TreeWAS – Variant ID: rs115717162

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001
I20-I25 Ischaemic heart diseases	0.998	0.002
M20-M25 Other joint disorders	0.997	0.003
J30-J39 Other diseases of upper respiratory tract	0.996	0.004
M05-M14 Inflammatory polyarthropathies	0.989	0.011
Chapter I Certain infectious and parasitic diseases	0.986	0.014
Chapter VI Diseases of the nervous system	0.982	0.018
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.982	0.018
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.981	0.019
R91 Abnormal findings on diagnostic imaging of lung	0.967	0.033
I10-I15 Hypertensive diseases	0.966	0.034
M23 Internal derangement of knee	0.963	0.037
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.962	0.038
M50-M54 Other dorsopathies	0.960	0.040
G50-G59 Nerve, nerve root and plexus disorders	0.960	0.040
J09-J18 Influenza and pneumonia	0.951	0.049
I10 Essential (primary) hypertension	0.949	0.051
R50-R69 General symptoms and signs	0.942	0.058
B95-B98 Bacterial, viral and other infectious agents	0.939	0.061
J31.0 Chronic rhinitis	0.938	0.062
I22 Subsequent myocardial infarction	0.937	0.063
S00-S09 Injuries to the head	0.936	0.064
I21 Acute myocardial infarction	0.935	0.065
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.933	0.067
M65-M68 Disorders of synovium and tendon	0.932	0.068
I20 Angina pectoris	0.927	0.073
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.926	0.074
Chapter XII Diseases of the skin and subcutaneous tissue	0.924	0.076
M06 Other rheumatoid arthritis	0.919	0.081
R47-R49 Symptoms and signs involving speech and voice	0.918	0.082
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.916	0.084
M23.2 Derangement of meniscus due to old tear or injury	0.916	0.084
M13 Other arthritis	0.915	0.085
G56 Mononeuropathies of upper limb	0.914	0.086
J18 Pneumonia, organism unspecified	0.911	0.089
M25 Other joint disorders, not elsewhere classified	0.909	0.091
B25-B34 Other viral diseases	0.907	0.093
J95-J99 Other diseases of the respiratory system	0.899	0.101
J36 Peritonsillar abscess	0.896	0.104
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.893	0.107
M65 Synovitis and tenosynovitis	0.892	0.108
M70-M79 Other soft tissue disorders	0.888	0.112
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.887	0.113
R59 Enlarged lymph nodes	0.886	0.114
B35-B49 Mycoses	0.886	0.114
G56.0 Carpal tunnel syndrome	0.885	0.115
R63 Symptoms and signs concerning food and fluid intake	0.885	0.115
M80-M85 Disorders of bone density and structure	0.884	0.116
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.878	0.122
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.872	0.128
R25 Abnormal involuntary movements	0.871	0.129
Chapter IV Endocrine, nutritional and metabolic diseases	0.864	0.136
I25 Chronic ischaemic heart disease	0.864	0.136
M50 Cervical disk disorders	0.864	0.136
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.864	0.136
R53 Malaise and fatigue	0.859	0.141
M10 Gout	0.859	0.141
I05-I09 Chronic rheumatic heart diseases	0.858	0.142
R63.4 Abnormal weight loss	0.857	0.143
J40-J47 Chronic lower respiratory diseases	0.854	0.146
Chapter VII Diseases of the eye and adnexa	0.853	0.147
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.852	0.148
B34 Viral infection of unspecified site	0.851	0.149
J18.9 Pneumonia, unspecified	0.849	0.151
M65.9 Synovitis and tenosynovitis, unspecified	0.849	0.151
M20 Acquired deformities of fingers and toes	0.846	0.154
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.845	0.155
I22.9 Subsequent myocardial infarction of unspecified site	0.843	0.157
M06.9 Rheumatoid arthritis, unspecified	0.841	0.159
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.840	0.160
J35 Chronic diseases of tonsils and adenoids	0.838	0.162
L40-L45 Papulosquamous disorders	0.838	0.162
I20.8 Other forms of angina pectoris	0.838	0.162
M13.9 Arthritis, unspecified	0.838	0.162
M23.8 Other internal derangements of knee	0.833	0.167
M54 Dorsalgia	0.830	0.170
I20.9 Angina pectoris, unspecified	0.830	0.170
L20-L30 Dermatitis and eczema	0.829	0.171
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.827	0.173
J98 Other respiratory disorders	0.827	0.173
J30 Vasomotor and allergic rhinitis	0.825	0.175
R49 Voice disturbances	0.824	0.176
I21.2 Acute transmural myocardial infarction of other sites	0.823	0.177
R79 Other abnormal findings of blood chemistry	0.823	0.177
M20.1 Hallux valgus (acquired)	0.821	0.179
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.820	0.180
M31 Other necrotising vasculopathies	0.820	0.180
I21.9 Acute myocardial infarction, unspecified	0.820	0.180
J33 Nasal polyp	0.819	0.181
I21.1 Acute transmural myocardial infarction of inferior wall	0.818	0.182
G90-G99 Other disorders of the nervous system	0.816	0.184
J80-J84 Other respiratory diseases principally affecting the interstitium	0.813	0.187
S10-S19 Injuries to the neck	0.810	0.189
B34.9 Viral infection, unspecified	0.810	0.190
R13 Dysphagia	0.808	0.192
M25.5 Pain in joint	0.805	0.195
I25.1 Atherosclerotic heart disease	0.805	0.195
B37 Candidiasis	0.800	0.200
G70-G73 Diseases of myoneural junction and muscle	0.800	0.200
J18.1 Lobar pneumonia, unspecified	0.799	0.201
R76 Other abnormal immunological findings in serum	0.798	0.202
S02 Fracture of skull and facial bones	0.798	0.202
R93 Abnormal findings on diagnostic imaging of other body structures	0.796	0.204
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.795	0.204
I26 Pulmonary embolism	0.795	0.205
R25.1 Tremor, unspecified	0.794	0.206
M45-M49 Spondylopathies	0.794	0.206
M13.99 Arthritis, unspecified (Site unspecified)	0.792	0.208
M51 Other intervertebral disk disorders	0.791	0.209
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.791	0.209
I60-I69 Cerebrovascular diseases	0.789	0.211
R57 Shock, not elsewhere classified	0.788	0.212
R59.1 Generalised enlarged lymph nodes	0.787	0.213
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.786	0.214
S06 Intracranial injury	0.785	0.215
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.783	0.217
Chapter VIII Diseases of the ear and mastoid process	0.783	0.217
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.781	0.219
J34 Other disorders of nose and nasal sinuses	0.780	0.220
I22.8 Subsequent myocardial infarction of other sites	0.779	0.221
S09 Other and unspecified injuries of head	0.778	0.222
R17 Unspecified jaundice	0.777	0.223
S00 Superficial injury of head	0.776	0.224
E00-E07 Disorders of thyroid gland	0.772	0.228
M24 Other specific joint derangements	0.771	0.229
R54 Senility	0.770	0.230
S40-S49 Injuries to the shoulder and upper arm	0.770	0.230
G35-G37 Demyelinating diseases of the central nervous system	0.769	0.231
G58 Other mononeuropathies	0.768	0.232
I24 Other acute ischaemic heart diseases	0.768	0.232
M21 Other acquired deformities of limbs	0.767	0.233
M79 Other soft tissue disorders, not elsewhere classified	0.767	0.233
M10.9 Gout, unspecified	0.766	0.234
M23.6 Other spontaneous disruption of ligament(s) of knee	0.763	0.237
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.762	0.238
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.762	0.238
H55-H59 Other disorders of eye and adnexa	0.762	0.238
M50.0 Cervical disk disorder with myelopathy	0.759	0.241
R49.0 Dysphonia	0.757	0.243
M81 Osteoporosis without pathological fracture	0.756	0.244
S70-S79 Injuries to the hip and thigh	0.755	0.245
M35 Other systemic involvement of connective tissue	0.755	0.245
R47 Speech disturbances, not elsewhere classified	0.754	0.246
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.754	0.246
I08 Multiple valve diseases	0.752	0.248
M06.0 Seronegative rheumatoid arthritis	0.751	0.249
T51 Toxic effect of alcohol	0.747	0.253
R59.0 Localised enlarged lymph nodes	0.745	0.255
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.745	0.255
R20 Disturbances of skin sensation	0.744	0.256
M25.7 Osteophyte	0.744	0.256
S20-S29 Injuries to the thorax	0.742	0.257
G40-G47 Episodic and paroxysmal disorders	0.740	0.260
M91-M94 Chondropathies	0.739	0.261
Chapter XX External causes of morbidity and mortality	0.739	0.261
M07 Psoriatic and enteropathic arthropathies	0.738	0.262
R68 Other general symptoms and signs	0.737	0.263
M13.0 Polyarthritis, unspecified	0.737	0.263
T92 Sequelae of injuries of upper limb	0.736	0.264
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.736	0.264
G59 Mononeuropathy in diseases classified elsewhere	0.735	0.265
G57 Mononeuropathies of lower limb	0.734	0.266
L30 Other dermatitis	0.734	0.266
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.733	0.267
I22.1 Subsequent myocardial infarction of inferior wall	0.732	0.267
E70-E90 Metabolic disorders	0.732	0.268
T15-T19 Effects of foreign body entering through natural orifice	0.731	0.269
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.731	0.269
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.731	0.269
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.731	0.269
M50.3 Other cervical disk degeneration	0.729	0.271
J47 Bronchiectasis	0.728	0.272
S05 Injury of eye and orbit	0.728	0.272
M25.55 Pain in joint (Pelvic region and thigh)	0.728	0.272
R25.2 Cramp and spasm	0.728	0.272
R79.8 Other specified abnormal findings of blood chemistry	0.727	0.273
M86-M90 Other osteopathies	0.724	0.275
G55.2 Nerve root and plexus compressions in spondylosis	0.725	0.275
M65.3 Trigger finger	0.724	0.276
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.724	0.276
J44 Other chronic obstructive pulmonary disease	0.724	0.276
R72 Abnormality of white blood cells, not elsewhere classified	0.722	0.278
L43 Lichen planus	0.722	0.278
J13 Pneumonia due to Streptococcus pneumoniae	0.722	0.278
J60-J70 Lung diseases due to external agents	0.722	0.278
Q38-Q45 Other congenital malformations of the digestive system	0.722	0.278
I95-I99 Other and unspecified disorders of the circulatory system	0.721	0.279
M22 Disorders of patella	0.720	0.280
M05 Seropositive rheumatoid arthritis	0.720	0.280
H10-H13 Disorders of conjunctiva	0.719	0.281
M40-M43 Deforming dorsopathies	0.719	0.281
J81 Pulmonary oedema	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.715	0.285
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.715	0.285
M34 Systemic sclerosis	0.715	0.285
M33 Dermatopolymyositis	0.715	0.285
M32 Systemic lupus erythematosus	0.715	0.285
M30 Polyarteritis nodosa and related conditions	0.715	0.285
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.715	0.285
J37 Chronic laryngitis and laryngotracheitis	0.714	0.286
J33.8 Other polyp of sinus	0.714	0.286
L40 Psoriasis	0.713	0.287
M13.94 Arthritis, unspecified (Hand)	0.713	0.287
M23.5 Chronic instability of knee	0.713	0.287
H30-H36 Disorders of choroid and retina	0.712	0.288
R20.8 Other and unspecified disturbances of skin sensation	0.711	0.289
J33.0 Polyp of nasal cavity	0.711	0.289
L00-L08 Infections of the skin and subcutaneous tissue	0.711	0.289
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.709	0.291
G51 Facial nerve disorders	0.709	0.291
M14 Arthropathies in other diseases classified elsewhere	0.709	0.291
M12 Other specific arthropathies	0.709	0.291
M09 Juvenile arthritis in diseases classified elsewhere	0.709	0.291
M08 Juvenile arthritis	0.709	0.291
M54.9 Dorsalgia, unspecified	0.709	0.291
J34.3 Hypertrophy of nasal turbinates	0.709	0.291
T93 Sequelae of injuries of lower limb	0.709	0.291
S90-S99 Injuries to the ankle and foot	0.708	0.292
R59.9 Enlarged lymph nodes, unspecified	0.708	0.292
R63.8 Other symptoms and signs concerning food and fluid intake	0.708	0.292
B99-B99 Other infectious diseases	0.707	0.293
B90-B94 Sequelae of infectious and parasitic diseases	0.707	0.293
B85-B89 Pediculosis, acariasis and other infestations	0.707	0.293
B65-B83 Helminthiases	0.707	0.293
B50-B64 Protozoal diseases	0.707	0.293
B20-B24 Human immunodeficiency virus [HIV] disease	0.707	0.293
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.707	0.293
A80-A89 Viral infections of the central nervous system	0.707	0.293
A75-A79 Rickettsioses	0.707	0.293
A70-A74 Other diseases caused by chlamydiae	0.707	0.293
A65-A69 Other spirochaetal diseases	0.707	0.293
A50-A64 Infections with a predominantly sexual mode of transmission	0.707	0.293
A20-A28 Certain zoonotic bacterial diseases	0.707	0.293
A15-A19 Tuberculosis	0.707	0.293
Q60-Q64 Congenital malformations of the urinary system	0.705	0.294
M76 Enthesopathies of lower limb, excluding foot	0.705	0.295
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.704	0.296
G00-G09 Inflammatory diseases of the central nervous system	0.704	0.296
T33-T35 Frostbite	0.704	0.296
T26-T28 Burns and corrosions confined to eye and internal organs	0.704	0.296
T20-T25 Burns and corrosions of external body surface, specified by site	0.704	0.296
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.704	0.296
T00-T07 Injuries involving multiple body regions	0.704	0.296
M75 Shoulder lesions	0.704	0.296
R92 Abnormal findings on diagnostic imaging of breast	0.703	0.297
J98.4 Other disorders of lung	0.703	0.297
R76.8 Other specified abnormal immunological findings in serum	0.702	0.298
R74 Abnormal serum enzyme levels	0.702	0.298
T79-T79 Certain early complications of trauma	0.701	0.299
R61 Hyperhidrosis	0.701	0.299
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.701	0.299
B15-B19 Viral hepatitis	0.698	0.302
M25.54 Pain in joint (Hand)	0.697	0.303
M11 Other crystal arthropathies	0.696	0.303
E04 Other non-toxic goitre	0.696	0.304
R90 Abnormal findings on diagnostic imaging of central nervous system	0.696	0.304
S80-S89 Injuries to the knee and lower leg	0.696	0.304
J98.8 Other specified respiratory disorders	0.696	0.304
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.696	0.304
M31.6 Other giant cell arteritis	0.693	0.307
I15 Secondary hypertension	0.693	0.307
I13 Hypertensive heart and renal disease	0.693	0.307
I11 Hypertensive heart disease	0.693	0.307
M20.2 Hallux rigidus	0.692	0.308
I64 Stroke, not specified as haemorrhage or infarction	0.692	0.308
Q20-Q28 Congenital malformations of the circulatory system	0.691	0.309
M23.9 Internal derangement of knee, unspecified	0.691	0.309
M23.4 Loose body in knee	0.691	0.309
M23.1 Discoid meniscus (congenital)	0.691	0.309
M23.0 Cystic meniscus	0.691	0.309
J31.2 Chronic pharyngitis	0.690	0.310
J31.1 Chronic nasopharyngitis	0.690	0.310
M53 Other dorsopathies, not elsewhere classified	0.688	0.312
G54 Nerve root and plexus disorders	0.688	0.312
G53 Cranial nerve disorders in diseases classified elsewhere	0.688	0.312
G52 Disorders of other cranial nerves	0.688	0.312
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.688	0.312
L50-L54 Urticaria and erythema	0.687	0.313
M84 Disorders of continuity of bone	0.686	0.314
R42 Dizziness and giddiness	0.684	0.316
J17 Pneumonia in diseases classified elsewhere	0.682	0.318
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.682	0.318
J15 Bacterial pneumonia, not elsewhere classified	0.682	0.318
J12 Viral pneumonia, not elsewhere classified	0.682	0.318
J11 Influenza, virus not identified	0.682	0.318
J10 Influenza due to identified influenza virus	0.682	0.318
J14 Pneumonia due to Haemophilus influenzae	0.682	0.318
J09 Influenza due to certain identified influenza virus	0.682	0.318
R26 Abnormalities of gait and mobility	0.682	0.318
S60-S69 Injuries to the wrist and hand	0.682	0.318
J99 Respiratory disorders in diseases classified elsewhere	0.680	0.320
R60 Oedema, not elsewhere classified	0.680	0.320
M85 Other disorders of bone density and structure	0.680	0.320
J98.0 Diseases of bronchus, not elsewhere classified	0.679	0.321
L27 Dermatitis due to substances taken internally	0.679	0.321
R80 Isolated proteinuria	0.678	0.322
J32 Chronic sinusitis	0.677	0.323
A00-A09 Intestinal infectious diseases	0.677	0.323
B44 Aspergillosis	0.677	0.323
R41 Other symptoms and signs involving cognitive functions and awareness	0.677	0.323
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.675	0.325
R62 Lack of expected normal physiological development	0.675	0.325
R64 Cachexia	0.675	0.325
R58 Haemorrhage, not elsewhere classified	0.675	0.325
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.675	0.325
I08.1 Disorders of both mitral and tricuspid valves	0.675	0.325
S02.6 Fracture of mandible	0.673	0.326
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.673	0.327
J42 Unspecified chronic bronchitis	0.672	0.328
B37.8 Candidiasis of other sites	0.672	0.328
I22.0 Subsequent myocardial infarction of anterior wall	0.672	0.328
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.671	0.329
S08 Traumatic amputation of part of head	0.671	0.329
S07 Crushing injury of head	0.671	0.329
S04 Injury of cranial nerves	0.671	0.329
S03 Dislocation, sprain and strain of joints and ligaments of head	0.671	0.329
Chapter V Mental and behavioural disorders	0.671	0.329
I21.X Presumed acute myicardial infaction (unconfirmed)	0.670	0.330
I21.3 Acute transmural myocardial infarction of unspecified site	0.670	0.330
S06.5 Traumatic subdural haemorrhage	0.670	0.330
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.670	0.330
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.669	0.331
R78 Findings of drugs and other substances, not normally found in blood	0.669	0.331
R77 Other abnormalities of plasma proteins	0.669	0.331
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.669	0.331
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.669	0.331
R71 Abnormality of red blood cells	0.669	0.331
J35.0 Chronic tonsillitis	0.669	0.331
B97 Viral agents as the cause of diseases classified to other chapters	0.669	0.331
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.668	0.332
M66 Spontaneous rupture of synovium and tendon	0.668	0.332
M25.8 Other specified joint disorders	0.668	0.332
L60-L75 Disorders of skin appendages	0.668	0.332
Q50-Q56 Congenital malformations of genital organs	0.668	0.332
R56 Convulsions, not elsewhere classified	0.668	0.332
S00.9 Superficial injury of head, part unspecified	0.667	0.333
H46-H48 Disorders of optic nerve and visual pathways	0.667	0.333
S09.9 Unspecified injury of head	0.665	0.334
I25.5 Ischaemic cardiomyopathy	0.665	0.335
L30.9 Dermatitis, unspecified	0.665	0.335
J30.4 Allergic rhinitis, unspecified	0.665	0.335
I20.1 Angina pectoris with documented spasm	0.665	0.335
M81.9 Osteoporosis, unspecified	0.664	0.336
R27 Other lack of coordination	0.664	0.336
L10-L14 Bullous disorders	0.663	0.337
G80-G83 Cerebral palsy and other paralytic syndromes	0.663	0.337
E87 Other disorders of fluid, electrolyte and acid-base balance	0.662	0.338
G95 Other diseases of spinal cord	0.661	0.339
M54.4 Lumbago with sciatica	0.661	0.339
M06.8 Other specified rheumatoid arthritis	0.659	0.341
M06.4 Inflammatory polyarthropathy	0.659	0.341
M06.3 Rheumatoid nodule	0.659	0.341
M06.2 Rheumatoid bursitis	0.659	0.341
M06.1 Adult-onset Still's disease	0.659	0.341
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.658	0.342
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.658	0.342
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.658	0.342
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.657	0.343
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.657	0.343
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.656	0.343
E40-E46 Malnutrition	0.656	0.344
M13.8 Other specified arthritis	0.656	0.344
M13.1 Monoarthritis, not elsewhere classified	0.656	0.344
R25.8 Other and unspecified abnormal involuntary movements	0.655	0.344
I21.4 Acute subendocardial myocardial infarction	0.655	0.345
G56.9 Mononeuropathy of upper limb, unspecified	0.655	0.345
G56.8 Other mononeuropathies of upper limb	0.655	0.345
G56.4 Causalgia	0.655	0.345
G56.3 Lesion of radial nerve	0.655	0.345
G56.1 Other lesions of median nerve	0.655	0.345
H55 Nystagmus and other irregular eye movements	0.655	0.345
J44.9 Chronic obstructive pulmonary disease, unspecified	0.655	0.345
T90 Sequelae of injuries of head	0.654	0.346
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.654	0.346
I25.8 Other forms of chronic ischaemic heart disease	0.653	0.347
J18.8 Other pneumonia, organism unspecified	0.653	0.347
J18.2 Hypostatic pneumonia, unspecified	0.653	0.347
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.653	0.347
M13.98 Arthritis, unspecified (Other)	0.652	0.348
M25.9 Joint disorder, unspecified	0.651	0.349
M25.6 Stiffness of joint, not elsewhere classified	0.651	0.349
M25.3 Other instability of joint	0.651	0.349
M25.2 Flail joint	0.651	0.349
M25.1 Fistula of joint	0.651	0.349
M25.0 Haemarthrosis	0.651	0.349
I62 Other nontraumatic intracranial haemorrhage	0.651	0.349
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.651	0.349
G30-G32 Other degenerative diseases of the nervous system	0.651	0.349
A30-A49 Other bacterial diseases	0.650	0.349
B33 Other viral diseases, not elsewhere classified	0.650	0.350
B30 Viral conjunctivitis	0.650	0.350
B27 Infectious mononucleosis	0.650	0.350
B26 Mumps	0.650	0.350
B25 Cytomegaloviral disease	0.650	0.350
R57.0 Cardiogenic shock	0.650	0.350
M10.96 Gout, unspecified (Lower leg)	0.649	0.351
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.649	0.351
J35.1 Hypertrophy of tonsils	0.648	0.352
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.647	0.353
J30.1 Allergic rhinitis due to pollen	0.646	0.354
E04.9 Non-toxic goitre, unspecified	0.646	0.354
T51.0 Ethanol	0.646	0.354
G96 Other disorders of central nervous system	0.645	0.354
B37.9 Candidiasis, unspecified	0.645	0.355
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.645	0.355
J96 Respiratory failure, not elsewhere classified	0.644	0.355
G43 Migraine	0.644	0.356
M25.4 Effusion of joint	0.644	0.356
M77 Other enthesopathies	0.643	0.357
H65-H75 Diseases of middle ear and mastoid	0.643	0.357
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.642	0.357
J35.8 Other chronic diseases of tonsils and adenoids	0.642	0.358
B37.3 Candidiasis of vulva and vagina	0.640	0.360
R44 Other symptoms and signs involving general sensations and perceptions	0.640	0.360
M65.8 Other synovitis and tenosynovitis	0.639	0.361
M65.4 Radial styloid tenosynovitis [de Quervain]	0.639	0.361
M65.2 Calcific tendinitis	0.639	0.361
M65.1 Other infective (teno)synovitis	0.639	0.361
M65.0 Abscess of tendon sheath	0.639	0.361
M79.8 Other specified soft tissue disorders	0.639	0.361
L43.9 Lichen planus, unspecified	0.638	0.362
M73 Soft tissue disorders in diseases classified elsewhere	0.636	0.363
M71 Other bursopathies	0.636	0.363
R12 Heartburn	0.636	0.364
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.636	0.364
Q80-Q89 Other congenital malformations	0.636	0.364
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.636	0.364
Q35-Q37 Cleft lip and cleft palate	0.636	0.364
Q30-Q34 Congenital malformations of the respiratory system	0.636	0.364
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.636	0.364
Q00-Q07 Congenital malformations of the nervous system	0.636	0.364
J39 Other diseases of upper respiratory tract	0.636	0.364
B48 Other mycoses, not elsewhere classified	0.635	0.365
B47 Mycetoma	0.635	0.365
B46 Zygomycosis	0.635	0.365
B45 Cryptococcosis	0.635	0.365
B43 Chromomycosis and phaeomycotic abscess	0.635	0.365
B42 Sporotrichosis	0.635	0.365
B41 Paracoccidioidomycosis	0.635	0.365
B40 Blastomycosis	0.635	0.365
B39 Histoplasmosis	0.635	0.365
B38 Coccidioidomycosis	0.635	0.365
B36 Other superficial mycoses	0.635	0.365
B35 Dermatophytosis	0.635	0.365
B49 Unspecified mycosis	0.635	0.365
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.635	0.365
G50 Disorders of trigeminal nerve	0.635	0.365
G70 Myasthenia gravis and other myoneural disorders	0.634	0.365
R63.6 Insufficient intake of food and water due to self neglect	0.634	0.366
R63.5 Abnormal weight gain	0.634	0.366
R63.3 Feeding difficulties and mismanagement	0.634	0.366
R63.2 Polyphagia	0.634	0.366
R63.1 Polydipsia	0.634	0.366
M83 Adult osteomalacia	0.634	0.366
M82 Osteoporosis in diseases classified elsewhere	0.634	0.366
R82 Other abnormal findings in urine	0.633	0.367
M51.8 Other specified intervertebral disk disorders	0.633	0.367
J18.0 Bronchopneumonia, unspecified	0.632	0.368
J38.1 Polyp of vocal cord and larynx	0.631	0.369
G58.9 Mononeuropathy, unspecified	0.631	0.369
M80 Osteoporosis with pathological fracture	0.631	0.369
M70 Soft tissue disorders related to use, overuse and pressure	0.630	0.370
M54.2 Cervicalgia	0.630	0.370
H57 Other disorders of eye and adnexa	0.630	0.370
I28 Other diseases of pulmonary vessels	0.629	0.370
R79.0 Abnormal level of blood mineral	0.629	0.371
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.628	0.372
M50.1 Cervical disk disorder with radiculopathy	0.627	0.372
R14 Flatulence and related conditions	0.627	0.373
T92.1 Sequelae of fracture of arm	0.627	0.373
J46 Status asthmaticus	0.627	0.373
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.627	0.373
I07 Rheumatic tricuspid valve diseases	0.626	0.374
T98 Sequelae of other and unspecified effects of external causes	0.625	0.375
T95 Sequelae of burns, corrosions and frostbite	0.625	0.375
T94 Sequelae of injuries involving multiple and unspecified body regions	0.625	0.375
T91 Sequelae of injuries of neck and trunk	0.625	0.375
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.625	0.375
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.625	0.375
R25.3 Fasciculation	0.624	0.375
R25.0 Abnormal head movements	0.624	0.375
M79.0 Rheumatism, unspecified	0.624	0.376
I08.2 Disorders of both aortic and tricuspid valves	0.623	0.377
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.623	0.377
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.623	0.377
M46 Other inflammatory spondylopathies	0.623	0.377
Chapter XV Pregnancy, childbirth and the puerperium	0.623	0.377
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.622	0.377
E05 Thyrotoxicosis [hyperthyroidism]	0.622	0.378
R23 Other skin changes	0.622	0.378

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations