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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16889916
log Bayes Factor = 20.7757
Chromosome 6   position 24,989,384  (GRCh37) Explore rs16889916 on Ensembl!
Variant rs16889916 is part of Cluster X0174

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
I25.1 Atherosclerotic heart disease
0.995 0.005 0.000
M70-M79 Other soft tissue disorders
0.994 0.006 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
Chapter II Neoplasms
0.992 0.008 0.000
I21 Acute myocardial infarction
0.989 0.011 0.000
M05-M14 Inflammatory polyarthropathies
0.987 0.013 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.984 0.016 0.000
Chapter X Diseases of the respiratory system
0.984 0.016 0.000
M20-M25 Other joint disorders
0.983 0.017 0.000
I21.9 Acute myocardial infarction, unspecified
0.979 0.021 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.977 0.023 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.976 0.024 0.000
C15-C26 Malignant neoplasms of digestive organs
0.974 0.026 0.000
M13 Other arthritis
0.973 0.027 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.970 0.030 0.000
Z92 Personal history of medical treatment
0.966 0.034 0.000
I25.2 Old myocardial infarction
0.966 0.034 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.965 0.035 0.000
I20 Angina pectoris
0.964 0.036 0.000
M13.9 Arthritis, unspecified
0.963 0.037 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.963 0.037 0.000
I10-I15 Hypertensive diseases
0.963 0.037 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.958 0.042 0.000
M75 Shoulder lesions
0.956 0.044 0.000
Chapter XIV Diseases of the genitourinary system
0.956 0.044 0.000
M25 Other joint disorders, not elsewhere classified
0.955 0.045 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.952 0.048 0.000
E10-E14 Diabetes mellitus
0.950 0.050 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.946 0.054 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.941 0.059 0.000
Chapter V Mental and behavioural disorders
0.941 0.059 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.938 0.062 0.000
C18 Malignant neoplasm of colon
0.938 0.062 0.000
C51-C58 Malignant neoplasms of female genital organs
0.935 0.065 0.000
M25.5 Pain in joint
0.931 0.069 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.928 0.072 0.000
N17-N19 Renal failure
0.926 0.074 0.000
E11 Non-insulin-dependent diabetes mellitus
0.925 0.075 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.923 0.077 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.922 0.078 0.000
I30-I52 Other forms of heart disease
0.921 0.079 0.000
J40-J47 Chronic lower respiratory diseases
0.918 0.082 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.915 0.085 0.000
Z95.1 Presence of aortocoronary bypass graft
0.915 0.085 0.000
N86 Erosion and ectropion of cervix uteri
0.912 0.088 0.000
I12 Hypertensive renal disease
0.910 0.090 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.909 0.091 0.000
M79.8 Other specified soft tissue disorders
0.908 0.092 0.000
J45 Asthma
0.907 0.093 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.906 0.094 0.000
M75.4 Impingement syndrome of shoulder
0.903 0.097 0.000
N18 Chronic renal failure
0.903 0.097 0.000
M25.56 Pain in joint (Lower leg)
0.903 0.097 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.900 0.100 0.000
E11.9 Without complications
0.899 0.101 0.000
J45.9 Asthma, unspecified
0.899 0.101 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.897 0.103 0.000
I20.9 Angina pectoris, unspecified
0.895 0.105 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.893 0.107 0.000
J95-J99 Other diseases of the respiratory system
0.892 0.108 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.884 0.116 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.884 0.116 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.883 0.117 0.000
T90 Sequelae of injuries of head
0.881 0.119 0.000
O60-O75 Complications of labour and delivery
0.880 0.120 0.000
O16 Unspecified maternal hypertension
0.879 0.121 0.000
C56 Malignant neoplasm of ovary
0.874 0.126 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.868 0.132 0.000
S20-S29 Injuries to the thorax
0.868 0.132 0.000
T66-T78 Other and unspecified effects of external causes
0.867 0.133 0.000
S80-S89 Injuries to the knee and lower leg
0.867 0.133 0.000
Z95.4 Presence of other heart-valve replacement
0.865 0.135 0.000
Chapter I Certain infectious and parasitic diseases
0.863 0.137 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.863 0.137 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.861 0.139 0.000
I12.0 Hypertensive renal disease with renal failure
0.859 0.141 0.000
J90-J94 Other diseases of pleura
0.859 0.141 0.000
E20-E35 Disorders of other endocrine glands
0.857 0.143 0.000
I24 Other acute ischaemic heart diseases
0.856 0.144 0.000
N18.3 Chronic kidney disease, stage 3
0.853 0.147 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.852 0.148 0.000
C18.9 Colon, unspecified
0.850 0.150 0.000
T93 Sequelae of injuries of lower limb
0.843 0.157 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.838 0.162 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.837 0.163 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.836 0.164 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.836 0.164 0.000
Z02 Examination and encounter for administrative purposes
0.836 0.164 0.000
I05-I09 Chronic rheumatic heart diseases
0.832 0.168 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.830 0.170 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.826 0.174 0.000
J98 Other respiratory disorders
0.825 0.175 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.824 0.176 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.822 0.178 0.000
M22 Disorders of patella
0.821 0.179 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.819 0.181 0.000
M10 Gout
0.812 0.188 0.000
M75.1 Rotator cuff syndrome
0.812 0.188 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.811 0.189 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.810 0.190 0.000
Z86 Personal history of certain other diseases
0.810 0.190 0.000
S00-S09 Injuries to the head
0.809 0.191 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.807 0.193 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.806 0.194 0.000
S40-S49 Injuries to the shoulder and upper arm
0.805 0.195 0.000
N85.2 Hypertrophy of uterus
0.805 0.195 0.000
I51 Complications and ill-defined descriptions of heart disease
0.802 0.198 0.000
I10 Essential (primary) hypertension
0.800 0.200 0.000
S50-S59 Injuries to the elbow and forearm
0.797 0.203 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.795 0.205 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.792 0.208 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.791 0.209 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.209 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.790 0.210 0.000
J98.1 Pulmonary collapse
0.787 0.213 0.000
M86-M90 Other osteopathies
0.787 0.213 0.000
M25.4 Effusion of joint
0.786 0.214 0.000
N92 Excessive, frequent and irregular menstruation
0.786 0.214 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.786 0.214 0.000
Z95.0 Presence of cardiac pacemaker
0.786 0.214 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.785 0.215 0.000
I20.8 Other forms of angina pectoris
0.784 0.216 0.000
N18.5 Chronic kidney disease, stage 5
0.783 0.217 0.000
C25 Malignant neoplasm of pancreas
0.782 0.218 0.000
Z37 Outcome of delivery
0.781 0.219 0.000
I20.0 Unstable angina
0.780 0.220 0.000
M23 Internal derangement of knee
0.780 0.220 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.780 0.220 0.000
J09-J18 Influenza and pneumonia
0.780 0.220 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.780 0.220 0.000
C20 Malignant neoplasm of rectum
0.779 0.221 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.779 0.221 0.000
Z94 Transplanted organ and tissue status
0.777 0.223 0.000
Z04 Examination and observation for other reasons
0.777 0.223 0.000
J90 Pleural effusion, not elsewhere classified
0.776 0.224 0.000
I22 Subsequent myocardial infarction
0.775 0.225 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.775 0.225 0.000
T78 Adverse effects, not elsewhere classified
0.774 0.226 0.000
Z73 Problems related to life-management difficulty
0.774 0.226 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.772 0.227 0.000
Z30 Contraceptive management
0.770 0.230 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.770 0.230 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.769 0.231 0.000
M31 Other necrotising vasculopathies
0.768 0.232 0.000
M11 Other crystal arthropathies
0.767 0.233 0.000
C18.6 Descending colon
0.766 0.234 0.000
M25.57 Pain in joint (Ankle and foot)
0.766 0.234 0.000
F80-F89 Disorders of psychological development
0.765 0.235 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.763 0.237 0.000
L20-L30 Dermatitis and eczema
0.763 0.237 0.000
I50 Heart failure
0.762 0.238 0.000
M72 Fibroblastic disorders
0.762 0.238 0.000
C18.2 Ascending colon
0.762 0.238 0.000
C54 Malignant neoplasm of corpus uteri
0.761 0.239 0.000
E14 Unspecified diabetes mellitus
0.761 0.239 0.000
O72 Postpartum haemorrhage
0.761 0.239 0.000
N85.0 Endometrial glandular hyperplasia
0.759 0.241 0.000
N80 Endometriosis
0.758 0.242 0.000
Z95.3 Presence of xenogenic heart valve
0.758 0.242 0.000
E28 Ovarian dysfunction
0.757 0.242 0.000
Chapter VII Diseases of the eye and adnexa
0.757 0.243 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.757 0.243 0.000
E11.5 With peripheral circulatory complications
0.755 0.244 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.755 0.245 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.754 0.246 0.000
O36 Maternal care for other known or suspected foetal problems
0.753 0.246 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.753 0.247 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.753 0.247 0.000
F30-F39 Mood [affective] disorders
0.753 0.247 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.751 0.249 0.000
M77 Other enthesopathies
0.751 0.249 0.000
M75.2 Bicipital tendinitis
0.750 0.250 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.749 0.251 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.748 0.252 0.000
E11.3 With ophthalmic complications
0.748 0.252 0.000
M07 Psoriatic and enteropathic arthropathies
0.748 0.252 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.747 0.253 0.000
M24 Other specific joint derangements
0.745 0.255 0.000
Z02.8 Other examinations for administrative purposes
0.744 0.256 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.743 0.257 0.000
A30-A49 Other bacterial diseases
0.742 0.258 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.741 0.259 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.741 0.259 0.000
O34.1 Maternal care for tumour of corpus uteri
0.739 0.261 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.738 0.262 0.000
E10 Insulin-dependent diabetes mellitus
0.737 0.263 0.000
I11 Hypertensive heart disease
0.736 0.264 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.736 0.264 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.736 0.264 0.000
N18.4 Chronic kidney disease, stage 4
0.735 0.265 0.000
M75.5 Bursitis of shoulder
0.735 0.265 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.734 0.266 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.733 0.267 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.732 0.268 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.732 0.268 0.000
S70-S79 Injuries to the hip and thigh
0.730 0.270 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.730 0.270 0.000
I20.1 Angina pectoris with documented spasm
0.728 0.272 0.000
Z88.2 Personal history of allergy to sulphonamides
0.727 0.273 0.000
Z72 Problems related to lifestyle
0.726 0.274 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.725 0.275 0.000
N85.4 Malposition of uterus
0.724 0.276 0.000
I21.4 Acute subendocardial myocardial infarction
0.724 0.276 0.000
M05 Seropositive rheumatoid arthritis
0.723 0.277 0.000
I42 Cardiomyopathy
0.722 0.278 0.000
Z85 Personal history of malignant neoplasm
0.722 0.278 0.000
Z86.0 Personal history of other neoplasms
0.721 0.279 0.000
M35 Other systemic involvement of connective tissue
0.721 0.279 0.000
O70 Perineal laceration during delivery
0.720 0.280 0.000
T92 Sequelae of injuries of upper limb
0.719 0.281 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.717 0.283 0.000
C18.0 Caecum
0.717 0.283 0.000
N87 Dysplasia of cervix uteri
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
I12.9 Hypertensive renal disease without renal failure
0.715 0.285 0.000
S81 Open wound of lower leg
0.714 0.286 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.714 0.286 0.000
O85-O92 Complications predominantly related to the puerperium
0.714 0.286 0.000
J60-J70 Lung diseases due to external agents
0.714 0.286 0.000
Z97 Presence of other devices
0.713 0.287 0.000
M76 Enthesopathies of lower limb, excluding foot
0.712 0.288 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.712 0.288 0.000
M71 Other bursopathies
0.712 0.288 0.000
J46 Status asthmaticus
0.712 0.288 0.000
Z89 Acquired absence of limb
0.712 0.288 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
Z81 Family history of mental and behavioural disorders
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.710 0.290 0.000
M79.7 Fibromyalgia
0.710 0.290 0.000
C18.4 Transverse colon
0.710 0.290 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.709 0.291 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.709 0.291 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.709 0.291 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.708 0.292 0.000
C60-C63 Malignant neoplasms of male genital organs
0.708 0.292 0.000
M14 Arthropathies in other diseases classified elsewhere
0.708 0.292 0.000
M12 Other specific arthropathies
0.708 0.292 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.708 0.292 0.000
M08 Juvenile arthritis
0.708 0.292 0.000
M25.54 Pain in joint (Hand)
0.708 0.292 0.000
Z60 Problems related to social environment
0.707 0.293 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.705 0.295 0.000
M34 Systemic sclerosis
0.705 0.295 0.000
M33 Dermatopolymyositis
0.705 0.295 0.000
M32 Systemic lupus erythematosus
0.705 0.295 0.000
M30 Polyarteritis nodosa and related conditions
0.705 0.295 0.000
M21 Other acquired deformities of limbs
0.705 0.295 0.000
M25.50 Pain in joint (Multiple sites)
0.704 0.296 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.704 0.296 0.000
Z31 Procreative management
0.703 0.296 0.000
B95-B98 Bacterial, viral and other infectious agents
0.702 0.298 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.701 0.298 0.000
Z36 Antenatal screening
0.701 0.298 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.701 0.299 0.000
I24.8 Other forms of acute ischaemic heart disease
0.700 0.300 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.700 0.300 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.700 0.300 0.000
I35 Nonrheumatic aortic valve disorders
0.700 0.300 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.698 0.302 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.698 0.302 0.000
C21 Malignant neoplasm of anus and anal canal
0.698 0.302 0.000
C17 Malignant neoplasm of small intestine
0.698 0.302 0.000
C23 Malignant neoplasm of gallbladder
0.698 0.302 0.000
M13.8 Other specified arthritis
0.698 0.302 0.000
M13.1 Monoarthritis, not elsewhere classified
0.698 0.302 0.000
M13.0 Polyarthritis, unspecified
0.698 0.302 0.000
N97 Female infertility
0.697 0.303 0.000
S90-S99 Injuries to the ankle and foot
0.696 0.303 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.696 0.304 0.000
Z37.0 Single live birth
0.696 0.304 0.000
E40-E46 Malnutrition
0.695 0.305 0.000
N19 Unspecified renal failure
0.695 0.305 0.000
E50-E64 Other nutritional deficiencies
0.694 0.306 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.694 0.306 0.000
I49 Other cardiac arrhythmias
0.693 0.307 0.000
Z92.9 Personal history of medical treatment, unspecified
0.693 0.307 0.000
Z92.8 Personal history of other medical treatment
0.693 0.307 0.000
Z92.5 Personal history of rehabilitation measures
0.693 0.307 0.000
Z92.0 Personal history of contraception
0.693 0.307 0.000
Z10 Routine general health check-up of defined subpopulation
0.692 0.308 0.000
M65-M68 Disorders of synovium and tendon
0.692 0.308 0.000
J30-J39 Other diseases of upper respiratory tract
0.691 0.309 0.000
M13.98 Arthritis, unspecified (Other)
0.691 0.309 0.000
M13.93 Arthritis, unspecified (Forearm)
0.691 0.309 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.691 0.309 0.000
O42 Premature rupture of membranes
0.691 0.309 0.000
I15 Secondary hypertension
0.690 0.310 0.000
I13 Hypertensive heart and renal disease
0.690 0.310 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.690 0.310 0.000
I44 Atrioventricular and left bundle-branch block
0.689 0.311 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.689 0.311 0.000
N99-N99 Other disorders of the genitourinary system
0.687 0.313 0.000
I38 Endocarditis, valve unspecified
0.687 0.313 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.687 0.313 0.000
I08 Multiple valve diseases
0.687 0.313 0.000
T98 Sequelae of other and unspecified effects of external causes
0.686 0.313 0.000
T95 Sequelae of burns, corrosions and frostbite
0.686 0.313 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.686 0.313 0.000
T91 Sequelae of injuries of neck and trunk
0.686 0.313 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.686 0.313 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.686 0.313 0.000
M10.9 Gout, unspecified
0.687 0.313 0.000
E28.2 Polycystic ovarian syndrome
0.686 0.314 0.000
M75.8 Other shoulder lesions
0.686 0.314 0.000
M75.9 Shoulder lesion, unspecified
0.686 0.314 0.000
M25.9 Joint disorder, unspecified
0.685 0.315 0.000
M25.8 Other specified joint disorders
0.685 0.315 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.685 0.315 0.000
M25.3 Other instability of joint
0.685 0.315 0.000
M25.2 Flail joint
0.685 0.315 0.000
M25.1 Fistula of joint
0.685 0.315 0.000
M25.0 Haemarthrosis
0.685 0.315 0.000
S27 Injury of other and unspecified intrathoracic organs
0.684 0.316 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.684 0.316 0.000
Z86.7 Personal history of diseases of the circulatory system
0.683 0.317 0.000
O15 Eclampsia
0.683 0.317 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.683 0.317 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.683 0.317 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.683 0.317 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.683 0.317 0.000
I31 Other diseases of pericardium
0.682 0.317 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.682 0.318 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.682 0.318 0.000
E13 Other specified diabetes mellitus
0.681 0.319 0.000
E12 Malnutrition-related diabetes mellitus
0.681 0.319 0.000
C18.7 Sigmoid colon
0.681 0.319 0.000
J45.0 Predominantly allergic asthma
0.681 0.319 0.000
N20-N23 Urolithiasis
0.679 0.320 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.679 0.321 0.000
T93.2 Sequelae of other fractures of lower limb
0.679 0.321 0.000
I50.1 Left ventricular failure
0.679 0.321 0.000
O63 Long labour
0.677 0.323 0.000
O80-O84 Delivery
0.676 0.324 0.000
M79.9 Soft tissue disorder, unspecified
0.675 0.325 0.000
M79.5 Residual foreign body in soft tissue
0.675 0.325 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.675 0.325 0.000
M79.3 Panniculitis, unspecified
0.675 0.325 0.000
M79.2 Neuralgia and neuritis, unspecified
0.675 0.325 0.000
M79.1 Myalgia
0.675 0.325 0.000
O72.1 Other immediate postpartum haemorrhage
0.675 0.325 0.000
F99-F99 Unspecified mental disorder
0.674 0.325 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.674 0.325 0.000
F70-F79 Mental retardation
0.674 0.325 0.000
F60-F69 Disorders of adult personality and behaviour
0.674 0.325 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.674 0.325 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.674 0.325 0.000
Z99.1 Dependence on respirator
0.674 0.326 0.000
E27 Other disorders of adrenal gland
0.674 0.326 0.000
Z74 Problems related to care-provider dependency
0.674 0.326 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.673 0.327 0.000
Z71.8 Other specified counselling
0.673 0.327 0.000
N98 Complications associated with artificial fertilisation
0.673 0.327 0.000
N91 Absent, scanty and rare menstruation
0.673 0.327 0.000
N82 Fistulae involving female genital tract
0.673 0.327 0.000
N96 Habitual aborter
0.673 0.327 0.000
C18.8 Overlapping lesion of colon
0.672 0.328 0.000
C18.5 Splenic flexure
0.672 0.328 0.000
C18.3 Hepatic flexure
0.672 0.328 0.000
C18.1 Appendix
0.672 0.328 0.000
N60-N64 Disorders of breast
0.672 0.328 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.672 0.328 0.000
C53 Malignant neoplasm of cervix uteri
0.671 0.329 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.670 0.329 0.000
C51 Malignant neoplasm of vulva
0.670 0.329 0.000
C58 Malignant neoplasm of placenta
0.670 0.329 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.670 0.329 0.000
C52 Malignant neoplasm of vagina
0.670 0.329 0.000
M22.4 Chondromalacia patellae
0.670 0.330 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.670 0.330 0.000
S20 Superficial injury of thorax
0.670 0.330 0.000
Z99.2 Dependence on renal dialysis
0.669 0.331 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.668 0.331 0.000
E65-E68 Obesity and other hyperalimentation
0.668 0.332 0.000
M25.59 Pain in joint (Site unspecified)
0.668 0.332 0.000
M25.58 Pain in joint (Other)
0.668 0.332 0.000
M25.52 Pain in joint (Upper arm)
0.668 0.332 0.000
N18.2 Chronic kidney disease, stage 2
0.668 0.332 0.000
Chapter VI Diseases of the nervous system
0.667 0.333 0.000
Chapter XX External causes of morbidity and mortality
0.667 0.333 0.000
N72 Inflammatory disease of cervix uteri
0.667 0.333 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.666 0.333 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.666 0.334 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.665 0.335 0.000
I51.8 Other ill-defined heart diseases
0.665 0.335 0.000
I33 Acute and subacute endocarditis
0.665 0.335 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.665 0.335 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.665 0.335 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.665 0.335 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.665 0.335 0.000
Z82.2 Family history of deafness and hearing loss
0.665 0.335 0.000
Z82.1 Family history of blindness and visual loss
0.665 0.335 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.665 0.335 0.000
M25.46 Effusion of joint (Lower leg)
0.665 0.335 0.000
N17 Acute renal failure
0.664 0.336 0.000
E16 Other disorders of pancreatic internal secretion
0.664 0.336 0.000
E11.8 With unspecified complications
0.663 0.336 0.000
E11.7 With multiple complications
0.663 0.336 0.000
E11.6 With other specified complications
0.663 0.336 0.000
E11.2 With renal complications
0.663 0.336 0.000
E11.1 With ketoacidosis
0.663 0.336 0.000
E11.0 With coma
0.663 0.336 0.000
N94.1 Dyspareunia
0.662 0.338 0.000
Z76 Persons encountering health services in other circumstances
0.662 0.338 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.662 0.338 0.000
O45 Premature separation of placenta [abruptio placentae]
0.661 0.339 0.000
O44 Placenta praevia
0.661 0.339 0.000
O43 Placental disorders
0.661 0.339 0.000
O41 Other disorders of amniotic fluid and membranes
0.661 0.339 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.661 0.339 0.000
O33 Maternal care for known or suspected disproportion
0.661 0.339 0.000
O31 Complications specific to multiple gestation
0.661 0.339 0.000
O40 Polyhydramnios
0.661 0.339 0.000
I52 Other heart disorders in diseases classified elsewhere
0.660 0.340 0.000
I48 Atrial fibrillation and flutter
0.660 0.340 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.660 0.340 0.000
I41 Myocarditis in diseases classified elsewhere
0.660 0.340 0.000
I40 Acute myocarditis
0.660 0.340 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.660 0.340 0.000
I37 Pulmonary valve disorders
0.660 0.340 0.000
I36 Nonrheumatic tricuspid valve disorders
0.660 0.340 0.000
I32 Pericarditis in diseases classified elsewhere
0.660 0.340 0.000
I30 Acute pericarditis
0.660 0.340 0.000
O70.0 First degree perineal laceration during delivery
0.660 0.340 0.000
I34 Nonrheumatic mitral valve disorders
0.659 0.340 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.659 0.340 0.000
N70 Salpingitis and oophoritis
0.659 0.341 0.000
O36.6 Maternal care for excessive foetal growth
0.659 0.341 0.000
Z75 Problems related to medical facilities and other health care
0.659 0.341 0.000
J41 Simple and mucopurulent chronic bronchitis
0.658 0.341 0.000
M45-M49 Spondylopathies
0.659 0.341 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.658 0.342 0.000
Chapter VIII Diseases of the ear and mastoid process
0.658 0.342 0.000
Z35 Supervision of high-risk pregnancy
0.658 0.342 0.000
M79.6 Pain in limb
0.657 0.343 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.657 0.343 0.000
D60-D64 Aplastic and other anaemias
0.657 0.343 0.000
Z04.9 Examination and observation for unspecified reason
0.657 0.343 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.656 0.344 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.656 0.344 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.656 0.344 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.656 0.344 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.656 0.344 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.656 0.344 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.656 0.344 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.656 0.344 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.656 0.344 0.000
T36 Poisoning by systemic antibiotics
0.656 0.344 0.000
Z96 Presence of other functional implants
0.656 0.344 0.000
C79 Secondary malignant neoplasm of other sites
0.655 0.345 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.654 0.346 0.000
M40-M43 Deforming dorsopathies
0.654 0.346 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.654 0.346 0.000
S52 Fracture of forearm
0.653 0.347 0.000
M25.53 Pain in joint (Forearm)
0.652 0.348 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.652 0.348 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.652 0.348 0.000
Z09.4 Follow-up examination after treatment of fracture
0.652 0.348 0.000
Z09.3 Follow-up examination after psychotherapy
0.652 0.348 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.652 0.348 0.000
C64-C68 Malignant neoplasms of urinary tract
0.652 0.348 0.000
M80-M85 Disorders of bone density and structure
0.651 0.348 0.000
Z73.3 Stress, not elsewhere classified
0.651 0.349 0.000
O30 Multiple gestation
0.651 0.349 0.000
M79.88 Other specified soft tissue disorders (Other)
0.651 0.349 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.651 0.349 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.651 0.349 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.651 0.349 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.651 0.349 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.651 0.349 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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