TreeWAS – Variant ID: rs6683071

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.001	0.999
I21 Acute myocardial infarction	0.000	0.002	0.998
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.017	0.983
I50.1 Left ventricular failure	0.000	0.025	0.975
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.029	0.971
I22 Subsequent myocardial infarction	0.000	0.043	0.957
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.053	0.947
I25.3 Aneurysm of heart	0.000	0.071	0.929
I21.4 Acute subendocardial myocardial infarction	0.000	0.078	0.922
I50 Heart failure	0.000	0.090	0.910
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.098	0.902
I22.8 Subsequent myocardial infarction of other sites	0.000	0.118	0.882
I50.9 Heart failure, unspecified	0.000	0.119	0.881
I24 Other acute ischaemic heart diseases	0.000	0.131	0.869
I25.5 Ischaemic cardiomyopathy	0.000	0.180	0.820
I24.8 Other forms of acute ischaemic heart disease	0.000	0.182	0.818
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.207	0.793
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.218	0.782
Z95.1 Presence of aortocoronary bypass graft	0.000	0.224	0.776
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.281	0.719
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.284	0.716
O00-O08 Pregnancy with abortive outcome	0.707	0.293	0.000
O04 Medical abortion	0.700	0.300	0.000
O03 Spontaneous abortion	0.700	0.300	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.301	0.699
Chapter XV Pregnancy, childbirth and the puerperium	0.698	0.302	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.305	0.695
O26 Maternal care for other conditions predominantly related to pregnancy	0.692	0.308	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.692	0.308	0.000
O03.4 Incomplete, without complication	0.691	0.309	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.309	0.691
O26.8 Other specified pregnancy-related conditions	0.691	0.309	0.000
O04.9 Complete or unspecified, without complication	0.676	0.324	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.326	0.674
O80-O84 Delivery	0.665	0.335	0.000
O85-O92 Complications predominantly related to the puerperium	0.653	0.347	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.648	0.352	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.648	0.352	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.353	0.647
I50.0 Congestive heart failure	0.000	0.354	0.646
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.382	0.618
I21.9 Acute myocardial infarction, unspecified	0.000	0.388	0.612
O86 Other puerperal infections	0.603	0.397	0.000
O80 Single spontaneous delivery	0.595	0.405	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.589	0.411	0.000
I24.1 Dressler's syndrome	0.000	0.416	0.584
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.417	0.583
O80.0 Spontaneous vertex delivery	0.570	0.430	0.000
O24 Diabetes mellitus in pregnancy	0.569	0.431	0.000
O82 Single delivery by Caesarean section	0.567	0.433	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.566	0.434	0.000
O03.3 Incomplete, with other and unspecified complications	0.559	0.441	0.000
O47 False labour	0.554	0.446	0.000
O86.0 Infection of obstetric surgical wound	0.549	0.451	0.000
O81 Single delivery by forceps and vacuum extractor	0.546	0.454	0.000
O40 Polyhydramnios	0.545	0.455	0.000
O47.0 False labour before 37 completed weeks of gestation	0.540	0.460	0.000
O04.4 Incomplete, without complication	0.539	0.461	0.000
O87 Venous complications in the puerperium	0.536	0.463	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.530	0.470	0.000
O03.9 Complete or unspecified, without complication	0.520	0.480	0.000
O22 Venous complications in pregnancy	0.513	0.487	0.000
I30-I52 Other forms of heart disease	0.000	0.492	0.508
O34 Maternal care for known or suspected abnormality of pelvic organs	0.507	0.493	0.000
O23 Infections of genito-urinary tract in pregnancy	0.507	0.493	0.000
O07 Failed attempted abortion	0.507	0.493	0.000
O06 Unspecified abortion	0.507	0.493	0.000
O05 Other abortion	0.507	0.493	0.000
O01 Hydatidiform mole	0.507	0.493	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.502	0.498	0.000
O04.7 Complete or unspecified, complicated by embolism	0.502	0.498	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.502	0.498	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.502	0.498	0.000
O04.3 Incomplete, with other and unspecified complications	0.502	0.498	0.000
O04.2 Incomplete, complicated by embolism	0.502	0.498	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.502	0.498	0.000
O03.7 Complete or unspecified, complicated by embolism	0.502	0.498	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.502	0.498	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.502	0.498	0.000
O03.2 Incomplete, complicated by embolism	0.502	0.498	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.502	0.498	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.501	0.499	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.496	0.503	0.000
O26.5 Maternal hypotension syndrome	0.496	0.503	0.000
O26.4 Herpes gestationis	0.496	0.503	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.496	0.503	0.000
O26.1 Low weight gain in pregnancy	0.496	0.503	0.000
O29 Complications of anaesthesia during pregnancy	0.496	0.504	0.000
O25 Malnutrition in pregnancy	0.496	0.504	0.000
O82.9 Delivery by Caesarean section, unspecified	0.496	0.504	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.505	0.495
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.505	0.495
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.505	0.495
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.505	0.495
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.505	0.495
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.505	0.495
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.505	0.495
Chapter IX Diseases of the circulatory system	0.000	0.505	0.495
O86.4 Pyrexia of unknown origin following delivery	0.492	0.508	0.000
O82.0 Delivery by elective Caesarean section	0.492	0.508	0.000
O26.0 Excessive weight gain in pregnancy	0.489	0.511	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.514	0.486
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.479	0.520	0.000
O84 Multiple delivery	0.477	0.523	0.000
O83 Other assisted single delivery	0.477	0.523	0.000
O21 Excessive vomiting in pregnancy	0.473	0.527	0.000
O90 Complications of the puerperium, not elsewhere classified	0.471	0.529	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.530	0.470
I23.8 Other current complications following acute myocardial infarction	0.000	0.530	0.469
I05-I09 Chronic rheumatic heart diseases	0.000	0.531	0.469
O91 Infections of breast associated with childbirth	0.468	0.532	0.000
O89 Complications of anaesthesia during the puerperium	0.468	0.532	0.000
O88 Obstetric embolism	0.468	0.532	0.000
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.466	0.534	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.534	0.466
O26.2 Pregnancy care of habitual aborter	0.463	0.537	0.000
O33 Maternal care for known or suspected disproportion	0.461	0.539	0.000
O34.1 Maternal care for tumour of corpus uteri	0.459	0.541	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.543	0.457
I51 Complications and ill-defined descriptions of heart disease	0.000	0.543	0.457
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.457	0.543	0.000
O81.4 Vacuum extractor delivery	0.453	0.547	0.000
O87.2 Haemorrhoids in the puerperium	0.453	0.547	0.000
I33 Acute and subacute endocarditis	0.000	0.561	0.439
O30 Multiple gestation	0.439	0.561	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.434	0.566	0.000
O86.8 Other specified puerperal infections	0.432	0.567	0.000
O86.3 Other genito-urinary tract infections following delivery	0.432	0.567	0.000
O86.1 Other infection of genital tract following delivery	0.432	0.567	0.000
O81.3 Other and unspecified forceps delivery	0.432	0.568	0.000
O28 Abnormal findings on antenatal screening of mother	0.430	0.570	0.000
O36 Maternal care for other known or suspected foetal problems	0.430	0.570	0.000
O86.2 Urinary tract infection following delivery	0.427	0.573	0.000
O80.1 Spontaneous breech delivery	0.427	0.573	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.576	0.424
O31 Complications specific to multiple gestation	0.423	0.577	0.000
I37 Pulmonary valve disorders	0.000	0.577	0.423
O85 Puerperal sepsis	0.422	0.578	0.000
I08 Multiple valve diseases	0.000	0.581	0.419
O24.4 Diabetes mellitus arising in pregnancy	0.418	0.582	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.411	0.589	0.000
I25.4 Coronary artery aneurysm	0.001	0.590	0.409
O45 Premature separation of placenta [abruptio placentae]	0.409	0.591	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.408	0.592	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.408	0.592	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.408	0.592	0.000
O82.8 Other single delivery by Caesarean section	0.406	0.594	0.000
O82.2 Delivery by Caesarean hysterectomy	0.406	0.594	0.000
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.406	0.594	0.000
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.406	0.594	0.000
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.406	0.594	0.000
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.406	0.594	0.000
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.406	0.594	0.000
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.406	0.594	0.000
O08.3 Shock following abortion and ectopic and molar pregnancy	0.406	0.594	0.000
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.406	0.594	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.406	0.594	0.000
I05 Rheumatic mitral valve diseases	0.000	0.596	0.404
O80.8 Other single spontaneous delivery	0.404	0.596	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.602	0.398
O81.5 Delivery by combination of forceps and vacuum extractor	0.391	0.609	0.000
O81.2 Mid-cavity forceps with rotation	0.391	0.609	0.000
O81.1 Mid-cavity forceps delivery	0.391	0.609	0.000
O92.1 Cracked nipple associated with childbirth	0.391	0.609	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.610	0.390
O22.0 Varicose veins of lower extremity in pregnancy	0.389	0.611	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.611	0.389
O94-O99 Other obstetric conditions, not elsewhere classified	0.388	0.612	0.000
O34.4 Maternal care for other abnormalities of cervix	0.388	0.612	0.000
O43 Placental disorders	0.388	0.612	0.000
O34.3 Maternal care for cervical incompetence	0.387	0.613	0.000
I51.6 Cardiovascular disease, unspecified	0.000	0.614	0.386
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.385	0.615	0.000
O87.9 Venous complication in the puerperium, unspecified	0.385	0.615	0.000
O87.8 Other venous complications in the puerperium	0.385	0.615	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.385	0.615	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.385	0.615	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.385	0.615	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.385	0.615	0.000
O48 Prolonged pregnancy	0.385	0.615	0.000
I09 Other rheumatic heart diseases	0.000	0.618	0.381
I30 Acute pericarditis	0.000	0.619	0.381
I51.9 Heart disease, unspecified	0.000	0.620	0.380
I45 Other conduction disorders	0.000	0.621	0.379
O23.4 Unspecified infection of urinary tract in pregnancy	0.375	0.625	0.000
I51.0 Cardiac septal defect, acquired	0.000	0.626	0.374
O47.9 False labour, unspecified	0.373	0.627	0.000
O90.0 Disruption of Caesarean section wound	0.371	0.629	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.631	0.369
O22.9 Venous complication in pregnancy, unspecified	0.368	0.632	0.000
O22.8 Other venous complications in pregnancy	0.368	0.632	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.368	0.632	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.368	0.632	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.368	0.632	0.000
O22.1 Genital varices in pregnancy	0.368	0.632	0.000
I52 Other heart disorders in diseases classified elsewhere	0.000	0.636	0.364
I48 Atrial fibrillation and flutter	0.000	0.636	0.364
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.636	0.364
I41 Myocarditis in diseases classified elsewhere	0.000	0.636	0.364
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.636	0.364
I32 Pericarditis in diseases classified elsewhere	0.000	0.636	0.364
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.364	0.636	0.000
O34.6 Maternal care for abnormality of vagina	0.364	0.636	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.364	0.636	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.364	0.636	0.000
O23.2 Infections of urethra in pregnancy	0.364	0.636	0.000
O23.1 Infections of bladder in pregnancy	0.364	0.636	0.000
O23.0 Infections of kidney in pregnancy	0.364	0.636	0.000
O01.9 Hydatidiform mole, unspecified	0.363	0.637	0.000
O01.1 Incomplete and partial hydatidiform mole	0.363	0.637	0.000
O01.0 Classical hydatidiform mole	0.363	0.637	0.000
O05.9 Complete or unspecified, without complication	0.363	0.637	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.363	0.637	0.000
O05.7 Complete or unspecified, complicated by embolism	0.363	0.637	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.363	0.637	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.363	0.637	0.000
O05.4 Incomplete, without complication	0.363	0.637	0.000
O05.3 Incomplete, with other and unspecified complications	0.363	0.637	0.000
O05.2 Incomplete, complicated by embolism	0.363	0.637	0.000
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.363	0.637	0.000
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.363	0.637	0.000
O06.9 Complete or unspecified, without complication	0.363	0.637	0.000
O06.8 Complete or unspecified, with other and unspecified complications	0.363	0.637	0.000
O06.7 Complete or unspecified, complicated by embolism	0.363	0.637	0.000
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.363	0.637	0.000
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.363	0.637	0.000
O06.4 Incomplete, without complication	0.363	0.637	0.000
O06.3 Incomplete, with other and unspecified complications	0.363	0.637	0.000
O06.2 Incomplete, complicated by embolism	0.363	0.637	0.000
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.363	0.637	0.000
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.363	0.637	0.000
O07.9 Other and unspecified failed attempted abortion, without complication	0.363	0.637	0.000
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.363	0.637	0.000
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.363	0.637	0.000
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.363	0.637	0.000
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.363	0.637	0.000
O07.4 Failed medical abortion, without complication	0.363	0.637	0.000
O07.3 Failed medical abortion, with other and unspecified complications	0.363	0.637	0.000
O07.2 Failed medical abortion, complicated by embolism	0.363	0.637	0.000
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.363	0.637	0.000
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.363	0.637	0.000
O22.4 Haemorrhoids in pregnancy	0.363	0.637	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.638	0.362
O21.0 Mild hyperemesis gravidarum	0.361	0.639	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.361	0.639	0.000
O44 Placenta praevia	0.360	0.640	0.000
O92.7 Other and unspecified disorders of lactation	0.359	0.640	0.000
O92.6 Galactorrhoea	0.359	0.640	0.000
O92.5 Suppressed lactation	0.359	0.640	0.000
O92.4 Hypogalactia	0.359	0.640	0.000
O92.3 Agalactia	0.359	0.640	0.000
O92.0 Retracted nipple associated with childbirth	0.359	0.640	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.359	0.641	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.642	0.358
O41 Other disorders of amniotic fluid and membranes	0.358	0.642	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.356	0.644	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.356	0.644	0.000
O29.6 Failed or difficult intubation during pregnancy	0.356	0.644	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.356	0.644	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.356	0.644	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.356	0.644	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.356	0.644	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.356	0.644	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.356	0.644	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.645	0.355
I08.0 Disorders of both mitral and aortic valves	0.000	0.645	0.355
O33.5 Maternal care for disproportion due to unusually large foetus	0.354	0.646	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.352	0.648	0.000
O34.0 Maternal care for congenital malformation of uterus	0.352	0.648	0.000
O81.0 Low forceps delivery	0.351	0.648	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.351	0.649	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.350	0.650	0.000
O90.2 Haematoma of obstetric wound	0.349	0.651	0.000
O33.9 Maternal care for disproportion, unspecified	0.349	0.651	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.651	0.349
O02 Other abnormal products of conception	0.348	0.652	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.347	0.653	0.000
I46 Cardiac arrest	0.000	0.656	0.344
O83.9 Assisted single delivery, unspecified	0.342	0.658	0.000
O83.8 Other specified assisted single delivery	0.342	0.658	0.000
O83.4 Destructive operation for delivery	0.342	0.658	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.342	0.658	0.000
O83.2 Other manipulation-assisted delivery	0.342	0.658	0.000
O83.1 Other assisted breech delivery	0.342	0.658	0.000
O83.0 Breech extraction	0.342	0.658	0.000
O84.9 Multiple delivery, unspecified	0.342	0.658	0.000
O84.8 Other multiple delivery	0.342	0.658	0.000
O84.2 Multiple delivery, all by Caesarean section	0.342	0.658	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.342	0.658	0.000
O84.0 Multiple delivery, all spontaneous	0.342	0.658	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.660	0.339
O23.5 Infections of the genital tract in pregnancy	0.339	0.661	0.000
O21.8 Other vomiting complicating pregnancy	0.339	0.661	0.000
O90.1 Disruption of perineal obstetric wound	0.339	0.661	0.000
O90.5 Postpartum thyroiditis	0.338	0.662	0.000
O90.4 Postpartum acute renal failure	0.338	0.662	0.000
O90.3 Cardiomyopathy in the puerperium	0.338	0.662	0.000
O88.8 Other obstetric embolism	0.336	0.664	0.000
O88.3 Obstetric pyaemic and septic embolism	0.336	0.664	0.000
O88.2 Obstetric blood-clot embolism	0.336	0.664	0.000
O88.1 Amniotic fluid embolism	0.336	0.664	0.000
O88.0 Obstetric air embolism	0.336	0.664	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.336	0.664	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.336	0.664	0.000
O89.6 Failed or difficult intubation during the puerperium	0.336	0.664	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.336	0.664	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.336	0.664	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.336	0.664	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.336	0.664	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.336	0.664	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.336	0.664	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.336	0.664	0.000
O91.1 Abscess of breast associated with childbirth	0.336	0.664	0.000
O91.0 Infection of nipple associated with childbirth	0.336	0.664	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.664	0.335
I06 Rheumatic aortic valve diseases	0.000	0.666	0.334
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.331	0.668	0.000
O36.9 Maternal care for foetal problem, unspecified	0.331	0.669	0.000
O30.0 Twin pregnancy	0.331	0.669	0.000
O33.8 Maternal care for disproportion of other origin	0.330	0.669	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.330	0.669	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.330	0.669	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.330	0.669	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.330	0.669	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.330	0.669	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.330	0.669	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.330	0.669	0.000
O21.2 Late vomiting of pregnancy	0.330	0.670	0.000
O26.9 Pregnancy-related condition, unspecified	0.329	0.671	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.328	0.672	0.000
I51.5 Myocardial degeneration	0.000	0.672	0.328
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.672	0.328
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.324	0.676	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.324	0.676	0.000
I51.4 Myocarditis, unspecified	0.000	0.677	0.323
I45.6 Preexcitation syndrome	0.000	0.678	0.322
I45.9 Conduction disorder, unspecified	0.000	0.679	0.321
I00-I02 Acute rheumatic fever	0.000	0.680	0.320
I09.9 Rheumatic heart disease, unspecified	0.000	0.681	0.319
I51.8 Other ill-defined heart diseases	0.000	0.681	0.319
I08.8 Other multiple valve diseases	0.000	0.684	0.316
O34.2 Maternal care due to uterine scar from previous surgery	0.315	0.685	0.000
I33.9 Acute endocarditis, unspecified	0.000	0.685	0.315
O30.9 Multiple gestation, unspecified	0.315	0.685	0.000
O30.8 Other multiple gestation	0.315	0.685	0.000
O30.2 Quadruplet pregnancy	0.315	0.685	0.000
O30.1 Triplet pregnancy	0.315	0.685	0.000
I40 Acute myocarditis	0.000	0.686	0.314
I07 Rheumatic tricuspid valve diseases	0.000	0.686	0.314
O43.0 Placental transfusion syndromes	0.313	0.687	0.000
O36.4 Maternal care for intra-uterine death	0.311	0.689	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.308	0.691	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.308	0.691	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.308	0.691	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.308	0.691	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.308	0.691	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.308	0.691	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.308	0.691	0.000
O36.2 Maternal care for hydrops foetalis	0.308	0.691	0.000
O36.1 Maternal care for other isoimmunisation	0.308	0.691	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.692	0.308
I36 Nonrheumatic tricuspid valve disorders	0.000	0.695	0.305
I05.0 Mitral stenosis	0.000	0.696	0.304
O80.9 Single spontaneous delivery, unspecified	0.303	0.697	0.000
O31.8 Other complications specific to multiple gestation	0.303	0.697	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.303	0.697	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.303	0.697	0.000
O31.0 Papyraceous foetus	0.303	0.697	0.000
I37.9 Pulmonary valve disorder, unspecified	0.000	0.697	0.303
I37.8 Other pulmonary valve disorders	0.000	0.697	0.303
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.697	0.303
I37.0 Pulmonary valve stenosis	0.000	0.697	0.303
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.697	0.303
O00 Ectopic pregnancy	0.302	0.697	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.701	0.299
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.299	0.701	0.000
O90.9 Complication of the puerperium, unspecified	0.295	0.704	0.000
I30.1 Infective pericarditis	0.000	0.705	0.295
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.294	0.705	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.294	0.705	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.294	0.705	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.294	0.705	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.294	0.705	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.294	0.705	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.294	0.705	0.000
O45.8 Other premature separation of placenta	0.293	0.707	0.000
O45.0 Premature separation of placenta with coagulation defect	0.293	0.707	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.708	0.292
I05.8 Other mitral valve diseases	0.000	0.710	0.290
O21.9 Vomiting of pregnancy, unspecified	0.284	0.715	0.000
I45.8 Other specified conduction disorders	0.000	0.716	0.284
I05.9 Mitral valve disease, unspecified	0.000	0.719	0.281
I08.9 Multiple valve disease, unspecified	0.000	0.719	0.281
O45.9 Premature separation of placenta, unspecified	0.279	0.720	0.000
O97 Death from sequelae of direct obstetric causes	0.278	0.721	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.278	0.721	0.000
O95 Obstetric death of unspecified cause	0.278	0.721	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.278	0.721	0.000
O43.9 Placental disorder, unspecified	0.278	0.722	0.000
O43.2 Morbidly adherent placenta	0.278	0.722	0.000
I45.3 Trifascicular block	0.000	0.722	0.278
I47 Paroxysmal tachycardia	0.000	0.723	0.277
I09.8 Other specified rheumatic heart diseases	0.000	0.726	0.274
I09.2 Chronic rheumatic pericarditis	0.000	0.726	0.274
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.726	0.274
I09.0 Rheumatic myocarditis	0.000	0.726	0.274
I30.8 Other forms of acute pericarditis	0.000	0.726	0.273
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.726	0.273
I45.0 Right fascicular block	0.000	0.728	0.272
O36.6 Maternal care for excessive foetal growth	0.270	0.730	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.732	0.268
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.266	0.734	0.000
O20 Haemorrhage in early pregnancy	0.265	0.735	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.739	0.261
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.739	0.261
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.739	0.261
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.739	0.261
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.739	0.261
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.739	0.261
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.739	0.261
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.739	0.261
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.739	0.261
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.739	0.261
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.739	0.261
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.739	0.261
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.739	0.261
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.739	0.261
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.739	0.261
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.739	0.261
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.739	0.261
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.739	0.261
I48.4 Atypical atrial flutter	0.000	0.739	0.261
I48.3 Typical atrial flutter	0.000	0.739	0.261
I48.2 Chronic atrial fibrillation	0.000	0.739	0.261
I48.1 Persistent atrial fibrillation	0.000	0.739	0.261
I48.0 Paroxysmal atrial fibrillation	0.000	0.739	0.261
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.739	0.261
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.739	0.261
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.739	0.261
O43.1 Malformation of placenta	0.259	0.741	0.000
O46.8 Other antepartum haemorrhage	0.258	0.741	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.257	0.743	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.256	0.743	0.000
O41.1 Infection of amniotic sac and membranes	0.256	0.744	0.000
I47.2 Ventricular tachycardia	0.000	0.744	0.256
I46.0 Cardiac arrest with successful resuscitation	0.000	0.746	0.254
I45.4 Nonspecific intraventricular block	0.000	0.750	0.250
O02.9 Abnormal product of conception, unspecified	0.250	0.750	0.000
O02.8 Other specified abnormal products of conception	0.250	0.750	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.752	0.247
I46.1 Sudden cardiac death, so described	0.000	0.753	0.247
I45.5 Other specified heart block	0.000	0.753	0.247
O32 Maternal care for known or suspected malpresentation of foetus	0.247	0.753	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.246	0.754	0.000
I20 Angina pectoris	0.000	0.758	0.242
O44.1 Placenta praevia with haemorrhage	0.240	0.760	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.760	0.240
I06.8 Other rheumatic aortic valve diseases	0.000	0.760	0.240
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.760	0.240
I06.1 Rheumatic aortic insufficiency	0.000	0.760	0.240
O41.0 Oligohydramnios	0.239	0.761	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.762	0.238
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.764	0.236
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.232	0.767	0.000
I02 Rheumatic chorea	0.000	0.770	0.230
I01 Rheumatic fever with heart involvement	0.000	0.770	0.230
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.228	0.772	0.000
I45.2 Bifascicular block	0.000	0.773	0.227
I40.8 Other acute myocarditis	0.000	0.775	0.225
I40.1 Isolated myocarditis	0.000	0.775	0.225
I07.9 Tricuspid valve disease, unspecified	0.000	0.775	0.225
I07.8 Other tricuspid valve diseases	0.000	0.775	0.225
I07.2 Tricuspid stenosis with insufficiency	0.000	0.775	0.225
I07.0 Tricuspid stenosis	0.000	0.775	0.225
O82.1 Delivery by emergency Caesarean section	0.224	0.775	0.000
O36.8 Maternal care for other specified foetal problems	0.220	0.780	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.220	0.780	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.781	0.219
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.781	0.219
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.781	0.219
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.781	0.219
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.781	0.219
I31 Other diseases of pericardium	0.000	0.781	0.219
I34.1 Mitral (valve) prolapse	0.000	0.783	0.217
O00.8 Other ectopic pregnancy	0.217	0.783	0.000
O00.2 Ovarian pregnancy	0.217	0.783	0.000
O00.0 Abdominal pregnancy	0.217	0.783	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.217	0.783	0.000
O32.4 Maternal care for high head at term	0.215	0.785	0.000
I49 Other cardiac arrhythmias	0.000	0.788	0.212
I40.0 Infective myocarditis	0.000	0.792	0.208
O43.8 Other placental disorders	0.206	0.793	0.000
I07.1 Tricuspid insufficiency	0.000	0.797	0.203
O96.9 Death from unspecified obstetric cause	0.200	0.800	0.000
O96.1 Death from indirect obstetric cause	0.200	0.800	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations