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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs76246633
log Bayes Factor = 27.2748
Chromosome 16   position 74,924,716  (GRCh37) Explore rs76246633 on Ensembl!
Variant rs76246633 is part of Cluster X0174

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Z00-Z13 Persons encountering health services for examination and investigation
1.000 0.000 0.000
Z92 Personal history of medical treatment
0.999 0.001 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.999 0.001 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.997 0.003 0.000
I10-I15 Hypertensive diseases
0.997 0.003 0.000
I10 Essential (primary) hypertension
0.995 0.005 0.000
Chapter VIII Diseases of the ear and mastoid process
0.995 0.005 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.992 0.008 0.000
H65-H75 Diseases of middle ear and mastoid
0.992 0.008 0.000
C50-C50 Malignant neoplasm of breast
0.989 0.011 0.000
D10-D36 Benign neoplasms
0.989 0.011 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.988 0.012 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.988 0.012 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.985 0.015 0.000
C64-C68 Malignant neoplasms of urinary tract
0.984 0.016 0.000
M75 Shoulder lesions
0.984 0.016 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.983 0.017 0.000
C50 Malignant neoplasm of breast
0.982 0.018 0.000
C67 Malignant neoplasm of bladder
0.979 0.021 0.000
H40-H42 Glaucoma
0.977 0.023 0.000
Z80 Family history of malignant neoplasm
0.976 0.024 0.000
H30-H36 Disorders of choroid and retina
0.975 0.025 0.000
Z45 Adjustment and management of implanted device
0.973 0.027 0.000
C67.9 Bladder, unspecified
0.971 0.029 0.000
M20-M25 Other joint disorders
0.968 0.032 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.967 0.033 0.000
M75.4 Impingement syndrome of shoulder
0.964 0.036 0.000
Z45.2 Adjustment and management of vascular access device
0.963 0.037 0.000
H40 Glaucoma
0.962 0.038 0.000
Z46 Fitting and adjustment of other devices
0.961 0.039 0.000
C60-C63 Malignant neoplasms of male genital organs
0.958 0.042 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.957 0.043 0.000
Z95.2 Presence of prosthetic heart valve
0.957 0.043 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.955 0.045 0.000
D12.0 Caecum
0.950 0.050 0.000
C50.4 Upper-outer quadrant of breast
0.950 0.050 0.000
I25.2 Old myocardial infarction
0.949 0.051 0.000
D00-D09 In situ neoplasms
0.946 0.054 0.000
Chapter XX External causes of morbidity and mortality
0.939 0.061 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.939 0.061 0.000
H72 Perforation of tympanic membrane
0.938 0.062 0.000
H71 Cholesteatoma of middle ear
0.936 0.064 0.000
D12.3 Transverse colon
0.935 0.065 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.935 0.065 0.000
M23 Internal derangement of knee
0.934 0.066 0.000
Z13 Special screening examination for other diseases and disorders
0.931 0.069 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.930 0.070 0.000
Z46.6 Fitting and adjustment of urinary device
0.926 0.074 0.000
Z95.4 Presence of other heart-valve replacement
0.925 0.075 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.925 0.075 0.000
C61 Malignant neoplasm of prostate
0.924 0.076 0.000
H36 Retinal disorders in diseases classified elsewhere
0.923 0.077 0.000
C50.9 Breast, unspecified
0.921 0.079 0.000
C15-C26 Malignant neoplasms of digestive organs
0.914 0.086 0.000
M15-M19 Arthrosis
0.911 0.089 0.000
Z85 Personal history of malignant neoplasm
0.905 0.095 0.000
H74 Other disorders of middle ear and mastoid
0.904 0.096 0.000
H40.9 Glaucoma, unspecified
0.904 0.096 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.898 0.102 0.000
D12.4 Descending colon
0.896 0.104 0.000
Chapter V Mental and behavioural disorders
0.896 0.104 0.000
D12.5 Sigmoid colon
0.895 0.105 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.894 0.106 0.000
I24 Other acute ischaemic heart diseases
0.893 0.107 0.000
Z51 Other medical care
0.892 0.108 0.000
M24 Other specific joint derangements
0.892 0.108 0.000
E10-E14 Diabetes mellitus
0.892 0.108 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.888 0.112 0.000
H36.0 Diabetic retinopathy
0.886 0.114 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.884 0.116 0.000
Z94 Transplanted organ and tissue status
0.882 0.118 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.882 0.118 0.000
M05-M14 Inflammatory polyarthropathies
0.880 0.120 0.000
H66 Suppurative and unspecified otitis media
0.879 0.121 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.877 0.123 0.000
Z92.3 Personal history of irradiation
0.874 0.126 0.000
H40.2 Primary angle-closure glaucoma
0.874 0.126 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.874 0.126 0.000
H25-H28 Disorders of lens
0.866 0.134 0.000
F30-F39 Mood [affective] disorders
0.865 0.135 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.863 0.137 0.000
Z51.1 Chemotherapy session for neoplasm
0.860 0.140 0.000
I25.1 Atherosclerotic heart disease
0.857 0.143 0.000
C18 Malignant neoplasm of colon
0.856 0.144 0.000
I25.5 Ischaemic cardiomyopathy
0.856 0.144 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.855 0.145 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.854 0.146 0.000
E14 Unspecified diabetes mellitus
0.853 0.147 0.000
M79.6 Pain in limb
0.850 0.150 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.849 0.151 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.848 0.152 0.000
M19 Other arthrosis
0.848 0.152 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.847 0.153 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.845 0.155 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.845 0.155 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.840 0.160 0.000
Z95.1 Presence of aortocoronary bypass graft
0.839 0.161 0.000
Z92.8 Personal history of other medical treatment
0.839 0.161 0.000
M45-M49 Spondylopathies
0.837 0.163 0.000
C67.4 Posterior wall of bladder
0.836 0.164 0.000
H33 Retinal detachments and breaks
0.834 0.166 0.000
M40-M43 Deforming dorsopathies
0.832 0.168 0.000
H40.0 Glaucoma suspect
0.830 0.170 0.000
F32 Depressive episode
0.828 0.172 0.000
I21 Acute myocardial infarction
0.828 0.172 0.000
Z88.5 Personal history of allergy to narcotic agent
0.828 0.172 0.000
M71 Other bursopathies
0.827 0.173 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.824 0.176 0.000
M75.0 Adhesive capsulitis of shoulder
0.822 0.178 0.000
Z98 Other postsurgical states
0.821 0.179 0.000
M18 Arthrosis of first carpometacarpal joint
0.821 0.179 0.000
M24.1 Other articular cartilage disorders
0.819 0.181 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.819 0.181 0.000
D12.2 Ascending colon
0.818 0.182 0.000
D05 Carcinoma in situ of breast
0.818 0.182 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.817 0.183 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.815 0.185 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.813 0.187 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.812 0.188 0.000
Z45.1 Adjustment and management of infusion pump
0.812 0.188 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.811 0.189 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.810 0.190 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.810 0.190 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.807 0.193 0.000
D36 Benign neoplasm of other and unspecified sites
0.804 0.196 0.000
E14.3 With ophthalmic complications
0.803 0.197 0.000
W00-W19 Falls
0.803 0.197 0.000
H26 Other cataract
0.803 0.197 0.000
C50.3 Lower-inner quadrant of breast
0.800 0.200 0.000
H35 Other retinal disorders
0.799 0.201 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.799 0.201 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.798 0.202 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.797 0.203 0.000
Z80.3 Family history of malignant neoplasm of breast
0.796 0.204 0.000
Z12 Special screening examination for neoplasms
0.796 0.204 0.000
I05-I09 Chronic rheumatic heart diseases
0.794 0.206 0.000
M19.9 Arthrosis, unspecified
0.793 0.207 0.000
F32.9 Depressive episode, unspecified
0.792 0.208 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.792 0.208 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.792 0.208 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.790 0.210 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.788 0.212 0.000
I30-I52 Other forms of heart disease
0.788 0.212 0.000
Z95.3 Presence of xenogenic heart valve
0.788 0.212 0.000
I24.8 Other forms of acute ischaemic heart disease
0.786 0.214 0.000
Z89 Acquired absence of limb
0.785 0.215 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.784 0.216 0.000
Z92.0 Personal history of contraception
0.780 0.220 0.000
Z96 Presence of other functional implants
0.780 0.220 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.779 0.221 0.000
E70-E90 Metabolic disorders
0.778 0.222 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.778 0.222 0.000
M19.94 Arthrosis, unspecified (Hand)
0.778 0.222 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.777 0.223 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.777 0.223 0.000
C50.5 Lower-outer quadrant of breast
0.777 0.223 0.000
W20-W49 Exposure to inanimate mechanical forces
0.775 0.225 0.000
D09 Carcinoma in situ of other and unspecified sites
0.775 0.225 0.000
H66.3 Other chronic suppurative otitis media
0.775 0.225 0.000
E10 Insulin-dependent diabetes mellitus
0.774 0.226 0.000
H74.4 Polyp of middle ear
0.774 0.226 0.000
I95 Hypotension
0.774 0.226 0.000
Z54 Convalescence
0.773 0.227 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.772 0.228 0.000
C71 Malignant neoplasm of brain
0.771 0.229 0.000
M35 Other systemic involvement of connective tissue
0.771 0.229 0.000
I71 Aortic aneurysm and dissection
0.771 0.229 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.768 0.232 0.000
D10 Benign neoplasm of mouth and pharynx
0.767 0.233 0.000
M79.66 Pain in limb (Lower leg)
0.767 0.233 0.000
S80-S89 Injuries to the knee and lower leg
0.767 0.233 0.000
Z88.2 Personal history of allergy to sulphonamides
0.765 0.235 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.765 0.235 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.762 0.237 0.000
M25 Other joint disorders, not elsewhere classified
0.762 0.238 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.761 0.239 0.000
M79.0 Rheumatism, unspecified
0.760 0.240 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.759 0.241 0.000
D27 Benign neoplasm of ovary
0.757 0.243 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.756 0.244 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.754 0.246 0.000
M75.3 Calcific tendinitis of shoulder
0.753 0.247 0.000
H55-H59 Other disorders of eye and adnexa
0.752 0.247 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.752 0.248 0.000
M23.4 Loose body in knee
0.751 0.249 0.000
Z49 Care involving dialysis
0.750 0.250 0.000
M23.3 Other meniscus derangements
0.746 0.254 0.000
M80-M85 Disorders of bone density and structure
0.744 0.256 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.744 0.256 0.000
M65-M68 Disorders of synovium and tendon
0.744 0.256 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.743 0.257 0.000
M75.1 Rotator cuff syndrome
0.743 0.257 0.000
Z97 Presence of other devices
0.742 0.258 0.000
H10-H13 Disorders of conjunctiva
0.742 0.258 0.000
D26 Other benign neoplasms of uterus
0.741 0.258 0.000
C69 Malignant neoplasm of eye and adnexa
0.739 0.261 0.000
H74.0 Tympanosclerosis
0.739 0.261 0.000
M00-M03 Infectious arthropathies
0.739 0.261 0.000
C50.0 Nipple and areola
0.738 0.262 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.738 0.262 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.738 0.262 0.000
M86-M90 Other osteopathies
0.737 0.263 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.737 0.263 0.000
Chapter XXII Codes for special purposes
0.735 0.265 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.735 0.265 0.000
M77 Other enthesopathies
0.734 0.265 0.000
Z42 Follow-up care involving plastic surgery
0.734 0.266 0.000
M79.8 Other specified soft tissue disorders
0.733 0.267 0.000
M41 Scoliosis
0.733 0.267 0.000
H72.0 Central perforation of tympanic membrane
0.730 0.270 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.729 0.271 0.000
V40-V49 Car occupant injured in transport accident
0.729 0.271 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.728 0.272 0.000
H40.5 Glaucoma secondary to other eye disorders
0.728 0.272 0.000
M06 Other rheumatoid arthritis
0.727 0.273 0.000
V10-V19 Pedal cyclist injured in transport accident
0.726 0.274 0.000
H60-H62 Diseases of external ear
0.724 0.276 0.000
C62 Malignant neoplasm of testis
0.724 0.276 0.000
H90-H95 Other disorders of ear
0.724 0.276 0.000
H26.9 Cataract, unspecified
0.723 0.277 0.000
I86 Varicose veins of other sites
0.723 0.277 0.000
D03 Melanoma in situ
0.722 0.277 0.000
D18 Haemangioma and lymphangioma, any site
0.722 0.277 0.000
Z40 Prophylactic surgery
0.722 0.278 0.000
E50-E64 Other nutritional deficiencies
0.722 0.278 0.000
S82 Fracture of lower leg, including ankle
0.721 0.279 0.000
C67.2 Lateral wall of bladder
0.719 0.281 0.000
I05 Rheumatic mitral valve diseases
0.719 0.281 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.718 0.282 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
Z10 Routine general health check-up of defined subpopulation
0.717 0.283 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.717 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.716 0.283 0.000
Z92.5 Personal history of rehabilitation measures
0.716 0.283 0.000
M48 Other spondylopathies
0.717 0.283 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.717 0.283 0.000
Z94.0 Kidney transplant status
0.716 0.284 0.000
Z94.4 Liver transplant status
0.716 0.284 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.716 0.284 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.715 0.285 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.715 0.285 0.000
I15 Secondary hypertension
0.715 0.285 0.000
I13 Hypertensive heart and renal disease
0.715 0.285 0.000
I11 Hypertensive heart disease
0.715 0.285 0.000
E14.9 Without complications
0.714 0.286 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.713 0.287 0.000
Z83 Family history of other specific disorders
0.713 0.287 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.713 0.287 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.712 0.288 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.712 0.288 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.711 0.289 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.711 0.289 0.000
H70 Mastoiditis and related conditions
0.711 0.289 0.000
H69 Other disorders of Eustachian tube
0.711 0.289 0.000
H68 Eustachian salpingitis and obstruction
0.711 0.289 0.000
H67 Otitis media in diseases classified elsewhere
0.711 0.289 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.710 0.290 0.000
C18.7 Sigmoid colon
0.710 0.290 0.000
H73 Other disorders of tympanic membrane
0.710 0.290 0.000
C18.9 Colon, unspecified
0.709 0.291 0.000
D31 Benign neoplasm of eye and adnexa
0.709 0.291 0.000
D30 Benign neoplasm of urinary organs
0.709 0.291 0.000
D29 Benign neoplasm of male genital organs
0.709 0.291 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.709 0.291 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.709 0.291 0.000
D19 Benign neoplasm of mesothelial tissue
0.709 0.291 0.000
D16 Benign neoplasm of bone and articular cartilage
0.709 0.291 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.709 0.291 0.000
C91 Lymphoid leukaemia
0.709 0.291 0.000
M23.8 Other internal derangements of knee
0.709 0.291 0.000
D12.9 Anus and anal canal
0.708 0.291 0.000
D12.1 Appendix
0.708 0.291 0.000
Z44 Fitting and adjustment of external prosthetic device
0.708 0.292 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.706 0.294 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.706 0.294 0.000
C66 Malignant neoplasm of ureter
0.706 0.294 0.000
C65 Malignant neoplasm of renal pelvis
0.706 0.294 0.000
M75.8 Other shoulder lesions
0.706 0.294 0.000
M75.9 Shoulder lesion, unspecified
0.706 0.294 0.000
M75.2 Bicipital tendinitis
0.706 0.294 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.706 0.294 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.705 0.295 0.000
D25 Leiomyoma of uterus
0.705 0.295 0.000
Y43 Primarily systemic agents
0.705 0.295 0.000
E10.3 With ophthalmic complications
0.704 0.295 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.704 0.296 0.000
Z52 Donors of organs and tissues
0.704 0.296 0.000
C50.6 Axillary tail of breast
0.704 0.296 0.000
H34 Retinal vascular occlusions
0.704 0.296 0.000
C50.1 Central portion of breast
0.703 0.297 0.000
M79.7 Fibromyalgia
0.703 0.297 0.000
F31 Bipolar affective disorder
0.703 0.297 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.703 0.297 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.702 0.298 0.000
I12 Hypertensive renal disease
0.702 0.298 0.000
C67.8 Overlapping lesion of bladder
0.702 0.298 0.000
C67.7 Urachus
0.702 0.298 0.000
C67.6 Ureteric orifice
0.702 0.298 0.000
C67.5 Bladder neck
0.702 0.298 0.000
C67.3 Anterior wall of bladder
0.702 0.298 0.000
C67.1 Dome of bladder
0.702 0.298 0.000
C67.0 Trigone of bladder
0.702 0.298 0.000
C18.0 Caecum
0.701 0.298 0.000
C25 Malignant neoplasm of pancreas
0.701 0.299 0.000
H42 Glaucoma in diseases classified elsewhere
0.700 0.299 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.700 0.300 0.000
Z80.6 Family history of leukaemia
0.700 0.300 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.700 0.300 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.699 0.301 0.000
H31 Other disorders of choroid
0.699 0.301 0.000
H30 Chorioretinal inflammation
0.699 0.301 0.000
M79.60 Pain in limb (Multiple sites)
0.698 0.302 0.000
M13 Other arthritis
0.698 0.302 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.698 0.302 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.697 0.302 0.000
Z45.3 Adjustment and management of implanted hearing device
0.697 0.302 0.000
D05.1 Intraductal carcinoma in situ
0.697 0.303 0.000
F99-F99 Unspecified mental disorder
0.697 0.303 0.000
M11 Other crystal arthropathies
0.696 0.304 0.000
I99 Other and unspecified disorders of circulatory system
0.696 0.304 0.000
I70 Atherosclerosis
0.695 0.305 0.000
Z96.1 Presence of intraocular lens
0.695 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M34 Systemic sclerosis
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M32 Systemic lupus erythematosus
0.694 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.306 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.694 0.306 0.000
S40-S49 Injuries to the shoulder and upper arm
0.693 0.307 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.693 0.307 0.000
Z94.8 Other transplanted organ and tissue status
0.692 0.308 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.692 0.308 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.691 0.309 0.000
D04 Carcinoma in situ of skin
0.690 0.309 0.000
Q00-Q07 Congenital malformations of the nervous system
0.690 0.310 0.000
H40.8 Other glaucoma
0.690 0.310 0.000
H40.6 Glaucoma secondary to drugs
0.690 0.310 0.000
H40.4 Glaucoma secondary to eye inflammation
0.690 0.310 0.000
H40.3 Glaucoma secondary to eye trauma
0.690 0.310 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.689 0.311 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.689 0.311 0.000
Z46.8 Fitting and adjustment of other specified devices
0.689 0.311 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.689 0.311 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.689 0.311 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.689 0.311 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.689 0.311 0.000
Z46.1 Fitting and adjustment of hearing aid
0.689 0.311 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.689 0.311 0.000
S82.8 Fractures of other parts of lower leg
0.689 0.311 0.000
Z51.5 Palliative care
0.689 0.311 0.000
E13 Other specified diabetes mellitus
0.688 0.312 0.000
H26.8 Other specified cataract
0.688 0.312 0.000
Q50-Q56 Congenital malformations of genital organs
0.688 0.312 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.688 0.312 0.000
H66.9 Otitis media, unspecified
0.687 0.313 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.687 0.313 0.000
C60 Malignant neoplasm of penis
0.687 0.313 0.000
M25.7 Osteophyte
0.687 0.313 0.000
D34 Benign neoplasm of thyroid gland
0.687 0.313 0.000
C90.0 Multiple myeloma
0.686 0.314 0.000
Y57 Other and unspecified drugs and medicaments
0.686 0.314 0.000
M46 Other inflammatory spondylopathies
0.686 0.314 0.000
I50 Heart failure
0.686 0.314 0.000
H33.4 Traction detachment of retina
0.684 0.316 0.000
M07 Psoriatic and enteropathic arthropathies
0.683 0.317 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.683 0.317 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.683 0.317 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.682 0.318 0.000
H27 Other disorders of lens
0.681 0.318 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.681 0.319 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.680 0.320 0.000
Z95.0 Presence of cardiac pacemaker
0.679 0.321 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.679 0.321 0.000
Z51.3 Blood transfusion without reported diagnosis
0.679 0.321 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.679 0.321 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.678 0.322 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.678 0.322 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.678 0.322 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.678 0.322 0.000
Z98.0 Intestinal bypass and anastomosis status
0.677 0.323 0.000
V20-V29 Motorcycle rider injured in transport accident
0.676 0.324 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.673 0.326 0.000
Y35-Y36 Legal intervention and operations of war
0.673 0.326 0.000
Y10-Y34 Event of undetermined intent
0.673 0.326 0.000
Y00-Y09 Assault
0.673 0.326 0.000
X85-X99 Assault
0.673 0.326 0.000
X60-X84 Intentional self-harm
0.673 0.326 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.673 0.326 0.000
X50-X57 Overexertion, travel and privation
0.673 0.326 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.673 0.326 0.000
X30-X39 Exposure to forces of nature
0.673 0.326 0.000
X20-X29 Contact with venomous animals and plants
0.673 0.326 0.000
X10-X19 Contact with heat and hot substances
0.673 0.326 0.000
X00-X09 Exposure to smoke, fire and flames
0.673 0.326 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.673 0.326 0.000
W75-W84 Other accidental threats to breathing
