TreeWAS – Variant ID: rs2384000

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.003	0.997
I25.2 Old myocardial infarction	0.000	0.010	0.990
I21.9 Acute myocardial infarction, unspecified	0.000	0.027	0.973
I22 Subsequent myocardial infarction	0.000	0.063	0.937
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.090	0.910
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.093	0.907
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.098	0.902
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.108	0.892
Z95.4 Presence of other heart-valve replacement	0.000	0.115	0.885
I21.4 Acute subendocardial myocardial infarction	0.000	0.153	0.847
Z95.3 Presence of xenogenic heart valve	0.000	0.154	0.846
Z95.1 Presence of aortocoronary bypass graft	0.000	0.177	0.823
I25.5 Ischaemic cardiomyopathy	0.000	0.202	0.798
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.204	0.796
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.214	0.786
Z95.2 Presence of prosthetic heart valve	0.000	0.232	0.768
I20 Angina pectoris	0.000	0.238	0.762
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.245	0.755
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.252	0.748
I24 Other acute ischaemic heart diseases	0.000	0.259	0.741
I20.9 Angina pectoris, unspecified	0.000	0.261	0.739
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
I25.4 Coronary artery aneurysm	0.000	0.304	0.695
I25.3 Aneurysm of heart	0.000	0.315	0.685
I23 Certain current complications following acute myocardial infarction	0.000	0.333	0.667
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.396	0.604
I22.8 Subsequent myocardial infarction of other sites	0.000	0.396	0.603
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.402	0.598
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.412	0.588
I24.8 Other forms of acute ischaemic heart disease	0.000	0.416	0.584
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.423	0.576
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.464	0.535
I24.1 Dressler's syndrome	0.000	0.468	0.531
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.522	0.478
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.522	0.478
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.522	0.478
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.522	0.478
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.522	0.478
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.522	0.478
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.522	0.478
I23.8 Other current complications following acute myocardial infarction	0.000	0.572	0.428
I20.1 Angina pectoris with documented spasm	0.000	0.597	0.403
I20.8 Other forms of angina pectoris	0.000	0.612	0.388
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.639	0.361
Z95.0 Presence of cardiac pacemaker	0.000	0.697	0.303
I20.0 Unstable angina	0.000	0.788	0.212
M24 Other specific joint derangements	0.154	0.846	0.000
M20-M25 Other joint disorders	0.152	0.848	0.000
M24.2 Disorder of ligament	0.148	0.852	0.000
M25 Other joint disorders, not elsewhere classified	0.146	0.854	0.000
M24.0 Loose body in joint	0.146	0.854	0.000
M22 Disorders of patella	0.145	0.855	0.000
M20 Acquired deformities of fingers and toes	0.141	0.859	0.000
M24.23 Disorder of ligament (Forearm)	0.139	0.861	0.000
M25.3 Other instability of joint	0.136	0.864	0.000
M20.0 Deformity of finger(s)	0.135	0.865	0.000
M22.4 Chondromalacia patellae	0.135	0.865	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.133	0.867	0.000
M25.0 Haemarthrosis	0.131	0.869	0.000
M24.02 Loose body in joint (Upper arm)	0.130	0.870	0.000
M34 Systemic sclerosis	0.130	0.870	0.000
M25.4 Effusion of joint	0.127	0.873	0.000
M20.5 Other deformities of toe(s) (acquired)	0.126	0.874	0.000
M25.8 Other specified joint disorders	0.124	0.876	0.000
M24.07 Loose body in joint (Ankle and foot)	0.123	0.877	0.000
M21 Other acquired deformities of limbs	0.123	0.877	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.123	0.877	0.000
M25.31 Other instability of joint (Shoulder region)	0.120	0.880	0.000
M22.3 Other derangements of patella	0.120	0.880	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.120	0.880	0.000
M25.06 Haemarthrosis (Lower leg)	0.120	0.880	0.000
M24.26 Disorder of ligament (Lower leg)	0.118	0.882	0.000
M31 Other necrotising vasculopathies	0.117	0.883	0.000
M24.03 Loose body in joint (Forearm)	0.115	0.885	0.000
M25.9 Joint disorder, unspecified	0.115	0.885	0.000
M25.42 Effusion of joint (Upper arm)	0.114	0.886	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.113	0.887	0.000
M24.21 Disorder of ligament (Shoulder region)	0.112	0.888	0.000
M34.9 Systemic sclerosis, unspecified	0.111	0.889	0.000
M24.9 Joint derangement, unspecified	0.111	0.889	0.000
M24.7 Protrusio acetabuli	0.111	0.889	0.000
M24.6 Ankylosis of joint	0.111	0.889	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.110	0.890	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.110	0.890	0.000
M25.36 Other instability of joint (Lower leg)	0.110	0.890	0.000
M24.5 Contracture of joint	0.110	0.890	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.109	0.891	0.000
M22.8 Other disorders of patella	0.109	0.891	0.000
M24.01 Loose body in joint (Shoulder region)	0.108	0.891	0.000
M32 Systemic lupus erythematosus	0.108	0.892	0.000
M24.29 Disorder of ligament (Site unspecified)	0.106	0.894	0.000
M24.28 Disorder of ligament (Other)	0.106	0.894	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.106	0.894	0.000
M24.22 Disorder of ligament (Upper arm)	0.106	0.894	0.000
M24.20 Disorder of ligament (Multiple sites)	0.106	0.894	0.000
M33 Dermatopolymyositis	0.106	0.894	0.000
M25.88 Other specified joint disorders (Other)	0.105	0.894	0.000
M25.2 Flail joint	0.105	0.895	0.000
M25.1 Fistula of joint	0.105	0.895	0.000
M24.09 Loose body in joint (Site unspecified)	0.105	0.895	0.000
M24.08 Loose body in joint (Other)	0.105	0.895	0.000
M24.06 Loose body in joint-Lower leg	0.105	0.895	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.105	0.895	0.000
M24.04 Loose body in joint (Hand)	0.105	0.895	0.000
M24.00 Loose body in joint (Multiple sites)	0.105	0.895	0.000
M24.24 Disorder of ligament (Hand)	0.104	0.895	0.000
M22.1 Recurrent subluxation of patella	0.104	0.896	0.000
M22.9 Disorder of patella, unspecified	0.104	0.896	0.000
M22.0 Recurrent dislocation of patella	0.104	0.896	0.000
M25.34 Other instability of joint (Hand)	0.104	0.896	0.000
M25.33 Other instability of joint (Forearm)	0.104	0.896	0.000
M22.2 Patellofemoral disorders	0.103	0.897	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.103	0.897	0.000
M31.6 Other giant cell arteritis	0.102	0.898	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.102	0.898	0.000
M25.37 Other instability of joint (Ankle and foot)	0.101	0.898	0.000
M21.0 Valgus deformity, not elsewhere classified	0.100	0.900	0.000
M21.3 Wrist or foot drop (acquired)	0.099	0.901	0.000
M30 Polyarteritis nodosa and related conditions	0.099	0.901	0.000
M21.7 Unequal limb length (acquired)	0.098	0.902	0.000
M25.39 Other instability of joint (Site unspecified)	0.098	0.902	0.000
M25.38 Other instability of joint (Other)	0.098	0.902	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.098	0.902	0.000
M25.32 Other instability of joint (Upper arm)	0.098	0.902	0.000
M25.30 Other instability of joint (Multiple sites)	0.098	0.902	0.000
M25.86 Other specified joint disorders (Lower leg)	0.098	0.902	0.000
M34.8 Other forms of systemic sclerosis	0.097	0.903	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.096	0.903	0.000
M25.47 Effusion of joint (Ankle and foot)	0.096	0.904	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.096	0.904	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.096	0.904	0.000
M24.1 Other articular cartilage disorders	0.095	0.904	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.095	0.905	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.095	0.905	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.095	0.905	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.095	0.905	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.095	0.905	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.095	0.905	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.095	0.905	0.000
M34.1 CR(E)ST syndrome	0.095	0.905	0.000
M20.2 Hallux rigidus	0.094	0.906	0.000
M25.09 Haemarthrosis (Site unspecified)	0.094	0.906	0.000
M25.08 Haemarthrosis (Other)	0.094	0.906	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.094	0.906	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.094	0.906	0.000
M25.04 Haemarthrosis (Hand)	0.094	0.906	0.000
M25.03 Haemarthrosis (Forearm)	0.094	0.906	0.000
M25.02 Haemarthrosis (Upper arm)	0.094	0.906	0.000
M25.01 Haemarthrosis (Shoulder region)	0.094	0.906	0.000
M25.00 Haemarthrosis (Multiple sites)	0.094	0.906	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.093	0.907	0.000
M34.0 Progressive systemic sclerosis	0.093	0.907	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.093	0.907	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.093	0.907	0.000
M25.49 Effusion of joint (Site unspecified)	0.091	0.909	0.000
M25.48 Effusion of joint (Other)	0.091	0.909	0.000
M25.44 Effusion of joint (Hand)	0.091	0.909	0.000
M25.43 Effusion of joint (Forearm)	0.091	0.909	0.000
M25.41 Effusion of joint (Shoulder region)	0.091	0.909	0.000
M25.40 Effusion of joint (Multiple sites)	0.091	0.909	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.091	0.909	0.000
M21.6 Other acquired deformities of ankle and foot	0.091	0.909	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.089	0.911	0.000
M25.83 Other specified joint disorders (Forearm)	0.089	0.911	0.000
M25.82 Other specified joint disorders (Upper arm)	0.089	0.911	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.089	0.911	0.000
M20.1 Hallux valgus (acquired)	0.089	0.911	0.000
M21.9 Acquired deformity of limb, unspecified	0.088	0.911	0.000
M21.8 Other specified acquired deformities of limbs	0.088	0.911	0.000
M21.4 Flat foot [pes planus] (acquired)	0.087	0.913	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.086	0.914	0.000
Chapter IX Diseases of the circulatory system	0.000	0.914	0.086
M25.84 Other specified joint disorders (Hand)	0.085	0.915	0.000
M31.9 Necrotising vasculopathy, unspecified	0.084	0.916	0.000
M31.8 Other specified necrotising vasculopathies	0.084	0.916	0.000
M31.7 Microscopic polyangiitis	0.084	0.916	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.084	0.916	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.084	0.916	0.000
M31.2 Lethal midline granuloma	0.084	0.916	0.000
M31.1 Thrombotic microangiopathy	0.084	0.916	0.000
M31.0 Hypersensitivity angiitis	0.084	0.916	0.000
M21.2 Flexion deformity	0.083	0.917	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.083	0.917	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.917	0.083
M25.99 Joint disorder, unspecified (Site unspecified)	0.083	0.917	0.000
M25.98 Joint disorder, unspecified (Other)	0.083	0.917	0.000
M25.94 Joint disorder, unspecified (Hand)	0.083	0.917	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.083	0.917	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.083	0.917	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.083	0.917	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.083	0.917	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.083	0.917	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.082	0.918	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.081	0.918	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.081	0.919	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.081	0.919	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.081	0.919	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.081	0.919	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.081	0.919	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.081	0.919	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.081	0.919	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.081	0.919	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.081	0.919	0.000
C50 Malignant neoplasm of breast	0.081	0.919	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.080	0.920	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.080	0.920	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.079	0.920	0.000
M24.68 Ankylosis of joint (Other)	0.079	0.920	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.079	0.920	0.000
M24.66 Ankylosis of joint (Lower leg)	0.079	0.920	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.079	0.920	0.000
M24.64 Ankylosis of joint (Hand)	0.079	0.920	0.000
M24.63 Ankylosis of joint (Forearm)	0.079	0.920	0.000
M24.62 Ankylosis of joint (Upper arm)	0.079	0.920	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.079	0.920	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.079	0.920	0.000
M24.79 Protrusio acetabuli-Site unspec	0.079	0.920	0.000
M24.78 Protrusio acetabuli-Other	0.079	0.920	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.079	0.920	0.000
M24.76 Protrusio acetabuli-Lower leg	0.079	0.920	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.079	0.920	0.000
M24.74 Protrusio acetabuli-Hand	0.079	0.920	0.000
M24.73 Protrusio acetabuli-Forearm	0.079	0.920	0.000
M24.72 Protrusio acetabuli-Upper arm	0.079	0.920	0.000
M24.71 Protrusio acetabuli-Shldr region	0.079	0.920	0.000
M24.70 Protrusio acetabuli-Mult sites	0.079	0.920	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.079	0.920	0.000
M24.98 Joint derangement, unspecified (Other)	0.079	0.920	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.079	0.920	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.079	0.920	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.079	0.920	0.000
M24.94 Joint derangement, unspecified (Hand)	0.079	0.920	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.079	0.920	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.079	0.920	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.079	0.920	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.079	0.920	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.079	0.921	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.079	0.921	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.079	0.921	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.079	0.921	0.000
M24.59 Contracture of joint (Site unspecified)	0.079	0.921	0.000
M24.58 Contracture of joint (Other)	0.079	0.921	0.000
M24.57 Contracture of joint (Ankle and foot)	0.079	0.921	0.000
M24.56 Contracture of joint (Lower leg)	0.079	0.921	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.079	0.921	0.000
M24.53 Contracture of joint (Forearm)	0.079	0.921	0.000
M24.52 Contracture of joint (Upper arm)	0.079	0.921	0.000
M24.51 Contracture of joint (Shoulder region)	0.079	0.921	0.000
M24.50 Contracture of joint (Multiple sites)	0.079	0.921	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.078	0.921	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.078	0.921	0.000
M36.3 Arthropathy in other blood disorders	0.078	0.921	0.000
M36.2 Haemophilic arthropathy	0.078	0.921	0.000
M36.1 Arthropathy in neoplastic disease	0.078	0.921	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.078	0.921	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.078	0.922	0.000
M32.8 Other forms of systemic lupus erythematosus	0.078	0.922	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.078	0.922	0.000
M21.1 Varus deformity, not elsewhere classified	0.078	0.922	0.000
M24.54 Contracture of joint (Hand)	0.078	0.922	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.077	0.923	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.077	0.923	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.077	0.923	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.077	0.923	0.000
I08 Multiple valve diseases	0.000	0.923	0.077
M33.9 Dermatopolymyositis, unspecified	0.076	0.924	0.000
M33.2 Polymyositis	0.076	0.924	0.000
M33.0 Juvenile dermatomyositis	0.076	0.924	0.000
M25.19 Fistula of joint (Site unspecified)	0.075	0.924	0.000
M25.18 Fistula of joint (Other)	0.075	0.924	0.000
M25.17 Fistula of joint (Ankle and foot)	0.075	0.924	0.000
M25.16 Fistula of joint (Lower leg)	0.075	0.924	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.075	0.924	0.000
M25.14 Fistula of joint (Hand)	0.075	0.924	0.000
M25.13 Fistula of joint (Forearm)	0.075	0.924	0.000
M25.12 Fistula of joint (Upper arm)	0.075	0.924	0.000
M25.11 Fistula of joint (Shoulder region)	0.075	0.924	0.000
M25.10 Fistula of joint (Multiple sites)	0.075	0.924	0.000
M25.29 Flail joint (Site unspecified)	0.075	0.924	0.000
M25.28 Flail joint (Other)	0.075	0.924	0.000
M25.27 Flail joint (Ankle and foot)	0.075	0.924	0.000
M25.26 Flail joint (Lower leg)	0.075	0.924	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.075	0.924	0.000
M25.24 Flail joint (Hand)	0.075	0.924	0.000
M25.23 Flail joint (Forearm)	0.075	0.924	0.000
M25.22 Flail joint (Upper arm)	0.075	0.924	0.000
M25.21 Flail joint (Shoulder region)	0.075	0.924	0.000
M25.20 Flail joint (Multiple sites)	0.075	0.924	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.075	0.925	0.000
C50.9 Breast, unspecified	0.074	0.926	0.000
M25.46 Effusion of joint (Lower leg)	0.074	0.926	0.000
M33.1 Other dermatomyositis	0.073	0.927	0.000
C50.1 Central portion of breast	0.073	0.927	0.000
C50.5 Lower-outer quadrant of breast	0.073	0.927	0.000
C71 Malignant neoplasm of brain	0.073	0.927	0.000
I05 Rheumatic mitral valve diseases	0.000	0.928	0.072
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.072	0.928	0.000
M30.0 Polyarteritis nodosa	0.072	0.928	0.000
I10-I15 Hypertensive diseases	0.000	0.928	0.072
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.072	0.928	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.072	0.928	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.072	0.928	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.072	0.928	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.072	0.928	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.072	0.928	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.072	0.928	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.072	0.928	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.071	0.929	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.071	0.929	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.071	0.929	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.071	0.929	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.071	0.929	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.071	0.929	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.071	0.929	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.071	0.929	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.071	0.929	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.071	0.929	0.000
C50-C50 Malignant neoplasm of breast	0.071	0.929	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.071	0.929	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.071	0.929	0.000
M30.2 Juvenile polyarteritis	0.071	0.929	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.071	0.929	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.070	0.929	0.000
M21.78 Unequal limb length (acquired)-Other	0.070	0.929	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.070	0.929	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.070	0.929	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.070	0.929	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.070	0.929	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.070	0.929	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.070	0.929	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.070	0.929	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.069	0.931	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.069	0.931	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.069	0.931	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.069	0.931	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.069	0.931	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.069	0.931	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.069	0.931	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.069	0.931	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.069	0.931	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.069	0.931	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.069	0.931	0.000
M24.18 Other articular cartilage disorders (Other)	0.069	0.931	0.000
M24.14 Other articular cartilage disorders (Hand)	0.069	0.931	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.069	0.931	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.069	0.931	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.069	0.931	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.931	0.069
C71.9 Brain, unspecified	0.068	0.932	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.067	0.932	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.933	0.067
C50.8 Overlapping lesion of breast	0.067	0.933	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.933	0.067
C50.4 Upper-outer quadrant of breast	0.066	0.934	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.065	0.935	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.065	0.935	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.065	0.935	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.065	0.935	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.065	0.935	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.065	0.935	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.065	0.935	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.065	0.935	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.065	0.935	0.000
Chapter II Neoplasms	0.065	0.935	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.935	0.065
C71.2 Temporal lobe	0.064	0.936	0.000
M20.3 Other deformity of hallux (acquired)	0.064	0.936	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.064	0.936	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.064	0.936	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.064	0.936	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.064	0.936	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.064	0.936	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.064	0.936	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.064	0.936	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.064	0.936	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.064	0.936	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.064	0.936	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.064	0.936	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.064	0.936	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.064	0.936	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.064	0.936	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.064	0.936	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.064	0.936	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.064	0.936	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.064	0.936	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.064	0.936	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.064	0.936	0.000
I73 Other peripheral vascular diseases	0.000	0.936	0.064
I10 Essential (primary) hypertension	0.000	0.936	0.064
M25.7 Osteophyte	0.063	0.937	0.000
C71.1 Frontal lobe	0.063	0.937	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.937	0.063
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.063	0.937	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.063	0.937	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.063	0.937	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.063	0.937	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.063	0.937	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.063	0.937	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.063	0.937	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.063	0.937	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.063	0.937	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.063	0.937	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.062	0.937	0.000
C50.0 Nipple and areola	0.062	0.938	0.000
I00-I02 Acute rheumatic fever	0.000	0.938	0.062
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.061	0.938	0.000
C50.3 Lower-inner quadrant of breast	0.062	0.938	0.000
C71.8 Overlapping lesion of brain	0.061	0.939	0.000
C51-C58 Malignant neoplasms of female genital organs	0.061	0.939	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.060	0.939	0.000
I05.0 Mitral stenosis	0.000	0.940	0.060
M31.3 Wegener's granulomatosis	0.060	0.940	0.000
M21.29 Flexion deformity (Site unspecified)	0.060	0.940	0.000
M21.28 Flexion deformity (Other)	0.060	0.940	0.000
M21.26 Flexion deformity (Lower leg)	0.060	0.940	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.060	0.940	0.000
M21.24 Flexion deformity (Hand)	0.060	0.940	0.000
M21.23 Flexion deformity (Forearm)	0.060	0.940	0.000
M21.22 Flexion deformity (Upper arm)	0.060	0.940	0.000
M21.21 Flexion deformity (Shoulder region)	0.060	0.940	0.000
M21.20 Flexion deformity (Multiple sites)	0.060	0.940	0.000
I06 Rheumatic aortic valve diseases	0.000	0.940	0.059
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.059	0.941	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.059	0.941	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.059	0.941	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.059	0.941	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.059	0.941	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.059	0.941	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.059	0.941	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.059	0.941	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.059	0.941	0.000
I73.0 Raynaud's syndrome	0.000	0.942	0.058
D37-D48 Neoplasms of uncertain or unknown behaviour	0.058	0.942	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.058	0.942	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.943	0.057
D41.4 Bladder	0.057	0.943	0.000
I12 Hypertensive renal disease	0.000	0.943	0.057
D00-D09 In situ neoplasms	0.057	0.943	0.000
C50.6 Axillary tail of breast	0.057	0.943	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.056	0.943	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.056	0.944	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.056	0.944	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.056	0.944	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.056	0.944	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.056	0.944	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.056	0.944	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.056	0.944	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.056	0.944	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.056	0.944	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.056	0.944	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.056	0.944	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.944	0.056
C55 Malignant neoplasm of uterus, part unspecified	0.056	0.944	0.000
C71.4 Occipital lobe	0.055	0.944	0.000
I09 Other rheumatic heart diseases	0.000	0.945	0.055
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.055	0.945	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.945	0.055
M21.27 Flexion deformity (Ankle and foot)	0.055	0.945	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.055	0.945	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.946	0.054
M25.72 Osteophyte (Upper arm)	0.054	0.946	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.054	0.946	0.000
C69 Malignant neoplasm of eye and adnexa	0.054	0.946	0.000
M25.74 Osteophyte (Hand)	0.054	0.946	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.053	0.946	0.000
C71.3 Parietal lobe	0.053	0.947	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.947	0.053
C56 Malignant neoplasm of ovary	0.053	0.947	0.000
C71.7 Brain stem	0.052	0.948	0.000
C71.6 Cerebellum	0.052	0.948	0.000
C71.5 Cerebral ventricle	0.052	0.948	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.052	0.948	0.000
I05.8 Other mitral valve diseases	0.000	0.948	0.052
C71.0 Cerebrum, except lobes and ventricles	0.052	0.948	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.948	0.052
D04 Carcinoma in situ of skin	0.052	0.948	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.051	0.948	0.000
I13 Hypertensive heart and renal disease	0.000	0.948	0.052
M25.78 Osteophyte (Other)	0.052	0.948	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.052	0.948	0.000
D48.1 Connective and other soft tissue	0.051	0.949	0.000
I71 Aortic aneurysm and dissection	0.000	0.949	0.050
C50.2 Upper-inner quadrant of breast	0.051	0.949	0.000
C18.7 Sigmoid colon	0.050	0.950	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.950	0.050
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.049	0.950	0.000
C70 Malignant neoplasm of meninges	0.049	0.950	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.049	0.951	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.951	0.049
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.049	0.951	0.000
I07.1 Tricuspid insufficiency	0.000	0.951	0.049
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.952	0.048
I08.8 Other multiple valve diseases	0.000	0.952	0.048
C49.3 Connective and soft tissue of thorax	0.048	0.952	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations