TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs17630235
log Bayes Factor = 80.0182
Chromosome 12   position 112,591,686  (GRCh37) Explore rs17630235 on Ensembl!
Variant rs17630235 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
1.000 0.000 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Z95.2 Presence of prosthetic heart valve
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
Z95.4 Presence of other heart-valve replacement
1.000 0.000 0.000
C77.3 Axillary and upper limb lymph nodes
0.000 0.001 0.999
Z95.1 Presence of aortocoronary bypass graft
0.999 0.001 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.002 0.998
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.007 0.993
I25.9 Chronic ischaemic heart disease, unspecified
0.991 0.009 0.000
E03 Other hypothyroidism
0.991 0.009 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.011 0.989
I70-I79 Diseases of arteries, arterioles and capillaries
0.985 0.015 0.000
E00-E07 Disorders of thyroid gland
0.983 0.017 0.000
C78.7 Secondary malignant neoplasm of liver
0.000 0.019 0.981
I25.5 Ischaemic cardiomyopathy
0.979 0.021 0.000
I20 Angina pectoris
0.967 0.033 0.000
C77.9 Lymph node, unspecified
0.000 0.034 0.966
E05 Thyrotoxicosis [hyperthyroidism]
0.965 0.035 0.000
I73 Other peripheral vascular diseases
0.959 0.041 0.000
I20.9 Angina pectoris, unspecified
0.956 0.044 0.000
I73.9 Peripheral vascular disease, unspecified
0.955 0.045 0.000
I74 Arterial embolism and thrombosis
0.948 0.052 0.000
E05.9 Thyrotoxicosis, unspecified
0.947 0.053 0.000
I22 Subsequent myocardial infarction
0.947 0.053 0.000
E10 Insulin-dependent diabetes mellitus
0.931 0.069 0.000
Z95.3 Presence of xenogenic heart valve
0.927 0.073 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.922 0.078 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.914 0.086 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.912 0.088 0.000
E10-E14 Diabetes mellitus
0.911 0.089 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.000 0.095 0.905
E05.0 Thyrotoxicosis with diffuse goitre
0.903 0.097 0.000
I74.5 Embolism and thrombosis of iliac artery
0.897 0.103 0.000
E10.5 With peripheral circulatory complications
0.887 0.113 0.000
I35 Nonrheumatic aortic valve disorders
0.884 0.116 0.000
I12 Hypertensive renal disease
0.883 0.117 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.000 0.117 0.883
I30-I52 Other forms of heart disease
0.880 0.120 0.000
I23 Certain current complications following acute myocardial infarction
0.880 0.120 0.000
E06 Thyroiditis
0.877 0.123 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.871 0.129 0.000
E10.1 With ketoacidosis
0.871 0.129 0.000
C78.2 Secondary malignant neoplasm of pleura
0.000 0.130 0.870
I21.4 Acute subendocardial myocardial infarction
0.869 0.131 0.000
I05-I09 Chronic rheumatic heart diseases
0.865 0.135 0.000
C77.2 Intra-abdominal lymph nodes
0.000 0.141 0.859
I35.0 Aortic (valve) stenosis
0.850 0.150 0.000
E10.4 With neurological complications
0.843 0.157 0.000
E10.9 Without complications
0.839 0.161 0.000
C77.4 Inguinal and lower limb lymph nodes
0.000 0.167 0.833
C77.8 Lymph nodes of multiple regions
0.000 0.177 0.823
I36 Nonrheumatic tricuspid valve disorders
0.820 0.180 0.000
E10.3 With ophthalmic complications
0.817 0.183 0.000
E10.2 With renal complications
0.816 0.184 0.000
C79 Secondary malignant neoplasm of other sites
0.000 0.185 0.815
I12.0 Hypertensive renal disease with renal failure
0.815 0.185 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.189 0.811
I05 Rheumatic mitral valve diseases
0.811 0.189 0.000
E20-E35 Disorders of other endocrine glands
0.805 0.195 0.000
I13 Hypertensive heart and renal disease
0.801 0.199 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.794 0.206 0.000
I23.8 Other current complications following acute myocardial infarction
0.793 0.207 0.000
E10.0 With coma
0.792 0.208 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.790 0.210 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.784 0.216 0.000
I25.4 Coronary artery aneurysm
0.781 0.219 0.000
I77 Other disorders of arteries and arterioles
0.779 0.221 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.777 0.223 0.000
E03.1 Congenital hypothyroidism without goitre
0.764 0.236 0.000
I15 Secondary hypertension
0.759 0.241 0.000
I25.6 Silent myocardial ischaemia
0.757 0.242 0.000
E03.8 Other specified hypothyroidism
0.756 0.244 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.752 0.248 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.750 0.250 0.000
I05.0 Mitral stenosis
0.748 0.252 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.000 0.253 0.747
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.255 0.745
I35.1 Aortic (valve) insufficiency
0.744 0.256 0.000
I20.8 Other forms of angina pectoris
0.743 0.257 0.000
I37 Pulmonary valve disorders
0.738 0.262 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.738 0.262 0.000
I38 Endocarditis, valve unspecified
0.736 0.264 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.735 0.265 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.734 0.266 0.000
I05.2 Mitral stenosis with insufficiency
0.733 0.267 0.000
I99 Other and unspecified disorders of circulatory system
0.731 0.269 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.273 0.727
I35.9 Aortic valve disorder, unspecified
0.725 0.275 0.000
E06.9 Thyroiditis, unspecified
0.724 0.276 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.000 0.281 0.719
E06.3 Autoimmune thyroiditis
0.717 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.717 0.283 0.000
E10.8 With unspecified complications
0.713 0.287 0.000
E03.5 Myxoedema coma
0.711 0.289 0.000
E03.4 Atrophy of thyroid (acquired)
0.711 0.289 0.000
E03.3 Postinfectious hypothyroidism
0.711 0.289 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.711 0.289 0.000
E23 Hypofunction and other disorders of pituitary gland
0.710 0.290 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.710 0.290 0.000
I70 Atherosclerosis
0.706 0.294 0.000
I22.8 Subsequent myocardial infarction of other sites
0.706 0.294 0.000
I77.6 Arteritis, unspecified
0.705 0.295 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.705 0.295 0.000
E00 Congenital iodine-deficiency syndrome
0.705 0.295 0.000
E27 Other disorders of adrenal gland
0.704 0.296 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.702 0.298 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.000 0.301 0.699
I73.8 Other specified peripheral vascular diseases
0.696 0.304 0.000
E20 Hypoparathyroidism
0.696 0.304 0.000
C76.0 Head, face and neck
0.000 0.305 0.695
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.694 0.306 0.000
E05.5 Thyroid crisis or storm
0.692 0.308 0.000
E05.4 Thyrotoxicosis factitia
0.692 0.308 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.692 0.308 0.000
I07 Rheumatic tricuspid valve diseases
0.688 0.312 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.686 0.314 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.682 0.318 0.000
I25.3 Aneurysm of heart
0.677 0.323 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.674 0.326 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.672 0.328 0.000
C50 Malignant neoplasm of breast
0.000 0.328 0.672
E10.7 With multiple complications
0.668 0.332 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.667 0.333 0.000
E06.1 Subacute thyroiditis
0.664 0.336 0.000
C50.9 Breast, unspecified
0.000 0.340 0.660
I13.1 Hypertensive heart and renal disease with renal failure
0.659 0.341 0.000
C50.8 Overlapping lesion of breast
0.000 0.342 0.658
C50.4 Upper-outer quadrant of breast
0.000 0.342 0.658
I37.1 Pulmonary valve insufficiency
0.656 0.344 0.000
I33 Acute and subacute endocarditis
0.655 0.345 0.000
E12 Malnutrition-related diabetes mellitus
0.653 0.346 0.000
I30 Acute pericarditis
0.652 0.347 0.000
E06.5 Other chronic thyroiditis
0.652 0.348 0.000
E27.1 Primary adrenocortical insufficiency
0.648 0.352 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.357 0.643
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.000 0.359 0.640
C80 Malignant neoplasm without specification of site
0.000 0.360 0.640
C50.1 Central portion of breast
0.000 0.362 0.638
I06 Rheumatic aortic valve diseases
0.636 0.364 0.000
E16 Other disorders of pancreatic internal secretion
0.633 0.367 0.000
I52 Other heart disorders in diseases classified elsewhere
0.631 0.369 0.000
I48 Atrial fibrillation and flutter
0.631 0.369 0.000
I41 Myocarditis in diseases classified elsewhere
0.631 0.369 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.631 0.369 0.000
I32 Pericarditis in diseases classified elsewhere
0.631 0.369 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.631 0.369 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.631 0.369 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.631 0.369 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.631 0.369 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.631 0.369 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.631 0.369 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.631 0.369 0.000
E22 Hyperfunction of pituitary gland
0.630 0.370 0.000
I00-I02 Acute rheumatic fever
0.629 0.370 0.000
E06.4 Drug-induced thyroiditis
0.629 0.371 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.629 0.371 0.000
E06.0 Acute thyroiditis
0.629 0.371 0.000
I21.9 Acute myocardial infarction, unspecified
0.629 0.371 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.372 0.628
I73.1 Thromboangiitis obliterans [Buerger]
0.627 0.373 0.000
E23.6 Other disorders of pituitary gland
0.614 0.386 0.000
E05.8 Other thyrotoxicosis
0.611 0.389 0.000
E28 Ovarian dysfunction
0.604 0.396 0.000
I20.1 Angina pectoris with documented spasm
0.603 0.397 0.000
I40 Acute myocarditis
0.602 0.398 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.602 0.398 0.000
E31 Polyglandular dysfunction
0.602 0.398 0.000
E27.2 Addisonian crisis
0.599 0.401 0.000
E25 Adrenogenital disorders
0.599 0.401 0.000
E23.2 Diabetes insipidus
0.597 0.403 0.000
C50.0 Nipple and areola
0.000 0.404 0.596
I43 Cardiomyopathy in diseases classified elsewhere
0.595 0.405 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.592 0.408 0.000
E50-E64 Other nutritional deficiencies
0.592 0.408 0.000
I15.1 Hypertension secondary to other renal disorders
0.590 0.410 0.000
I77.1 Stricture of artery
0.588 0.412 0.000
E20.9 Hypoparathyroidism, unspecified
0.588 0.412 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.588 0.412 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.588 0.412 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.588 0.412 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.588 0.412 0.000
E07 Other disorders of thyroid
0.588 0.412 0.000
I05.8 Other mitral valve diseases
0.586 0.414 0.000
E10.6 With other specified complications
0.586 0.414 0.000
I35.8 Other aortic valve disorders
0.586 0.414 0.000
I77.2 Rupture of artery
0.585 0.415 0.000
I05.1 Rheumatic mitral insufficiency
0.585 0.415 0.000
I15.0 Renovascular hypertension
0.584 0.416 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.582 0.418 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.000 0.418 0.582
C76.7 Other ill-defined sites
0.000 0.418 0.582
C76.5 Lower limb
0.000 0.418 0.582
C76.4 Upper limb
0.000 0.418 0.582
I12.9 Hypertensive renal disease without renal failure
0.580 0.420 0.000
I42 Cardiomyopathy
0.580 0.420 0.000
E22.1 Hyperprolactinaemia
0.578 0.421 0.000
C76.1 Thorax
0.000 0.423 0.577
E27.8 Other specified disorders of adrenal gland
0.577 0.423 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.577 0.423 0.000
E32 Diseases of thymus
0.577 0.423 0.000
E30 Disorders of puberty, not elsewhere classified
0.577 0.423 0.000
E16.2 Hypoglycaemia, unspecified
0.577 0.423 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.576 0.424 0.000
E23.0 Hypopituitarism
0.575 0.425 0.000
C76.2 Abdomen
0.000 0.425 0.575
I13.9 Hypertensive heart and renal disease, unspecified
0.574 0.425 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.574 0.425 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.574 0.425 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.573 0.427 0.000
I33.9 Acute endocarditis, unspecified
0.571 0.429 0.000
I28 Other diseases of pulmonary vessels
0.571 0.429 0.000
E34 Other endocrine disorders
0.568 0.432 0.000
C76.3 Pelvis
0.000 0.432 0.568
I74.8 Embolism and thrombosis of other arteries
0.564 0.436 0.000
I72 Other aneurysm
0.564 0.436 0.000
I07.1 Tricuspid insufficiency
0.562 0.438 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.561 0.439 0.000
I77.5 Necrosis of artery
0.559 0.441 0.000
I77.4 Coeliac artery compression syndrome
0.559 0.441 0.000
I77.3 Arterial fibromuscular dysplasia
0.559 0.441 0.000
C50-C50 Malignant neoplasm of breast
0.000 0.443 0.557
E13 Other specified diabetes mellitus
0.554 0.446 0.000
E20.1 Pseudohypoparathyroidism
0.552 0.448 0.000
E40-E46 Malnutrition
0.548 0.452 0.000
I26 Pulmonary embolism
0.547 0.453 0.000
I15.2 Hypertension secondary to endocrine disorders
0.547 0.453 0.000
E26 Hyperaldosteronism
0.546 0.453 0.000
I15.8 Other secondary hypertension
0.544 0.456 0.000
I31 Other diseases of pericardium
0.541 0.459 0.000
I30.1 Infective pericarditis
0.539 0.461 0.000
E15 Nondiabetic hypoglycaemic coma
0.538 0.462 0.000
I77.8 Other specified disorders of arteries and arterioles
0.537 0.463 0.000
I37.9 Pulmonary valve disorder, unspecified
0.529 0.470 0.000
I37.8 Other pulmonary valve disorders
0.529 0.470 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.529 0.470 0.000
C77.1 Intrathoracic lymph nodes
0.000 0.472 0.528
I42.2 Other hypertrophic cardiomyopathy
0.527 0.473 0.000
I79.1 Aortitis in diseases classified elsewhere
0.526 0.473 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.526 0.473 0.000
I46 Cardiac arrest
0.524 0.476 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.519 0.481 0.000
I51 Complications and ill-defined descriptions of heart disease
0.516 0.484 0.000
I77.0 Arteriovenous fistula, acquired
0.515 0.485 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.515 0.485 0.000
E28.3 Primary ovarian failure
0.513 0.486 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.511 0.489 0.000
I11 Hypertensive heart disease
0.509 0.491 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.509 0.491 0.000
E23.1 Drug-induced hypopituitarism
0.509 0.491 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.505 0.494 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.505 0.494 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.505 0.494 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.505 0.494 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.505 0.494 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.505 0.494 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.505 0.494 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.505 0.494 0.000
E27.5 Adrenomedullary hyperfunction
0.504 0.495 0.000
E27.0 Other adrenocortical overactivity
0.504 0.495 0.000
I70.1 Atherosclerosis of renal artery
0.503 0.497 0.000
I70.9 Generalised and unspecified atherosclerosis
0.502 0.498 0.000
C80.9 Malignant neoplasm, unspecified
0.000 0.500 0.500
E20.8 Other hypoparathyroidism
0.499 0.501 0.000
E20.0 Idiopathic hypoparathyroidism
0.499 0.501 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.496 0.504 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.495 0.505 0.000
I70.8 Atherosclerosis of other arteries
0.494 0.505 0.000
I07.9 Tricuspid valve disease, unspecified
0.493 0.506 0.000
I07.8 Other tricuspid valve diseases
0.493 0.506 0.000
I07.2 Tricuspid stenosis with insufficiency
0.493 0.506 0.000
I07.0 Tricuspid stenosis
0.493 0.506 0.000
I15.9 Seconday hypertension, unspecified
0.486 0.514 0.000
I09 Other rheumatic heart diseases
0.483 0.517 0.000
I78 Diseases of capillaries
0.482 0.517 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.482 0.518 0.000
I51.7 Cardiomegaly
0.482 0.518 0.000
I37.0 Pulmonary valve stenosis
0.481 0.518 0.000
E61 Deficiency of other nutrient elements
0.478 0.522 0.000
I28.8 Other specified diseases of pulmonary vessels
0.477 0.523 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.477 0.523 0.000
Chapter II Neoplasms
0.000 0.525 0.475
K90.0 Coeliac disease
0.473 0.527 0.000
I06.0 Rheumatic aortic stenosis
0.472 0.528 0.000
T82.1 Mechanical complication of cardiac electronic device
0.471 0.529 0.000
I42.6 Alcoholic cardiomyopathy
0.469 0.531 0.000
E29 Testicular dysfunction
0.469 0.531 0.000
E12.9 Without complications
0.469 0.531 0.000
E12.8 With unspecified complications
0.469 0.531 0.000
E12.7 With multiple complications
0.469 0.531 0.000
E12.6 With other specified complications
0.469 0.531 0.000
E12.5 With peripheral circulatory complications
0.469 0.531 0.000
E12.4 With neurological complications
0.469 0.531 0.000
E12.3 With ophthalmic complications
0.469 0.531 0.000
E12.2 With renal complications
0.469 0.531 0.000
E12.1 With ketoacidosis
0.469 0.531 0.000
E12.0 With coma
0.469 0.531 0.000
I71 Aortic aneurysm and dissection
0.468 0.532 0.000
I30.8 Other forms of acute pericarditis
0.468 0.532 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.468 0.532 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.467 0.533 0.000
C79.2 Secondary malignant neoplasm of skin
0.000 0.534 0.466
I31.0 Chronic adhesive pericarditis
0.465 0.535 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.460 0.540 0.000
E58 Dietary calcium deficiency
0.460 0.540 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.456 0.544 0.000
I06.8 Other rheumatic aortic valve diseases
0.456 0.544 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.456 0.544 0.000
I06.1 Rheumatic aortic insufficiency
0.456 0.544 0.000
E31.0 Autoimmune polyglandular failure
0.456 0.544 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.000 0.544 0.455
E07.9 Disorder of thyroid, unspecified
0.454 0.546 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.454 0.546 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.454 0.546 0.000
E16.4 Abnormal secretion of gastrin
0.454 0.546 0.000
E16.3 Increased secretion of glucagon
0.454 0.546 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.452 0.547 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.452 0.547 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.452 0.547 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.452 0.547 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.452 0.547 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.452 0.547 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.452 0.547 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.452 0.547 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.452 0.547 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.452 0.547 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.452 0.547 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.452 0.547 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.452 0.547 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.452 0.547 0.000
I48.4 Atypical atrial flutter
0.452 0.547 0.000
I48.3 Typical atrial flutter
0.452 0.547 0.000
I48.2 Chronic atrial fibrillation
0.452 0.547 0.000
I48.1 Persistent atrial fibrillation
0.452 0.547 0.000
I48.0 Paroxysmal atrial fibrillation
0.452 0.547 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.452 0.547 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.452 0.547 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.452 0.547 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.452 0.548 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.452 0.548 0.000
E22.8 Other hyperfunction of pituitary gland
0.452 0.548 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.000 0.548 0.452
I02 Rheumatic chorea
0.451 0.548 0.000
I01 Rheumatic fever with heart involvement
0.451 0.548 0.000
I97.0 Postcardiotomy syndrome
0.451 0.549 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.451 0.549 0.000
I72.4 Aneurysm of artery of lower extremity
0.450 0.550 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.450 0.550 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.447 0.552 0.000
I08 Multiple valve diseases
0.447 0.553 0.000
I31.1 Chronic constrictive pericarditis
0.445 0.555 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.000 0.556 0.444
E34.0 Carcinoid syndrome
0.438 0.562 0.000
I78.8 Other diseases of capillaries
0.438 0.562 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.563 0.437
E27.9 Disorder of adrenal gland, unspecified
0.436 0.563 0.000
E28.9 Ovarian dysfunction, unspecified
0.433 0.567 0.000
E28.8 Other ovarian dysfunction
0.433 0.567 0.000
E28.1 Androgen excess
0.433 0.567 0.000
E28.0 Oestrogen excess
0.433 0.567 0.000
I40.8 Other acute myocarditis
0.432 0.568 0.000
I40.1 Isolated myocarditis
0.432 0.568 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.432 0.568 0.000
E31.9 Polyglandular dysfunction, unspecified
0.431 0.568 0.000
E31.8 Other polyglandular dysfunction
0.431 0.568 0.000
E31.1 Polyglandular hyperfunction
0.431 0.568 0.000
E25.9 Adrenogenital disorder, unspecified
0.429 0.571 0.000
E25.8 Other adrenogenital disorders
0.429 0.571 0.000
I40.9 Acute myocarditis, unspecified
0.429 0.571 0.000
E51 Thiamine deficiency
0.427 0.573 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.427 0.573 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.427 0.573 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.427 0.573 0.000
E13.3 With ophthalmic complications
0.425 0.575 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.424 0.575 0.000
E63 Other nutritional deficiencies
0.424 0.575 0.000
E50 Vitamin A deficiency
0.424 0.575 0.000
E60 Dietary zinc deficiency
0.424 0.575 0.000
E59 Dietary selenium deficiency
0.424 0.575 0.000
E54 Ascorbic acid deficiency
0.424 0.575 0.000
E52 Niacin deficiency [pellagra]
0.424 0.575 0.000
I72.8 Aneurysm of other specified arteries
0.424 0.575 0.000
I51.6 Cardiovascular disease, unspecified
0.422 0.578 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.000 0.578 0.422
E07.1 Dyshormogenetic goitre
0.421 0.578 0.000
E07.0 Hypersecretion of calcitonin
0.421 0.578 0.000
I72.2 Aneurysm of renal artery
0.418 0.582 0.000
E16.1 Other hypoglycaemia
0.418 0.582 0.000
I46.0 Cardiac arrest with successful resuscitation
0.417 0.583 0.000
T82.3 Mechanical complication of other vascular grafts
0.416 0.584 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.416 0.584 0.000
I42.5 Other restrictive cardiomyopathy
0.416 0.584 0.000
I42.4 Endocardial fibroelastosis
0.416 0.584 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.416 0.584 0.000
C51-C58 Malignant neoplasms of female genital organs
0.000 0.585 0.415
I20.0 Unstable angina
0.414 0.586 0.000
E30.9 Disorder of puberty, unspecified
0.414 0.586 0.000
E30.8 Other disorders of puberty
0.414 0.586 0.000
E30.1 Precocious puberty
0.414 0.586 0.000
E30.0 Delayed puberty
0.414 0.586 0.000
E32.9 Disease of thymus, unspecified
0.414 0.586 0.000
E32.8 Other diseases of thymus
0.414 0.586 0.000
E32.1 Abscess of thymus
0.414 0.586 0.000
E32.0 Persistent hyperplasia of thymus
0.414 0.586 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.414 0.586 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.414 0.586 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.414 0.586 0.000
E61.1 Iron deficiency
0.414 0.586 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.412 0.588 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.411 0.589 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.411 0.589 0.000
I98.0 Cardiovascular syphilis
0.411 0.589 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.000 0.590 0.410
I28.9 Disease of pulmonary vessels, unspecified
0.409 0.590 0.000
I28.1 Aneurysm of pulmonary artery
0.409 0.590 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.409 0.590 0.000
E34.9 Endocrine disorder, unspecified
0.408 0.592 0.000
E34.5 Androgen resistance syndrome
0.408 0.592 0.000
E34.4 Constitutional tall stature
0.408 0.592 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.408 0.592 0.000
E34.1 Other hypersecretion of intestinal hormones
0.408 0.592 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.408 0.592 0.000
I40.0 Infective myocarditis
0.406 0.593 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.404 0.596 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.404 0.596 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.403 0.596 0.000
C50.6 Axillary tail of breast
0.000 0.600 0.400
E56 Other vitamin deficiencies
0.400 0.600 0.000
I45 Other conduction disorders
0.399 0.601 0.000
I08.0 Disorders of both mitral and aortic valves
0.398 0.602 0.000
E13.8 With unspecified complications
0.397 0.602 0.000
E13.7 With multiple complications
0.397 0.602 0.000
E13.6 With other specified complications
0.397 0.602 0.000
E13.5 With peripheral circulatory complications
0.397 0.602 0.000
E13.4 With neurological complications
0.397 0.602 0.000
E13.2 With renal complications
0.397 0.602 0.000
E13.1 With ketoacidosis
0.397 0.602 0.000
E13.0 With coma
0.397 0.602 0.000
E24 Cushing's syndrome
0.397 0.603 0.000
E34.3 Short stature, not elsewhere classified
0.397 0.603 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.396 0.604 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.393 0.607 0.000
E45 Retarded development following protein-energy malnutrition
0.393 0.607 0.000
E43 Unspecified severe protein-energy malnutrition
0.393 0.607 0.000
E42 Marasmic kwashiorkor
0.393 0.607 0.000
E41 Nutritional marasmus
0.393 0.607 0.000
E40 Kwashiorkor
0.393 0.607 0.000
E26.8 Other hyperaldosteronism
0.392 0.608 0.000
E26.1 Secondary hyperaldosteronism
0.392 0.608 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.391 0.609 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.000 0.611 0.389
I70.0 Atherosclerosis of aorta
0.389 0.611 0.000
Z95.0 Presence of cardiac pacemaker
0.389 0.611 0.000
I31.8 Other specified diseases of pericardium
0.388 0.612 0.000
I31.2 Haemopericardium, not elsewhere classified
0.388 0.612 0.000
I30.9 Acute pericarditis, unspecified
0.387 0.613 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.386 0.614 0.000
E26.9 Hyperaldosteronism, unspecified
0.385 0.615 0.000
I05.9 Mitral valve disease, unspecified
0.385 0.615 0.000
I72.0 Aneurysm of carotid artery
0.383 0.617 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.383 0.617 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.000 0.618 0.382
C51 Malignant neoplasm of vulva
0.000 0.618 0.382
I72.1 Aneurysm of artery of upper extremity
0.382 0.618 0.000
I46.1 Sudden cardiac death, so described
0.376 0.624 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.375 0.625 0.000
E34.8 Other specified endocrine disorders
0.372 0.628 0.000
C79.6 Secondary malignant neoplasm of ovary
0.000 0.630 0.370
I51.2 Rupture of papillary muscle, not elsewhere classified
0.370 0.630 0.000
E26.0 Primary hyperaldosteronism
0.369 0.631 0.000
E53 Deficiency of other B group vitamins
0.365 0.634 0.000
I00 Rheumatic fever without mention of heart involvement
0.364 0.636 0.001
I70.11 Atherosclerosis of renal artery (with gangrene)
0.360 0.639 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.360 0.640 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.358 0.641 0.000
C51.9 Vulva, unspecified
0.000 0.642 0.358
I70.10 Atherosclerosis of renal artery (without gangrene)
0.357 0.643 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.000 0.644 0.356
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.355 0.644 0.000
I97.1 Other functional disturbances following cardiac surgery
0.355 0.645 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.355 0.645 0.000
I50 Heart failure
0.353 0.647 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.352 0.648 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.350 0.650 0.000
I51.0 Cardiac septal defect, acquired
0.347 0.653 0.000
I45.4 Nonspecific intraventricular block
0.347 0.653 0.000
I09.8 Other specified rheumatic heart diseases
0.346 0.653 0.000
I09.2 Chronic rheumatic pericarditis
0.346 0.653 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.346 0.653 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.