3 Ventricular premature depolarisation
0.000 0.908 0.092
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.910 0.090
I06.8 Other rheumatic aortic valve diseases
0.000 0.910 0.090
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.910 0.090
I08 Multiple valve diseases
0.000 0.910 0.090
I49.4 Other and unspecified premature depolarisation
0.000 0.910 0.090
I44.6 Other and unspecified fascicular block
0.000 0.911 0.089
I30.9 Acute pericarditis, unspecified
0.000 0.912 0.088
I37 Pulmonary valve disorders
0.000 0.913 0.087
I07.9 Tricuspid valve disease, unspecified
0.000 0.914 0.085
I07.8 Other tricuspid valve diseases
0.000 0.914 0.085
I07.2 Tricuspid stenosis with insufficiency
0.000 0.914 0.085
I07.0 Tricuspid stenosis
0.000 0.914 0.085
I36 Nonrheumatic tricuspid valve disorders
0.000 0.915 0.085
I49.2 Junctional premature depolarisation
0.000 0.916 0.084
I52 Other heart disorders in diseases classified elsewhere
0.000 0.916 0.084
I48 Atrial fibrillation and flutter
0.000 0.916 0.084
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.916 0.084
I41 Myocarditis in diseases classified elsewhere
0.000 0.916 0.084
I40 Acute myocarditis
0.000 0.916 0.084
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.916 0.084
I32 Pericarditis in diseases classified elsewhere
0.000 0.916 0.084
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.917 0.083
I97.0 Postcardiotomy syndrome
0.000 0.917 0.083
I97.1 Other functional disturbances following cardiac surgery
0.000 0.918 0.082
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.918 0.081
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.920 0.080
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.920 0.080
I67.5 Moyamoya disease
0.000 0.920 0.080
I67.4 Hypertensive encephalopathy
0.000 0.920 0.080
I67.3 Progressive vascular leukoencephalopathy
0.000 0.920 0.080
I06.0 Rheumatic aortic stenosis
0.001 0.921 0.078
I06.1 Rheumatic aortic insufficiency
0.001 0.922 0.078
I42.8 Other cardiomyopathies
0.000 0.922 0.078
I49.1 Atrial premature depolarisation
0.000 0.922 0.078
I51 Complications and ill-defined descriptions of heart disease
0.000 0.922 0.078
I42.2 Other hypertrophic cardiomyopathy
0.000 0.922 0.078
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.922 0.077
I44.3 Other and unspecified atrioventricular block
0.000 0.924 0.076
I33 Acute and subacute endocarditis
0.000 0.924 0.076
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.925 0.075
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.925 0.075
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.925 0.075
I98.0 Cardiovascular syphilis
0.000 0.925 0.075
I27.1 Kyphoscoliotic heart disease
0.000 0.927 0.072
I30.1 Infective pericarditis
0.000 0.928 0.072
I30.8 Other forms of acute pericarditis
0.000 0.928 0.072
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.928 0.072
I05.8 Other mitral valve diseases
0.000 0.929 0.071
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.930 0.070
I05.2 Mitral stenosis with insufficiency
0.000 0.930 0.070
I49.0 Ventricular fibrillation and flutter
0.000 0.931 0.069
I44.5 Left posterior fascicular block
0.000 0.931 0.069
I44.4 Left anterior fascicular block
0.000 0.931 0.069
I44.1 Atrioventricular block, second degree
0.000 0.931 0.068
I05.9 Mitral valve disease, unspecified
0.000 0.932 0.068
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.932 0.068
I45 Other conduction disorders
0.000 0.932 0.068
I44.2 Atrioventricular block, complete
0.000 0.933 0.067
I49.5 Sick sinus syndrome
0.000 0.934 0.066
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.934 0.066
I42.6 Alcoholic cardiomyopathy
0.000 0.934 0.066
I42.5 Other restrictive cardiomyopathy
0.000 0.934 0.066
I42.4 Endocardial fibroelastosis
0.000 0.934 0.066
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.934 0.066
I05.0 Mitral stenosis
0.000 0.934 0.066
I73.9 Peripheral vascular disease, unspecified
0.000 0.934 0.066
I37.1 Pulmonary valve insufficiency
0.000 0.934 0.066
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.935 0.065
I27.8 Other specified pulmonary heart diseases
0.000 0.935 0.065
I08.9 Multiple valve disease, unspecified
0.000 0.935 0.065
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.935 0.065
I99 Other and unspecified disorders of circulatory system
0.001 0.936 0.064
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.936 0.064
I27.9 Pulmonary heart disease, unspecified
0.000 0.936 0.064
I08.8 Other multiple valve diseases
0.000 0.936 0.064
I67.9 Cerebrovascular disease, unspecified
0.000 0.936 0.064
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.936 0.064
I37.9 Pulmonary valve disorder, unspecified
0.000 0.937 0.063
I37.8 Other pulmonary valve disorders
0.000 0.937 0.063
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.937 0.063
I37.0 Pulmonary valve stenosis
0.000 0.937 0.063
I67.1 Cerebral aneurysm, nonruptured
0.000 0.938 0.062
