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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0174
log Bayes Factor = 214.209
contains 8 variants:
rs114495629
lBF = 14.504
Chr 1 : 245,701,098
rs74726954
lBF = 15.819
Chr 5 : 88,738,190
rs16889916
lBF = 20.776
Chr 6 : 24,989,384
rs74349534
lBF = 15.551
Chr 7 : 83,764,113
rs117593677
lBF = 14.711
Chr 9 : 21,318,205
rs73045775
lBF = 23.386
Chr12 : 8,674,905
rs76246633
lBF = 27.275
Chr16 : 74,924,716
rs61754763
lBF = 16.219
Chr20 : 5,966,763
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
I25.8 Other forms of chronic ischaemic heart disease
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
O60-O75 Complications of labour and delivery
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Z00-Z13 Persons encountering health services for examination and investigation
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
1.000 0.000 0.000
Z92 Personal history of medical treatment
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I21 Acute myocardial infarction
1.000 0.000 0.000
Z95.5 Presence of coronary angioplasty implant and graft
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
Z88.1 Personal history of allergy to other antibiotic agents
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
T66-T78 Other and unspecified effects of external causes
0.999 0.001 0.000
F30-F39 Mood [affective] disorders
0.999 0.001 0.000
I45 Other conduction disorders
0.999 0.001 0.000
Z96 Presence of other functional implants
0.999 0.001 0.000
Z96.1 Presence of intraocular lens
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.999 0.001 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.999 0.001 0.000
I20.0 Unstable angina
0.999 0.001 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.999 0.001 0.000
I80 Phlebitis and thrombophlebitis
0.999 0.001 0.000
S80-S89 Injuries to the knee and lower leg
0.999 0.001 0.000
H55-H59 Other disorders of eye and adnexa
0.999 0.001 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.998 0.002 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.998 0.002 0.000
Z94 Transplanted organ and tissue status
0.998 0.002 0.000
T78 Adverse effects, not elsewhere classified
0.998 0.002 0.000
M13 Other arthritis
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.997 0.003 0.000
G90-G99 Other disorders of the nervous system
0.997 0.003 0.000
Chapter VIII Diseases of the ear and mastoid process
0.997 0.003 0.000
I05-I09 Chronic rheumatic heart diseases
0.997 0.003 0.000
M45-M49 Spondylopathies
0.997 0.003 0.000
Z13 Special screening examination for other diseases and disorders
0.996 0.004 0.000
M13.9 Arthritis, unspecified
0.996 0.004 0.000
I44 Atrioventricular and left bundle-branch block
0.996 0.004 0.000
O70 Perineal laceration during delivery
0.996 0.004 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.996 0.004 0.000
E20-E35 Disorders of other endocrine glands
0.996 0.004 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.996 0.004 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.996 0.004 0.000
Z34 Supervision of normal pregnancy
0.996 0.004 0.000
M70-M79 Other soft tissue disorders
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.996 0.004 0.000
Z95.0 Presence of cardiac pacemaker
0.996 0.004 0.000
J95-J99 Other diseases of the respiratory system
0.995 0.005 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.995 0.005 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.995 0.005 0.000
H57 Other disorders of eye and adnexa
0.995 0.005 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
I86 Varicose veins of other sites
0.995 0.005 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.995 0.005 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.995 0.005 0.000
C15-C26 Malignant neoplasms of digestive organs
0.995 0.005 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.995 0.005 0.000
S60-S69 Injuries to the wrist and hand
0.995 0.005 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.994 0.006 0.000
O70.0 First degree perineal laceration during delivery
0.994 0.006 0.000
H36 Retinal disorders in diseases classified elsewhere
0.994 0.006 0.000
I24 Other acute ischaemic heart diseases
0.993 0.007 0.000
Y52 Agents primarily affecting the cardiovascular system
0.993 0.007 0.000
I21.9 Acute myocardial infarction, unspecified
0.993 0.007 0.000
M35 Other systemic involvement of connective tissue
0.993 0.007 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.993 0.007 0.000
S70-S79 Injuries to the hip and thigh
0.993 0.007 0.000
I44.0 Atrioventricular block, first degree
