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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117564322
log Bayes Factor = 46.2816
Chromosome 7   position 150,684,021  (GRCh37) Explore rs117564322 on Ensembl!
Variant rs117564322 is part of Cluster X0093

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Z50 Care involving use of rehabilitation procedures
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
1.000 0.000 0.000
I20 Angina pectoris
0.999 0.001 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.999 0.001 0.000
I21.9 Acute myocardial infarction, unspecified
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
M20 Acquired deformities of fingers and toes
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
I20.9 Angina pectoris, unspecified
0.998 0.002 0.000
M20.4 Other hammer toe(s) (acquired)
0.997 0.003 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.996 0.004 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.996 0.004 0.000
Z50.1 Other physical therapy
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
I25.2 Old myocardial infarction
0.994 0.006 0.000
G40 Epilepsy
0.991 0.009 0.000
I69 Sequelae of cerebrovascular disease
0.991 0.009 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
G40.9 Epilepsy, unspecified
0.986 0.014 0.000
I63 Cerebral infarction
0.980 0.020 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.978 0.022 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.974 0.026 0.000
E00-E07 Disorders of thyroid gland
0.973 0.027 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.971 0.029 0.000
M20.1 Hallux valgus (acquired)
0.971 0.029 0.000
I73 Other peripheral vascular diseases
0.969 0.031 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
B95-B98 Bacterial, viral and other infectious agents
0.966 0.034 0.000
I63.9 Cerebral infarction, unspecified
0.962 0.038 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.962 0.038 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.961 0.039 0.000
I51 Complications and ill-defined descriptions of heart disease
0.959 0.041 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.955 0.045 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.952 0.048 0.000
M24 Other specific joint derangements
0.949 0.051 0.000
I50 Heart failure
0.949 0.051 0.000
M25 Other joint disorders, not elsewhere classified
0.948 0.052 0.000
I20.0 Unstable angina
0.945 0.055 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.944 0.056 0.000
S00-S09 Injuries to the head
0.942 0.058 0.000
Z45 Adjustment and management of implanted device
0.941 0.059 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.938 0.062 0.000
G81 Hemiplegia
0.938 0.062 0.000
I73.9 Peripheral vascular disease, unspecified
0.937 0.063 0.000
I74 Arterial embolism and thrombosis
0.936 0.064 0.000
E04 Other non-toxic goitre
0.935 0.065 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.924 0.076 0.000
G81.9 Hemiplegia, unspecified
0.921 0.079 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.917 0.083 0.000
I24 Other acute ischaemic heart diseases
0.916 0.084 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.915 0.085 0.000
Z50.8 Care involving use of rehabilitation procedures
0.914 0.086 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.907 0.093 0.000
I44 Atrioventricular and left bundle-branch block
0.903 0.097 0.000
I21.4 Acute subendocardial myocardial infarction
0.902 0.098 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.899 0.101 0.000
Chapter V Mental and behavioural disorders
0.899 0.101 0.000
I51.8 Other ill-defined heart diseases
0.888 0.112 0.000
Z40 Prophylactic surgery
0.887 0.113 0.000
I12 Hypertensive renal disease
0.885 0.115 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.885 0.115 0.000
T92 Sequelae of injuries of upper limb
0.884 0.116 0.000
T91 Sequelae of injuries of neck and trunk
0.884 0.116 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.883 0.117 0.000
G47 Sleep disorders
0.881 0.119 0.000
I05-I09 Chronic rheumatic heart diseases
0.878 0.122 0.000
M25.4 Effusion of joint
0.877 0.123 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.876 0.124 0.000
E04.1 Non-toxic single thyroid nodule
0.876 0.124 0.000
I50.1 Left ventricular failure
0.875 0.125 0.000
I50.0 Congestive heart failure
0.875 0.125 0.000
Z49 Care involving dialysis
0.875 0.125 0.000
I72 Other aneurysm
0.871 0.129 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.868 0.132 0.000
Z50.0 Cardiac rehabilitation
0.865 0.135 0.000
B35-B49 Mycoses
0.864 0.136 0.000
M24.1 Other articular cartilage disorders
0.863 0.137 0.000
I27 Other pulmonary heart diseases
0.860 0.140 0.000
S80-S89 Injuries to the knee and lower leg
0.860 0.140 0.000
Z45.8 Adjustment and management of other implanted devices
0.857 0.143 0.000
S06 Intracranial injury
0.855 0.145 0.000
E07 Other disorders of thyroid
0.854 0.146 0.000
G43 Migraine
0.854 0.146 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.853 0.147 0.000
E04.2 Non-toxic multinodular goitre
0.850 0.150 0.000
M45-M49 Spondylopathies
0.849 0.151 0.000
I26 Pulmonary embolism
0.849 0.151 0.000
M20.2 Hallux rigidus
0.847 0.153 0.000
I33 Acute and subacute endocarditis
0.845 0.154 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.845 0.155 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.843 0.157 0.000
I63.8 Other cerebral infarction
0.843 0.157 0.000
Z50.2 Alcohol rehabilitation
0.842 0.157 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.841 0.159 0.000
T66-T78 Other and unspecified effects of external causes
0.838 0.162 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.836 0.164 0.000
Y85 Sequelae of transport accidents
0.836 0.164 0.000
I47 Paroxysmal tachycardia
0.834 0.166 0.000
E20-E35 Disorders of other endocrine glands
0.834 0.166 0.000
I70 Atherosclerosis
0.833 0.167 0.000
I23 Certain current complications following acute myocardial infarction
0.830 0.170 0.000
T90 Sequelae of injuries of head
0.824 0.176 0.000
I12.0 Hypertensive renal disease with renal failure
0.819 0.181 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.818 0.182 0.000
I49 Other cardiac arrhythmias
0.818 0.182 0.000
E50-E64 Other nutritional deficiencies
0.817 0.183 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.817 0.183 0.000
F30-F39 Mood [affective] disorders
0.816 0.184 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.814 0.186 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.813 0.187 0.000
E65-E68 Obesity and other hyperalimentation
0.812 0.188 0.000
Z52 Donors of organs and tissues
0.811 0.189 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.811 0.189 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.808 0.192 0.000
M60-M63 Disorders of muscles
0.807 0.193 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.807 0.193 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.806 0.194 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.804 0.196 0.000
Y44 Agents primarily affecting blood constituents
0.803 0.197 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.803 0.197 0.000
I73.0 Raynaud's syndrome
0.803 0.197 0.000
I51.7 Cardiomegaly
0.803 0.197 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.802 0.198 0.000
S20-S29 Injuries to the thorax
0.800 0.200 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.800 0.200 0.000
E06 Thyroiditis
0.799 0.200 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.798 0.202 0.000
I61 Intracerebral haemorrhage
0.798 0.202 0.000
I24.8 Other forms of acute ischaemic heart disease
0.797 0.203 0.000
G47.3 Sleep apnoea
0.796 0.204 0.000
G90-G99 Other disorders of the nervous system
0.795 0.205 0.000
I47.2 Ventricular tachycardia
0.795 0.205 0.000
A00-A09 Intestinal infectious diseases
0.795 0.205 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.794 0.206 0.000
Z30 Contraceptive management
0.793 0.207 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.793 0.207 0.000
I20.8 Other forms of angina pectoris
0.791 0.209 0.000
M21 Other acquired deformities of limbs
0.788 0.212 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.787 0.212 0.000
I25.5 Ischaemic cardiomyopathy
0.787 0.213 0.000
I37 Pulmonary valve disorders
0.787 0.213 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.786 0.214 0.000
Y86 Sequelae of other accidents
0.784 0.216 0.000
Z49.1 Extracorporeal dialysis
0.782 0.218 0.000
M45 Ankylosing spondylitis
0.781 0.219 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
M91-M94 Chondropathies
0.778 0.222 0.000
Y85.0 Sequelae of motor-vehicle accident
0.777 0.223 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.776 0.224 0.000
M05-M14 Inflammatory polyarthropathies
0.775 0.225 0.000
I27.2 Other secondary pulmonary hypertension
0.774 0.226 0.000
X60-X84 Intentional self-harm
0.774 0.226 0.000
I46 Cardiac arrest
0.774 0.226 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.774 0.226 0.000
I72.4 Aneurysm of artery of lower extremity
0.774 0.226 0.000
M25.3 Other instability of joint
0.773 0.227 0.000
S09 Other and unspecified injuries of head
0.773 0.227 0.000
M24.2 Disorder of ligament
0.771 0.229 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.770 0.230 0.000
E07.9 Disorder of thyroid, unspecified
0.768 0.231 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.768 0.232 0.000
M80-M85 Disorders of bone density and structure
0.767 0.232 0.000
Y52 Agents primarily affecting the cardiovascular system
0.767 0.233 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.764 0.236 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.764 0.236 0.000
I44.0 Atrioventricular block, first degree
0.763 0.237 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.761 0.239 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.758 0.242 0.000
I05 Rheumatic mitral valve diseases
0.757 0.243 0.000
I42 Cardiomyopathy
0.757 0.243 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.757 0.243 0.000
Z30.2 Sterilisation
0.757 0.243 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.756 0.244 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.756 0.244 0.000