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.938 0.062
I51.4 Myocarditis, unspecified
0.000 0.939 0.061
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.939 0.061
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.939 0.061
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.939 0.061
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.939 0.061
I51.8 Other ill-defined heart diseases
0.000 0.939 0.061
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.940 0.060
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.940 0.060
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.940 0.060
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.940 0.060
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.940 0.060
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.940 0.060
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.940 0.060
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.940 0.060
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.940 0.060
I40.9 Acute myocarditis, unspecified
0.000 0.940 0.060
I40.8 Other acute myocarditis
0.000 0.940 0.060
I40.1 Isolated myocarditis
0.000 0.940 0.060
I40.0 Infective myocarditis
0.000 0.940 0.060
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.940 0.060
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.940 0.060
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.940 0.060
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.940 0.060
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.940 0.060
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.940 0.060
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.940 0.060
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.940 0.060
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.940 0.060
I48.4 Atypical atrial flutter
0.000 0.940 0.060
I48.3 Typical atrial flutter
0.000 0.940 0.060
I48.2 Chronic atrial fibrillation
0.000 0.940 0.060
I48.1 Persistent atrial fibrillation
0.000 0.940 0.060
I48.0 Paroxysmal atrial fibrillation
0.000 0.940 0.060
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.940 0.060
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.940 0.060
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.940 0.060
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.941 0.059
I45.8 Other specified conduction disorders
0.000 0.941 0.059
I73.0 Raynaud's syndrome
0.000 0.942 0.058
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.942 0.057
I67.2 Cerebral atherosclerosis
0.000 0.942 0.057
I27.0 Primary pulmonary hypertension
0.000 0.943 0.057
I38 Endocarditis, valve unspecified
0.000 0.943 0.057
I51.7 Cardiomegaly
0.000 0.943 0.057
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.944 0.056
I44.0 Atrioventricular block, first degree
0.000 0.944 0.056
I45.4 Nonspecific intraventricular block
0.000 0.945 0.055
I33.9 Acute endocarditis, unspecified
0.000 0.945 0.054
I51.0 Cardiac septal defect, acquired
0.000 0.947 0.053
I07.1 Tricuspid insufficiency
0.000 0.948 0.052
I42.0 Dilated cardiomyopathy
0.000 0.948 0.052
I45.3 Trifascicular block
0.000 0.950 0.050
I46 Cardiac arrest
0.000 0.951 0.049
I45.2 Bifascicular block
0.000 0.951 0.049
I45.0 Right fascicular block
0.000 0.951 0.049
I51.5 Myocardial degeneration
0.000 0.951 0.048
I51.9 Heart disease, unspecified
0.000 0.952 0.048
I45.1 Other and unspecified right bundle-branch block
0.000 0.953 0.047
I47 Paroxysmal tachycardia
0.000 0.953 0.047
I33.0 Acute and subacute infective endocarditis
0.000 0.953 0.046
I44.7 Left bundle-branch block, unspecified
0.000 0.953 0.046
I42.9 Cardiomyopathy, unspecified
0.000 0.954 0.046
I27.2 Other secondary pulmonary hypertension
0.000 0.954 0.045
I51.6 Cardiovascular disease, unspecified
0.000 0.956 0.044
I45.5 Other specified heart block
0.000 0.957 0.043
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.958 0.042
I05.1 Rheumatic mitral insufficiency
0.001 0.959 0.040
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.959 0.040
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.959 0.041
I89.1 Lymphangitis
0.000 0.960 0.040
O70.0 First degree perineal laceration during delivery
0.000 0.963 0.037
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.963 0.037
I46.1 Sudden cardiac death, so described
0.000 0.964 0.035
I31 Other diseases of pericardium
0.001 0.966 0.033
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.967 0.033
I47.0 Reentry ventricular arrhythmia
0.000 0.968 0.032
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.969 0.031
I45.6 Preexcitation syndrome
0.000 0.969 0.030
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.970 0.030
I47.2 Ventricular tachycardia
0.000 0.970 0.030
I46.9 Cardiac arrest, unspecified
0.000 0.970 0.030
I88 Nonspecific lymphadenitis
0.000 0.972 0.028
I81 Portal vein thrombosis
0.000 0.974 0.026
I89.0 Lymphoedema, not elsewhere classified
0.000 0.974 0.026
I83 Varicose veins of lower extremities
0.000 0.974 0.026
I31.8 Other specified diseases of pericardium
0.001 0.976 0.024
I31.2 Haemopericardium, not elsewhere classified
0.001 0.976 0.024
I31.1 Chronic constrictive pericarditis
0.001 0.976 0.024
I31.0 Chronic adhesive pericarditis
0.001 0.976 0.024
I45.9 Conduction disorder, unspecified
0.000 0.976 0.023
M54.99 Dorsalgia, unspecified (Site unspecified)
0.024 0.976 0.000
I67.8 Other specified cerebrovascular diseases
0.000 0.978 0.022
I34 Nonrheumatic mitral valve disorders
0.000 0.978 0.022
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.978 0.022
I85 Oesophageal varices
0.000 0.980 0.020
I88.8 Other nonspecific lymphadenitis
0.000 0.980 0.020
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.980 0.020
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.980 0.020
I08.0 Disorders of both mitral and aortic valves
0.000 0.980 0.019
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.981 0.019
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.981 0.019
I87 Other disorders of veins
0.000 0.981 0.019
I86 Varicose veins of other sites
0.000 0.982 0.018
I80 Phlebitis and thrombophlebitis
0.000 0.982 0.018
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.983 0.017
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.983 0.017
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.984 0.016
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.984 0.016
I95 Hypotension
0.000 0.985 0.015
I46.0 Cardiac arrest with successful resuscitation
0.000 0.985 0.015
I50 Heart failure
0.000 0.985 0.015
I31.9 Disease of pericardium, unspecified
0.000 0.985 0.014
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.986 0.014
M54.9 Dorsalgia, unspecified
0.014 0.986 0.000
I87.9 Disorder of vein, unspecified
0.000 0.986 0.014
I87.0 Postphlebitic syndrome
0.000 0.986 0.014
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.986 0.013
I82 Other venous embolism and thrombosis
0.000 0.987 0.013
I86.8 Varicose veins of other specified sites
0.000 0.987 0.013
I86.3 Vulval varices
0.000 0.987 0.013
I86.0 Sublingual varices
0.000 0.987 0.013
I87.1 Compression of vein
0.000 0.987 0.012
M54.96 Dorsalgia, unspecified (Lumbar region)
0.013 0.987 0.000
L05.0 Pilonidal cyst with abscess
0.012 0.988 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.012 0.988 0.000
I95.0 Idiopathic hypotension
0.000 0.988 0.012
I47.1 Supraventricular tachycardia
0.000 0.988 0.012
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.988 0.012
I85.0 Oesophageal varices with bleeding
0.000 0.988 0.011
D47.1 Chronic myeloproliferative disease
0.011 0.989 0.000
I86.2 Pelvic varices
0.000 0.989 0.011
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.011 0.989 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.989 0.011
D41.0 Kidney
0.010 0.989 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.011 0.989 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.010 0.989 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.010 0.989 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.010 0.989 0.000
I86.1 Scrotal varices
0.000 0.990 0.010
I85.9 Oesophageal varices without bleeding
0.000 0.990 0.010
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.010 0.990 0.000
I82.1 Thrombophlebitis migrans
0.000 0.990 0.010
M54.94 Dorsalgia, unspecified (Thoracic region)
0.010 0.990 0.000
D41.4 Bladder
0.010 0.990 0.000
I86.4 Gastric varices
0.000 0.990 0.009
I82.3 Embolism and thrombosis of renal vein
0.000 0.990 0.009
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.010 0.990 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.009 0.990 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.991 0.009
D37-D48 Neoplasms of uncertain or unknown behaviour
0.009 0.991 0.000
I87.8 Other specified disorders of veins
0.000 0.991 0.009
D45 Polycythaemia vera
0.009 0.991 0.000
I82.2 Embolism and thrombosis of vena cava
0.000 0.991 0.009
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.009 0.991 0.000
I82.0 Budd-Chiari syndrome
0.000 0.991 0.008
L05 Pilonidal cyst
0.009 0.991 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.008 0.992 0.000
I95.8 Other hypotension
0.001 0.992 0.008
C64 Malignant neoplasm of kidney, except renal pelvis
0.008 0.992 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.008 0.992 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.992 0.008
L05.9 Pilonidal cyst without abscess
0.008 0.992 0.000
D40.1 Testis
0.008 0.992 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.008 0.992 0.000
D41.9 Urinary organ, unspecified
0.008 0.992 0.000
D41.7 Other urinary organs
0.008 0.992 0.000
D41.3 Urethra
0.008 0.992 0.000
D41.2 Ureter
0.008 0.992 0.000
D41.1 Renal pelvis
0.008 0.992 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.992 0.007
I35 Nonrheumatic aortic valve disorders
0.000 0.992 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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