0.992 0.008 0.000
I51 Complications and ill-defined descriptions of heart disease
0.992 0.008 0.000
N17-N19 Renal failure
0.992 0.008 0.000
D10-D36 Benign neoplasms
0.992 0.008 0.000
C18 Malignant neoplasm of colon
0.992 0.008 0.000
N18 Chronic renal failure
0.991 0.009 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.991 0.009 0.000
Z04 Examination and observation for other reasons
0.991 0.009 0.000
Z94.8 Other transplanted organ and tissue status
0.991 0.009 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.990 0.010 0.000
I22 Subsequent myocardial infarction
0.990 0.010 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.990 0.010 0.000
Z98 Other postsurgical states
0.990 0.010 0.000
H65-H75 Diseases of middle ear and mastoid
0.989 0.011 0.000
C64-C68 Malignant neoplasms of urinary tract
0.989 0.011 0.000
H36.0 Diabetic retinopathy
0.989 0.011 0.000
M35.3 Polymyalgia rheumatica
0.989 0.011 0.000
S20-S29 Injuries to the thorax
0.989 0.011 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.989 0.011 0.000
Z88.2 Personal history of allergy to sulphonamides
0.988 0.012 0.000
H53-H54 Visual disturbances and blindness
0.988 0.012 0.000
J98 Other respiratory disorders
0.988 0.012 0.000
M25.4 Effusion of joint
0.988 0.012 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.988 0.012 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.988 0.012 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.987 0.013 0.000
F32 Depressive episode
0.987 0.013 0.000
T78.4 Allergy, unspecified
0.986 0.014 0.000
C67 Malignant neoplasm of bladder
0.986 0.014 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.986 0.014 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.986 0.014 0.000
G93 Other disorders of brain
0.985 0.015 0.000
N60-N64 Disorders of breast
0.985 0.015 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.985 0.015 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.985 0.015 0.000
H54 Blindness and low vision
0.984 0.016 0.000
Z45 Adjustment and management of implanted device
0.983 0.017 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.982 0.018 0.000
O16 Unspecified maternal hypertension
0.981 0.019 0.000
I42 Cardiomyopathy
0.981 0.019 0.000
E10.3 With ophthalmic complications
0.981 0.019 0.000
F31 Bipolar affective disorder
0.981 0.019 0.000
M47 Spondylosis
0.980 0.020 0.000
S72 Fracture of femur
0.980 0.020 0.000
I51.8 Other ill-defined heart diseases
0.980 0.020 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.980 0.020 0.000
N60 Benign mammary dysplasia
0.980 0.020 0.000
I86.1 Scrotal varices
0.979 0.021 0.000
I71 Aortic aneurysm and dissection
0.979 0.021 0.000
S81 Open wound of lower leg
0.979 0.021 0.000
M25.46 Effusion of joint (Lower leg)
0.979 0.021 0.000
C92 Myeloid leukaemia
0.979 0.021 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.979 0.021 0.000
D69 Purpura and other haemorrhagic conditions
0.979 0.021 0.000
Z34.0 Supervision of normal first pregnancy
0.978 0.022 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.978 0.022 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.977 0.023 0.000
J00-J06 Acute upper respiratory infections
0.977 0.023 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.977 0.023 0.000
Z95.2 Presence of prosthetic heart valve
0.977 0.023 0.000
Z45.2 Adjustment and management of vascular access device
0.977 0.023 0.000
Z35 Supervision of high-risk pregnancy
0.977 0.023 0.000
I24.8 Other forms of acute ischaemic heart disease
0.976 0.024 0.000
M79.8 Other specified soft tissue disorders
0.975 0.025 0.000
I08 Multiple valve diseases
0.975 0.025 0.000
D00-D09 In situ neoplasms
0.975 0.025 0.000
M47.9 Spondylosis, unspecified
0.975 0.025 0.000
M25.7 Osteophyte
0.974 0.026 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.973 0.027 0.000
C90.0 Multiple myeloma
0.971 0.029 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.971 0.029 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.971 0.029 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.970 0.030 0.000
N00-N08 Glomerular diseases
0.970 0.030 0.000
Y57 Other and unspecified drugs and medicaments
0.969 0.031 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.969 0.031 0.000
A00-A09 Intestinal infectious diseases
0.969 0.031 0.000
M24 Other specific joint derangements
0.968 0.032 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.968 0.032 0.000
Z04.1 Examination and observation following transport accident
0.968 0.032 0.000
N18.3 Chronic kidney disease, stage 3
0.968 0.032 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.968 0.032 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.968 0.032 0.000
Z95.1 Presence of aortocoronary bypass graft
0.967 0.033 0.000
I05 Rheumatic mitral valve diseases
0.967 0.033 0.000
H35 Other retinal disorders
0.967 0.033 0.000
C18.9 Colon, unspecified
0.967 0.033 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.966 0.034 0.000
I50 Heart failure
0.966 0.034 0.000
H57.8 Other specified disorders of eye and adnexa
0.966 0.034 0.000
Z95.4 Presence of other heart-valve replacement
0.966 0.034 0.000
I47 Paroxysmal tachycardia
0.966 0.034 0.000
E11.3 With ophthalmic complications
0.966 0.034 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.965 0.035 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.964 0.036 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.963 0.037 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.962 0.038 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.962 0.038 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.961 0.039 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.961 0.039 0.000
Chapter XXII Codes for special purposes
0.960 0.040 0.000
I45.1 Other and unspecified right bundle-branch block
0.960 0.040 0.000
N60.1 Diffuse cystic mastopathy
0.959 0.041 0.000
S40-S49 Injuries to the shoulder and upper arm
0.958 0.042 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.957 0.043 0.000
Z98.8 Other specified postsurgical states
0.957 0.043 0.000
I25.5 Ischaemic cardiomyopathy
0.956 0.044 0.000
I47.1 Supraventricular tachycardia
0.956 0.044 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.956 0.044 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.956 0.044 0.000
Z89 Acquired absence of limb
0.954 0.046 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.952 0.048 0.000
N10-N16 Renal tubulo-interstitial diseases
0.951 0.049 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.951 0.049 0.000
J09-J18 Influenza and pneumonia
0.951 0.049 0.000
I45.5 Other specified heart block
0.950 0.050 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.950 0.050 0.000
O72 Postpartum haemorrhage
0.950 0.050 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.949 0.051 0.000
D75 Other diseases of blood and blood-forming organs
0.949 0.051 0.000
Z63 Other problems related to primary support group, including family circumstances
0.949 0.051 0.000
J84 Other interstitial pulmonary diseases
0.949 0.051 0.000
I70 Atherosclerosis
0.949 0.051 0.000
D46 Myelodysplastic syndromes
0.949 0.051 0.000
Z88.5 Personal history of allergy to narcotic agent
0.949 0.051 0.000
J98.1 Pulmonary collapse
0.948 0.052 0.000
Z80 Family history of malignant neoplasm
0.948 0.052 0.000
S81.0 Open wound of knee
0.948 0.052 0.000
H57.1 Ocular pain
0.948 0.052 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.948 0.052 0.000
Z71.8 Other specified counselling
0.947 0.053 0.000
I10-I15 Hypertensive diseases
0.947 0.053 0.000
W00-W19 Falls
0.946 0.054 0.000
N18.5 Chronic kidney disease, stage 5
0.946 0.054 0.000
I45.9 Conduction disorder, unspecified
0.946 0.054 0.000
T90 Sequelae of injuries of head
0.945 0.055 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.945 0.055 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.944 0.056 0.000
Z57 Occupational exposure to risk-factors
0.943 0.057 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.943 0.057 0.000
C67.9 Bladder, unspecified
0.943 0.057 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.942 0.058 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.941 0.059 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.941 0.059 0.000
D24 Benign neoplasm of breast
0.941 0.059 0.000
Y57.9 Drug or medicament, unspecified
0.941 0.059 0.000
Z97 Presence of other devices
0.941 0.059 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.940 0.060 0.000
E11.2 With renal complications
0.940 0.060 0.000
C18.6 Descending colon
0.940 0.060 0.000
G93.6 Cerebral oedema
0.940 0.060 0.000
Z95.3 Presence of xenogenic heart valve
0.939 0.061 0.000
M23 Internal derangement of knee
0.939 0.061 0.000
C67.4 Posterior wall of bladder
0.938 0.062 0.000
M46 Other inflammatory spondylopathies
0.938 0.062 0.000
I82 Other venous embolism and thrombosis
0.938 0.062 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.937 0.063 0.000
E10.1 With ketoacidosis
0.937 0.063 0.000
Q50-Q56 Congenital malformations of genital organs
0.936 0.063 0.000
J03 Acute tonsillitis
0.935 0.065 0.000
G58 Other mononeuropathies
0.935 0.065 0.000
Z49 Care involving dialysis
0.934 0.066 0.000
D68 Other coagulation defects
0.933 0.067 0.000
G95 Other diseases of spinal cord
0.933 0.067 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.933 0.067 0.000
E70-E90 Metabolic disorders
0.933 0.067 0.000
Y40 Systemic antibiotics
0.933 0.067 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.932 0.068 0.000
Z85 Personal history of malignant neoplasm
0.932 0.068 0.000
Z43 Attention to artificial openings
0.932 0.068 0.000
N99-N99 Other disorders of the genitourinary system
0.931 0.069 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.931 0.069 0.000
D41.0 Kidney
0.931 0.069 0.000
Z40 Prophylactic surgery
0.930 0.070 0.000
S20 Superficial injury of thorax
0.930 0.070 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.930 0.070 0.000
M15-M19 Arthrosis
0.930 0.070 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.929 0.071 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.929 0.071 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.928 0.072 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.927 0.073 0.000
Z36 Antenatal screening
0.927 0.073 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.927 0.073 0.000
D41.4 Bladder
0.927 0.073 0.000
I12 Hypertensive renal disease
0.927 0.073 0.000
H60-H62 Diseases of external ear
0.927 0.073 0.000
C92.0 Acute myeloid leukaemia
0.927 0.073 0.000
C32 Malignant neoplasm of larynx
0.926 0.074 0.000
H49 Paralytic strabismus
0.926 0.074 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.926 0.074 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.925 0.075 0.000
M19 Other arthrosis
0.925 0.075 0.000
I22.8 Subsequent myocardial infarction of other sites
0.925 0.075 0.000
D69.6 Thrombocytopenia, unspecified
0.925 0.075 0.000
D04 Carcinoma in situ of skin
0.925 0.075 0.000
H54.7 Unspecified visual loss
0.924 0.076 0.000
H52 Disorders of refraction and accommodation
0.924 0.076 0.000
M25.74 Osteophyte (Hand)
0.924 0.076 0.000
H54.9 Unspecified visual impairment (binocular)
0.924 0.076 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.924 0.076 0.000
Q60-Q64 Congenital malformations of the urinary system
0.923 0.077 0.000
V20-V29 Motorcycle rider injured in transport accident
0.922 0.078 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.922 0.078 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.922 0.078 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.919 0.081 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.919 0.081 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.919 0.081 0.000
Z12 Special screening examination for neoplasms
0.918 0.082 0.000
O46.9 Antepartum haemorrhage, unspecified
0.918 0.082 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.917 0.083 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.916 0.084 0.000
M19.9 Arthrosis, unspecified
0.916 0.084 0.000
F80-F89 Disorders of psychological development
0.915 0.085 0.000
M80-M85 Disorders of bone density and structure
0.915 0.085 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.914 0.086 0.000
E10.5 With peripheral circulatory complications
0.913 0.087 0.000
D10 Benign neoplasm of mouth and pharynx
0.913 0.087 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.913 0.087 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.911 0.089 0.000
H66 Suppurative and unspecified otitis media
0.911 0.089 0.000
N60.0 Solitary cyst of breast
0.911 0.089 0.000
S82 Fracture of lower leg, including ankle
0.910 0.090 0.000
G93.9 Disorder of brain, unspecified
0.909 0.091 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.909 0.091 0.000
T68 Hypothermia
0.908 0.092 0.000
H10-H13 Disorders of conjunctiva
0.908 0.092 0.000
I51.7 Cardiomegaly
0.907 0.093 0.000
C18.4 Transverse colon
0.907 0.093 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.907 0.093 0.000
G62 Other polyneuropathies
0.907 0.093 0.000
M25.72 Osteophyte (Upper arm)
0.906 0.094 0.000
I05.9 Mitral valve disease, unspecified
0.906 0.094 0.000
D47.1 Chronic myeloproliferative disease
0.906 0.094 0.000
Z29 Need for other prophylactic measures
0.906 0.094 0.000
A30-A49 Other bacterial diseases
0.906 0.094 0.000
O20 Haemorrhage in early pregnancy
0.906 0.094 0.000
I50.1 Left ventricular failure
0.906 0.094 0.000
D75.1 Secondary polycythaemia
0.905 0.095 0.000
C92.1 Chronic myeloid leukaemia
0.905 0.095 0.000
N10 Acute tubulo-interstitial nephritis
0.905 0.095 0.000
J03.9 Acute tonsillitis, unspecified
0.904 0.096 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.904 0.096 0.000
D09 Carcinoma in situ of other and unspecified sites
0.904 0.096 0.000
M71 Other bursopathies
0.903 0.097 0.000
C91 Lymphoid leukaemia
0.903 0.097 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.903 0.097 0.000
I72 Other aneurysm
0.903 0.097 0.000
I50.0 Congestive heart failure
0.903 0.097 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.902 0.098 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.902 0.098 0.000
E10.4 With neurological complications
0.902 0.098 0.000
I99 Other and unspecified disorders of circulatory system
0.902 0.098 0.000
H74 Other disorders of middle ear and mastoid
0.902 0.098 0.000
E13 Other specified diabetes mellitus
0.901 0.098 0.000
Z94.0 Kidney transplant status
0.901 0.099 0.000
I86.4 Gastric varices
0.901 0.099 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.901 0.099 0.000
C69 Malignant neoplasm of eye and adnexa
0.901 0.099 0.000
G58.8 Other specified mononeuropathies
0.900 0.100 0.000
M19.94 Arthrosis, unspecified (Hand)
0.900 0.100 0.000
Z46 Fitting and adjustment of other devices
0.900 0.100 0.000
D48.5 Skin
0.900 0.100 0.000
M91-M94 Chondropathies
0.900 0.100 0.000
H55 Nystagmus and other irregular eye movements
0.899 0.101 0.000
O30 Multiple gestation
0.898 0.102 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.898 0.102 0.000
E27 Other disorders of adrenal gland
0.898 0.102 0.000
O23 Infections of genito-urinary tract in pregnancy
0.897 0.103 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.897 0.103 0.000
H72 Perforation of tympanic membrane
0.897 0.103 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.897 0.103 0.000
M60-M63 Disorders of muscles
0.897 0.103 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.896 0.104 0.000
W20-W49 Exposure to inanimate mechanical forces
0.896 0.104 0.000
E11.1 With ketoacidosis
0.896 0.104 0.000
D80-D89 Certain disorders involving the immune mechanism
0.895 0.105 0.000
Y45.0 Opioids and related analgesics
0.895 0.105 0.000
D26 Other benign neoplasms of uterus
0.895 0.105 0.000
Z43.2 Attention to ileostomy
0.894 0.106 0.000
N18.4 Chronic kidney disease, stage 4
0.894 0.106 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.893 0.107 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.893 0.107 0.000
A80-A89 Viral infections of the central nervous system
0.892 0.108 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.892 0.108 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.891 0.109 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.891 0.109 0.000
H35.0 Background retinopathy and retinal vascular changes
0.891 0.109 0.000
M79.1 Myalgia
0.891 0.109 0.000
C71 Malignant neoplasm of brain
0.889 0.111 0.000
S29 Other and unspecified injuries of thorax
0.889 0.111 0.000
Z39 Postpartum care and examination
0.889 0.111 0.000
D35.1 Parathyroid gland
0.888 0.112 0.000
S72.1 Pertrochanteric fracture
0.888 0.112 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.888 0.112 0.000
Z45.1 Adjustment and management of infusion pump
0.888 0.112 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.887 0.113 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.887 0.113 0.000
M25.71 Osteophyte (Shoulder region)
0.887 0.113 0.000
E11.5 With peripheral circulatory complications
0.886 0.114 0.000
I87 Other disorders of veins
0.886 0.114 0.000
G70-G73 Diseases of myoneural junction and muscle
0.886 0.114 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.886 0.114 0.000
H35.7 Separation of retinal layers
0.886 0.114 0.000
J81 Pulmonary oedema
0.885 0.115 0.000
Z71.3 Dietary counselling and surveillance
0.885 0.115 0.000
S00-S09 Injuries to the head
0.885 0.115 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.885 0.115 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.885 0.115 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.884 0.116 0.000
C32.0 Glottis
0.884 0.116 0.000
N18.2 Chronic kidney disease, stage 2
0.883 0.117 0.000
I42.0 Dilated cardiomyopathy
0.883 0.117 0.000
S69 Other and unspecified injuries of wrist and hand
0.883 0.117 0.000
Y45.1 Salicylates
0.883 0.117 0.000
O85-O92 Complications predominantly related to the puerperium
0.883 0.117 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.883 0.117 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.883 0.117 0.000
I46 Cardiac arrest
0.882 0.118 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.882 0.118 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.882 0.118 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.882 0.118 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.881 0.119 0.000
E23 Hypofunction and other disorders of pituitary gland
0.881 0.119 0.000
D45 Polycythaemia vera
0.881 0.119 0.000
F31.9 Bipolar affective disorder, unspecified
0.880 0.120 0.000
S40 Superficial injury of shoulder and upper arm
0.880 0.120 0.000
Z11.2 Special screening examination for other bacterial diseases
0.879 0.121 0.000
H50 Other strabismus
0.879 0.121 0.000
I45.6 Preexcitation syndrome
0.879 0.121 0.000
Z04.8 Examination and observation for other specified reasons
0.878 0.122 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.878 0.122 0.000
H61 Other disorders of external ear
0.876 0.124 0.000
H66.3 Other chronic suppurative otitis media
0.876 0.124 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.876 0.124 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.875 0.125 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.875 0.125 0.000
F43 Reaction to severe stress, and adjustment disorders
0.874 0.126 0.000
O26.9 Pregnancy-related condition, unspecified
0.874 0.126 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.874 0.126 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.874 0.126 0.000
O66 Other obstructed labour
0.872 0.127 0.000
S72.0 Fracture of neck of femur
0.872 0.128 0.000
S72.2 Subtrochanteric fracture
0.872 0.128 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.872 0.128 0.000
I12.9 Hypertensive renal disease without renal failure
0.872 0.128 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.872 0.128 0.000
Z49.0 Preparatory care for dialysis
0.871 0.129 0.000
Z13.1 Special screening examination for diabetes mellitus
0.871 0.129 0.000
Z60 Problems related to social environment
0.871 0.129 0.000
M23.4 Loose body in knee
0.871 0.129 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.870 0.130 0.000
H43-H45 Disorders of vitreous body and globe
0.870 0.130 0.000
O62 Abnormalities of forces of labour
0.870 0.130 0.000
M65-M68 Disorders of synovium and tendon
0.869 0.131 0.000
I81 Portal vein thrombosis
0.869 0.131 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.868 0.132 0.000
I34 Nonrheumatic mitral valve disorders
0.868 0.132 0.000
Y40.0 Penicillins
0.868 0.132 0.000
E14 Unspecified diabetes mellitus
0.868 0.132 0.000
I44.6 Other and unspecified fascicular block
0.868 0.132 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.866 0.134 0.000
S82.2 Fracture of shaft of tibia
0.866 0.134 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.866 0.134 0.000
M11 Other crystal arthropathies
0.866 0.134 0.000
I44.1 Atrioventricular block, second degree
0.865 0.135 0.000
L20-L30 Dermatitis and eczema
0.865 0.135 0.000
Z63.4 Disappearance and death of family member
0.865 0.135 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.865 0.135 0.000
Z89.5 Acquired absence of leg at or below knee
0.864 0.136 0.000
S70 Superficial injury of hip and thigh
0.864 0.136 0.000
Y43 Primarily systemic agents
0.864 0.136 0.000
C51-C58 Malignant neoplasms of female genital organs
0.864 0.136 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.864 0.136 0.000
F32.1 Moderate depressive episode
0.863 0.137 0.000
D34 Benign neoplasm of thyroid gland
0.863 0.137 0.000
G58.9 Mononeuropathy, unspecified
0.863 0.137 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.862 0.138 0.000
E40-E46 Malnutrition
0.862 0.138 0.000
M24.1 Other articular cartilage disorders
0.861 0.139 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.861 0.139 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.861 0.139 0.000
Z98.0 Intestinal bypass and anastomosis status
0.861 0.139 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.860 0.140 0.000
O40 Polyhydramnios
0.860 0.140 0.000
N13 Obstructive and reflux uropathy
0.860 0.140 0.000
I42.8 Other cardiomyopathies
0.858 0.142 0.000
D72 Other disorders of white blood cells
0.858 0.142 0.000
T93 Sequelae of injuries of lower limb
0.858 0.142 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.857 0.143 0.000
I12.0 Hypertensive renal disease with renal failure
0.857 0.143 0.000
Z33 Pregnant state, incidental
0.857 0.143 0.000
T92 Sequelae of injuries of upper limb
0.857 0.143 0.000
E83 Disorders of mineral metabolism
0.857 0.143 0.000
O21 Excessive vomiting in pregnancy
0.857 0.143 0.000
I82.8 Embolism and thrombosis of other specified veins
0.857 0.143 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.856 0.144 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.856 0.144 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.856 0.144 0.000
H54.0 Blindness, both eyes
0.855 0.145 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.855 0.145 0.000
D68.8 Other specified coagulation defects
0.855 0.145 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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