I44.7 Left bundle-branch block, unspecified
0.756 0.244 0.000
B44 Aspergillosis
0.755 0.245 0.000
M25.46 Effusion of joint (Lower leg)
0.754 0.246 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.753 0.247 0.000
F31 Bipolar affective disorder
0.753 0.247 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.750 0.249 0.000
M25.7 Osteophyte
0.749 0.251 0.000
B25-B34 Other viral diseases
0.747 0.253 0.000
I44.1 Atrioventricular block, second degree
0.747 0.253 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.744 0.255 0.000
G45.3 Amaurosis fugax
0.744 0.256 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.744 0.256 0.000
A80-A89 Viral infections of the central nervous system
0.744 0.256 0.000
Z43 Attention to artificial openings
0.744 0.256 0.000
I31 Other diseases of pericardium
0.743 0.257 0.000
E23 Hypofunction and other disorders of pituitary gland
0.742 0.258 0.000
Chapter VII Diseases of the eye and adnexa
0.742 0.258 0.000
I30 Acute pericarditis
0.742 0.258 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.742 0.258 0.000
Z45.1 Adjustment and management of infusion pump
0.742 0.258 0.000
I62 Other nontraumatic intracranial haemorrhage
0.740 0.260 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.739 0.261 0.000
B15-B19 Viral hepatitis
0.739 0.261 0.000
E40-E46 Malnutrition
0.739 0.261 0.000
B99-B99 Other infectious diseases
0.738 0.262 0.000
T92.0 Sequelae of open wound of upper limb
0.737 0.263 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.737 0.263 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.737 0.263 0.000
I33.0 Acute and subacute infective endocarditis
0.736 0.264 0.000
G43.9 Migraine, unspecified
0.736 0.264 0.000
B65-B83 Helminthiases
0.735 0.265 0.000
I25.3 Aneurysm of heart
0.735 0.265 0.000
Y57 Other and unspecified drugs and medicaments
0.734 0.266 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.733 0.267 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.733 0.267 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.732 0.268 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.732 0.268 0.000
S05 Injury of eye and orbit
0.731 0.269 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.730 0.270 0.000
I49.0 Ventricular fibrillation and flutter
0.729 0.271 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.728 0.272 0.000
S10-S19 Injuries to the neck
0.727 0.273 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.726 0.274 0.000
G45.4 Transient global amnesia
0.725 0.275 0.000
S02 Fracture of skull and facial bones
0.725 0.275 0.000
I07 Rheumatic tricuspid valve diseases
0.724 0.276 0.000
I77 Other disorders of arteries and arterioles
0.724 0.276 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.724 0.276 0.000
S01 Open wound of head
0.723 0.277 0.000
Y44.2 Anticoagulants
0.721 0.279 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.720 0.280 0.000
G41 Status epilepticus
0.720 0.280 0.000
Z33 Pregnant state, incidental
0.720 0.280 0.000
Y48 Anaesthetics and therapeutic gases
0.719 0.281 0.000
I15 Secondary hypertension
0.718 0.282 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.718 0.282 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.717 0.283 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.717 0.283 0.000
G95 Other diseases of spinal cord
0.717 0.283 0.000
Z50.6 Orthoptic training
0.717 0.283 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.717 0.283 0.000
Z50.3 Drug rehabilitation
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
M86-M90 Other osteopathies
0.716 0.284 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.716 0.284 0.000
Z54 Convalescence
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.284 0.000
I48 Atrial fibrillation and flutter
0.715 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.284 0.000
I40 Acute myocarditis
0.715 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.284 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.715 0.285 0.000
Z50.5 Speech therapy
0.715 0.285 0.000
I51.4 Myocarditis, unspecified
0.714 0.286 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.287 0.000
S06.5 Traumatic subdural haemorrhage
0.713 0.287 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.713 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
V10-V19 Pedal cyclist injured in transport accident
0.713 0.287 0.000
G47.8 Other sleep disorders
0.712 0.288 0.000
T91.1 Sequelae of fracture of spine
0.712 0.288 0.000
G40.8 Other epilepsy
0.710 0.290 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.710 0.290 0.000
G40.5 Special epileptic syndromes
0.710 0.290 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.710 0.290 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.710 0.290 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.710 0.290 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.710 0.290 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.710 0.290 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.709 0.291 0.000
I11 Hypertensive heart disease
0.709 0.291 0.000
I23.8 Other current complications following acute myocardial infarction
0.708 0.291 0.000
M24.0 Loose body in joint
0.708 0.292 0.000
T91.3 Sequelae of injury of spinal cord
0.707 0.293 0.000
M95.0 Acquired deformity of nose
0.707 0.293 0.000
M00-M03 Infectious arthropathies
0.706 0.294 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.706 0.294 0.000
B35 Dermatophytosis
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.704 0.296 0.000
M25.0 Haemarthrosis
0.704 0.296 0.000
I22 Subsequent myocardial infarction
0.703 0.297 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.702 0.297 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.702 0.297 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.702 0.297 0.000
M25.8 Other specified joint disorders
0.701 0.299 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.700 0.300 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.699 0.301 0.000
G83 Other paralytic syndromes
0.699 0.301 0.000
T98 Sequelae of other and unspecified effects of external causes
0.698 0.301 0.000
T95 Sequelae of burns, corrosions and frostbite
0.698 0.301 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.698 0.301 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.698 0.301 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.698 0.302 0.000
E00 Congenital iodine-deficiency syndrome
0.698 0.302 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.698 0.302 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.698 0.302 0.000
Z75 Problems related to medical facilities and other health care
0.697 0.303 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.696 0.304 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.696 0.304 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.696 0.304 0.000
G45.0 Vertebro-basilar artery syndrome
0.696 0.304 0.000
G30-G32 Other degenerative diseases of the nervous system
0.696 0.304 0.000
G44 Other headache syndromes
0.695 0.304 0.000
I73.8 Other specified peripheral vascular diseases
0.695 0.305 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
Z47 Other orthopaedic follow-up care
0.694 0.306 0.000
S06.2 Diffuse brain injury
0.693 0.307 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.693 0.307 0.000
M40-M43 Deforming dorsopathies
0.690 0.309 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.690 0.310 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.689 0.311 0.000
T78 Adverse effects, not elsewhere classified
0.689 0.311 0.000
I35 Nonrheumatic aortic valve disorders
0.689 0.311 0.000
I51.6 Cardiovascular disease, unspecified
0.688 0.312 0.000
I51.5 Myocardial degeneration
0.688 0.312 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.688 0.312 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.688 0.312 0.000
I51.0 Cardiac septal defect, acquired
0.688 0.312 0.000
F80-F89 Disorders of psychological development
0.687 0.313 0.000
T92.1 Sequelae of fracture of arm
0.687 0.313 0.000
M06 Other rheumatoid arthritis
0.686 0.314 0.000
E66 Obesity
0.686 0.314 0.000
Z73 Problems related to life-management difficulty
0.686 0.314 0.000
E70-E90 Metabolic disorders
0.685 0.315 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.685 0.315 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.684 0.316 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.683 0.317 0.000
G82 Paraplegia and tetraplegia
0.683 0.317 0.000
I74.5 Embolism and thrombosis of iliac artery
0.683 0.317 0.000
I28 Other diseases of pulmonary vessels
0.682 0.318 0.000
M24.9 Joint derangement, unspecified
0.681 0.319 0.000
M24.7 Protrusio acetabuli
0.681 0.319 0.000
M24.6 Ankylosis of joint
0.681 0.319 0.000
M24.5 Contracture of joint
0.681 0.319 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.681 0.319 0.000
B00 Herpesviral [herpes simplex] infections
0.680 0.320 0.000
M25.9 Joint disorder, unspecified
0.680 0.320 0.000
M25.2 Flail joint
0.680 0.320 0.000
M25.1 Fistula of joint
0.680 0.320 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.679 0.321 0.000
G70-G73 Diseases of myoneural junction and muscle
0.678 0.321 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.676 0.323 0.000
S08 Traumatic amputation of part of head
0.675 0.325 0.000
S07 Crushing injury of head
0.675 0.325 0.000
S04 Injury of cranial nerves
0.675 0.325 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.675 0.325 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.674 0.325 0.000
Z45.3 Adjustment and management of implanted hearing device
0.674 0.325 0.000
H43-H45 Disorders of vitreous body and globe
0.674 0.326 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.674 0.326 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.674 0.326 0.000
M25.78 Osteophyte (Other)
0.673 0.327 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.673 0.327 0.000
S81 Open wound of lower leg
0.672 0.327 0.000
G81.1 Spastic hemiplegia
0.672 0.328 0.000
G81.0 Flaccid hemiplegia
0.672 0.328 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.672 0.328 0.000
T14 Injury of unspecified body region
0.672 0.328 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.671 0.328 0.000
I74.8 Embolism and thrombosis of other arteries
0.671 0.328 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.671 0.328 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.671 0.328 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.671 0.328 0.000
E04.8 Other specified non-toxic goitre
0.671 0.329 0.000
E04.0 Non-toxic diffuse goitre
0.671 0.329 0.000
S32 Fracture of lumbar spine and pelvis
0.670 0.330 0.000
I49.9 Cardiac arrhythmia, unspecified
0.670 0.330 0.000
M62 Other disorders of muscle
0.669 0.331 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.668 0.332 0.000
F31.9 Bipolar affective disorder, unspecified
0.668 0.332 0.000
G95.2 Cord compression, unspecified
0.666 0.334 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.666 0.334 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.666 0.334 0.000
E61 Deficiency of other nutrient elements
0.665 0.335 0.000
E78.5 Hyperlipidaemia, unspecified
0.665 0.335 0.000
T79-T79 Certain early complications of trauma
0.664 0.335 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.664 0.336 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.664 0.336 0.000
I27.0 Primary pulmonary hypertension
0.663 0.337 0.000
S06.4 Epidural haemorrhage
0.663 0.337 0.000
M99 Biomechanical lesions, not elsewhere classified
0.663 0.337 0.000
E23.0 Hypopituitarism
0.662 0.338 0.000
Z52.3 Bone marrow donor
0.662 0.338 0.000
Z31 Procreative management
0.660 0.340 0.000
S01.2 Open wound of nose
0.659 0.341 0.000
M20.3 Other deformity of hallux (acquired)
0.659 0.341 0.000
V80-V89 Other land transport accidents
0.659 0.341 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.659 0.341 0.000
Y59 Other and unspecified vaccines and biological substances
0.658 0.342 0.000
Y58 Bacterial vaccines
0.658 0.342 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.658 0.342 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.658 0.342 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.658 0.342 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.658 0.342 0.000
M48 Other spondylopathies
0.657 0.343 0.000
I24.1 Dressler's syndrome
0.657 0.343 0.000
Z36 Antenatal screening
0.657 0.343 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.656 0.344 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.656 0.344 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.656 0.344 0.000
V20-V29 Motorcycle rider injured in transport accident
0.656 0.344 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.656 0.344 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.655 0.345 0.000
T68 Hypothermia
0.655 0.345 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.654 0.346 0.000
M25.47 Effusion of joint (Ankle and foot)
0.654 0.346 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.653 0.347 0.000
S09.9 Unspecified injury of head
0.652 0.348 0.000
S89 Other and unspecified injuries of lower leg
0.651 0.348 0.000
Y89 Sequelae of other external causes
0.650 0.350 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.650 0.350 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.650 0.350 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.649 0.351 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.648 0.352 0.000
M25.36 Other instability of joint (Lower leg)
0.648 0.352 0.000
I44.6 Other and unspecified fascicular block
0.647 0.353 0.000
I44.5 Left posterior fascicular block
0.647 0.353 0.000
I44.4 Left anterior fascicular block
0.647 0.353 0.000
I60 Subarachnoid haemorrhage
0.647 0.353 0.000
Y95 Nosocomial condition
0.647 0.353 0.000
A04 Other bacterial intestinal infections
0.647 0.353 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.646 0.354 0.000
H30-H36 Disorders of choroid and retina
0.646 0.354 0.000
I44.3 Other and unspecified atrioventricular block
0.646 0.354 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.644 0.356 0.000
F70-F79 Mental retardation
0.644 0.356 0.000
S90-S99 Injuries to the ankle and foot
0.642 0.358 0.000
G80 Infantile cerebral palsy
0.642 0.358 0.000
M22 Disorders of patella
0.641 0.359 0.000
G43.1 Migraine with aura [classical migraine]
0.639 0.361 0.000
B44.1 Other pulmonary aspergillosis
0.639 0.361 0.000
I72.8 Aneurysm of other specified arteries
0.639 0.361 0.000
Z49.0 Preparatory care for dialysis
0.638 0.362 0.000
F60-F69 Disorders of adult personality and behaviour
0.638 0.362 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.637 0.363 0.000
S20 Superficial injury of thorax
0.637 0.363 0.000
S60-S69 Injuries to the wrist and hand
0.637 0.363 0.000
E06.9 Thyroiditis, unspecified
0.637 0.363 0.000
T82.1 Mechanical complication of cardiac electronic device
0.637 0.363 0.000
Z40.9 Prophylactic surgery, unspecified
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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