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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10965219
log Bayes Factor = 150.789
Chromosome 9   position 22,053,687  (GRCh37) Explore rs10965219 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.5 Skin of trunk
0.000 0.000 1.000
H40.9 Glaucoma, unspecified
1.000 0.000 0.000
H40.1 Primary open-angle glaucoma
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I21.9 Acute myocardial infarction, unspecified
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
I20.0 Unstable angina
1.000 0.000 0.000
H40 Glaucoma
1.000 0.000 0.000
C44.3 Skin of other and unspecified parts of face
0.000 0.000 1.000
I22 Subsequent myocardial infarction
1.000 0.000 0.000
I73.9 Peripheral vascular disease, unspecified
1.000 0.000 0.000
C71 Malignant neoplasm of brain
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
I73 Other peripheral vascular diseases
1.000 0.000 0.000
I21.4 Acute subendocardial myocardial infarction
1.000 0.000 0.000
C71.9 Brain, unspecified
0.000 0.001 0.999
C44.0 Skin of lip
0.000 0.002 0.998
C44.1 Skin of eyelid, including canthus
0.000 0.002 0.998
I22.9 Subsequent myocardial infarction of unspecified site
0.996 0.004 0.000
C71.1 Frontal lobe
0.000 0.006 0.994
C44.4 Skin of scalp and neck
0.000 0.007 0.993
I21.1 Acute transmural myocardial infarction of inferior wall
0.993 0.007 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.993 0.007 0.000
I72 Other aneurysm
0.981 0.019 0.000
I74 Arterial embolism and thrombosis
0.974 0.026 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.027 0.973
I77 Other disorders of arteries and arterioles
0.973 0.027 0.000
I24 Other acute ischaemic heart diseases
0.971 0.029 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.970 0.030 0.000
I77.1 Stricture of artery
0.967 0.033 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.964 0.036 0.000
I70 Atherosclerosis
0.959 0.041 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.958 0.042 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.054 0.946
H40.0 Glaucoma suspect
0.946 0.054 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.941 0.059 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.930 0.070 0.000
C71.2 Temporal lobe
0.000 0.071 0.929
I22.0 Subsequent myocardial infarction of anterior wall
0.928 0.072 0.000
C71.3 Parietal lobe
0.000 0.076 0.924
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.000 0.077 0.923
I70.2 Atherosclerosis of arteries of the extremities
0.922 0.078 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.081 0.919
C71.8 Overlapping lesion of brain
0.000 0.085 0.915
I25.5 Ischaemic cardiomyopathy
0.910 0.090 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.000 0.099 0.901
D05 Carcinoma in situ of breast
0.000 0.099 0.901
Chapter II Neoplasms
0.000 0.100 0.900
D00-D09 In situ neoplasms
0.000 0.102 0.898
I24.8 Other forms of acute ischaemic heart disease
0.890 0.110 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.888 0.112 0.000
C71.0 Cerebrum, except lobes and ventricles
0.000 0.118 0.882
Chapter IX Diseases of the circulatory system
0.872 0.128 0.000
I72.3 Aneurysm of iliac artery
0.860 0.140 0.000
Z82.3 Family history of stroke
0.858 0.142 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.858 0.142 0.000
C15-C26 Malignant neoplasms of digestive organs
0.000 0.149 0.851
I25.4 Coronary artery aneurysm
0.850 0.150 0.000
I20.8 Other forms of angina pectoris
0.848 0.152 0.000
I70.1 Atherosclerosis of renal artery
0.842 0.158 0.000
Z95.3 Presence of xenogenic heart valve
0.839 0.161 0.000
C15 Malignant neoplasm of oesophagus
0.000 0.165 0.835
I73.8 Other specified peripheral vascular diseases
0.823 0.177 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.000 0.181 0.819
I25.3 Aneurysm of heart
0.814 0.186 0.000
I72.0 Aneurysm of carotid artery
0.811 0.189 0.000
C15.5 Lower third of oesophagus
0.000 0.190 0.810
I72.9 Aneurysm of unspecified site
