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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs629301
log Bayes Factor = 128.409
Chromosome 1   position 109,818,306  (GRCh37) Explore rs629301 on Ensembl!
Variant rs629301 is listed in the   GWAS Catalog   ⇪
Variant rs629301 is part of Cluster X0034

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.5 Hyperlipidaemia, unspecified
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.000 1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.000 1.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.000 1.000
I20.0 Unstable angina
0.000 0.000 1.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.001 0.999
Z95.0 Presence of cardiac pacemaker
0.000 0.016 0.984
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.021 0.979
I21.4 Acute subendocardial myocardial infarction
0.000 0.055 0.945
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.071 0.929
E78.8 Other disorders of lipoprotein metabolism
0.000 0.073 0.927
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.080 0.920
I71 Aortic aneurysm and dissection
0.000 0.081 0.919
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.087 0.913
I73 Other peripheral vascular diseases
0.000 0.090 0.910
I73.9 Peripheral vascular disease, unspecified
0.000 0.093 0.907
Chapter IX Diseases of the circulatory system
0.000 0.100 0.900
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.107 0.893
I74 Arterial embolism and thrombosis
0.000 0.119 0.881
I25.3 Aneurysm of heart
0.000 0.124 0.876
I24 Other acute ischaemic heart diseases
0.000 0.138 0.862
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.144 0.856
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.159 0.841
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.197 0.803
E78.4 Other hyperlipidaemia
0.000 0.202 0.798
E78.6 Lipoprotein deficiency
0.000 0.212 0.788
E78.2 Mixed hyperlipidaemia
0.000 0.214 0.786
I24.8 Other forms of acute ischaemic heart disease
0.000 0.232 0.768
I25.4 Coronary artery aneurysm
0.000 0.233 0.767
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.253 0.747
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.253 0.747
I22 Subsequent myocardial infarction
0.000 0.254 0.746
I20.8 Other forms of angina pectoris
0.000 0.255 0.745
I23 Certain current complications following acute myocardial infarction
0.000 0.273 0.727
I70 Atherosclerosis
0.000 0.281 0.719
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E78.3 Hyperchylomicronaemia
0.000 0.283 0.717
E78.1 Pure hyperglyceridaemia
0.000 0.285 0.715
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.287 0.713
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.292 0.708
I50 Heart failure
0.000 0.300 0.700
I30-I52 Other forms of heart disease
0.000 0.304 0.696
I25.5 Ischaemic cardiomyopathy
0.000 0.307 0.693
I72 Other aneurysm
0.000 0.321 0.679
I50.0 Congestive heart failure
0.000 0.322 0.678
I50.1 Left ventricular failure
0.000 0.325 0.675
I35.0 Aortic (valve) stenosis
0.000 0.326 0.674
I74.8 Embolism and thrombosis of other arteries
0.000 0.326 0.674
I35 Nonrheumatic aortic valve disorders
0.000 0.327 0.673
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.327 0.673
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.341 0.659
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.341 0.659
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.341 0.659
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.348 0.652
I77 Other disorders of arteries and arterioles
0.000 0.352 0.648
I00-I02 Acute rheumatic fever
0.000 0.360 0.640
I73.8 Other specified peripheral vascular diseases
0.000 0.360 0.640
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.368 0.632
Z95.2 Presence of prosthetic heart valve
0.000 0.373 0.627
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.378 0.622
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.380 0.619
I20.1 Angina pectoris with documented spasm
0.000 0.386 0.614
I50.9 Heart failure, unspecified
0.000 0.386 0.614
I72.4 Aneurysm of artery of lower extremity
0.000 0.403 0.597
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.407 0.593
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.407 0.593
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.416 0.584
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.424 0.576
I79.1 Aortitis in diseases classified elsewhere
0.000 0.424 0.576
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.424 0.576
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.430 0.570
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.436 0.564
I45 Other conduction disorders
0.000 0.439 0.561
I71.0 Dissection of aorta [any part]
0.000 0.443 0.557
I24.1 Dressler's syndrome
0.000 0.449 0.550
I72.3 Aneurysm of iliac artery
0.000 0.450 0.550
I45.1 Other and unspecified right bundle-branch block
0.000 0.451 0.549
I22.8 Subsequent myocardial infarction of other sites
0.000 0.466 0.534
I46 Cardiac arrest
0.000 0.467 0.533
I23.8 Other current complications following acute myocardial infarction
0.000 0.469 0.531
I35.8 Other aortic valve disorders
0.000 0.472 0.528
I77.1 Stricture of artery
0.000 0.476 0.524
I70.1 Atherosclerosis of renal artery
0.000 0.476 0.523
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.479 0.521
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.479 0.521
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.479 0.521
I70.8 Atherosclerosis of other arteries
0.000 0.481 0.518
I34 Nonrheumatic mitral valve disorders
0.000 0.482 0.518
I10-I15 Hypertensive diseases
0.000 0.482 0.518
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.484 0.516
I70.9 Generalised and unspecified atherosclerosis
0.000 0.484 0.516
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.487 0.513
I33 Acute and subacute endocarditis
0.000 0.492 0.508
I40 Acute myocarditis
0.000 0.494 0.506
I72.2 Aneurysm of renal artery
0.000 0.500 0.500
I52 Other heart disorders in diseases classified elsewhere
0.000 0.501 0.499
I48 Atrial fibrillation and flutter
0.000 0.501 0.499
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.501 0.499
I41 Myocarditis in diseases classified elsewhere
0.000 0.501 0.499
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.501 0.499
I32 Pericarditis in diseases classified elsewhere
0.000 0.501 0.499
I42 Cardiomyopathy
0.000 0.504 0.496
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.513 0.487
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.513 0.487
I34.1 Mitral (valve) prolapse
0.000 0.515 0.485
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.515 0.485
I74.5 Embolism and thrombosis of iliac artery
0.000 0.518 0.482
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.522 0.478
I21.3 Acute transmural myocardial infarction of unspecified site
0.001 0.524 0.476
I77.6 Arteritis, unspecified
0.000 0.526 0.474
I77.2 Rupture of artery
0.000 0.526 0.473
I78 Diseases of capillaries
0.000 0.527 0.473
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.530 0.470
I77.5 Necrosis of artery
0.000 0.535 0.465
I77.4 Coeliac artery compression syndrome
0.000 0.535 0.465
I77.3 Arterial fibromuscular dysplasia
0.000 0.535 0.465
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.536 0.464
I70.0 Atherosclerosis of aorta
0.000 0.536 0.464
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.539 0.461
I02 Rheumatic chorea
0.000 0.541 0.459
I01 Rheumatic fever with heart involvement
0.000 0.541 0.459
I46.0 Cardiac arrest with successful resuscitation
0.000 0.545 0.455
I00 Rheumatic fever without mention of heart involvement
0.000 0.546 0.454
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.547 0.453
I45.2 Bifascicular block
0.000 0.553 0.447
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.555 0.444
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.562 0.438
I15 Secondary hypertension
0.000 0.562 0.438
I72.8 Aneurysm of other specified arteries
0.000 0.562 0.437
I42.8 Other cardiomyopathies
0.000 0.569 0.431
I77.8 Other specified disorders of arteries and arterioles
0.000 0.573 0.427
I72.1 Aneurysm of artery of upper extremity
0.000 0.576 0.424
I72.9 Aneurysm of unspecified site
0.000 0.577 0.422
I11 Hypertensive heart disease
0.000 0.585 0.415
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.585 0.415
I42.2 Other hypertrophic cardiomyopathy
0.000 0.592 0.407
I33.0 Acute and subacute infective endocarditis
0.000 0.594 0.406
I45.0 Right fascicular block
0.000 0.598 0.402
I30 Acute pericarditis
0.000 0.601 0.399
I45.5 Other specified heart block
0.000 0.604 0.396
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.609 0.391
I45.3 Trifascicular block
0.000 0.613 0.387
I37 Pulmonary valve disorders
0.000 0.613 0.386
I35.9 Aortic valve disorder, unspecified
0.000 0.614 0.386
Z82.2 Family history of deafness and hearing loss
0.000 0.615 0.385
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.616 0.384
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.617 0.383
I38 Endocarditis, valve unspecified
0.000 0.617 0.383
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.617 0.383
I46.1 Sudden cardiac death, so described
0.000 0.618 0.382
I77.0 Arteriovenous fistula, acquired
0.000 0.623 0.376
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.624 0.375
I72.0 Aneurysm of carotid artery
0.000 0.625 0.375
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.625 0.375
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.627 0.373
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.628 0.372
I13 Hypertensive heart and renal disease
0.000 0.628 0.371
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.630 0.370
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.630 0.370
I40.0 Infective myocarditis
0.000 0.630 0.370
I28 Other diseases of pulmonary vessels
0.000 0.633 0.366
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.637 0.363
I40.9 Acute myocarditis, unspecified
0.000 0.637 0.363
I40.8 Other acute myocarditis
0.000 0.637 0.363
I40.1 Isolated myocarditis
0.000 0.637 0.363
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.642 0.358
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.642 0.358
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.642 0.358
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.642 0.358
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.642 0.358
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.642 0.358
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.642 0.358
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.642 0.358
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.642 0.358
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.642 0.358
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.642 0.358
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.642 0.358
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.642 0.358
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.642 0.358
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.642 0.358
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.642 0.358
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.642 0.358
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.642 0.358
I48.4 Atypical atrial flutter
0.000 0.642 0.358
I48.3 Typical atrial flutter
0.000 0.642 0.358
I48.2 Chronic atrial fibrillation
0.000 0.642 0.358
I48.1 Persistent atrial fibrillation
0.000 0.642 0.358
I48.0 Paroxysmal atrial fibrillation
0.000 0.642 0.358
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.642 0.358
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.642 0.358
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.642 0.358
I15.1 Hypertension secondary to other renal disorders
0.000 0.642 0.358
I36 Nonrheumatic tricuspid valve disorders
0.001 0.643 0.356
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.644 0.356
I42.5 Other restrictive cardiomyopathy
0.000 0.644 0.356
I42.4 Endocardial fibroelastosis
0.000 0.644 0.356
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.644 0.356
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.650 0.350
I15.9 Seconday hypertension, unspecified
0.000 0.651 0.349
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.652 0.348
I42.6 Alcoholic cardiomyopathy
0.000 0.655 0.345
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.659 0.341
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.660 0.340
I78.9 Disease of capillaries, unspecified
0.000 0.661 0.339
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.661 0.339
Z95.3 Presence of xenogenic heart valve
0.000 0.661 0.338
I34.0 Mitral (valve) insufficiency
0.000 0.663 0.337
I05-I09 Chronic rheumatic heart diseases
0.000 0.667 0.333
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.667 0.332
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.671 0.329
I01.8 Other acute rheumatic heart disease
0.000 0.671 0.329
I01.2 Acute rheumatic myocarditis
0.000 0.671 0.329
I01.1 Acute rheumatic endocarditis
0.000 0.671 0.329
I01.0 Acute rheumatic pericarditis
0.000 0.671 0.329
I02.9 Rheumatic chorea without heart involvement
0.000 0.671 0.329
I02.0 Rheumatic chorea with heart involvement
0.000 0.671 0.329
I78.8 Other diseases of capillaries
0.000 0.672 0.328
I45.9 Conduction disorder, unspecified
0.000 0.677 0.323
I33.9 Acute endocarditis, unspecified
0.000 0.680 0.320
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.683 0.317
I15.8 Other secondary hypertension
0.000 0.686 0.314
I15.2 Hypertension secondary to endocrine disorders
0.000 0.686 0.314
I15.0 Renovascular hypertension
0.000 0.686 0.314
Z82.1 Family history of blindness and visual loss
0.000 0.688 0.311
I28.8 Other specified diseases of pulmonary vessels
0.000 0.689 0.310
I46.9 Cardiac arrest, unspecified
0.000 0.692 0.308
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.695 0.305
S00.8 Superficial injury of other parts of head
0.000 0.696 0.304
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.699 0.301
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.706 0.294
I42.9 Cardiomyopathy, unspecified
0.000 0.706 0.294
I45.4 Nonspecific intraventricular block
0.000 0.707 0.293
I99 Other and unspecified disorders of circulatory system
0.000 0.708 0.292
I30.8 Other forms of acute pericarditis
0.000 0.714 0.286
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.714 0.286
I45.8 Other specified conduction disorders
0.000 0.719 0.280
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.720 0.280
I37.9 Pulmonary valve disorder, unspecified
0.000 0.723 0.277
I37.8 Other pulmonary valve disorders
0.000 0.723 0.277
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.723 0.277
I37.0 Pulmonary valve stenosis
0.000 0.723 0.277
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.733 0.266
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.733 0.266
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.733 0.266
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.733 0.266
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.735 0.265
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.737 0.263
I28.1 Aneurysm of pulmonary artery
0.000 0.737 0.263
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.737 0.263
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.001 0.744 0.256
I36.8 Other nonrheumatic tricuspid valve disorders
0.001 0.744 0.256
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.001 0.744 0.256
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.001 0.744 0.256
S00 Superficial injury of head
0.000 0.744 0.256
I09 Other rheumatic heart diseases
0.000 0.751 0.249
I30.1 Infective pericarditis
0.000 0.752 0.247
I45.6 Preexcitation syndrome
0.000 0.759 0.240
I30.9 Acute pericarditis, unspecified
0.000 0.759 0.240
O34.2 Maternal care due to uterine scar from previous surgery
0.238 0.762 0.000
I73.0 Raynaud's syndrome
0.000 0.763 0.237
S00.0 Superficial injury of scalp
0.000 0.765 0.235
I06 Rheumatic aortic valve diseases
0.000 0.767 0.232
S00.7 Multiple superficial injuries of head
0.000 0.774 0.226
I07 Rheumatic tricuspid valve diseases
0.000 0.777 0.223
I10 Essential (primary) hypertension
0.000 0.780 0.220
I97.1 Other functional disturbances following cardiac surgery
0.000 0.785 0.215
I27 Other pulmonary heart diseases
0.000 0.796 0.204
I05 Rheumatic mitral valve diseases
0.000 0.806 0.194
I31 Other diseases of pericardium
0.000 0.808 0.192
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.810 0.190
I97.0 Postcardiotomy syndrome
0.000 0.810 0.190
I09.9 Rheumatic heart disease, unspecified
0.000 0.811 0.189
S00.2 Other superficial injuries of eyelid and periocular area
0.000 0.811 0.189
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.814 0.186
S00.1 Contusion of eyelid and periocular area
0.000 0.818 0.182
S00.3 Superficial injury of nose
0.000 0.820 0.180
I09.8 Other specified rheumatic heart diseases
0.000 0.821 0.179
I09.2 Chronic rheumatic pericarditis
0.000 0.821 0.179
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.821 0.179
I09.0 Rheumatic myocarditis
0.000 0.821 0.179
S00.5 Superficial injury of lip and oral cavity
0.000 0.821 0.179
I42.0 Dilated cardiomyopathy
0.000 0.826 0.173
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.827 0.173
I95 Hypotension
0.000 0.827 0.173
I26 Pulmonary embolism
0.002 0.829 0.169
I12 Hypertensive renal disease
0.000 0.832 0.168
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.833 0.167
I06.8 Other rheumatic aortic valve diseases
0.000 0.833 0.167
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.833 0.167
I06.0 Rheumatic aortic stenosis
0.000 0.833 0.167
I78.1 Naevus, nonneoplastic
0.000 0.834 0.166
I37.1 Pulmonary valve insufficiency
0.001 0.835 0.165
I27.9 Pulmonary heart disease, unspecified
0.000 0.839 0.161
I07.9 Tricuspid valve disease, unspecified
0.000 0.840 0.160
I07.8 Other tricuspid valve diseases
0.000 0.840 0.160
I07.2 Tricuspid stenosis with insufficiency
0.000 0.840 0.160
I07.0 Tricuspid stenosis
0.000 0.840 0.160
I06.1 Rheumatic aortic insufficiency
0.000 0.840 0.160
I05.2 Mitral stenosis with insufficiency
0.000 0.840 0.160
S00.4 Superficial injury of ear
0.000 0.843 0.157
I27.8 Other specified pulmonary heart diseases
0.000 0.848 0.152
S00.9 Superficial injury of head, part unspecified
0.000 0.848 0.152
I51 Complications and ill-defined descriptions of heart disease
0.000 0.851 0.149
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.853 0.147
I27.1 Kyphoscoliotic heart disease
0.000 0.854 0.146
I07.1 Tricuspid insufficiency
0.000 0.855 0.144
Z82.3 Family history of stroke
0.000 0.858 0.142
O34 Maternal care for known or suspected abnormality of pelvic organs
0.140 0.860 0.000
I05.8 Other mitral valve diseases
0.000 0.861 0.139
I31.8 Other specified diseases of pericardium
0.000 0.862 0.138
I31.2 Haemopericardium, not elsewhere classified
0.000 0.862 0.138
I05.1 Rheumatic mitral insufficiency
0.000 0.865 0.135
I95.9 Hypotension, unspecified
0.000 0.868 0.132
I95.1 Orthostatic hypotension
0.000 0.872 0.128
I05.0 Mitral stenosis
0.000 0.874 0.126
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.876 0.124
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.876 0.124
I98.0 Cardiovascular syphilis
0.000 0.876 0.124
I51.0 Cardiac septal defect, acquired
0.000 0.882 0.118
I31.0 Chronic adhesive pericarditis
0.000 0.883 0.116
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.884 0.116
O34.0 Maternal care for congenital malformation of uterus
0.116 0.884 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.001 0.885 0.113
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.001 0.886 0.113
I31.1 Chronic constrictive pericarditis
0.000 0.886 0.114
O34.8 Maternal care for other abnormalities of pelvic organs
0.113 0.887 0.000
I49 Other cardiac arrhythmias
0.000 0.890 0.110
S00-S09 Injuries to the head
0.000 0.891 0.109
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.892 0.108
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.893 0.107
I51.9 Heart disease, unspecified
0.000 0.896 0.104
O34.1 Maternal care for tumour of corpus uteri
0.103 0.897 0.000
I95.2 Hypotension due to drugs
0.000 0.897 0.102
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.101 0.899 0.000
O34.6 Maternal care for abnormality of vagina
0.101 0.899 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.101 0.899 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.101 0.899 0.000
I31.3 Pericardial effusion (noninflammatory)
0.000 0.901 0.099
O34.3 Maternal care for cervical incompetence
0.098 0.902 0.000
I51.8 Other ill-defined heart diseases
0.000 0.903 0.097
I49.5 Sick sinus syndrome
0.000 0.903 0.097
O34.4 Maternal care for other abnormalities of cervix
0.095 0.904 0.000
Z95.4 Presence of other heart-valve replacement
0.000 0.905 0.095
S02 Fracture of skull and facial bones
0.000 0.906 0.094
I95.0 Idiopathic hypotension
0.000 0.907 0.093
I27.0 Primary pulmonary hypertension
0.000 0.907 0.093
I12.9 Hypertensive renal disease without renal failure
0.000 0.908 0.091
S02.0 Fracture of vault of skull
0.000 0.909 0.091
I51.6 Cardiovascular disease, unspecified
0.000 0.909 0.090
I51.7 Cardiomegaly
0.000 0.910 0.090
I95.8 Other hypotension
0.000 0.910 0.090
S01 Open wound of head
0.000 0.911 0.089
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.911 0.089
S02.00 Fracture of vault of skull (closed)
0.000 0.911 0.089
S01.9 Open wound of head, part unspecified
0.000 0.912 0.088
I31.9 Disease of pericardium, unspecified
0.000 0.912 0.088
I51.5 Myocardial degeneration
0.000 0.912 0.087
I08 Multiple valve diseases
0.000 0.913 0.087
I49.1 Atrial premature depolarisation
0.000 0.914 0.086
S02.2 Fracture of nasal bones
0.000 0.915 0.085
S01.7 Multiple open wounds of head
0.000 0.919 0.081
I49.2 Junctional premature depolarisation
0.000 0.921 0.079
S02.20 Fracture of nasal bones (closed)
0.000 0.921 0.079
S08 Traumatic amputation of part of head
0.000 0.922 0.078
S07 Crushing injury of head
0.000 0.922 0.078
S04 Injury of cranial nerves
0.000 0.922 0.078
I49.8 Other specified cardiac arrhythmias
0.000 0.922 0.078
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.922 0.078
I47 Paroxysmal tachycardia
0.000 0.923 0.077
S09 Other and unspecified injuries of head
0.000 0.924 0.076
I05.9 Mitral valve disease, unspecified
0.000 0.924 0.075
S05 Injury of eye and orbit
0.000 0.925 0.075
S03 Dislocation, sprain and strain of joints and ligaments of head
0.000 0.925 0.075
K05.3 Chronic periodontitis
0.074 0.926 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.929 0.071
S01.1 Open wound of eyelid and periocular area
0.000 0.929 0.071
S02.8 Fractures of other skull and facial bones
0.000 0.929 0.070
S02.7 Multiple fractures involving skull and facial bones
0.000 0.930 0.070
I35.1 Aortic (valve) insufficiency
0.001 0.930 0.069
S01.3 Open wound of ear
0.000 0.931 0.069
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.932 0.068
S09.8 Other specified injuries of head
0.000 0.935 0.065
S02.01 Fracture of vault of skull (open)
0.000 0.935 0.065
S02.6 Fracture of mandible
0.000 0.939 0.061
S02.21 Fracture of nasal bones (open)
0.000 0.939 0.061
S01.2 Open wound of nose
0.000 0.940 0.060
S05.8 Other injuries of eye and orbit
0.000 0.940 0.059
I49.4 Other and unspecified premature depolarisation
0.000 0.941 0.059
S03.2 Dislocation of tooth
0.000 0.941 0.059
S02.3 Fracture of orbital floor
0.000 0.942 0.058
S05.1 Contusion of eyeball and orbital tissues
0.000 0.943 0.057
I08.9 Multiple valve disease, unspecified
0.000 0.943 0.057
S04.9 Injury of unspecified cranial nerve
0.000 0.944 0.056
S04.8 Injury of other cranial nerves
0.000 0.944 0.056
S04.7 Injury of accessory nerve
0.000 0.944 0.056
S04.6 Injury of acoustic nerve
0.000 0.944 0.056
S04.5 Injury of facial nerve
0.000 0.944 0.056
S04.4 Injury of abducent nerve
0.000 0.944 0.056
S04.3 Injury of trigeminal nerve
0.000 0.944 0.056
S04.2 Injury of trochlear nerve
0.000 0.944 0.056
S04.1 Injury of oculomotor nerve
0.000 0.944 0.056
S04.0 Injury of optic nerve and pathways
0.000 0.944 0.056
S07.9 Crushing injury of head, part unspecified
0.000 0.944 0.056
S07.8 Crushing injury of other parts of head
0.000 0.944 0.056
S07.1 Crushing injury of skull
0.000 0.944 0.056
S07.0 Crushing injury of face
0.000 0.944 0.056
S08.9 Traumatic amputation of unspecified part of head
0.000 0.944 0.056
S08.8 Traumatic amputation of other parts of head
0.000 0.944 0.056
S08.1 Traumatic amputation of ear
0.000 0.944 0.056
S08.0 Avulsion of scalp
0.000 0.944 0.056
S09.7 Multiple injuries of head
0.000 0.945 0.055
S09.2 Traumatic rupture of ear drum
0.000 0.945 0.055
S09.1 Injury of muscle and tendon of head
0.000 0.945 0.055
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.945 0.055
S01.4 Open wound of cheek and temporomandibular area
0.000 0.945 0.055
S05.7 Avulsion of eye
0.000 0.946 0.054
S05.6 Penetrating wound of eyeball without foreign body
0.000 0.946 0.054
S05.5 Penetrating wound of eyeball with foreign body
0.000 0.946 0.054
S05.4 Penetrating wound of orbit with or without foreign body
0.000 0.946 0.054
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.000 0.946 0.054
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head
0.000 0.946 0.054
S03.4 Sprain and strain of jaw
0.000 0.946 0.054
S03.3 Dislocation of other and unspecified parts of head
0.000 0.946 0.054
S03.0 Dislocation of jaw
0.000 0.946 0.054
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.000 0.946 0.054
S05.9 Injury of eye and orbit, part unspecified
0.000 0.946 0.054
S02.80 Fractures of other skull and facial bones (closed)
0.000 0.947 0.053
I51.4 Myocarditis, unspecified
0.001 0.947 0.052
S02.70 Multiple fractures involving skull and facial bones (closed)
0.000 0.948 0.052
S02.4 Fracture of malar and maxillary bones
0.000 0.948 0.052
S02.1 Fracture of base of skull
0.000 0.948 0.052
S09.0 Injury of blood vessels of head, not elsewhere classified
0.000 0.949 0.051
S02.81 Fractures of other skull and facial bones (open)
0.000 0.949 0.051
S02.71 Multiple fractures involving skull and facial bones (open)
0.000 0.950 0.050
S02.5 Fracture of tooth
0.000 0.950 0.050
I08.8 Other multiple valve diseases
0.000 0.951 0.049
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.000 0.951 0.049
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.951 0.049
I47.0 Reentry ventricular arrhythmia
0.000 0.954 0.046
K05 Gingivitis and periodontal diseases
0.045 0.955 0.000
S03.1 Dislocation of septal cartilage of nose
0.000 0.955 0.044
I98.2 Oesophageal varices in diseases classified elsewhere
0.001 0.955 0.044
S02.61 Fracture of mandible (open)
0.000 0.956 0.044
S02.31 Fracture of orbital floor (open)
0.000 0.958 0.042
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.000 0.959 0.040
K05.6 Periodontal disease, unspecified
0.039 0.961 0.000
S02.60 Fracture of mandible (closed)
0.000 0.962 0.038
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.962 0.037
S01.5 Open wound of lip and oral cavity
0.000 0.963 0.037
I49.0 Ventricular fibrillation and flutter
0.000 0.963 0.037
S09.9 Unspecified injury of head
0.000 0.963 0.037
S02.51 Fracture of tooth (open)
0.000 0.964 0.036
K05.1 Chronic gingivitis
0.036 0.964 0.000
I47.2 Ventricular tachycardia
0.000 0.965 0.035
I60-I69 Cerebrovascular diseases
0.000 0.966 0.034
K05.2 Acute periodontitis
0.033 0.967 0.000
K05.4 Periodontosis
0.033 0.967 0.000
K05.0 Acute gingivitis
0.033 0.967 0.000
S02.30 Fracture of orbital floor (closed)
0.000 0.968 0.031
S06 Intracranial injury
0.000 0.968 0.031
S02.11 Fracture of base of skull (open)
0.000 0.969 0.031
S02.10 Fracture of base of skull (closed)
0.000 0.970 0.030
I69 Sequelae of cerebrovascular disease
0.000 0.970 0.030
K05.5 Other periodontal diseases
0.030 0.970 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.971 0.029
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.971 0.029
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.972 0.028
S06.3 Focal brain injury
0.000 0.973 0.027
I65.2 Occlusion and stenosis of carotid artery
0.000 0.974 0.026
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.975 0.024
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.976 0.024
K05.22 Aggressive periodontitis, generalized
0.024 0.976 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.977 0.023
I47.9 Paroxysmal tachycardia, unspecified
0.001 0.977 0.022
I08.0 Disorders of both mitral and aortic valves
0.000 0.977 0.023
S06.7 Intracranial injury with prolonged coma
0.000 0.977 0.023
S06.1 Traumatic cerebral oedema
0.000 0.977 0.023
S01.8 Open wound of other parts of head
0.000 0.977 0.023
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.979 0.021
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.979 0.021
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.979 0.021
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.979 0.021
S06.4 Epidural haemorrhage
0.000 0.979 0.021

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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