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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114495629
log Bayes Factor = 14.5035
Chromosome 1   position 245,701,098  (GRCh37) Explore rs114495629 on Ensembl!
Variant rs114495629 is part of Cluster X0174

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.988 0.012 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.984 0.016 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
D10-D36 Benign neoplasms
0.978 0.022 0.000
Z92 Personal history of medical treatment
0.975 0.025 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.972 0.028 0.000
I50 Heart failure
0.970 0.030 0.000
Chapter X Diseases of the respiratory system
0.969 0.031 0.000
I45 Other conduction disorders
0.959 0.041 0.000
M20-M25 Other joint disorders
0.956 0.044 0.000
C51-C58 Malignant neoplasms of female genital organs
0.955 0.045 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.954 0.046 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.952 0.048 0.000
Chapter XI Diseases of the digestive system
0.951 0.049 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.950 0.050 0.000
Chapter V Mental and behavioural disorders
0.950 0.050 0.000
O60-O75 Complications of labour and delivery
0.949 0.051 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.947 0.053 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.943 0.057 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.941 0.059 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.938 0.062 0.000
Z95.1 Presence of aortocoronary bypass graft
0.933 0.067 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.931 0.069 0.000
J40-J47 Chronic lower respiratory diseases
0.931 0.069 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.923 0.077 0.000
I51 Complications and ill-defined descriptions of heart disease
0.922 0.078 0.000
K01 Embedded and impacted teeth
0.921 0.079 0.000
M23 Internal derangement of knee
0.919 0.081 0.000
Chapter VII Diseases of the eye and adnexa
0.917 0.083 0.000
O00-O08 Pregnancy with abortive outcome
0.913 0.087 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.913 0.087 0.000
I05-I09 Chronic rheumatic heart diseases
0.911 0.089 0.000
D27 Benign neoplasm of ovary
0.907 0.093 0.000
T39.1 4-Aminophenol derivatives
0.905 0.095 0.000
J47 Bronchiectasis
0.904 0.096 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.902 0.098 0.000
K01.1 Impacted teeth
0.900 0.100 0.000
M15-M19 Arthrosis
0.898 0.102 0.000
C56 Malignant neoplasm of ovary
0.893 0.107 0.000
D17 Benign lipomatous neoplasm
0.892 0.108 0.000
K14 Diseases of tongue
0.892 0.108 0.000
K50-K52 Noninfective enteritis and colitis
0.892 0.108 0.000
I20-I25 Ischaemic heart diseases
0.889 0.111 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.889 0.111 0.000
F30-F39 Mood [affective] disorders
0.888 0.112 0.000
I50.9 Heart failure, unspecified
0.884 0.116 0.000
I80 Phlebitis and thrombophlebitis
0.880 0.120 0.000
Z37 Outcome of delivery
0.878 0.122 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.877 0.123 0.000
I50.1 Left ventricular failure
0.869 0.131 0.000
I44 Atrioventricular and left bundle-branch block
0.867 0.133 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.866 0.134 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.865 0.135 0.000
M45-M49 Spondylopathies
0.864 0.136 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.858 0.142 0.000
I45.1 Other and unspecified right bundle-branch block
0.856 0.144 0.000
D32 Benign neoplasm of meninges
0.856 0.144 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.855 0.145 0.000
M25 Other joint disorders, not elsewhere classified
0.854 0.146 0.000
I45.5 Other specified heart block
0.847 0.153 0.000
I08 Multiple valve diseases
0.847 0.153 0.000
I51.7 Cardiomegaly
0.846 0.154 0.000
M16 Coxarthrosis [arthrosis of hip]
0.845 0.155 0.000
T66-T78 Other and unspecified effects of external causes
0.844 0.156 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.843 0.157 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.843 0.157 0.000
T43.2 Other and unspecified antidepressants
0.841 0.159 0.000
Y43 Primarily systemic agents
0.840 0.160 0.000
I35 Nonrheumatic aortic valve disorders
0.838 0.162 0.000
J09-J18 Influenza and pneumonia
0.837 0.163 0.000
Z95.3 Presence of xenogenic heart valve
0.833 0.167 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.830 0.170 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.829 0.171 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.827 0.173 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.826 0.174 0.000
Z95.0 Presence of cardiac pacemaker
0.822 0.178 0.000
K02 Dental caries
0.821 0.179 0.000
S80-S89 Injuries to the knee and lower leg
0.818 0.182 0.000
Z37.0 Single live birth
0.817 0.183 0.000
K51 Ulcerative colitis
0.816 0.184 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.815 0.185 0.000
I60-I69 Cerebrovascular diseases
0.814 0.186 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.813 0.187 0.000
Z87 Personal history of other diseases and conditions
0.811 0.189 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.811 0.189 0.000
I34 Nonrheumatic mitral valve disorders
0.809 0.191 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.808 0.192 0.000
K14.8 Other diseases of tongue
0.808 0.192 0.000
I20 Angina pectoris
0.806 0.194 0.000
Y52 Agents primarily affecting the cardiovascular system
0.804 0.195 0.000
M23.8 Other internal derangements of knee
0.803 0.197 0.000
C79 Secondary malignant neoplasm of other sites
0.801 0.199 0.000
O70 Perineal laceration during delivery
0.800 0.200 0.000
O72 Postpartum haemorrhage
0.798 0.202 0.000
Z94 Transplanted organ and tissue status
0.797 0.203 0.000
O03 Spontaneous abortion
0.797 0.203 0.000
I49 Other cardiac arrhythmias
0.796 0.204 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.795 0.205 0.000
Z35 Supervision of high-risk pregnancy
0.794 0.206 0.000
K05 Gingivitis and periodontal diseases
0.793 0.207 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.793 0.207 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.792 0.208 0.000
O36 Maternal care for other known or suspected foetal problems
0.789 0.210 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.787 0.213 0.000
Z60 Problems related to social environment
0.787 0.213 0.000
D00-D09 In situ neoplasms
0.787 0.213 0.000
F32 Depressive episode
0.786 0.214 0.000
M16.9 Coxarthrosis, unspecified
0.785 0.215 0.000
D22 Melanocytic naevi
0.785 0.215 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.784 0.216 0.000
I50.0 Congestive heart failure
0.781 0.219 0.000
I46 Cardiac arrest
0.779 0.220 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.778 0.222 0.000
V20-V29 Motorcycle rider injured in transport accident
0.777 0.223 0.000
J95-J99 Other diseases of the respiratory system
0.777 0.223 0.000
M25.7 Osteophyte
0.776 0.224 0.000
K50 Crohn's disease [regional enteritis]
0.775 0.225 0.000
S60-S69 Injuries to the wrist and hand
0.774 0.226 0.000
L20-L30 Dermatitis and eczema
0.773 0.227 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.773 0.227 0.000
I45.9 Conduction disorder, unspecified
0.772 0.228 0.000
I20.8 Other forms of angina pectoris
0.771 0.229 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.770 0.230 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.770 0.230 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.770 0.230 0.000
J60-J70 Lung diseases due to external agents
0.766 0.234 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.766 0.234 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.765 0.235 0.000
K14.9 Disease of tongue, unspecified
0.765 0.235 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.765 0.235 0.000
M91-M94 Chondropathies
0.765 0.235 0.000
C78.2 Secondary malignant neoplasm of pleura
0.764 0.235 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.764 0.236 0.000
I33 Acute and subacute endocarditis
0.764 0.236 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.763 0.237 0.000
K04 Diseases of pulp and periapical tissues
0.762 0.238 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.761 0.238 0.000
Y43.3 Other antineoplastic drugs
0.759 0.241 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.759 0.241 0.000
D26 Other benign neoplasms of uterus
0.758 0.242 0.000
W20-W49 Exposure to inanimate mechanical forces
0.756 0.244 0.000
I08.0 Disorders of both mitral and aortic valves
0.756 0.244 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.756 0.244 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.754 0.246 0.000
I25 Chronic ischaemic heart disease
0.753 0.247 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.752 0.248 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.752 0.248 0.000
I44.0 Atrioventricular block, first degree
0.750 0.250 0.000
F33 Recurrent depressive disorder
0.750 0.250 0.000
K65-K67 Diseases of peritoneum
0.750 0.250 0.000
K13 Other diseases of lip and oral mucosa
0.749 0.251 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.744 0.256 0.000
V10-V19 Pedal cyclist injured in transport accident
0.743 0.257 0.000
C54 Malignant neoplasm of corpus uteri
0.742 0.257 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.742 0.258 0.000
J40 Bronchitis, not specified as acute or chronic
0.742 0.258 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.741 0.259 0.000
M23.4 Loose body in knee
0.740 0.260 0.000
S70-S79 Injuries to the hip and thigh
0.740 0.260 0.000
K07 Dentofacial anomalies [including malocclusion]
0.739 0.261 0.000
O63 Long labour
0.739 0.261 0.000
Z34 Supervision of normal pregnancy
0.739 0.261 0.000
H40-H42 Glaucoma
0.738 0.262 0.000
M80-M85 Disorders of bone density and structure
0.738 0.262 0.000
F60-F69 Disorders of adult personality and behaviour
0.738 0.262 0.000
M65-M68 Disorders of synovium and tendon
0.737 0.263 0.000
Chapter XXII Codes for special purposes
0.737 0.263 0.000
M47 Spondylosis
0.737 0.263 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.737 0.263 0.000
I31 Other diseases of pericardium
0.736 0.264 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.736 0.264 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.734 0.266 0.000
O02 Other abnormal products of conception
0.733 0.267 0.000
M23.3 Other meniscus derangements
0.733 0.267 0.000
Chapter I Certain infectious and parasitic diseases
0.731 0.269 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.730 0.270 0.000
Z97 Presence of other devices
0.730 0.270 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.730 0.270 0.000
O47 False labour
0.730 0.270 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.729 0.271 0.000
M35 Other systemic involvement of connective tissue
0.728 0.272 0.000
H53-H54 Visual disturbances and blindness
0.728 0.272 0.000
I51.8 Other ill-defined heart diseases
0.728 0.272 0.000
K02.9 Dental caries, unspecified
0.728 0.272 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.727 0.273 0.000
H55-H59 Other disorders of eye and adnexa
0.727 0.273 0.000
S90-S99 Injuries to the ankle and foot
0.727 0.273 0.000
D32.0 Cerebral meninges
0.726 0.273 0.000
M24 Other specific joint derangements
0.726 0.274 0.000
D11 Benign neoplasm of major salivary glands
0.726 0.274 0.000
O66 Other obstructed labour
0.725 0.275 0.000
H43-H45 Disorders of vitreous body and globe
0.724 0.276 0.000
M40-M43 Deforming dorsopathies
0.723 0.276 0.000
I60 Subarachnoid haemorrhage
0.720 0.280 0.000
I38 Endocarditis, valve unspecified
0.719 0.281 0.000
I42 Cardiomyopathy
0.719 0.281 0.000
M19 Other arthrosis
0.718 0.281 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
J18 Pneumonia, organism unspecified
0.717 0.283 0.000
D24 Benign neoplasm of breast
0.716 0.284 0.000
O70.0 First degree perineal laceration during delivery
0.716 0.284 0.000
Z63 Other problems related to primary support group, including family circumstances
0.715 0.285 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.715 0.285 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.715 0.285 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.715 0.285 0.000
Z60.2 Living alone
0.715 0.285 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.714 0.285 0.000
O85-O92 Complications predominantly related to the puerperium
0.714 0.286 0.000
D23 Other benign neoplasms of skin
0.714 0.286 0.000
O42 Premature rupture of membranes
0.714 0.286 0.000
X60-X84 Intentional self-harm
0.713 0.287 0.000
S20-S29 Injuries to the thorax
0.713 0.287 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.712 0.287 0.000
T68 Hypothermia
0.711 0.289 0.000
T39.0 Salicylates
0.711 0.289 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
Z91.5 Personal history of self-harm
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
K51.9 Ulcerative colitis, unspecified
0.710 0.290 0.000
Z89 Acquired absence of limb
0.709 0.291 0.000
Z84 Family history of other conditions
0.709 0.291 0.000
Z81 Family history of mental and behavioural disorders
0.709 0.291 0.000
H50 Other strabismus
0.708 0.292 0.000
D34 Benign neoplasm of thyroid gland
0.707 0.292 0.000
I35.0 Aortic (valve) stenosis
0.707 0.293 0.000
Z95.4 Presence of other heart-valve replacement
0.707 0.293 0.000
H52 Disorders of refraction and accommodation
0.706 0.294 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.705 0.294 0.000
D37.5 Rectum
0.705 0.295 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
J46 Status asthmaticus
0.705 0.295 0.000
H10-H13 Disorders of conjunctiva
0.704 0.296 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.704 0.296 0.000
D46 Myelodysplastic syndromes
0.702 0.297 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.702 0.297 0.000
Z39 Postpartum care and examination
0.702 0.298 0.000
J45 Asthma
0.701 0.299 0.000
D31 Benign neoplasm of eye and adnexa
0.701 0.299 0.000
D30 Benign neoplasm of urinary organs
0.701 0.299 0.000
D29 Benign neoplasm of male genital organs
0.701 0.299 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.701 0.299 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.701 0.299 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.701 0.299 0.000
D19 Benign neoplasm of mesothelial tissue
0.701 0.299 0.000
D16 Benign neoplasm of bone and articular cartilage
0.701 0.299 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.701 0.299 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.701 0.299 0.000
D10 Benign neoplasm of mouth and pharynx
0.701 0.299 0.000
K11 Diseases of salivary glands
0.701 0.299 0.000
Z87.8 Personal history of other specified conditions
0.701 0.299 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.700 0.300 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.699 0.301 0.000
L30 Other dermatitis
0.699 0.301 0.000
Z92.9 Personal history of medical treatment, unspecified
0.699 0.301 0.000
Z92.8 Personal history of other medical treatment
0.699 0.301 0.000
Z92.5 Personal history of rehabilitation measures
0.699 0.301 0.000
Z92.0 Personal history of contraception
0.699 0.301 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.698 0.302 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.696 0.304 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.694 0.306 0.000
O04 Medical abortion
0.694 0.306 0.000
D32.9 Meninges, unspecified
0.694 0.306 0.000
D37.0 Lip, oral cavity and pharynx
0.693 0.307 0.000
Z98 Other postsurgical states
0.692 0.308 0.000
Z37.2 Twins, both liveborn
0.692 0.308 0.000
E70-E90 Metabolic disorders
0.691 0.309 0.000
Y40 Systemic antibiotics
0.691 0.309 0.000
M86-M90 Other osteopathies
0.690 0.309 0.000
O00 Ectopic pregnancy
0.690 0.309 0.000
O30 Multiple gestation
0.690 0.310 0.000
Z33 Pregnant state, incidental
0.690 0.310 0.000
F31 Bipolar affective disorder
0.690 0.310 0.000
O72.1 Other immediate postpartum haemorrhage
0.690 0.310 0.000
Chapter VIII Diseases of the ear and mastoid process
0.690 0.310 0.000
I82 Other venous embolism and thrombosis
0.689 0.311 0.000
I45.8 Other specified conduction disorders
0.688 0.312 0.000
I45.6 Preexcitation syndrome
0.688 0.312 0.000
I45.4 Nonspecific intraventricular block
0.688 0.312 0.000
I45.3 Trifascicular block
0.688 0.312 0.000
I45.2 Bifascicular block
0.688 0.312 0.000
I45.0 Right fascicular block
0.688 0.312 0.000
C80 Malignant neoplasm without specification of site
0.688 0.312 0.000
D25 Leiomyoma of uterus
0.686 0.314 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.686 0.314 0.000
M34 Systemic sclerosis
0.686 0.314 0.000
M33 Dermatopolymyositis
0.686 0.314 0.000
M32 Systemic lupus erythematosus
0.686 0.314 0.000
M30 Polyarteritis nodosa and related conditions
0.686 0.314 0.000
M22 Disorders of patella
0.686 0.314 0.000
M21 Other acquired deformities of limbs
0.686 0.314 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.685 0.314 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.685 0.315 0.000
S40-S49 Injuries to the shoulder and upper arm
0.685 0.315 0.000
C53 Malignant neoplasm of cervix uteri
0.685 0.315 0.000
C51 Malignant neoplasm of vulva
0.685 0.315 0.000
C58 Malignant neoplasm of placenta
0.685 0.315 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.685 0.315 0.000
C52 Malignant neoplasm of vagina
0.685 0.315 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.684 0.316 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.684 0.316 0.000
T39.4 Antirheumatics, not elsewhere classified
0.684 0.316 0.000
T39.2 Pyrazolone derivatives
0.684 0.316 0.000
M25.77 Osteophyte (Ankle and foot)
0.684 0.316 0.000
I44.1 Atrioventricular block, second degree
0.684 0.316 0.000
O36.8 Maternal care for other specified foetal problems
0.683 0.316 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.683 0.317 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.683 0.317 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.683 0.317 0.000
J20-J22 Other acute lower respiratory infections
0.683 0.317 0.000
Y59 Other and unspecified vaccines and biological substances
0.683 0.317 0.000
Y58 Bacterial vaccines
0.683 0.317 0.000
Y57 Other and unspecified drugs and medicaments
0.683 0.317 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.683 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.683 0.317 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.683 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.683 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.683 0.317 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.683 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.683 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.683 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.683 0.317 0.000
Y44 Agents primarily affecting blood constituents
0.683 0.317 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.683 0.317 0.000
M25.9 Joint disorder, unspecified
0.682 0.318 0.000
K10 Other diseases of jaws
0.681 0.319 0.000
K09 Cysts of oral region, not elsewhere classified
0.681 0.319 0.000
K03 Other diseases of hard tissues of teeth
0.681 0.319 0.000
K00 Disorders of tooth development and eruption
0.681 0.319 0.000
F99-F99 Unspecified mental disorder
0.681 0.319 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.681 0.319 0.000
F80-F89 Disorders of psychological development
0.681 0.319 0.000
F70-F79 Mental retardation
0.681 0.319 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.681 0.319 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.681 0.319 0.000
I21 Acute myocardial infarction
0.681 0.319 0.000
J00-J06 Acute upper respiratory infections
0.681 0.319 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.680 0.320 0.000
O74 Complications of anaesthesia during labour and delivery
0.680 0.320 0.000
O73 Retained placenta and membranes, without haemorrhage
0.680 0.320 0.000
O71 Other obstetric trauma
0.680 0.320 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.680 0.320 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.680 0.320 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.680 0.320 0.000
O62 Abnormalities of forces of labour
0.680 0.320 0.000
O61 Failed induction of labour
0.680 0.320 0.000
O60 Preterm delivery
0.680 0.320 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.680 0.320 0.000
K05.3 Chronic periodontitis
0.680 0.320 0.000
D60-D64 Aplastic and other anaemias
0.680 0.320 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.679 0.321 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.679 0.321 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.679 0.321 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.679 0.321 0.000
D45 Polycythaemia vera
0.678 0.322 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.678 0.322 0.000
Y95 Nosocomial condition
0.678 0.322 0.000
J42 Unspecified chronic bronchitis
0.677 0.322 0.000
D18 Haemangioma and lymphangioma, any site
0.677 0.323 0.000
T43.9 Psychotropic drug, unspecified
0.676 0.324 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.676 0.324 0.000
T43.6 Psychostimulants with abuse potential
0.676 0.324 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.676 0.324 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.676 0.324 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.676 0.324 0.000
I86 Varicose veins of other sites
0.676 0.324 0.000
M16.0 Primary coxarthrosis, bilateral
0.676 0.324 0.000
Z38 Liveborn infants according to place of birth
0.675 0.325 0.000
Z36 Antenatal screening
0.675 0.325 0.000
Z32 Pregnancy examination and test
0.675 0.325 0.000
Z31 Procreative management
0.675 0.325 0.000
M48 Other spondylopathies
0.674 0.326 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.673 0.327 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.673 0.327 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.672 0.327 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.672 0.327 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.672 0.327 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.672 0.327 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.672 0.327 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.672 0.327 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.672 0.328 0.000
W00-W19 Falls
0.671 0.329 0.000
O03.9 Complete or unspecified, without complication
0.671 0.329 0.000
Z35.5 Supervision of elderly primigravida
0.670 0.330 0.000
K12 Stomatitis and related lesions
0.669 0.331 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.669 0.331 0.000
K90-K93 Other diseases of the digestive system
0.668 0.332 0.000
O45 Premature separation of placenta [abruptio placentae]
0.668 0.332 0.000
O44 Placenta praevia
0.668 0.332 0.000
O43 Placental disorders
0.668 0.332 0.000
O41 Other disorders of amniotic fluid and membranes
0.668 0.332 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.668 0.332 0.000
O33 Maternal care for known or suspected disproportion
0.668 0.332 0.000
O31 Complications specific to multiple gestation
0.668 0.332 0.000
O40 Polyhydramnios
0.668 0.332 0.000
Z91.6 Personal history of other physical trauma
0.668 0.332 0.000
C57.0 Fallopian tube
0.667 0.333 0.000
J41 Simple and mucopurulent chronic bronchitis
0.667 0.333 0.000
M31 Other necrotising vasculopathies
0.666 0.334 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.665 0.334 0.000
Z93 Artificial opening status
0.663 0.336 0.000
Z94.8 Other transplanted organ and tissue status
0.663 0.336 0.000
C78.7 Secondary malignant neoplasm of liver
0.663 0.337 0.000
F42 Obsessive-compulsive disorder
0.663 0.337 0.000
I51.9 Heart disease, unspecified
0.662 0.337 0.000
I49.9 Cardiac arrhythmia, unspecified
0.662 0.338 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.662 0.338 0.000
F43 Reaction to severe stress, and adjustment disorders
0.662 0.338 0.000
I51.6 Cardiovascular disease, unspecified
0.661 0.339 0.000
I51.5 Myocardial degeneration
0.661 0.339 0.000
I51.4 Myocarditis, unspecified
0.661 0.339 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.661 0.339 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.661 0.339 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.661 0.339 0.000
I51.0 Cardiac septal defect, acquired
0.661 0.339 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.660 0.340 0.000
K01.0 Embedded teeth
0.660 0.340 0.000
L81 Other disorders of pigmentation
0.659 0.341 0.000
M23.9 Internal derangement of knee, unspecified
0.659 0.341 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.659 0.341 0.000
M23.5 Chronic instability of knee
0.659 0.341 0.000
M23.1 Discoid meniscus (congenital)
0.659 0.341 0.000
M23.0 Cystic meniscus
0.659 0.341 0.000
J90-J94 Other diseases of pleura
0.659 0.341 0.000
Z87.0 Personal history of diseases of the respiratory system
0.658 0.342 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.657 0.342 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.657 0.342 0.000
I34.0 Mitral (valve) insufficiency
0.657 0.343 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.655 0.345 0.000
O07 Failed attempted abortion
0.655 0.345 0.000
O06 Unspecified abortion
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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