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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79156452
log Bayes Factor = 15.6605
Chromosome 3   position 188,651,313  (GRCh37) Explore rs79156452 on Ensembl!
Variant rs79156452 is part of Cluster X0143

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.995 0.005 0.000
M25 Other joint disorders, not elsewhere classified
0.994 0.006 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.991 0.009 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.989 0.011 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.983 0.017 0.000
R10 Abdominal and pelvic pain
0.982 0.018 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.973 0.027 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.972 0.028 0.000
R42 Dizziness and giddiness
0.970 0.030 0.000
I84 Haemorrhoids
0.968 0.032 0.000
R47-R49 Symptoms and signs involving speech and voice
0.964 0.036 0.000
M15-M19 Arthrosis
0.960 0.040 0.000
Chapter XX External causes of morbidity and mortality
0.960 0.040 0.000
I51 Complications and ill-defined descriptions of heart disease
0.958 0.042 0.000
I84.8 Unspecified haemorrhoids with other complications
0.953 0.047 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.952 0.048 0.000
M05-M14 Inflammatory polyarthropathies
0.951 0.049 0.000
J20-J22 Other acute lower respiratory infections
0.950 0.050 0.000
M17 Gonarthrosis [arthrosis of knee]
0.949 0.051 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.949 0.051 0.000
R10.3 Pain localised to other parts of lower abdomen
0.947 0.053 0.000
J90-J94 Other diseases of pleura
0.947 0.053 0.000
I49 Other cardiac arrhythmias
0.947 0.053 0.000
I51.7 Cardiomegaly
0.944 0.056 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.942 0.058 0.000
O60-O75 Complications of labour and delivery
0.942 0.058 0.000
M25.7 Osteophyte
0.940 0.060 0.000
R11 Nausea and vomiting
0.937 0.063 0.000
R10.2 Pelvic and perineal pain
0.930 0.070 0.000
J30-J39 Other diseases of upper respiratory tract
0.929 0.071 0.000
R47 Speech disturbances, not elsewhere classified
0.924 0.076 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.924 0.076 0.000
Chapter V Mental and behavioural disorders
0.922 0.078 0.000
M25.5 Pain in joint
0.921 0.079 0.000
J22 Unspecified acute lower respiratory infection
0.916 0.084 0.000
M17.9 Gonarthrosis, unspecified
0.915 0.085 0.000
M13 Other arthritis
0.910 0.090 0.000
L82 Seborrhoeic keratosis
0.909 0.091 0.000
R18 Ascites
0.908 0.092 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.899 0.101 0.000
M24 Other specific joint derangements
0.898 0.102 0.000
M25.77 Osteophyte (Ankle and foot)
0.898 0.102 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.897 0.103 0.000
I85 Oesophageal varices
0.896 0.104 0.000
G90-G99 Other disorders of the nervous system
0.895 0.105 0.000
J90 Pleural effusion, not elsewhere classified
0.894 0.106 0.000
M23 Internal derangement of knee
0.884 0.116 0.000
J09-J18 Influenza and pneumonia
0.884 0.116 0.000
O48 Prolonged pregnancy
0.883 0.117 0.000
J32 Chronic sinusitis
0.882 0.118 0.000
M13.9 Arthritis, unspecified
0.882 0.118 0.000
I31 Other diseases of pericardium
0.881 0.119 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.878 0.122 0.000
O47 False labour
0.875 0.125 0.000
R47.8 Other and unspecified speech disturbances
0.871 0.129 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.869 0.131 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.869 0.131 0.000
R21 Rash and other nonspecific skin eruption
0.866 0.134 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.864 0.136 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.863 0.137 0.000
I38 Endocarditis, valve unspecified
0.861 0.139 0.000
M17.1 Other primary gonarthrosis
0.860 0.140 0.000
M65-M68 Disorders of synovium and tendon
0.860 0.140 0.000
R20 Disturbances of skin sensation
0.858 0.142 0.000
M50-M54 Other dorsopathies
0.855 0.145 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.852 0.148 0.000
I49.3 Ventricular premature depolarisation
0.850 0.150 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.844 0.156 0.000
M20 Acquired deformities of fingers and toes
0.840 0.160 0.000
Chapter I Certain infectious and parasitic diseases
0.840 0.160 0.000
O72 Postpartum haemorrhage
0.838 0.162 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.838 0.162 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.837 0.163 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.835 0.165 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.829 0.171 0.000
I05-I09 Chronic rheumatic heart diseases
0.828 0.172 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.827 0.173 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.821 0.179 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.821 0.179 0.000
I80 Phlebitis and thrombophlebitis
0.821 0.179 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.820 0.180 0.000
M31 Other necrotising vasculopathies
0.820 0.180 0.000
R10.4 Other and unspecified abdominal pain
0.818 0.182 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.817 0.183 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.814 0.186 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.813 0.187 0.000
M25.56 Pain in joint (Lower leg)
0.811 0.189 0.000
M25.4 Effusion of joint
0.811 0.189 0.000
R45 Symptoms and signs involving emotional state
0.811 0.189 0.000
F30-F39 Mood [affective] disorders
0.811 0.189 0.000
I84.4 External haemorrhoids with other complications
0.808 0.192 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.805 0.195 0.000
I85.9 Oesophageal varices without bleeding
0.804 0.196 0.000
J60-J70 Lung diseases due to external agents
0.803 0.197 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.801 0.199 0.000
W00-W19 Falls
0.801 0.199 0.000
J32.0 Chronic maxillary sinusitis
0.800 0.200 0.000
M25.9 Joint disorder, unspecified
0.798 0.202 0.000
G56 Mononeuropathies of upper limb
0.797 0.203 0.000
S60-S69 Injuries to the wrist and hand
0.796 0.204 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.795 0.205 0.000
G30-G32 Other degenerative diseases of the nervous system
0.795 0.205 0.000
F80-F89 Disorders of psychological development
0.794 0.206 0.000
I84.6 Residual haemorrhoidal skin tags
0.794 0.206 0.000
I84.1 Internal haemorrhoids with other complications
0.794 0.206 0.000
M20.5 Other deformities of toe(s) (acquired)
0.792 0.208 0.000
R40 Somnolence, stupor and coma
0.791 0.209 0.000
M11 Other crystal arthropathies
0.791 0.209 0.000
R49 Voice disturbances
0.788 0.212 0.000
I49.8 Other specified cardiac arrhythmias
0.786 0.214 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.785 0.215 0.000
I30 Acute pericarditis
0.785 0.215 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.785 0.215 0.000
M80-M85 Disorders of bone density and structure
0.784 0.216 0.000
M25.51 Pain in joint (Shoulder region)
0.784 0.216 0.000
I84.3 External thrombosed haemorrhoids
0.782 0.218 0.000
R16.1 Splenomegaly, not elsewhere classified
0.782 0.218 0.000
J32.9 Chronic sinusitis, unspecified
0.781 0.219 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.780 0.220 0.000
O34.1 Maternal care for tumour of corpus uteri
0.780 0.220 0.000
O44 Placenta praevia
0.777 0.223 0.000
R27 Other lack of coordination
0.777 0.223 0.000
S70-S79 Injuries to the hip and thigh
0.775 0.225 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.775 0.225 0.000
I86 Varicose veins of other sites
0.773 0.227 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.772 0.228 0.000
T66-T78 Other and unspecified effects of external causes
0.772 0.228 0.000
S90-S99 Injuries to the ankle and foot
0.770 0.230 0.000
O42 Premature rupture of membranes
0.769 0.231 0.000
M25.8 Other specified joint disorders
0.768 0.232 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.768 0.232 0.000
S50-S59 Injuries to the elbow and forearm
0.766 0.234 0.000
M86-M90 Other osteopathies
0.765 0.235 0.000
J91 Pleural effusion in conditions classified elsewhere
0.765 0.235 0.000
M25.0 Haemarthrosis
0.765 0.235 0.000
I31.3 Pericardial effusion (noninflammatory)
0.764 0.236 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.763 0.237 0.000
J95-J99 Other diseases of the respiratory system
0.763 0.237 0.000
J18 Pneumonia, organism unspecified
0.762 0.238 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.762 0.238 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.762 0.238 0.000
G56.0 Carpal tunnel syndrome
0.761 0.239 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.761 0.239 0.000
M17.0 Primary gonarthrosis, bilateral
0.760 0.240 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.759 0.241 0.000
O40 Polyhydramnios
0.759 0.241 0.000
L60-L75 Disorders of skin appendages
0.759 0.241 0.000
M21 Other acquired deformities of limbs
0.758 0.242 0.000
G93 Other disorders of brain
0.756 0.244 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.756 0.244 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.754 0.246 0.000
J94 Other pleural conditions
0.753 0.247 0.000
I49.4 Other and unspecified premature depolarisation
0.753 0.247 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.752 0.248 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.751 0.248 0.000
M13.94 Arthritis, unspecified (Hand)
0.751 0.249 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.751 0.249 0.000
M34 Systemic sclerosis
0.751 0.249 0.000
M24.1 Other articular cartilage disorders
0.750 0.250 0.000
I47 Paroxysmal tachycardia
0.750 0.250 0.000
I49.9 Cardiac arrhythmia, unspecified
0.749 0.251 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.749 0.251 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.749 0.251 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.749 0.251 0.000
W50-W64 Exposure to animate mechanical forces
0.747 0.252 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.745 0.255 0.000
G95 Other diseases of spinal cord
0.745 0.255 0.000
M00-M03 Infectious arthropathies
0.743 0.257 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.742 0.258 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.742 0.258 0.000
O70 Perineal laceration during delivery
0.740 0.260 0.000
J35 Chronic diseases of tonsils and adenoids
0.740 0.260 0.000
R10.0 Acute abdomen
0.739 0.261 0.000
L91 Hypertrophic disorders of skin
0.738 0.262 0.000
R47.1 Dysarthria and anarthria
0.738 0.262 0.000
F99-F99 Unspecified mental disorder
0.738 0.262 0.000
M54 Dorsalgia
0.738 0.262 0.000
I33 Acute and subacute endocarditis
0.736 0.264 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.736 0.264 0.000
M40-M43 Deforming dorsopathies
0.736 0.264 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.736 0.264 0.000
I87 Other disorders of veins
0.736 0.264 0.000
J18.1 Lobar pneumonia, unspecified
0.735 0.265 0.000
O62 Abnormalities of forces of labour
0.734 0.265 0.000
S40-S49 Injuries to the shoulder and upper arm
0.733 0.267 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.731 0.269 0.000
M24.0 Loose body in joint
0.731 0.269 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.730 0.270 0.000
O80-O84 Delivery
0.729 0.270 0.000
M65 Synovitis and tenosynovitis
0.727 0.273 0.000
R47.0 Dysphasia and aphasia
0.725 0.275 0.000
M70-M79 Other soft tissue disorders
0.725 0.275 0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.724 0.276 0.000
G51 Facial nerve disorders
0.723 0.277 0.000
O41 Other disorders of amniotic fluid and membranes
0.723 0.277 0.000
I08 Multiple valve diseases
0.723 0.277 0.000
I81 Portal vein thrombosis
0.720 0.279 0.000
M25.74 Osteophyte (Hand)
0.720 0.280 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.719 0.281 0.000
I84.0 Internal thrombosed haemorrhoids
0.718 0.282 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.283 0.000
M33 Dermatopolymyositis
0.716 0.283 0.000
M32 Systemic lupus erythematosus
0.716 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.283 0.000
I85.0 Oesophageal varices with bleeding
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
J92 Pleural plaque
0.715 0.285 0.000
M25.78 Osteophyte (Other)
0.715 0.285 0.000
I31.9 Disease of pericardium, unspecified
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
O45 Premature separation of placenta [abruptio placentae]
0.714 0.286 0.000
O43 Placental disorders
0.714 0.286 0.000
O33 Maternal care for known or suspected disproportion
0.714 0.286 0.000
O31 Complications specific to multiple gestation
0.714 0.286 0.000
M31.3 Wegener's granulomatosis
0.713 0.287 0.000
M25.3 Other instability of joint
0.713 0.287 0.000
M25.2 Flail joint
0.713 0.287 0.000
M25.1 Fistula of joint
0.713 0.287 0.000
J00-J06 Acute upper respiratory infections
0.713 0.287 0.000
M25.71 Osteophyte (Shoulder region)
0.712 0.288 0.000
M25.59 Pain in joint (Site unspecified)
0.710 0.290 0.000
M07 Psoriatic and enteropathic arthropathies
0.710 0.290 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
J37 Chronic laryngitis and laryngotracheitis
0.709 0.291 0.000
R46 Symptoms and signs involving appearance and behaviour
0.709 0.291 0.000
R43 Disturbances of smell and taste
0.709 0.291 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
I88 Nonspecific lymphadenitis
0.708 0.292 0.000
I49.0 Ventricular fibrillation and flutter
0.708 0.292 0.000
I27 Other pulmonary heart diseases
0.707 0.293 0.000
L93 Lupus erythematosus
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.706 0.294 0.000
G70-G73 Diseases of myoneural junction and muscle
0.705 0.295 0.000
O61 Failed induction of labour
0.704 0.296 0.000
F32 Depressive episode
0.704 0.296 0.000
G96 Other disorders of central nervous system
0.702 0.297 0.000
R45.1 Restlessness and agitation
0.702 0.298 0.000
B35-B49 Mycoses
0.702 0.298 0.000
O72.1 Other immediate postpartum haemorrhage
0.701 0.299 0.000
R50-R69 General symptoms and signs
0.701 0.299 0.000
J38.3 Other diseases of vocal cords
0.699 0.301 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.699 0.301 0.000
T33-T35 Frostbite
0.698 0.302 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.698 0.302 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.698 0.302 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.698 0.302 0.000
T00-T07 Injuries involving multiple body regions
0.698 0.302 0.000
S10-S19 Injuries to the neck
0.698 0.302 0.000
L10-L14 Bullous disorders
0.697 0.303 0.000
R23 Other skin changes
0.695 0.305 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
G35 Multiple sclerosis
0.694 0.306 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.692 0.308 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.691 0.309 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.691 0.309 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.690 0.310 0.000
F80 Specific developmental disorders of speech and language
0.690 0.310 0.000
O47.0 False labour before 37 completed weeks of gestation
0.690 0.310 0.000
M25.46 Effusion of joint (Lower leg)
0.689 0.311 0.000
R27.8 Other and unspecified lack of coordination
0.689 0.311 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.689 0.311 0.000
O00-O08 Pregnancy with abortive outcome
0.689 0.311 0.000
M15 Polyarthrosis
0.688 0.311 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.688 0.312 0.000
G91 Hydrocephalus
0.688 0.312 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.688 0.312 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.688 0.312 0.000
Y35-Y36 Legal intervention and operations of war
0.688 0.312 0.000
Y10-Y34 Event of undetermined intent
0.688 0.312 0.000
Y00-Y09 Assault
0.688 0.312 0.000
X85-X99 Assault
0.688 0.312 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.688 0.312 0.000
X50-X57 Overexertion, travel and privation
0.688 0.312 0.000
X30-X39 Exposure to forces of nature
0.688 0.312 0.000
X20-X29 Contact with venomous animals and plants
0.688 0.312 0.000
X10-X19 Contact with heat and hot substances
0.688 0.312 0.000
X00-X09 Exposure to smoke, fire and flames
0.688 0.312 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.688 0.312 0.000
W75-W84 Other accidental threats to breathing
0.688 0.312 0.000
W65-W74 Accidental drowning and submersion
0.688 0.312 0.000
V98-V99 Other and unspecified transport accidents
0.688 0.312 0.000
V95-V97 Air and space transport accidents
0.688 0.312 0.000
V90-V94 Water transport accidents
0.688 0.312 0.000
V80-V89 Other land transport accidents
0.688 0.312 0.000
V70-V79 Bus occupant injured in transport accident
0.688 0.312 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.688 0.312 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.688 0.312 0.000
V40-V49 Car occupant injured in transport accident
0.688 0.312 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.688 0.312 0.000
V01-V09 Pedestrian injured in transport accident
0.688 0.312 0.000
J31.0 Chronic rhinitis
0.688 0.312 0.000
I45 Other conduction disorders
0.687 0.312 0.000
F60-F69 Disorders of adult personality and behaviour
0.687 0.313 0.000
M05 Seropositive rheumatoid arthritis
0.687 0.313 0.000
I51.6 Cardiovascular disease, unspecified
0.687 0.313 0.000
I51.5 Myocardial degeneration
0.687 0.313 0.000
I51.4 Myocarditis, unspecified
0.687 0.313 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.687 0.313 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.687 0.313 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.687 0.313 0.000
I51.0 Cardiac septal defect, acquired
0.687 0.313 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.687 0.313 0.000
I84.5 External haemorrhoids without complication
0.685 0.315 0.000
Y43 Primarily systemic agents
0.683 0.317 0.000
O64.1 Obstructed labour due to breech presentation
0.683 0.317 0.000
L03 Cellulitis
0.682 0.318 0.000
M14 Arthropathies in other diseases classified elsewhere
0.681 0.318 0.000
M12 Other specific arthropathies
0.681 0.318 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.681 0.318 0.000
M08 Juvenile arthritis
0.681 0.318 0.000
J21 Acute bronchiolitis
0.681 0.318 0.000
J20 Acute bronchitis
0.681 0.318 0.000
M17.5 Other secondary gonarthrosis
0.681 0.319 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.681 0.319 0.000
M17.3 Other posttraumatic gonarthrosis
0.681 0.319 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.681 0.319 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.680 0.319 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.680 0.319 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.680 0.319 0.000
O34.6 Maternal care for abnormality of vagina
0.680 0.319 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.680 0.319 0.000
O34.4 Maternal care for other abnormalities of cervix
0.680 0.319 0.000
O34.3 Maternal care for cervical incompetence
0.680 0.319 0.000
O34.0 Maternal care for congenital malformation of uterus
0.680 0.319 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.679 0.321 0.000
I49.2 Junctional premature depolarisation
0.679 0.321 0.000
I49.1 Atrial premature depolarisation
0.679 0.321 0.000
M23.8 Other internal derangements of knee
0.678 0.322 0.000
S32 Fracture of lumbar spine and pelvis
0.678 0.322 0.000
M45-M49 Spondylopathies
0.678 0.322 0.000
L81 Other disorders of pigmentation
0.678 0.322 0.000
M11.2 Other chondrocalcinosis
0.677 0.323 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.677 0.323 0.000
J81 Pulmonary oedema
0.676 0.324 0.000
M67 Other disorders of synovium and tendon
0.676 0.324 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.676 0.324 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.676 0.324 0.000
L94 Other localised connective tissue disorders
0.676 0.324 0.000
L87 Transepidermal elimination disorders
0.676 0.324 0.000
L88 Pyoderma gangrenosum
0.676 0.324 0.000
L86 Keratoderma in diseases classified elsewhere
0.676 0.324 0.000
L83 Acanthosis nigricans
0.676 0.324 0.000
L80 Vitiligo
0.676 0.324 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.675 0.325 0.000
V20-V29 Motorcycle rider injured in transport accident
0.675 0.325 0.000
O74 Complications of anaesthesia during labour and delivery
0.675 0.325 0.000
O73 Retained placenta and membranes, without haemorrhage
0.675 0.325 0.000
O71 Other obstetric trauma
0.675 0.325 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.675 0.325 0.000
O66 Other obstructed labour
0.675 0.325 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.675 0.325 0.000
O60 Preterm delivery
0.675 0.325 0.000
B15-B19 Viral hepatitis
0.674 0.326 0.000
M25.79 Osteophyte (Site unspecified)
0.674 0.326 0.000
M25.73 Osteophyte (Forearm)
0.674 0.326 0.000
M25.72 Osteophyte (Upper arm)
0.674 0.326 0.000
M25.70 Osteophyte (Multiple sites)
0.674 0.326 0.000
L85 Other epidermal thickening
0.674 0.326 0.000
L50-L54 Urticaria and erythema
0.673 0.326 0.000
Chapter XXII Codes for special purposes
0.673 0.327 0.000
M23.4 Loose body in knee
0.672 0.327 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.672 0.328 0.000
M20.0 Deformity of finger(s)
0.671 0.328 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.671 0.329 0.000
A00-A09 Intestinal infectious diseases
0.670 0.330 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.670 0.330 0.000
L84 Corns and callosities
0.670 0.330 0.000
O47.9 False labour, unspecified
0.669 0.330 0.000
O36 Maternal care for other known or suspected foetal problems
0.669 0.331 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.668 0.332 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.668 0.332 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.666 0.334 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.666 0.334 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.665 0.335 0.000
J31.2 Chronic pharyngitis
0.665 0.335 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.665 0.335 0.000
X60-X84 Intentional self-harm
0.665 0.335 0.000
J10 Influenza due to identified influenza virus
0.664 0.336 0.000
G58 Other mononeuropathies
0.662 0.338 0.000
G54 Nerve root and plexus disorders
0.662 0.338 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.662 0.338 0.000
G52 Disorders of other cranial nerves
0.662 0.338 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.662 0.338 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.661 0.338 0.000
F70-F79 Mental retardation
0.661 0.338 0.000
L57.0 Actinic keratosis
0.661 0.339 0.000
O30 Multiple gestation
0.661 0.339 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.660 0.340 0.000
M25.58 Pain in joint (Other)
0.660 0.340 0.000
M25.52 Pain in joint (Upper arm)
0.660 0.340 0.000
I51.9 Heart disease, unspecified
0.660 0.340 0.000
Y57 Other and unspecified drugs and medicaments
0.659 0.341 0.000
R20.2 Paraesthesia of skin
0.658 0.342 0.000
L60 Nail disorders
0.658 0.342 0.000
Chapter VIII Diseases of the ear and mastoid process
0.658 0.342 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.658 0.342 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.657 0.343 0.000
L20-L30 Dermatitis and eczema
0.656 0.344 0.000
O72.0 Third-stage haemorrhage
0.656 0.344 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.656 0.344 0.000
A80-A89 Viral infections of the central nervous system
0.655 0.345 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.654 0.346 0.000
M13.0 Polyarthritis, unspecified
0.653 0.347 0.000
Y85 Sequelae of transport accidents
0.653 0.347 0.000
M13.8 Other specified arthritis
0.653 0.347 0.000
M13.1 Monoarthritis, not elsewhere classified
0.653 0.347 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.652 0.348 0.000
I49.5 Sick sinus syndrome
0.652 0.348 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.652 0.348 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.651 0.349 0.000
I82 Other venous embolism and thrombosis
0.650 0.350 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.649 0.351 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.649 0.351 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.648 0.352 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.648 0.352 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.647 0.353 0.000
Y42.5 Other oestrogens and progestogens
0.647 0.353 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.645 0.355 0.000
O97 Death from sequelae of direct obstetric causes
0.645 0.355 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.645 0.355 0.000
O95 Obstetric death of unspecified cause
0.645 0.355 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.645 0.355 0.000
M24.9 Joint derangement, unspecified
0.644 0.356 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.644 0.356 0.000
M24.7 Protrusio acetabuli
0.644 0.356 0.000
M24.6 Ankylosis of joint
0.644 0.356 0.000
M24.5 Contracture of joint
0.644 0.356 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.644 0.356 0.000
M24.2 Disorder of ligament
0.644 0.356 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.644 0.356 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.644 0.356 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.642 0.358 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.642 0.358 0.000
G90 Disorders of autonomic nervous system
0.642 0.358 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.642 0.358 0.000
G92 Toxic encephalopathy
0.642 0.358 0.000
S20-S29 Injuries to the thorax
0.642 0.358 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.641 0.359 0.000
R80 Isolated proteinuria
0.640 0.360 0.000
I30.9 Acute pericarditis, unspecified
0.639 0.361 0.000
M50 Cervical disk disorders
0.638 0.362 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.638 0.362 0.000
B25-B34 Other viral diseases
0.638 0.362 0.000
G40-G47 Episodic and paroxysmal disorders
0.637 0.363 0.000
Y52 Agents primarily affecting the cardiovascular system
0.636 0.363 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.635 0.365 0.000
V10-V19 Pedal cyclist injured in transport accident
0.635 0.365 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.634 0.366 0.000
M23.9 Internal derangement of knee, unspecified
0.634 0.366 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.634 0.366 0.000
M23.5 Chronic instability of knee
0.634 0.366 0.000
M23.1 Discoid meniscus (congenital)
0.634 0.366 0.000
M23.0 Cystic meniscus
0.634 0.366 0.000
R82 Other abnormal findings in urine
0.634 0.366 0.000
I86.8 Varicose veins of other specified sites
0.634 0.366 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.634 0.366 0.000
J17 Pneumonia in diseases classified elsewhere
0.634 0.366 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.634 0.366 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.634 0.366 0.000
J12 Viral pneumonia, not elsewhere classified
0.634 0.366 0.000
J11 Influenza, virus not identified
0.634 0.366 0.000
J14 Pneumonia due to Haemophilus influenzae
0.634 0.366 0.000
J09 Influenza due to certain identified influenza virus
0.634 0.366 0.000
I95 Hypotension
0.634 0.366 0.000
R40.0 Somnolence
0.634 0.366 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.633 0.367 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.633 0.367 0.000
L90 Atrophic disorders of skin
0.633 0.367 0.000
W19 Unspecified fall
0.633 0.367 0.000
J32.8 Other chronic sinusitis
0.632 0.367 0.000
J32.4 Chronic pansinusitis
0.632 0.367 0.000
J32.3 Chronic sphenoidal sinusitis
0.632 0.367 0.000
J32.2 Chronic ethmoidal sinusitis
0.632 0.367 0.000
J32.1 Chronic frontal sinusitis
0.632 0.367 0.000
M13.93 Arthritis, unspecified (Forearm)
0.632 0.368 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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