0.673 0.326 0.000
W65-W74 Accidental drowning and submersion
0.673 0.326 0.000
W50-W64 Exposure to animate mechanical forces
0.673 0.326 0.000
V98-V99 Other and unspecified transport accidents
0.673 0.326 0.000
V95-V97 Air and space transport accidents
0.673 0.326 0.000
V90-V94 Water transport accidents
0.673 0.326 0.000
V80-V89 Other land transport accidents
0.673 0.326 0.000
V70-V79 Bus occupant injured in transport accident
0.673 0.326 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.673 0.326 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.673 0.326 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.673 0.326 0.000
V01-V09 Pedestrian injured in transport accident
0.673 0.326 0.000
M79.9 Soft tissue disorder, unspecified
0.673 0.326 0.000
M79.5 Residual foreign body in soft tissue
0.673 0.326 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.673 0.326 0.000
M79.3 Panniculitis, unspecified
0.673 0.326 0.000
M79.2 Neuralgia and neuritis, unspecified
0.673 0.326 0.000
M79.1 Myalgia
0.673 0.326 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.673 0.326 0.000
H52 Disorders of refraction and accommodation
0.673 0.327 0.000
H72.8 Other perforations of tympanic membrane
0.672 0.328 0.000
H72.2 Other marginal perforations of tympanic membrane
0.672 0.328 0.000
H72.1 Attic perforation of tympanic membrane
0.672 0.328 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.671 0.329 0.000
M21 Other acquired deformities of limbs
0.671 0.329 0.000
C18.2 Ascending colon
0.670 0.330 0.000
D07.5 Prostate
0.669 0.331 0.000
M23.9 Internal derangement of knee, unspecified
0.669 0.331 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.669 0.331 0.000
M23.5 Chronic instability of knee
0.669 0.331 0.000
M23.1 Discoid meniscus (congenital)
0.669 0.331 0.000
M23.0 Cystic meniscus
0.669 0.331 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.668 0.332 0.000
F60-F69 Disorders of adult personality and behaviour
0.668 0.332 0.000
Z41 Procedures for purposes other than remedying health state
0.668 0.332 0.000
C20 Malignant neoplasm of rectum
0.668 0.332 0.000
I95.1 Orthostatic hypotension
0.668 0.332 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.667 0.333 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.667 0.333 0.000
Z13.5 Special screening examination for eye and ear disorders
0.667 0.333 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.667 0.333 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.667 0.333 0.000
Z13.2 Special screening examination for nutritional disorders
0.667 0.333 0.000
Z13.1 Special screening examination for diabetes mellitus
0.667 0.333 0.000
E40-E46 Malnutrition
0.667 0.333 0.000
M75.5 Bursitis of shoulder
0.666 0.334 0.000
D11 Benign neoplasm of major salivary glands
0.663 0.336 0.000
Z13.9 Special screening examination, unspecified
0.663 0.337 0.000
S70-S79 Injuries to the hip and thigh
0.662 0.338 0.000
E20-E35 Disorders of other endocrine glands
0.662 0.338 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.662 0.338 0.000
S90-S99 Injuries to the ankle and foot
0.661 0.339 0.000
M31 Other necrotising vasculopathies
0.660 0.339 0.000
Z85.6 Personal history of leukaemia
0.660 0.339 0.000
D06 Carcinoma in situ of cervix uteri
0.660 0.340 0.000
M72 Fibroblastic disorders
0.659 0.341 0.000
M19.0 Primary arthrosis of other joints
0.656 0.344 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.656 0.344 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.656 0.344 0.000
C21 Malignant neoplasm of anus and anal canal
0.656 0.344 0.000
C17 Malignant neoplasm of small intestine
0.656 0.344 0.000
C16 Malignant neoplasm of stomach
0.656 0.344 0.000
C23 Malignant neoplasm of gallbladder
0.656 0.344 0.000
D32 Benign neoplasm of meninges
0.655 0.345 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.654 0.346 0.000
I46 Cardiac arrest
0.654 0.346 0.000
I81 Portal vein thrombosis
0.653 0.347 0.000
M15 Polyarthrosis
0.653 0.347 0.000
D12.7 Rectosigmoid junction
0.653 0.347 0.000
H33.5 Other retinal detachments
0.652 0.348 0.000
D09.0 Bladder
0.652 0.348 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.652 0.348 0.000
I95.9 Hypotension, unspecified
0.652 0.348 0.000
I31 Other diseases of pericardium
0.652 0.348 0.000
Z63 Other problems related to primary support group, including family circumstances
0.651 0.349 0.000
M22 Disorders of patella
0.651 0.349 0.000
Z90.1 Acquired absence of breast(s)
0.650 0.350 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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