TreeWAS – Variant ID: rs10790383

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	0.997	0.003	0.000
I20.0 Unstable angina	0.995	0.005	0.000
I22 Subsequent myocardial infarction	0.986	0.014	0.000
I25.2 Old myocardial infarction	0.975	0.025	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.952	0.048	0.000
I25.5 Ischaemic cardiomyopathy	0.931	0.069	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.920	0.080	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.895	0.105	0.000
I23 Certain current complications following acute myocardial infarction	0.857	0.143	0.000
I21 Acute myocardial infarction	0.841	0.159	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.837	0.163	0.000
I21.4 Acute subendocardial myocardial infarction	0.825	0.175	0.000
I25.3 Aneurysm of heart	0.770	0.230	0.000
I20.8 Other forms of angina pectoris	0.764	0.236	0.000
I23.8 Other current complications following acute myocardial infarction	0.755	0.245	0.000
I25.6 Silent myocardial ischaemia	0.736	0.264	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.688	0.312	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.686	0.314	0.000
I22.8 Subsequent myocardial infarction of other sites	0.648	0.352	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.615	0.385	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.615	0.385	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.615	0.385	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.615	0.385	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.615	0.385	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.615	0.385	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.615	0.385	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.603	0.397	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.565	0.434	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.562	0.438	0.000
I25.4 Coronary artery aneurysm	0.535	0.465	0.000
I21.9 Acute myocardial infarction, unspecified	0.485	0.515	0.000
I24 Other acute ischaemic heart diseases	0.448	0.552	0.000
H40.9 Glaucoma, unspecified	0.363	0.637	0.000
H40 Glaucoma	0.352	0.648	0.000
I20.1 Angina pectoris with documented spasm	0.352	0.648	0.000
I24.1 Dressler's syndrome	0.348	0.652	0.000
H40.0 Glaucoma suspect	0.342	0.658	0.000
H40.2 Primary angle-closure glaucoma	0.330	0.670	0.000
I24.8 Other forms of acute ischaemic heart disease	0.314	0.686	0.000
H40.1 Primary open-angle glaucoma	0.297	0.703	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.266	0.734	0.000
H40.8 Other glaucoma	0.260	0.740	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.259	0.741	0.000
H40.6 Glaucoma secondary to drugs	0.253	0.747	0.000
H40.4 Glaucoma secondary to eye inflammation	0.243	0.757	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.229	0.771	0.000
H40.3 Glaucoma secondary to eye trauma	0.205	0.794	0.000
H40.5 Glaucoma secondary to other eye disorders	0.170	0.830	0.000
H40-H42 Glaucoma	0.147	0.853	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.119	0.881	0.000
H42 Glaucoma in diseases classified elsewhere	0.106	0.894	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.076	0.924	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.076	0.924	0.000
C67.9 Bladder, unspecified	0.071	0.929	0.000
C67 Malignant neoplasm of bladder	0.064	0.936	0.000
C67.1 Dome of bladder	0.061	0.939	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.940	0.060
E27 Other disorders of adrenal gland	0.000	0.941	0.059
C67.3 Anterior wall of bladder	0.058	0.942	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.943	0.057
C67.0 Trigone of bladder	0.055	0.945	0.000
C67.5 Bladder neck	0.053	0.947	0.000
E27.2 Addisonian crisis	0.000	0.949	0.051
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.953	0.047
C67.7 Urachus	0.046	0.954	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.954	0.046
C67.4 Posterior wall of bladder	0.045	0.955	0.000
C67.2 Lateral wall of bladder	0.044	0.955	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.957	0.042
E27.0 Other adrenocortical overactivity	0.000	0.957	0.042
E27.8 Other specified disorders of adrenal gland	0.000	0.960	0.040
C67.8 Overlapping lesion of bladder	0.034	0.966	0.000
C67.6 Ureteric orifice	0.033	0.967	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.969	0.031
E20 Hypoparathyroidism	0.000	0.973	0.027
E29 Testicular dysfunction	0.000	0.974	0.026
E23 Hypofunction and other disorders of pituitary gland	0.000	0.974	0.026
E20.9 Hypoparathyroidism, unspecified	0.000	0.975	0.025
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.025	0.975	0.000
E26 Hyperaldosteronism	0.000	0.976	0.024
E24 Cushing's syndrome	0.000	0.976	0.024
E29.1 Testicular hypofunction	0.000	0.977	0.023
E34 Other endocrine disorders	0.000	0.978	0.022
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.978	0.022
E32 Diseases of thymus	0.000	0.978	0.022
E31 Polyglandular dysfunction	0.000	0.978	0.022
E30 Disorders of puberty, not elsewhere classified	0.000	0.978	0.022
E23.0 Hypopituitarism	0.000	0.978	0.022
I08.0 Disorders of both mitral and aortic valves	0.022	0.978	0.000
E25 Adrenogenital disorders	0.000	0.979	0.021
E23.7 Disorder of pituitary gland, unspecified	0.000	0.980	0.020
E23.6 Other disorders of pituitary gland	0.000	0.980	0.020
E20.1 Pseudohypoparathyroidism	0.000	0.980	0.019
E20.0 Idiopathic hypoparathyroidism	0.000	0.980	0.019
E26.0 Primary hyperaldosteronism	0.000	0.980	0.019
E24.0 Pituitary-dependent Cushing's disease	0.000	0.981	0.019
I08.8 Other multiple valve diseases	0.019	0.981	0.000
E29.9 Testicular dysfunction, unspecified	0.000	0.981	0.019
E29.8 Other testicular dysfunction	0.000	0.981	0.019
E29.0 Testicular hyperfunction	0.000	0.981	0.019
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.981	0.019
E23.1 Drug-induced hypopituitarism	0.000	0.981	0.019
E24.2 Drug-induced Cushing's syndrome	0.000	0.981	0.019
I08 Multiple valve diseases	0.019	0.981	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.982	0.017
E20.8 Other hypoparathyroidism	0.000	0.982	0.017
E26.8 Other hyperaldosteronism	0.000	0.982	0.017
E26.1 Secondary hyperaldosteronism	0.000	0.982	0.017
E24.8 Other Cushing's syndrome	0.000	0.982	0.017
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.982	0.017
E24.3 Ectopic ACTH syndrome	0.000	0.982	0.017
E24.1 Nelson's syndrome	0.000	0.982	0.017
E34.9 Endocrine disorder, unspecified	0.000	0.983	0.017
E23.2 Diabetes insipidus	0.000	0.983	0.017
E22 Hyperfunction of pituitary gland	0.000	0.983	0.017
E34.5 Androgen resistance syndrome	0.000	0.984	0.016
E34.4 Constitutional tall stature	0.000	0.984	0.016
E34.3 Short stature, not elsewhere classified	0.000	0.984	0.016
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.984	0.016
E34.1 Other hypersecretion of intestinal hormones	0.000	0.984	0.016
E24.9 Cushing's syndrome, unspecified	0.000	0.984	0.016
E30.9 Disorder of puberty, unspecified	0.000	0.984	0.016
E30.8 Other disorders of puberty	0.000	0.984	0.016
E30.1 Precocious puberty	0.000	0.984	0.016
E30.0 Delayed puberty	0.000	0.984	0.016
E31.9 Polyglandular dysfunction, unspecified	0.000	0.984	0.016
E31.8 Other polyglandular dysfunction	0.000	0.984	0.016
E31.1 Polyglandular hyperfunction	0.000	0.984	0.016
E31.0 Autoimmune polyglandular failure	0.000	0.984	0.016
E32.9 Disease of thymus, unspecified	0.000	0.984	0.016
E32.8 Other diseases of thymus	0.000	0.984	0.016
E32.1 Abscess of thymus	0.000	0.984	0.016
E32.0 Persistent hyperplasia of thymus	0.000	0.984	0.016
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.984	0.016
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.984	0.016
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.984	0.016
E34.8 Other specified endocrine disorders	0.000	0.984	0.016
I05-I09 Chronic rheumatic heart diseases	0.016	0.984	0.000
E34.0 Carcinoid syndrome	0.000	0.985	0.015
E28 Ovarian dysfunction	0.000	0.985	0.015
E25.9 Adrenogenital disorder, unspecified	0.000	0.985	0.015
E25.8 Other adrenogenital disorders	0.000	0.985	0.015
Chapter IX Diseases of the circulatory system	0.015	0.985	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.015	0.985	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.986	0.014
I08.9 Multiple valve disease, unspecified	0.014	0.986	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.014	0.986	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.987	0.013
I99 Other and unspecified disorders of circulatory system	0.013	0.987	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.013	0.987	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.987	0.012
E22.8 Other hyperfunction of pituitary gland	0.000	0.987	0.012
E22.1 Hyperprolactinaemia	0.000	0.988	0.012
I09 Other rheumatic heart diseases	0.012	0.988	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.012	0.988	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.012	0.988	0.000
I05 Rheumatic mitral valve diseases	0.011	0.989	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.989	0.011
E28.8 Other ovarian dysfunction	0.000	0.989	0.011
E28.1 Androgen excess	0.000	0.989	0.011
E28.0 Oestrogen excess	0.000	0.989	0.011
I06 Rheumatic aortic valve diseases	0.011	0.989	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.011	0.989	0.000
K26.7 Chronic without haemorrhage or perforation	0.010	0.990	0.000
C64-C68 Malignant neoplasms of urinary tract	0.010	0.990	0.000
I05.0 Mitral stenosis	0.010	0.990	0.000
N89.5 Stricture and atresia of vagina	0.000	0.990	0.010
I09.9 Rheumatic heart disease, unspecified	0.010	0.990	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.990	0.010
I00-I02 Acute rheumatic fever	0.010	0.990	0.000
I05.1 Rheumatic mitral insufficiency	0.010	0.990	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.009	0.991	0.000
I07 Rheumatic tricuspid valve diseases	0.009	0.991	0.000
I09.8 Other specified rheumatic heart diseases	0.009	0.991	0.000
I09.2 Chronic rheumatic pericarditis	0.009	0.991	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.009	0.991	0.000
I09.0 Rheumatic myocarditis	0.009	0.991	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.009	0.991	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.009	0.991	0.000
I98.0 Cardiovascular syphilis	0.009	0.991	0.000
E28.3 Primary ovarian failure	0.000	0.991	0.009
R04.0 Epistaxis	0.009	0.991	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.009	0.991	0.000
R17 Unspecified jaundice	0.009	0.991	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.009	0.991	0.000
I05.8 Other mitral valve diseases	0.008	0.992	0.000
I06.8 Other rheumatic aortic valve diseases	0.008	0.992	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.008	0.992	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.008	0.992	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.992	0.008
I97.0 Postcardiotomy syndrome	0.008	0.992	0.000
I06.0 Rheumatic aortic stenosis	0.008	0.992	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.992	0.008
I95 Hypotension	0.008	0.992	0.000
R04 Haemorrhage from respiratory passages	0.008	0.992	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.008	0.992	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.008	0.992	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.008	0.992	0.000
Z87.8 Personal history of other specified conditions	0.008	0.992	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.008	0.992	0.000
I06.1 Rheumatic aortic insufficiency	0.007	0.992	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.008	0.992	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.008	0.992	0.000
R04.2 Haemoptysis	0.007	0.993	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.993	0.007
I02 Rheumatic chorea	0.007	0.993	0.000
I01 Rheumatic fever with heart involvement	0.007	0.993	0.000
I95.0 Idiopathic hypotension	0.007	0.993	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
I95.2 Hypotension due to drugs	0.007	0.993	0.000
I05.2 Mitral stenosis with insufficiency	0.007	0.993	0.000
I07.9 Tricuspid valve disease, unspecified	0.007	0.993	0.000
I07.8 Other tricuspid valve diseases	0.007	0.993	0.000
I07.2 Tricuspid stenosis with insufficiency	0.007	0.993	0.000
I07.0 Tricuspid stenosis	0.007	0.993	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.007	0.993	0.000
C68.0 Urethra	0.006	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.993	0.000
B34.9 Viral infection, unspecified	0.007	0.993	0.000
I95.8 Other hypotension	0.006	0.993	0.000
E21.2 Other hyperparathyroidism	0.000	0.994	0.006
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.994	0.006
I97.1 Other functional disturbances following cardiac surgery	0.006	0.994	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.994	0.006
C64 Malignant neoplasm of kidney, except renal pelvis	0.006	0.994	0.000
I00 Rheumatic fever without mention of heart involvement	0.006	0.994	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
C66 Malignant neoplasm of ureter	0.006	0.994	0.000
R04.9 Haemorrhage from respiratory passages, unspecified	0.006	0.994	0.000
R04.1 Haemorrhage from throat	0.006	0.994	0.000
C68.8 Overlapping lesion of urinary organs	0.006	0.994	0.000
C68.1 Paraurethral glands	0.006	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
Z88.2 Personal history of allergy to sulphonamides	0.006	0.994	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.006	0.994	0.000
N80.8 Other endometriosis	0.000	0.994	0.006
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.994	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.005	0.994	0.000
I01.8 Other acute rheumatic heart disease	0.005	0.994	0.000
I01.2 Acute rheumatic myocarditis	0.005	0.994	0.000
