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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115717162
log Bayes Factor = 14.5807
Chromosome 5   position 40,088,101  (GRCh37) Explore rs115717162 on Ensembl!
Variant rs115717162 is part of Cluster X0143

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
M20-M25 Other joint disorders
0.997 0.003 0.000
J30-J39 Other diseases of upper respiratory tract
0.996 0.004 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
Chapter I Certain infectious and parasitic diseases
0.986 0.014 0.000
Chapter VI Diseases of the nervous system
0.982 0.018 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.982 0.018 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.981 0.019 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.967 0.033 0.000
I10-I15 Hypertensive diseases
0.966 0.034 0.000
M23 Internal derangement of knee
0.963 0.037 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.962 0.038 0.000
M50-M54 Other dorsopathies
0.960 0.040 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.960 0.040 0.000
J09-J18 Influenza and pneumonia
0.951 0.049 0.000
I10 Essential (primary) hypertension
0.949 0.051 0.000
R50-R69 General symptoms and signs
0.942 0.058 0.000
B95-B98 Bacterial, viral and other infectious agents
0.939 0.061 0.000
J31.0 Chronic rhinitis
0.938 0.062 0.000
I22 Subsequent myocardial infarction
0.937 0.063 0.000
S00-S09 Injuries to the head
0.936 0.064 0.000
I21 Acute myocardial infarction
0.935 0.065 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.933 0.067 0.000
M65-M68 Disorders of synovium and tendon
0.932 0.068 0.000
I20 Angina pectoris
0.927 0.073 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.926 0.074 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.924 0.076 0.000
M06 Other rheumatoid arthritis
0.919 0.081 0.000
R47-R49 Symptoms and signs involving speech and voice
0.918 0.082 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.916 0.084 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.916 0.084 0.000
M13 Other arthritis
0.915 0.085 0.000
G56 Mononeuropathies of upper limb
0.914 0.086 0.000
J18 Pneumonia, organism unspecified
0.911 0.089 0.000
M25 Other joint disorders, not elsewhere classified
0.909 0.091 0.000
B25-B34 Other viral diseases
0.907 0.093 0.000
J95-J99 Other diseases of the respiratory system
0.899 0.101 0.000
J36 Peritonsillar abscess
0.896 0.104 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.893 0.107 0.000
M65 Synovitis and tenosynovitis
0.892 0.108 0.000
M70-M79 Other soft tissue disorders
0.888 0.112 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.887 0.113 0.000
R59 Enlarged lymph nodes
0.886 0.114 0.000
B35-B49 Mycoses
0.886 0.114 0.000
G56.0 Carpal tunnel syndrome
0.885 0.115 0.000
R63 Symptoms and signs concerning food and fluid intake
0.885 0.115 0.000
M80-M85 Disorders of bone density and structure
0.884 0.116 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.878 0.122 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.872 0.128 0.000
R25 Abnormal involuntary movements
0.871 0.129 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.864 0.136 0.000
I25 Chronic ischaemic heart disease
0.864 0.136 0.000
M50 Cervical disk disorders
0.864 0.136 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.864 0.136 0.000
R53 Malaise and fatigue
0.859 0.141 0.000
M10 Gout
0.859 0.141 0.000
I05-I09 Chronic rheumatic heart diseases
0.858 0.142 0.000
R63.4 Abnormal weight loss
0.857 0.143 0.000
J40-J47 Chronic lower respiratory diseases
0.854 0.146 0.000
Chapter VII Diseases of the eye and adnexa
0.853 0.147 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.852 0.148 0.000
B34 Viral infection of unspecified site
0.851 0.149 0.000
J18.9 Pneumonia, unspecified
0.849 0.151 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.849 0.151 0.000
M20 Acquired deformities of fingers and toes
0.846 0.154 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.845 0.155 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.843 0.157 0.000
M06.9 Rheumatoid arthritis, unspecified
0.841 0.159 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.840 0.160 0.000
J35 Chronic diseases of tonsils and adenoids
0.838 0.162 0.000
L40-L45 Papulosquamous disorders
0.838 0.162 0.000
I20.8 Other forms of angina pectoris
0.838 0.162 0.000
M13.9 Arthritis, unspecified
0.838 0.162 0.000
M23.8 Other internal derangements of knee
0.833 0.167 0.000
M54 Dorsalgia
0.830 0.170 0.000
I20.9 Angina pectoris, unspecified
0.830 0.170 0.000
L20-L30 Dermatitis and eczema
0.829 0.171 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.827 0.173 0.000
J98 Other respiratory disorders
0.827 0.173 0.000
J30 Vasomotor and allergic rhinitis
0.825 0.175 0.000
R49 Voice disturbances
0.824 0.176 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.823 0.177 0.000
R79 Other abnormal findings of blood chemistry
0.823 0.177 0.000
M20.1 Hallux valgus (acquired)
0.821 0.179 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.820 0.180 0.000
M31 Other necrotising vasculopathies
0.820 0.180 0.000
I21.9 Acute myocardial infarction, unspecified
0.820 0.180 0.000
J33 Nasal polyp
0.819 0.181 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.818 0.182 0.000
G90-G99 Other disorders of the nervous system
0.816 0.184 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.813 0.187 0.000
S10-S19 Injuries to the neck
0.810 0.189 0.000
B34.9 Viral infection, unspecified
0.810 0.190 0.000
R13 Dysphagia
0.808 0.192 0.000
M25.5 Pain in joint
0.805 0.195 0.000
I25.1 Atherosclerotic heart disease
0.805 0.195 0.000
B37 Candidiasis
0.800 0.200 0.000
G70-G73 Diseases of myoneural junction and muscle
0.800 0.200 0.000
J18.1 Lobar pneumonia, unspecified
0.799 0.201 0.000
R76 Other abnormal immunological findings in serum
0.798 0.202 0.000
S02 Fracture of skull and facial bones
0.798 0.202 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.796 0.204 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.795 0.204 0.000
I26 Pulmonary embolism
0.795 0.205 0.000
R25.1 Tremor, unspecified
0.794 0.206 0.000
M45-M49 Spondylopathies
0.794 0.206 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.792 0.208 0.000
M51 Other intervertebral disk disorders
0.791 0.209 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.791 0.209 0.000
I60-I69 Cerebrovascular diseases
0.789 0.211 0.000
R57 Shock, not elsewhere classified
0.788 0.212 0.000
R59.1 Generalised enlarged lymph nodes
0.787 0.213 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.786 0.214 0.000
S06 Intracranial injury
0.785 0.215 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.783 0.217 0.000
Chapter VIII Diseases of the ear and mastoid process
0.783 0.217 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.781 0.219 0.000
J34 Other disorders of nose and nasal sinuses
0.780 0.220 0.000
I22.8 Subsequent myocardial infarction of other sites
0.779 0.221 0.000
S09 Other and unspecified injuries of head
0.778 0.222 0.000
R17 Unspecified jaundice
0.777 0.223 0.000
S00 Superficial injury of head
0.776 0.224 0.000
E00-E07 Disorders of thyroid gland
0.772 0.228 0.000
M24 Other specific joint derangements
0.771 0.229 0.000
R54 Senility
0.770 0.230 0.000
S40-S49 Injuries to the shoulder and upper arm
0.770 0.230 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.769 0.231 0.000
G58 Other mononeuropathies
0.768 0.232 0.000
I24 Other acute ischaemic heart diseases
0.768 0.232 0.000
M21 Other acquired deformities of limbs
0.767 0.233 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.767 0.233 0.000
M10.9 Gout, unspecified
0.766 0.234 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.763 0.237 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.762 0.238 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.762 0.238 0.000
H55-H59 Other disorders of eye and adnexa
0.762 0.238 0.000
M50.0 Cervical disk disorder with myelopathy
0.759 0.241 0.000
R49.0 Dysphonia
0.757 0.243 0.000
M81 Osteoporosis without pathological fracture
0.756 0.244 0.000
S70-S79 Injuries to the hip and thigh
0.755 0.245 0.000
M35 Other systemic involvement of connective tissue
0.755 0.245 0.000
R47 Speech disturbances, not elsewhere classified
0.754 0.246 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.754 0.246 0.000
I08 Multiple valve diseases
0.752 0.248 0.000
M06.0 Seronegative rheumatoid arthritis
0.751 0.249 0.000
T51 Toxic effect of alcohol
0.747 0.253 0.000
R59.0 Localised enlarged lymph nodes
0.745 0.255 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.745 0.255 0.000
R20 Disturbances of skin sensation
0.744 0.256 0.000
M25.7 Osteophyte
0.744 0.256 0.000
S20-S29 Injuries to the thorax
0.742 0.257 0.000
G40-G47 Episodic and paroxysmal disorders
0.740 0.260 0.000
M91-M94 Chondropathies
0.739 0.261 0.000
Chapter XX External causes of morbidity and mortality
0.739 0.261 0.000
M07 Psoriatic and enteropathic arthropathies
0.738 0.262 0.000
R68 Other general symptoms and signs
0.737 0.263 0.000
M13.0 Polyarthritis, unspecified
0.737 0.263 0.000
T92 Sequelae of injuries of upper limb
0.736 0.264 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.736 0.264 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.735 0.265 0.000
G57 Mononeuropathies of lower limb
0.734 0.266 0.000
L30 Other dermatitis
0.734 0.266 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.733 0.267 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.732 0.267 0.000
E70-E90 Metabolic disorders
0.732 0.268 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.731 0.269 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.731 0.269 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.731 0.269 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.731 0.269 0.000
M50.3 Other cervical disk degeneration
0.729 0.271 0.000
J47 Bronchiectasis
0.728 0.272 0.000
S05 Injury of eye and orbit
0.728 0.272 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.728 0.272 0.000
R25.2 Cramp and spasm
0.728 0.272 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.727 0.273 0.000
M86-M90 Other osteopathies
0.724 0.275 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.725 0.275 0.000
M65.3 Trigger finger
0.724 0.276 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.724 0.276 0.000
J44 Other chronic obstructive pulmonary disease
0.724 0.276 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.722 0.278 0.000
L43 Lichen planus
0.722 0.278 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.722 0.278 0.000
J60-J70 Lung diseases due to external agents
0.722 0.278 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.722 0.278 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.721 0.279 0.000
M22 Disorders of patella
0.720 0.280 0.000
M05 Seropositive rheumatoid arthritis
0.720 0.280 0.000
H10-H13 Disorders of conjunctiva
0.719 0.281 0.000
M40-M43 Deforming dorsopathies
0.719 0.281 0.000
J81 Pulmonary oedema
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M34 Systemic sclerosis
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.715 0.285 0.000
J37 Chronic laryngitis and laryngotracheitis
0.714 0.286 0.000
J33.8 Other polyp of sinus
0.714 0.286 0.000
L40 Psoriasis
0.713 0.287 0.000
M13.94 Arthritis, unspecified (Hand)
0.713 0.287 0.000
M23.5 Chronic instability of knee
0.713 0.287 0.000
H30-H36 Disorders of choroid and retina
0.712 0.288 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.711 0.289 0.000
J33.0 Polyp of nasal cavity
0.711 0.289 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.711 0.289 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.709 0.291 0.000
G51 Facial nerve disorders
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M12 Other specific arthropathies
0.709 0.291 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
M54.9 Dorsalgia, unspecified
0.709 0.291 0.000
J34.3 Hypertrophy of nasal turbinates
0.709 0.291 0.000
T93 Sequelae of injuries of lower limb
0.709 0.291 0.000
S90-S99 Injuries to the ankle and foot
0.708 0.292 0.000
R59.9 Enlarged lymph nodes, unspecified
0.708 0.292 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.708 0.292 0.000
B99-B99 Other infectious diseases
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.293 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A80-A89 Viral infections of the central nervous system
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
Q60-Q64 Congenital malformations of the urinary system
0.705 0.294 0.000
M76 Enthesopathies of lower limb, excluding foot
0.705 0.295 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.704 0.296 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.704 0.296 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.704 0.296 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.704 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.296 0.000
M75 Shoulder lesions
0.704 0.296 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.703 0.297 0.000
J98.4 Other disorders of lung
0.703 0.297 0.000
R76.8 Other specified abnormal immunological findings in serum
0.702 0.298 0.000
R74 Abnormal serum enzyme levels
0.702 0.298 0.000
T79-T79 Certain early complications of trauma
0.701 0.299 0.000
R61 Hyperhidrosis
0.701 0.299 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.701 0.299 0.000
B15-B19 Viral hepatitis
0.698 0.302 0.000
M25.54 Pain in joint (Hand)
0.697 0.303 0.000
M11 Other crystal arthropathies
0.696 0.303 0.000
E04 Other non-toxic goitre
0.696 0.304 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.696 0.304 0.000
S80-S89 Injuries to the knee and lower leg
0.696 0.304 0.000
J98.8 Other specified respiratory disorders
0.696 0.304 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.696 0.304 0.000
M31.6 Other giant cell arteritis
0.693 0.307 0.000
I15 Secondary hypertension
0.693 0.307 0.000
I13 Hypertensive heart and renal disease
0.693 0.307 0.000
I11 Hypertensive heart disease
0.693 0.307 0.000
M20.2 Hallux rigidus
0.692 0.308 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.692 0.308 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.691 0.309 0.000
M23.9 Internal derangement of knee, unspecified
0.691 0.309 0.000
M23.4 Loose body in knee
0.691 0.309 0.000
M23.1 Discoid meniscus (congenital)
0.691 0.309 0.000
M23.0 Cystic meniscus
0.691 0.309 0.000
J31.2 Chronic pharyngitis
0.690 0.310 0.000
J31.1 Chronic nasopharyngitis
0.690 0.310 0.000
M53 Other dorsopathies, not elsewhere classified
0.688 0.312 0.000
G54 Nerve root and plexus disorders
0.688 0.312 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.688 0.312 0.000
G52 Disorders of other cranial nerves
0.688 0.312 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.688 0.312 0.000
L50-L54 Urticaria and erythema
0.687 0.313 0.000
M84 Disorders of continuity of bone
0.686 0.314 0.000
R42 Dizziness and giddiness
0.684 0.316 0.000
J17 Pneumonia in diseases classified elsewhere
0.682 0.318 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.682 0.318 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.682 0.318 0.000
J12 Viral pneumonia, not elsewhere classified
0.682 0.318 0.000
J11 Influenza, virus not identified
0.682 0.318 0.000
J10 Influenza due to identified influenza virus
0.682 0.318 0.000
J14 Pneumonia due to Haemophilus influenzae
0.682 0.318 0.000
J09 Influenza due to certain identified influenza virus
0.682 0.318 0.000
R26 Abnormalities of gait and mobility
0.682 0.318 0.000
S60-S69 Injuries to the wrist and hand
0.682 0.318 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.680 0.320 0.000
R60 Oedema, not elsewhere classified
0.680 0.320 0.000
M85 Other disorders of bone density and structure
0.680 0.320 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.679 0.321 0.000
L27 Dermatitis due to substances taken internally
0.679 0.321 0.000
R80 Isolated proteinuria
0.678 0.322 0.000
J32 Chronic sinusitis
0.677 0.323 0.000
A00-A09 Intestinal infectious diseases
0.677 0.323 0.000
B44 Aspergillosis
0.677 0.323 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.677 0.323 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.675 0.325 0.000
R62 Lack of expected normal physiological development
0.675 0.325 0.000
R64 Cachexia
0.675 0.325 0.000
R58 Haemorrhage, not elsewhere classified
0.675 0.325 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.675 0.325 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.675 0.325 0.000
S02.6 Fracture of mandible
0.673 0.326 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.673 0.327 0.000
J42 Unspecified chronic bronchitis
0.672 0.328 0.000
B37.8 Candidiasis of other sites
0.672 0.328 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.672 0.328 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.671 0.329 0.000
S08 Traumatic amputation of part of head
0.671 0.329 0.000
S07 Crushing injury of head
0.671 0.329 0.000
S04 Injury of cranial nerves
0.671 0.329 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.671 0.329 0.000
Chapter V Mental and behavioural disorders
0.671 0.329 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.670 0.330 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.670 0.330 0.000
S06.5 Traumatic subdural haemorrhage
0.670 0.330 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.670 0.330 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.669 0.331 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.669 0.331 0.000
R77 Other abnormalities of plasma proteins
0.669 0.331 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.669 0.331 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.669 0.331 0.000
R71 Abnormality of red blood cells
0.669 0.331 0.000
J35.0 Chronic tonsillitis
0.669 0.331 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.669 0.331 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.668 0.332 0.000
M66 Spontaneous rupture of synovium and tendon
0.668 0.332 0.000
M25.8 Other specified joint disorders
0.668 0.332 0.000
L60-L75 Disorders of skin appendages
0.668 0.332 0.000
Q50-Q56 Congenital malformations of genital organs
0.668 0.332 0.000
R56 Convulsions, not elsewhere classified
0.668 0.332 0.000
S00.9 Superficial injury of head, part unspecified
0.667 0.333 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.667 0.333 0.000
S09.9 Unspecified injury of head
0.665 0.334 0.000
I25.5 Ischaemic cardiomyopathy
0.665 0.335 0.000
L30.9 Dermatitis, unspecified
0.665 0.335 0.000
J30.4 Allergic rhinitis, unspecified
0.665 0.335 0.000
I20.1 Angina pectoris with documented spasm
0.665 0.335 0.000
M81.9 Osteoporosis, unspecified
0.664 0.336 0.000
R27 Other lack of coordination
0.664 0.336 0.000
L10-L14 Bullous disorders
0.663 0.337 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.663 0.337 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.662 0.338 0.000
G95 Other diseases of spinal cord
0.661 0.339 0.000
M54.4 Lumbago with sciatica
0.661 0.339 0.000
M06.8 Other specified rheumatoid arthritis
0.659 0.341 0.000
M06.4 Inflammatory polyarthropathy
0.659 0.341 0.000
M06.3 Rheumatoid nodule
0.659 0.341 0.000
M06.2 Rheumatoid bursitis
0.659 0.341 0.000
M06.1 Adult-onset Still's disease
0.659 0.341 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.658 0.342 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.658 0.342 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.658 0.342 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.657 0.343 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.657 0.343 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.656 0.343 0.000
E40-E46 Malnutrition
0.656 0.344 0.000
M13.8 Other specified arthritis
0.656 0.344 0.000
M13.1 Monoarthritis, not elsewhere classified
0.656 0.344 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.655 0.344 0.000
I21.4 Acute subendocardial myocardial infarction
0.655 0.345 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.655 0.345 0.000
G56.8 Other mononeuropathies of upper limb
0.655 0.345 0.000
G56.4 Causalgia
0.655 0.345 0.000
G56.3 Lesion of radial nerve
0.655 0.345 0.000
G56.1 Other lesions of median nerve
0.655 0.345 0.000
H55 Nystagmus and other irregular eye movements
0.655 0.345 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.655 0.345 0.000
T90 Sequelae of injuries of head
0.654 0.346 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.654 0.346 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.653 0.347 0.000
J18.8 Other pneumonia, organism unspecified
0.653 0.347 0.000
J18.2 Hypostatic pneumonia, unspecified
0.653 0.347 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.653 0.347 0.000
M13.98 Arthritis, unspecified (Other)
0.652 0.348 0.000
M25.9 Joint disorder, unspecified
0.651 0.349 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.651 0.349 0.000
M25.3 Other instability of joint
0.651 0.349 0.000
M25.2 Flail joint
0.651 0.349 0.000
M25.1 Fistula of joint
0.651 0.349 0.000
M25.0 Haemarthrosis
0.651 0.349 0.000
I62 Other nontraumatic intracranial haemorrhage
0.651 0.349 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.651 0.349 0.000
G30-G32 Other degenerative diseases of the nervous system
0.651 0.349 0.000
A30-A49 Other bacterial diseases
0.650 0.349 0.000
B33 Other viral diseases, not elsewhere classified
0.650 0.350 0.000
B30 Viral conjunctivitis
0.650 0.350 0.000
B27 Infectious mononucleosis
0.650 0.350 0.000
B26 Mumps
0.650 0.350 0.000
B25 Cytomegaloviral disease
0.650 0.350 0.000
R57.0 Cardiogenic shock
0.650 0.350 0.000
M10.96 Gout, unspecified (Lower leg)
0.649 0.351 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.649 0.351 0.000
J35.1 Hypertrophy of tonsils
0.648 0.352 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.647 0.353 0.000
J30.1 Allergic rhinitis due to pollen
0.646 0.354 0.000
E04.9 Non-toxic goitre, unspecified
0.646 0.354 0.000
T51.0 Ethanol
0.646 0.354 0.000
G96 Other disorders of central nervous system
0.645 0.354 0.000
B37.9 Candidiasis, unspecified
0.645 0.355 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.645 0.355 0.000
J96 Respiratory failure, not elsewhere classified
0.644 0.355 0.000
G43 Migraine
0.644 0.356 0.000
M25.4 Effusion of joint
0.644 0.356 0.000
M77 Other enthesopathies
0.643 0.357 0.000
H65-H75 Diseases of middle ear and mastoid
0.643 0.357 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.642 0.357 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.642 0.358 0.000
B37.3 Candidiasis of vulva and vagina
0.640 0.360 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.640 0.360 0.000
M65.8 Other synovitis and tenosynovitis
0.639 0.361 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.639 0.361 0.000
M65.2 Calcific tendinitis
0.639 0.361 0.000
M65.1 Other infective (teno)synovitis
0.639 0.361 0.000
M65.0 Abscess of tendon sheath
0.639 0.361 0.000
M79.8 Other specified soft tissue disorders
0.639 0.361 0.000
L43.9 Lichen planus, unspecified
0.638 0.362 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.636 0.363 0.000
M71 Other bursopathies
0.636 0.363 0.000
R12 Heartburn
0.636 0.364 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.636 0.364 0.000
Q80-Q89 Other congenital malformations
0.636 0.364 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.636 0.364 0.000
Q35-Q37 Cleft lip and cleft palate
0.636 0.364 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.636 0.364 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.636 0.364 0.000
Q00-Q07 Congenital malformations of the nervous system
0.636 0.364 0.000
J39 Other diseases of upper respiratory tract
0.636 0.364 0.000
B48 Other mycoses, not elsewhere classified
0.635 0.365 0.000
B47 Mycetoma
0.635 0.365 0.000
B46 Zygomycosis
0.635 0.365 0.000
B45 Cryptococcosis
0.635 0.365 0.000
B43 Chromomycosis and phaeomycotic abscess
0.635 0.365 0.000
B42 Sporotrichosis
0.635 0.365 0.000
B41 Paracoccidioidomycosis
0.635 0.365 0.000
B40 Blastomycosis
0.635 0.365 0.000
B39 Histoplasmosis
0.635 0.365 0.000
B38 Coccidioidomycosis
0.635 0.365 0.000
B36 Other superficial mycoses
0.635 0.365 0.000
B35 Dermatophytosis
0.635 0.365 0.000
B49 Unspecified mycosis
0.635 0.365 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.635 0.365 0.000
G50 Disorders of trigeminal nerve
0.635 0.365 0.000
G70 Myasthenia gravis and other myoneural disorders
0.634 0.365 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.634 0.366 0.000
R63.5 Abnormal weight gain
0.634 0.366 0.000
R63.3 Feeding difficulties and mismanagement
0.634 0.366 0.000
R63.2 Polyphagia
0.634 0.366 0.000
R63.1 Polydipsia
0.634 0.366 0.000
M83 Adult osteomalacia
0.634 0.366 0.000
M82 Osteoporosis in diseases classified elsewhere
0.634 0.366 0.000
R82 Other abnormal findings in urine
0.633 0.367 0.000
M51.8 Other specified intervertebral disk disorders
0.633 0.367 0.000
J18.0 Bronchopneumonia, unspecified
0.632 0.368 0.000
J38.1 Polyp of vocal cord and larynx
0.631 0.369 0.000
G58.9 Mononeuropathy, unspecified
0.631 0.369 0.000
M80 Osteoporosis with pathological fracture
0.631 0.369 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.630 0.370 0.000
M54.2 Cervicalgia
0.630 0.370 0.000
H57 Other disorders of eye and adnexa
0.630 0.370 0.000
I28 Other diseases of pulmonary vessels
0.629 0.370 0.000
R79.0 Abnormal level of blood mineral
0.629 0.371 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.628 0.372 0.000
M50.1 Cervical disk disorder with radiculopathy
0.627 0.372 0.000
R14 Flatulence and related conditions
0.627 0.373 0.000
T92.1 Sequelae of fracture of arm
0.627 0.373 0.000
J46 Status asthmaticus
0.627 0.373 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.627 0.373 0.000
I07 Rheumatic tricuspid valve diseases
0.626 0.374 0.000
T98 Sequelae of other and unspecified effects of external causes
0.625 0.375 0.000
T95 Sequelae of burns, corrosions and frostbite
0.625 0.375 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.625 0.375 0.000
T91 Sequelae of injuries of neck and trunk
0.625 0.375 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.625 0.375 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.625 0.375 0.000
R25.3 Fasciculation
0.624 0.375 0.000
R25.0 Abnormal head movements
0.624 0.375 0.000
M79.0 Rheumatism, unspecified
0.624 0.376 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.623 0.377 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.623 0.377 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.623 0.377 0.000
M46 Other inflammatory spondylopathies
0.623 0.377 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.623 0.377 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.622 0.377 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.622 0.378 0.000
R23 Other skin changes
0.622 0.378 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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