0.809 0.191 0.000
D05.7 Other carcinoma in situ of breast
0.000 0.192 0.808
I21.2 Acute transmural myocardial infarction of other sites
0.807 0.193 0.000
I72.1 Aneurysm of artery of upper extremity
0.806 0.194 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.805 0.195 0.000
C15.9 Oesophagus, unspecified
0.000 0.197 0.803
I22.8 Subsequent myocardial infarction of other sites
0.803 0.197 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.793 0.207 0.000
C21 Malignant neoplasm of anus and anal canal
0.000 0.217 0.783
I77.0 Arteriovenous fistula, acquired
0.779 0.221 0.000
C16 Malignant neoplasm of stomach
0.000 0.225 0.775
I72.4 Aneurysm of artery of lower extremity
0.772 0.228 0.000
H40.2 Primary angle-closure glaucoma
0.769 0.231 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.000 0.232 0.768
I72.8 Aneurysm of other specified arteries
0.767 0.233 0.000
D02.0 Larynx
0.000 0.237 0.763
I72.2 Aneurysm of renal artery
0.762 0.238 0.000
C17 Malignant neoplasm of small intestine
0.000 0.238 0.762
I70.10 Atherosclerosis of renal artery (without gangrene)
0.758 0.242 0.000
C16.0 Cardia
0.000 0.249 0.751
I73.1 Thromboangiitis obliterans [Buerger]
0.744 0.255 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.000 0.260 0.740
I74.8 Embolism and thrombosis of other arteries
0.732 0.268 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.731 0.269 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.000 0.270 0.730
I77.3 Arterial fibromuscular dysplasia
0.726 0.274 0.000
H40.3 Glaucoma secondary to eye trauma
0.723 0.277 0.000
I25.6 Silent myocardial ischaemia
0.721 0.279 0.000
C71.7 Brain stem
0.000 0.282 0.718
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.718 0.282 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.000 0.282 0.718
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
H40.6 Glaucoma secondary to drugs
0.717 0.283 0.000
C71.5 Cerebral ventricle
0.000 0.283 0.717
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.288 0.711
I70.8 Atherosclerosis of other arteries
0.710 0.290 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.705 0.295 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.703 0.296 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.703 0.296 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.703 0.297 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.000 0.298 0.702
C71.6 Cerebellum
0.000 0.302 0.698
I77.5 Necrosis of artery
0.697 0.302 0.000
I77.4 Coeliac artery compression syndrome
0.697 0.302 0.000
C32 Malignant neoplasm of larynx
0.000 0.314 0.686
C40-C41 Malignant neoplasms of bone and articular cartilage
0.000 0.317 0.683
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.676 0.324 0.000
D05.0 Lobular carcinoma in situ
0.000 0.326 0.674
C02.9 Tongue, unspecified
0.000 0.329 0.671
C08 Malignant neoplasm of other and unspecified major salivary glands
0.000 0.329 0.671
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.000 0.330 0.670
I21.3 Acute transmural myocardial infarction of unspecified site
0.668 0.332 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.663 0.336 0.000
H40.8 Other glaucoma
0.653 0.347 0.000
I70.9 Generalised and unspecified atherosclerosis
0.651 0.349 0.000
C20 Malignant neoplasm of rectum
0.000 0.352 0.648
C16.5 Lesser curvature of stomach, unspecified
0.000 0.353 0.647
C17.0 Duodenum
0.000 0.357 0.643
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.642 0.358 0.000
H40.4 Glaucoma secondary to eye inflammation
0.630 0.370 0.000
C21.0 Anus, unspecified
0.000 0.370 0.630
I00-I02 Acute rheumatic fever
0.625 0.375 0.000
C71.4 Occipital lobe
0.000 0.380 0.620
C32.9 Larynx, unspecified
0.000 0.381 0.619
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.617 0.383 0.000
I77.2 Rupture of artery
0.616 0.384 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.615 0.385 0.000
I60-I69 Cerebrovascular diseases
0.614 0.386 0.000
