TreeWAS – Variant ID: rs17797221

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
M45-M49 Spondylopathies	1.000	0.000
R50-R69 General symptoms and signs	0.999	0.001
M50-M54 Other dorsopathies	0.999	0.001
M06 Other rheumatoid arthritis	0.999	0.001
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001
T36-T50 Poisoning by drugs, medicaments and biological substances	0.998	0.002
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.998	0.002
Chapter IX Diseases of the circulatory system	0.997	0.003
M48 Other spondylopathies	0.996	0.004
R63 Symptoms and signs concerning food and fluid intake	0.995	0.005
M54 Dorsalgia	0.995	0.005
M06.9 Rheumatoid arthritis, unspecified	0.995	0.005
M48.0 Spinal stenosis	0.994	0.006
M20-M25 Other joint disorders	0.993	0.007
Chapter II Neoplasms	0.992	0.008
M48.06 Spinal stenosis (Lumbar region)	0.991	0.009
M54.5 Low back pain	0.988	0.012
R63.4 Abnormal weight loss	0.988	0.012
Chapter X Diseases of the respiratory system	0.986	0.014
M47 Spondylosis	0.985	0.015
Z40-Z54 Persons encountering health services for specific procedures and health care	0.982	0.018
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.981	0.019
Z90 Acquired absence of organs, not elsewhere classified	0.981	0.019
I20-I25 Ischaemic heart diseases	0.980	0.020
Z51 Other medical care	0.978	0.022
Z51.2 Other chemotherapy	0.976	0.024
J30-J39 Other diseases of upper respiratory tract	0.972	0.028
I25 Chronic ischaemic heart disease	0.972	0.028
M54.56 Low back pain (Lumbar region)	0.972	0.028
Chapter I Certain infectious and parasitic diseases	0.968	0.032
S60-S69 Injuries to the wrist and hand	0.968	0.032
Z80 Family history of malignant neoplasm	0.965	0.035
M47.9 Spondylosis, unspecified	0.963	0.037
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.963	0.037
M70-M79 Other soft tissue disorders	0.962	0.038
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.960	0.040
M13 Other arthritis	0.959	0.041
J34 Other disorders of nose and nasal sinuses	0.959	0.041
I25.9 Chronic ischaemic heart disease, unspecified	0.957	0.043
J34.8 Other specified disorders of nose and nasal sinuses	0.951	0.049
R52 Pain, not elsewhere classified	0.950	0.050
I70-I79 Diseases of arteries, arterioles and capillaries	0.949	0.051
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.947	0.053
M25 Other joint disorders, not elsewhere classified	0.945	0.055
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.943	0.057
M80-M85 Disorders of bone density and structure	0.942	0.058
M79 Other soft tissue disorders, not elsewhere classified	0.941	0.059
C43-C44 Melanoma and other malignant neoplasms of skin	0.936	0.064
M06.0 Seronegative rheumatoid arthritis	0.935	0.065
J00-J06 Acute upper respiratory infections	0.932	0.068
M20 Acquired deformities of fingers and toes	0.931	0.069
Z90.7 Acquired absence of genital organ(s)	0.930	0.070
R69 Unknown and unspecified causes of morbidity	0.929	0.071
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.927	0.073
R93 Abnormal findings on diagnostic imaging of other body structures	0.924	0.076
M79.6 Pain in limb	0.924	0.076
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.921	0.079
Z83 Family history of other specific disorders	0.920	0.080
M13.9 Arthritis, unspecified	0.919	0.081
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.913	0.087
I05-I09 Chronic rheumatic heart diseases	0.913	0.087
M54.59 Low back pain (Site unspecified)	0.909	0.091
C60-C63 Malignant neoplasms of male genital organs	0.907	0.093
Z90.4 Acquired absence of other parts of digestive tract	0.905	0.095
Z80.0 Family history of malignant neoplasm of digestive organs	0.902	0.098
M25.5 Pain in joint	0.901	0.099
Chapter XII Diseases of the skin and subcutaneous tissue	0.900	0.100
M50 Cervical disk disorders	0.897	0.103
T43.2 Other and unspecified antidepressants	0.896	0.104
R52.2 Other chronic pain	0.896	0.104
Z50 Care involving use of rehabilitation procedures	0.893	0.107
D50-D53 Nutritional anaemias	0.893	0.107
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.892	0.108
Z91 Personal history of risk-factors, not elsewhere classified	0.888	0.112
Chapter VI Diseases of the nervous system	0.883	0.117
Z92 Personal history of medical treatment	0.881	0.119
R63.0 Anorexia	0.880	0.120
Z93 Artificial opening status	0.880	0.120
D37-D48 Neoplasms of uncertain or unknown behaviour	0.880	0.120
M51 Other intervertebral disk disorders	0.878	0.122
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.878	0.122
D70-D77 Other diseases of blood and blood-forming organs	0.876	0.124
M15-M19 Arthrosis	0.873	0.127
J32 Chronic sinusitis	0.872	0.128
M47.92 Spondylosis, unspecified (Cervical region)	0.870	0.130
Z92.1 Personal history of long-term (current) use of anticoagulants	0.868	0.132
S62 Fracture at wrist and hand level	0.868	0.132
M47.99 Spondylosis, unspecified (Site unspecified)	0.866	0.134
M13.90 Arthritis, unspecified (Multiple sites)	0.859	0.141
A30-A49 Other bacterial diseases	0.859	0.141
D00-D09 In situ neoplasms	0.859	0.141
R51 Headache	0.859	0.141
Z80.4 Family history of malignant neoplasm of genital organs	0.859	0.141
R59 Enlarged lymph nodes	0.858	0.142
M54.9 Dorsalgia, unspecified	0.858	0.142
M25.56 Pain in joint (Lower leg)	0.857	0.143
M24 Other specific joint derangements	0.855	0.145
C44 Other malignant neoplasms of skin	0.854	0.146
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.853	0.147
Z94 Transplanted organ and tissue status	0.853	0.147
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.852	0.148
M05 Seropositive rheumatoid arthritis	0.851	0.148
Z97 Presence of other devices	0.851	0.149
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.851	0.149
M47.8 Other spondylosis	0.849	0.151
C61 Malignant neoplasm of prostate	0.849	0.151
S66 Injury of muscle and tendon at wrist and hand level	0.848	0.152
M79.66 Pain in limb (Lower leg)	0.847	0.153
I60-I69 Cerebrovascular diseases	0.846	0.154
Z91.5 Personal history of self-harm	0.845	0.155
A00-A09 Intestinal infectious diseases	0.845	0.155
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.845	0.155
J00 Acute nasopharyngitis [common cold]	0.842	0.158
Z30 Contraceptive management	0.840	0.160
I74 Arterial embolism and thrombosis	0.840	0.160
I25.2 Old myocardial infarction	0.840	0.160
M13.94 Arthritis, unspecified (Hand)	0.839	0.161
Z34 Supervision of normal pregnancy	0.838	0.162
R53 Malaise and fatigue	0.838	0.162
R61 Hyperhidrosis	0.838	0.162
C92 Myeloid leukaemia	0.833	0.167
T43.0 Tricyclic and tetracyclic antidepressants	0.833	0.167
Z90.5 Acquired absence of kidney	0.833	0.167
M20.2 Hallux rigidus	0.832	0.168
M45 Ankylosing spondylitis	0.827	0.173
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.826	0.174
I24 Other acute ischaemic heart diseases	0.824	0.176
I08 Multiple valve diseases	0.823	0.177
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.823	0.177
C51-C58 Malignant neoplasms of female genital organs	0.823	0.177
M13.97 Arthritis, unspecified (Ankle and foot)	0.822	0.178
D70 Agranulocytosis	0.821	0.179
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.820	0.180
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.820	0.180
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.818	0.182
Z83.7 Family history of diseases of the digestive system	0.818	0.182
M81 Osteoporosis without pathological fracture	0.817	0.183
M79.65 Pain in limb (Pelvic region and thigh)	0.817	0.183
R20 Disturbances of skin sensation	0.813	0.187
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.810	0.190
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.809	0.191
D50 Iron deficiency anaemia	0.809	0.191
J03 Acute tonsillitis	0.809	0.191
M06.4 Inflammatory polyarthropathy	0.808	0.192
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.808	0.192
T39.1 4-Aminophenol derivatives	0.806	0.194
J32.0 Chronic maxillary sinusitis	0.805	0.195
C43 Malignant melanoma of skin	0.803	0.197
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.803	0.197
M91-M94 Chondropathies	0.802	0.198
Z30.1 Insertion of (intra-uterine) contraceptive device	0.800	0.200
M48.09 Spinal stenosis (Site unspecified)	0.796	0.203
M22 Disorders of patella	0.795	0.205
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.795	0.205
Z93.2 Ileostomy status	0.795	0.205
R68 Other general symptoms and signs	0.793	0.206
J34.0 Abscess, furuncle and carbuncle of nose	0.790	0.210
I73 Other peripheral vascular diseases	0.789	0.211
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.787	0.213
L00-L08 Infections of the skin and subcutaneous tissue	0.785	0.215
M65-M68 Disorders of synovium and tendon	0.784	0.216
R57 Shock, not elsewhere classified	0.784	0.216
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.782	0.218
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.782	0.218
A50-A64 Infections with a predominantly sexual mode of transmission	0.782	0.218
M40-M43 Deforming dorsopathies	0.780	0.220
Z51.8 Other specified medical care	0.780	0.220
I25.5 Ischaemic cardiomyopathy	0.780	0.220
Z39 Postpartum care and examination	0.778	0.222
I78 Diseases of capillaries	0.778	0.222
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.777	0.223
L80-L99 Other disorders of the skin and subcutaneous tissue	0.776	0.224
J40-J47 Chronic lower respiratory diseases	0.776	0.224
Z49 Care involving dialysis	0.776	0.224
S61 Open wound of wrist and hand	0.775	0.224
M79.60 Pain in limb (Multiple sites)	0.775	0.225
M71 Other bursopathies	0.775	0.225
R52.1 Chronic intractable pain	0.775	0.225
Z83.3 Family history of diabetes mellitus	0.774	0.225
M80 Osteoporosis with pathological fracture	0.774	0.226
Z50.0 Cardiac rehabilitation	0.774	0.226
I64 Stroke, not specified as haemorrhage or infarction	0.772	0.228
M25.51 Pain in joint (Shoulder region)	0.772	0.228
Z90.6 Acquired absence of other parts of urinary tract	0.772	0.228
S90-S99 Injuries to the ankle and foot	0.770	0.230
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.770	0.230
M70 Soft tissue disorders related to use, overuse and pressure	0.770	0.230
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.769	0.231
B20-B24 Human immunodeficiency virus [HIV] disease	0.769	0.231
M85 Other disorders of bone density and structure	0.769	0.231
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.769	0.231
C50-C50 Malignant neoplasm of breast	0.769	0.231
Z98 Other postsurgical states	0.768	0.232
T51 Toxic effect of alcohol	0.766	0.234
M54.99 Dorsalgia, unspecified (Site unspecified)	0.765	0.235
M79.62 Pain in limb (Upper arm)	0.765	0.235
M46 Other inflammatory spondylopathies	0.764	0.236
I25.8 Other forms of chronic ischaemic heart disease	0.763	0.237
I25.3 Aneurysm of heart	0.763	0.237
J30 Vasomotor and allergic rhinitis	0.763	0.237
Z92.4 Personal history of major surgery, not elsewhere classified	0.762	0.238
M13.0 Polyarthritis, unspecified	0.761	0.238
Z91.6 Personal history of other physical trauma	0.761	0.239
I95-I99 Other and unspecified disorders of the circulatory system	0.759	0.241
M19 Other arthrosis	0.758	0.241
Z51.9 Medical care, unspecified	0.758	0.242
S00-S09 Injuries to the head	0.758	0.242
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.758	0.242
M47.96 Spondylosis, unspecified (Lumbar region)	0.757	0.243
D51 Vitamin B12 deficiency anaemia	0.757	0.243
R59.0 Localised enlarged lymph nodes	0.756	0.244
M20.3 Other deformity of hallux (acquired)	0.756	0.244
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.756	0.244
M86-M90 Other osteopathies	0.755	0.245
Z87 Personal history of other diseases and conditions	0.755	0.245
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.755	0.245
Z34.8 Supervision of other normal pregnancy	0.754	0.246
I71 Aortic aneurysm and dissection	0.753	0.247
M21 Other acquired deformities of limbs	0.751	0.248
S68 Traumatic amputation of wrist and hand	0.751	0.248
T43.5 Other and unspecified antipsychotics and neuroleptics	0.751	0.249
Z33 Pregnant state, incidental	0.750	0.249
Z51.3 Blood transfusion without reported diagnosis	0.750	0.250
M11 Other crystal arthropathies	0.750	0.250
J35 Chronic diseases of tonsils and adenoids	0.749	0.251
M54.3 Sciatica	0.749	0.251
Z40 Prophylactic surgery	0.749	0.251
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.748	0.252
Z47 Other orthopaedic follow-up care	0.747	0.253
A80-A89 Viral infections of the central nervous system	0.747	0.253
C92.0 Acute myeloid leukaemia	0.747	0.253
M50.3 Other cervical disk degeneration	0.746	0.254
R63.8 Other symptoms and signs concerning food and fluid intake	0.746	0.254
M05.9 Seropositive rheumatoid arthritis, unspecified	0.745	0.255
M50.1 Cervical disk disorder with radiculopathy	0.745	0.255
S62.6 Fracture of other finger	0.745	0.255
Z90.0 Acquired absence of part of head and neck	0.744	0.256
M48.02 Spinal stenosis (Cervical region)	0.743	0.257
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.742	0.258
Chapter V Mental and behavioural disorders	0.741	0.259
I08.1 Disorders of both mitral and tricuspid valves	0.741	0.259
C91 Lymphoid leukaemia	0.740	0.260
S69 Other and unspecified injuries of wrist and hand	0.739	0.261
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.738	0.262
S70-S79 Injuries to the hip and thigh	0.737	0.263
C44.2 Skin of ear and external auricular canal	0.735	0.265
Z46 Fitting and adjustment of other devices	0.734	0.266
M51.9 Intervertebral disk disorder, unspecified	0.733	0.267
D06 Carcinoma in situ of cervix uteri	0.732	0.268
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.730	0.270
M20.4 Other hammer toe(s) (acquired)	0.730	0.270
Z51.1 Chemotherapy session for neoplasm	0.730	0.270
A41 Other septicaemia	0.730	0.270
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.730	0.270
M54.1 Radiculopathy	0.729	0.271
M81.9 Osteoporosis, unspecified	0.728	0.272
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.728	0.272
M07 Psoriatic and enteropathic arthropathies	0.728	0.272
Z80.3 Family history of malignant neoplasm of breast	0.727	0.273
M25.9 Joint disorder, unspecified	0.727	0.273
Chapter XXII Codes for special purposes	0.727	0.273
S40-S49 Injuries to the shoulder and upper arm	0.727	0.273
M47.89 Other spondylosis (Site unspecified)	0.727	0.273
S20-S29 Injuries to the thorax	0.727	0.273
B90-B94 Sequelae of infectious and parasitic diseases	0.726	0.274
M13.96 Arthritis, unspecified (Lower leg)	0.726	0.274
M16 Coxarthrosis [arthrosis of hip]	0.726	0.274
C83 Diffuse non-Hodgkin's lymphoma	0.726	0.274
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.725	0.275
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.723	0.277
G30-G32 Other degenerative diseases of the nervous system	0.723	0.277
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.723	0.277
M84 Disorders of continuity of bone	0.722	0.278
R61.9 Hyperhidrosis, unspecified	0.722	0.278
M79.5 Residual foreign body in soft tissue	0.722	0.278
M24.0 Loose body in joint	0.721	0.279
C64-C68 Malignant neoplasms of urinary tract	0.721	0.279
J03.9 Acute tonsillitis, unspecified	0.720	0.280
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.719	0.281
M79.7 Fibromyalgia	0.719	0.281
I70 Atherosclerosis	0.718	0.282
G40-G47 Episodic and paroxysmal disorders	0.718	0.282
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.717	0.283
I05 Rheumatic mitral valve diseases	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M14 Arthropathies in other diseases classified elsewhere	0.717	0.283
M12 Other specific arthropathies	0.717	0.283
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283
M08 Juvenile arthritis	0.717	0.283
T79-T79 Certain early complications of trauma	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
M49 Spondylopathies in diseases classified elsewhere	0.717	0.283
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.716	0.284
R62 Lack of expected normal physiological development	0.716	0.284
R64 Cachexia	0.716	0.284
R58 Haemorrhage, not elsewhere classified	0.716	0.284
M53 Other dorsopathies, not elsewhere classified	0.716	0.284
M06.8 Other specified rheumatoid arthritis	0.716	0.284
M06.3 Rheumatoid nodule	0.716	0.284
M06.2 Rheumatoid bursitis	0.716	0.284
M06.1 Adult-onset Still's disease	0.716	0.284
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.284
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.716	0.284
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.716	0.284
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.716	0.284
T46 Poisoning by agents primarily affecting the cardiovascular system	0.716	0.284
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.716	0.284
T41 Poisoning by anaesthetics and therapeutic gases	0.716	0.284
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.716	0.284
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.716	0.284
T36 Poisoning by systemic antibiotics	0.716	0.284
Z89 Acquired absence of limb	0.715	0.285
Z84 Family history of other conditions	0.715	0.285
Z81 Family history of mental and behavioural disorders	0.715	0.285
M47.2 Other spondylosis with radiculopathy	0.715	0.285
I00-I02 Acute rheumatic fever	0.715	0.285
C44.7 Skin of lower limb, including hip	0.715	0.285
M48.9 Spondylopathy, unspecified	0.714	0.286
M48.8 Other specified spondylopathies	0.714	0.286
M48.5 Collapsed vertebra, not elsewhere classified	0.714	0.286
M48.4 Fatigue fracture of vertebra	0.714	0.286
M48.3 Traumatic spondylopathy	0.714	0.286
M48.2 Kissing spine	0.714	0.286
M48.1 Ankylosing hyperostosis [Forestier]	0.714	0.286
R63.6 Insufficient intake of food and water due to self neglect	0.714	0.286
R63.5 Abnormal weight gain	0.714	0.286
R63.3 Feeding difficulties and mismanagement	0.714	0.286
R63.2 Polyphagia	0.714	0.286
R63.1 Polydipsia	0.714	0.286
A49 Bacterial infection of unspecified site	0.714	0.286
M54.8 Other dorsalgia	0.713	0.286
M54.6 Pain in thoracic spine	0.713	0.286
M54.4 Lumbago with sciatica	0.713	0.286
M54.0 Panniculitis affecting regions of neck and back	0.713	0.286
B95-B98 Bacterial, viral and other infectious agents	0.713	0.287
M06.98 Rheumatoid arthritis, unspecified (Other)	0.713	0.287
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.713	0.287
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.713	0.287
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.713	0.287
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.713	0.287
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.713	0.287
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.712	0.288
M48.05 Spinal stenosis (Thoracolumbar region)	0.712	0.288
M48.04 Spinal stenosis (Thoracic region)	0.712	0.288
M48.03 Spinal stenosis (Cervicothoracic region)	0.712	0.288
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.712	0.288
M48.00 Spinal stenosis (Multiple sites in spine)	0.712	0.288
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.712	0.288
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.712	0.288
M34 Systemic sclerosis	0.712	0.288
M33 Dermatopolymyositis	0.712	0.288
M32 Systemic lupus erythematosus	0.712	0.288
M30 Polyarteritis nodosa and related conditions	0.712	0.288
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.711	0.288
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.711	0.288
C40-C41 Malignant neoplasms of bone and articular cartilage	0.711	0.288
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.711	0.288
Z36 Antenatal screening	0.711	0.289
T42.4 Benzodiazepines	0.711	0.289
M23 Internal derangement of knee	0.711	0.289
R20.2 Paraesthesia of skin	0.711	0.289
C44.6 Skin of upper limb, including shoulder	0.709	0.291
M54.2 Cervicalgia	0.709	0.291
M54.55 Low back pain (Thoracolumbar region)	0.708	0.291
M54.54 Low back pain-Thoracic	0.708	0.291
M54.53 Low back pain-Cervicothoracic	0.708	0.291
M54.52 Low back pain-Cervical	0.708	0.291
M54.51 Low back pain-Occipit-atl-axl	0.708	0.291
M54.50 Low back pain (Multiple sites in spine)	0.708	0.291
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.707	0.293
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.707	0.293
M47.1 Other spondylosis with myelopathy	0.706	0.293
M47.0 Anterior spinal and vertebral artery compression syndromes	0.706	0.293
I24.8 Other forms of acute ischaemic heart disease	0.706	0.294
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.706	0.294
T90 Sequelae of injuries of head	0.705	0.294
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.705	0.295
Z94.0 Kidney transplant status	0.704	0.296
Z54 Convalescence	0.704	0.296
Z44 Fitting and adjustment of external prosthetic device	0.704	0.296
M50.0 Cervical disk disorder with myelopathy	0.704	0.296
M45.X9 Ankylosing spondylitis (Site unspecified)	0.703	0.297
T50.9 Other and unspecified drugs, medicaments and biological substances	0.703	0.297
I23 Certain current complications following acute myocardial infarction	0.703	0.297
D50.9 Iron deficiency anaemia, unspecified	0.702	0.298
C53 Malignant neoplasm of cervix uteri	0.701	0.299
Z51.6 Desensitisation to allergens	0.701	0.299
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.701	0.299
D80-D89 Certain disorders involving the immune mechanism	0.700	0.300
M20.1 Hallux valgus (acquired)	0.700	0.300
C43.6 Malignant melanoma of upper limb, including shoulder	0.699	0.301
Z80.5 Family history of malignant neoplasm of urinary tract	0.697	0.303
J37 Chronic laryngitis and laryngotracheitis	0.697	0.303
R90 Abnormal findings on diagnostic imaging of central nervous system	0.697	0.303
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.697	0.303
I25.6 Silent myocardial ischaemia	0.697	0.303
I25.4 Coronary artery aneurysm	0.697	0.303
I25.0 Atherosclerotic cardiovascular disease, so described	0.697	0.303
A08 Viral and other specified intestinal infections	0.696	0.304
G50-G59 Nerve, nerve root and plexus disorders	0.696	0.304
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.695	0.304
D03 Melanoma in situ	0.695	0.305
M77 Other enthesopathies	0.695	0.305
R94 Abnormal results of function studies	0.694	0.306
M25.4 Effusion of joint	0.694	0.306
B99-B99 Other infectious diseases	0.694	0.306
B85-B89 Pediculosis, acariasis and other infestations	0.694	0.306
B65-B83 Helminthiases	0.694	0.306
B50-B64 Protozoal diseases	0.694	0.306
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.694	0.306
A75-A79 Rickettsioses	0.694	0.306
A70-A74 Other diseases caused by chlamydiae	0.694	0.306
A65-A69 Other spirochaetal diseases	0.694	0.306
A20-A28 Certain zoonotic bacterial diseases	0.694	0.306
A15-A19 Tuberculosis	0.694	0.306
A04 Other bacterial intestinal infections	0.694	0.306
S67 Crushing injury of wrist and hand	0.694	0.306
S65 Injury of blood vessels at wrist and hand level	0.694	0.306
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.694	0.306
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.694	0.306
R59.1 Generalised enlarged lymph nodes	0.693	0.307
Z80.9 Family history of malignant neoplasm, unspecified	0.692	0.308
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.692	0.308
Z80.6 Family history of leukaemia	0.692	0.308
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.692	0.308
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.692	0.308
M10 Gout	0.692	0.308
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.692	0.308
B25-B34 Other viral diseases	0.691	0.309
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.691	0.309
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.691	0.309
M47.94 Spondylosis, unspecified (Thoracic region)	0.691	0.309
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.691	0.309
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.691	0.309
T43.9 Psychotropic drug, unspecified	0.691	0.309
T43.8 Other psychotropic drugs, not elsewhere classified	0.691	0.309
T43.6 Psychostimulants with abuse potential	0.691	0.309
T43.4 Butyrophenone and thioxanthene neuroleptics	0.691	0.309
T43.3 Phenothiazine antipsychotics and neuroleptics	0.691	0.309
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.691	0.309
I73.9 Peripheral vascular disease, unspecified	0.690	0.310
M76 Enthesopathies of lower limb, excluding foot	0.690	0.310
M73 Soft tissue disorders in diseases classified elsewhere	0.690	0.310
L03 Cellulitis	0.690	0.310
C90 Multiple myeloma and malignant plasma cell neoplasms	0.689	0.311
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.689	0.311
D55-D59 Haemolytic anaemias	0.688	0.311
M13.8 Other specified arthritis	0.687	0.312
M13.1 Monoarthritis, not elsewhere classified	0.687	0.312
J34.1 Cyst and mucocele of nose and nasal sinus	0.687	0.313
Z93.3 Colostomy status	0.687	0.313
J20-J22 Other acute lower respiratory infections	0.687	0.313
R20.8 Other and unspecified disturbances of skin sensation	0.687	0.313
Z97.0 Presence of artificial eye	0.685	0.315
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.685	0.315
I07 Rheumatic tricuspid valve diseases	0.685	0.315
B35-B49 Mycoses	0.685	0.315
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.685	0.315
M19.0 Primary arthrosis of other joints	0.685	0.315
S62.3 Fracture of other metacarpal bone	0.684	0.315
Z98.1 Arthrodesis status	0.684	0.316
M25.8 Other specified joint disorders	0.684	0.316
T63 Toxic effect of contact with venomous animals	0.684	0.316
Z94.8 Other transplanted organ and tissue status	0.683	0.317
Z29 Need for other prophylactic measures	0.683	0.317
M20.6 Acquired deformity of toe(s), unspecified	0.683	0.317
I62 Other nontraumatic intracranial haemorrhage	0.682	0.318
M31 Other necrotising vasculopathies	0.682	0.318
S60 Superficial injury of wrist and hand	0.681	0.319
J06 Acute upper respiratory infections of multiple and unspecified sites	0.681	0.319
R52.9 Pain, unspecified	0.681	0.319
R52.0 Acute pain	0.681	0.319
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.681	0.319
I72 Other aneurysm	0.681	0.319
M47.82 Other spondylosis (Cervical region)	0.680	0.320
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.679	0.321
T66-T78 Other and unspecified effects of external causes	0.679	0.321
Z38 Liveborn infants according to place of birth	0.679	0.321
Z32 Pregnancy examination and test	0.679	0.321
Z31 Procreative management	0.679	0.321
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.678	0.322
J02 Acute pharyngitis	0.678	0.322
M25.6 Stiffness of joint, not elsewhere classified	0.678	0.322
M25.3 Other instability of joint	0.678	0.322
M25.2 Flail joint	0.678	0.322
M25.1 Fistula of joint	0.678	0.322
M25.0 Haemarthrosis	0.678	0.322

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations