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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant cluster associations

Hospitalization Episode Statistics (HES)

Cluster X0143
log Bayes Factor = 179.808
contains 8 variants:
rs115263666
lBF = 19.980
Chr 1 : 195,978,714
rs4632337
lBF = 14.828
Chr 2 : 216,766,065
rs79156452
lBF = 15.661
Chr 3 : 188,651,313
rs115717162
lBF = 14.581
Chr 5 : 40,088,101
rs115352742
lBF = 19.231
Chr 5 : 133,828,896
rs17797221
lBF = 24.143
Chr 8 : 97,995,627
rs34634894
lBF = 20.200
Chr 9 : 82,652,022
rs55812591
lBF = 19.782
Chr10 : 134,021,576
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M25.5 Pain in joint
1.000 0.000 0.000
M25 Other joint disorders, not elsewhere classified
1.000 0.000 0.000
M54 Dorsalgia
1.000 0.000 0.000
M79 Other soft tissue disorders, not elsewhere classified
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
1.000 0.000 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
1.000 0.000 0.000
M54.5 Low back pain
1.000 0.000 0.000
R63 Symptoms and signs concerning food and fluid intake
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
J34 Other disorders of nose and nasal sinuses
1.000 0.000 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
1.000 0.000 0.000
B95-B98 Bacterial, viral and other infectious agents
1.000 0.000 0.000
M15-M19 Arthrosis
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
1.000 0.000 0.000
J31.0 Chronic rhinitis
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
S60-S69 Injuries to the wrist and hand
1.000 0.000 0.000
G50-G59 Nerve, nerve root and plexus disorders
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M23 Internal derangement of knee
1.000 0.000 0.000
M50 Cervical disk disorders
1.000 0.000 0.000
M17 Gonarthrosis [arthrosis of knee]
0.999 0.001 0.000
Z51 Other medical care
0.999 0.001 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.999 0.001 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.999 0.001 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.999 0.001 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.999 0.001 0.000
M17.0 Primary gonarthrosis, bilateral
0.999 0.001 0.000
Z50 Care involving use of rehabilitation procedures
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
R20 Disturbances of skin sensation
0.999 0.001 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.999 0.001 0.000
M47 Spondylosis
0.999 0.001 0.000
Z51.5 Palliative care
0.999 0.001 0.000
M79.0 Rheumatism, unspecified
0.999 0.001 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.999 0.001 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.999 0.001 0.000
M25.51 Pain in joint (Shoulder region)
0.998 0.002 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.998 0.002 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.998 0.002 0.000
M54.2 Cervicalgia
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
R63.4 Abnormal weight loss
0.998 0.002 0.000
M25.7 Osteophyte
0.998 0.002 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.998 0.002 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.998 0.002 0.000
M79.6 Pain in limb
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.997 0.003 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.997 0.003 0.000
K70-K77 Diseases of liver
0.996 0.004 0.000
G90-G99 Other disorders of the nervous system
0.996 0.004 0.000
F30-F39 Mood [affective] disorders
0.996 0.004 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.996 0.004 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.996 0.004 0.000
R53 Malaise and fatigue
0.995 0.005 0.000
M80 Osteoporosis with pathological fracture
0.995 0.005 0.000
J34.3 Hypertrophy of nasal turbinates
0.995 0.005 0.000
M54.56 Low back pain (Lumbar region)
0.995 0.005 0.000
M48 Other spondylopathies
0.995 0.005 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.995 0.005 0.000
J32 Chronic sinusitis
0.995 0.005 0.000
Y43 Primarily systemic agents
0.994 0.006 0.000
I05-I09 Chronic rheumatic heart diseases
0.994 0.006 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.994 0.006 0.000
D69 Purpura and other haemorrhagic conditions
0.994 0.006 0.000
M54.59 Low back pain (Site unspecified)
0.993 0.007 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.992 0.008 0.000
M23.8 Other internal derangements of knee
0.992 0.008 0.000
Z94 Transplanted organ and tissue status
0.991 0.009 0.000
M25.77 Osteophyte (Ankle and foot)
0.991 0.009 0.000
M48.0 Spinal stenosis
0.991 0.009 0.000
O47 False labour
0.991 0.009 0.000
B35-B49 Mycoses
0.991 0.009 0.000
M54.22 Cervicalgia (Cervical region)
0.991 0.009 0.000
K11 Diseases of salivary glands
0.990 0.010 0.000
I25 Chronic ischaemic heart disease
0.990 0.010 0.000
M50.1 Cervical disk disorder with radiculopathy
0.989 0.011 0.000
M47.9 Spondylosis, unspecified
0.989 0.011 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.989 0.011 0.000
M06.9 Rheumatoid arthritis, unspecified
0.989 0.011 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.989 0.011 0.000
G40-G47 Episodic and paroxysmal disorders
0.989 0.011 0.000
T43.2 Other and unspecified antidepressants
0.989 0.011 0.000
I74 Arterial embolism and thrombosis
0.989 0.011 0.000
S62 Fracture at wrist and hand level
0.988 0.012 0.000
D69.6 Thrombocytopenia, unspecified
0.988 0.012 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.988 0.012 0.000
M06.0 Seronegative rheumatoid arthritis
0.987 0.013 0.000
F33 Recurrent depressive disorder
0.987 0.013 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.987 0.013 0.000
M31 Other necrotising vasculopathies
0.987 0.013 0.000
R63.0 Anorexia
0.987 0.013 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.986 0.014 0.000
M54.9 Dorsalgia, unspecified
0.986 0.014 0.000
T51 Toxic effect of alcohol
0.985 0.015 0.000
R47-R49 Symptoms and signs involving speech and voice
0.984 0.016 0.000
M79.8 Other specified soft tissue disorders
0.984 0.016 0.000
Chapter XXII Codes for special purposes
0.984 0.016 0.000
I08 Multiple valve diseases
0.984 0.016 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.984 0.016 0.000
M48.06 Spinal stenosis (Lumbar region)
0.983 0.017 0.000
T86 Failure and rejection of transplanted organs and tissues
0.983 0.017 0.000
Y40 Systemic antibiotics
0.983 0.017 0.000
S80-S89 Injuries to the knee and lower leg
0.983 0.017 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.982 0.018 0.000
Y43.3 Other antineoplastic drugs
0.982 0.018 0.000
S20-S29 Injuries to the thorax
0.982 0.018 0.000
Q60-Q64 Congenital malformations of the urinary system
0.982 0.018 0.000
D68 Other coagulation defects
0.981 0.019 0.000
J20-J22 Other acute lower respiratory infections
0.981 0.019 0.000
I24 Other acute ischaemic heart diseases
0.981 0.019 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.980 0.020 0.000
H10-H13 Disorders of conjunctiva
0.980 0.020 0.000
M65-M68 Disorders of synovium and tendon
0.979 0.021 0.000
M25.4 Effusion of joint
0.979 0.021 0.000
L50-L54 Urticaria and erythema
0.979 0.021 0.000
M51 Other intervertebral disk disorders
0.978 0.022 0.000
W00-W19 Falls
0.978 0.022 0.000
H30-H36 Disorders of choroid and retina
0.977 0.023 0.000
F33.9 Recurrent depressive disorder, unspecified
0.977 0.023 0.000
I85 Oesophageal varices
0.976 0.024 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.976 0.024 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.976 0.024 0.000
G93 Other disorders of brain
0.975 0.025 0.000
C78.7 Secondary malignant neoplasm of liver
0.975 0.025 0.000
G58 Other mononeuropathies
0.974 0.026 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.973 0.027 0.000
B37 Candidiasis
0.973 0.027 0.000
R59 Enlarged lymph nodes
0.973 0.027 0.000
M25.56 Pain in joint (Lower leg)
0.973 0.027 0.000
C51-C58 Malignant neoplasms of female genital organs
0.972 0.028 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.970 0.030 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.970 0.030 0.000
M24 Other specific joint derangements
0.970 0.030 0.000
H35 Other retinal disorders
0.969 0.031 0.000
Q61 Cystic kidney disease
0.969 0.031 0.000
M21 Other acquired deformities of limbs
0.968 0.032 0.000
M25.8 Other specified joint disorders
0.968 0.032 0.000
M07 Psoriatic and enteropathic arthropathies
0.968 0.032 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.968 0.032 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.967 0.033 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.967 0.033 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.966 0.034 0.000
M79.62 Pain in limb (Upper arm)
0.966 0.034 0.000
Z50.1 Other physical therapy
0.966 0.034 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.965 0.035 0.000
K74 Fibrosis and cirrhosis of liver
0.965 0.035 0.000
M31.6 Other giant cell arteritis
0.965 0.035 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.965 0.035 0.000
R21 Rash and other nonspecific skin eruption
0.964 0.036 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.964 0.036 0.000
C92 Myeloid leukaemia
0.964 0.036 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.964 0.036 0.000
M65 Synovitis and tenosynovitis
0.964 0.036 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.963 0.037 0.000
Z94.0 Kidney transplant status
0.963 0.037 0.000
J09-J18 Influenza and pneumonia
0.963 0.037 0.000
M50.3 Other cervical disk degeneration
0.963 0.037 0.000
T86.1 Kidney transplant failure and rejection
0.962 0.038 0.000
S70-S79 Injuries to the hip and thigh
0.962 0.038 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.962 0.038 0.000
H55-H59 Other disorders of eye and adnexa
0.962 0.038 0.000
L50 Urticaria
0.962 0.038 0.000
T51.0 Ethanol
0.962 0.038 0.000
Z51.8 Other specified medical care
0.961 0.039 0.000
M50.0 Cervical disk disorder with myelopathy
0.961 0.039 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.961 0.039 0.000
G40 Epilepsy
0.961 0.039 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.959 0.041 0.000
M86-M90 Other osteopathies
0.959 0.041 0.000
D47.1 Chronic myeloproliferative disease
0.959 0.041 0.000
Z81 Family history of mental and behavioural disorders
0.959 0.041 0.000
H11 Other disorders of conjunctiva
0.958 0.042 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.958 0.042 0.000
Z51.2 Other chemotherapy
0.958 0.042 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.957 0.043 0.000
I20 Angina pectoris
0.957 0.043 0.000
U80 Agent resistant to penicillin and related antibiotics
0.957 0.043 0.000
T66-T78 Other and unspecified effects of external causes
0.957 0.043 0.000
F80-F89 Disorders of psychological development
0.956 0.044 0.000
Z50.5 Speech therapy
0.956 0.044 0.000
M11 Other crystal arthropathies
0.956 0.044 0.000
Z43 Attention to artificial openings
0.956 0.044 0.000
O60-O75 Complications of labour and delivery
0.956 0.044 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.956 0.044 0.000
Z91.5 Personal history of self-harm
0.955 0.045 0.000
G30-G32 Other degenerative diseases of the nervous system
0.954 0.046 0.000
G44 Other headache syndromes
0.954 0.046 0.000
A00-A09 Intestinal infectious diseases
0.954 0.046 0.000
M84 Disorders of continuity of bone
0.953 0.047 0.000
Y40.8 Other systemic antibiotics
0.952 0.048 0.000
L40-L45 Papulosquamous disorders
0.952 0.048 0.000
M47.2 Other spondylosis with radiculopathy
0.952 0.048 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.952 0.048 0.000
M85 Other disorders of bone density and structure
0.951 0.049 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.951 0.049 0.000
T92 Sequelae of injuries of upper limb
0.951 0.049 0.000
M54.29 Cervicalgia-Site unspe
0.951 0.049 0.000
S40-S49 Injuries to the shoulder and upper arm
0.951 0.049 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.951 0.049 0.000
C79 Secondary malignant neoplasm of other sites
0.950 0.050 0.000
M19 Other arthrosis
0.950 0.050 0.000
R73 Elevated blood glucose level
0.950 0.050 0.000
I71 Aortic aneurysm and dissection
0.950 0.050 0.000
J00-J06 Acute upper respiratory infections
0.950 0.050 0.000
Z29 Need for other prophylactic measures
0.949 0.051 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.949 0.051 0.000
S90-S99 Injuries to the ankle and foot
0.948 0.052 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.948 0.052 0.000
I25.1 Atherosclerotic heart disease
0.948 0.052 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.947 0.053 0.000
M79.60 Pain in limb (Multiple sites)
0.946 0.054 0.000
F31 Bipolar affective disorder
0.946 0.054 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.945 0.055 0.000
I85.9 Oesophageal varices without bleeding
0.945 0.055 0.000
M07.3 Other psoriatic arthropathies
0.945 0.055 0.000
K74.3 Primary biliary cirrhosis
0.944 0.056 0.000
O47.0 False labour before 37 completed weeks of gestation
0.944 0.056 0.000
Z50.0 Cardiac rehabilitation
0.943 0.057 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.943 0.057 0.000
Z97 Presence of other devices
0.943 0.057 0.000
R57 Shock, not elsewhere classified
0.942 0.058 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.942 0.058 0.000
O46.9 Antepartum haemorrhage, unspecified
0.942 0.058 0.000
K65-K67 Diseases of peritoneum
0.941 0.059 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.941 0.059 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.940 0.060 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.940 0.060 0.000
C92.0 Acute myeloid leukaemia
0.940 0.060 0.000
J22 Unspecified acute lower respiratory infection
0.940 0.060 0.000
M51.2 Other specified intervertebral disk displacement
0.940 0.060 0.000
M17.1 Other primary gonarthrosis
0.939 0.061 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.938 0.062 0.000
S62.6 Fracture of other finger
0.938 0.062 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.937 0.063 0.000
I99 Other and unspecified disorders of circulatory system
0.936 0.064 0.000
M70.6 Trochanteric bursitis
0.936 0.064 0.000
J38.7 Other diseases of larynx
0.936 0.064 0.000
I80 Phlebitis and thrombophlebitis
0.935 0.065 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.935 0.065 0.000
C56 Malignant neoplasm of ovary
0.935 0.065 0.000
L50.9 Urticaria, unspecified
0.935 0.065 0.000
R47 Speech disturbances, not elsewhere classified
0.935 0.065 0.000
I72 Other aneurysm
0.934 0.066 0.000
M13 Other arthritis
0.934 0.066 0.000
J32.0 Chronic maxillary sinusitis
0.934 0.066 0.000
D60-D64 Aplastic and other anaemias
0.933 0.067 0.000
H35.9 Retinal disorder, unspecified
0.933 0.067 0.000
R59.0 Localised enlarged lymph nodes
0.932 0.068 0.000
Z81.8 Family history of other mental and behavioural disorders
0.932 0.068 0.000
I24.8 Other forms of acute ischaemic heart disease
0.932 0.068 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.932 0.068 0.000
C71 Malignant neoplasm of brain
0.932 0.068 0.000
Z94.8 Other transplanted organ and tissue status
0.931 0.069 0.000
I87 Other disorders of veins
0.931 0.069 0.000
M25.46 Effusion of joint (Lower leg)
0.931 0.069 0.000
U80.1 Methicillin resistant agent
0.931 0.069 0.000
B15-B19 Viral hepatitis
0.930 0.070 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.930 0.070 0.000
J35 Chronic diseases of tonsils and adenoids
0.930 0.070 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.930 0.070 0.000
W13 Fall from, out of or through building or structure
0.930 0.070 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.930 0.070 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.929 0.071 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.929 0.071 0.000
S89 Other and unspecified injuries of lower leg
0.929 0.071 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.929 0.071 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.928 0.072 0.000
I74.5 Embolism and thrombosis of iliac artery
0.928 0.072 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.928 0.072 0.000
B25-B34 Other viral diseases
0.927 0.073 0.000
B37.3 Candidiasis of vulva and vagina
0.926 0.074 0.000
R73.0 Abnormal glucose tolerance test
0.926 0.074 0.000
M46 Other inflammatory spondylopathies
0.926 0.074 0.000
M11.2 Other chondrocalcinosis
0.925 0.075 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.925 0.075 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.925 0.075 0.000
M54.1 Radiculopathy
0.924 0.076 0.000
R45 Symptoms and signs involving emotional state
0.924 0.076 0.000
L08 Other local infections of skin and subcutaneous tissue
0.923 0.077 0.000
J95-J99 Other diseases of the respiratory system
0.923 0.077 0.000
R49 Voice disturbances
0.921 0.079 0.000
Y57 Other and unspecified drugs and medicaments
0.921 0.079 0.000
G44.2 Tension-type headache
0.920 0.080 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.919 0.081 0.000
R23 Other skin changes
0.919 0.081 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.919 0.081 0.000
C80 Malignant neoplasm without specification of site
0.918 0.082 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.918 0.082 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.917 0.083 0.000
R52 Pain, not elsewhere classified
0.916 0.084 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.916 0.084 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.915 0.085 0.000
I77 Other disorders of arteries and arterioles
0.915 0.085 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.914 0.086 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.914 0.086 0.000
D47.2 Monoclonal gammopathy
0.914 0.086 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.913 0.087 0.000
A30-A49 Other bacterial diseases
0.912 0.088 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.912 0.088 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.911 0.089 0.000
G70-G73 Diseases of myoneural junction and muscle
0.911 0.089 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.910 0.090 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.909 0.091 0.000
D62 Acute posthaemorrhagic anaemia
0.909 0.091 0.000
S62.60 Fracture of other finger (closed)
0.909 0.091 0.000
Q61.2 Polycystic kidney, adult type
0.909 0.091 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.907 0.093 0.000
T51.9 Alcohol, unspecified
0.907 0.093 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.906 0.094 0.000
Q61.3 Polycystic kidney, unspecified
0.906 0.094 0.000
K11.5 Sialolithiasis
0.906 0.094 0.000
K66 Other disorders of peritoneum
0.905 0.095 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.904 0.096 0.000
Z83 Family history of other specific disorders
0.904 0.096 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.904 0.096 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.904 0.096 0.000
G58.9 Mononeuropathy, unspecified
0.904 0.096 0.000
Y43.4 Immunosuppressive agents
0.904 0.096 0.000
G95 Other diseases of spinal cord
0.904 0.096 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.904 0.096 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.904 0.096 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.902 0.098 0.000
R47.1 Dysarthria and anarthria
0.902 0.098 0.000
K12 Stomatitis and related lesions
0.902 0.098 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.902 0.098 0.000
I20.1 Angina pectoris with documented spasm
0.901 0.099 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.901 0.099 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.901 0.099 0.000
I25.5 Ischaemic cardiomyopathy
0.900 0.100 0.000
G58.8 Other specified mononeuropathies
0.900 0.100 0.000
S72 Fracture of femur
0.900 0.100 0.000
L20-L30 Dermatitis and eczema
0.900 0.100 0.000
K07 Dentofacial anomalies [including malocclusion]
0.900 0.100 0.000
K75 Other inflammatory liver diseases
0.899 0.101 0.000
T90 Sequelae of injuries of head
0.899 0.101 0.000
M89 Other disorders of bone
0.898 0.102 0.000
S50-S59 Injuries to the elbow and forearm
0.898 0.102 0.000
Z43.2 Attention to ileostomy
0.896 0.104 0.000
W13.9 Unspecified place
0.896 0.104 0.000
M22 Disorders of patella
0.894 0.106 0.000
M79.1 Myalgia
0.894 0.106 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.893 0.107 0.000
R54 Senility
0.893 0.107 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.892 0.108 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.892 0.108 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.891 0.109 0.000
S81 Open wound of lower leg
0.891 0.109 0.000
M05 Seropositive rheumatoid arthritis
0.891 0.109 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.891 0.109 0.000
M25.47 Effusion of joint (Ankle and foot)
0.891 0.109 0.000
C09 Malignant neoplasm of tonsil
0.891 0.109 0.000
S22.3 Fracture of rib
0.891 0.109 0.000
M25.71 Osteophyte (Shoulder region)
0.890 0.110 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.890 0.110 0.000
K10 Other diseases of jaws
0.890 0.110 0.000
S89.9 Unspecified injury of lower leg
0.890 0.110 0.000
T42.4 Benzodiazepines
0.890 0.110 0.000
Z35 Supervision of high-risk pregnancy
0.889 0.111 0.000
M25.74 Osteophyte (Hand)
0.889 0.111 0.000
M71 Other bursopathies
0.889 0.111 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.889 0.111 0.000
J20 Acute bronchitis
0.888 0.112 0.000
R76 Other abnormal immunological findings in serum
0.888 0.112 0.000
E20-E35 Disorders of other endocrine glands
0.887 0.113 0.000
R59.1 Generalised enlarged lymph nodes
0.887 0.113 0.000
M51.8 Other specified intervertebral disk disorders
0.887 0.113 0.000
R45.8 Other symptoms and signs involving emotional state
0.886 0.114 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.886 0.114 0.000
C77.0 Lymph nodes of head, face and neck
0.885 0.115 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.885 0.115 0.000
J06.9 Acute upper respiratory infection, unspecified
0.885 0.115 0.000
J32.4 Chronic pansinusitis
0.885 0.115 0.000
M91-M94 Chondropathies
0.884 0.116 0.000
H35.4 Peripheral retinal degeneration
0.884 0.116 0.000
I22 Subsequent myocardial infarction
0.884 0.116 0.000
F29 Unspecified nonorganic psychosis
0.883 0.117 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.883 0.117 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.883 0.117 0.000
S62.2 Fracture of first metacarpal bone
0.882 0.118 0.000
M79.7 Fibromyalgia
0.882 0.118 0.000
B37.0 Candidal stomatitis
0.882 0.118 0.000
G31.8 Other specified degenerative diseases of nervous system
0.881 0.119 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.881 0.119 0.000
I05 Rheumatic mitral valve diseases
0.881 0.119 0.000
S69 Other and unspecified injuries of wrist and hand
0.880 0.120 0.000
K11.2 Sialoadenitis
0.879 0.121 0.000
D37.5 Rectum
0.879 0.121 0.000
M24.0 Loose body in joint
0.879 0.121 0.000
L40 Psoriasis
0.878 0.122 0.000
J31.2 Chronic pharyngitis
0.878 0.122 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.878 0.122 0.000
Z57 Occupational exposure to risk-factors
0.878 0.122 0.000
R22.0 Localised swelling, mass and lump, head
0.877 0.123 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.877 0.123 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.877 0.123 0.000
T92.1 Sequelae of fracture of arm
0.876 0.124 0.000
F81 Specific developmental disorders of scholastic skills
0.876 0.124 0.000
Z22 Carrier of infectious disease
0.876 0.124 0.000
T78 Adverse effects, not elsewhere classified
0.875 0.125 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.875 0.125 0.000
J30 Vasomotor and allergic rhinitis
0.874 0.126 0.000
S63.6 Sprain and strain of finger(s)
0.874 0.126 0.000
A04 Other bacterial intestinal infections
0.874 0.126 0.000
J32.8 Other chronic sinusitis
0.873 0.127 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.873 0.127 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.873 0.127 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.872 0.128 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.871 0.129 0.000
S60 Superficial injury of wrist and hand
0.871 0.129 0.000
Z63 Other problems related to primary support group, including family circumstances
0.871 0.129 0.000
J18 Pneumonia, organism unspecified
0.871 0.129 0.000
M79.63 Pain in limb (Forearm)
0.870 0.130 0.000
G96 Other disorders of central nervous system
0.869 0.131 0.000
A80-A89 Viral infections of the central nervous system
0.869 0.131 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.869 0.131 0.000
M25.84 Other specified joint disorders (Hand)
0.868 0.132 0.000
K04 Diseases of pulp and periapical tissues
0.868 0.132 0.000
M21.0 Valgus deformity, not elsewhere classified
0.868 0.132 0.000
M31.3 Wegener's granulomatosis
0.868 0.132 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.868 0.132 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.866 0.134 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.866 0.134 0.000
F60-F69 Disorders of adult personality and behaviour
0.866 0.134 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.866 0.134 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.865 0.135 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.865 0.135 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.865 0.135 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.864 0.136 0.000
Y57.9 Drug or medicament, unspecified
0.864 0.136 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.864 0.136 0.000
I82 Other venous embolism and thrombosis
0.863 0.137 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.863 0.137 0.000
O41 Other disorders of amniotic fluid and membranes
0.862 0.138 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.862 0.138 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.862 0.138 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.862 0.138 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.862 0.138 0.000
Z97.4 Presence of external hearing-aid
0.862 0.138 0.000
J81 Pulmonary oedema
0.861 0.139 0.000
I20.0 Unstable angina
0.861 0.139 0.000
Chapter VIII Diseases of the ear and mastoid process
0.861 0.139 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.861 0.139 0.000
M19.1 Posttraumatic arthrosis of other joints
0.860 0.140 0.000
M24.1 Other articular cartilage disorders
0.860 0.140 0.000
K72 Hepatic failure, not elsewhere classified
0.860 0.140 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.860 0.140 0.000
H57 Other disorders of eye and adnexa
0.859 0.141 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.859 0.141 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.858 0.142 0.000
R49.0 Dysphonia
0.858 0.142 0.000
O43 Placental disorders
0.858 0.142 0.000
S22.30 Fracture of rib (closed)
0.857 0.143 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.857 0.143 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.857 0.143 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.856 0.144 0.000
B91 Sequelae of poliomyelitis
0.856 0.144 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.856 0.144 0.000
D68.9 Coagulation defect, unspecified
0.855 0.145 0.000
J39 Other diseases of upper respiratory tract
0.855 0.145 0.000
C71.2 Temporal lobe
0.854 0.146 0.000
M22.4 Chondromalacia patellae
0.854 0.146 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.854 0.146 0.000
T68 Hypothermia
0.853 0.147 0.000
H35.7 Separation of retinal layers
0.853 0.147 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.852 0.148 0.000
C09.9 Tonsil, unspecified
0.851 0.149 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.851 0.149 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.851 0.149 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.851 0.149 0.000
F80 Specific developmental disorders of speech and language
0.851 0.149 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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