I01.1 Acute rheumatic endocarditis	0.005	0.994	0.000
I01.0 Acute rheumatic pericarditis	0.005	0.994	0.000
I02.9 Rheumatic chorea without heart involvement	0.005	0.994	0.000
I02.0 Rheumatic chorea with heart involvement	0.005	0.994	0.000
C68.9 Urinary organ, unspecified	0.005	0.995	0.000
I42.9 Cardiomyopathy, unspecified	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.995	0.005
B34 Viral infection of unspecified site	0.005	0.995	0.000
C65 Malignant neoplasm of renal pelvis	0.004	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
I07.1 Tricuspid insufficiency	0.004	0.995	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.996	0.004
I05.9 Mitral valve disease, unspecified	0.004	0.996	0.000
E21.0 Primary hyperparathyroidism	0.000	0.996	0.004
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.004	0.996	0.000
E03.9 Hypothyroidism, unspecified	0.004	0.996	0.000
B34.4 Papovirus infection, unspecified	0.004	0.996	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.004	0.996	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.004	0.996	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.004	0.996	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.004	0.996	0.000
B34.8 Other viral infections of unspecified site	0.004	0.996	0.000
X23.9 Unspecified place	0.004	0.996	0.000
B34.1 Enterovirus infection, unspecified	0.004	0.996	0.000
B34.3 Parvovirus infection, unspecified	0.004	0.996	0.000
B34.2 Coronavirus infection, unspecified	0.004	0.996	0.000
B34.0 Adenovirus infection, unspecified	0.004	0.996	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.003	0.997	0.000
Z39.1 Care and examination of lactating mother	0.003	0.997	0.000
I33.0 Acute and subacute infective endocarditis	0.003	0.997	0.000
I46.0 Cardiac arrest with successful resuscitation	0.003	0.997	0.000
G93.9 Disorder of brain, unspecified	0.003	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.003	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.003	0.997	0.000
I42.0 Dilated cardiomyopathy	0.003	0.997	0.000
C50.0 Nipple and areola	0.003	0.997	0.000
I42 Cardiomyopathy	0.003	0.997	0.000
I10-I15 Hypertensive diseases	0.003	0.997	0.000
I28 Other diseases of pulmonary vessels	0.003	0.997	0.000
H33.5 Other retinal detachments	0.000	0.997	0.003
E03 Other hypothyroidism	0.003	0.997	0.000
S71.1 Open wound of thigh	0.003	0.997	0.000
I33 Acute and subacute endocarditis	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.003
F81.9 Developmental disorder of scholastic skills, unspecified	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
R09.0 Asphyxia	0.000	0.997	0.003
M89.8 Other specified disorders of bone	0.003	0.997	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.997	0.003
E03.1 Congenital hypothyroidism without goitre	0.003	0.997	0.000
I42.5 Other restrictive cardiomyopathy	0.003	0.997	0.000
L81.9 Disorder of pigmentation, unspecified	0.003	0.997	0.000
I42.6 Alcoholic cardiomyopathy	0.003	0.997	0.000
M89.0 Algoneurodystrophy	0.003	0.997	0.000
M25.88 Other specified joint disorders (Other)	0.003	0.997	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
M25.57 Pain in joint (Ankle and foot)	0.000	0.997	0.003
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.002	0.997	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.997	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.997	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.997	0.000
I44.2 Atrioventricular block, complete	0.003	0.997	0.000
X23 Contact with hornets, wasps and bees	0.002	0.997	0.000
E03.8 Other specified hypothyroidism	0.002	0.998	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.002	0.998	0.000
I44.3 Other and unspecified atrioventricular block	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
I33.9 Acute endocarditis, unspecified	0.002	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
I13 Hypertensive heart and renal disease	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
I42.4 Endocardial fibroelastosis	0.002	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.002	0.998	0.000
I46 Cardiac arrest	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.002	0.998	0.000
M89 Other disorders of bone	0.002	0.998	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.002	0.998	0.000
I28.1 Aneurysm of pulmonary artery	0.002	0.998	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.002	0.998	0.000
I30-I52 Other forms of heart disease	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
H05.0 Acute inflammation of orbit	0.002	0.998	0.000
E03.5 Myxoedema coma	0.002	0.998	0.000
E03.4 Atrophy of thyroid (acquired)	0.002	0.998	0.000
E03.3 Postinfectious hypothyroidism	0.002	0.998	0.000
F34.1 Dysthymia	0.000	0.998	0.002
L50.9 Urticaria, unspecified	0.002	0.998	0.000
M25.8 Other specified joint disorders	0.002	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
M20.0 Deformity of finger(s)	0.000	0.998	0.002
I46.1 Sudden cardiac death, so described	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
K76.6 Portal hypertension	0.002	0.998	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
O63.0 Prolonged first stage (of labour)	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
F30.0 Hypomania	0.000	0.998	0.002
I42.7 Cardiomyopathy due to drugs and other external agents	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.998	0.002
X23.0 Home	0.002	0.998	0.000
I12 Hypertensive renal disease	0.002	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
M25.82 Other specified joint disorders (Upper arm)	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.002	0.998	0.000
I44.4 Left anterior fascicular block	0.002	0.998	0.000
I44 Atrioventricular and left bundle-branch block	0.002	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
X23.8 Other specified place	0.002	0.998	0.000
X23.7 Farm	0.002	0.998	0.000
X23.6 Industrial and construction area	0.002	0.998	0.000
X23.5 Trade and service area	0.002	0.998	0.000
X23.4 Street and highway	0.002	0.998	0.000
X23.3 Sports and athletics area	0.002	0.998	0.000
X23.2 School, other institution and public administrative area	0.002	0.998	0.000
X23.1 Residential institution	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
I26 Pulmonary embolism	0.002	0.998	0.000
I36 Nonrheumatic tricuspid valve disorders	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
M25.83 Other specified joint disorders (Forearm)	0.002	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.002	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.002	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.002	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.002	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.002	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
I47.0 Reentry ventricular arrhythmia	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
I52 Other heart disorders in diseases classified elsewhere	0.002	0.998	0.000
I48 Atrial fibrillation and flutter	0.002	0.998	0.000
I41 Myocarditis in diseases classified elsewhere	0.002	0.998	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.002	0.998	0.000
I32 Pericarditis in diseases classified elsewhere	0.002	0.998	0.000
N89 Other noninflammatory disorders of vagina	0.000	0.998	0.002
L50 Urticaria	0.002	0.998	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
L50.1 Idiopathic urticaria	0.002	0.998	0.000
L50.0 Allergic urticaria	0.002	0.998	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.002	0.998	0.000
I30 Acute pericarditis	0.002	0.998	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.002	0.998	0.000
I95.1 Orthostatic hypotension	0.002	0.998	0.000
I38 Endocarditis, valve unspecified	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
R84.5 Abnormal microbiological findings	0.002	0.998	0.000
I40 Acute myocarditis	0.002	0.998	0.000
T21.3 Burn of third degree of trunk	0.000	0.998	0.002
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.998	0.002
Y83.9 Surgical procedure, unspecified	0.002	0.998	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
T48.5 Anti-common-cold drugs	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.002	0.998	0.000
I44.5 Left posterior fascicular block	0.002	0.998	0.000
Z96.2 Presence of otological and audiological implants	0.002	0.998	0.000
I47 Paroxysmal tachycardia	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.002	0.998	0.000
I42.8 Other cardiomyopathies	0.002	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.002	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.002	0.998	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.002	0.998	0.000
D13.0 Oesophagus	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.998	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.002	0.998	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.002	0.998	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.002	0.998	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.002	0.998	0.000
I15 Secondary hypertension	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.001	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations