TreeWAS – Variant ID: rs1814880

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.998	0.002	0.000
I20.8 Other forms of angina pectoris	0.987	0.013	0.000
I25.2 Old myocardial infarction	0.985	0.015	0.000
I21 Acute myocardial infarction	0.950	0.050	0.000
I21.9 Acute myocardial infarction, unspecified	0.947	0.053	0.000
I24 Other acute ischaemic heart diseases	0.927	0.073	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.873	0.127	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.865	0.135	0.000
I20.0 Unstable angina	0.858	0.142	0.000
I24.1 Dressler's syndrome	0.807	0.193	0.000
I20.1 Angina pectoris with documented spasm	0.806	0.194	0.000
I23 Certain current complications following acute myocardial infarction	0.806	0.194	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.798	0.202	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.776	0.224	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.734	0.266	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.681	0.319	0.000
I23.8 Other current complications following acute myocardial infarction	0.666	0.334	0.000
I25.4 Coronary artery aneurysm	0.663	0.337	0.000
I21.4 Acute subendocardial myocardial infarction	0.599	0.401	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.578	0.422	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.578	0.422	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.578	0.422	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.578	0.422	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.578	0.422	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.578	0.422	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.578	0.422	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.572	0.427	0.000
I22 Subsequent myocardial infarction	0.546	0.454	0.000
I24.8 Other forms of acute ischaemic heart disease	0.531	0.469	0.000
I25.3 Aneurysm of heart	0.515	0.485	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.462	0.537	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.448	0.552	0.000
I25.5 Ischaemic cardiomyopathy	0.411	0.589	0.000
I22.8 Subsequent myocardial infarction of other sites	0.384	0.615	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.334	0.666	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.221	0.779	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.191	0.808	0.000
Z95.1 Presence of aortocoronary bypass graft	0.091	0.909	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.091	0.909	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.086	0.914	0.000
Z95.3 Presence of xenogenic heart valve	0.078	0.922	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.024	0.976	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.020	0.979	0.000
N81.2 Incomplete uterovaginal prolapse	0.016	0.984	0.000
N81 Female genital prolapse	0.013	0.987	0.000
M35.0 Sicca syndrome [Sjogren]	0.012	0.988	0.000
Z71.3 Dietary counselling and surveillance	0.000	0.988	0.012
N81.8 Other female genital prolapse	0.012	0.988	0.000
N81.5 Vaginal enterocele	0.012	0.988	0.000
N81.9 Female genital prolapse, unspecified	0.012	0.988	0.000
N81.0 Female urethrocele	0.011	0.989	0.000
N81.3 Complete uterovaginal prolapse	0.009	0.991	0.000
N81.6 Rectocele	0.009	0.991	0.000
S92.5 Fracture of other toe	0.009	0.991	0.000
M35 Other systemic involvement of connective tissue	0.009	0.991	0.000
S92 Fracture of foot, except ankle	0.009	0.991	0.000
S92.00 Fracture of calcaneus (closed)	0.008	0.991	0.000
S92.0 Fracture of calcaneus	0.008	0.992	0.000
S92.51 Fracture of other toe (open)	0.008	0.992	0.000
S92.50 Fracture of other toe (closed)	0.008	0.992	0.000
M35.7 Hypermobility syndrome	0.008	0.992	0.000
M35.1 Other overlap syndromes	0.007	0.993	0.000
N81.1 Cystocele	0.007	0.993	0.000
S92.2 Fracture of other tarsal bone(s)	0.007	0.993	0.000
M35.2 Behcet's disease	0.007	0.993	0.000
S92.1 Fracture of talus	0.007	0.993	0.000
S92.4 Fracture of great toe	0.007	0.993	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.006	0.994	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.006	0.994	0.000
M35.5 Multifocal fibrosclerosis	0.006	0.994	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.006	0.994	0.000
S92.9 Fracture of foot, unspecified	0.006	0.994	0.000
S92.01 Fracture of calcaneus (open)	0.006	0.994	0.000
S92.3 Fracture of metatarsal bone	0.006	0.994	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.006	0.994	0.000
M35.3 Polymyalgia rheumatica	0.006	0.994	0.000
N28.1 Cyst of kidney, acquired	0.000	0.994	0.006
M35.8 Other specified systemic involvement of connective tissue	0.006	0.994	0.000
S92.7 Multiple fractures of foot	0.006	0.994	0.000
N81.4 Uterovaginal prolapse, unspecified	0.006	0.994	0.000
S90-S99 Injuries to the ankle and foot	0.006	0.994	0.000
S92.40 Fracture of great toe (closed)	0.005	0.994	0.000
Z95.2 Presence of prosthetic heart valve	0.005	0.995	0.000
S91.0 Open wound of ankle	0.005	0.995	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.005	0.995	0.000
Z95.4 Presence of other heart-valve replacement	0.005	0.995	0.000
S92.10 Fracture of talus (closed)	0.005	0.995	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.005	0.995	0.000
C53.9 Cervix uteri, unspecified	0.000	0.995	0.005
S91 Open wound of ankle and foot	0.005	0.995	0.000
S92.11 Fracture of talus (open)	0.005	0.995	0.000
S99 Other and unspecified injuries of ankle and foot	0.005	0.995	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.005	0.995	0.000
S92.91 Fracture of foot, unspecified (open)	0.005	0.995	0.000
S92.90 Fracture of foot, unspecified (closed)	0.005	0.995	0.000
S99.9 Unspecified injury of ankle and foot	0.005	0.995	0.000
S92.31 Fracture of metatarsal bone (open)	0.005	0.995	0.000
S92.41 Fracture of great toe (open)	0.004	0.995	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.995	0.005
S97 Crushing injury of ankle and foot	0.004	0.995	0.000
S92.71 Multiple fractures of foot (open)	0.004	0.996	0.000
S92.30 Fracture of metatarsal bone (closed)	0.004	0.996	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.996	0.004
S98 Traumatic amputation of ankle and foot	0.004	0.996	0.000
S95 Injury of blood vessels at ankle and foot level	0.004	0.996	0.000
S94 Injury of nerves at ankle and foot level	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.996	0.004
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.004	0.996	0.000
E21.0 Primary hyperparathyroidism	0.000	0.996	0.004
S90 Superficial injury of ankle and foot	0.004	0.996	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.996	0.004
S93.0 Dislocation of ankle joint	0.004	0.996	0.000
S91.7 Multiple open wounds of ankle and foot	0.004	0.996	0.000
S91.2 Open wound of toe(s) with damage to nail	0.004	0.996	0.000
S92.70 Multiple fractures of foot (closed)	0.004	0.996	0.000
O82.1 Delivery by emergency Caesarean section	0.004	0.996	0.000
S99.7 Multiple injuries of ankle and foot	0.004	0.996	0.000
T18.1 Foreign body in oesophagus	0.004	0.996	0.000
S97.1 Crushing injury of toe(s)	0.004	0.996	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.004	0.996	0.000
S99.8 Other specified injuries of ankle and foot	0.004	0.996	0.000
S90.0 Contusion of ankle	0.004	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.996	0.004
E34 Other endocrine disorders	0.000	0.996	0.004
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.996	0.000
S91.1 Open wound of toe(s) without damage to nail	0.003	0.996	0.000
S97.0 Crushing injury of ankle	0.003	0.996	0.000
L03.9 Cellulitis, unspecified	0.004	0.996	0.000
S90.3 Contusion of other and unspecified parts of foot	0.003	0.996	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.996	0.004
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
E21.4 Other specified disorders of parathyroid gland	0.000	0.997	0.003
E21.2 Other hyperparathyroidism	0.000	0.997	0.003
S93.2 Rupture of ligaments at ankle and foot level	0.003	0.997	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.000	0.997	0.003
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
R05 Cough	0.000	0.997	0.003
S94.9 Injury of unspecified nerve at ankle and foot level	0.003	0.997	0.000
S94.8 Injury of other nerves at ankle and foot level	0.003	0.997	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.003	0.997	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.003	0.997	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.003	0.997	0.000
S94.1 Injury of medial plantar nerve	0.003	0.997	0.000
S94.0 Injury of lateral plantar nerve	0.003	0.997	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.003	0.997	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.003	0.997	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.003	0.997	0.000
S95.2 Injury of dorsal vein of foot	0.003	0.997	0.000
S95.1 Injury of plantar artery of foot	0.003	0.997	0.000
S95.0 Injury of dorsal artery of foot	0.003	0.997	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.003	0.997	0.000
S98.3 Traumatic amputation of other parts of foot	0.003	0.997	0.000
S98.2 Traumatic amputation of two or more toes	0.003	0.997	0.000
S98.1 Traumatic amputation of one toe	0.003	0.997	0.000
S98.0 Traumatic amputation of foot at ankle level	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.000	0.997	0.003
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.003	0.997	0.000
E34.8 Other specified endocrine disorders	0.000	0.997	0.003
S93.4 Sprain and strain of ankle	0.003	0.997	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.003	0.997	0.000
S93.5 Sprain and strain of toe(s)	0.003	0.997	0.000
W07.0 Home	0.003	0.997	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.003	0.997	0.000
S90.2 Contusion of toe(s) with damage to nail	0.003	0.997	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.997	0.003
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.997	0.003
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.997	0.003
E78.9 Disorder of lipoprotein metabolism, unspecified	0.003	0.997	0.000
S90.1 Contusion of toe(s) without damage to nail	0.003	0.997	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.997	0.003
S96.8 Injury of other muscles and tendons at ankle and foot level	0.003	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.003	0.997	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.003	0.997	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.003	0.997	0.000
Z71.8 Other specified counselling	0.000	0.997	0.003
C53 Malignant neoplasm of cervix uteri	0.000	0.997	0.003
L03.3 Cellulitis of trunk	0.003	0.997	0.000
F60.9 Personality disorder, unspecified	0.003	0.997	0.000
Z95.0 Presence of cardiac pacemaker	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.003
E34.5 Androgen resistance syndrome	0.000	0.997	0.003
E34.4 Constitutional tall stature	0.000	0.997	0.003
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.003
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.003
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.003
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.997	0.003
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
S71.1 Open wound of thigh	0.003	0.997	0.000
I72.0 Aneurysm of carotid artery	0.000	0.997	0.003
S93.3 Dislocation of other and unspecified parts of foot	0.003	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.003	0.997	0.000
J80 Adult respiratory distress syndrome	0.003	0.997	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
C90.0 Multiple myeloma	0.003	0.997	0.000
M50.2 Other cervical disk displacement	0.000	0.997	0.003
M51.9 Intervertebral disk disorder, unspecified	0.000	0.997	0.003
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.003	0.997	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.997	0.003
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.997	0.003
C53.0 Endocervix	0.000	0.997	0.003
Z71.7 Human immunodeficiency virus [HIV] counselling	0.000	0.997	0.003
Z71.5 Drug abuse counselling and surveillance	0.000	0.997	0.003
Z71.4 Alcohol abuse counselling and surveillance	0.000	0.997	0.003
Z71.0 Person consulting on behalf of another person	0.000	0.997	0.003
I72.8 Aneurysm of other specified arteries	0.000	0.997	0.003
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.000	0.997	0.003
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.997	0.000
S93.40 Sprain of unspecified ligament of ankle	0.002	0.997	0.000
G70.0 Myasthenia gravis	0.000	0.997	0.003
Z71.9 Counselling, unspecified	0.000	0.997	0.003
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.003	0.997	0.000
T51.9 Alcohol, unspecified	0.000	0.997	0.002
T51.0 Ethanol	0.000	0.998	0.002
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
C53.8 Overlapping lesion of cervix uteri	0.000	0.998	0.002
C53.1 Exocervix	0.000	0.998	0.002
T18 Foreign body in alimentary tract	0.002	0.998	0.000
H60.8 Other otitis externa	0.000	0.998	0.002
I72 Other aneurysm	0.000	0.998	0.002
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.998	0.002
E20 Hypoparathyroidism	0.000	0.998	0.002
S82.8 Fractures of other parts of lower leg	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E32 Diseases of thymus	0.000	0.998	0.002
E31 Polyglandular dysfunction	0.000	0.998	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.002
E25 Adrenogenital disorders	0.000	0.998	0.002
O82 Single delivery by Caesarean section	0.002	0.998	0.000
L91.0 Keloid scar	0.000	0.998	0.002
T18.0 Foreign body in mouth	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.002	0.998	0.000
E28 Ovarian dysfunction	0.000	0.998	0.002
T18.5 Foreign body in anus and rectum	0.002	0.998	0.000
Z71.6 Tobacco abuse counselling	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.002	0.998	0.001
J00 Acute nasopharyngitis [common cold]	0.000	0.998	0.002
I78.8 Other diseases of capillaries	0.000	0.998	0.002
T51 Toxic effect of alcohol	0.000	0.998	0.002
W07 Fall involving chair	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
E29 Testicular dysfunction	0.000	0.998	0.002
I72.2 Aneurysm of renal artery	0.000	0.998	0.002
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.998	0.002
R44.3 Hallucinations, unspecified	0.000	0.998	0.002
T18.8 Foreign body in other and multiple parts of alimentary tract	0.002	0.998	0.000
T18.4 Foreign body in colon	0.002	0.998	0.000
T18.3 Foreign body in small intestine	0.002	0.998	0.000
T18.2 Foreign body in stomach	0.002	0.998	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.998	0.002
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
I72.9 Aneurysm of unspecified site	0.000	0.998	0.002
S71.0 Open wound of hip	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
W05.0 Home	0.002	0.998	0.000
E26 Hyperaldosteronism	0.000	0.998	0.002
S82.86 Maisonneuve's fracture	0.002	0.998	0.000
C67.6 Ureteric orifice	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
S71 Open wound of hip and thigh	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
I72.1 Aneurysm of artery of upper extremity	0.000	0.998	0.002
I77.0 Arteriovenous fistula, acquired	0.000	0.998	0.002
K09.8 Other cysts of oral region, not elsewhere classified	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
W17.4 Street and highway	0.002	0.998	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.998	0.001
F52.2 Failure of genital response	0.002	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
W07.5 Trade and service area	0.002	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.002	0.998	0.000
Z89 Acquired absence of limb	0.002	0.998	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.002	0.998	0.000
S82.81 Fractures of other parts of lower leg (open)	0.002	0.998	0.000
S31.0 Open wound of lower back and pelvis	0.002	0.998	0.000
Z71.2 Person consulting for explanation of investigation findings	0.000	0.998	0.002
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.002	0.998	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.998	0.002
M87.2 Osteonecrosis due to previous trauma	0.002	0.998	0.000
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
G93.9 Disorder of brain, unspecified	0.000	0.998	0.002
T51.8 Other alcohols	0.000	0.998	0.002
T51.3 Fusel oil	0.000	0.998	0.002
T51.2 2-Propanol	0.000	0.998	0.002
T51.1 Methanol	0.000	0.998	0.002
W07.2 School, other institution and public administrative area	0.002	0.998	0.000
W07.8 Other specified place	0.002	0.998	0.000
W07.7 Farm	0.002	0.998	0.000
W07.6 Industrial and construction area	0.002	0.998	0.000
W07.4 Street and highway	0.002	0.998	0.000
W07.3 Sports and athletics area	0.002	0.998	0.000
W07.1 Residential institution	0.002	0.998	0.000
M25.86 Other specified joint disorders (Lower leg)	0.000	0.998	0.002
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.002
E29.8 Other testicular dysfunction	0.000	0.998	0.002
E29.0 Testicular hyperfunction	0.000	0.998	0.002
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.998	0.002
T18.9 Foreign body in alimentary tract, part unspecified	0.002	0.998	0.000
W11.6 Industrial and construction area	0.002	0.998	0.000
N76.2 Acute vulvitis	0.000	0.998	0.002
W05 Fall involving wheelchair	0.002	0.998	0.000
C67.1 Dome of bladder	0.000	0.998	0.002
F32.3 Severe depressive episode with psychotic symptoms	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.002	0.998	0.000
H60 Otitis externa	0.000	0.998	0.002
W17 Other fall from one level to another	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.000	0.998	0.002
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.002
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.998	0.002
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.998	0.002
I78 Diseases of capillaries	0.000	0.998	0.002
W11 Fall on and from ladder	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.000	0.998	0.001
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.001
M85.8 Other specified disorders of bone density and structure	0.002	0.998	0.000
E24 Cushing's syndrome	0.000	0.998	0.001
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
M84.2 Delayed union of fracture	0.002	0.998	0.000
N04.9 Unspecified	0.000	0.998	0.002
W11.5 Trade and service area	0.002	0.998	0.000
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.001	0.998	0.000
S71.7 Multiple open wounds of of hip and thigh	0.001	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
M77.57 Other enthesopathy of foot-Ankle/Foot	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.000	0.998	0.002
I72.3 Aneurysm of iliac artery	0.000	0.998	0.001
O81.0 Low forceps delivery	0.002	0.998	0.000
W17.5 Trade and service area	0.002	0.998	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.000	0.998	0.002
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.001	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.001	0.998	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.998	0.002
I71.0 Dissection of aorta [any part]	0.000	0.998	0.002
O82.9 Delivery by Caesarean section, unspecified	0.001	0.998	0.000
W05.9 Unspecified place	0.001	0.998	0.000
W17.6 Industrial and construction area	0.001	0.998	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.002	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.001	0.998	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.001
F60.8 Other specific personality disorders	0.001	0.998	0.000
W03.9 Unspecified place	0.001	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.001	0.998	0.000
Z89.1 Acquired absence of hand and wrist	0.001	0.998	0.000
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.001
H44.2 Degenerative myopia	0.002	0.998	0.000
H60.0 Abscess of external ear	0.000	0.998	0.001
V89.3 Person injured in unspecified nonmotor-vehicle accident, traffic	0.001	0.998	0.000
V89.1 Person injured in unspecified nonmotor-vehicle accident, nontraffic	0.001	0.998	0.000
V89.0 Person injured in unspecified motor-vehicle accident, nontraffic	0.001	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.001	0.998	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.001	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.001	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.001	0.998	0.000
D35.2 Pituitary gland	0.000	0.998	0.002
G70 Myasthenia gravis and other myoneural disorders	0.000	0.998	0.001
W03 Other fall on same level due to collision with, or pushing by, another person	0.001	0.998	0.000
W07.29 Fall involving chair; School, other institution and public administrative area; During unspecified activity	0.001	0.998	0.000
C67.3 Anterior wall of bladder	0.000	0.998	0.001
H61.0 Perichondritis of external ear	0.000	0.998	0.002
I77.8 Other specified disorders of arteries and arterioles	0.000	0.998	0.002
M84.3 Stress fracture, not elsewhere classified	0.001	0.998	0.000
O81.4 Vacuum extractor delivery	0.001	0.998	0.000
Z89.2 Acquired absence of upper limb above wrist	0.001	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.000	0.998	0.001
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.001	0.998	0.000
L53.9 Erythematous condition, unspecified	0.000	0.998	0.002
W05.8 Other specified place	0.001	0.998	0.000
W05.7 Farm	0.001	0.998	0.000
W05.6 Industrial and construction area	0.001	0.998	0.000
W05.5 Trade and service area	0.001	0.998	0.000
W05.4 Street and highway	0.001	0.998	0.000
W05.3 Sports and athletics area	0.001	0.998	0.000
W05.2 School, other institution and public administrative area	0.001	0.998	0.000
W05.1 Residential institution	0.001	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.001	0.998	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.001
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.001	0.998	0.000
G70.9 Myoneural disorder, unspecified	0.000	0.998	0.001
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
M84.8 Other disorders of continuity of bone	0.001	0.998	0.000
W11.4 Street and highway	0.001	0.998	0.000
W17.9 Unspecified place	0.001	0.998	0.000
W17.8 Other specified place	0.001	0.998	0.000
W17.0 Home	0.001	0.998	0.000
W17.7 Farm	0.001	0.998	0.000
W17.2 School, other institution and public administrative area	0.001	0.998	0.000
W17.1 Residential institution	0.001	0.998	0.000
F42 Obsessive-compulsive disorder	0.001	0.998	0.000
I77 Other disorders of arteries and arterioles	0.000	0.998	0.002
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.001	0.999	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.001	0.999	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.001	0.999	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.001	0.999	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.999	0.001
E24.3 Ectopic ACTH syndrome	0.000	0.999	0.001
E24.1 Nelson's syndrome	0.000	0.999	0.001
F02.8 Dementia in other specified diseases classified elsewhere	0.001	0.999	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.999	0.001
I78.9 Disease of capillaries, unspecified	0.000	0.999	0.001
Q60.0 Renal agenesis, unilateral	0.000	0.999	0.001
S31.1 Open wound of abdominal wall	0.001	0.999	0.000
W11.9 Unspecified place	0.001	0.999	0.000
W11.8 Other specified place	0.001	0.999	0.000
W11.0 Home	0.001	0.999	0.000
W11.7 Farm	0.001	0.999	0.000
W11.3 Sports and athletics area	0.001	0.999	0.000
W11.2 School, other institution and public administrative area	0.001	0.999	0.000
W11.1 Residential institution	0.001	0.999	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.999	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.999	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.001	0.999	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.999	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.999	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.999	0.000
M84.22 Delayed union of fracture (Upper arm)	0.001	0.999	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.999	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
E29.1 Testicular hypofunction	0.000	0.999	0.001
H60.3 Other infective otitis externa	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations