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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11984041
log Bayes Factor = 12.4243
Chromosome 7   position 19,031,935  (GRCh37) Explore rs11984041 on Ensembl!
Variant rs11984041 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I65.2 Occlusion and stenosis of carotid artery
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
1.000 0.000 0.000
I21 Acute myocardial infarction
0.994 0.006 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.993 0.007 0.000
I10-I15 Hypertensive diseases
0.988 0.012 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.985 0.015 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.970 0.030 0.000
I74 Arterial embolism and thrombosis
0.969 0.031 0.000
I10 Essential (primary) hypertension
0.967 0.033 0.000
I25.2 Old myocardial infarction
0.955 0.045 0.000
I63 Cerebral infarction
0.949 0.051 0.000
I20 Angina pectoris
0.944 0.056 0.000
I77 Other disorders of arteries and arterioles
0.944 0.056 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.938 0.062 0.000
I77.1 Stricture of artery
0.934 0.066 0.000
I20.9 Angina pectoris, unspecified
0.934 0.066 0.000
I24 Other acute ischaemic heart diseases
0.922 0.078 0.000
I12 Hypertensive renal disease
0.910 0.090 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.890 0.110 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.886 0.114 0.000
I21.4 Acute subendocardial myocardial infarction
0.877 0.123 0.000
I12.0 Hypertensive renal disease with renal failure
0.866 0.134 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.856 0.144 0.000
I74.8 Embolism and thrombosis of other arteries
0.853 0.147 0.000
I70 Atherosclerosis
0.847 0.153 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.816 0.184 0.000
I74.5 Embolism and thrombosis of iliac artery
0.794 0.206 0.000
I60 Subarachnoid haemorrhage
0.789 0.211 0.000
I63.8 Other cerebral infarction
0.784 0.216 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.777 0.223 0.000
I24.1 Dressler's syndrome
0.774 0.226 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.773 0.227 0.000
I73 Other peripheral vascular diseases
0.766 0.234 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.763 0.237 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.760 0.240 0.000
I72 Other aneurysm
0.746 0.254 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.744 0.256 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.743 0.257 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.742 0.258 0.000
I24.8 Other forms of acute ischaemic heart disease
0.724 0.276 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.717 0.283 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.717 0.283 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.717 0.283 0.000
I65.1 Occlusion and stenosis of basilar artery
0.717 0.283 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.715 0.285 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.713 0.287 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.713 0.287 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.710 0.290 0.000
I77.2 Rupture of artery
0.709 0.291 0.000
I13 Hypertensive heart and renal disease
0.708 0.292 0.000
I73.9 Peripheral vascular disease, unspecified
0.708 0.292 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.706 0.294 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.701 0.299 0.000
I69 Sequelae of cerebrovascular disease
0.697 0.303 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.696 0.304 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.694 0.305 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.694 0.305 0.000
I25.3 Aneurysm of heart
0.689 0.311 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.680 0.320 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.680 0.320 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.680 0.320 0.000
I77.5 Necrosis of artery
0.677 0.323 0.000
I77.4 Coeliac artery compression syndrome
0.677 0.323 0.000
I77.3 Arterial fibromuscular dysplasia
0.677 0.323 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.675 0.325 0.000
I15 Secondary hypertension
0.671 0.329 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.666 0.334 0.000
I77.0 Arteriovenous fistula, acquired
0.657 0.343 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.649 0.351 0.000
I25.5 Ischaemic cardiomyopathy
0.636 0.364 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.625 0.375 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.619 0.381 0.000
I62 Other nontraumatic intracranial haemorrhage
0.618 0.382 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.618 0.382 0.000
I25.4 Coronary artery aneurysm
0.616 0.383 0.000
I72.2 Aneurysm of renal artery
0.616 0.384 0.000
I20.1 Angina pectoris with documented spasm
0.616 0.384 0.000
I11 Hypertensive heart disease
0.611 0.388 0.000
I70.0 Atherosclerosis of aorta
0.611 0.389 0.000
I72.8 Aneurysm of other specified arteries
0.609 0.391 0.000
I70.9 Generalised and unspecified atherosclerosis
0.608 0.392 0.000
I70.8 Atherosclerosis of other arteries
0.608 0.392 0.000
I70.1 Atherosclerosis of renal artery
0.608 0.392 0.000
I78 Diseases of capillaries
0.607 0.393 0.000
I60.8 Other subarachnoid haemorrhage
0.604 0.396 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.592 0.408 0.000
I12.9 Hypertensive renal disease without renal failure
0.586 0.413 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.582 0.418 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.582 0.418 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.570 0.430 0.000
I73.8 Other specified peripheral vascular diseases
0.566 0.434 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.566 0.434 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.566 0.434 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.566 0.434 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.566 0.434 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.557 0.443 0.000
I66.8 Occlusion and stenosis of other cerebral artery
0.557 0.443 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.557 0.443 0.000
I66.3 Occlusion and stenosis of cerebellar arteries
0.557 0.443 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.557 0.443 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.557 0.443 0.000
I69.3 Sequelae of cerebral infarction
0.550 0.450 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.549 0.451 0.000
I72.9 Aneurysm of unspecified site
0.546 0.454 0.000
I20.0 Unstable angina
0.541 0.459 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.535 0.465 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.535 0.465 0.000
I72.1 Aneurysm of artery of upper extremity
0.535 0.465 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.532 0.468 0.000
I72.3 Aneurysm of iliac artery
0.528 0.472 0.000
I99 Other and unspecified disorders of circulatory system
0.525 0.475 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.523 0.477 0.000
I23.8 Other current complications following acute myocardial infarction
0.514 0.486 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.514 0.486 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.514 0.486 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.514 0.486 0.000
I02 Rheumatic chorea
0.514 0.486 0.000
I01 Rheumatic fever with heart involvement
0.514 0.486 0.000
I00 Rheumatic fever without mention of heart involvement
0.514 0.486 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.514 0.486 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.514 0.486 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.514 0.486 0.000
I68.0 Cerebral amyloid angiopathy
0.514 0.486 0.000
I15.9 Seconday hypertension, unspecified
0.510 0.490 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.508 0.492 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.508 0.492 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.508 0.492 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.508 0.492 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.500 0.500 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.484 0.516 0.000
I79.1 Aortitis in diseases classified elsewhere
0.484 0.516 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.484 0.516 0.000
I15.8 Other secondary hypertension
0.481 0.519 0.000
I15.2 Hypertension secondary to endocrine disorders
0.481 0.519 0.000
I15.0 Renovascular hypertension
0.481 0.519 0.000
I67 Other cerebrovascular diseases
0.459 0.540 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.458 0.542 0.000
I72.4 Aneurysm of artery of lower extremity
0.457 0.543 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.449 0.551 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.448 0.552 0.000
I62.1 Nontraumatic extradural haemorrhage
0.443 0.557 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.442 0.558 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.442 0.558 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.438 0.561 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.438 0.562 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.436 0.564 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.436 0.564 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.436 0.564 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.436 0.564 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.436 0.564 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.436 0.564 0.000
I78.9 Disease of capillaries, unspecified
0.435 0.565 0.000
I61 Intracerebral haemorrhage
0.430 0.569 0.001
I05-I09 Chronic rheumatic heart diseases
0.422 0.578 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.421 0.579 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.420 0.580 0.000
I67.2 Cerebral atherosclerosis
0.419 0.581 0.000
I72.0 Aneurysm of carotid artery
0.417 0.582 0.000
I97.1 Other functional disturbances following cardiac surgery
0.413 0.587 0.000
I20.8 Other forms of angina pectoris
0.413 0.587 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.408 0.592 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.404 0.595 0.001
I69.0 Sequelae of subarachnoid haemorrhage
0.405 0.595 0.000
I15.1 Hypertension secondary to other renal disorders
0.403 0.597 0.000
I77.8 Other specified disorders of arteries and arterioles
0.402 0.597 0.001
I78.8 Other diseases of capillaries
0.396 0.603 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.383 0.617 0.000
I77.6 Arteritis, unspecified
0.382 0.618 0.001
Z95.1 Presence of aortocoronary bypass graft
0.376 0.624 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.375 0.625 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.375 0.625 0.000
I97.0 Postcardiotomy syndrome
0.375 0.625 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.369 0.631 0.000
I01.8 Other acute rheumatic heart disease
0.369 0.631 0.000
I01.2 Acute rheumatic myocarditis
0.369 0.631 0.000
I01.1 Acute rheumatic endocarditis
0.369 0.631 0.000
I01.0 Acute rheumatic pericarditis
0.369 0.631 0.000
I02.9 Rheumatic chorea without heart involvement
0.369 0.631 0.000
I02.0 Rheumatic chorea with heart involvement
0.369 0.631 0.000
I78.1 Naevus, nonneoplastic
0.360 0.640 0.000
I71 Aortic aneurysm and dissection
0.358 0.642 0.000
I21.9 Acute myocardial infarction, unspecified
0.354 0.646 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.348 0.652 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.334 0.665 0.001
I67.7 Cerebral arteritis, not elsewhere classified
0.329 0.670 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.329 0.670 0.000
I67.5 Moyamoya disease
0.329 0.670 0.000
I67.4 Hypertensive encephalopathy
0.329 0.670 0.000
I67.3 Progressive vascular leukoencephalopathy
0.329 0.670 0.000
I22 Subsequent myocardial infarction
0.316 0.683 0.001
I21.0 Acute transmural myocardial infarction of anterior wall
0.311 0.689 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.309 0.691 0.001
I61.4 Intracerebral haemorrhage in cerebellum
0.309 0.691 0.001
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.309 0.691 0.001
I61.3 Intracerebral haemorrhage in brain stem
0.308 0.691 0.001
I11.9 Hypertensive heart disease without (congestive) heart failure
0.308 0.692 0.001
I05 Rheumatic mitral valve diseases
0.306 0.694 0.000
I09 Other rheumatic heart diseases
0.305 0.695 0.000
I06 Rheumatic aortic valve diseases
0.303 0.697 0.000
I61.8 Other intracerebral haemorrhage
0.297 0.702 0.001
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.293 0.707 0.001
I28 Other diseases of pulmonary vessels
0.289 0.710 0.001
I61.5 Intracerebral haemorrhage, intraventricular
0.287 0.713 0.001
I67.0 Dissection of cerebral arteries, nonruptured
0.282 0.718 0.000
I67.8 Other specified cerebrovascular diseases
0.276 0.724 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.274 0.725 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.274 0.725 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.274 0.725 0.000
I98.0 Cardiovascular syphilis
0.274 0.725 0.000
I95 Hypotension
0.274 0.726 0.000
I67.1 Cerebral aneurysm, nonruptured
0.261 0.739 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.257 0.743 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.257 0.743 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.257 0.743 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.257 0.743 0.000
I05.1 Rheumatic mitral insufficiency
0.254 0.746 0.000
I71.0 Dissection of aorta [any part]
0.252 0.748 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.245 0.755 0.000
I07 Rheumatic tricuspid valve diseases
0.244 0.756 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.243 0.757 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.243 0.757 0.000
I63.9 Cerebral infarction, unspecified
0.243 0.757 0.000
I26 Pulmonary embolism
0.241 0.759 0.000
I22.8 Subsequent myocardial infarction of other sites
0.232 0.767 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.231 0.769 0.000
I05.0 Mitral stenosis
0.229 0.771 0.000
I09.9 Rheumatic heart disease, unspecified
0.221 0.778 0.000
I05.8 Other mitral valve diseases
0.220 0.780 0.000
I09.8 Other specified rheumatic heart diseases
0.219 0.781 0.000
I09.2 Chronic rheumatic pericarditis
0.219 0.781 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.219 0.781 0.000
I09.0 Rheumatic myocarditis
0.219 0.781 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.217 0.783 0.000
I06.8 Other rheumatic aortic valve diseases
0.217 0.783 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.217 0.783 0.000
I06.1 Rheumatic aortic insufficiency
0.217 0.783 0.000
I06.0 Rheumatic aortic stenosis
0.217 0.783 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.208 0.792 0.001
I28.1 Aneurysm of pulmonary artery
0.208 0.792 0.001
I28.0 Arteriovenous fistula of pulmonary vessels
0.208 0.792 0.001
I28.8 Other specified diseases of pulmonary vessels
0.207 0.792 0.001
I05.9 Mitral valve disease, unspecified
0.203 0.797 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.198 0.802 0.000
I95.0 Idiopathic hypotension
0.197 0.803 0.000
I95.2 Hypotension due to drugs
0.196 0.804 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.192 0.808 0.000
I95.8 Other hypotension
0.183 0.816 0.000
I95.9 Hypotension, unspecified
0.179 0.821 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.179 0.821 0.000
I05.2 Mitral stenosis with insufficiency
0.178 0.822 0.000
I07.9 Tricuspid valve disease, unspecified
0.175 0.825 0.000
I07.8 Other tricuspid valve diseases
0.175 0.825 0.000
I07.2 Tricuspid stenosis with insufficiency
0.175 0.825 0.000
I07.0 Tricuspid stenosis
0.175 0.825 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.168 0.831 0.001
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.169 0.831 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.166 0.833 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.138 0.861 0.001
Z95.8 Presence of other cardiac and vascular implants and grafts
0.138 0.862 0.000
I08 Multiple valve diseases
0.131 0.869 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.127 0.872 0.001
Z95.3 Presence of xenogenic heart valve
0.125 0.875 0.000
I07.1 Tricuspid insufficiency
0.116 0.884 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.113 0.887 0.000
K60.2 Anal fissure, unspecified
0.110 0.890 0.000
I27 Other pulmonary heart diseases
0.106 0.892 0.003
I73.0 Raynaud's syndrome
0.108 0.892 0.001
K60 Fissure and fistula of anal and rectal regions
0.103 0.897 0.000
I08.8 Other multiple valve diseases
0.101 0.899 0.000
Z95.4 Presence of other heart-valve replacement
0.099 0.900 0.000
K60.1 Chronic anal fissure
0.096 0.904 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.095 0.904 0.000
I08.9 Multiple valve disease, unspecified
0.094 0.906 0.000
I95.1 Orthostatic hypotension
0.088 0.912 0.000
K60.3 Anal fistula
0.086 0.914 0.000
K60.0 Acute anal fissure
0.085 0.915 0.000
K60.4 Rectal fistula
0.083 0.917 0.000
K60.5 Anorectal fistula
0.082 0.918 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.076 0.921 0.003
I08.2 Disorders of both aortic and tricuspid valves
0.078 0.922 0.000
I27.1 Kyphoscoliotic heart disease
0.076 0.922 0.002
I27.8 Other specified pulmonary heart diseases
0.070 0.928 0.002
I27.9 Pulmonary heart disease, unspecified
0.069 0.929 0.002
I27.2 Other secondary pulmonary hypertension
0.059 0.939 0.002
I08.0 Disorders of both mitral and aortic valves
0.055 0.945 0.000
E78.0 Pure hypercholesterolaemia
0.048 0.952 0.000
Z95.2 Presence of prosthetic heart valve
0.047 0.952 0.000
I67.9 Cerebrovascular disease, unspecified
0.037 0.961 0.003
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.038 0.961 0.001
Z95.0 Presence of cardiac pacemaker
0.027 0.973 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.020 0.980 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.019 0.981 0.000
I27.0 Primary pulmonary hypertension
0.013 0.982 0.005
Z92.2 Personal history of long-term (current) use of other medicaments
0.017 0.983 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.016 0.984 0.000
E78.2 Mixed hyperlipidaemia
0.015 0.985 0.000
E78.6 Lipoprotein deficiency
0.014 0.985 0.000
E78.3 Hyperchylomicronaemia
0.014 0.985 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.014 0.986 0.000
E78.5 Hyperlipidaemia, unspecified
0.014 0.986 0.000
N32.8 Other specified disorders of bladder
0.000 0.986 0.014
H72 Perforation of tympanic membrane
0.013 0.987 0.000
E78.1 Pure hyperglyceridaemia
0.012 0.988 0.000
N32.0 Bladder-neck obstruction
0.000 0.988 0.012
E78.4 Other hyperlipidaemia
0.012 0.988 0.000
N32 Other disorders of bladder
0.000 0.988 0.012
H72.0 Central perforation of tympanic membrane
0.011 0.988 0.000
I86 Varicose veins of other sites
0.011 0.989 0.000
E78.8 Other disorders of lipoprotein metabolism
0.011 0.989 0.000
N32.3 Diverticulum of bladder
0.000 0.989 0.011
H72.8 Other perforations of tympanic membrane
0.010 0.990 0.000
I88 Nonspecific lymphadenitis
0.010 0.990 0.000
Z36.8 Other antenatal screening
0.010 0.990 0.000
H72.2 Other marginal perforations of tympanic membrane
0.009 0.990 0.000
H72.1 Attic perforation of tympanic membrane
0.009 0.990 0.000
I86.4 Gastric varices
0.009 0.990 0.000
N32.1 Vesicointestinal fistula
0.000 0.990 0.009
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.009 0.991 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.009 0.991 0.000
I86.1 Scrotal varices
0.009 0.991 0.000
I85 Oesophageal varices
0.009 0.991 0.000
N32.4 Rupture of bladder, nontraumatic
0.000 0.991 0.009
Z36 Antenatal screening
0.009 0.991 0.000
I86.3 Vulval varices
0.008 0.992 0.000
I86.2 Pelvic varices
0.008 0.992 0.000
I86.0 Sublingual varices
0.008 0.992 0.000
I81 Portal vein thrombosis
0.008 0.992 0.000
N32.2 Vesical fistula, not elsewhere classified
0.000 0.992 0.008
I89.1 Lymphangitis
0.008 0.992 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.008 0.992 0.000
I87 Other disorders of veins
0.008 0.992 0.000
I86.8 Varicose veins of other specified sites
0.007 0.992 0.000
R04.0 Epistaxis
0.000 0.993 0.007
I88.8 Other nonspecific lymphadenitis
0.007 0.993 0.000
I88.1 Chronic lymphadenitis, except mesenteric
0.007 0.993 0.000
I88.0 Nonspecific mesenteric lymphadenitis
0.007 0.993 0.000
M51.2 Other specified intervertebral disk displacement
0.007 0.993 0.000
I83 Varicose veins of lower extremities
0.007 0.993 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.007 0.993 0.000
Z29.0 Isolation
0.007 0.993 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.007 0.993 0.000
J34.2 Deviated nasal septum
0.000 0.993 0.007
I88.9 Nonspecific lymphadenitis, unspecified
0.007 0.993 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.007 0.993 0.000
F25 Schizoaffective disorders
0.007 0.993 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.007 0.993 0.000
F25.9 Schizoaffective disorder, unspecified
0.007 0.993 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.006 0.993 0.000
I85.9 Oesophageal varices without bleeding
0.006 0.993 0.000
H65-H75 Diseases of middle ear and mastoid
0.007 0.993 0.000
F20 Schizophrenia
0.006 0.994 0.000
F29 Unspecified nonorganic psychosis
0.006 0.994 0.000
Z36.5 Antenatal screening for isoimmunisation
0.006 0.994 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.006 0.994 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.006 0.994 0.000
I82 Other venous embolism and thrombosis
0.006 0.994 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.006 0.994 0.000
F22 Persistent delusional disorders
0.006 0.994 0.000
H34.2 Other retinal artery occlusions
0.006 0.994 0.000
F23 Acute and transient psychotic disorders
0.006 0.994 0.000
H73 Other disorders of tympanic membrane
0.006 0.994 0.000
I87.9 Disorder of vein, unspecified
0.006 0.994 0.000
I87.0 Postphlebitic syndrome
0.006 0.994 0.000
G35 Multiple sclerosis
0.000 0.994 0.006
F20.9 Schizophrenia, unspecified
0.006 0.994 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.006 0.994 0.000
N32.9 Bladder disorder, unspecified
0.000 0.994 0.006
F20.0 Paranoid schizophrenia
0.005 0.994 0.000
I45.1 Other and unspecified right bundle-branch block
0.000 0.994 0.006
I87.8 Other specified disorders of veins
0.005 0.995 0.000
H69 Other disorders of Eustachian tube
0.005 0.995 0.000
F28 Other nonorganic psychotic disorders
0.005 0.995 0.000
F24 Induced delusional disorder
0.005 0.995 0.000
F21 Schizotypal disorder
0.005 0.995 0.000
H73.8 Other specified disorders of tympanic membrane
0.005 0.995 0.000
I85.0 Oesophageal varices with bleeding
0.005 0.995 0.000
F22.9 Persistent delusional disorder, unspecified
0.005 0.995 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.005 0.995 0.000
F25.8 Other schizoaffective disorders
0.005 0.995 0.000
F25.2 Schizoaffective disorder, mixed type
0.005 0.995 0.000
F25.1 Schizoaffective disorder, depressive type
0.005 0.995 0.000
F25.0 Schizoaffective disorder, manic type
0.005 0.995 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.005 0.995 0.000
H69.9 Eustachian tube disorder, unspecified
0.005 0.995 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.005 0.995 0.000
H70 Mastoiditis and related conditions
0.005 0.995 0.000
H68 Eustachian salpingitis and obstruction
0.005 0.995 0.000
H67 Otitis media in diseases classified elsewhere
0.005 0.995 0.000
F20.8 Other schizophrenia
0.005 0.995 0.000
F20.6 Simple schizophrenia
0.005 0.995 0.000
F20.5 Residual schizophrenia
0.005 0.995 0.000
F20.4 Postschizophrenic depression
0.005 0.995 0.000
F20.3 Undifferentiated schizophrenia
0.005 0.995 0.000
F20.2 Catatonic schizophrenia
0.005 0.995 0.000
F20.1 Hebephrenic schizophrenia
0.005 0.995 0.000
M51 Other intervertebral disk disorders
0.005 0.995 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.005 0.995 0.000
F22.0 Delusional disorder
0.005 0.995 0.000
H66 Suppurative and unspecified otitis media
0.005 0.995 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.005 0.995 0.000
I82.3 Embolism and thrombosis of renal vein
0.004 0.995 0.000
I82.1 Thrombophlebitis migrans
0.004 0.995 0.000
I82.0 Budd-Chiari syndrome
0.004 0.995 0.000
H65 Nonsuppurative otitis media
0.005 0.995 0.000
M51.9 Intervertebral disk disorder, unspecified
0.005 0.995 0.000
I89.0 Lymphoedema, not elsewhere classified
0.005 0.995 0.000
F22.8 Other persistent delusional disorders
0.004 0.995 0.000
J34.3 Hypertrophy of nasal turbinates
0.000 0.995 0.005
F23.8 Other acute and transient psychotic disorders
0.004 0.995 0.000
F23.3 Other acute predominantly delusional psychotic disorders
0.004 0.995 0.000
F23.2 Acute schizophrenia-like psychotic disorder
0.004 0.995 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.004 0.995 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.004 0.995 0.000
H73.1 Chronic myringitis
0.004 0.995 0.000
H73.0 Acute myringitis
0.004 0.995 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.004 0.996 0.000
H74 Other disorders of middle ear and mastoid
0.004 0.996 0.000
I87.1 Compression of vein
0.004 0.996 0.000
J34 Other disorders of nose and nasal sinuses
0.000 0.996 0.004
D23.1 Skin of eyelid, including canthus
0.000 0.996 0.004
I82.9 Embolism and thrombosis of unspecified vein
0.004 0.996 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.004 0.996 0.000
H69.0 Patulous Eustachian tube
0.004 0.996 0.000
F00 Dementia in Alzheimer's disease
0.004 0.996 0.000
Chapter V Mental and behavioural disorders
0.004 0.996 0.000
H34 Retinal vascular occlusions
0.004 0.996 0.000
H65.2 Chronic serous otitis media
0.004 0.996 0.000
I82.2 Embolism and thrombosis of vena cava
0.004 0.996 0.000
M51.4 Schmorl's nodes
0.004 0.996 0.000
H66.3 Other chronic suppurative otitis media
0.004 0.996 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.004 0.996 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.004 0.996 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.004 0.996 0.000
H71 Cholesteatoma of middle ear
0.004 0.996 0.000
H67.8 Otitis media in other diseases classified elsewhere
0.004 0.996 0.000
H67.1 Otitis media in viral diseases classified elsewhere
0.004 0.996 0.000
H67.0 Otitis media in bacterial diseases classified elsewhere
0.004 0.996 0.000
H68.1 Obstruction of Eustachian tube
0.004 0.996 0.000
H68.0 Eustachian salpingitis
0.004 0.996 0.000
H70.9 Mastoiditis, unspecified
0.004 0.996 0.000
H70.8 Other mastoiditis and related conditions
0.004 0.996 0.000
H70.2 Petrositis
0.004 0.996 0.000
H70.1 Chronic mastoiditis
0.004 0.996 0.000
H70.0 Acute mastoiditis
0.004 0.996 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.004 0.996 0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere
0.004 0.996 0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere
0.004 0.996 0.000
M51.3 Other specified intervertebral disk degeneration
0.004 0.996 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.004 0.996 0.000
H66.4 Suppurative otitis media, unspecified
0.004 0.996 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.004 0.996 0.000
H66.0 Acute suppurative otitis media
0.004 0.996 0.000
M41.9 Scoliosis, unspecified
0.004 0.996 0.000
Z36.9 Antenatal screening, unspecified
0.004 0.996 0.000
H34.8 Other retinal vascular occlusions
0.004 0.996 0.000
F60-F69 Disorders of adult personality and behaviour
0.004 0.996 0.000
H65.1 Other acute nonsuppurative otitis media
0.003 0.996 0.000
H65.0 Acute serous otitis media
0.003 0.996 0.000
F80-F89 Disorders of psychological development
0.004 0.996 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.003 0.996 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.004 0.996 0.000
H34.1 Central retinal artery occlusion
0.003 0.996 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.003 0.996 0.000
M51.8 Other specified intervertebral disk disorders
0.003 0.996 0.000
H74.1 Adhesive middle ear disease
0.003 0.997 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.003 0.997 0.000
H69.8 Other specified disorders of Eustachian tube
0.003 0.997 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.003 0.997 0.000
F02 Dementia in other diseases classified elsewhere
0.003 0.997 0.000
F60 Specific personality disorders
0.003 0.997 0.000
H65.4 Other chronic nonsuppurative otitis media
0.003 0.997 0.000
F70-F79 Mental retardation
0.003 0.997 0.000
F99-F99 Unspecified mental disorder
0.003 0.997 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.000 0.997 0.003
J34.0 Abscess, furuncle and carbuncle of nose
0.000 0.997 0.003
F44 Dissociative [conversion] disorders
0.003 0.997 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.003 0.997 0.000
H74.9 Disorder of middle ear and mastoid, unspecified
0.003 0.997 0.000
H74.0 Tympanosclerosis
0.003 0.997 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.003 0.997 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.003 0.997 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.003 0.997 0.000
S02.50 Fracture of tooth (closed)
0.003 0.997 0.000
M20.5 Other deformities of toe(s) (acquired)
0.003 0.997 0.000
Q66.3 Other congenital varus deformities of feet
0.003 0.997 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.003 0.997 0.000
H34.9 Retinal vascular occlusion, unspecified
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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