I23 Certain current complications following acute myocardial infarction
0.613 0.386 0.000
C00 Malignant neoplasm of lip
0.000 0.395 0.605
C17.9 Small intestine, unspecified
0.000 0.395 0.605
C23 Malignant neoplasm of gallbladder
0.000 0.396 0.604
I70.11 Atherosclerosis of renal artery (with gangrene)
0.604 0.396 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.602 0.398 0.000
C44.7 Skin of lower limb, including hip
0.000 0.401 0.599
C15.8 Overlapping lesion of oesophagus
0.000 0.401 0.599
C15.2 Abdominal part of oesophagus
0.000 0.401 0.599
C15.0 Cervical part of oesophagus
0.000 0.406 0.594
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.000 0.411 0.589
C17.1 Jejunum
0.000 0.412 0.588
D02.4 Respiratory system, unspecified
0.000 0.413 0.587
D02.3 Other parts of respiratory system
0.000 0.413 0.587
D02.2 Bronchus and lung
0.000 0.413 0.587
D02.1 Trachea
0.000 0.413 0.587
C32.0 Glottis
0.000 0.414 0.586
D07.2 Vagina
0.000 0.414 0.586
C08.9 Major salivary gland, unspecified
0.000 0.414 0.586
I24.1 Dressler's syndrome
0.586 0.414 0.000
C31 Malignant neoplasm of accessory sinuses
0.000 0.420 0.580
C07 Malignant neoplasm of parotid gland
0.000 0.428 0.572
D07.1 Vulva
0.000 0.428 0.572
C30 Malignant neoplasm of nasal cavity and middle ear
0.000 0.429 0.571
Z82.1 Family history of blindness and visual loss
0.571 0.429 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.569 0.431 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.432 0.568
C70 Malignant neoplasm of meninges
0.000 0.432 0.567
C21.1 Anal canal
0.000 0.435 0.565
D04 Carcinoma in situ of skin
0.000 0.436 0.564
C16.1 Fundus of stomach
0.000 0.436 0.564
C17.2 Ileum
0.000 0.438 0.562
C21.2 Cloacogenic zone
0.000 0.438 0.561
I73.0 Raynaud's syndrome
0.561 0.439 0.000
Z95.0 Presence of cardiac pacemaker
0.561 0.439 0.000
C16.8 Overlapping lesion of stomach
0.000 0.443 0.557
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.557 0.443 0.000
D07.5 Prostate
0.000 0.443 0.557
D01.2 Rectum
0.000 0.446 0.554
I65.2 Occlusion and stenosis of carotid artery
0.554 0.446 0.000
C16.6 Greater curvature of stomach, unspecified
0.000 0.447 0.553
C02.4 Lingual tonsil
0.000 0.447 0.552
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.552 0.448 0.000
C37 Malignant neoplasm of thymus
0.000 0.449 0.551
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.449 0.551
D05.1 Intraductal carcinoma in situ
0.000 0.449 0.551
C01 Malignant neoplasm of base of tongue
0.000 0.451 0.549
C17.8 Overlapping lesion of small intestine
0.000 0.454 0.546
C17.3 Meckel's diverticulum
0.000 0.454 0.546
I67 Other cerebrovascular diseases
0.544 0.456 0.000
Z82.2 Family history of deafness and hearing loss
0.542 0.457 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.000 0.463 0.537
C38 Malignant neoplasm of heart, mediastinum and pleura
0.000 0.463 0.537
C16.9 Stomach, unspecified
0.000 0.466 0.534
D01.0 Colon
0.000 0.466 0.534
I74.5 Embolism and thrombosis of iliac artery
0.533 0.467 0.000
C13 Malignant neoplasm of hypopharynx
0.000 0.467 0.533
I67.9 Cerebrovascular disease, unspecified
0.533 0.467 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.531 0.469 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.000 0.469 0.531
C15.1 Thoracic part of oesophagus
0.000 0.472 0.528
C02.1 Border of tongue
0.000 0.472 0.528
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.000 0.476 0.524
C10 Malignant neoplasm of oropharynx
0.000 0.476 0.524
D07.6 Other and unspecified male genital organs
0.000 0.476 0.523
D07.3 Other and unspecified female genital organs
0.000 0.476 0.523
D07.0 Endometrium
0.000 0.476 0.523
C04 Malignant neoplasm of floor of mouth
0.000 0.477 0.523
C15.3 Upper third of oesophagus
0.000 0.478 0.522
C05 Malignant neoplasm of palate
0.000 0.481 0.519
C11 Malignant neoplasm of nasopharynx
0.000 0.481 0.518
H40.5 Glaucoma secondary to other eye disorders
0.516 0.484 0.000
C08.0 Submandibular gland
0.000 0.485 0.515
C02.8 Overlapping lesion of tongue
0.000 0.485 0.514
C02.3 Anterior two-thirds of tongue, part unspecified
0.000 0.485 0.514
C02.0 Dorsal surface of tongue
0.000 0.485 0.514
D04.3 Skin of other and unspecified parts of face
0.000 0.487 0.513
C06 Malignant neoplasm of other and unspecified parts of mouth
0.000 0.490 0.510
Z95.2 Presence of prosthetic heart valve
0.510 0.490 0.000
C02.2 Ventral surface of tongue
0.000 0.491 0.509
I70.81 Atherosclerosis of other arteries (with gangrene)
0.509 0.491 0.000
I79.1 Aortitis in diseases classified elsewhere
0.505 0.494 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.505 0.494 0.000
D01.9 Digestive organ, unspecified
0.000 0.496 0.503
D01.7 Other specified digestive organs
0.000 0.496 0.503
D01.5 Liver, gallbladder and bile ducts
0.000 0.496 0.503
D01.4 Other and unspecified parts of intestine
0.000 0.496 0.503
D01.1 Rectosigmoid junction
0.000 0.496 0.503
C16.4 Pylorus
0.000 0.498 0.501
C03 Malignant neoplasm of gum
0.000 0.504 0.495
I62 Other nontraumatic intracranial haemorrhage
0.495 0.505 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.000 0.505 0.494
I70.0 Atherosclerosis of aorta
0.492 0.507 0.001
C32.8 Overlapping lesion of larynx
0.000 0.508 0.492
C32.3 Laryngeal cartilage
0.000 0.508 0.492
C32.2 Subglottis
0.000 0.508 0.492
D09 Carcinoma in situ of other and unspecified sites
0.000 0.508 0.492
D04.2 Skin of ear and external auricular canal
0.000 0.509 0.491
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.000 0.510 0.490
C72.0 Spinal cord
0.000 0.511 0.489
C33 Malignant neoplasm of trachea
0.000 0.512 0.488
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.518 0.482
C08.8 Overlapping lesion of major salivary glands
0.000 0.519 0.481
C08.1 Sublingual gland
0.000 0.519 0.481
C72.9 Central nervous system, unspecified
0.000 0.519 0.480
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.000 0.519 0.480
C72.5 Other and unspecified cranial nerves
0.000 0.519 0.480
C72.4 Acoustic nerve
0.000 0.519 0.480
C72.3 Optic nerve
0.000 0.519 0.480
C72.2 Olfactory nerve
0.000 0.519 0.480
C72.1 Cauda equina
0.000 0.519 0.480
D01.3 Anus and anal canal
0.000 0.521 0.479
I67.0 Dissection of cerebral arteries, nonruptured
0.479 0.521 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.477 0.523 0.000
C00.0 External upper lip
0.000 0.525 0.474
C32.1 Supraglottis
0.000 0.528 0.472
C00.1 External lower lip
0.000 0.533 0.467
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.466 0.533 0.000
C12 Malignant neoplasm of pyriform sinus
0.000 0.533 0.466
C31.0 Maxillary sinus
0.000 0.535 0.465
C69 Malignant neoplasm of eye and adnexa
0.000 0.537 0.462
D07.4 Penis
0.000 0.538 0.462
C14.0 Pharynx, unspecified
0.000 0.540 0.460
C30.0 Nasal cavity
0.000 0.550 0.450
I02 Rheumatic chorea
0.448 0.552 0.000
I01 Rheumatic fever with heart involvement
0.448 0.552 0.000
I00 Rheumatic fever without mention of heart involvement
0.448 0.552 0.000
I66.2 Occlusion and stenosis of posterior cerebral artery
0.441 0.559 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.559 0.441
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.440 0.560 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.440 0.560 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.440 0.560 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.440 0.560 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.440 0.560 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.440 0.560 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.440 0.560 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.440 0.560 0.000
D04.9 Skin, unspecified
0.000 0.563 0.437
C00.8 Overlapping lesion of lip
0.000 0.566 0.434
C00.6 Commissure of lip
0.000 0.566 0.434
C00.5 Lip, unspecified, inner aspect
0.000 0.566 0.434
C00.4 Lower lip, inner aspect
0.000 0.566 0.434
C00.3 Upper lip, inner aspect
0.000 0.566 0.434
C00.2 External lip, unspecified
0.000 0.566 0.434
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.434 0.566 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.429 0.570 0.000
C50-C50 Malignant neoplasm of breast
0.000 0.571 0.429
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.000 0.578 0.422
C14.2 Waldeyer's ring
0.000 0.578 0.422
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.420 0.579 0.000
H40-H42 Glaucoma
0.418 0.582 0.000
D06 Carcinoma in situ of cervix uteri
0.000 0.582 0.418
C16.3 Pyloric antrum
0.000 0.584 0.416
C00.9 Lip, unspecified
0.000 0.584 0.416
C31.9 Accessory sinus, unspecified
0.000 0.584 0.416
C31.8 Overlapping lesion of accessory sinuses
0.000 0.584 0.416
C31.3 Sphenoidal sinus
0.000 0.584 0.416
C31.2 Frontal sinus
0.000 0.584 0.416
C31.1 Ethmoidal sinus
0.000 0.584 0.416
I66.3 Occlusion and stenosis of cerebellar arteries
0.414 0.586 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.412 0.588 0.000
I20.1 Angina pectoris with documented spasm
0.412 0.588 0.000
C30.1 Middle ear
0.000 0.590 0.409
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.408 0.592 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.408 0.592 0.000
C24.8 Overlapping lesion of biliary tract
0.000 0.592 0.408
C70.9 Meninges, unspecified
0.000 0.593 0.407
C70.1 Spinal meninges
0.000 0.593 0.407
I71 Aortic aneurysm and dissection
0.407 0.593 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.406 0.594 0.000
C40.0 Scapula and long bones of upper limb
0.000 0.594 0.406
C05.9 Palate, unspecified
0.000 0.595 0.405
D04.8 Skin of other sites
0.000 0.595 0.404
D04.0 Skin of lip
0.000 0.595 0.404
C16.2 Body of stomach
0.000 0.599 0.400
C24.9 Biliary tract, unspecified
0.000 0.602 0.398
C13.0 Postcricoid region
0.000 0.603 0.397
I66.8 Occlusion and stenosis of other cerebral artery
0.396 0.604 0.000
I66.1 Occlusion and stenosis of anterior cerebral artery
0.396 0.604 0.000
I62.1 Nontraumatic extradural haemorrhage
0.396 0.604 0.000
C24.0 Extrahepatic bile duct
0.000 0.605 0.395
I68 Cerebrovascular disorders in diseases classified elsewhere
0.394 0.605 0.000
I77.8 Other specified disorders of arteries and arterioles
0.394 0.606 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.393 0.607 0.000
I65.1 Occlusion and stenosis of basilar artery
0.393 0.607 0.000
C24.1 Ampulla of Vater
0.000 0.609 0.391
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.390 0.610 0.000
I67.5 Moyamoya disease
0.390 0.610 0.000
I67.4 Hypertensive encephalopathy
0.390 0.610 0.000
I67.3 Progressive vascular leukoencephalopathy
0.390 0.610 0.000
C38.4 Pleura
0.000 0.610 0.390
C41.9 Bone and articular cartilage, unspecified
0.000 0.611 0.388
C38.3 Mediastinum, part unspecified
0.000 0.614 0.386
D00.2 Stomach
0.000 0.615 0.385
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.000 0.615 0.385
C38.2 Posterior mediastinum
0.000 0.615 0.385
C38.1 Anterior mediastinum
0.000 0.615 0.385
C38.0 Heart
0.000 0.615 0.385
C15.4 Middle third of oesophagus
0.000 0.617 0.382
C44.9 Malignant neoplasm of skin, unspecified
0.001 0.617 0.382
D03 Melanoma in situ
0.000 0.618 0.382
C13.8 Overlapping lesion of hypopharynx
0.000 0.618 0.382
C13.2 Posterior wall of hypopharynx
0.000 0.618 0.382
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.000 0.618 0.382
C40.2 Long bones of lower limb
0.000 0.618 0.381
C39.9 Ill-defined sites within the respiratory system
0.000 0.619 0.381
C39.8 Overlapping lesion of respiratory and intrathoracic organs
0.000 0.619 0.381
C39.0 Upper respiratory tract, part unspecified
0.000 0.619 0.381
C06.0 Cheek mucosa
0.000 0.619 0.380
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.620 0.380
C04.9 Floor of mouth, unspecified
0.000 0.622 0.378
C40.9 Bone and articular cartilage of limb, unspecified
0.000 0.624 0.376
C40.8 Overlapping lesion of bone and articular cartilage of limbs
0.000 0.624 0.376
C40.3 Short bones of lower limb
0.000 0.624 0.376
C40.1 Short bones of upper limb
0.000 0.624 0.376
C10.8 Overlapping lesion of oropharynx
0.000 0.624 0.376
C10.4 Branchial cleft
0.000 0.624 0.376
C10.3 Posterior wall of oropharynx
0.000 0.624 0.376
C10.2 Lateral wall of oropharynx
0.000 0.624 0.376
C10.1 Anterior surface of epiglottis
0.000 0.624 0.376
C10.0 Vallecula
0.000 0.624 0.376
C04.8 Overlapping lesion of floor of mouth
0.000 0.625 0.375
C04.1 Lateral floor of mouth
0.000 0.625 0.375
C05.8 Overlapping lesion of palate
0.000 0.628 0.372
C05.2 Uvula
0.000 0.628 0.372
C06.2 Retromolar area
0.000 0.628 0.372
C11.8 Overlapping lesion of nasopharynx
0.000 0.628 0.372
C11.3 Anterior wall of nasopharynx
0.000 0.628 0.372
C11.2 Lateral wall of nasopharynx
0.000 0.628 0.372
C11.1 Posterior wall of nasopharynx
0.000 0.628 0.372
C11.0 Superior wall of nasopharynx
0.000 0.628 0.372
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.371 0.629 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.001 0.631 0.368
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.366 0.633 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.000 0.634 0.366
C06.1 Vestibule of mouth
0.000 0.634 0.366
D04.6 Skin of upper limb, including shoulder
0.000 0.638 0.362
D04.4 Skin of scalp and neck
0.000 0.639 0.361
C60-C63 Malignant neoplasms of male genital organs
0.000 0.639 0.361
I61 Intracerebral haemorrhage
0.361 0.639 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.359 0.641 0.000
I67.2 Cerebral atherosclerosis
0.358 0.642 0.000
C41.2 Vertebral column
0.000 0.642 0.357
D09.9 Carcinoma in situ, unspecified
0.000 0.644 0.356
C69.6 Orbit
0.000 0.644 0.355
C41.0 Bones of skull and face
0.000 0.644 0.355
C03.9 Gum, unspecified
0.000 0.644 0.355
C03.0 Upper gum
0.000 0.644 0.355
C05.0 Hard palate
0.000 0.645 0.355
C41.8 Overlapping lesion of bone and articular cartilage
0.000 0.645 0.355
C41.3 Ribs, sternum and clavicle
0.000 0.645 0.355
I70.01 Atherosclerosis of aorta (with gangrene)
0.353 0.647 0.001
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.000 0.647 0.353
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.352 0.647 0.001
D09.3 Thyroid and other endocrine glands
0.000 0.647 0.352
D09.2 Eye
0.000 0.647 0.352
C42.4 hematopoietic and reticuloendothelial systems: Hematopoietic system, NOS (ICD-O-3 specific)
0.000 0.649 0.351
C42.3 hematopoietic and reticuloendothelial systems: Reticuloendothelial system, NOS (ICD-O-3 specific)
0.000 0.649 0.351
C42.2 hematopoietic and reticuloendothelial systems: spleen (ICD-O-3 specific)
0.000 0.649 0.351
C42.1 hematopoietic and reticuloendothelial systems: bone marrow (ICD-O-3 specific)
0.000 0.649 0.351
C42.0 hematopoietic and reticuloendothelial systems: blood (ICD-O-3 specific)
0.000 0.649 0.351
D00.0 Lip, oral cavity and pharynx
0.000 0.649 0.351
C10.9 Oropharynx, unspecified
0.000 0.651 0.349
I66.0 Occlusion and stenosis of middle cerebral artery
0.347 0.653 0.000
C13.9 Hypopharynx, unspecified
0.000 0.654 0.346
C26.8 Overlapping lesion of digestive system
0.000 0.654 0.346
C26.1 Spleen
0.000 0.654 0.346
C04.0 Anterior floor of mouth
0.000 0.655 0.344
D09.7 Carcinoma in situ of other specified sites
0.000 0.657 0.343
I60 Subarachnoid haemorrhage
0.341 0.659 0.000
C11.9 Nasopharynx, unspecified
0.000 0.660 0.339
D04.1 Skin of eyelid, including canthus
0.000 0.660 0.339
C41.4 Pelvic bones, sacrum and coccyx
0.000 0.662 0.338
I61.5 Intracerebral haemorrhage, intraventricular
0.338 0.662 0.000
I23.8 Other current complications following acute myocardial infarction
0.336 0.663 0.000
D03.4 Melanoma in situ of scalp and neck
0.000 0.664 0.336
C09 Malignant neoplasm of tonsil
0.000 0.665 0.335
C69.8 Overlapping lesion of eye and adnexa
0.000 0.668 0.332
C69.5 Lachrymal gland and duct
0.000 0.668 0.332
C69.4 Ciliary body
0.000 0.668 0.332
C69.2 Retina
0.000 0.668 0.332
C69.1 Cornea
0.000 0.668 0.332
C41.1 Mandible
0.000 0.669 0.331
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.331 0.669 0.000
D00.1 Oesophagus
0.000 0.674 0.326
I71.1 Thoracic aortic aneurysm, ruptured
0.325 0.675 0.000
I01.9 Acute rheumatic heart disease, unspecified
0.321 0.678 0.000
I01.8 Other acute rheumatic heart disease
0.321 0.678 0.000
I01.2 Acute rheumatic myocarditis
0.321 0.678 0.000
I01.1 Acute rheumatic endocarditis
0.321 0.678 0.000
I01.0 Acute rheumatic pericarditis
0.321 0.678 0.000
I02.9 Rheumatic chorea without heart involvement
0.321 0.678 0.000
I02.0 Rheumatic chorea with heart involvement
0.321 0.678 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.000 0.684 0.316
C46 Kaposi's sarcoma
0.000 0.684 0.316
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.315 0.685 0.000
C05.1 Soft palate
0.000 0.686 0.314
C26.9 Ill-defined sites within the digestive system
0.000 0.686 0.314
C70.0 Cerebral meninges
0.001 0.687 0.313
D09.1 Other and unspecified urinary organs
0.000 0.687 0.312
C69.9 Eye, unspecified
0.000 0.687 0.312
C69.0 Conjunctiva
0.000 0.688 0.311
D06.0 Endocervix
0.000 0.694 0.305
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.303 0.697 0.000
D06.1 Exocervix
0.000 0.699 0.301
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.699 0.301
C03.1 Lower gum
0.000 0.700 0.300
I60.8 Other subarachnoid haemorrhage
0.300 0.700 0.000
H42 Glaucoma in diseases classified elsewhere
0.300 0.700 0.000
D06.7 Other parts of cervix
0.000 0.700 0.300
D03.7 Melanoma in situ of lower limb, including hip
0.000 0.701 0.299
C06.9 Mouth, unspecified
0.000 0.705 0.295
I71.8 Aortic aneurysm of unspecified site, ruptured
0.292 0.708 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.292 0.708 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.291 0.709 0.000
I05-I09 Chronic rheumatic heart diseases
0.289 0.711 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.288 0.712 0.000
C48.0 Retroperitoneum
0.000 0.715 0.285
C74 Malignant neoplasm of adrenal gland
0.000 0.716 0.284
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.283 0.717 0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.283 0.717 0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.283 0.717 0.000
I63 Cerebral infarction
0.279 0.721 0.000
C48.2 Peritoneum, unspecified
0.000 0.723 0.277
D09.0 Bladder
0.000 0.725 0.275
D03.9 Melanoma in situ, unspecified
0.000 0.726 0.274
D03.0 Melanoma in situ of lip
0.000 0.726 0.274
D03.1 Melanoma in situ of eyelid, including canthus
0.000 0.726 0.274
C18 Malignant neoplasm of colon
0.000 0.726 0.274
C60 Malignant neoplasm of penis
0.000 0.731 0.269
C26.0 Intestinal tract, part unspecified
0.000 0.732 0.268
I78 Diseases of capillaries
0.267 0.732 0.001
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.268 0.732 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.000 0.732 0.268
D03.2 Melanoma in situ of ear and external auricular canal
0.000 0.741 0.258
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.256 0.744 0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.000 0.747 0.253
D03.8 Melanoma in situ of other sites
0.000 0.748 0.252
I61.4 Intracerebral haemorrhage in cerebellum
0.251 0.748 0.000
D04.5 Skin of trunk
0.000 0.749 0.251
C18.3 Hepatic flexure
0.000 0.750 0.250
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.250 0.750 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.249 0.751 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.248 0.752 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.244 0.755 0.000
C09.8 Overlapping lesion of tonsil
0.000 0.760 0.240
C09.0 Tonsillar fossa
0.000 0.760 0.240
D03.6 Melanoma in situ of upper limb, including shoulder
0.000 0.760 0.240
I60.9 Subarachnoid haemorrhage, unspecified
0.239 0.761 0.000
I68.0 Cerebral amyloid angiopathy
0.237 0.763 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.235 0.765 0.000
C18.2 Ascending colon
0.000 0.765 0.235

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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