TreeWAS – Variant ID: rs12899147

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I20.9 Angina pectoris, unspecified	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.037	0.963
I24 Other acute ischaemic heart diseases	0.000	0.043	0.957
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.047	0.953
I20.8 Other forms of angina pectoris	0.000	0.057	0.943
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.081	0.919
I20.1 Angina pectoris with documented spasm	0.000	0.121	0.879
I71 Aortic aneurysm and dissection	0.850	0.150	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.845	0.155	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.157	0.843
I72 Other aneurysm	0.839	0.161	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.838	0.162	0.000
I72.8 Aneurysm of other specified arteries	0.807	0.193	0.000
I72.0 Aneurysm of carotid artery	0.782	0.218	0.000
I22 Subsequent myocardial infarction	0.000	0.218	0.782
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.219	0.781
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.767	0.233	0.000
I72.4 Aneurysm of artery of lower extremity	0.764	0.236	0.000
I24.1 Dressler's syndrome	0.000	0.240	0.760
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.756	0.244	0.000
I21 Acute myocardial infarction	0.000	0.252	0.748
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.257	0.743
I74 Arterial embolism and thrombosis	0.734	0.266	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.273	0.727
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.707	0.293	0.000
I25.3 Aneurysm of heart	0.000	0.293	0.707
I72.5 Aneurysm and dissection of other precerebral arteries	0.679	0.321	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.677	0.323	0.000
I25.6 Silent myocardial ischaemia	0.000	0.332	0.668
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.655	0.345	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.653	0.347	0.000
I72.3 Aneurysm of iliac artery	0.651	0.349	0.000
I78 Diseases of capillaries	0.650	0.350	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.360	0.640
I71.0 Dissection of aorta [any part]	0.637	0.363	0.000
I25.4 Coronary artery aneurysm	0.000	0.364	0.635
I72.2 Aneurysm of renal artery	0.631	0.369	0.000
I74.5 Embolism and thrombosis of iliac artery	0.610	0.390	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.609	0.391	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.609	0.391	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.602	0.398	0.000
I72.9 Aneurysm of unspecified site	0.591	0.408	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.415	0.585
I77 Other disorders of arteries and arterioles	0.584	0.416	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.577	0.423	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.576	0.424	0.000
I70 Atherosclerosis	0.557	0.443	0.000
I72.1 Aneurysm of artery of upper extremity	0.550	0.450	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.464	0.536
I78.8 Other diseases of capillaries	0.535	0.465	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.528	0.472	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.475	0.525
I22.8 Subsequent myocardial infarction of other sites	0.000	0.477	0.523
I77.9 Disorder of arteries and arterioles, unspecified	0.520	0.480	0.000
I77.8 Other specified disorders of arteries and arterioles	0.506	0.494	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.500	0.500	0.000
J43.9 Emphysema, unspecified	0.495	0.505	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.479	0.521	0.000
I70.8 Atherosclerosis of other arteries	0.470	0.530	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.531	0.469
I78.9 Disease of capillaries, unspecified	0.466	0.534	0.000
I77.2 Rupture of artery	0.463	0.537	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.541	0.459
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.541	0.459
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.541	0.459
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.541	0.459
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.541	0.459
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.541	0.459
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.541	0.459
I74.9 Embolism and thrombosis of unspecified artery	0.441	0.559	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.561	0.439
I74.8 Embolism and thrombosis of other arteries	0.436	0.564	0.000
I77.3 Arterial fibromuscular dysplasia	0.432	0.567	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.574	0.425
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.423	0.577	0.000
I77.5 Necrosis of artery	0.419	0.581	0.000
I77.4 Coeliac artery compression syndrome	0.419	0.581	0.000
I79.1 Aortitis in diseases classified elsewhere	0.414	0.586	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.414	0.586	0.000
I70.9 Generalised and unspecified atherosclerosis	0.411	0.589	0.000
I70.1 Atherosclerosis of renal artery	0.409	0.591	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.408	0.592	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.390	0.610	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.617	0.382
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.379	0.621	0.000
I21.4 Acute subendocardial myocardial infarction	0.000	0.642	0.358
I70.81 Atherosclerosis of other arteries (with gangrene)	0.337	0.663	0.000
I77.6 Arteritis, unspecified	0.335	0.665	0.000
I70.0 Atherosclerosis of aorta	0.313	0.687	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.306	0.694	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.303	0.697	0.000
I25.2 Old myocardial infarction	0.000	0.700	0.300
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.295	0.705	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.293	0.706	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.286	0.714	0.000
I77.0 Arteriovenous fistula, acquired	0.281	0.719	0.000
J43 Emphysema	0.265	0.735	0.000
I20.0 Unstable angina	0.000	0.738	0.262
I24.8 Other forms of acute ischaemic heart disease	0.000	0.746	0.253
I70.01 Atherosclerosis of aorta (with gangrene)	0.224	0.775	0.000
I73 Other peripheral vascular diseases	0.220	0.780	0.000
J43.2 Centrilobular emphysema	0.216	0.784	0.000
J43.8 Other emphysema	0.193	0.807	0.000
J43.1 Panlobular emphysema	0.190	0.810	0.000
J43.0 MacLeod's syndrome	0.190	0.810	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.177	0.823	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.171	0.829	0.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.854	0.146
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.143	0.857	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.138	0.862	0.000
I73.8 Other specified peripheral vascular diseases	0.129	0.871	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.002	0.872	0.126
I78.1 Naevus, nonneoplastic	0.118	0.882	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.108	0.892	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.894	0.106
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.899	0.101
I73.9 Peripheral vascular disease, unspecified	0.098	0.902	0.000
H35.3 Degeneration of macula and posterior pole	0.070	0.930	0.000
I77.1 Stricture of artery	0.064	0.936	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.942	0.058
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.954	0.046
Z95.3 Presence of xenogenic heart valve	0.000	0.966	0.034
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.970	0.030
I73.0 Raynaud's syndrome	0.023	0.977	0.000
M06.9 Rheumatoid arthritis, unspecified	0.016	0.984	0.000
C67.1 Dome of bladder	0.015	0.985	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.014	0.986	0.000
M06.0 Seronegative rheumatoid arthritis	0.014	0.986	0.000
Chapter IX Diseases of the circulatory system	0.013	0.987	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.013	0.987	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.013	0.987	0.000
M06 Other rheumatoid arthritis	0.013	0.987	0.000
C67 Malignant neoplasm of bladder	0.012	0.988	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.012	0.988	0.000
R45.8 Other symptoms and signs involving emotional state	0.000	0.988	0.012
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.012	0.988	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.012	0.988	0.000
C67.2 Lateral wall of bladder	0.012	0.988	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.012	0.988	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.011	0.989	0.000
I00-I02 Acute rheumatic fever	0.011	0.989	0.000
C67.4 Posterior wall of bladder	0.011	0.989	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.011	0.989	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.989	0.011
I05-I09 Chronic rheumatic heart diseases	0.011	0.989	0.000
C67.0 Trigone of bladder	0.011	0.989	0.000
I06 Rheumatic aortic valve diseases	0.011	0.989	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.011	0.989	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.010	0.989	0.000
I05.0 Mitral stenosis	0.010	0.990	0.000
I05 Rheumatic mitral valve diseases	0.010	0.990	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.010	0.990	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.010	0.990	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.010	0.990	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.010	0.990	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.010	0.990	0.000
C67.6 Ureteric orifice	0.010	0.990	0.000
I00 Rheumatic fever without mention of heart involvement	0.010	0.990	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.010	0.990	0.000
M06.8 Other specified rheumatoid arthritis	0.010	0.990	0.000
I06.0 Rheumatic aortic stenosis	0.010	0.990	0.000
M06.3 Rheumatoid nodule	0.010	0.990	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.009	0.990	0.000
I06.1 Rheumatic aortic insufficiency	0.009	0.991	0.000
M06.2 Rheumatoid bursitis	0.009	0.991	0.000
M06.1 Adult-onset Still's disease	0.009	0.991	0.000
C67.3 Anterior wall of bladder	0.009	0.991	0.000
C67.7 Urachus	0.009	0.991	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.009	0.991	0.000
S62.61 Fracture of other finger (open)	0.009	0.991	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.008	0.991	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.008	0.991	0.000
I98.0 Cardiovascular syphilis	0.008	0.991	0.000
L03.3 Cellulitis of trunk	0.000	0.991	0.009
I02 Rheumatic chorea	0.008	0.992	0.000
I01 Rheumatic fever with heart involvement	0.008	0.992	0.000
C67.8 Overlapping lesion of bladder	0.008	0.992	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.008	0.992	0.000
I05.1 Rheumatic mitral insufficiency	0.008	0.992	0.000
I06.8 Other rheumatic aortic valve diseases	0.008	0.992	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.008	0.992	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.008	0.992	0.000
I99 Other and unspecified disorders of circulatory system	0.008	0.992	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.008	0.992	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.008	0.992	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.992	0.008
I09 Other rheumatic heart diseases	0.008	0.992	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.008	0.992	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.007	0.992	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.007	0.992	0.000
I05.8 Other mitral valve diseases	0.007	0.992	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.007	0.993	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.007	0.993	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.007	0.993	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.007	0.993	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.007	0.993	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.007	0.993	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.007	0.993	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.007	0.993	0.000
K62.8 Other specified diseases of anus and rectum	0.007	0.993	0.000
H35 Other retinal disorders	0.007	0.993	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.007	0.993	0.000
M06.38 Rheumatoid nodule (Other)	0.007	0.993	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.007	0.993	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.007	0.993	0.000
M06.33 Rheumatoid nodule (Forearm)	0.007	0.993	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.007	0.993	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.993	0.007
M06.98 Rheumatoid arthritis, unspecified (Other)	0.007	0.993	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.007	0.993	0.000
M06.18 Adult-onset Still's disease (Other)	0.007	0.993	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.007	0.993	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.007	0.993	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.007	0.993	0.000
M06.14 Adult-onset Still's disease (Hand)	0.007	0.993	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.007	0.993	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.007	0.993	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.007	0.993	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.007	0.993	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.007	0.993	0.000
M06.28 Rheumatoid bursitis (Other)	0.007	0.993	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.007	0.993	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.007	0.993	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.007	0.993	0.000
M06.24 Rheumatoid bursitis (Hand)	0.007	0.993	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.007	0.993	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.007	0.993	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.007	0.993	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.007	0.993	0.000
H35.2 Other proliferative retinopathy	0.007	0.993	0.000
I05.2 Mitral stenosis with insufficiency	0.007	0.993	0.000
H35.9 Retinal disorder, unspecified	0.007	0.993	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.006	0.993	0.000
I28 Other diseases of pulmonary vessels	0.006	0.993	0.000
M06.4 Inflammatory polyarthropathy	0.006	0.993	0.000
I07 Rheumatic tricuspid valve diseases	0.006	0.993	0.000
C67.5 Bladder neck	0.006	0.994	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.994	0.006
I01.9 Acute rheumatic heart disease, unspecified	0.006	0.994	0.000
I01.8 Other acute rheumatic heart disease	0.006	0.994	0.000
I01.2 Acute rheumatic myocarditis	0.006	0.994	0.000
I01.1 Acute rheumatic endocarditis	0.006	0.994	0.000
I01.0 Acute rheumatic pericarditis	0.006	0.994	0.000
I02.9 Rheumatic chorea without heart involvement	0.006	0.994	0.000
I02.0 Rheumatic chorea with heart involvement	0.006	0.994	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.006	0.994	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.006	0.994	0.000
I05.9 Mitral valve disease, unspecified	0.006	0.994	0.000
M06.34 Rheumatoid nodule (Hand)	0.006	0.994	0.000
I09.8 Other specified rheumatic heart diseases	0.006	0.994	0.000
I09.2 Chronic rheumatic pericarditis	0.006	0.994	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.006	0.994	0.000
I09.0 Rheumatic myocarditis	0.006	0.994	0.000
I28.8 Other specified diseases of pulmonary vessels	0.006	0.994	0.000
H35.1 Retinopathy of prematurity	0.005	0.995	0.000
N81.9 Female genital prolapse, unspecified	0.000	0.995	0.005
Z33 Pregnant state, incidental	0.005	0.995	0.000
I09.9 Rheumatic heart disease, unspecified	0.005	0.995	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.005	0.995	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.005	0.995	0.000
I28.1 Aneurysm of pulmonary artery	0.005	0.995	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.005	0.995	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.005	0.995	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.005	0.995	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.005	0.995	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.005	0.995	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.005	0.995	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.005	0.995	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.005	0.995	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.005	0.995	0.000
I07.9 Tricuspid valve disease, unspecified	0.005	0.995	0.000
I07.8 Other tricuspid valve diseases	0.005	0.995	0.000
I07.2 Tricuspid stenosis with insufficiency	0.005	0.995	0.000
I07.0 Tricuspid stenosis	0.005	0.995	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.005	0.995	0.000
I97.0 Postcardiotomy syndrome	0.005	0.995	0.000
I42.0 Dilated cardiomyopathy	0.005	0.995	0.000
H35.6 Retinal haemorrhage	0.005	0.995	0.000
W19.4 Street and highway	0.004	0.996	0.000
H35.8 Other specified retinal disorders	0.004	0.996	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.004	0.996	0.000
L60.8 Other nail disorders	0.004	0.996	0.000
F81 Specific developmental disorders of scholastic skills	0.000	0.996	0.004
I26 Pulmonary embolism	0.004	0.996	0.000
I27 Other pulmonary heart diseases	0.004	0.996	0.000
S32.50 Fracture of pubis (closed)	0.004	0.996	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.004	0.996	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.004	0.996	0.000
R45.2 Unhappiness	0.000	0.996	0.004
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.003	0.996	0.000
R45 Symptoms and signs involving emotional state	0.000	0.996	0.004
H35.7 Separation of retinal layers	0.003	0.996	0.000
C67.9 Bladder, unspecified	0.004	0.996	0.000
H35.0 Background retinopathy and retinal vascular changes	0.003	0.996	0.000
I97.1 Other functional disturbances following cardiac surgery	0.003	0.997	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.003	0.997	0.000
I27.9 Pulmonary heart disease, unspecified	0.003	0.997	0.000
F40.2 Specific (isolated) phobias	0.003	0.997	0.000
F40.9 Phobic anxiety disorder, unspecified	0.003	0.997	0.000
I10-I15 Hypertensive diseases	0.003	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.003	0.997	0.000
I07.1 Tricuspid insufficiency	0.003	0.997	0.000
F81.8 Other developmental disorders of scholastic skills	0.000	0.997	0.003
F81.3 Mixed disorder of scholastic skills	0.000	0.997	0.003
F81.2 Specific disorder of arithmetical skills	0.000	0.997	0.003
F81.1 Specific spelling disorder	0.000	0.997	0.003
F81.0 Specific reading disorder	0.000	0.997	0.003
S06.30 Focal brain injury (without open intracranial wound)	0.003	0.997	0.000
C64-C68 Malignant neoplasms of urinary tract	0.003	0.997	0.000
H35.5 Hereditary retinal dystrophy	0.003	0.997	0.000
K55.2 Angiodysplasia of colon	0.003	0.997	0.000
Z99.2 Dependence on renal dialysis	0.003	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.003	0.997	0.000
C66 Malignant neoplasm of ureter	0.003	0.997	0.000
Z72.1 Alcohol use	0.003	0.997	0.000
R45.6 Physical violence	0.000	0.997	0.003
R45.0 Nervousness	0.000	0.997	0.003
I82.8 Embolism and thrombosis of other specified veins	0.000	0.997	0.003
C68 Malignant neoplasm of other and unspecified urinary organs	0.003	0.997	0.000
R10.2 Pelvic and perineal pain	0.000	0.997	0.003
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.997	0.000
N88.2 Stricture and stenosis of cervix uteri	0.000	0.997	0.003
R45.3 Demoralisation and apathy	0.000	0.997	0.003
I27.8 Other specified pulmonary heart diseases	0.003	0.997	0.000
I15 Secondary hypertension	0.003	0.997	0.000
I13 Hypertensive heart and renal disease	0.003	0.997	0.000
I15.9 Seconday hypertension, unspecified	0.003	0.997	0.000
F40 Phobic anxiety disorders	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.997	0.003
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.997	0.003
C68.0 Urethra	0.003	0.997	0.000
R45.4 Irritability and anger	0.000	0.997	0.003
R45.5 Hostility	0.000	0.997	0.002
C68.9 Urinary organ, unspecified	0.002	0.997	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.997	0.003
I13.1 Hypertensive heart and renal disease with renal failure	0.002	0.997	0.000
L03.9 Cellulitis, unspecified	0.000	0.997	0.003
T63.4 Venom of other arthropods	0.000	0.997	0.002
M50.1 Cervical disk disorder with radiculopathy	0.000	0.998	0.002
R45.7 State of emotional shock and stress, unspecified	0.000	0.998	0.002
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
N41.0 Acute prostatitis	0.000	0.998	0.002
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.998	0.002
C68.8 Overlapping lesion of urinary organs	0.002	0.998	0.000
C68.1 Paraurethral glands	0.002	0.998	0.000
F40.8 Other phobic anxiety disorders	0.002	0.998	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
I15.8 Other secondary hypertension	0.002	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.002	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.002	0.998	0.000
L03 Cellulitis	0.000	0.998	0.002
I15.2 Hypertension secondary to endocrine disorders	0.002	0.998	0.000
I11 Hypertensive heart disease	0.002	0.998	0.000
F40.1 Social phobias	0.002	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.998	0.002
I15.0 Renovascular hypertension	0.002	0.998	0.000
Z82.1 Family history of blindness and visual loss	0.000	0.998	0.002
X23.0 Home	0.000	0.998	0.002
F40.0 Agoraphobia	0.002	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
H35.4 Peripheral retinal degeneration	0.002	0.998	0.000
J40-J47 Chronic lower respiratory diseases	0.002	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
M77.57 Other enthesopathy of foot-Ankle/Foot	0.000	0.998	0.002
G80.1 Spastic diplegia	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
M45 Ankylosing spondylitis	0.000	0.998	0.002
I15.1 Hypertension secondary to other renal disorders	0.002	0.998	0.000
M22.4 Chondromalacia patellae	0.000	0.998	0.002
Z82.2 Family history of deafness and hearing loss	0.000	0.998	0.002
I60-I69 Cerebrovascular diseases	0.002	0.998	0.000
I67 Other cerebrovascular diseases	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.002	0.998	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.998	0.002
Z95.2 Presence of prosthetic heart valve	0.000	0.998	0.002
L03.0 Cellulitis of finger and toe	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
I67.9 Cerebrovascular disease, unspecified	0.002	0.998	0.000
S32.5 Fracture of pubis	0.002	0.998	0.000
H43.8 Other disorders of vitreous body	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
Z12.5 Special screening examination for neoplasm of prostate	0.002	0.998	0.000
L03.2 Cellulitis of face	0.000	0.998	0.002
F52.2 Failure of genital response	0.002	0.998	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.002	0.998	0.000
Y83.0 Surgical operation with transplant of whole organ	0.002	0.998	0.000
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
T82.3 Mechanical complication of other vascular grafts	0.002	0.998	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.998	0.002
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.002	0.998	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.002	0.998	0.000
H18.6 Keratoconus	0.000	0.998	0.002
I66.0 Occlusion and stenosis of middle cerebral artery	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.002	0.998	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.998	0.002
F80-F89 Disorders of psychological development	0.000	0.998	0.002
C34.9 Bronchus or lung, unspecified	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.002	0.998	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.998	0.002
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.998	0.002
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.998	0.002
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.998	0.002
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.998	0.002
F84 Pervasive developmental disorders	0.000	0.998	0.002
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.002	0.998	0.000
I67.5 Moyamoya disease	0.002	0.998	0.000
I67.4 Hypertensive encephalopathy	0.002	0.998	0.000
I67.3 Progressive vascular leukoencephalopathy	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.998	0.002
Z49.0 Preparatory care for dialysis	0.002	0.998	0.000
J41 Simple and mucopurulent chronic bronchitis	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.002	0.998	0.000
S62.6 Fracture of other finger	0.002	0.998	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.002	0.998	0.000
N05.9 Unspecified	0.002	0.998	0.000
S32.51 Fracture of pubis (open)	0.002	0.998	0.000
G80.2 Infantile hemiplegia	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.001	0.998	0.000
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
F84.5 Asperger's syndrome	0.000	0.998	0.002
H20.0 Acute and subacute iridocyclitis	0.000	0.998	0.002
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.998	0.002
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.002	0.998	0.000
K55.8 Other vascular disorders of intestine	0.002	0.998	0.000
N85.2 Hypertrophy of uterus	0.000	0.998	0.002
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
I68.0 Cerebral amyloid angiopathy	0.002	0.998	0.000
J44 Other chronic obstructive pulmonary disease	0.002	0.998	0.000
F84.0 Childhood autism	0.000	0.998	0.001
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.998	0.002
G63.2 Diabetic polyneuropathy	0.002	0.998	0.000
I95.1 Orthostatic hypotension	0.000	0.998	0.002
I66.8 Occlusion and stenosis of other cerebral artery	0.001	0.998	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.001	0.998	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.001	0.998	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.001	0.998	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.001	0.998	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
I87.8 Other specified disorders of veins	0.000	0.998	0.002
G80.4 Ataxic cerebral palsy	0.001	0.998	0.000
G80.3 Dyskinetic cerebral palsy	0.001	0.998	0.000
G80.0 Spastic cerebral palsy	0.001	0.998	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.001	0.998	0.000
F89 Unspecified disorder of psychological development	0.000	0.998	0.001
F88 Other disorders of psychological development	0.000	0.998	0.001
F83 Mixed specific developmental disorders	0.000	0.998	0.001
F82 Specific developmental disorder of motor function	0.000	0.998	0.001
H02.5 Other disorders affecting eyelid function	0.000	0.998	0.002
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.998	0.001
V89.9 Person injured in unspecified vehicle accident	0.000	0.998	0.002
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
B08.1 Molluscum contagiosum	0.002	0.998	0.000
F84.9 Pervasive developmental disorder, unspecified	0.000	0.998	0.001
F84.8 Other pervasive developmental disorders	0.000	0.998	0.001
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.000	0.998	0.001
F84.3 Other childhood disintegrative disorder	0.000	0.998	0.001
F84.2 Rett's syndrome	0.000	0.998	0.001
F84.1 Atypical autism	0.000	0.998	0.001
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.001	0.998	0.000
J41.1 Mucopurulent chronic bronchitis	0.001	0.998	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.998	0.001
S72.00 Fracture of neck of femur (closed)	0.002	0.998	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
N81.3 Complete uterovaginal prolapse	0.000	0.998	0.002
C71.2 Temporal lobe	0.000	0.998	0.002
H18.5 Hereditary corneal dystrophies	0.000	0.998	0.001
I60.8 Other subarachnoid haemorrhage	0.001	0.998	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.001	0.998	0.000
J41.0 Simple chronic bronchitis	0.001	0.998	0.000
M20.5 Other deformities of toe(s) (acquired)	0.002	0.998	0.000
Z52.4 Kidney donor	0.001	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.999	0.000
N05.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.001	0.999	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations