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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117019691
log Bayes Factor = 21.5576
Chromosome 16   position 57,505,625  (GRCh37) Explore rs117019691 on Ensembl!
Variant rs117019691 is part of Cluster X0284

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.999 0.001 0.000
M20 Acquired deformities of fingers and toes
0.998 0.002 0.000
M25 Other joint disorders, not elsewhere classified
0.995 0.005 0.000
S50-S59 Injuries to the elbow and forearm
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
M45-M49 Spondylopathies
0.993 0.007 0.000
S80-S89 Injuries to the knee and lower leg
0.989 0.011 0.000
M20.1 Hallux valgus (acquired)
0.989 0.011 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.988 0.012 0.000
M47 Spondylosis
0.987 0.013 0.000
M47.9 Spondylosis, unspecified
0.985 0.015 0.000
M25.5 Pain in joint
0.983 0.017 0.000
S52 Fracture of forearm
0.978 0.022 0.000
I51 Complications and ill-defined descriptions of heart disease
0.977 0.023 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.977 0.023 0.000
I25.2 Old myocardial infarction
0.970 0.030 0.000
H02 Other disorders of eyelid
0.969 0.031 0.000
Chapter V Mental and behavioural disorders
0.963 0.037 0.000
I51.8 Other ill-defined heart diseases
0.958 0.042 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.953 0.047 0.000
I34 Nonrheumatic mitral valve disorders
0.952 0.048 0.000
S52.0 Fracture of upper end of ulna
0.952 0.048 0.000
H25-H28 Disorders of lens
0.950 0.050 0.000
I20 Angina pectoris
0.944 0.056 0.000
H04 Disorders of lachrymal system
0.944 0.056 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.941 0.059 0.000
M50-M54 Other dorsopathies
0.939 0.061 0.000
S82 Fracture of lower leg, including ankle
0.935 0.065 0.000
H53-H54 Visual disturbances and blindness
0.934 0.066 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.929 0.071 0.000
M35 Other systemic involvement of connective tissue
0.924 0.076 0.000
H25 Senile cataract
0.924 0.076 0.000
I10-I15 Hypertensive diseases
0.923 0.077 0.000
M70-M79 Other soft tissue disorders
0.922 0.078 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.919 0.081 0.000
I34.0 Mitral (valve) insufficiency
0.918 0.082 0.000
H04.2 Epiphora
0.912 0.088 0.000
M80-M85 Disorders of bone density and structure
0.910 0.090 0.000
M25.51 Pain in joint (Shoulder region)
0.909 0.091 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.907 0.093 0.000
H30-H36 Disorders of choroid and retina
0.904 0.096 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.903 0.097 0.000
M20.5 Other deformities of toe(s) (acquired)
0.902 0.098 0.000
S52.00 Fracture of upper end of ulna (closed)
0.900 0.100 0.000
I21 Acute myocardial infarction
0.898 0.102 0.000
M25.56 Pain in joint (Lower leg)
0.894 0.106 0.000
M79.6 Pain in limb
0.888 0.112 0.000
I10 Essential (primary) hypertension
0.888 0.112 0.000
M25.53 Pain in joint (Forearm)
0.888 0.112 0.000
H54 Blindness and low vision
0.879 0.121 0.000
T79-T79 Certain early complications of trauma
0.876 0.124 0.000
H25.8 Other senile cataract
0.874 0.126 0.000
H02.8 Other specified disorders of eyelid
0.873 0.127 0.000
S81 Open wound of lower leg
0.870 0.130 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.862 0.138 0.000
S51 Open wound of forearm
0.861 0.139 0.000
I51.7 Cardiomegaly
0.858 0.142 0.000
M35.3 Polymyalgia rheumatica
0.856 0.144 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.855 0.145 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.855 0.145 0.000
S52.01 Fracture of upper end of ulna (open)
0.853 0.147 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.853 0.147 0.000
M54 Dorsalgia
0.853 0.147 0.000
S50 Superficial injury of forearm
0.850 0.150 0.000
M31 Other necrotising vasculopathies
0.847 0.153 0.000
H02.3 Blepharochalasis
0.843 0.157 0.000
S82.6 Fracture of lateral malleolus
0.840 0.160 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.838 0.162 0.000
T93 Sequelae of injuries of lower limb
0.836 0.164 0.000
H25.9 Senile cataract, unspecified
0.836 0.164 0.000
M25.7 Osteophyte
0.832 0.168 0.000
I24 Other acute ischaemic heart diseases
0.832 0.168 0.000
M51 Other intervertebral disk disorders
0.830 0.170 0.000
H33 Retinal detachments and breaks
0.825 0.175 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.823 0.177 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.822 0.178 0.000
F30-F39 Mood [affective] disorders
0.822 0.178 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.822 0.178 0.000
I60-I69 Cerebrovascular diseases
0.821 0.179 0.000
M25.8 Other specified joint disorders
0.821 0.179 0.000
S00-S09 Injuries to the head
0.820 0.180 0.000
M65-M68 Disorders of synovium and tendon
0.816 0.184 0.000
I20.0 Unstable angina
0.815 0.185 0.000
F60-F69 Disorders of adult personality and behaviour
0.814 0.186 0.000
I44 Atrioventricular and left bundle-branch block
0.813 0.187 0.000
I05-I09 Chronic rheumatic heart diseases
0.812 0.188 0.000
Chapter VI Diseases of the nervous system
0.812 0.188 0.000
H02.9 Disorder of eyelid, unspecified
0.812 0.188 0.000
M79.66 Pain in limb (Lower leg)
0.811 0.189 0.000
M20.4 Other hammer toe(s) (acquired)
0.811 0.189 0.000
S80 Superficial injury of lower leg
0.810 0.190 0.000
M25.3 Other instability of joint
0.808 0.192 0.000
S40-S49 Injuries to the shoulder and upper arm
0.807 0.193 0.000
M80 Osteoporosis with pathological fracture
0.805 0.195 0.000
H02.5 Other disorders affecting eyelid function
0.805 0.195 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.803 0.197 0.000
M20.0 Deformity of finger(s)
0.803 0.197 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.803 0.197 0.000
I71 Aortic aneurysm and dissection
0.803 0.197 0.000
S82.4 Fracture of fibula alone
0.801 0.199 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.800 0.200 0.000
I21.4 Acute subendocardial myocardial infarction
0.800 0.200 0.000
M25.52 Pain in joint (Upper arm)
0.799 0.201 0.000
M79.8 Other specified soft tissue disorders
0.799 0.201 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.799 0.201 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.795 0.205 0.000
M24 Other specific joint derangements
0.795 0.205 0.000
M84 Disorders of continuity of bone
0.793 0.207 0.000
S82.8 Fractures of other parts of lower leg
0.791 0.209 0.000
I20.9 Angina pectoris, unspecified
0.790 0.210 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.787 0.213 0.000
I74 Arterial embolism and thrombosis
0.787 0.213 0.000
S20-S29 Injuries to the thorax
0.785 0.214 0.000
T92 Sequelae of injuries of upper limb
0.785 0.215 0.000
M79.62 Pain in limb (Upper arm)
0.783 0.217 0.000
I60 Subarachnoid haemorrhage
0.783 0.217 0.000
M21 Other acquired deformities of limbs
0.783 0.217 0.000
Q21 Congenital malformations of cardiac septa
0.782 0.218 0.000
H33.0 Retinal detachment with retinal break
0.779 0.221 0.000
I20.1 Angina pectoris with documented spasm
0.776 0.224 0.000
S52.6 Fracture of lower end of both ulna and radius
0.776 0.224 0.000
F20 Schizophrenia
0.776 0.224 0.000
I72 Other aneurysm
0.776 0.224 0.000
H02.1 Ectropion of eyelid
0.774 0.226 0.000
H55-H59 Other disorders of eye and adnexa
0.774 0.226 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.774 0.226 0.000
I70 Atherosclerosis
0.773 0.227 0.000
H04.1 Other disorders of lachrymal gland
0.772 0.228 0.000
M25.77 Osteophyte (Ankle and foot)
0.772 0.228 0.000
S82.60 Fracture of lateral malleolus (closed)
0.772 0.228 0.000
S52.2 Fracture of shaft of ulna
0.769 0.231 0.000
M47.1 Other spondylosis with myelopathy
0.768 0.232 0.000
H02.4 Ptosis of eyelid
0.767 0.233 0.000
H36 Retinal disorders in diseases classified elsewhere
0.767 0.233 0.000
I21.9 Acute myocardial infarction, unspecified
0.764 0.236 0.000
I31 Other diseases of pericardium
0.764 0.236 0.000
F80-F89 Disorders of psychological development
0.764 0.236 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.761 0.239 0.000
S90-S99 Injuries to the ankle and foot
0.757 0.243 0.000
M48 Other spondylopathies
0.755 0.245 0.000
H54.7 Unspecified visual loss
0.753 0.247 0.000
H54.9 Unspecified visual impairment (binocular)
0.752 0.248 0.000
I33 Acute and subacute endocarditis
0.751 0.249 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.751 0.249 0.000
M51.2 Other specified intervertebral disk displacement
0.751 0.249 0.000
S51.0 Open wound of elbow
0.750 0.250 0.000
F31 Bipolar affective disorder
0.749 0.251 0.000
S81.0 Open wound of knee
0.748 0.252 0.000
M25.57 Pain in joint (Ankle and foot)
0.746 0.254 0.000
M54.9 Dorsalgia, unspecified
0.745 0.255 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.745 0.255 0.000
S10-S19 Injuries to the neck
0.742 0.258 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.741 0.259 0.000
I73 Other peripheral vascular diseases
0.740 0.260 0.000
M34 Systemic sclerosis
0.740 0.260 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.739 0.261 0.000
M00-M03 Infectious arthropathies
0.739 0.261 0.000
M25.50 Pain in joint (Multiple sites)
0.739 0.261 0.000
S52.5 Fracture of lower end of radius
0.738 0.262 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.738 0.262 0.000
I44.7 Left bundle-branch block, unspecified
0.737 0.263 0.000
H10-H13 Disorders of conjunctiva
0.736 0.264 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.734 0.265 0.000
F25 Schizoaffective disorders
0.734 0.266 0.000
H54.0 Blindness, both eyes
0.734 0.266 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.732 0.268 0.000
Q60-Q64 Congenital malformations of the urinary system
0.732 0.268 0.000
M79.63 Pain in limb (Forearm)
0.730 0.270 0.000
S52.8 Fracture of other parts of forearm
0.730 0.270 0.000
S00 Superficial injury of head
0.729 0.271 0.000
M22 Disorders of patella
0.728 0.271 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.728 0.272 0.000
F29 Unspecified nonorganic psychosis
0.727 0.273 0.000
I22 Subsequent myocardial infarction
0.727 0.273 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.727 0.273 0.000
G90-G99 Other disorders of the nervous system
0.727 0.273 0.000
M46 Other inflammatory spondylopathies
0.726 0.274 0.000
Q21.1 Atrial septal defect
0.725 0.275 0.000
M91-M94 Chondropathies
0.724 0.276 0.000
T93.2 Sequelae of other fractures of lower limb
0.724 0.276 0.000
H18 Other disorders of cornea
0.723 0.277 0.000
I78 Diseases of capillaries
0.720 0.279 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.719 0.281 0.000
I20.8 Other forms of angina pectoris
0.718 0.282 0.000
I47 Paroxysmal tachycardia
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.716 0.284 0.000
M35.0 Sicca syndrome [Sjogren]
0.716 0.284 0.000
F22 Persistent delusional disorders
0.715 0.285 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.714 0.286 0.000
M25.9 Joint disorder, unspecified
0.714 0.286 0.000
M25.2 Flail joint
0.714 0.286 0.000
M25.1 Fistula of joint
0.714 0.286 0.000
M25.0 Haemarthrosis
0.714 0.286 0.000
S82.2 Fracture of shaft of tibia
0.713 0.287 0.000
S59 Other and unspecified injuries of forearm
0.713 0.287 0.000
S58 Traumatic amputation of forearm
0.713 0.287 0.000
S57 Crushing injury of forearm
0.713 0.287 0.000
S56 Injury of muscle and tendon at forearm level
0.713 0.287 0.000
S55 Injury of blood vessels at forearm level
0.713 0.287 0.000
S54 Injury of nerves at forearm level
0.713 0.287 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.713 0.287 0.000
I25.5 Ischaemic cardiomyopathy
0.713 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.287 0.000
I48 Atrial fibrillation and flutter
0.712 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.287 0.000
I40 Acute myocarditis
0.712 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.287 0.000
I37 Pulmonary valve disorders
0.712 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.287 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.287 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.712 0.288 0.000
M49 Spondylopathies in diseases classified elsewhere
0.712 0.288 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.711 0.289 0.000
M31.3 Wegener's granulomatosis
0.711 0.289 0.000
S88 Traumatic amputation of lower leg
0.709 0.291 0.000
S87 Crushing injury of lower leg
0.709 0.291 0.000
S86 Injury of muscle and tendon at lower leg level
0.709 0.291 0.000
S85 Injury of blood vessels at lower leg level
0.709 0.291 0.000
S84 Injury of nerves at lower leg level
0.709 0.291 0.000
H05 Disorders of orbit
0.708 0.292 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.708 0.292 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.708 0.292 0.000
F60 Specific personality disorders
0.707 0.293 0.000
M54.4 Lumbago with sciatica
0.706 0.294 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.706 0.294 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.706 0.294 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.706 0.294 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.706 0.294 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.706 0.294 0.000
S50.8 Other superficial injuries of forearm
0.706 0.294 0.000
M25.58 Pain in joint (Other)
0.705 0.295 0.000
S82.40 Fracture of fibula alone (closed)
0.704 0.296 0.000
H40-H42 Glaucoma
0.704 0.296 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.703 0.297 0.000
H53 Visual disturbances
0.702 0.298 0.000
I35 Nonrheumatic aortic valve disorders
0.702 0.298 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.701 0.299 0.000
S52.9 Fracture of forearm, part unspecified
0.701 0.299 0.000
S52.7 Multiple fractures of forearm
0.701 0.299 0.000
S52.4 Fracture of shafts of both ulna and radius
0.701 0.299 0.000
S52.3 Fracture of shaft of radius
0.701 0.299 0.000
S70-S79 Injuries to the hip and thigh
0.701 0.299 0.000
I51.6 Cardiovascular disease, unspecified
0.700 0.299 0.000
I51.5 Myocardial degeneration
0.700 0.299 0.000
I51.4 Myocarditis, unspecified
0.700 0.299 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.700 0.299 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.700 0.299 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.700 0.299 0.000
I51.0 Cardiac septal defect, acquired
0.700 0.299 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.700 0.300 0.000
M45 Ankylosing spondylitis
0.700 0.300 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.700 0.300 0.000
S81.9 Open wound of lower leg, part unspecified
0.699 0.300 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.699 0.300 0.000
S60-S69 Injuries to the wrist and hand
0.699 0.301 0.000
G70-G73 Diseases of myoneural junction and muscle
0.699 0.301 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.699 0.301 0.000
M47.2 Other spondylosis with radiculopathy
0.699 0.301 0.000
I46 Cardiac arrest
0.698 0.302 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.697 0.303 0.000
M54.3 Sciatica
0.697 0.303 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.695 0.305 0.000
M25.59 Pain in joint (Site unspecified)
0.695 0.305 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.695 0.305 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.694 0.305 0.000
H02.2 Lagophthalmos
0.694 0.305 0.000
I11 Hypertensive heart disease
0.694 0.306 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.691 0.309 0.000
F70-F79 Mental retardation
0.691 0.309 0.000
H25.1 Senile nuclear cataract
0.691 0.309 0.000
M25.86 Other specified joint disorders (Lower leg)
0.689 0.310 0.000
T66-T78 Other and unspecified effects of external causes
0.689 0.311 0.000
F99-F99 Unspecified mental disorder
0.688 0.312 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.687 0.313 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.687 0.313 0.000
I49 Other cardiac arrhythmias
0.687 0.313 0.000
M53 Other dorsopathies, not elsewhere classified
0.686 0.314 0.000
M86-M90 Other osteopathies
0.686 0.314 0.000
M76 Enthesopathies of lower limb, excluding foot
0.685 0.315 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.684 0.316 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.684 0.316 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.682 0.318 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.682 0.318 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.682 0.318 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.682 0.318 0.000
T93.1 Sequelae of fracture of femur
0.682 0.318 0.000
S52.1 Fracture of upper end of radius
0.681 0.319 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.681 0.319 0.000
H27 Other disorders of lens
0.681 0.319 0.000
M79.1 Myalgia
0.680 0.320 0.000
Q50-Q56 Congenital malformations of genital organs
0.679 0.321 0.000
Chapter XXII Codes for special purposes
0.678 0.321 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.677 0.323 0.000
T79.8 Other early complications of trauma
0.677 0.323 0.000
H04.9 Disorder of lachrymal system, unspecified
0.677 0.323 0.000
H04.8 Other disorders of lachrymal system
0.677 0.323 0.000
H04.6 Other changes in lachrymal passages
0.677 0.323 0.000
H04.4 Chronic inflammation of lachrymal passages
0.677 0.323 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.677 0.323 0.000
H04.0 Dacryoadenitis
0.677 0.323 0.000
S01 Open wound of head
0.676 0.324 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.675 0.325 0.000
T79.6 Traumatic ischaemia of muscle
0.675 0.325 0.000
S32 Fracture of lumbar spine and pelvis
0.675 0.325 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.675 0.325 0.000
Q80-Q89 Other congenital malformations
0.675 0.325 0.000
Q35-Q37 Cleft lip and cleft palate
0.675 0.325 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.675 0.325 0.000
Q00-Q07 Congenital malformations of the nervous system
0.675 0.325 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.674 0.326 0.000
F01 Vascular dementia
0.673 0.327 0.000
M77 Other enthesopathies
0.673 0.327 0.000
I08 Multiple valve diseases
0.673 0.327 0.000
S89 Other and unspecified injuries of lower leg
0.672 0.327 0.000
M79.5 Residual foreign body in soft tissue
0.672 0.328 0.000
I30 Acute pericarditis
0.671 0.329 0.000
S82.9 Fracture of lower leg, part unspecified
0.670 0.329 0.000
S82.7 Multiple fractures of lower leg
0.670 0.329 0.000
M20.3 Other deformity of hallux (acquired)
0.670 0.330 0.000
I60.8 Other subarachnoid haemorrhage
0.669 0.331 0.000
E20-E35 Disorders of other endocrine glands
0.669 0.331 0.000
T90 Sequelae of injuries of head
0.668 0.332 0.000
H36.0 Diabetic retinopathy
0.668 0.332 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.668 0.332 0.000
T98 Sequelae of other and unspecified effects of external causes
0.666 0.334 0.000
T95 Sequelae of burns, corrosions and frostbite
0.666 0.334 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.666 0.334 0.000
T91 Sequelae of injuries of neck and trunk
0.666 0.334 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.666 0.334 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.666 0.334 0.000
S50.0 Contusion of elbow
0.666 0.334 0.000
Q28 Other congenital malformations of circulatory system
0.665 0.334 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.665 0.334 0.000
S42 Fracture of shoulder and upper arm
0.664 0.336 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.663 0.337 0.000
M35.8 Other specified systemic involvement of connective tissue
0.663 0.337 0.000
M35.7 Hypermobility syndrome
0.663 0.337 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.663 0.337 0.000
M35.5 Multifocal fibrosclerosis
0.663 0.337 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.663 0.337 0.000
M35.2 Behcet's disease
0.663 0.337 0.000
M35.1 Other overlap syndromes
0.663 0.337 0.000
H20 Iridocyclitis
0.662 0.337 0.000
H25.2 Senile cataract, morgagnian type
0.662 0.338 0.000
I15 Secondary hypertension
0.662 0.338 0.000
I13 Hypertensive heart and renal disease
0.662 0.338 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.661 0.339 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.659 0.341 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.659 0.341 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.659 0.341 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.659 0.341 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.659 0.341 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.659 0.341 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.659 0.341 0.000
T36 Poisoning by systemic antibiotics
0.659 0.341 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.657 0.343 0.000
S82.5 Fracture of medial malleolus
0.655 0.344 0.000
M31.6 Other giant cell arteritis
0.654 0.345 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.653 0.347 0.000
M83 Adult osteomalacia
0.653 0.347 0.000
M82 Osteoporosis in diseases classified elsewhere
0.653 0.347 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.652 0.348 0.000
S83.2 Tear of meniscus, current
0.652 0.348 0.000
F33 Recurrent depressive disorder
0.652 0.348 0.000
M79.9 Soft tissue disorder, unspecified
0.650 0.350 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.650 0.350 0.000
M79.3 Panniculitis, unspecified
0.650 0.350 0.000
M79.2 Neuralgia and neuritis, unspecified
0.650 0.350 0.000
S51.9 Open wound of forearm, part unspecified
0.650 0.350 0.000
S80.8 Other superficial injuries of lower leg
0.650 0.350 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.650 0.350 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.649 0.351 0.000
H46 Optic neuritis
0.649 0.351 0.000
M65 Synovitis and tenosynovitis
0.648 0.352 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.648 0.352 0.000
H31 Other disorders of choroid
0.648 0.352 0.000
H30 Chorioretinal inflammation
0.648 0.352 0.000
F23 Acute and transient psychotic disorders
0.648 0.352 0.000
F28 Other nonorganic psychotic disorders
0.648 0.352 0.000
F24 Induced delusional disorder
0.648 0.352 0.000
F21 Schizotypal disorder
0.648 0.352 0.000
M79.64 Pain in limb (Hand)
0.647 0.353 0.000
I42 Cardiomyopathy
0.646 0.354 0.000
H43-H45 Disorders of vitreous body and globe
0.645 0.355 0.000
F20.0 Paranoid schizophrenia
0.645 0.355 0.000
H33.3 Retinal breaks without detachment
0.645 0.355 0.000
M24.0 Loose body in joint
0.645 0.355 0.000
Q23 Congenital malformations of aortic and mitral valves
0.645 0.355 0.000
M71 Other bursopathies
0.644 0.355 0.000
E00-E07 Disorders of thyroid gland
0.644 0.356 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.644 0.356 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.644 0.356 0.000
T86 Failure and rejection of transplanted organs and tissues
0.643 0.357 0.000
M85 Other disorders of bone density and structure
0.642 0.358 0.000
I72.0 Aneurysm of carotid artery
0.639 0.360 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.639 0.360 0.000
M79.69 Pain in limb (Site unspecified)
0.639 0.361 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.639 0.361 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.639 0.361 0.000
I34.1 Mitral (valve) prolapse
0.638 0.362 0.000
M21.0 Valgus deformity, not elsewhere classified
0.638 0.362 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.638 0.362 0.000
M79.68 Pain in limb (Other)
0.637 0.363 0.000
M79.61 Pain in limb (Shoulder region)
0.637 0.363 0.000
M25.31 Other instability of joint (Shoulder region)
0.637 0.363 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.637 0.363 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.634 0.366 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.634 0.366 0.000
E10-E14 Diabetes mellitus
0.634 0.366 0.000
M67 Other disorders of synovium and tendon
0.634 0.366 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.633 0.367 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.632 0.368 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.632 0.368 0.000
M40-M43 Deforming dorsopathies
0.631 0.369 0.000
M79.7 Fibromyalgia
0.631 0.369 0.000
I77 Other disorders of arteries and arterioles
0.631 0.369 0.000
H54.6 Unqualified visual loss, one eye
0.630 0.369 0.000
H54.5 Low vision, one eye
0.630 0.369 0.000
H54.3 Unqualified visual loss, both eyes
0.630 0.369 0.000
H54.2 Low vision, both eyes
0.630 0.369 0.000
H54.1 Blindness, one eye, low vision, other eye
0.630 0.369 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.629 0.371 0.000
M25.54 Pain in joint (Hand)
0.629 0.371 0.000
M25.37 Other instability of joint (Ankle and foot)
0.629 0.371 0.000
E70-E90 Metabolic disorders
0.627 0.373 0.000
F31.7 Bipolar affective disorder, currently in remission
0.627 0.373 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.627 0.373 0.000
S82.1 Fracture of upper end of tibia
0.626 0.374 0.000
S81.8 Open wound of other parts of lower leg
0.624 0.376 0.000
S81.7 Multiple open wounds of lower leg
0.624 0.376 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.623 0.377 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.623 0.377 0.000
H54.4 Blindness, one eye
0.623 0.377 0.000
S50.9 Superficial injury of forearm, unspecified
0.622 0.378 0.000
F20.9 Schizophrenia, unspecified
0.622 0.378 0.000
T42.4 Benzodiazepines
0.622 0.378 0.000
S82.0 Fracture of patella
0.621 0.379 0.000
F81 Specific developmental disorders of scholastic skills
0.621 0.379 0.000
S80.9 Superficial injury of lower leg, unspecified
0.621 0.379 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.621 0.379 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.621 0.379 0.000
I38 Endocarditis, valve unspecified
0.619 0.381 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.619 0.381 0.000
S52.20 Fracture of shaft of ulna (closed)
0.619 0.381 0.000
S82.3 Fracture of lower end of tibia
0.619 0.381 0.000
M79.60 Pain in limb (Multiple sites)
0.619 0.381 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.619 0.381 0.000
I07 Rheumatic tricuspid valve diseases
0.618 0.381 0.000
H57 Other disorders of eye and adnexa
0.618 0.382 0.000
I45 Other conduction disorders
0.618 0.382 0.000
Chapter VIII Diseases of the ear and mastoid process
0.618 0.382 0.000
Q27 Other congenital malformations of peripheral vascular system
0.618 0.382 0.000
Q26 Congenital malformations of great veins
0.618 0.382 0.000
Q25 Congenital malformations of great arteries
0.618 0.382 0.000
Q24 Other congenital malformations of heart
0.618 0.382 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.618 0.382 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.618 0.382 0.000
I73.9 Peripheral vascular disease, unspecified
0.618 0.382 0.000
S51.8 Open wound of other parts of forearm
0.617 0.383 0.000
S51.7 Multiple open wounds of forearm
0.617 0.383 0.000
S00.8 Superficial injury of other parts of head
0.617 0.383 0.000
I50 Heart failure
0.617 0.383 0.000
S20 Superficial injury of thorax
0.616 0.384 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.616 0.384 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.615 0.385 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.615 0.385 0.000
M25.71 Osteophyte (Shoulder region)
0.614 0.386 0.000
M72 Fibroblastic disorders
0.613 0.386 0.000
F25.9 Schizoaffective disorder, unspecified
0.613 0.387 0.000
S83.7 Injury to multiple structures of knee
0.613 0.387 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.613 0.387 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.613 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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