TreeWAS – Variant ID: rs1746049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.000	1.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.001	0.999
I22 Subsequent myocardial infarction	0.000	0.004	0.996
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.020	0.980
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.021	0.979
I20 Angina pectoris	0.000	0.027	0.973
I25.2 Old myocardial infarction	0.000	0.031	0.969
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.034	0.966
I25.5 Ischaemic cardiomyopathy	0.000	0.041	0.959
I20.8 Other forms of angina pectoris	0.000	0.050	0.950
I20.9 Angina pectoris, unspecified	0.000	0.089	0.911
I22.8 Subsequent myocardial infarction of other sites	0.000	0.114	0.886
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.118	0.882
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.148	0.852
I24 Other acute ischaemic heart diseases	0.000	0.173	0.827
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.213	0.787
Z95.1 Presence of aortocoronary bypass graft	0.000	0.226	0.774
I25.3 Aneurysm of heart	0.000	0.243	0.756
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.260	0.740
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.305	0.694
I23 Certain current complications following acute myocardial infarction	0.000	0.328	0.671
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.358	0.642
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.372	0.628
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.383	0.617
I24.1 Dressler's syndrome	0.000	0.408	0.592
I20.1 Angina pectoris with documented spasm	0.000	0.430	0.570
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.518	0.481
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.518	0.481
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.518	0.481
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.518	0.481
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.518	0.481
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.518	0.481
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.518	0.481
I25.4 Coronary artery aneurysm	0.001	0.530	0.469
I23.8 Other current complications following acute myocardial infarction	0.000	0.564	0.436
I24.8 Other forms of acute ischaemic heart disease	0.000	0.592	0.408
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.619	0.381
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.641	0.359
I21.4 Acute subendocardial myocardial infarction	0.000	0.646	0.354
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.659	0.341
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.679	0.321
Z95.3 Presence of xenogenic heart valve	0.000	0.758	0.242
I20.0 Unstable angina	0.000	0.772	0.228
Z95.0 Presence of cardiac pacemaker	0.000	0.787	0.213
Z95.2 Presence of prosthetic heart valve	0.000	0.908	0.092
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.940	0.060
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.960	0.040
Z95.4 Presence of other heart-valve replacement	0.001	0.961	0.038
R79.8 Other specified abnormal findings of blood chemistry	0.000	0.966	0.034
Z82.3 Family history of stroke	0.000	0.966	0.034
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.966	0.034
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.967	0.033
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.970	0.030
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.971	0.029
Z82.2 Family history of deafness and hearing loss	0.000	0.971	0.029
Z82.1 Family history of blindness and visual loss	0.000	0.975	0.025
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.976	0.024
R79 Other abnormal findings of blood chemistry	0.000	0.977	0.023
I63 Cerebral infarction	0.000	0.979	0.021
I63.9 Cerebral infarction, unspecified	0.000	0.979	0.021
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.980	0.020
L90.5 Scar conditions and fibrosis of skin	0.020	0.980	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.980	0.020
I63.8 Other cerebral infarction	0.000	0.981	0.019
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.981	0.019
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.000	0.982	0.018
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.983	0.017
R79.0 Abnormal level of blood mineral	0.000	0.983	0.017
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.000	0.983	0.017
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.984	0.016
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.984	0.016
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.985	0.015
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.985	0.015
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.985	0.015
R74 Abnormal serum enzyme levels	0.000	0.985	0.015
R74.8 Abnormal levels of other serum enzymes	0.000	0.986	0.014
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.986	0.014
R77 Other abnormalities of plasma proteins	0.000	0.986	0.014
R73 Elevated blood glucose level	0.000	0.986	0.014
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.000	0.987	0.013
R76 Other abnormal immunological findings in serum	0.000	0.987	0.013
R78 Findings of drugs and other substances, not normally found in blood	0.000	0.988	0.012
R70.1 Abnormal plasma viscosity	0.000	0.988	0.012
S60-S69 Injuries to the wrist and hand	0.000	0.988	0.012
R77.8 Other specified abnormalities of plasma proteins	0.000	0.988	0.012
S61 Open wound of wrist and hand	0.000	0.988	0.012
R71 Abnormality of red blood cells	0.000	0.989	0.011
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.000	0.989	0.011
S60 Superficial injury of wrist and hand	0.000	0.989	0.011
S64 Injury of nerves at wrist and hand level	0.000	0.989	0.011
S68 Traumatic amputation of wrist and hand	0.000	0.989	0.011
S61.8 Open wound of other parts of wrist and hand	0.000	0.989	0.011
S61.7 Multiple open wounds of wrist and hand	0.000	0.989	0.011
D36 Benign neoplasm of other and unspecified sites	0.000	0.989	0.011
R73.9 Hyperglycaemia, unspecified	0.000	0.989	0.010
S64.4 Injury of digital nerve of other finger	0.000	0.989	0.010
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.990	0.010
R73.0 Abnormal glucose tolerance test	0.000	0.990	0.010
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.990	0.010
S67 Crushing injury of wrist and hand	0.000	0.990	0.010
R74.9 Abnormal level of unspecified serum enzyme	0.000	0.990	0.010
R77.2 Abnormality of alphafetoprotein	0.000	0.990	0.010
R77.0 Abnormality of albumin	0.000	0.990	0.010
L90 Atrophic disorders of skin	0.010	0.990	0.000
R77.9 Abnormality of plasma protein, unspecified	0.000	0.990	0.010
S61.1 Open wound of finger(s) with damage to nail	0.000	0.990	0.010
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.990	0.010
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.990	0.010
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.990	0.010
S60.8 Other superficial injuries of wrist and hand	0.000	0.990	0.010
S69 Other and unspecified injuries of wrist and hand	0.000	0.990	0.010
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.990	0.010
D68.2 Hereditary deficiency of other clotting factors	0.000	0.990	0.010
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.991	0.009
W29.9 Unspecified place	0.000	0.991	0.009
D36.7 Other specified sites	0.000	0.991	0.009
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.991	0.009
R76.2 False-positive serological test for syphilis	0.000	0.991	0.009
R76.1 Abnormal reaction to tuberculin test	0.000	0.991	0.009
R76.0 Raised antibody titer	0.000	0.991	0.009
S65 Injury of blood vessels at wrist and hand level	0.000	0.991	0.009
S64.1 Injury of median nerve at wrist and hand level	0.000	0.991	0.009
R78.9 Finding of unspecified substance, not normally found in blood	0.000	0.991	0.009
R78.8 Finding of other specified substances, not normally found in blood	0.000	0.991	0.009
R78.7 Finding of abnormal level of heavy metals in blood	0.000	0.991	0.009
R78.6 Finding of steroid agent in blood	0.000	0.991	0.009
R78.5 Finding of psychotropic drug in blood	0.000	0.991	0.009
R78.4 Finding of other drugs of addictive potential in blood	0.000	0.991	0.009
R78.3 Finding of hallucinogen in blood	0.000	0.991	0.009
R78.2 Finding of cocaine in blood	0.000	0.991	0.009
R78.1 Finding of opiate drug in blood	0.000	0.991	0.009
L53.9 Erythematous condition, unspecified	0.000	0.991	0.009
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.991	0.009
R76.8 Other specified abnormal immunological findings in serum	0.000	0.991	0.009
D68.0 Von Willebrand's disease	0.000	0.991	0.009
I46.0 Cardiac arrest with successful resuscitation	0.000	0.991	0.009
D68 Other coagulation defects	0.000	0.991	0.009
S63.6 Sprain and strain of finger(s)	0.000	0.991	0.009
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.991	0.009
D68.8 Other specified coagulation defects	0.000	0.991	0.009
L90.0 Lichen sclerosus et atrophicus	0.008	0.992	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.000	0.992	0.008
S60.1 Contusion of finger(s) with damage to nail	0.000	0.992	0.008
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.992	0.008
S64.8 Injury of other nerves at wrist and hand level	0.000	0.992	0.008
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.992	0.008
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.992	0.008
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.992	0.008
R78.0 Finding of alcohol in blood	0.000	0.992	0.008
R77.1 Abnormality of globulin	0.000	0.992	0.008
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.992	0.008
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.992	0.008
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.992	0.008
S68.4 Traumatic amputation of hand at wrist level	0.000	0.992	0.008
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.992	0.008
S69.9 Unspecified injury of wrist and hand	0.000	0.992	0.008
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.992	0.008
D36.9 Benign neoplasm of unspecified site	0.000	0.992	0.008
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.992	0.008
S63.0 Dislocation of wrist	0.000	0.992	0.008
D36.0 Lymph nodes	0.000	0.992	0.008
R87.6 Abnormal cytological findings	0.008	0.992	0.000
S60.0 Contusion of finger(s) without damage to nail	0.000	0.992	0.007
S60.2 Contusion of other parts of wrist and hand	0.000	0.992	0.007
L90.9 Atrophic disorder of skin, unspecified	0.007	0.992	0.000
L90.8 Other atrophic disorders of skin	0.007	0.992	0.000
L90.6 Striae atrophicae	0.007	0.992	0.000
L90.4 Acrodermatitis chronica atrophicans	0.007	0.992	0.000
L90.3 Atrophoderma of Pasini and Pierini	0.007	0.992	0.000
L90.2 Anetoderma of Jadassohn-Pellizzari	0.007	0.992	0.000
L90.1 Anetoderma of Schweninger-Buzzi	0.007	0.992	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.992	0.008
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.992	0.007
S63.1 Dislocation finger	0.000	0.993	0.007
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.993	0.007
S63.2 Multiple dislocations of fingers	0.000	0.993	0.007
S69.8 Other specified injuries of wrist and hand	0.000	0.993	0.007
R87 Abnormal findings in specimens from female genital organs	0.007	0.993	0.000
R87.7 Abnormal histological findings	0.007	0.993	0.000
S69.7 Multiple injuries of wrist and hand	0.000	0.993	0.007
S65.5 Injury of blood vessel(s) of other finger	0.000	0.993	0.007
S62 Fracture at wrist and hand level	0.000	0.993	0.007
K04.7 Periapical abscess without sinus	0.000	0.993	0.007
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.993	0.007
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.993	0.007
N30.2 Other chronic cystitis	0.000	0.993	0.007
S62.60 Fracture of other finger (closed)	0.000	0.993	0.007
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.993	0.007
N99.3 Prolapse of vaginal vault after hysterectomy	0.007	0.993	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.993	0.007
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.993	0.007
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.993	0.007
S65.4 Injury of blood vessel(s) of thumb	0.000	0.993	0.007
S65.3 Injury of deep palmar arch	0.000	0.993	0.007
S65.2 Injury of superficial palmar arch	0.000	0.993	0.007
S65.1 Injury of radial artery at wrist and hand level	0.000	0.993	0.007
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.993	0.007
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.993	0.007
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.993	0.007
S62.6 Fracture of other finger	0.000	0.993	0.007
S64.3 Injury of digital nerve of thumb	0.000	0.993	0.007
I46.9 Cardiac arrest, unspecified	0.000	0.993	0.007
S63.5 Sprain and strain of wrist	0.000	0.993	0.007
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.993	0.007
D68.5 Primary Thrombophilia	0.000	0.993	0.007
I49.8 Other specified cardiac arrhythmias	0.000	0.993	0.007
I46 Cardiac arrest	0.000	0.993	0.007
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.993	0.006
E11.2 With renal complications	0.000	0.993	0.007
Chapter IX Diseases of the circulatory system	0.000	0.993	0.007
D68.4 Acquired coagulation factor deficiency	0.000	0.993	0.006
D68.1 Hereditary factor XI deficiency	0.000	0.993	0.006
S62.3 Fracture of other metacarpal bone	0.000	0.993	0.006
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.994	0.006
E11.4 With neurological complications	0.000	0.994	0.006
I05-I09 Chronic rheumatic heart diseases	0.000	0.994	0.006
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.994	0.006
I08 Multiple valve diseases	0.000	0.994	0.006
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.994	0.006
R87.9 Unspecified abnormal finding	0.006	0.994	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.994	0.006
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.994	0.005
H04.2 Epiphora	0.000	0.994	0.006
R87.8 Other abnormal findings	0.005	0.994	0.000
R87.5 Abnormal microbiological findings	0.005	0.994	0.000
R87.4 Abnormal immunological findings	0.005	0.994	0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.005	0.994	0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.005	0.994	0.000
R87.1 Abnormal level of hormones	0.005	0.994	0.000
R87.0 Abnormal level of enzymes	0.005	0.994	0.000
E11.6 With other specified complications	0.000	0.994	0.006
M24.4 Recurrent dislocation and subluxation of joint	0.005	0.995	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.005	0.995	0.000
S62.4 Multiple fractures of metacarpal bones	0.000	0.995	0.005
W29 Contact with other powered hand tools and household machinery	0.000	0.995	0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.995	0.005
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.005	0.995	0.000
S62.1 Fracture of other carpal bone(s)	0.000	0.995	0.005
D68.6 Other Thrombophilia	0.000	0.995	0.005
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.005	0.995	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.005	0.995	0.000
E11.8 With unspecified complications	0.000	0.995	0.005
I46.1 Sudden cardiac death, so described	0.000	0.995	0.005
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.005	0.995	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.005	0.995	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.995	0.005
I05 Rheumatic mitral valve diseases	0.000	0.995	0.005
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
S62.31 Fracture of other metacarpal bone (open)	0.000	0.995	0.005
I85.0 Oesophageal varices with bleeding	0.000	0.995	0.005
E11.5 With peripheral circulatory complications	0.000	0.995	0.005
S61.0 Open wound of finger(s) without damage to nail	0.000	0.995	0.005
S62.61 Fracture of other finger (open)	0.000	0.995	0.005
I85 Oesophageal varices	0.000	0.995	0.005
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.005	0.995	0.000
N99.1 Postprocedural urethral stricture	0.005	0.995	0.000
D66 Hereditary factor VIII deficiency	0.000	0.995	0.005
I81 Portal vein thrombosis	0.000	0.995	0.005
N99.2 Postprocedural adhesions of vagina	0.005	0.995	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.001	0.995	0.004
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.005	0.995	0.000
M24 Other specific joint derangements	0.005	0.995	0.000
E22 Hyperfunction of pituitary gland	0.000	0.995	0.005
S62.2 Fracture of first metacarpal bone	0.001	0.995	0.004
M24.54 Contracture of joint (Hand)	0.005	0.995	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.005	0.995	0.000
I00-I02 Acute rheumatic fever	0.000	0.995	0.005
I05.9 Mitral valve disease, unspecified	0.000	0.995	0.005
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.995	0.005
E11.1 With ketoacidosis	0.000	0.995	0.005
I08.9 Multiple valve disease, unspecified	0.000	0.995	0.004
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.995	0.005
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
D23.6 Skin of upper limb, including shoulder	0.005	0.995	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.995	0.004
I06 Rheumatic aortic valve diseases	0.000	0.995	0.004
K04 Diseases of pulp and periapical tissues	0.000	0.995	0.005
M24.1 Other articular cartilage disorders	0.004	0.996	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.996	0.004
I08.8 Other multiple valve diseases	0.000	0.996	0.004
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.5 Contracture of joint	0.004	0.996	0.000
E11.7 With multiple complications	0.000	0.996	0.004
H81.0 Meniere's disease	0.000	0.996	0.004
S62.8 Fracture of other and unspecified parts of wrist and hand	0.001	0.996	0.004
L53 Other erythematous conditions	0.000	0.996	0.004
E11.0 With coma	0.000	0.996	0.004
N99.5 Malfunction of external stoma of urinary tract	0.004	0.996	0.000
D62 Acute posthaemorrhagic anaemia	0.004	0.996	0.000
I09 Other rheumatic heart diseases	0.000	0.996	0.004
E22.1 Hyperprolactinaemia	0.000	0.996	0.004
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.004	0.996	0.000
I86.4 Gastric varices	0.000	0.996	0.004
S62.7 Multiple fractures of fingers	0.001	0.996	0.003
R89 Abnormal findings in specimens from other organs, systems and tissues	0.004	0.996	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.004	0.996	0.000
I86 Varicose veins of other sites	0.000	0.996	0.004
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.004	0.996	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.004	0.996	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.004	0.996	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.004	0.996	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.004	0.996	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.004	0.996	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
I85.9 Oesophageal varices without bleeding	0.000	0.996	0.004
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.004	0.996	0.000
R84.5 Abnormal microbiological findings	0.004	0.996	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.996	0.004
K01.1 Impacted teeth	0.004	0.996	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.996	0.004
W29.8 Other specified place	0.000	0.996	0.004
W29.6 Industrial and construction area	0.000	0.996	0.004
W29.0 Home	0.000	0.996	0.004
W29.7 Farm	0.000	0.996	0.004
W29.5 Trade and service area	0.000	0.996	0.004
W29.4 Street and highway	0.000	0.996	0.004
W29.3 Sports and athletics area	0.000	0.996	0.004
W29.2 School, other institution and public administrative area	0.000	0.996	0.004
W29.1 Residential institution	0.000	0.996	0.004
M24.16 Other articular cartilage disorders (Lower leg)	0.004	0.996	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.004	0.996	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.996	0.004
R86 Abnormal findings in specimens from male genital organs	0.004	0.996	0.000
R84.7 Abnormal histological findings	0.004	0.996	0.000
D68.9 Coagulation defect, unspecified	0.000	0.996	0.004
D69 Purpura and other haemorrhagic conditions	0.000	0.996	0.004
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.996	0.004
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.996	0.004
I08.0 Disorders of both mitral and aortic valves	0.000	0.996	0.004
R83 Abnormal findings in cerebrospinal fluid	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.996	0.004
M24.11 Other articular cartilage disorders (Shoulder region)	0.004	0.996	0.000
M07.3 Other psoriatic arthropathies	0.004	0.996	0.000
D67 Hereditary factor IX deficiency	0.000	0.996	0.004
I05.8 Other mitral valve diseases	0.000	0.996	0.004
I05.1 Rheumatic mitral insufficiency	0.000	0.996	0.004
M24.6 Ankylosis of joint	0.004	0.996	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.001	0.996	0.003
I49.0 Ventricular fibrillation and flutter	0.000	0.996	0.004
S62.5 Fracture of thumb	0.001	0.996	0.003
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.001	0.996	0.003
M24.9 Joint derangement, unspecified	0.004	0.996	0.000
D69.0 Allergic purpura	0.000	0.996	0.004
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.996	0.004
E22.8 Other hyperfunction of pituitary gland	0.000	0.996	0.004
S62.21 Fracture of first metacarpal bone (open)	0.001	0.996	0.003
R89.5 Abnormal microbiological findings	0.004	0.996	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.996	0.004
K04.6 Periapical abscess with sinus	0.000	0.996	0.004
R84.9 Unspecified abnormal finding	0.003	0.996	0.000
R84.8 Other abnormal findings	0.003	0.996	0.000
R84.6 Abnormal cytological findings	0.003	0.996	0.000
R84.4 Abnormal immunological findings	0.003	0.996	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.003	0.996	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.003	0.996	0.000
R84.1 Abnormal level of hormones	0.003	0.996	0.000
R84.0 Abnormal level of enzymes	0.003	0.996	0.000
I02 Rheumatic chorea	0.000	0.996	0.003
I01 Rheumatic fever with heart involvement	0.000	0.996	0.003
K04.8 Radicular cyst	0.000	0.996	0.004
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.003	0.996	0.000
I82 Other venous embolism and thrombosis	0.000	0.996	0.004
M24.17 Other articular cartilage disorders (Ankle and foot)	0.004	0.996	0.000
I05.0 Mitral stenosis	0.000	0.996	0.003
E26 Hyperaldosteronism	0.000	0.996	0.004
M24.7 Protrusio acetabuli	0.003	0.996	0.000
E20 Hypoparathyroidism	0.000	0.996	0.004
G35 Multiple sclerosis	0.004	0.996	0.000
E24 Cushing's syndrome	0.000	0.996	0.003
I07.9 Tricuspid valve disease, unspecified	0.000	0.996	0.003
I07.8 Other tricuspid valve diseases	0.000	0.996	0.003
I07.2 Tricuspid stenosis with insufficiency	0.000	0.996	0.003
I07.0 Tricuspid stenosis	0.000	0.996	0.003
E23 Hypofunction and other disorders of pituitary gland	0.000	0.996	0.003
I87 Other disorders of veins	0.000	0.996	0.003
D69.5 Secondary thrombocytopenia	0.000	0.996	0.003
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.996	0.003
I06.8 Other rheumatic aortic valve diseases	0.000	0.996	0.003
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.996	0.003
I06.1 Rheumatic aortic insufficiency	0.000	0.996	0.003
K04.3 Abnormal hard tissue formation in pulp	0.000	0.996	0.003
K04.2 Pulp degeneration	0.000	0.996	0.003
K04.1 Necrosis of pulp	0.000	0.996	0.003
R85.5 Abnormal microbiological findings	0.003	0.996	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.003	0.997	0.000
M24.18 Other articular cartilage disorders (Other)	0.003	0.997	0.000
M24.14 Other articular cartilage disorders (Hand)	0.003	0.997	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.003	0.997	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.003	0.997	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.997	0.003
M24.59 Contracture of joint (Site unspecified)	0.003	0.997	0.000
M24.58 Contracture of joint (Other)	0.003	0.997	0.000
M24.57 Contracture of joint (Ankle and foot)	0.003	0.997	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.997	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.997	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.003	0.997	0.000
K04.0 Pulpitis	0.000	0.997	0.003
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.003	0.997	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.001	0.997	0.003
K04.5 Chronic apical periodontitis	0.000	0.997	0.003
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.003	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.000	0.997	0.003
I86.1 Scrotal varices	0.000	0.997	0.003
L53.3 Other chronic figurate erythema	0.000	0.997	0.003
L53.2 Erythema marginatum	0.000	0.997	0.003
L53.1 Erythema annulare centrifugum	0.000	0.997	0.003
L53.0 Toxic erythema	0.000	0.997	0.003
N99.0 Postprocedural renal failure	0.003	0.997	0.000
I49 Other cardiac arrhythmias	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.000	0.997	0.003
E34 Other endocrine disorders	0.000	0.997	0.003
I00 Rheumatic fever without mention of heart involvement	0.000	0.997	0.003
D69.4 Other primary thrombocytopenia	0.000	0.997	0.003
I07.1 Tricuspid insufficiency	0.000	0.997	0.003
I09.8 Other specified rheumatic heart diseases	0.000	0.997	0.003
I09.2 Chronic rheumatic pericarditis	0.000	0.997	0.003
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.997	0.003
I09.0 Rheumatic myocarditis	0.000	0.997	0.003
L53.8 Other specified erythematous conditions	0.000	0.997	0.003
I06.0 Rheumatic aortic stenosis	0.000	0.997	0.003
I87.8 Other specified disorders of veins	0.000	0.997	0.003
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.997	0.003
R89.9 Unspecified abnormal finding	0.003	0.997	0.000
R89.8 Other abnormal findings	0.003	0.997	0.000
R89.6 Abnormal cytological findings	0.003	0.997	0.000
R89.4 Abnormal immunological findings	0.003	0.997	0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.003	0.997	0.000
R89.1 Abnormal level of hormones	0.003	0.997	0.000
R89.0 Abnormal level of enzymes	0.003	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.997	0.003
I86.3 Vulval varices	0.000	0.997	0.003
I86.0 Sublingual varices	0.000	0.997	0.003
R86.8 Other abnormal findings	0.003	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.997	0.003
E29 Testicular dysfunction	0.000	0.997	0.003
E05.9 Thyrotoxicosis, unspecified	0.000	0.997	0.003
R89.7 Abnormal histological findings	0.003	0.997	0.000
W29.09 Contact with other powered hand tools and household machinery; Home; During unspecified activity	0.000	0.997	0.003
W29.62 Contact with other powered hand tools and household machinery; Industrial and construction area ;While working for income	0.000	0.997	0.003
W29.82 Contact with other powered hand tools and household machinery; Other specified places ;While working for income	0.000	0.997	0.003
L29.9 Pruritus, unspecified	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.003	0.997	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.003	0.997	0.000
I82.2 Embolism and thrombosis of vena cava	0.000	0.997	0.003
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.997	0.003
I60-I69 Cerebrovascular diseases	0.000	0.997	0.003
M24.13 Other articular cartilage disorders (Forearm)	0.003	0.997	0.000
E23.0 Hypopituitarism	0.000	0.997	0.003
R85.9 Unspecified abnormal finding	0.003	0.997	0.000
R85.8 Other abnormal findings	0.003	0.997	0.000
R85.6 Abnormal cytological findings	0.003	0.997	0.000
R85.4 Abnormal immunological findings	0.003	0.997	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.003	0.997	0.000
R85.1 Abnormal level of hormones	0.003	0.997	0.000
R85.0 Abnormal level of enzymes	0.003	0.997	0.000
R86.9 Unspecified abnormal finding	0.003	0.997	0.000
R86.7 Abnormal histological findings	0.003	0.997	0.000
R86.6 Abnormal cytological findings	0.003	0.997	0.000
R86.5 Abnormal microbiological findings	0.003	0.997	0.000
R86.4 Abnormal immunological findings	0.003	0.997	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.003	0.997	0.000
R86.1 Abnormal level of hormones	0.003	0.997	0.000
R86.0 Abnormal level of enzymes	0.003	0.997	0.000
E11.3 With ophthalmic complications	0.000	0.997	0.003
M24.67 Ankylosis of joint (Ankle and foot)	0.003	0.997	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.997	0.003
D69.8 Other specified haemorrhagic conditions	0.000	0.997	0.003
D69.2 Other nonthrombocytopenic purpura	0.000	0.997	0.003
D69.1 Qualitative platelet defects	0.000	0.997	0.003
I82.8 Embolism and thrombosis of other specified veins	0.000	0.997	0.003
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.997	0.003
R83.9 Unspecified abnormal finding	0.003	0.997	0.000
R83.8 Other abnormal findings	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations